A property representing notations made by NCI vocabulary curators. They are intended to provide supplemental, unstructured information to the user or additional insight about the concept.
A property representing that a term in another terminology has been mapped to a term in NCIt and describes the relationship between the mapped terms.
An association that shows which Permissible Values are possible for a specific PCDC OS Variable.
An association that shows which Permissible Values are possible for a specific PCDC HL Variable.
An association that shows which Permissible Values are possible for a specific PCDC GCT Variable.
An association that that connects a concept representing a GDC value to any associated GDC property concept(s).
An association that connects the concept defining a particular terminology subset with concepts that belong to this subset.
A property representing a concept unique identifier within the NCI Enterprise Vocabulary Service's NCI Thesaurus.
A property is used to indicate when a non-EVS entity has contributed to, and has a stake in, a concept. This is used where such entities, within or outside NCI, have indicated the need to be able to track their own concepts. A single concept can have multiple instances of this property if multiple entities have such a defined stake.
A property representing a retired unique concept identifier created and stored as Concept Name by legacy EVS software. Use of these values was long discouraged, but continued as late as 2009 when creation of new values ceased and Concept Name was retired. Legacy values are intended solely to help resolve and update earlier coding.
imported from
A property representing the English language definitions of what NCI means by the concept. They may also include information about the definition's source and attribution in a form that can easily be interpreted by software.
An association that shows which Permissible Values are possible for a specific PCDC EWS Variable concept.
An association that specifies one of three data types for a particular variable, String, Code or Number.
A property representing a fully qualified synonym, contains the string, term type, source, and an optional source code if appropriate. Each subfield is deliniated to facilitate interpretation by software.
An association that shows which Permissible Values are possible for a specific DIPG/DMG Variable.
A property representing the English language definition of a concept from a source other than NCI.
A property that represents a description of the sort of thing or category to which a concept belongs in the context of the UMLS semantic network.
In general, applying semantic types aids in allowing users (or computer programs) to draw conclusions about concepts by virtue of the categories to which they have been assigned. We use a set of semantic types developed for the UMLS Metathesaurus. There are currently 134 semantic types in the UMLS.
A property representing the concept unique identifier (CUI) for those concepts that appear in NCI Metathesaurus but not in the National Library of Medicine Unified Medical Language System (NLM UMLS).
A property representing an alternative Preferred Name for use in some NCI systems.
A property representing the word or phrase that NCI uses by preference to refer to the concept.
A property representing the concept unique identifier (CUI) assigned by the National Library of Medicine (NLM). If a concept in any NCI-maintained knowledgebase exists in the NLM Unified Medical Language System (UMLS), NCI includes the NLM CUI among the information we provide about the concept.
A DNA sequencing technique in which the entirety of the individual's genome is sequenced.
A procedure that can determine the DNA sequence for nearly the entire genome of an individual.
A mouse model for human cancer studies in which a human-derived tumor sample is transplanted into an immunodeficient mouse.
A study of the effect of dose changes on the efficacy of a drug in order to determine the dose-response relationship and optimal dose of a therapy.
The determination of the strength of a material, as measured by the ability to produce a specific response. The potency of a pharmacologic substance is measured by the amount needed to produce a certain effect.
The study of the structure of the cells and their arrangement to constitute tissues and, finally, the association among these to form organs. In pathology, the microscopic process of identifying normal and abnormal morphologic characteristics in tissues, by employing various cytochemical and immunocytochemical stains.
The study of tissues and cells under a microscope.
Autoradiographic analysis performed in accordance with specified guidelines that will result in a defined correspondence between the intensity of the autoradiographic image and the amount of radioactivity present in the sample. This permits assignment of a value to the amount of radioactive material in the object under study.
Models of human disease produced through gene knockout methods
A technology used for preclinical research as an alternative to some animal testing. Micrometer-thin slices of various organs are incubated with various experimental compounds for assays involving toxicology, absorption, distribution, and metabolism.
An in vitro assay in which cultured cells are monitored and analyzed for their ability to move into an acellular area of a culture material.
An experimental system in which (usually) human tumor cells are transplanted into immunocompromised mice that do not reject human cells; cells may be implanted under the skin or into the organ type in which the tumor originated. These model systems may be used for drug development and studies of molecular biological mechanisms of cancer.
In chemistry and biology, the strength of the attaction between two substances, such as two chemicals, or an antigen and an antibody.
The strength of noncovalent chemical binding between two substances as measured by the dissociation constant of the complex.
A constant symbolizing the ratio of a dissolved substance in a two-phase system. (from EPA Terminology Reference System)
A measurement of the time from the start to cessation of an induced bleed.
The amount of time it take for a cessation of bleeding. It is a measurement of the ability of capillaries and platelets to interact to form a blood clot.