DesignNote
type: AnnotationProperty
definition: A property representing notations made by NCI vocabulary curators. They are intended to provide supplemental, unstructured information to the user or additional insight about the concept.
Semantic_Type: Conceptual Entity
Preferred_Name: DesignNote
has exact synonym: DesignNote
Display_Name: DesignNote
code: P98

Maps_To
type: AnnotationProperty
definition: A property representing that a term in another terminology has been mapped to a term in NCIt and describes the relationship between the mapped terms.
Semantic_Type: Conceptual Entity
Preferred_Name: Maps_To
has exact synonym: Maps_To
code: P375

Has_PCDC_OS_Permissible_Value
type: AnnotationProperty
code: A38
definition: An association that shows which Permissible Values are possible for a specific PCDC OS Variable.
Semantic_Type: Conceptual Entity
Preferred_Name: Has_PCDC_OS_Permissible_Value
has exact synonym: Has_PCDC_OS_Permissible_Value

Has_PCDC_HL_Permissible_Value
type: AnnotationProperty
code: A39
definition: An association that shows which Permissible Values are possible for a specific PCDC HL Variable.
Semantic_Type: Conceptual Entity
Preferred_Name: Has_PCDC_HL_Permissible_Value
has exact synonym: Has_PCDC_HL_Permissible_Value

Has_PCDC_GCT_Permissible_Value
type: AnnotationProperty
code: A34
definition: An association that shows which Permissible Values are possible for a specific PCDC GCT Variable.
Semantic_Type: Conceptual Entity
Preferred_Name: Has_PCDC_GCT_Permissible_Value
has exact synonym: Has_PCDC_GCT_Permissible_Value

Is_Value_For_GDC_Property
type: AnnotationProperty
code: A32
definition: An association that that connects a concept representing a GDC value to any associated GDC property concept(s).
Semantic_Type: Conceptual Entity
Preferred_Name: Is_Value_For_GDC_Property
has exact synonym: Is_Value_For_GDC_Property

in subset
type: AnnotationProperty
definition: An association that connects the concept defining a particular terminology subset with concepts that belong to this subset.
has exact synonym: Concept_In_Subset

code
type: AnnotationProperty
definition: A property representing a concept unique identifier within the NCI Enterprise Vocabulary Service's NCI Thesaurus.
Semantic_Type: Conceptual Entity
code: NHC0
Preferred_Name: code
has exact synonym: code
read only: true

Contributing_Source
type: AnnotationProperty
definition: A property is used to indicate when a non-EVS entity has contributed to, and has a stake in, a concept. This is used where such entities, within or outside NCI, have indicated the need to be able to track their own concepts. A single concept can have multiple instances of this property if multiple entities have such a defined stake.
Semantic_Type: Conceptual Entity
Display_Name: Contributing Source
Preferred_Name: Contributing_Source
has exact synonym: Contributing_Source
code: P322

Legacy Concept Name
type: AnnotationProperty
definition: A property representing a retired unique concept identifier created and stored as Concept Name by legacy EVS software. Use of these values was long discouraged, but continued as late as 2009 when creation of new values ceased and Concept Name was retired. Legacy values are intended solely to help resolve and update earlier coding.
Semantic_Type: Conceptual Entity
has exact synonym: Legacy Concept Name
Preferred_Name: Legacy Concept Name
has exact synonym: Legacy_Concept_Name
code: P366
read only: true

imported from
type: AnnotationProperty

definition
type: AnnotationProperty
definition: A property representing the English language definitions of what NCI means by the concept. They may also include information about the definition's source and attribution in a form that can easily be interpreted by software.
has exact synonym: DEFINITION

Has_PCDC_EWS_Permissible_Value
type: AnnotationProperty
code: A29
definition: An association that shows which Permissible Values are possible for a specific PCDC EWS Variable concept.
Semantic_Type: Conceptual Entity
has exact synonym: Has_PCDC_EWS_Permissible_Value
Preferred_Name: Has_PCDC_EWS_Permissible_Value

Has_PCDC_Data_Type
type: AnnotationProperty
code: A23
definition: An association that specifies one of three data types for a particular variable, String, Code or Number.
Semantic_Type: Conceptual Entity
Preferred_Name: Has_PCDC_Data_Type
has exact synonym: Has_PCDC_Data_Type

has exact synonym
type: AnnotationProperty
definition: A property representing a fully qualified synonym, contains the string, term type, source, and an optional source code if appropriate. Each subfield is deliniated to facilitate interpretation by software.
has exact synonym: FULL_SYN
has exact synonym: Synonym with Source Data

Has_DIPG_DMG_Permissible_Value
type: AnnotationProperty
code: A40
definition: An association that shows which Permissible Values are possible for a specific DIPG/DMG Variable.
Semantic_Type: Conceptual Entity
Preferred_Name: Has_DIPG_DMG_Permissible_Value
has exact synonym: Has_DIPG_DMG_Permissible_Value

ALT_DEFINITION
type: AnnotationProperty
definition: A property representing the English language definition of a concept from a source other than NCI.
Preferred_Name: ALT_DEFINITION
has exact synonym: ALT_DEFINITION
Semantic_Type: Conceptual Entity
code: P325
Display_Name: [source] Definition

Semantic_Type
type: AnnotationProperty
definition: A property that represents a description of the sort of thing or category to which a concept belongs in the context of the UMLS semantic network.
Semantic_Type: Conceptual Entity
DesignNote: In general, applying semantic types aids in allowing users (or computer programs) to draw conclusions about concepts by virtue of the categories to which they have been assigned. We use a set of semantic types developed for the UMLS Metathesaurus. There are currently 134 semantic types in the UMLS.
code: P106
Display_Name: Semantic Type
Preferred_Name: Semantic_Type
has exact synonym: Semantic_Type

label

NCI_META_CUI
type: AnnotationProperty
definition: A property representing the concept unique identifier (CUI) for those concepts that appear in NCI Metathesaurus but not in the National Library of Medicine Unified Medical Language System (NLM UMLS).
Semantic_Type: Conceptual Entity
Display_Name: NCI Metathesaurus CUI
has exact synonym: NCI_META_CUI
Preferred_Name: NCI_META_CUI
code: P208

Display_Name
type: AnnotationProperty
definition: A property representing an alternative Preferred Name for use in some NCI systems.
Semantic_Type: Conceptual Entity
has exact synonym: Display Name
Display_Name: Display Name
has exact synonym: Display_Name
Preferred_Name: Display_Name
code: P107

Preferred_Name
type: AnnotationProperty
definition: A property representing the word or phrase that NCI uses by preference to refer to the concept.
Semantic_Type: Conceptual Entity
code: P108
Display_Name: Preferred Name
has exact synonym: Preferred Name
has exact synonym: Preferred Term
Preferred_Name: Preferred_Name
has exact synonym: Preferred_Name

UMLS_CUI
type: AnnotationProperty
definition: A property representing the concept unique identifier (CUI) assigned by the National Library of Medicine (NLM). If a concept in any NCI-maintained knowledgebase exists in the NLM Unified Medical Language System (UMLS), NCI includes the NLM CUI among the information we provide about the concept.
Semantic_Type: Conceptual Entity
code: P207
Display_Name: UMLS CUI
Preferred_Name: UMLS_CUI
has exact synonym: UMLS_CUI

Whole Genome Sequencing
type: Class
subclass of: BAO_0002445
ALT_DEFINITION: A DNA sequencing technique in which the entirety of the individual's genome is sequenced.
definition: A procedure that can determine the DNA sequence for nearly the entire genome of an individual.
code: C101294
UMLS_CUI: C3640076
Contributing_Source: CDISC
Contributing_Source: CTDC
Contributing_Source: CTRP
Contributing_Source: GDC
Contributing_Source: ICDC
Semantic_Type: Molecular Biology Research Technique
has exact synonym: WGS
Maps_To: WGS
has exact synonym: WGS (whole genome sequencing)
has exact synonym: WHOLE GENOME SEQUENCING
Preferred_Name: Whole Genome Sequencing
Display_Name: Whole Genome Sequencing
has exact synonym: Whole Genome Sequencing
in subset: NCIT C116977
in subset: NCIT C142799
in subset: NCIT C157711
in subset: NCIT C165451
in subset: NCIT C166372
in subset: NCIT C173073
in subset: NCIT C177537
in subset: NCIT C61410
in subset: NCIT C66830
in subset: NCIT C85492
Is_Value_For_GDC_Property: NCIT C177618
Is_Value_For_GDC_Property: NCIT C19770
Is_Value_For_GDC_Property: NCIT C43622
imported from: ncit.owl

Patient Derived Xenograft
type: Class
subclass of: BAO_0010279
definition: A mouse model for human cancer studies in which a human-derived tumor sample is transplanted into an immunodeficient mouse.
code: C122936
UMLS_CUI: C4050317
Contributing_Source: CTRP
Semantic_Type: Experimental Model of Disease
has exact synonym: PDTX
has exact synonym: PDX
has exact synonym: Patient Derived Xenograft
Preferred_Name: Patient Derived Xenograft
Display_Name: Patient Derived Xenograft
has exact synonym: Patient-Derived Xenograft
has exact synonym: Patient-Derived Xenograft Model
in subset: NCIT C116977
in subset: NCIT C118169
imported from: ncit.owl

Dose Response Study
type: Class
subclass of: BAO_0010278
ALT_DEFINITION: A study of the effect of dose changes on the efficacy of a drug in order to determine the dose-response relationship and optimal dose of a therapy.
definition: A study of the effect of dose changes on the efficacy of a drug in order to determine the dose-response relationship and optimal dose of a therapy.
code: C127803
Contributing_Source: CDISC
NCI_META_CUI: CL509446
has exact synonym: DOSE RESPONSE
has exact synonym: Dose Response Study
Preferred_Name: Dose Response Study
Semantic_Type: Research Activity
in subset: NCIT C132298
in subset: NCIT C61410
in subset: NCIT C66739
in subset: NCIT C66830
imported from: ncit.owl

Potency Assay
type: Class
subclass of: BAO_0000409
code: C134270
NCI_META_CUI: CL521998
Semantic_Type: Laboratory Procedure
has exact synonym: Potency Assay
Preferred_Name: Potency Assay
definition: The determination of the strength of a material, as measured by the ability to produce a specific response. The potency of a pharmacologic substance is measured by the amount needed to produce a certain effect.
imported from: ncit.owl

Histology
type: Class
subclass of: BAO_0000448
Semantic_Type: Biomedical Occupation or Discipline
UMLS_CUI: C0019638
code: C16681
Contributing_Source: DIPG/DMG
Contributing_Source: FDA
Contributing_Source: GDC
has exact synonym: HISTOLOGY
has exact synonym: Histology
Maps_To: Histology
Preferred_Name: Histology
Legacy Concept Name: Histology
has exact synonym: Microanatomy
Contributing_Source: PCDC
definition: The study of the structure of the cells and their arrangement to constitute tissues and, finally, the association among these to form organs. In pathology, the microscopic process of identifying normal and abnormal morphologic characteristics in tissues, by employing various cytochemical and immunocytochemical stains.
ALT_DEFINITION: The study of tissues and cells under a microscope.
has exact synonym: histology
in subset: NCIT C157711
in subset: NCIT C174239
in subset: NCIT C174248
in subset: NCIT C177384
in subset: NCIT C177396
in subset: NCIT C177537
in subset: NCIT C179490
in subset: NCIT C183105
in subset: NCIT C186318
in subset: NCIT C186342
in subset: NCIT C186764
Has_DIPG_DMG_Permissible_Value: NCIT C114967
Has_PCDC_GCT_Permissible_Value: NCIT C121618
Has_PCDC_EWS_Permissible_Value: NCIT C121799
Has_DIPG_DMG_Permissible_Value: NCIT C129309
Has_PCDC_EWS_Permissible_Value: NCIT C174456
Has_PCDC_OS_Permissible_Value: NCIT C17649
Has_DIPG_DMG_Permissible_Value: NCIT C17649
Is_Value_For_GDC_Property: NCIT C177564
Has_PCDC_OS_Permissible_Value: NCIT C179410
Has_PCDC_EWS_Permissible_Value: NCIT C17998
Has_PCDC_OS_Permissible_Value: NCIT C17998
Has_PCDC_GCT_Permissible_Value: NCIT C17998
Has_PCDC_Data_Type: NCIT C25162
Has_PCDC_GCT_Permissible_Value: NCIT C2948
Has_PCDC_GCT_Permissible_Value: NCIT C3011
Has_DIPG_DMG_Permissible_Value: NCIT C3017
Has_DIPG_DMG_Permissible_Value: NCIT C3288
Has_PCDC_GCT_Permissible_Value: NCIT C3403
Has_PCDC_HL_Permissible_Value: NCIT C3517
Has_PCDC_HL_Permissible_Value: NCIT C3518
Has_PCDC_OS_Permissible_Value: NCIT C35870
Has_PCDC_GCT_Permissible_Value: NCIT C35957
Has_PCDC_GCT_Permissible_Value: NCIT C36029
Has_PCDC_GCT_Permissible_Value: NCIT C3752
Has_PCDC_GCT_Permissible_Value: NCIT C3754
Has_PCDC_OS_Permissible_Value: NCIT C3902
Has_PCDC_OS_Permissible_Value: NCIT C4020
Has_PCDC_OS_Permissible_Value: NCIT C4021
Has_PCDC_OS_Permissible_Value: NCIT C4023
Has_DIPG_DMG_Permissible_Value: NCIT C4047
Has_PCDC_GCT_Permissible_Value: NCIT C4286
Has_PCDC_GCT_Permissible_Value: NCIT C4287
Has_PCDC_GCT_Permissible_Value: NCIT C4289
Has_PCDC_GCT_Permissible_Value: NCIT C4290
Has_PCDC_OS_Permissible_Value: NCIT C43234
Has_PCDC_GCT_Permissible_Value: NCIT C43234
Has_PCDC_EWS_Permissible_Value: NCIT C43234
Has_DIPG_DMG_Permissible_Value: NCIT C5097
Has_PCDC_OS_Permissible_Value: NCIT C53953
Has_DIPG_DMG_Permissible_Value: NCIT C5817
Has_PCDC_HL_Permissible_Value: NCIT C6913
Has_PCDC_GCT_Permissible_Value: NCIT C7009
Has_PCDC_OS_Permissible_Value: NCIT C7134
Has_PCDC_HL_Permissible_Value: NCIT C7258
Has_PCDC_GCT_Permissible_Value: NCIT C8106
Has_PCDC_OS_Permissible_Value: NCIT C8969
Has_PCDC_OS_Permissible_Value: NCIT C8970
Has_PCDC_GCT_Permissible_Value: NCIT C9015
Has_PCDC_HL_Permissible_Value: NCIT C9283
Has_PCDC_GCT_Permissible_Value: NCIT C9309

Quantitative Autoradiography
type: Class
subclass of: BAO_0002527
definition: Autoradiographic analysis performed in accordance with specified guidelines that will result in a defined correspondence between the intensity of the autoradiographic image and the amount of radioactivity present in the sample. This permits assignment of a value to the amount of radioactive material in the object under study.
has exact synonym: Autoradiography, Quantitative
Legacy Concept Name: Autoradiography_Quantitative
UMLS_CUI: C1510991
code: C18639
Preferred_Name: Quantitative Autoradiography
has exact synonym: Quantitative Autoradiography
Semantic_Type: Research Activity
imported from: ncit.owl

Gene Knock-Out Model
type: Class
subclass of: BAO_0010279
UMLS_CUI: C1517490
code: C18803
Semantic_Type: Experimental Model of Disease
has exact synonym: Gene Knock-Out Model
Preferred_Name: Gene Knock-Out Model
Legacy Concept Name: Gene_Knock-Out_Model
definition: Models of human disease produced through gene knockout methods
imported from: ncit.owl

Tissue Slice Technology
type: Class
subclass of: BAO_0002036
definition: A technology used for preclinical research as an alternative to some animal testing. Micrometer-thin slices of various organs are incubated with various experimental compounds for assays involving toxicology, absorption, distribution, and metabolism.
UMLS_CUI: C1519528
code: C19286
Semantic_Type: Research Activity
Preferred_Name: Tissue Slice Technology
has exact synonym: Tissue Slice Technology
Legacy Concept Name: Tissue_Slice_Technology
imported from: ncit.owl

Migration Assay
type: Class
subclass of: BAO_0000015
definition: An in vitro assay in which cultured cells are monitored and analyzed for their ability to move into an acellular area of a culture material.
UMLS_CUI: C1513300
code: C19425
has exact synonym: Cell Migration Assay
Semantic_Type: Laboratory Procedure
Preferred_Name: Migration Assay
has exact synonym: Migration Assay
has exact synonym: Migration Assays
Legacy Concept Name: Migration_Assays
imported from: ncit.owl

Xenograft Model
type: Class
subclass of: BAO_0010279
definition: An experimental system in which (usually) human tumor cells are transplanted into immunocompromised mice that do not reject human cells; cells may be implanted under the skin or into the organ type in which the tumor originated. These model systems may be used for drug development and studies of molecular biological mechanisms of cancer.
UMLS_CUI: C1520166
code: C19812
Semantic_Type: Experimental Model of Disease
Preferred_Name: Xenograft Model
has exact synonym: Xenograft Model
Legacy Concept Name: Xenograft_Model
imported from: ncit.owl

Affinity
type: Class
subclass of: BAO_0002128
Preferred_Name: Affinity
Legacy Concept Name: Affinity
has exact synonym: Affinity
UMLS_CUI: C1510827
code: C20604
ALT_DEFINITION: In chemistry and biology, the strength of the attaction between two substances, such as two chemicals, or an antigen and an antibody.
Semantic_Type: Qualitative Concept
definition: The strength of noncovalent chemical binding between two substances as measured by the dissociation constant of the complex.
has exact synonym: affinity
imported from: ncit.owl

Partition Coefficient
type: Class
subclass of: BAO_0000179
definition: A constant symbolizing the ratio of a dissolved substance in a two-phase system. (from EPA Terminology Reference System)
UMLS_CUI: C1518903
code: C20610
Preferred_Name: Partition Coefficient
has exact synonym: Partition Coefficient
Legacy Concept Name: Partition_Coefficient
Semantic_Type: Quantitative Concept
imported from: ncit.owl

Bleeding Time
type: Class
subclass of: BAO_0002114
ALT_DEFINITION: A measurement of the time from the start to cessation of an induced bleed.
has exact synonym: BLEEDT
Preferred_Name: Bleeding Time
has exact synonym: Bleeding Time
UMLS_CUI: C0005729
code: C89775
Contributing_Source: CDISC
has exact synonym: Clotting Time Homeostasis
Semantic_Type: Laboratory Procedure
definition: The amount of time it take for a cessation of bleeding. It is a measurement of the ability of capillaries and platelets to interact to form a blood clot.
in subset: NCIT C61410
in subset: NCIT C65047
in subset: NCIT C66830
in subset: NCIT C67154
in subset: NCIT C77526
imported from: ncit.owl