imported from
type: AnnotationProperty

definition
type: AnnotationProperty

database_cross_reference
type: AnnotationProperty

has_related_synonym
type: AnnotationProperty

has_obo_namespace
type: AnnotationProperty

has_exact_synonym
type: AnnotationProperty

has_alternative_id
type: AnnotationProperty

in_subset
type: AnnotationProperty

EC 5.4.99.7 (lanosterol synthase) inhibitor
type: Class
subclass of: EC 5.4.99.* (intramolecular transferase transferring other groups) inhibitor
definition: An EC 5.4.99.* (intramolecular transferase transferring other groups) inhibitor that interferes with the action of lanosterol synthase (EC 5.4.99.7).
id: CHEBI:101086
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 5.4.99.* (intramolecular transferase transferring other groups) inhibitor
type: Class
subclass of: EC 5.4.* (intramolecular transferase) inhibitor
definition: An EC 5.4.* (intramolecular transferase) inhibitor that interferes with the activity of any intramolecular transferase transferring other groups (EC 5.4.99.*).
id: CHEBI:101090
has_related_synonym: EC 5.4.99.* (intramolecular transferase transferring other groups) inhibitors
has_related_synonym: EC 5.4.99.* inhibitor
has_related_synonym: EC 5.4.99.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of intramolecular transferase transferring other groups
has_related_synonym: inhibitors of intramolecular transferase transferring other groups
has_related_synonym: intramolecular transferase transferring other groups inhibitor
has_related_synonym: intramolecular transferase transferring other groups inhibitors
in_subset: 3 STAR
imported from: chebi.owl

zidovudine
type: Class
subclass of: molecular entity
charge: 0
monoisotopicmass: 267.09675
mass: 267.24130
has_exact_synonym: 3'-azido-3'-deoxythymidine
definition: A pyrimidine 2',3'-dideoxyribonucleoside compound having a 3'-azido substituent and thymine as the nucleobase.
has_related_synonym: AZT
has_related_synonym: Azidothymidine
database_cross_reference: Beilstein:763034
formula: C10H13N5O4
database_cross_reference: CAS:30516-87-1
id: CHEBI:10110
has_alternative_id: CHEBI:619601
smiles: Cc1cn([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)c(=O)[nH]c1=O
database_cross_reference: DrugBank:DB00495
database_cross_reference: Drug_Central:2861
inchikey: HBOMLICNUCNMMY-XLPZGREQSA-N
inchi: InChI=1S/C10H13N5O4/c1-5-3-15(10(18)12-9(5)17)8-2-6(13-14-11)7(4-16)19-8/h3,6-8,16H,2,4H2,1H3,(H,12,17,18)/t6-,7+,8+/m0/s1
database_cross_reference: KEGG:C07210
database_cross_reference: KEGG:D00413
database_cross_reference: LINCS:LSM-5806
database_cross_reference: MetaCyc:CPD-15110
database_cross_reference: PDBeChem:AZZ
database_cross_reference: PMID:19112024
database_cross_reference: PMID:26859826
database_cross_reference: PMID:29438107
database_cross_reference: PMID:9203666
database_cross_reference: Patent:US4724232
has_related_synonym: Retrovir
database_cross_reference: Wikipedia:Zidovudine
has_related_synonym: Zidovudin
has_related_synonym: Zidovudinum
has_obo_namespace: chebi_ontology
has_related_synonym: zidovudine
in_subset: 3 STAR
imported from: chebi.owl

EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitor
type: Class
subclass of: EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor
definition: An EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor that interferes with the action of hypoxia-inducible factor-proline dioxygenase (EC 1.14.11.29).
id: CHEBI:102248
has_related_synonym: EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitors
has_related_synonym: EC 1.14.11.29 inhibitor
has_related_synonym: EC 1.14.11.29 inhibitors
has_related_synonym: HIF hydroxylase inhibitor
has_related_synonym: HIF hydroxylase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: hypoxia-inducible factor-L-proline, 2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) inhibitor
has_related_synonym: hypoxia-inducible factor-L-proline, 2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) inhibitors
has_related_synonym: prolyl 4-hydroxylase inhibitor
has_related_synonym: prolyl 4-hydroxylase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.6.1.40 [(R)-3-amino-2-methylpropionate--pyruvate transaminase] inhibitor
type: Class
subclass of: EC 2.6.1.* (transaminase) inhibitor
has_related_synonym: (R)-3-amino-2-methylpropanoate:pyruvate aminotransferase inhibitor
has_related_synonym: (R)-3-amino-2-methylpropanoate:pyruvate aminotransferase inhibitors
has_related_synonym: (R)-3-amino-2-methylpropionate transaminase inhibitor
has_related_synonym: (R)-3-amino-2-methylpropionate transaminase inhibitors
has_related_synonym: (R)-3-amino-2-methylpropionate--pyruvate aminotransferase inhibitor
has_related_synonym: (R)-3-amino-2-methylpropionate--pyruvate aminotransferase inhibitors
definition: An EC 2.6.1.* (transaminase) inhibitor that interferes with the action of (R)-3-amino-2-methylpropionate--pyruvate transaminase (EC 2.6.1.40).
id: CHEBI:102368
has_related_synonym: D-3-aminoisobutyrate--pyruvate aminotransferase inhibitor
has_related_synonym: D-3-aminoisobutyrate--pyruvate aminotransferase inhibitors
has_related_synonym: D-3-aminoisobutyrate--pyruvate transaminase inhibitor
has_related_synonym: D-3-aminoisobutyrate--pyruvate transaminase inhibitors
has_related_synonym: D-3-aminoisobutyrate-pyruvate aminotransferase inhibitor
has_related_synonym: D-3-aminoisobutyrate-pyruvate aminotransferase inhibitors
has_related_synonym: D-3-aminoisobutyrate-pyruvate transaminase inhibitor
has_related_synonym: D-3-aminoisobutyrate-pyruvate transaminase inhibitors
has_related_synonym: D-AIBAT inhibitor
has_related_synonym: D-AIBAT inhibitors
has_related_synonym: D-beta-aminoisobutyrate:pyruvate aminotransferase inhibitor
has_related_synonym: D-beta-aminoisobutyrate:pyruvate aminotransferase inhibitors
has_related_synonym: EC 2.6.1.40 [(R)-3-amino-2-methylpropionate--pyruvate transaminase] inhibitors
has_related_synonym: EC 2.6.1.40 inhibitor
has_related_synonym: EC 2.6.1.40 inhibitors
database_cross_reference: Wikipedia:(R)-3-amino-2-methylpropionate-pyruvate_transaminase
has_related_synonym: beta-aminoisobutyrate--pyruvate aminotransferase inhibitor
has_related_synonym: beta-aminoisobutyrate--pyruvate aminotransferase inhibitors
has_related_synonym: beta-aminoisobutyrate--pyruvate transaminase inhibitor
has_related_synonym: beta-aminoisobutyrate--pyruvate transaminase inhibitors
has_related_synonym: beta-aminoisobutyrate-pyruvate aminotransferase inhibitor
has_related_synonym: beta-aminoisobutyrate-pyruvate aminotransferase inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 2.1.1.8 (histamine N-methyltransferase) inhibitor
type: Class
subclass of: EC 2.1.1.* (methyltransferases) inhibitor
definition: An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of histamine N-methyltransferase (EC 2.1.1.8).
id: CHEBI:110725
has_related_synonym: EC 2.1.1.8 (histamine N-methyltransferase) inhibitors
has_related_synonym: EC 2.1.1.8 inhibitor
has_related_synonym: EC 2.1.1.8 inhibitors
has_related_synonym: S-adenosyl-L-methionine:histamine N-tele-methyltransferase inhibitor
has_related_synonym: S-adenosyl-L-methionine:histamine N-tele-methyltransferase inhibitors
has_related_synonym: S-adenosylmethionine-histamine N-methyltransferase inhibitor
has_related_synonym: S-adenosylmethionine-histamine N-methyltransferase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: histamine 1-methyltransferase inhibitor
has_related_synonym: histamine 1-methyltransferase inhibitors
has_related_synonym: histamine methyltransferase inhibitor
has_related_synonym: histamine methyltransferase inhibitors
has_related_synonym: histamine-methylating enzyme inhibitor
has_related_synonym: histamine-methylating enzyme inhibitors
has_related_synonym: imidazolemethyltransferase inhibitor
has_related_synonym: imidazolemethyltransferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

calmodulin antagonist
type: Class
subclass of: antagonist
definition: An antagonist that interferes with the action of the calcium-binding messenger protein calmodulin.
id: CHEBI:130181
database_cross_reference: PMID:26717596
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

IP3 receptor antagonist
type: Class
subclass of: antagonist
definition: An antagonist that binds to and deactivates IP3 receptors.
id: CHEBI:131186
has_related_synonym: D-myo-inositol 1,4,5-trisphosphate receptor antagonist
has_related_synonym: D-myo-inositol 1,4,5-trisphosphate receptor antagonists
has_related_synonym: IP3 antagonist
has_related_synonym: IP3 antagonists
has_related_synonym: IP3 receptor antagonists
has_related_synonym: InsP3R antagonist
has_related_synonym: InsP3R antagonists
database_cross_reference: Wikipedia:Inositol_trisphosphate_receptor
has_obo_namespace: chebi_ontology
has_related_synonym: inositol trisphosphate receptor antagonist
has_related_synonym: inositol trisphosphate receptor antagonists
in_subset: 3 STAR
imported from: chebi.owl

adenosine A2B receptor agonist
type: Class
subclass of: adenosine receptor agonist
has_related_synonym: A2B agonist
has_related_synonym: A2B agonists
has_related_synonym: A2B receptor agonist
has_related_synonym: A2B receptor agonists
definition: An agonist at the A2B receptor.
id: CHEBI:131359
has_related_synonym: adenosine A2B receptor agonists
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

Wnt signalling activator
type: Class
subclass of: activator
definition: A substance that activates any of the Wnt signalling pathway, a group of signal transduction pathways made of proteins that pass signals from outside of a cell through cell surface receptors to the inside of the cell.
id: CHEBI:131492
database_cross_reference: Wikipedia:Wnt_signaling_pathway
has_related_synonym: Wnt signaling activator
has_related_synonym: Wnt signaling activators
has_related_synonym: Wnt signalling activators
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

formyl peptide receptor agonist
type: Class
subclass of: agonist
definition: An agonist that binds to and activates formyl peptide receptors.
id: CHEBI:131495
has_related_synonym: FPR agonist
has_related_synonym: FPR agonists
database_cross_reference: Wikipedia:Formyl_peptide_receptor
has_obo_namespace: chebi_ontology
has_related_synonym: formyl peptide receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

EC 1.14.99.66 (lysine-specific histone demethylase 1A) inhibitor
type: Class
subclass of: EC 1.14.99.* (miscellaneous oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor
has_related_synonym: AOF2 inhibitor
has_related_synonym: AOF2 inhibitors
definition: An EC 1.14.99.* (miscellaneous oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of lysine-specific histone demethylase 1A (EC 1.14.99.66).
has_related_synonym: BHC110 inhibitor
has_related_synonym: BHC110 inhibitors
id: CHEBI:131509
has_related_synonym: CPRF inhibitor
has_related_synonym: CPRF inhibitors
has_related_synonym: EC 1.14.99.66 (lysine-specific histone demethylase 1A) inhibitors
has_related_synonym: EC 1.14.99.66 inhibitor
has_related_synonym: EC 1.14.99.66 inhibitors
has_related_synonym: KDM1A inhibitor
has_related_synonym: KDM1A inhibitors
has_related_synonym: KIAA0601 inhibitor
has_related_synonym: KIAA0601 inhibitors
has_related_synonym: LSD1 inhibitor
has_related_synonym: LSD1 inhibitors
database_cross_reference: Wikipedia:KDM1A
has_related_synonym: [histone H3]-dimethyl-L-lysine(4)FAD-dependent demethylase 1A inhibitor
has_related_synonym: [histone H3]-dimethyl-L-lysine(4)FAD-dependent demethylase 1A inhibitors
has_related_synonym: amine oxidase (flavin containing) domain 2 inhibitor
has_related_synonym: amine oxidase (flavin containing) domain 2 inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: lysine (K)-specific demethylase 1A inhibitor
has_related_synonym: lysine (K)-specific demethylase 1A inhibitors
has_related_synonym: lysine demethylase 1A inhibitor
has_related_synonym: lysine demethylase 1A inhibitors
has_related_synonym: lysine-specific demethylase 1A inhibitor
has_related_synonym: lysine-specific demethylase 1A inhibitors
has_related_synonym: lysine-specific histone demethylase 1A inhibitor
has_related_synonym: lysine-specific histone demethylase 1A inhibitors
in_subset: 3 STAR
imported from: chebi.owl

hyaluronic acid synthesis inhibitor
type: Class
subclass of: inhibitor
definition: Any compound that inhibits one or more steps in the pathway leading to the synthesis of hyaluronic acid.
id: CHEBI:131561
has_related_synonym: HA inhibitor
has_related_synonym: HA inhibitors
has_related_synonym: HA synthesis inhibitor
has_related_synonym: HA synthesis inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: hyaluronic acid inhibitor
has_related_synonym: hyaluronic acid inhibitors
has_related_synonym: hyaluronic acid synthesis inhibitors
in_subset: 3 STAR
imported from: chebi.owl

Mycoplasma genitalium metabolite
type: Class
subclass of: bacterial metabolite
definition: Any bacterial metabolite produced during a metabolic reaction in Mycoplasma genitalium.
id: CHEBI:131604
has_related_synonym: Mycoplasma genitalium metabolites
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

teichoic acid biosynthesis inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
definition: Any compound that inhibits the biosynthesis of teichoic acid.
id: CHEBI:131611
has_related_synonym: TarO inhibitor
has_related_synonym: TarO inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: teichoic acid biosynthesis inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor
type: Class
subclass of: DNA polymerase inhibitor
definition: A DNA polymerase inhibitor that interferes with the action of a DNA-directed DNA polymerase (EC 2.7.7.7).
id: CHEBI:131699
has_related_synonym: DNA duplicase inhibitor
has_related_synonym: DNA duplicase inhibitors
has_related_synonym: DNA nucleotidyltransferase (DNA-directed) inhibitor
has_related_synonym: DNA nucleotidyltransferase (DNA-directed) inhibitors
has_related_synonym: DNA nucleotidyltransferase inhibitor
has_related_synonym: DNA nucleotidyltransferase inhibitors
has_related_synonym: DNA polymerase I inhibitor
has_related_synonym: DNA polymerase I inhibitors
has_related_synonym: DNA polymerase II inhibitor
has_related_synonym: DNA polymerase II inhibitors
has_related_synonym: DNA polymerase III inhibitor
has_related_synonym: DNA polymerase III inhibitors
has_related_synonym: DNA polymerase alpha inhibitor
has_related_synonym: DNA polymerase alpha inhibitors
has_related_synonym: DNA polymerase beta inhibitor
has_related_synonym: DNA polymerase beta inhibitors
has_related_synonym: DNA polymerase gamma inhibitor
has_related_synonym: DNA polymerase gamma inhibitors
has_related_synonym: DNA polymerase inhibitor
has_related_synonym: DNA polymerase inhibitors
has_related_synonym: DNA replicase inhibitor
has_related_synonym: DNA replicase inhibitors
has_related_synonym: DNA-dependent DNA polymerase inhibitor
has_related_synonym: DNA-dependent DNA polymerase inhibitors
has_related_synonym: DNA-directed DNA polymerase (EC 2.7.7.7) inhibitor
has_related_synonym: DNA-directed DNA polymerase (EC 2.7.7.7) inhibitors
has_related_synonym: EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitors
has_related_synonym: EC 2.7.7.7 inhibitor
has_related_synonym: EC 2.7.7.7 inhibitors
has_related_synonym: Klenow fragment inhibitor
has_related_synonym: Klenow fragment inhibitors
has_related_synonym: Taq DNA polymerase inhibitor
has_related_synonym: Taq DNA polymerase inhibitors
has_related_synonym: Taq Pol I inhibitor
has_related_synonym: Taq Pol I inhibitors
has_related_synonym: Tca DNA polymerase inhibitor
has_related_synonym: Tca DNA polymerase inhibitors
database_cross_reference: Wikipedia:DNA_polymerase
has_obo_namespace: chebi_ontology
has_related_synonym: deoxynucleate polymerase inhibitor
has_related_synonym: deoxynucleate polymerase inhibitors
has_related_synonym: deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) inhibitor
has_related_synonym: deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) inhibitors
has_related_synonym: deoxyribonucleate nucleotidyltransferase inhibitor
has_related_synonym: deoxyribonucleate nucleotidyltransferase inhibitors
has_related_synonym: deoxyribonucleic acid duplicase inhibitor
has_related_synonym: deoxyribonucleic acid duplicase inhibitors
has_related_synonym: deoxyribonucleic acid polymerase inhibitor
has_related_synonym: deoxyribonucleic acid polymerase inhibitors
has_related_synonym: deoxyribonucleic duplicase inhibitor
has_related_synonym: deoxyribonucleic duplicase inhibitors
has_related_synonym: deoxyribonucleic polymerase I inhibitor
has_related_synonym: deoxyribonucleic polymerase I inhibitors
has_related_synonym: deoxyribonucleic polymerase inhibitor
has_related_synonym: deoxyribonucleic polymerase inhibitors
has_related_synonym: duplicase inhibitor
has_related_synonym: duplicase inhibitors
has_related_synonym: sequenase inhibitor
has_related_synonym: sequenase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.11.20 (elongation factor 2 kinase) inhibitor
type: Class
subclass of: EC 2.7.11.* (protein-serine/threonine kinase) inhibitor
has_related_synonym: ATP:[elongation factor 2] phosphotransferase inhibitor
has_related_synonym: ATP:[elongation factor 2] phosphotransferase inhibitors
definition: Any EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of elongation factor 2 kinase (EC 2.7.11.20).
id: CHEBI:131734
has_related_synonym: Ca/CaM-kinase III inhibitor
has_related_synonym: Ca/CaM-kinase III inhibitors
has_related_synonym: CaM kinase III inhibitor
has_related_synonym: CaM kinase III inhibitors
has_related_synonym: EC 2.7.11.20 (elongation factor 2 kinase) inhibitors
has_related_synonym: EC 2.7.11.20 inhibitor
has_related_synonym: EC 2.7.11.20 inhibitors
has_related_synonym: EF2K inhibitor
has_related_synonym: EF2K inhibitors
has_related_synonym: STK19 inhibitor
has_related_synonym: STK19 inhibitors
database_cross_reference: Wikipedia:Elongation_factor_2_kinase
has_related_synonym: calmodulin-dependent protein kinase III inhibitor
has_related_synonym: calmodulin-dependent protein kinase III inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: eEF2 kinase inhibitor
has_related_synonym: eEF2 kinase inhibitors
has_related_synonym: eEF2K inhibitor
has_related_synonym: eEF2K inhibitors
has_related_synonym: elongation factor 2 kinase (EC 2.7.11.20) inhibitor
has_related_synonym: elongation factor 2 kinase (EC 2.7.11.20) inhibitors
has_related_synonym: elongation factor 2 kinase inhibitor
has_related_synonym: elongation factor 2 kinase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor
type: Class
subclass of: EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor
definition: A EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of channel-conductance-controlling ATPase (EC 3.6.3.49, also known as cystic fibrosis conductance regulator, CFCR).
has_related_synonym: ATP phosphohydrolase (channel-conductance-controlling) inhibitor
has_related_synonym: ATP phosphohydrolase (channel-conductance-controlling) inhibitors
has_related_synonym: CFTR inhibitor
has_related_synonym: CFTR inhibitors
id: CHEBI:131770
has_alternative_id: CHEBI:131771
has_related_synonym: EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitors
has_related_synonym: EC 3.6.3.49 inhibitor
has_related_synonym: EC 3.6.3.49 inhibitors
database_cross_reference: Wikipedia:Cystic_fibrosis_transmembrane_conductance_regulator
has_related_synonym: channel-conductance-controlling ATPase (EC 3.6.3.49) inhibitor
has_related_synonym: channel-conductance-controlling ATPase (EC 3.6.3.49) inhibitors
has_related_synonym: channel-conductance-controlling ATPase inhibitor
has_related_synonym: channel-conductance-controlling ATPase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: cystic fibrosis conductance regulator inhibitor
has_related_synonym: cystic fibrosis conductance regulator inhibitors
has_related_synonym: cystic fibrosis transmembrane conductance regulator inhibitor
has_related_synonym: cystic fibrosis transmembrane conductance regulator inhibitors
has_related_synonym: cystic-fibrosis membrane-conductance-regulating protein inhibitor
has_related_synonym: cystic-fibrosis membrane-conductance-regulating protein inhibitors
in_subset: 3 STAR
imported from: chebi.owl

dopamine receptor D2 antagonist
type: Class
subclass of: antagonist
definition: An antagonist that binds to and deactivates the dopamine receptor D2, the main receptor for all antipsychotic drugs.
id: CHEBI:131787
has_related_synonym: D2 receptor antagonist
has_related_synonym: D2R antagonist
database_cross_reference: PMID:23323533
database_cross_reference: Wikipedia:Dopamine_receptor_D2
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

RUNX1 inhibitor
type: Class
subclass of: inhibitor
has_related_synonym: AML1 inhibitor
has_related_synonym: AML1 inhibitors
definition: An inhibitor that interferes with RUNX1 (runt-related transcription factor 1), a transcription factor protein that regulates the differentiation of haematopoietic stem cells into mature blood cells.
has_related_synonym: CBFA2 inhibitor
has_related_synonym: CBFA2 inhibitors
id: CHEBI:131789
has_related_synonym: RUNX1 inhibitors
database_cross_reference: Wikipedia:RUNX1
has_related_synonym: acute myeloid leukemia 1 protein inhibitor
has_related_synonym: acute myeloid leukemia 1 protein inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: core-binding factor subunit alpha-2 inhibitor
has_related_synonym: core-binding factor subunit alpha-2 inhibitors
has_related_synonym: core-binding factor subunit alpha2 inhibitor
has_related_synonym: core-binding factor subunit alpha2 inhibitors
has_related_synonym: runt-related transcription factor 1 inhibitor
has_related_synonym: runt-related transcription factor 1 inhibitors
in_subset: 3 STAR
imported from: chebi.owl

melatonin receptor antagonist
type: Class
subclass of: antagonist
definition: An antagonist that binds to and deactivates melatonin receptors.
id: CHEBI:131790
database_cross_reference: Wikipedia:Melatonin_receptor
has_obo_namespace: chebi_ontology
has_related_synonym: melatonin receptor antagonists
in_subset: 3 STAR
imported from: chebi.owl

HIV-1 Tat inhibitor
type: Class
subclass of: inhibitor
definition: An inhibitor of gene expression of human immunodeficiency virus type 1 (HIV-1) at the transcriptional level through interference with Tat-mediated transactivation.
id: CHEBI:131791
has_related_synonym: HIV-1 Tat antagonist
has_related_synonym: HIV-1 Tat antagonists
has_related_synonym: HIV-1 Tat inhibitors
has_related_synonym: HIV-1 trans-activator of transcription antagonist
has_related_synonym: HIV-1 trans-activator of transcription antagonists
database_cross_reference: PMID:11747436
database_cross_reference: PMID:7650672
database_cross_reference: PMID:8410982
database_cross_reference: PMID:9548739
database_cross_reference: Wikipedia:Tat_(HIV)
has_obo_namespace: chebi_ontology
has_related_synonym: human immunodeficiency virus type 1 Tat antagonist
has_related_synonym: human immunodeficiency virus type 1 Tat antagonists
has_related_synonym: human immunodeficiency virus type 1 Tat inhibitor
has_related_synonym: human immunodeficiency virus type 1 Tat inhibitors
has_related_synonym: human immunodeficiency virus type 1 trans-activator of transcription antagonist
has_related_synonym: human immunodeficiency virus type 1 trans-activator of transcription antagonists
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.11.17 (Ca(2+)/calmodulin-dependent protein kinase) inhibitor
type: Class
subclass of: EC 2.7.11.* (protein-serine/threonine kinase) inhibitor
has_related_synonym: ATP:caldesmon O-phosphotransferase inhibitor
has_related_synonym: ATP:caldesmon O-phosphotransferase inhibitors
has_related_synonym: ATP:protein phosphotransferase ((2+)/calmodulin-dependent) inhibitor
has_related_synonym: ATP:protein phosphotransferase ((2+)/calmodulin-dependent) inhibitors
definition: Any EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of a Ca(2+)/calmodulin-dependent protein kinase (EC 2.7.11.17).
has_related_synonym: CAM PKII inhibitor
has_related_synonym: CAM PKII inhibitors
id: CHEBI:131794
has_related_synonym: Ca(2+)/calmodulin-dependent microtubule-associated protein 2 kinase inhibitor
has_related_synonym: Ca(2+)/calmodulin-dependent microtubule-associated protein 2 kinase inhibitors
has_related_synonym: Ca(2+)/calmodulin-dependent protein kinase (EC 2.7.11.17) inhibitor
has_related_synonym: Ca(2+)/calmodulin-dependent protein kinase (EC 2.7.11.17) inhibitors
has_related_synonym: Ca(2+)/calmodulin-dependent protein kinase 1 inhibitor
has_related_synonym: Ca(2+)/calmodulin-dependent protein kinase 1 inhibitors
has_related_synonym: Ca(2+)/calmodulin-dependent protein kinase II inhibitor
has_related_synonym: Ca(2+)/calmodulin-dependent protein kinase II inhibitors
has_related_synonym: Ca(2+)/calmodulin-dependent protein kinase IV inhibitor
has_related_synonym: Ca(2+)/calmodulin-dependent protein kinase IV inhibitors
has_related_synonym: Ca(2+)/calmodulin-dependent protein kinase inhibitor
has_related_synonym: Ca(2+)/calmodulin-dependent protein kinase inhibitors
has_related_synonym: Ca(2+)/calmodulin-dependent protein kinase kinase beta inhibitor
has_related_synonym: Ca(2+)/calmodulin-dependent protein kinase kinase beta inhibitors
has_related_synonym: Ca(2+)/calmodulin-dependent protein kinase kinase inhibitor
has_related_synonym: Ca(2+)/calmodulin-dependent protein kinase kinase inhibitors
has_related_synonym: CaM kinase II inhibitor
has_related_synonym: CaM kinase II inhibitors
has_related_synonym: CaM kinase inhibitor
has_related_synonym: CaM kinase inhibitors
has_related_synonym: CaM-regulated serine/threonine kinase inhibitor
has_related_synonym: CaM-regulated serine/threonine kinase inhibitors
has_related_synonym: CaMKI inhibitor
has_related_synonym: CaMKI inhibitors
has_related_synonym: CaMKII inhibitor
has_related_synonym: CaMKII inhibitors
has_related_synonym: CaMKIV inhibitor
has_related_synonym: CaMKIV inhibitors
has_related_synonym: CaMKKalpha inhibitor
has_related_synonym: CaMKKalpha inhibitors
has_related_synonym: CaMKKbeta inhibitor
has_related_synonym: CaMKKbeta inhibitors
has_related_synonym: EC 2.7.11.17 (Ca(2+)/calmodulin-dependent protein kinase) inhibitors
has_related_synonym: EC 2.7.11.17 inhibitor
has_related_synonym: EC 2.7.11.17 inhibitors
has_related_synonym: STK20 inhibitor
has_related_synonym: STK20 inhibitors
database_cross_reference: Wikipedia:CAMK
has_related_synonym: caldesmon kinase (phosphorylating) inhibitor
has_related_synonym: caldesmon kinase (phosphorylating) inhibitors
has_related_synonym: caldesmon kinase inhibitor
has_related_synonym: caldesmon kinase inhibitors
has_related_synonym: calmodulin-dependent kinase II inhibitor
has_related_synonym: calmodulin-dependent kinase II inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: microtubule-associated protein 2 kinase inhibitor
has_related_synonym: microtubule-associated protein 2 kinase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

dopamine receptor D1 agonist
type: Class
subclass of: dopamine agonist
definition: A dopamine agonist that binds to and activates the dopamine receptor D1.
id: CHEBI:131795
has_related_synonym: D1 agonist
has_related_synonym: D1 agonists
database_cross_reference: Wikipedia:Dopamine_receptor_D1
has_obo_namespace: chebi_ontology
has_related_synonym: dopamine D1 receptor agonist
has_related_synonym: dopamine D1 receptor agonists
has_related_synonym: dopamine receptor D1 agonists
in_subset: 3 STAR
imported from: chebi.owl

SMO receptor agonist
type: Class
subclass of: agonist
definition: An agonist that enhances the action of smoothened (SMO) receptor.
id: CHEBI:131809
database_cross_reference: PMID:12437772
database_cross_reference: PMID:20439738
has_related_synonym: SMO receptor agonists
database_cross_reference: Wikipedia:Smoothened
has_obo_namespace: chebi_ontology
has_related_synonym: smoothened agonist
has_related_synonym: smoothened agonists
has_related_synonym: smoothened receptor agonist
has_related_synonym: smoothened receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

EC 1.14.11.1 (gamma-butyrobetaine dioxygenase) inhibitor
type: Class
subclass of: EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor
has_related_synonym: 4-trimethylammoniobutanoate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) inhibitor
has_related_synonym: 4-trimethylammoniobutanoate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) inhibitors
definition: An EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor that interferes with the action of gamma-butyrobetaine dioxygenase (EC 1.14.11.1).
has_related_synonym: BBOX inhibitor
has_related_synonym: BBOX inhibitors
id: CHEBI:131844
has_related_synonym: EC 1.14.11.1 (gamma-butyrobetaine dioxygenase) inhibitors
has_related_synonym: EC 1.14.11.1 inhibitor
has_related_synonym: EC 1.14.11.1 inhibitors
database_cross_reference: Wikipedia:Gamma-butyrobetaine_dioxygenase
has_related_synonym: alpha-butyrobetaine hydroxylase inhibitor
has_related_synonym: alpha-butyrobetaine hydroxylase inhibitors
has_related_synonym: butyrobetaine hydroxylase inhibitor
has_related_synonym: butyrobetaine hydroxylase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: gamma-butyrobetaine hydroxylase inhibitor
has_related_synonym: gamma-butyrobetaine hydroxylase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.13.11.11 (tryptophan 2,3-dioxygenase) inhibitor
type: Class
subclass of: EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitor
definition: An EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitor that interferes with the action of tryptophan 2,3-dioxygenase (EC 1.13.11.11).
id: CHEBI:131961
has_related_synonym: EC 1.13.11.11 (tryptophan 2,3-dioxygenase) inhibitors
has_related_synonym: EC 1.13.11.11 inhibitor
has_related_synonym: EC 1.13.11.11 inhibitors
has_related_synonym: L-tryptophan 2,3-dioxygenase inhibitor
has_related_synonym: L-tryptophan 2,3-dioxygenase inhibitors
has_related_synonym: L-tryptophan pyrrolase inhibitor
has_related_synonym: L-tryptophan pyrrolase inhibitors
has_related_synonym: L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing) inhibitor
has_related_synonym: L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing) inhibitors
has_related_synonym: L-tryptophan:oxygen 2,3-oxidoreductase (ring-opening) inhibitor
has_related_synonym: L-tryptophan:oxygen 2,3-oxidoreductase (ring-opening) inhibitors
has_related_synonym: TDO inhibitor
has_related_synonym: TDO inhibitors
database_cross_reference: Wikipedia:Tryptophan_2,3-dioxygenase
has_obo_namespace: chebi_ontology
has_related_synonym: indolamine 2,3-dioxygenase inhibitor
has_related_synonym: indolamine 2,3-dioxygenase inhibitors
has_related_synonym: indoleamine 2,3-dioxygenase inhibitor
has_related_synonym: indoleamine 2,3-dioxygenase inhibitors
has_related_synonym: tryptamin 2,3-dioxygenase inhibitor
has_related_synonym: tryptamin 2,3-dioxygenase inhibitors
has_related_synonym: tryptamine 2,3-dioxygenase inhibitor
has_related_synonym: tryptamine 2,3-dioxygenase inhibitors
has_related_synonym: tryptophan 2,3-dioxygenase (EC 1.13.11.11) inhibitor
has_related_synonym: tryptophan 2,3-dioxygenase (EC 1.13.11.11) inhibitors
has_related_synonym: tryptophan 2,3-dioxygenase inhibitor
has_related_synonym: tryptophan 2,3-dioxygenase inhibitors
has_related_synonym: tryptophan oxygenase inhibitor
has_related_synonym: tryptophan oxygenase inhibitors
has_related_synonym: tryptophan peroxidase inhibitor
has_related_synonym: tryptophan peroxidase inhibitors
has_related_synonym: tryptophan pyrrolase inhibitor
has_related_synonym: tryptophan pyrrolase inhibitors
has_related_synonym: tryptophanase inhibitor
has_related_synonym: tryptophanase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

herbicide safener
type: Class
subclass of: agrochemical
definition: A compound used with herbicides that reduces the effect of the herbicide on crop plants or otherwise improves the selectivity of the herbicide for weed species over the crop plant.
id: CHEBI:132272
database_cross_reference: PMID:12222792
database_cross_reference: PMID:23564986
database_cross_reference: Wikipedia:Herbicide_safener
has_obo_namespace: chebi_ontology
has_related_synonym: herbicide safeners
in_subset: 3 STAR
imported from: chebi.owl

EC 1.14.11.2 (procollagen-proline dioxygenase) inhibitor
type: Class
subclass of: EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor
definition: An EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor that interferes with the action of procollagen-proline dioxygenase (EC 1.14.11.2).
id: CHEBI:132365
has_related_synonym: EC 1.14.11.2 (procollagen-proline dioxygenase) inhibitors
has_related_synonym: EC 1.14.11.2 inhibitor
has_related_synonym: EC 1.14.11.2 inhibitors
database_cross_reference: Wikipedia:Procollagen-proline_dioxygenase
has_obo_namespace: chebi_ontology
has_related_synonym: collagen proline hydroxylase inhibitor
has_related_synonym: collagen proline hydroxylase inhibitors
has_related_synonym: hydroxylase, collagen proline inhibitor
has_related_synonym: hydroxylase, collagen proline inhibitors
has_related_synonym: peptidyl proline hydroxylase inhibitor
has_related_synonym: peptidyl proline hydroxylase inhibitors
has_related_synonym: procollagen-L-proline,2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) inhibitor
has_related_synonym: procollagen-L-proline,2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) inhibitors
has_related_synonym: procollagen-proline 4-dioxygenase inhibitor
has_related_synonym: procollagen-proline 4-dioxygenase inhibitors
has_related_synonym: procollagen-proline dioxygenase (EC 1.14.11.2) inhibitor
has_related_synonym: procollagen-proline dioxygenase (EC 1.14.11.2) inhibitors
has_related_synonym: procollagen-proline dioxygenase inhibitor
has_related_synonym: procollagen-proline dioxygenase inhibitors
has_related_synonym: procollagen-proline,2-oxoglutarate-4-dioxygenase inhibitor
has_related_synonym: procollagen-proline,2-oxoglutarate-4-dioxygenase inhibitors
has_related_synonym: proline hydroxylase inhibitor
has_related_synonym: proline hydroxylase inhibitors
has_related_synonym: proline protocollagen hydroxylase inhibitor
has_related_synonym: proline protocollagen hydroxylase inhibitors
has_related_synonym: proline, 2-oxoglutarate dioxygenase inhibitor
has_related_synonym: proline, 2-oxoglutarate dioxygenase inhibitors
has_related_synonym: proline,2-oxoglutarate 4-dioxygenase inhibitor
has_related_synonym: proline,2-oxoglutarate 4-dioxygenase inhibitors
has_related_synonym: prolyl 4-hydroxylase inhibitor
has_related_synonym: prolyl 4-hydroxylase inhibitors
has_related_synonym: prolyl hydroxylase inhibitor
has_related_synonym: prolyl hydroxylase inhibitors
has_related_synonym: prolyl-glycyl-peptide, 2-oxoglutarate:oxygen oxidoreductase, 4-hydroxylating inhibitor
has_related_synonym: prolyl-glycyl-peptide, 2-oxoglutarate:oxygen oxidoreductase, 4-hydroxylating inhibitors
has_related_synonym: prolylprotocollagen dioxygenase inhibitor
has_related_synonym: prolylprotocollagen dioxygenase inhibitors
has_related_synonym: prolylprotocollagen hydroxylase inhibitor
has_related_synonym: prolylprotocollagen hydroxylase inhibitors
has_related_synonym: protocollagen hydroxylase inhibitor
has_related_synonym: protocollagen hydroxylase inhibitors
has_related_synonym: protocollagen proline 4-hydroxylase inhibitor
has_related_synonym: protocollagen proline 4-hydroxylase inhibitors
has_related_synonym: protocollagen proline dioxygenase inhibitor
has_related_synonym: protocollagen proline dioxygenase inhibitors
has_related_synonym: protocollagen proline hydroxylase inhibitor
has_related_synonym: protocollagen proline hydroxylase inhibitors
has_related_synonym: protocollagen prolyl hydroxylase inhibitor
has_related_synonym: protocollagen prolyl hydroxylase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.2.1.23 (beta-galactosidase) inhibitor
type: Class
subclass of: EC 3.2.1.* (glycosidase) inhibitor
definition: An EC 3.2.1.* (glycosidase) inhibitor that interferes with the action of beta-galactosidase (EC 3.2.1.23).
id: CHEBI:132518
has_related_synonym: EC 3.2.1.23 (beta-galactosidase) inhibitors
has_related_synonym: EC 3.2.1.23 inhibitor
has_related_synonym: EC 3.2.1.23 inhibitors
has_related_synonym: S 2107 inhibitor
has_related_synonym: S 2107 inhibitors
has_related_synonym: beta-D-galactanase inhibitor
has_related_synonym: beta-D-galactanase inhibitors
has_related_synonym: beta-D-galactoside galactohydrolase inhibitor
has_related_synonym: beta-D-galactoside galactohydrolase inhibitors
has_related_synonym: beta-D-lactosidase inhibitor
has_related_synonym: beta-D-lactosidase inhibitors
has_related_synonym: beta-lactosidase inhibitor
has_related_synonym: beta-lactosidase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: exo-(1->4)-beta-D-galactanase inhibitor
has_related_synonym: exo-(1->4)-beta-D-galactanase inhibitors
has_related_synonym: hydrolact inhibitor
has_related_synonym: hydrolact inhibitors
has_related_synonym: lactase inhibitor
has_related_synonym: lactase inhibitors
has_related_synonym: lactozym inhibitor
has_related_synonym: lactozym inhibitors
has_related_synonym: maxilact inhibitor
has_related_synonym: maxilact inhibitors
has_related_synonym: oryzatym inhibitor
has_related_synonym: oryzatym inhibitors
has_related_synonym: sumiklat inhibitor
has_related_synonym: sumiklat inhibitors
has_related_synonym: trilactase inhibitor
has_related_synonym: trilactase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

TRPM4 channel inhibitor
type: Class
subclass of: inhibitor
definition: An inhibitor of transient receptor potential cation channel subfamily M member 4.
id: CHEBI:132608
has_related_synonym: TRPM4 channel inhibitors
has_related_synonym: Transient receptor potential cation channel subfamily M member 4 inhibitor
has_related_synonym: Transient receptor potential cation channel subfamily M member 4 inhibitors
database_cross_reference: Wikipedia:TRPM4
has_obo_namespace: chebi_ontology
has_related_synonym: melastatin 4 inhibitor
has_related_synonym: melastatin 4 inhibitors
in_subset: 3 STAR
imported from: chebi.owl

xenoantigen
type: Class
subclass of: antigen
definition: An antigen that is found in more than one species.
id: CHEBI:132710
database_cross_reference: PMID:25605448
database_cross_reference: PMID:26572140
database_cross_reference: PMID:26978574
database_cross_reference: PMID:27154491
database_cross_reference: PMID:27379553
has_obo_namespace: chebi_ontology
has_related_synonym: xenoantigens
in_subset: 3 STAR
imported from: chebi.owl

bleaching agent
type: Class
subclass of: reagent
definition: A reagent that lightens or whitens a substrate through chemical reaction. Bleaching reactions usually involve oxidative or reductive processes that degrade colour systems. Bleaching can occur by destroying one or more of the double bonds in the conjugated chain, by cleaving the conjugated chain, or by oxidation of one of the other moieties in the conjugated chain. Their reactivity results in many bleaches having strong bactericidal, disinfecting, and sterilising properties.
id: CHEBI:132717
database_cross_reference: Wikipedia:Bleach
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 3.6.5.* (hydrolases acting on GTP; involved in cellular and subcellular movement) inhibitor
type: Class
subclass of: EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor
definition: Any EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor that interferes with the action of any such enzyme acting on GTP that is involved in cellular and subcellular movement (EC 3.6.5.*).
id: CHEBI:132771
has_related_synonym: EC 3.6.5.* (hydrolases acting on GTP; involved in cellular and subcellular movement) inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 3.6.5.5 (dynamin GTPase) inhibitor
type: Class
subclass of: EC 3.6.5.* (hydrolases acting on GTP; involved in cellular and subcellular movement) inhibitor
definition: An EC 3.6.5.* (hydrolases acting on GTP; involved in cellular and subcellular movement) inhibitor that interferes with the action of dynamin GTPase (EC 3.6.5.5).
id: CHEBI:132772
has_related_synonym: EC 3.6.5.5 (dynamin GTPase) inhibitors
has_related_synonym: EC 3.6.5.5 inhibitor
has_related_synonym: EC 3.6.5.5 inhibitors
has_related_synonym: GTP phosphohydrolase (vesicle-releasing) inhibitor
has_related_synonym: GTP phosphohydrolase (vesicle-releasing) inhibitors
database_cross_reference: Wikipedia:Dynamin
has_obo_namespace: chebi_ontology
has_related_synonym: dynamin GTPase (EC 3.6.5.5) inhibitor
has_related_synonym: dynamin GTPase (EC 3.6.5.5) inhibitors
has_related_synonym: dynamin GTPase inhibitor
has_related_synonym: dynamin GTPase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

farnesoid X receptor agonist
type: Class
subclass of: agonist
definition: An agonist that binds to and activates farnesoid X receptors
has_related_synonym: BAR agonist
has_related_synonym: BAR agonists
id: CHEBI:132972
has_related_synonym: FXR agonist
has_related_synonym: FXR agonists
database_cross_reference: Wikipedia:Farnesoid_X_receptor
has_related_synonym: bile acid receptor agonist
has_related_synonym: bile acid receptor agonists
has_obo_namespace: chebi_ontology
has_related_synonym: farnesoid X receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

radiosensitizing agent
type: Class
subclass of: drug
definition: A drug that makes increases the sensitivity of tumour cells to radiation therapy.
id: CHEBI:132992
database_cross_reference: PMID:12520460
database_cross_reference: Wikipedia:Radiosensitizer
has_obo_namespace: chebi_ontology
has_related_synonym: radiosensitiser
has_related_synonym: radiosensitisers
has_related_synonym: radiosensitising agent
has_related_synonym: radiosensitising agents
has_related_synonym: radiosensitizer
has_related_synonym: radiosensitizers
has_related_synonym: radiosensitizing agents
in_subset: 3 STAR
imported from: chebi.owl

5-hydroxytryptamine 2A receptor inverse agonist
type: Class
subclass of: inverse agonist
has_related_synonym: 5-hydroxytryptamine (2A) receptor inverse agonist
has_related_synonym: 5-hydroxytryptamine (2A) receptor inverse agonists
has_related_synonym: 5-hydroxytryptamine 2A receptor inverse agonists
has_related_synonym: 5HT(2A) inverse agonist
has_related_synonym: 5HT(2A) inverse agonists
has_related_synonym: 5HT2A inverse agonists
has_related_synonym: 5HT2Ainverse agonist
definition: An inverse agonist that binds to the same receptor as a 5-hydroxytryptamine 2A receptor agonist, but which induces a pharmacological response opposite to that agonist.
id: CHEBI:133016
database_cross_reference: Wikipedia:5-HT2A_receptor
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

B-cell lymphoma 2 inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
definition: Any inhibitor of B-cell lymphoma 2 protein.
has_related_synonym: B-cell lymphoma 2 inhibitors
has_related_synonym: Bcl-2 inhibitor
has_related_synonym: Bcl-2 inhibitors
id: CHEBI:133022
database_cross_reference: Wikipedia:Bcl-2
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

lymphocyte function-associated antigen-1 antagonist
type: Class
subclass of: antagonist
definition: Any antagonist of lymphocyte function-associated antigen-1
id: CHEBI:133024
has_related_synonym: LFA-1 antagonist
has_related_synonym: LFA-1 antagonists
database_cross_reference: Wikipedia:Lymphocyte_function-associated_antigen_1
has_obo_namespace: chebi_ontology
has_related_synonym: lymphocyte function-associated antigen-1 antagonists
in_subset: 3 STAR
imported from: chebi.owl

chemical hybridisation agent
type: Class
subclass of: plant growth regulator
definition: A plant growth regulator that produces male sterility in plants by preventing pollen development, pollen shed, or pollen viability. This makes the plant adaptable to hybridization without the need for laborious hand pollination.
id: CHEBI:133106
has_obo_namespace: chebi_ontology
has_related_synonym: chemical hybridisation agents
has_related_synonym: chemical hybridization agent
has_related_synonym: chemical hybridization agents
in_subset: 3 STAR
imported from: chebi.owl

fatty acid oxidation inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
definition: A compound that inhibits the oxidation of any fatty acid.
id: CHEBI:133190
database_cross_reference: Wikipedia:Fatty_acid_oxidation_inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: fatty acid oxidation inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.4.1.17 (glucuronosyltransferase) inhibitor
type: Class
subclass of: EC 2.4.1.* (hexosyltransferase) inhibitor
has_related_synonym: 1-naphthol glucuronyltransferase inhibitor
has_related_synonym: 1-naphthol glucuronyltransferase inhibitors
has_related_synonym: 1-naphthol-UDP-glucuronosyltransferase inhibitor
has_related_synonym: 1-naphthol-UDP-glucuronosyltransferase inhibitors
has_related_synonym: 17-OH steroid UDPGT inhibitor
has_related_synonym: 17-OH steroid UDPGT inhibitors
has_related_synonym: 17beta-hydroxysteroid UDP-glucuronosyltransferase inhibitor
has_related_synonym: 17beta-hydroxysteroid UDP-glucuronosyltransferase inhibitors
has_related_synonym: 3-OH androgenic UDPGT inhibitor
has_related_synonym: 3-OH androgenic UDPGT inhibitors
has_related_synonym: 3alpha-hydroxysteroid UDP-glucuronosyltransferase inhibitor
has_related_synonym: 3alpha-hydroxysteroid UDP-glucuronosyltransferase inhibitors
has_related_synonym: 4-hydroxybiphenyl UDP-glucuronosyltransferase inhibitor
has_related_synonym: 4-hydroxybiphenyl UDP-glucuronosyltransferase inhibitors
definition: A EC 2.4.1.* (hexosyltransferase) inhibitor that inhibits the action of glucuronosyltransferase (EC 2.4.1.17).
id: CHEBI:133811
has_related_synonym: EC 2.4.1.17 (glucuronosyltransferase) inhibitors
has_related_synonym: EC 2.4.1.17 inhibitor
has_related_synonym: EC 2.4.1.17 inhibitors
has_related_synonym: UDP glucuronic acid transferase inhibitors
has_related_synonym: UDP glucuronosyltransferase inhibitor
has_related_synonym: UDP glucuronosyltransferase inhibitors
has_related_synonym: UDP glucuronyltransferase inhibitor
has_related_synonym: UDP glucuronyltransferase inhibitors
has_related_synonym: UDP-alpha-D-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific; conformation-inverting) inhibitor
has_related_synonym: UDP-alpha-D-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific; conformation-inverting) inhibitors
has_related_synonym: UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) inhibitor
has_related_synonym: UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) inhibitors
has_related_synonym: UDP-glucuronyltransferase inhibitor
has_related_synonym: UDP-glucuronyltransferase inhibitors
has_related_synonym: UDPGA transferase inhibitor
has_related_synonym: UDPGA transferase inhibitors
has_related_synonym: UDPGA-glucuronyltransferase inhibitor
has_related_synonym: UDPGA-glucuronyltransferase inhibitors
has_related_synonym: UDPGT inhibitor
has_related_synonym: UDPGT inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: glucuronosyltransferase inhibitor
has_related_synonym: glucuronosyltransferase inhibitors
has_related_synonym: uridine 5'-diphosphoglucuronyltransferase inhibitor
has_related_synonym: uridine 5'-diphosphoglucuronyltransferase inhibitors
has_related_synonym: uridine diphosphate glucuronyltransferase inhibitor
has_related_synonym: uridine diphosphate glucuronyltransferase inhibitors
has_related_synonym: uridine diphosphoglucuronosyltransferase inhibitor
has_related_synonym: uridine diphosphoglucuronosyltransferase inhibitors
has_related_synonym: uridine diphosphoglucuronyltransferase inhibitor
has_related_synonym: uridine diphosphoglucuronyltransferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

neuropeptide Y receptor antagonist
type: Class
subclass of: antagonist
definition: An antagonist that binds to and deactivates neuropeptide Y receptors.
id: CHEBI:133878
database_cross_reference: Wikipedia:Neuropeptide_Y_receptor
has_obo_namespace: chebi_ontology
has_related_synonym: neuropeptide Y receptor antagonists
in_subset: 3 STAR
imported from: chebi.owl

salt-inducible kinase 2 inhibitor
type: Class
subclass of: protein kinase inhibitor
definition: Any protein kinase inhibitor that interferes with the action of salt-inducible kinase 2.
id: CHEBI:133891
has_related_synonym: SIK2 inhibitor
has_related_synonym: SIK2 inhibitors
has_related_synonym: SNF1LK2 inhibitor
has_related_synonym: SNF1LK2 inhibitors
database_cross_reference: Wikipedia:SNF1LK2
has_obo_namespace: chebi_ontology
has_related_synonym: salt-inducible kinase 2 inhibitors
has_related_synonym: serine/threonine-protein kinase SIK2 inhibitor
in_subset: 3 STAR
imported from: chebi.owl

EC 2.5.1.46 (deoxyhypusine synthase) inhibitor
type: Class
subclass of: EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor
has_related_synonym: (4-aminobutyl)lysine synthase inhibitor
has_related_synonym: (4-aminobutyl)lysine synthase inhibitors
definition: An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of deoxyhypusine synthase (EC 2.5.1.46).
id: CHEBI:133895
has_related_synonym: DHS inhibitor
has_related_synonym: DHS inhibitors
has_related_synonym: EC 2.5.1.46 (deoxyhypusine synthase) inhibitors
has_related_synonym: EC 2.5.1.46 inhibitor
has_related_synonym: EC 2.5.1.46 inhibitors
database_cross_reference: Wikipedia:Deoxyhypusine_synthase
has_related_synonym: [eIF-5A]-deoxyhypusine synthase inhibitor
has_related_synonym: [eIF-5A]-deoxyhypusine synthase inhibitors
has_related_synonym: [eIF5A-precursor]-lysine:spermidine 4-aminobutyltransferase (propane-1,3-diamine-forming) inhibitor
has_related_synonym: [eIF5A-precursor]-lysine:spermidine 4-aminobutyltransferase (propane-1,3-diamine-forming) inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: spermidine dehydrogenase inhibitor
has_related_synonym: spermidine dehydrogenase inhibitors
has_related_synonym: spermidine:eIF5A-lysine 4-aminobutyltransferase (propane-1,3-diamine-forming) inhibitor
has_related_synonym: spermidine:eIF5A-lysine 4-aminobutyltransferase (propane-1,3-diamine-forming) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

hypoxia-inducible factor pathway activator
type: Class
subclass of: activator
definition: An activator that activates the hypoxia inducible factor (HIF) pathway.
id: CHEBI:134083
has_related_synonym: HIF pathway activator
has_related_synonym: HIF pathway activators
database_cross_reference: Wikipedia:Hypoxia-inducible_factors
has_obo_namespace: chebi_ontology
has_related_synonym: hypoxia activator
has_related_synonym: hypoxia activators
has_related_synonym: hypoxia-inducible factor pathway activators
in_subset: 3 STAR
imported from: chebi.owl

EC 1.15.1.1 (superoxide dismutase) inhibitor
type: Class
subclass of: EC 1.15.* (oxidoreductase acting on superoxide as acceptor) inhibitor
id: CHEBI:134084
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

lipopolysaccharide biosynthesis inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
definition: Any compound that inhibits the biosynthesis of any lipopolysaccharide.
id: CHEBI:134108
has_obo_namespace: chebi_ontology
has_related_synonym: lipopolysaccharide biosynthesis inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.5.1.108 (UDP-3-O-acyl-N-acetylglucosamine deacetylase) inhibitor
type: Class
subclass of: EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor
definition: An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of UDP-3-O-acyl-N-acetylglucosamine deacetylase (EC 3.5.1.108).
id: CHEBI:134109
has_related_synonym: EC 3.5.1.108 (UDP-3-O-acyl-N-acetylglucosamine deacetylase) inhibitors
has_related_synonym: EC 3.5.1.108 inhibitor
has_related_synonym: EC 3.5.1.108 inhibitors
has_related_synonym: LpxC deacetylase inhibitor
has_related_synonym: LpxC deacetylase inhibitors
has_related_synonym: LpxC enzyme inhibitor
has_related_synonym: LpxC enzyme inhibitors
has_related_synonym: LpxC inhibitor
has_related_synonym: LpxC inhibitors
has_related_synonym: UDP-(3-O-(R-3-hydroxymyristoyl))-N-acetylglucosamine deacetylase inhibitor
has_related_synonym: UDP-(3-O-(R-3-hydroxymyristoyl))-N-acetylglucosamine deacetylase inhibitors
has_related_synonym: UDP-(3-O-acyl)-N-acetylglucosamine deacetylase inhibitor
has_related_synonym: UDP-(3-O-acyl)-N-acetylglucosamine deacetylase inhibitors
has_related_synonym: UDP-3-O-((R)-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase inhibitor
has_related_synonym: UDP-3-O-((R)-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase inhibitors
has_related_synonym: UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase inhibitor
has_related_synonym: UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase inhibitors
has_related_synonym: UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetyl-alpha-D-glucosamine amidohydrolase inhibitor
has_related_synonym: UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetyl-alpha-D-glucosamine amidohydrolase inhibitors
has_related_synonym: UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetylglucosamine amidohydrolase inhibitor
has_related_synonym: UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetylglucosamine amidohydrolase inhibitors
has_related_synonym: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase inhibitor
has_related_synonym: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase inhibitors
has_related_synonym: UDP-3-O-acyl-GlcNAc deacetylase inhibitor
has_related_synonym: UDP-3-O-acyl-GlcNAc deacetylase inhibitors
database_cross_reference: Wikipedia:UDP-3-O-N-acetylglucosamine_deacetylase
has_obo_namespace: chebi_ontology
has_related_synonym: deacetylase LpxC inhibitor
has_related_synonym: deacetylase LpxC inhibitors
in_subset: 3 STAR
imported from: chebi.owl

antidote to barbiturate poisoning
type: Class
subclass of: antidote
definition: A role borne by a molecule that acts to counteract or neutralise the deleterious effects of barbiturates.
id: CHEBI:134173
database_cross_reference: PMID:15432128
has_related_synonym: antidote to barbiturate overdose
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

platelet-activating factor receptor antagonist
type: Class
subclass of: antagonist
definition: An antagonist that acts at the platelet-activating factor receptor.
id: CHEBI:134182
has_related_synonym: PAF antagonist
has_related_synonym: PAF antagonists
has_obo_namespace: chebi_ontology
has_related_synonym: platelet-activating factor receptor antagonists
in_subset: 3 STAR
imported from: chebi.owl

EC 1.8.1.4 (dihydrolipoyl dehydrogenase) inhibitor
type: Class
subclass of: EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor
definition: An EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of dihydrolipoyl dehydrogenase (EC 1.8.1.4).
id: CHEBI:134545
has_related_synonym: E3 component of alpha-ketoacid dehydrogenase complexes inhibitor
has_related_synonym: E3 component of alpha-ketoacid dehydrogenase complexes inhibitors
has_related_synonym: EC 1.8.1.4 (dihydrolipoyl dehydrogenase) inhibitors
has_related_synonym: EC 1.8.1.4 inhibitor
has_related_synonym: EC 1.8.1.4 inhibitors
has_related_synonym: L-protein inhibitor
has_related_synonym: L-protein inhibitors
has_related_synonym: LDP-Glc inhibitor
has_related_synonym: LDP-Glc inhibitors
has_related_synonym: LDP-Val inhibitor
has_related_synonym: LDP-Val inhibitors
database_cross_reference: Wikipedia:Dihydrolipoamide_dehydrogenase
has_obo_namespace: chebi_ontology
has_related_synonym: dehydrolipoate dehydrogenase inhibitor
has_related_synonym: dehydrolipoate dehydrogenase inhibitors
has_related_synonym: diaphorase inhibitor
has_related_synonym: diaphorase inhibitors
has_related_synonym: dihydrolipoamide dehydrogenase inhibitor
has_related_synonym: dihydrolipoamide dehydrogenase inhibitors
has_related_synonym: dihydrolipoamide:NAD(+) oxidoreductase inhibitor
has_related_synonym: dihydrolipoamide:NAD(+) oxidoreductase inhibitors
has_related_synonym: dihydrolipoic dehydrogenase inhibitor
has_related_synonym: dihydrolipoic dehydrogenase inhibitors
has_related_synonym: dihydrothioctic dehydrogenase inhibitor
has_related_synonym: dihydrothioctic dehydrogenase inhibitors
has_related_synonym: glycine-cleavage system L-protein inhibitor
has_related_synonym: glycine-cleavage system L-protein inhibitors
has_related_synonym: lipoamide dehydrogenase (NADH) inhibitor
has_related_synonym: lipoamide dehydrogenase (NADH) inhibitors
has_related_synonym: lipoamide oxidoreductase (NADH) inhibitor
has_related_synonym: lipoamide oxidoreductase (NADH) inhibitors
has_related_synonym: lipoamide reductase (NADH) inhibitor
has_related_synonym: lipoamide reductase (NADH) inhibitors
has_related_synonym: lipoamide reductase inhibitor
has_related_synonym: lipoamide reductase inhibitors
has_related_synonym: lipoate dehydrogenase inhibitor
has_related_synonym: lipoate dehydrogenase inhibitors
has_related_synonym: lipoic acid dehydrogenase inhibitor
has_related_synonym: lipoic acid dehydrogenase inhibitors
has_related_synonym: lipoyl dehydrogenase inhibitor
has_related_synonym: lipoyl dehydrogenase inhibitors
has_related_synonym: protein-6-N-(dihydrolipoyl)lysine:NAD(+) oxidoreductase inhibitor
has_related_synonym: protein-6-N-(dihydrolipoyl)lysine:NAD(+) oxidoreductase inhibitors
has_related_synonym: protein-N(6)-(dihydrolipoyl)lysine:NAD(+) oxidoreductase inhibitor
has_related_synonym: protein-N(6)-(dihydrolipoyl)lysine:NAD(+) oxidoreductase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.4.2.8 (hypoxanthine phosphoribosyltransferase) inhibitor
type: Class
subclass of: EC 2.4.2.* (pentosyltransferase) inhibitor
has_related_synonym: 6-hydroxypurine phosphoribosyltransferase inhibitor
has_related_synonym: 6-mercaptopurine phosphoribosyltransferase inhibitor
definition: An EC 2.4.2.* (pentosyltransferase) inhibitor that interferes with the action of hypoxanthine phosphoribosyltransferase (EC 2.4.2.8).
id: CHEBI:136537
has_related_synonym: EC 2.4.2.8 (hypoxanthine phosphoribosyltransferase) inhibitors
has_related_synonym: EC 2.4.2.8 inhibitor
has_related_synonym: EC 2.4.2.8 inhibitors
has_related_synonym: GMP pyrophosphorylase inhibitor
has_related_synonym: GPRT inhibitor
has_related_synonym: HGPRTase inhibitor
has_related_synonym: HPRT inhibitor
has_related_synonym: IMP pyrophosphorylase inhibitor
has_related_synonym: IMP-GMP pyrophosphorylase inhibitor
has_related_synonym: IMP:diphosphate phospho-D-ribosyltransferase inhibitor
database_cross_reference: Wikipedia:Hypoxanthine-guanine_phosphoribosyltransferase
has_obo_namespace: chebi_ontology
has_related_synonym: guanine phosphoribosyltransferase inhibitor
has_related_synonym: guanine-hypoxanthine phosphoribosyltransferase inhibitor
has_related_synonym: guanosine 5'-phosphate pyrophosphorylase inhibitor
has_related_synonym: guanosine phosphoribosyltransferase inhibitor
has_related_synonym: guanylate pyrophosphorylase inhibitor
has_related_synonym: guanylic pyrophosphorylase inhibitor
has_related_synonym: hypoxanthine phosphoribosyltransferase (EC 2.4.2.8) inhibitor
has_related_synonym: hypoxanthine phosphoribosyltransferase (EC 2.4.2.8) inhibitors
has_related_synonym: hypoxanthine phosphoribosyltransferase inhibitor
has_related_synonym: hypoxanthine phosphoribosyltransferase inhibitors
has_related_synonym: hypoxanthine-guanine phosphoribosyltransferase inhibitor
has_related_synonym: inosinate pyrophosphorylase inhibitor
has_related_synonym: inosine 5'-phosphate pyrophosphorylas inhibitore
has_related_synonym: inosinic acid pyrophosphorylase inhibitor
has_related_synonym: inosinic pyrophosphorylase inhibitor
has_related_synonym: purine-6-thiol phosphoribosyltransferase inhibitor
has_related_synonym: transphosphoribosidase inhibitor
in_subset: 3 STAR
imported from: chebi.owl

EC 1.11.1.7 (peroxidase) inhibitor
type: Class
subclass of: EC 1.11.1.* (peroxidases) inhibitor
definition: An inhibitor of peroxidases (EC 1.11.1.*) that inhibits the action of peroxidase (EC 1.11.1.7).
has_related_synonym: Arthromyces ramosus peroxidase inhibitor
has_related_synonym: Arthromyces ramosus peroxidase inhibitors
id: CHEBI:136558
has_related_synonym: Coprinus cinereus peroxidase inhibitor
has_related_synonym: Coprinus cinereus peroxidase inhibitors
has_related_synonym: EC 1.11.1.7 (peroxidase) inhibitors
has_related_synonym: EC 1.11.1.7 inhibitor
has_related_synonym: EC 1.11.1.7 inhibitors
has_related_synonym: HRP inhibitor
has_related_synonym: HRP inhibitors
has_related_synonym: Japanese radish peroxidase inhibitor
has_related_synonym: Japanese radish peroxidase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: extensin peroxidase inhibitor
has_related_synonym: extensin peroxidase inhibitors
has_related_synonym: guaiacol peroxidase inhibitor
has_related_synonym: guaiacol peroxidase inhibitors
has_related_synonym: heme peroxidase inhibitor
has_related_synonym: heme peroxidase inhibitors
has_related_synonym: horseradish peroxidase (HRP) inhibitor
has_related_synonym: horseradish peroxidase (HRP) inhibitors
has_related_synonym: horseradish peroxidase inhibitor
has_related_synonym: horseradish peroxidase inhibitors
has_related_synonym: lactoperoxidase inhibitor
has_related_synonym: lactoperoxidase inhibitors
has_related_synonym: oxyperoxidase inhibitor
has_related_synonym: oxyperoxidase inhibitors
has_related_synonym: peroxidase (EC 1.11.1.7) inhibitor
has_related_synonym: peroxidase (EC 1.11.1.7) inhibitors
has_related_synonym: peroxidase inhibitor
has_related_synonym: peroxidase inhibitors
has_related_synonym: phenolic donor:hydrogen-peroxide oxidoreductase inhibitor
has_related_synonym: phenolic donor:hydrogen-peroxide oxidoreductase inhibitors
has_related_synonym: plant peroxidase inhibitor
has_related_synonym: plant peroxidase inhibitors
has_related_synonym: protoheme peroxidase inhibitor
has_related_synonym: protoheme peroxidase inhibitors
has_related_synonym: pyrocatechol peroxidase inhibitor
has_related_synonym: pyrocatechol peroxidase inhibitors
has_related_synonym: scopoletin peroxidase inhibitor
has_related_synonym: scopoletin peroxidase inhibitors
has_related_synonym: soybean peroxidase (SBP) inhibitor
has_related_synonym: soybean peroxidase (SBP) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

LRH-1 antagonist
type: Class
subclass of: antagonist
definition: An antagonist that acts at the liver receptor homologue-1.
id: CHEBI:136580
has_related_synonym: LRH-1 antagonists
has_related_synonym: NR5A2 antagonist
has_related_synonym: NR5A2 antagonists
database_cross_reference: Wikipedia:Liver_receptor_homolog-1
has_obo_namespace: chebi_ontology
has_related_synonym: liver receptor homolog-1 antagonist
has_related_synonym: liver receptor homolog-1 antagonists
has_related_synonym: liver receptor homologue-1 antagonist
has_related_synonym: liver receptor homologue-1 antagonists
has_related_synonym: nuclear receptor subfamily 5 group A member 2 antagonist
has_related_synonym: nuclear receptor subfamily 5 group A member 2 antagonists
in_subset: 3 STAR
imported from: chebi.owl

propesticide
type: Class
subclass of: pro-agent
subclass of: pesticide
definition: A prodrug that, on administration, undergoes chemical conversion by biochemical (enzymatic), chemical (possibly following an enzymatic step), or physical (e.g. photochemical) activation processes before becoming the pharmacologically active pesticide for which it is a propesticide.
database_cross_reference: AGR:IND84086009
id: CHEBI:136643
database_cross_reference: PMID:26449612
has_obo_namespace: chebi_ontology
has_related_synonym: pro-pesticide
has_related_synonym: pro-pesticides
has_related_synonym: propesticides
in_subset: 3 STAR
imported from: chebi.owl

proinsecticide
type: Class
subclass of: propesticide
subclass of: insecticide
definition: A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active insecticide for which it is a proinsecticide.
database_cross_reference: AGR:IND20386178
database_cross_reference: AGR:IND84086011
database_cross_reference: AGR:IND89021681
database_cross_reference: AGR:IND92003154
id: CHEBI:136644
database_cross_reference: PMID:16172027
database_cross_reference: PMID:26449612
database_cross_reference: PMID:27414472
database_cross_reference: PMID:27976502
has_obo_namespace: chebi_ontology
has_related_synonym: pro-insecticide
has_related_synonym: pro-insecticides
has_related_synonym: proinsecticides
in_subset: 3 STAR
imported from: chebi.owl

profungicide
type: Class
subclass of: propesticide
subclass of: fungicide
definition: A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active fungicide for which it is a profungicide.
id: CHEBI:136645
database_cross_reference: PMID:11929539
database_cross_reference: PMID:25746994
database_cross_reference: PMID:26449612
has_obo_namespace: chebi_ontology
has_related_synonym: pro-fungicide
has_related_synonym: pro-fungicides
has_related_synonym: profungicides
in_subset: 3 STAR
imported from: chebi.owl

proherbicide
type: Class
subclass of: propesticide
subclass of: herbicide
definition: A compound that, on administration, must undergo chemical conversion by biochemical (enzymatic), chemical (possibly following an enzymatic step), or physical (e.g. photochemical) activation processes before becoming the pharmacologically active herbicide for which it is a proherbicide.
database_cross_reference: AGR:IND43789627
id: CHEBI:136646
database_cross_reference: PMID:12232216
database_cross_reference: PMID:26449612
database_cross_reference: PMID:27280658
has_obo_namespace: chebi_ontology
has_related_synonym: pro-herbicide
has_related_synonym: pro-herbicides
has_related_synonym: proherbicides
in_subset: 3 STAR
imported from: chebi.owl

proacaricide
type: Class
subclass of: propesticide
subclass of: acaricide
definition: A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active insecticide for which it is a proacaricide.
id: CHEBI:136647
database_cross_reference: PMID:17046600
database_cross_reference: PMID:19330529
database_cross_reference: PMID:26449612
has_obo_namespace: chebi_ontology
has_related_synonym: pro-acaricide
has_related_synonym: pro-acaricides
has_related_synonym: proacaricides
in_subset: 3 STAR
imported from: chebi.owl

prosafener
type: Class
subclass of: herbicide safener
subclass of: propesticide
definition: A compound that, on administration, must undergo chemical conversion by biochemical (enzymatic), chemical (possibly following an enzymatic step), or physical (e.g. photochemical) activation processes before becoming the pharmacologically active herbicide savener for which it is a prosafener.
id: CHEBI:136648
database_cross_reference: PMID:26449612
has_obo_namespace: chebi_ontology
has_related_synonym: pro-safener
has_related_synonym: pro-safeners
has_related_synonym: prosafeners
in_subset: 3 STAR
imported from: chebi.owl

S100 calcium-binding protein B inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
definition: Any inhibitor of S100 calcium-binding protein B.
id: CHEBI:136651
has_related_synonym: S100 calcium-binding protein B inhibitors
has_related_synonym: S100B inhibitor
has_related_synonym: S100B inhibitors
database_cross_reference: Wikipedia:S100B
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

pro-agent
type: Class
subclass of: application
definition: A compound that, on administration, undergoes conversion by biochemical (enzymatic), chemical (possibly following an enzymatic step), or physical (e.g. photochemical) activation processes before becoming the active agent for which it is a pro-agent.
id: CHEBI:136859
database_cross_reference: PMID:26449612
has_obo_namespace: chebi_ontology
has_related_synonym: pro-agents
has_related_synonym: proagent
has_related_synonym: proagents
in_subset: 3 STAR
imported from: chebi.owl

antidote to sarin poisoning
type: Class
subclass of: antidote
definition: A role borne by a molecule that acts to counteract or neutralise the nerve agent sarin.
id: CHEBI:136860
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 4.4.1.14 (1-aminocyclopropane-1-carboxylate synthase) inhibitor
type: Class
subclass of: EC 4.4.1.* (C-S lyase) inhibitor
has_related_synonym: 1-aminocyclopropane-1-carboxylate synthase inhibitor
has_related_synonym: 1-aminocyclopropane-1-carboxylate synthase inhibitors
has_related_synonym: 1-aminocyclopropane-1-carboxylate synthetase inhibitor
has_related_synonym: 1-aminocyclopropane-1-carboxylate synthetase inhibitors
has_related_synonym: 1-aminocyclopropane-1-carboxylic acid synthase inhibitor
has_related_synonym: 1-aminocyclopropane-1-carboxylic acid synthase inhibitors
has_related_synonym: 1-aminocyclopropanecarboxylate synthase inhibitor
has_related_synonym: 1-aminocyclopropanecarboxylate synthase inhibitors
has_related_synonym: ACC synthase inhibitor
has_related_synonym: ACC synthase inhibitors
definition: An EC 4.4.1.* (C-S lyase) inhibitor that interferes with the action of 1-aminocyclopropane-1-carboxylate synthase (EC 4.4.1.14).
id: CHEBI:136984
has_related_synonym: EC 4.4.1.14 (1-aminocyclopropane-1-carboxylate synthase) inhibitors
has_related_synonym: EC 4.4.1.14 inhibitor
has_related_synonym: EC 4.4.1.14 inhibitors
has_related_synonym: S-adenosyl-L-methionine methylthioadenosine-lyase (1-aminocyclopropane-1-carboxylate-forming) inhibitor
has_related_synonym: S-adenosyl-L-methionine methylthioadenosine-lyase (1-aminocyclopropane-1-carboxylate-forming) inhibitors
has_related_synonym: S-adenosyl-L-methionine methylthioadenosine-lyase inhibitor
has_related_synonym: S-adenosyl-L-methionine methylthioadenosine-lyase inhibitors
has_related_synonym: aminocyclopropanecarboxylate synthase inhibitor
has_related_synonym: aminocyclopropanecarboxylate synthase inhibitors
has_related_synonym: aminocyclopropanecarboxylic acid synthase inhibitor
has_related_synonym: aminocyclopropanecarboxylic acid synthase inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

eukaryotic initiation factor 4F inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
definition: Any compound that inihibits the mammalian protein, eukaryotic initiation factor 4F.
id: CHEBI:137079
has_obo_namespace: chebi_ontology
has_related_synonym: eIF4F inhibitor
has_related_synonym: eIF4F inhibitors
has_related_synonym: eukaryotic initiation factor 4F inhibitors
in_subset: 3 STAR
imported from: chebi.owl

bromodomain-containing protein 4 inhibitor
type: Class
subclass of: BET bromodomain inhibitor
definition: Any inhibitor of bromodomain-containing protein 4 (BRD4).
has_related_synonym: BRD4 inhibitor
has_related_synonym: BRD4 inhibitors
id: CHEBI:137114
database_cross_reference: Wikipedia:BRD4
has_related_synonym: bromodomain-containing protein 4 inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.11.30 (receptor protein serine/threonine kinase) inhibitor
type: Class
subclass of: EC 2.7.11.* (protein-serine/threonine kinase) inhibitor
has_related_synonym: ATP:[receptor-protein] phosphotransferase inhibitor
has_related_synonym: ATP:[receptor-protein] phosphotransferase inhibitors
definition: An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the activity of receptor protein serine/threonine kinase (EC 2.7.11.30).
id: CHEBI:137123
has_related_synonym: EC 2.7.11.30 (receptor protein serine/threonine kinase) inhibitors
has_related_synonym: EC 2.7.11.30 inhibitor
has_related_synonym: EC 2.7.11.30 inhibitors
has_related_synonym: STK13 inhibitor
has_related_synonym: STK13 inhibitors
has_related_synonym: TGF-beta kinase inhibitor
has_related_synonym: TGF-beta kinase inhibitors
database_cross_reference: Wikipedia:Receptor_protein_serine/threonine_kinase
has_related_synonym: activin receptor kinase inhibitor
has_related_synonym: activin receptor kinase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of receptor protein serine/threonine kinase
has_related_synonym: receptor protein serine/threonine kinase (EC 2.7.11.30) inhibitor
has_related_synonym: receptor protein serine/threonine kinase (EC 2.7.11.30) inhibitors
has_related_synonym: receptor protein serine/threonine kinase inhibitor
has_related_synonym: receptor protein serine/threonine kinase inhibitors
has_related_synonym: receptor serine/threonine protein kinase inhibitor
has_related_synonym: receptor serine/threonine protein kinase inhibitors
has_related_synonym: receptor type I serine/threonine protein kinase inhibitor
has_related_synonym: receptor type I serine/threonine protein kinase inhibitors
has_related_synonym: receptor type II serine/threonine protein kinase inhibitor
has_related_synonym: receptor type II serine/threonine protein kinase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

capsaicin receptor agonist
type: Class
subclass of: agonist
definition: An agonist that binds to and activates capsaicin receptors
id: CHEBI:137401
has_related_synonym: TRPV1 agonist
has_related_synonym: TRPV1 agonists
database_cross_reference: Wikipedia:TRPV1
has_related_synonym: capsaicin agonist
has_related_synonym: capsaicin agonists
has_related_synonym: capsaicin receptor agonists
has_obo_namespace: chebi_ontology
has_related_synonym: transient receptor potential cation channel subfamily V member 1 agonist
has_related_synonym: transient receptor potential cation channel subfamily V member 1 agonists
has_related_synonym: vanilloid receptor 1 agonist
has_related_synonym: vanilloid receptor 1 agonists
in_subset: 3 STAR
imported from: chebi.owl

antihypotensive agent
type: Class
subclass of: cardiovascular drug
definition: A cardiovascular drug that tends to raise reduced blood pressure.
id: CHEBI:137431
database_cross_reference: Wikipedia:Antihypotensive_agent
has_related_synonym: antihypotensive agents
has_obo_namespace: chebi_ontology
has_related_synonym: pressor
has_related_synonym: pressors
has_related_synonym: vasopressor agent
has_related_synonym: vasopressor agents
in_subset: 3 STAR
imported from: chebi.owl

TRPA1 channel agonist
type: Class
subclass of: agonist
definition: An agonist at the transient receptor potential cation channel A1 (TRPA1).
id: CHEBI:137514
has_related_synonym: TRPA1 channel agonists
database_cross_reference: Wikipedia:TRPA1
has_obo_namespace: chebi_ontology
has_related_synonym: transient receptor potential ankyrin 1 agonist
has_related_synonym: transient receptor potential ankyrin 1 agonists
has_related_synonym: transient receptor potential cation channel A1 agonist
has_related_synonym: transient receptor potential cation channel A1 agonists
in_subset: 3 STAR
imported from: chebi.owl

EC 2.5.1.48 (cystathionine gamma-synthase) inhibitor
type: Class
subclass of: EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor
has_related_synonym: 4-O-succinyl-L-homoserine:L-cysteine S-(3-amino-3-carboxypropyl)transferase inhibitor
has_related_synonym: 4-O-succinyl-L-homoserine:L-cysteine S-(3-amino-3-carboxypropyl)transferase inhibitors
definition: An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of cystathionine gamma-synthase (EC 2.5.1.48).
id: CHEBI:137566
has_related_synonym: EC 2.5.1.48 (cystathionine gamma-synthase) inhibitors
has_related_synonym: EC 2.5.1.48 inhibitor
has_related_synonym: EC 2.5.1.48 inhibitors
has_related_synonym: O(4)-succinyl-L-homoserine:L-cysteine S-(3-amino-3-carboxypropyl)transferase inhibitor
has_related_synonym: O(4)-succinyl-L-homoserine:L-cysteine S-(3-amino-3-carboxypropyl)transferase inhibitors
has_related_synonym: O-succinyl-L-homoserine succinate-lyase (adding cysteine) inhibitor
has_related_synonym: O-succinyl-L-homoserine succinate-lyase (adding cysteine) inhibitors
has_related_synonym: O-succinylhomoserine (thiol)-lyase inhibitor
has_related_synonym: O-succinylhomoserine (thiol)-lyase inhibitors
has_related_synonym: O-succinylhomoserine synthase inhibitor
has_related_synonym: O-succinylhomoserine synthase inhibitors
has_related_synonym: O-succinylhomoserine synthetase inhibitor
has_related_synonym: O-succinylhomoserine synthetase inhibitors
database_cross_reference: Wikipedia:Cystathionine_gamma-synthase
has_obo_namespace: chebi_ontology
has_related_synonym: cystathionine gamma-synthase inhibitor
has_related_synonym: cystathionine gamma-synthase inhibitors
has_related_synonym: cystathionine synthase inhibitor
has_related_synonym: cystathionine synthase inhibitors
has_related_synonym: cystathionine synthetase inhibitor
has_related_synonym: cystathionine synthetase inhibitors
has_related_synonym: homoserine O-transsuccinylase inhibitor
has_related_synonym: homoserine O-transsuccinylase inhibitors
has_related_synonym: homoserine transsuccinylase inhibitor
has_related_synonym: homoserine transsuccinylase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.1.1.146 (11beta-hydroxysteroid dehydrogenase) inhibitor
type: Class
subclass of: EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor
has_related_synonym: 11beta-hydroxy steroid dehydrogenase inhibitor
has_related_synonym: 11beta-hydroxy steroid dehydrogenase inhibitors
has_related_synonym: 11beta-hydroxysteroid dehydrogenase inhibitor
has_related_synonym: 11beta-hydroxysteroid dehydrogenase inhibitors
has_related_synonym: 11beta-hydroxysteroid dehydrogenase type 1 inhibitor
has_related_synonym: 11beta-hydroxysteroid dehydrogenase type 1 inhibitors
has_related_synonym: 11beta-hydroxysteroid:NADP(+) 11-oxidoreductase inhibitor
has_related_synonym: 11beta-hydroxysteroid:NADP(+) 11-oxidoreductase inhibitors
definition: An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of 11beta-hydroxysteroid dehydrogenase (EC 1.1.1.146).
id: CHEBI:137626
has_related_synonym: EC 1.1.1.146 (11beta-hydroxysteroid dehydrogenase) inhibitors
has_related_synonym: EC 1.1.1.146 inhibitor
has_related_synonym: EC 1.1.1.146 inhibitors
has_related_synonym: beta-hydroxysteroid dehydrogenase inhibitor
has_related_synonym: beta-hydroxysteroid dehydrogenase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: corticosteroid 11-reductase inhibitor
has_related_synonym: corticosteroid 11-reductase inhibitors
has_related_synonym: corticosteroid 11beta-dehydrogenase inhibitor
has_related_synonym: corticosteroid 11beta-dehydrogenase inhibitors
has_related_synonym: dehydrogenase, 11beta-hydroxy steroid inhibitor
has_related_synonym: dehydrogenase, 11beta-hydroxy steroid inhibitors
in_subset: 3 STAR
imported from: chebi.owl

Papio hamadryas metabolite
type: Class
subclass of: mammalian metabolite
definition: Any mammalian metabolite produced during a metabolic reaction in Papio hamadryas.
id: CHEBI:137684
has_related_synonym: P. hamadryas metabolite
has_related_synonym: P. hamadryas metabolites
has_related_synonym: Papio hamadryas metabolites
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

anxiogenic
type: Class
subclass of: psychotropic drug
definition: Any psychotropic drug that induces anxiety or panic.
id: CHEBI:137736
database_cross_reference: Wikipedia:Anxiogenic
has_related_synonym: anxiogenics
has_obo_namespace: chebi_ontology
has_related_synonym: panicogenic
has_related_synonym: panicogenics
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.22.56 (caspase-3) inhibitor
type: Class
subclass of: EC 3.4.22.* (cysteine endopeptidase) inhibitor
definition: An EC 3.4.22.* (cysteine endopeptidase) inhibitor that interferes with the action of caspase-3 (EC 3.4.22.56).
has_related_synonym: CASP-3 inhibitor
has_related_synonym: CASP-3 inhibitors
id: CHEBI:138014
has_related_synonym: CPP32 inhibitor
has_related_synonym: CPP32 inhibitors
has_related_synonym: EC 3.4.22.56 (caspase-3) inhibitors
has_related_synonym: EC 3.4.22.56 inhibitor
has_related_synonym: EC 3.4.22.56 inhibitors
database_cross_reference: Wikipedia:Caspase_3
has_related_synonym: apopain inhibitor
has_related_synonym: apopain inhibitors
has_related_synonym: caspase-3 (EC 3.4.22.56) inhibitor
has_related_synonym: caspase-3 (EC 3.4.22.56) inhibitors
has_related_synonym: caspase-3 inhibitor
has_related_synonym: caspase-3 inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: yama protein inhibitor
has_related_synonym: yama protein inhibitors
in_subset: 3 STAR
imported from: chebi.owl

endocrine disruptor
type: Class
subclass of: hormone receptor modulator
definition: Any compound that can disrupt the functions of the endocrine (hormone) system
id: CHEBI:138015
database_cross_reference: PMID:27929035
database_cross_reference: PMID:28356401
database_cross_reference: PMID:28526231
database_cross_reference: Wikipedia:Endocrine_disruptor
has_obo_namespace: chebi_ontology
has_related_synonym: endocrine disrupting chemical
has_related_synonym: endocrine disrupting chemicals
has_related_synonym: endocrine disrupting compound
has_related_synonym: endocrine disrupting compounds
has_related_synonym: endocrine disruptors
has_related_synonym: endocrine-disrupting chemical
has_related_synonym: endocrine-disrupting chemicals
has_related_synonym: hormonally active agent
has_related_synonym: hormonally active agents
in_subset: 3 STAR
imported from: chebi.owl

ATPase motor cytoplasmic dynein inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
has_related_synonym: ATPase motor cytoplasmic dynein inhibitors
definition: Any inhibitor of ATPase motor cytoplasmic dynein.
id: CHEBI:138090
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

inorganic acid
type: Class
subclass of: Bronsted acid
definition: A Bronsted acid derived from one or more inorganic compounds. Inorganic acids (also known as mineral acids) form hydrons and conjugate base ions when dissolved in water.
id: CHEBI:138103
database_cross_reference: Wikipedia:Mineral_acid
has_obo_namespace: chebi_ontology
has_related_synonym: inorganic acids
has_related_synonym: mineral acid
has_related_synonym: mineral acids
in_subset: 3 STAR
imported from: chebi.owl

neuropeptide Y2 receptor agonist
type: Class
subclass of: agonist
id: CHEBI:138168
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

carotenoid biosynthesis inhibitor
type: Class
subclass of: pathway inhibitor
definition: Any pathway inhibitor that acts on the carotenoid biosynthesis pathway.
id: CHEBI:138208
has_related_synonym: carotenogenesis inhibitor
has_related_synonym: carotenogenesis inhibitors
has_related_synonym: carotenoid biosynthesis inhibitors
has_related_synonym: carotenoid-biosynthesis inhibitor
has_related_synonym: carotenoid-biosynthesis inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

RhoA inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
definition: Any inhibitor that interferes with the action of the protein RhoA.
id: CHEBI:138380
has_related_synonym: Ras homolog gene family, member A inhibitor
has_related_synonym: Ras homolog gene family, member A inhibitors
has_related_synonym: RhoA GTPase inhibitor
has_related_synonym: RhoA GTPase inhibitors
has_related_synonym: RhoA inhibitors
database_cross_reference: Wikipedia:RHOA
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

RhoC inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
definition: Any inhibitor that interferes with the action of the protein RhoC.
id: CHEBI:138381
has_related_synonym: Ras homolog gene family, member C inhibitor
has_related_synonym: Ras homolog gene family, member C inhibitors
has_related_synonym: RhoC GTPase inhibitor
has_related_synonym: RhoC GTPase inhibitors
has_related_synonym: RhoC inhibitors
database_cross_reference: Wikipedia:RhoC
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 1.1.1.159 (7alpha-hydroxysteroid dehydrogenase) inhibitor
type: Class
subclass of: EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor
has_related_synonym: 7alpha-HSDH inhibitor
has_related_synonym: 7alpha-HSDH inhibitors
has_related_synonym: 7alpha-hydroxy steroid dehydrogenase inhibitor
has_related_synonym: 7alpha-hydroxy steroid dehydrogenase inhibitors
has_related_synonym: 7alpha-hydroxysteroid dehydrogenase inhibitor
has_related_synonym: 7alpha-hydroxysteroid dehydrogenase inhibitors
has_related_synonym: 7alpha-hydroxysteroid:NAD+ 7-oxidoreductase inhibitor
has_related_synonym: 7alpha-hydroxysteroid:NAD+ 7-oxidoreductase inhibitors
definition: An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD+ or NADP+ acceptor) inhibitor that interferes with the action of 7alpha-hydroxysteroid dehydrogenase (EC 1.1.1.159).
id: CHEBI:138390
has_related_synonym: EC 1.1.1.159 (7alpha-hydroxysteroid dehydrogenase) inhibitors
has_related_synonym: EC 1.1.1.159 inhibitor
has_related_synonym: EC 1.1.1.159 inhibitors
database_cross_reference: Wikipedia:7alpha-hydroxysteroid_dehydrogenase
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

angiotensin receptor agonist
type: Class
subclass of: hormone agonist
definition: A hormone antagonist that acts at angiotensin receptors.
id: CHEBI:138416
has_related_synonym: angiotensin receptor agonists
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

autophagy inducer
type: Class
subclass of: biochemical role
definition: Any compound that induces the process of autophagy (the self-digestion of one or more components of a cell through the action of enzymes originating within the same cell).
id: CHEBI:138880
has_related_synonym: autophagocytosis inducer
has_related_synonym: autophagocytosis inducers
has_related_synonym: autophagy inducers
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

prostaglandin receptor antagonist
type: Class
subclass of: antagonist
definition: An antagonist that binds to and blocks the activity of prostaglandin receptors.
id: CHEBI:138887
database_cross_reference: Wikipedia:Prostaglandin_receptor
has_obo_namespace: chebi_ontology
has_related_synonym: prostaglandin receptor antagonists
has_related_synonym: prostanoid receptor antagonist
has_related_synonym: prostanoid receptor antagonists
in_subset: 3 STAR
imported from: chebi.owl

EC 6.3.5.* (carbon-nitrogen ligases with glutamine as amido-N-donor) inhibitor
type: Class
subclass of: EC 6.3.* (C-N bond-forming ligase) inhibitor
definition: An EC 6.3.* (C-N bond-forming ligase) inhibitor that interferes with the action of any carbon-nitrogen ligases with glutamine as amido-N-donor (EC 6.3.5.*).
id: CHEBI:138920
has_related_synonym: EC 6.3.5.* (carbon-nitrogen ligases with glutamine as amido-N-donor) inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 6.3.5.5 [carbamoyl-phosphate synthase (glutamine-hydrolysing)] inhibitor
type: Class
subclass of: EC 6.3.5.* (carbon-nitrogen ligases with glutamine as amido-N-donor) inhibitor
definition: An EC 6.3.5.* (carbon-nitrogen ligases with glutamine as amido-N-donor) inhibitor that interferes with the action of carbamoyl-phosphate synthase (glutamine-hydrolysing) (EC 6.3.5.5).
has_related_synonym: CAD inhibitor
has_related_synonym: CAD inhibitors
id: CHEBI:138921
has_related_synonym: CPS inhibitor
has_related_synonym: CPS inhibitors
has_related_synonym: EC 6.3.5.5 [carbamoyl-phosphate synthase (glutamine-hydrolysing)] inhibitors
has_related_synonym: EC 6.3.5.5 inhibitor
has_related_synonym: EC 6.3.5.5 inhibitors
has_related_synonym: GD-CPSase inhibitor
has_related_synonym: GD-CPSase inhibitors
has_related_synonym: HCO3(-):L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) inhibitor
has_related_synonym: HCO3(-):L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) inhibitors
has_related_synonym: carA inhibitor
has_related_synonym: carA inhibitors
has_related_synonym: carB inhibitor
has_related_synonym: carB inhibitors
has_related_synonym: carbamoyl phosphate synthetase inhibitor
has_related_synonym: carbamoyl phosphate synthetase inhibitors
has_related_synonym: carbamoyl-phosphate synthase (glutamine-hydrolysing) (EC 6.3.5.5) inhibitor
has_related_synonym: carbamoyl-phosphate synthase (glutamine-hydrolysing) (EC 6.3.5.5) inhibitors
has_related_synonym: carbamoyl-phosphate synthetase (glutamine-hydrolysing) inhibitor
has_related_synonym: carbamoyl-phosphate synthetase (glutamine-hydrolysing) inhibitors
has_related_synonym: carbamoylphosphate synthetase II inhibitor
has_related_synonym: carbamoylphosphate synthetase II inhibitors
has_related_synonym: carbamyl phosphate synthetase (glutamine) inhibitor
has_related_synonym: carbamyl phosphate synthetase (glutamine) inhibitors
has_related_synonym: carbon-dioxide:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) inhibitor
has_related_synonym: carbon-dioxide:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: glutamine-dependent carbamoyl-phosphate synthase inhibitor
has_related_synonym: glutamine-dependent carbamoyl-phosphate synthase inhibitors
has_related_synonym: glutamine-dependent carbamyl phosphate synthetase inhibitor
has_related_synonym: glutamine-dependent carbamyl phosphate synthetase inhibitors
has_related_synonym: hydrogen-carbonate:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) inhibitor
has_related_synonym: hydrogen-carbonate:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 6.3.4.* (other carbon--nitrogen ligases) inhibitor
type: Class
subclass of: EC 6.3.* (C-N bond-forming ligase) inhibitor
definition: Any EC 6.3.* (C-N bond-forming ligase) inhibitor that interferes with the action of 'other carbon--nitrogen ligases.
id: CHEBI:138924
has_related_synonym: EC 6.3.4.* (other carbon--nitrogen ligases) inhibitors
has_related_synonym: EC 6.3.4.* inhibitor
has_related_synonym: EC 6.3.4.* inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 6.3.4.2 [CTP synthase (glutamine hydrolyzing)] inhibitor
type: Class
subclass of: EC 6.3.4.* (other carbon--nitrogen ligases) inhibitor
definition: Any EC 6.3.4.* (other carbon--nitrogen ligases) inhibitor that interferes with the action of CTP synthase (glutamine hydrolyzing) (EC 6.3.4.2).
id: CHEBI:138925
has_related_synonym: CTP synthase (glutamine hydrolyzing) (EC6.3.4.2) inhibitor
has_related_synonym: CTP synthase (glutamine hydrolyzing) (EC6.3.4.2) inhibitors
has_related_synonym: CTP synthase (glutamine hydrolyzing) inhibitor
has_related_synonym: CTP synthase (glutamine hydrolyzing) inhibitors
has_related_synonym: CTP synthetase inhibitor
has_related_synonym: CTP synthetase inhibitors
has_related_synonym: CTPS inhibitor
has_related_synonym: CTPS inhibitors
has_related_synonym: EC 6.3.4.2 [CTP synthase (glutamine hydrolyzing)] inhibitors
has_related_synonym: EC 6.3.4.2 inhibitor
has_related_synonym: EC 6.3.4.2 inhibitors
has_related_synonym: UTP--ammonia ligase inhibitor
has_related_synonym: UTP-ammonia ligase inhibitors
has_related_synonym: UTP:L-glutamine amido-ligase (ADP-forming) inhibitor
has_related_synonym: UTP:L-glutamine amido-ligase (ADP-forming) inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: cytidine triphosphate synthetase inhibitor
has_related_synonym: cytidine triphosphate synthetase inhibitors
has_related_synonym: pyrG inhibitor
has_related_synonym: pyrG inhibitors
has_related_synonym: uridine triphosphate aminase inhibitor
has_related_synonym: uridine triphosphate aminase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 6.3.5.3 (phosphoribosylformylglycinamidine synthase) inhibitor
type: Class
subclass of: EC 6.3.5.* (carbon-nitrogen ligases with glutamine as amido-N-donor) inhibitor
has_related_synonym: 2-N-formyl-1-N-(5-phospho-D-ribosyl)glycinamide:L-glutamine amido-ligase (ADP-forming) inhibitor
has_related_synonym: 2-N-formyl-1-N-(5-phospho-D-ribosyl)glycinamide:L-glutamine amido-ligase (ADP-forming) inhibitors
has_related_synonym: 5'-phosphoribosylformylglycinamide:L-glutamine amido-ligase (ADP-forming) inhibitor
has_related_synonym: 5'-phosphoribosylformylglycinamide:L-glutamine amido-ligase (ADP-forming) inhibitors
definition: Any EC 6.3.5.* (carbon-nitrogen ligases with glutamine as amido-N-donor) inhibitor that interferes with the action of phosphoribosylformylglycinamidine synthase (EC 6.3.5.3).
id: CHEBI:138927
has_related_synonym: EC 6.3.5.3 (phosphoribosylformylglycinamidine synthase) inhibitors
has_related_synonym: EC 6.3.5.3 inhibitor
has_related_synonym: EC 6.3.5.3 inhibitors
has_related_synonym: FGAM synthase inhibitor
has_related_synonym: FGAM synthase inhibitors
has_related_synonym: FGAM synthetase inhibitor
has_related_synonym: FGAM synthetase inhibitors
has_related_synonym: FGAR amidotransferase inhibitor
has_related_synonym: FGAR amidotransferase inhibitors
has_related_synonym: FGARAT inhibitor
has_related_synonym: FGARAT inhibitors
has_related_synonym: N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide:L-glutamine amido-ligase (ADP-forming) inhibitor
has_related_synonym: N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide:L-glutamine amido-ligase (ADP-forming) inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: formylglycinamide ribonucloetide amidotransferase inhibitor
has_related_synonym: formylglycinamide ribonucloetide amidotransferase inhibitors
has_related_synonym: formylglycinamide ribotide amidotransferase inhibitor
has_related_synonym: formylglycinamide ribotide amidotransferase inhibitors
has_related_synonym: phosphoribosylformylglycinamidine synthase inhibitor
has_related_synonym: phosphoribosylformylglycinamidine synthase inhibitors
has_related_synonym: phosphoribosylformylglycinamidine synthetase inhibitor
has_related_synonym: phosphoribosylformylglycinamidine synthetase inhibitors
has_related_synonym: phosphoribosylformylglycineamidine synthetase inhibitor
has_related_synonym: phosphoribosylformylglycineamidine synthetase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 6.3.5.2 [GMP synthase (glutamine-hydrolysing)] inhibitor
type: Class
subclass of: EC 6.3.5.* (carbon-nitrogen ligases with glutamine as amido-N-donor) inhibitor
definition: An EC 6.3.5.* (carbon-nitrogen ligases with glutamine as amido-N-donor) inhibitor that interferes with the action of GMP synthase (glutamine-hydrolysing) (EC 6.3.5.2).
id: CHEBI:138928
has_related_synonym: EC 6.3.5.2 [GMP synthase (glutamine-hydrolysing)] inhibitors
has_related_synonym: EC 6.3.5.2 inhibitor
has_related_synonym: EC 6.3.5.2 inhibitors
has_related_synonym: GMP synthase (glutamine-hydrolysing) inhibitor
has_related_synonym: GMP synthase (glutamine-hydrolysing) inhibitors
has_related_synonym: GMP synthetase (glutamine-hydrolysing) inhibitor
has_related_synonym: GMP synthetase (glutamine-hydrolysing) inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: guanosine 5'-monophosphate synthetase inhibitor
has_related_synonym: guanosine 5'-monophosphate synthetase inhibitors
has_related_synonym: guanosine monophosphate synthetase (glutamine-hydrolyzing) inhibitor
has_related_synonym: guanosine monophosphate synthetase (glutamine-hydrolyzing) inhibitors
has_related_synonym: guanylate synthetase (glutamine-hydrolyzing) inhibitor
has_related_synonym: guanylate synthetase (glutamine-hydrolyzing) inhibitors
has_related_synonym: xanthosine 5'-phosphate amidotransferase inhibitor
has_related_synonym: xanthosine 5'-phosphate amidotransferase inhibitors
has_related_synonym: xanthosine-5'-phosphate:L-glutamine amido-ligase (AMP-forming) inhibitor
has_related_synonym: xanthosine-5'-phosphate:L-glutamine amido-ligase (AMP-forming) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

glutamine antagonist
type: Class
subclass of: antagonist
definition: An antagonist that acts on glutamine receptors.
id: CHEBI:138931
database_cross_reference: PMID:4400179
has_obo_namespace: chebi_ontology
has_related_synonym: glutamine antagonists
in_subset: 3 STAR
imported from: chebi.owl

EC 4.1.1.39 (ribulose-bisphosphate carboxylase) inhibitor
type: Class
subclass of: EC 4.1.1.* (carboxy-lyase) inhibitor
has_related_synonym: 3-phospho-D-glycerate carboxy-lyase (dimerizing) inhibitor
has_related_synonym: 3-phospho-D-glycerate carboxy-lyase (dimerizing) inhibitors
has_related_synonym: 3-phospho-D-glycerate carboxy-lyase (dimerizing; D-ribulose-1,5-bisphosphate-forming) inhibitor
has_related_synonym: 3-phospho-D-glycerate carboxy-lyase (dimerizing; D-ribulose-1,5-bisphosphate-forming) inhibitors
definition: An EC 4.1.1.* (carboxy-lyase) inhibitor that interferes with the action of ribulose-bisphosphate carboxylase (EC 4.1.1.39).
id: CHEBI:138938
has_related_synonym: D-ribulose 1,5-bisphosphate carboxylase inhibitor
has_related_synonym: D-ribulose 1,5-bisphosphate carboxylase inhibitors
has_related_synonym: D-ribulose 1,5-diphosphate carboxylase inhibitor
has_related_synonym: D-ribulose 1,5-diphosphate carboxylase inhibitors
has_related_synonym: EC 4.1.1.39 (ribulose-bisphosphate carboxylase) inhibitors
has_related_synonym: EC 4.1.1.39 inhibitor
has_related_synonym: EC 4.1.1.39 inhibitors
has_related_synonym: RuBP carboxylase inhibitor
has_related_synonym: RuBP carboxylase inhibitors
has_related_synonym: RuBisCO inhibitor
has_related_synonym: RuBisCO inhibitors
database_cross_reference: Wikipedia:RuBisCO
has_related_synonym: carboxydismutase inhibitor
has_related_synonym: carboxydismutase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: diphosphoribulose carboxylase inhibitor
has_related_synonym: diphosphoribulose carboxylase inhibitors
has_related_synonym: ribulose 1,5-bisphosphate carboxylase inhibitor
has_related_synonym: ribulose 1,5-bisphosphate carboxylase inhibitors
has_related_synonym: ribulose 1,5-bisphosphate carboxylase/oxygenase inhibitor
has_related_synonym: ribulose 1,5-bisphosphate carboxylase/oxygenase inhibitors
has_related_synonym: ribulose 1,5-diphosphate carboxylase inhibitor
has_related_synonym: ribulose 1,5-diphosphate carboxylase inhibitors
has_related_synonym: ribulose 1,5-diphosphate carboxylase/oxygenase inhibitor
has_related_synonym: ribulose 1,5-diphosphate carboxylase/oxygenase inhibitors
has_related_synonym: ribulose bisphosphate carboxylase/oxygenase inhibitor
has_related_synonym: ribulose bisphosphate carboxylase/oxygenase inhibitors
has_related_synonym: ribulose diphosphate carboxylase inhibitor
has_related_synonym: ribulose diphosphate carboxylase inhibitors
has_related_synonym: ribulose diphosphate carboxylase/oxygenase inhibitor
has_related_synonym: ribulose diphosphate carboxylase/oxygenase inhibitors
has_related_synonym: ribulose-bisphosphate carboxylase inhibitor
has_related_synonym: ribulose-bisphosphate carboxylase inhibitors
has_related_synonym: rubisco inhibitor
has_related_synonym: rubisco inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.4.2.14 (amidophosphoribosyltransferase) inhibitor
type: Class
subclass of: EC 2.4.2.* (pentosyltransferase) inhibitor
has_related_synonym: 5'-phosphoribosylpyrophosphate amidotransferase inhibitor
has_related_synonym: 5'-phosphoribosylpyrophosphate amidotransferase inhibitors
has_related_synonym: 5-phospho-beta-D-ribosylamine:diphosphate phospho-alpha-D-ribosyltransferase (glutamate-amidating) inhibitor
has_related_synonym: 5-phospho-beta-D-ribosylamine:diphosphate phospho-alpha-D-ribosyltransferase (glutamate-amidating) inhibitors
has_related_synonym: 5-phosphoribosyl-1-pyrophosphate amidotransferase inhibitor
has_related_synonym: 5-phosphoribosyl-1-pyrophosphate amidotransferase inhibitors
has_related_synonym: 5-phosphoribosylamine:diphosphate phospho-alpha-D-ribosyltransferase (glutamate-amidating) inhibitor
has_related_synonym: 5-phosphoribosylamine:diphosphate phospho-alpha-D-ribosyltransferase (glutamate-amidating) inhibitors
has_related_synonym: 5-phosphororibosyl-1-pyrophosphate amidotransferase inhibitor
has_related_synonym: 5-phosphororibosyl-1-pyrophosphate amidotransferase inhibitors
definition: Any EC 2.4.2.* (pentosyltransferase) inhibitor that interferes with the action of amidophosphoribosyltransferase (EC 2.4.2.14).
id: CHEBI:138952
has_related_synonym: EC 2.4.2.14 (amidophosphoribosyltransferase) inhibitors
has_related_synonym: EC 2.4.2.14 inhibitor
has_related_synonym: EC 2.4.2.14 inhibitors
database_cross_reference: Wikipedia:Amidophosphoribosyltransferase
has_related_synonym: alpha-5-phosphoribosyl-1-pyrophosphate amidotransferase inhibitor
has_related_synonym: alpha-5-phosphoribosyl-1-pyrophosphate amidotransferase inhibitors
has_related_synonym: amidophosphoribosyltransferase (EC 2.4.2.14) inhibitor
has_related_synonym: amidophosphoribosyltransferase (EC 2.4.2.14) inhibitors
has_related_synonym: amidophosphoribosyltransferase inhibitor
has_related_synonym: amidophosphoribosyltransferase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: glutamine 5-phosphoribosylpyrophosphate amidotransferase inhibitor
has_related_synonym: glutamine 5-phosphoribosylpyrophosphate amidotransferase inhibitors
has_related_synonym: glutamine phosphoribosyldiphosphate amidotransferase inhibitor
has_related_synonym: glutamine phosphoribosyldiphosphate amidotransferase inhibitors
has_related_synonym: glutamine phosphoribosylpyrophosphate amidotransferase inhibitor
has_related_synonym: glutamine phosphoribosylpyrophosphate amidotransferase inhibitors
has_related_synonym: glutamine ribosylpyrophosphate 5-phosphate amidotransferase inhibitor
has_related_synonym: glutamine ribosylpyrophosphate 5-phosphate amidotransferase inhibitors
has_related_synonym: phosphoribose pyrophosphate amidotransferase inhibitor
has_related_synonym: phosphoribose pyrophosphate amidotransferase inhibitors
has_related_synonym: phosphoribosyl pyrophosphate amidotransferase inhibitor
has_related_synonym: phosphoribosyl pyrophosphate amidotransferase inhibitors
has_related_synonym: phosphoribosyldiphosphate 5-amidotransferase inhibitor
has_related_synonym: phosphoribosyldiphosphate 5-amidotransferase inhibitors
has_related_synonym: phosphoribosylpyrophosphate glutamyl amidotransferase inhibitor
has_related_synonym: phosphoribosylpyrophosphate glutamyl amidotransferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 6.3.5.1 [NAD(+) synthase (glutamine-hydrolysing)] inhibitor
type: Class
subclass of: EC 6.3.5.* (carbon-nitrogen ligases with glutamine as amido-N-donor) inhibitor
definition: Any EC 6.3.5.* (carbon-nitrogen ligases with glutamine as amido-N-donor) inhibitor that interferes with the action of NAD(+) synthase (glutamine-hydrolysing) (EC 6.3.5.1).
id: CHEBI:138953
has_related_synonym: DPN synthetase inhibitor
has_related_synonym: DPN synthetase inhibitors
has_related_synonym: EC 6.3.5.1 [NAD(+) synthase (glutamine-hydrolysing)] inhibitors
has_related_synonym: EC 6.3.5.1 inhibitor
has_related_synonym: EC 6.3.5.1 inhibitors
has_related_synonym: NAD synthetase (glutamine-hydrolysing) inhibitor
has_related_synonym: NAD synthetase (glutamine-hydrolysing) inhibitors
has_related_synonym: NAD(+) synthase (glutamine-hydrolysing) (EC 6.3.5.1) inhibitor
has_related_synonym: NAD(+) synthase (glutamine-hydrolysing) (EC 6.3.5.1) inhibitors
has_related_synonym: NAD(+) synthase (glutamine-hydrolysing) inhibitor
has_related_synonym: NAD(+) synthase (glutamine-hydrolysing) inhibitors
has_related_synonym: NAD(+) synthetase (glutamine-hydrolyzing) inhibitor
has_related_synonym: NAD(+) synthetase (glutamine-hydrolyzing) inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: deamido-NAD(+):L-glutamine amido-ligase (AMP-forming) inhibitor
has_related_synonym: deamido-NAD(+):L-glutamine amido-ligase (AMP-forming) inhibitors
has_related_synonym: desamidonicotinamide adenine dinucleotide amidotransferase inhibitor
has_related_synonym: desamidonicotinamide adenine dinucleotide amidotransferase inhibitors
has_related_synonym: nicotinamide adenine dinucleotide synthetase (glutamine) inhibitor
has_related_synonym: nicotinamide adenine dinucleotide synthetase (glutamine) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 6.3.5.4 [asparagine synthase (glutamine-hydrolysing)] inhibitor
type: Class
subclass of: EC 6.3.5.* (carbon-nitrogen ligases with glutamine as amido-N-donor) inhibitor
has_related_synonym: AS inhibitor
has_related_synonym: AS inhibitors
has_related_synonym: AS-B inhibitor
has_related_synonym: AS-B inhibitors
definition: Any EC 6.3.5.* (carbon-nitrogen ligases with glutamine as amido-N-donor) inhibitor that interferes with the action of asparagine synthase (glutamine-hydrolysing), EC 6.3.5.4.
id: CHEBI:138956
has_related_synonym: EC 6.3.5.4 [asparagine synthase (glutamine-hydrolysing)] inhibitors
has_related_synonym: EC 6.3.5.4 inhibitor
has_related_synonym: EC 6.3.5.4 inhibitors
has_related_synonym: L-aspartate:L-glutamine amido-ligase (AMP-forming) inhibitor
has_related_synonym: L-aspartate:L-glutamine amido-ligase (AMP-forming) inhibitors
has_related_synonym: asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) inhibitor
has_related_synonym: asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) inhibitors
has_related_synonym: asparagine synthase (glutamine-hydrolysing) inhibitor
has_related_synonym: asparagine synthase (glutamine-hydrolysing) inhibitors
has_related_synonym: asparagine synthetase (glutamine-hydrolysing) inhibitor
has_related_synonym: asparagine synthetase (glutamine-hydrolysing) inhibitors
has_related_synonym: asparagine synthetase B inhibitor
has_related_synonym: asparagine synthetase B inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: glutamine-dependent asparagine synthetase inhibitor
has_related_synonym: glutamine-dependent asparagine synthetase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

quorum sensing inhibitor
type: Class
subclass of: inhibitor
definition: Any compound that interferes with bacterial communication (quorum sensing, QS).
id: CHEBI:138977
database_cross_reference: PMID:16549654
database_cross_reference: PMID:22286987
database_cross_reference: PMID:24126008
database_cross_reference: PMID:25189863
database_cross_reference: PMID:25430794
database_cross_reference: PMID:27977197
database_cross_reference: PMID:28094526
database_cross_reference: PMID:28241461
database_cross_reference: PMID:28350449
database_cross_reference: PMID:28421612
database_cross_reference: PMID:28554093
database_cross_reference: PMID:28789564
database_cross_reference: PMID:28826080
database_cross_reference: PMID:28851971
database_cross_reference: PMID:29026943
database_cross_reference: PMID:29085409
has_related_synonym: QS inhibitor
has_related_synonym: QS inhibitors
has_related_synonym: QSI
has_related_synonym: QSIs
has_obo_namespace: chebi_ontology
has_related_synonym: quorum sensing inhibitors
in_subset: 3 STAR
imported from: chebi.owl

thromboxane A2 agonist
type: Class
subclass of: agonist
definition: An agonist that binds to and activates thromboxane A2 receptors.
id: CHEBI:139044
has_related_synonym: TXA2/PGH2 agonist
has_related_synonym: TXA2/PGH2 agonists
has_related_synonym: TXA2/PGH2 receptor agonist
has_related_synonym: TXA2/PGH2 receptor agonists
has_obo_namespace: chebi_ontology
has_related_synonym: thromboxane A2 agonists
has_related_synonym: thromboxane A2 receptor agonist
has_related_synonym: thromboxane A2 receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

PERK inhibitor
type: Class
subclass of: EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor
definition: An EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor that inhibits the expression of protein kinase RNA-like endoplasmic reticulum kinase.
id: CHEBI:139055
has_related_synonym: PERK inhibitors
has_related_synonym: PKR-like endoplasmic reticulum kinase inhibitor
has_related_synonym: PKR-like endoplasmic reticulum kinase inhibitors
database_cross_reference: PMID:24107775
database_cross_reference: Wikipedia:PERK_inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: protein kinase R-like endoplasmic reticulum kinase inhibitor
has_related_synonym: protein kinase R-like endoplasmic reticulum kinase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

LIM kinase inhibitor
type: Class
subclass of: EC 2.7.* (P-containing group transferase) inhibitor
definition: An that interferes with the activity of any of the actin-binding kinases that phosphorylate members of the ADF/cofilin family of actin binding and filament severing proteins.
id: CHEBI:139074
has_related_synonym: LIM kinase inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

cis-Golgi ArfGEF GBF inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
id: CHEBI:139084
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

IP3 receptor agonist
type: Class
subclass of: agonist
definition: An agonist that activates IP3 receptors.
id: CHEBI:139109
has_related_synonym: D-myo-inositol 1,4,5-trisphosphate receptor agonist
has_related_synonym: D-myo-inositol 1,4,5-trisphosphate receptor agonists
has_related_synonym: IP3 agonist
has_related_synonym: IP3 agonists
has_related_synonym: IP3 receptor agonists
has_related_synonym: InsP3R agonist
has_related_synonym: InsP3R agonists
database_cross_reference: Wikipedia:Inositol_trisphosphate_receptor
has_obo_namespace: chebi_ontology
has_related_synonym: inositol trisphosphate receptor agonist
has_related_synonym: inositol trisphosphate receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

EC 2.4.1.255 (protein O-GlcNAc transferase) inhibitor
type: Class
subclass of: EC 2.4.1.* (hexosyltransferase) inhibitor
definition: An EC 2.4.1.* (hexosyltransferase) inhibitor that interferes with the action of protein O-GlcNAc transferase (EC 2.4.1.255).
id: CHEBI:139153
has_related_synonym: EC 2.4.1.255 (protein O-GlcNAc transferase) inhibitors
has_related_synonym: EC 2.4.1.255 inhibitor
has_related_synonym: EC 2.4.1.255 inhibitors
has_related_synonym: O-GlcNAc transferase inhibitor
has_related_synonym: O-GlcNAc transferase inhibitors
has_related_synonym: O-linked N-acetylglucosaminyltransferase inhibitor
has_related_synonym: O-linked N-acetylglucosaminyltransferase inhibitors
has_related_synonym: OGTase inhibitor
has_related_synonym: OGTase inhibitors
database_cross_reference: PMID:16231908
database_cross_reference: PMID:20640461
database_cross_reference: PMID:26862193
database_cross_reference: PMID:28032764
database_cross_reference: Patent:EP2438046
database_cross_reference: Patent:WO2010141074
has_related_synonym: UDP-N-acetyl-D-glucosamine:protein-O-beta-N-acetyl-D-glucosaminyl transferase inhibitor
has_related_synonym: UDP-N-acetyl-D-glucosamine:protein-O-beta-N-acetyl-D-glucosaminyl transferase inhibitors
database_cross_reference: Wikipedia:Protein_O-GlcNAc_transferase
has_obo_namespace: chebi_ontology
has_related_synonym: protein O-GlcNAc transferase (EC 2.4.1.255) inhibitor
has_related_synonym: protein O-GlcNAc transferase (EC 2.4.1.255) inhibitors
has_related_synonym: protein O-GlcNAc transferase inhibitor
has_related_synonym: protein O-GlcNAc transferase inhibitors
has_related_synonym: protein O-linked beta-N-acetylglucosamine transferase inhibitor
has_related_synonym: protein O-linked beta-N-acetylglucosamine transferase inhibitors
has_related_synonym: uridine diphospho-N-acetylglucosamine:polypeptide beta-N-acetylglucosaminyltransferase inhibitor
has_related_synonym: uridine diphospho-N-acetylglucosamine:polypeptide beta-N-acetylglucosaminyltransferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

melanin-concentrating hormone receptor antagonist
type: Class
subclass of: antagonist
definition: An antagonist that attaches to and blocks melanin-concentrating hormone receptors.
id: CHEBI:139155
has_related_synonym: MCHR agonist
has_related_synonym: MCHR agonists
database_cross_reference: PMID:16889232
database_cross_reference: PMID:17448659
database_cross_reference: Patent:US2012083489
database_cross_reference: Wikipedia:Melanin-concentrating_hormone_receptor
has_obo_namespace: chebi_ontology
has_related_synonym: melanin-concentrating hormone receptor antagonists
in_subset: 3 STAR
imported from: chebi.owl

nicotinic acid adenine dinucleotide phosphate receptor antagonist
type: Class
subclass of: antagonist
definition: An antagonist that attaches to and blocks nicotinic acid adenine dinucleotide phosphate receptors.
id: CHEBI:139180
has_related_synonym: NAADP antagonist
has_related_synonym: NAADP antagonists
has_related_synonym: NAADP receptor antagonist
has_related_synonym: NAADP receptor antagonists
database_cross_reference: PMID:21047915
has_obo_namespace: chebi_ontology
has_related_synonym: nicotinic acid adenine dinucleotide phosphate receptor antagonists
in_subset: 3 STAR
imported from: chebi.owl

peptide probe
type: Class
subclass of: probe
definition: A probe that is a small labelled and chemical active peptide which has been structurally modified for reacting with, for example, the beta-lactam moieties of various penicillin-type compounds.
id: CHEBI:139246
database_cross_reference: PMID:28987997
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 1.14.17.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen and with reduced ascorbate as one donor, and incorporation of one atom of oxygen) inhibitor
type: Class
subclass of: EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor
id: CHEBI:139338
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

EC 1.14.17.1 (dopamine beta-monooxygenase) inhibitor
type: Class
subclass of: EC 1.14.17.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen and with reduced ascorbate as one donor, and incorporation of one atom of oxygen) inhibitor
has_related_synonym: (3,4-dihydroxyphenethylamine)beta-mono-oxygenase inhibitor
has_related_synonym: (3,4-dihydroxyphenethylamine)beta-mono-oxygenase inhibitors
has_related_synonym: 3,4-dihydroxyphenethylamine beta-oxidase inhibitor
has_related_synonym: 3,4-dihydroxyphenethylamine beta-oxidase inhibitors
has_related_synonym: 3,4-dihydroxyphenethylamine,ascorbate:oxygen oxidoreductase (beta-hydroxylating) inhibitor
has_related_synonym: 3,4-dihydroxyphenethylamine,ascorbate:oxygen oxidoreductase (beta-hydroxylating) inhibitors
has_related_synonym: 4-(2-aminoethyl)pyrocatechol beta-oxidase inhibitor
has_related_synonym: 4-(2-aminoethyl)pyrocatechol beta-oxidase inhibitors
definition: An EC 1.14.17.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen and with reduced ascorbate as one donor, and incorporation of one atom of oxygen) inhibitor that interferes with the action of dopamine monooxygenase (EC 1.14.17.1).
id: CHEBI:139339
has_related_synonym: DbetaH inhibitor
has_related_synonym: DbetaH inhibitors
has_related_synonym: EC 1.14.17.1 (dopamine beta-monooxygenase) inhibitors
has_related_synonym: EC 1.14.17.1 inhibitor
has_related_synonym: EC 1.14.17.1 inhibitors
has_related_synonym: MDBH (membrane-associated dopamine beta-monooxygenase) inhibitor
has_related_synonym: MDBH (membrane-associated dopamine beta-monooxygenase) inhibitors
has_related_synonym: SDBH (soluble dopamine beta-monooxygenase) inhibitor
has_related_synonym: SDBH (soluble dopamine beta-monooxygenase) inhibitors
database_cross_reference: Wikipedia:Dopamine_beta-hydroxylase
has_obo_namespace: chebi_ontology
has_related_synonym: dopa beta-hydroxylase inhibitor
has_related_synonym: dopa beta-hydroxylase inhibitors
has_related_synonym: dopamine beta-hydroxylase inhibitor
has_related_synonym: dopamine beta-hydroxylase inhibitors
has_related_synonym: dopamine beta-monooxygenase (EC 1.14.17.1) inhibitor
has_related_synonym: dopamine beta-monooxygenase (EC 1.14.17.1) inhibitors
has_related_synonym: dopamine beta-monooxygenase inhibitor
has_related_synonym: dopamine beta-monooxygenase inhibitors
has_related_synonym: dopamine beta-oxidase inhibitor
has_related_synonym: dopamine beta-oxidase inhibitors
has_related_synonym: dopamine hydroxylase inhibitor
has_related_synonym: dopamine hydroxylase inhibitors
has_related_synonym: dopamine-B-hydroxylase inhibitor
has_related_synonym: dopamine-B-hydroxylase inhibitors
has_related_synonym: oxygenase, dopamine beta-mono-phenylamine beta-hydroxylase inhibitor
has_related_synonym: oxygenase, dopamine beta-mono-phenylamine beta-hydroxylase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

TRP channel blocker
type: Class
subclass of: TRP channel modulator
subclass of: membrane transport modulator
definition: An agent that inhibits the passage of cations through the transient receptor potential (TRP) channels.
id: CHEBI:139361
database_cross_reference: PMID:17445088
database_cross_reference: PMID:21198543
database_cross_reference: PMID:21607648
database_cross_reference: PMID:22308955
has_related_synonym: TRP channel blockers
database_cross_reference: Wikipedia:Transient_receptor_potential_channel
has_obo_namespace: chebi_ontology
has_related_synonym: transient receptor potential channel blocker
has_related_synonym: transient receptor potential channel blockers
in_subset: 3 STAR
imported from: chebi.owl

sensitiser
type: Class
subclass of: aetiopathogenetic role
definition: A chemical compound that causes a substantial proportion of exposed people or animals to develop an allergic reaction in normal tissue after repeated exposure to the compound.
id: CHEBI:139492
has_obo_namespace: chebi_ontology
has_related_synonym: sensitisers
has_related_synonym: sensitizer
has_related_synonym: sensitizers
in_subset: 3 STAR
imported from: chebi.owl

vitamin D receptor agonist
type: Class
subclass of: agonist
definition: An agonist that binds to and activates vitamin D receptors
id: CHEBI:139503
has_related_synonym: VDR agonist
has_related_synonym: VDR agonists
database_cross_reference: Wikipedia:Calcitriol_receptor
has_related_synonym: calcitriol receptor agonist
has_related_synonym: calcitriol receptor agonists
has_obo_namespace: chebi_ontology
has_related_synonym: vitamin D nuclear receptor agonist
has_related_synonym: vitamin D nuclear receptor agonists
has_related_synonym: vitamin D receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

EC 1.3.1.9 [enoyl-[acyl-carrier-protein] reductase (NADH)] inhibitor
type: Class
subclass of: EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor
definition: An EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of enoyl-[acyl-carrier-protein] reductase (NADH), EC 1.3.1.9.
id: CHEBI:139512
has_related_synonym: EC 1.3.1.9 [enoyl-[acyl-carrier-protein] reductase (NADH)] inhibitors
has_related_synonym: EC 1.3.1.9 inhibitor
has_related_synonym: EC 1.3.1.9 inhibitors
has_related_synonym: ENR inhibitor
has_related_synonym: ENR inhibitors
has_related_synonym: NADH-enoyl acyl carrier protein reductase inhibitor
has_related_synonym: NADH-enoyl acyl carrier protein reductase inhibitors
has_related_synonym: NADH-specific enoyl-ACP reductase inhibitor
has_related_synonym: NADH-specific enoyl-ACP reductase inhibitors
database_cross_reference: Wikipedia:Enoyl-acyl_carrier_protein_reductase
has_related_synonym: acyl-[acyl-carrier-protein]:NAD+ oxidoreductase inhibitor
has_related_synonym: acyl-[acyl-carrier-protein]:NAD+ oxidoreductase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: enoyl-ACP reductase inhibitor
has_related_synonym: enoyl-ACP reductase inhibitors
has_related_synonym: enoyl-[acyl carrier protein] reductase inhibitor
has_related_synonym: enoyl-[acyl carrier protein] reductase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 4.1.1.17 (ornithine decarboxylase) inhibitor
type: Class
subclass of: EC 4.1.1.* (carboxy-lyase) inhibitor
definition: An EC 4.1.1.* (carboxy-lyase) inhibitor that interferes with the action of ornithine decarboxylase (EC 4.1.1.17).
id: CHEBI:139556
has_related_synonym: EC 4.1.1.17 (ornithine decarboxylase) inhibitors
has_related_synonym: EC 4.1.1.17 inhibitor
has_related_synonym: EC 4.1.1.17 inhibitors
has_related_synonym: L-ornithine carboxy-lyase (putrescine-forming) inhibitor
has_related_synonym: L-ornithine carboxy-lyase (putrescine-forming) inhibitors
has_related_synonym: L-ornithine carboxy-lyase inhibitor
has_related_synonym: L-ornithine carboxy-lyase inhibitors
has_related_synonym: ODC inhibitor
has_related_synonym: ODC inhibitors
has_related_synonym: SpeC inhibitor
has_related_synonym: SpeC inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

Jacobaea metabolite
type: Class
subclass of: plant metabolite
definition: Any plant metabolite that is produced by the genus Jacobaea.
id: CHEBI:139566
has_related_synonym: Jacobaea metabolites
database_cross_reference: Wikipedia:Jacobaea
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

lysophosphatidic acid receptor 3 agonist
type: Class
subclass of: agonist
definition: An agonist that binds to and activates lysophosphatidic acid 3 receptors.
id: CHEBI:139584
has_related_synonym: LPA3 agonist
has_related_synonym: LPA3 agonists
has_related_synonym: LPAR3 agonist
has_related_synonym: LPAR3 agonists
database_cross_reference: Wikipedia:LPAR3
has_obo_namespace: chebi_ontology
has_related_synonym: lysophosphatidic acid receptor 3 agonists
in_subset: 3 STAR
imported from: chebi.owl

survivin suppressant
type: Class
subclass of: apoptosis inducer
definition: An apoptosis inducer that works by selectively inhibiting survivin (BIRC5) gene promoter activity so as to down-regulate survivin, a protein that inhibits apoptosis, so leading to induction of apoptosis.
id: CHEBI:139609
has_obo_namespace: chebi_ontology
has_related_synonym: survivin suppressants
has_related_synonym: survivin suppressor
has_related_synonym: survivin suppressors
in_subset: 3 STAR
imported from: chebi.owl

TRPV4 agonist
type: Class
subclass of: agonist
definition: An agonist at the transient receptor potential vanilloid 4 (TRPV4).
id: CHEBI:140061
has_related_synonym: OSM9-like transient receptor potential channel, member 4 agonist
has_related_synonym: OSM9-like transient receptor potential channel, member 4 agonists
has_related_synonym: OTRPC4 agonist
has_related_synonym: OTRPC4 agonists
has_related_synonym: TRPV4 agonists
has_related_synonym: VR-OAC agonist
has_related_synonym: VR-OAC agonists
database_cross_reference: Wikipedia:TRPV4
has_obo_namespace: chebi_ontology
has_related_synonym: transient receptor potential +agonist
has_related_synonym: transient receptor potential cation channel subfamily V member 4 agonist
has_related_synonym: transient receptor potential cation channel subfamily V member 4 agonists
has_related_synonym: transient receptor potential vanilloid 4 agonists
has_related_synonym: transient receptor vanilloid-4 agonist
has_related_synonym: transient receptor vanilloid-4 agonists
has_related_synonym: vanilloid-receptor related osmotically activated channel agonist
has_related_synonym: vanilloid-receptor related osmotically activated channel agonists
in_subset: 3 STAR
imported from: chebi.owl

Camellia sinensis metabolite
type: Class
subclass of: plant metabolite
definition: Any plant metabolite that is produced by Camellia sinensis.
has_related_synonym: C. sinensis metabolite
has_related_synonym: C. sinensis metabolites
id: CHEBI:140160
has_related_synonym: Camellia sinensis metabolites
database_cross_reference: Wikipedia:Camellia_sinensis
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

Brassica napus metabolite
type: Class
subclass of: plant metabolite
definition: Any plant metabolite that is produced by rapeseed (Brassica napus).
has_related_synonym: Brassica napus metabolites
id: CHEBI:140165
database_cross_reference: Wikipedia:Rapeseed
has_obo_namespace: chebi_ontology
has_related_synonym: rapeseed metabolite
has_related_synonym: rapeseed metabolites
in_subset: 3 STAR
imported from: chebi.owl

calcium-dependent antibiotics
type: Class
subclass of: antimicrobial agent
definition: Any antimicrobial agent whose activity is dependent on the presence of calcium ions.
id: CHEBI:140190
has_related_synonym: Ca(2+)-dependent antibiotic
has_related_synonym: Ca(2+)-dependent antibiotics
has_related_synonym: Ca-dependent antibiotic
has_related_synonym: Ca-dependent antibiotics
database_cross_reference: PMID:18489906
database_cross_reference: PMID:22711659
database_cross_reference: PMID:29108098
database_cross_reference: PMID:29434326
has_related_synonym: calcium-dependent antibiotic
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 1.1.1.37 (malate dehydrogenase) inhibitor
type: Class
subclass of: EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor
has_related_synonym: (S)-malate:NAD(+) oxidoreductase inhibitor
has_related_synonym: (S)-malate:NAD(+) oxidoreductase inhibitors
definition: An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of any malate dehydrogenase (EC 1.1.1.37).
id: CHEBI:140378
has_related_synonym: EC 1.1.1.37 (malate dehydrogenase) inhibitors
has_related_synonym: EC 1.1.1.37 inhibitor
has_related_synonym: EC 1.1.1.37 inhibitors
has_related_synonym: L-malate dehydrogenase inhibitor
has_related_synonym: L-malate dehydrogenase inhibitors
has_related_synonym: L-malate-NAD(+) oxidoreductase inhibitor
has_related_synonym: L-malate-NAD(+) oxidoreductase inhibitors
has_related_synonym: MDH inhibitor
has_related_synonym: MDH inhibitors
has_related_synonym: NAD-L-malate dehydrogenase inhibitor
has_related_synonym: NAD-L-malate dehydrogenase inhibitors
has_related_synonym: NAD-dependent malate dehydrogenase inhibitor
has_related_synonym: NAD-dependent malate dehydrogenase inhibitors
has_related_synonym: NAD-dependent malic dehydrogenase inhibitor
has_related_synonym: NAD-dependent malic dehydrogenase inhibitors
has_related_synonym: NAD-linked malate dehydrogenase inhibitor
has_related_synonym: NAD-linked malate dehydrogenase inhibitors
has_related_synonym: NAD-malate dehydrogenase inhibitor
has_related_synonym: NAD-malate dehydrogenase inhibitors
has_related_synonym: NAD-malic dehydrogenase inhibitor
has_related_synonym: NAD-malic dehydrogenase inhibitors
has_related_synonym: NAD-specific malate dehydrogenase inhibitor
has_related_synonym: NAD-specific malate dehydrogenase inhibitors
database_cross_reference: PMID:559534
database_cross_reference: Wikipedia:Malate_dehydrogenase
has_obo_namespace: chebi_ontology
has_related_synonym: malate (NAD) dehydrogenase inhibitor
has_related_synonym: malate (NAD) dehydrogenase inhibitors
has_related_synonym: malate dehydrogenase (EC 1.1.1.37) inhibitor
has_related_synonym: malate dehydrogenase (EC 1.1.1.37) inhibitors
has_related_synonym: malate dehydrogenase inhibitor
has_related_synonym: malate dehydrogenase inhibitors
has_related_synonym: malic acid dehydrogenase inhibitor
has_related_synonym: malic acid dehydrogenase inhibitors
has_related_synonym: malic dehydrogenase inhibitor
has_related_synonym: malic dehydrogenase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

specialised pro-resolving mediator
type: Class
subclass of: biological role
subclass of: signalling molecule
subclass of: anti-inflammatory agent
definition: A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation.
id: CHEBI:140399
has_related_synonym: SPM
has_related_synonym: SPMs
database_cross_reference: Wikipedia:Specialized_pro-resolving_mediators
has_obo_namespace: chebi_ontology
has_related_synonym: specialised pro-resolving mediators
has_related_synonym: specialised proresolving mediator
has_related_synonym: specialised proresolving mediators
has_related_synonym: specialized pro-resolving mediator
has_related_synonym: specialized pro-resolving mediators
has_related_synonym: specialized proresolving mediator
has_related_synonym: specialized proresolving mediators
in_subset: 3 STAR
imported from: chebi.owl

neurokinin-3 receptor antagonist
type: Class
subclass of: antagonist
definition: An antagonist at the neurokinin-3 receptor.
id: CHEBI:140482
has_related_synonym: NK-3 receptor antagonist
has_related_synonym: NK-3 receptor antagonists
has_related_synonym: NK3 receptor antagonist
has_related_synonym: NK3 receptor antagonists
has_related_synonym: NK3R antagonist
has_related_synonym: NK3R antagonists
database_cross_reference: PMID:25107588
has_related_synonym: TACR3 antagonist
has_related_synonym: TACR3 antagonists
database_cross_reference: Wikipedia:Tachykinin_receptor_3
has_obo_namespace: chebi_ontology
has_related_synonym: neurokinin-3 receptor antagonists
has_related_synonym: tachykinin receptor 3 antagonist
has_related_synonym: tachykinin receptor 3 antagonists
in_subset: 3 STAR
imported from: chebi.owl

tropomyosin-related kinase B receptor agonist
type: Class
subclass of: agonist
definition: An agonist that binds to and deactivates the tropomyosin-related kinase B (TrkB) receptor, the main signaling receptor of the neurotrophin brain-derived neurotrophic factor (BDNF).
id: CHEBI:140489
has_related_synonym: TrkB receptor agonist
has_related_synonym: TrkB receptor agonists
database_cross_reference: Wikipedia:Tropomyosin_receptor_kinase_B
has_obo_namespace: chebi_ontology
has_related_synonym: tropomyosin-related kinase B receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

TRPV1 agonist
type: Class
subclass of: agonist
definition: An agonist at the transient receptor potential vanilloid 1 (TRPV1).
id: CHEBI:140535
has_related_synonym: TRPV1 agonists
database_cross_reference: Wikipedia:TRPV1
has_related_synonym: capsaicin receptor agonist
has_related_synonym: capsaicin receptor agonists
has_obo_namespace: chebi_ontology
has_related_synonym: transient receptor potential cation channel subfamily V member 1 agonist
has_related_synonym: transient receptor potential cation channel subfamily V member 1 agonists
has_related_synonym: transient receptor potential vanilloid 1 agonist
has_related_synonym: transient receptor potential vanilloid 1 agonists
has_related_synonym: vanilloid receptor 1 agonist
has_related_synonym: vanilloid receptor 1 agonists
in_subset: 3 STAR
imported from: chebi.owl

Arabidopsis thaliana metabolite
type: Class
subclass of: plant metabolite
definition: Any plant metabolite that is produced by Arabidopsis thaliana.
has_related_synonym: Arabidopsis thaliana metabolites
id: CHEBI:140602
database_cross_reference: Wikipedia:Arabidopsis_thaliana
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

secreted frizzled-related protein 1 inhibitor
type: Class
subclass of: inhibitor
definition: Any inhibitor of secreted frizzled-related protein 1 (SFRP1). The level of SFRP1 affects osteoblast apoptosis and proliferation, so SFRP1 inhibitors have the potential to be used for the treatment of osteoporosis or other bone related disorders.
id: CHEBI:140701
database_cross_reference: PMID:19053830
database_cross_reference: PMID:19819694
has_related_synonym: SFRP1 inhibitor
has_related_synonym: SFRP1 inhibitors
database_cross_reference: Wikipedia:Secreted_frizzled-related_protein_1
has_obo_namespace: chebi_ontology
has_related_synonym: sFRP-1 inhibitor
has_related_synonym: sFRP-1 inhibitors
has_related_synonym: secreted frizzled-related protein 1 inhibitors
has_related_synonym: secreted frizzled-related protein-1 inhibitor
has_related_synonym: secreted frizzled-related protein-1 inhibitors
in_subset: 3 STAR
imported from: chebi.owl

Hedgehog signaling pathway inhibitor
type: Class
subclass of: pathway inhibitor
definition: Any pathway inhibitor that inhibits the Hedgehog signalling pathway.
id: CHEBI:140921
has_related_synonym: Hedgehog pathway inhibitor
has_related_synonym: Hedgehog pathway inhibitors
has_related_synonym: Hedgehog signaling pathway inhibitors
database_cross_reference: Wikipedia:Hedgehog_pathway_inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

glioma-associated oncogene inhibitor
type: Class
subclass of: inhibitor
definition: An inhibitor of any of the glioma-associated oncogene (GLI) proteins.
id: CHEBI:140922
has_related_synonym: GLI inhibitor
has_related_synonym: GLI inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: glioma-associated oncogene inhibitors
in_subset: 3 STAR
imported from: chebi.owl

neuropeptide FF receptor antagonist
type: Class
subclass of: antagonist
definition: An antagonist that binds to and deactivates neuropeptide FF receptors.
id: CHEBI:140982
has_related_synonym: NPFF receptor antagonist
has_related_synonym: NPFF receptor antagonists
has_related_synonym: NPFFR antagonist
has_related_synonym: NPFFR antagonists
database_cross_reference: PMID:26896564
database_cross_reference: Wikipedia:Neuropeptide_FF
has_obo_namespace: chebi_ontology
has_related_synonym: neuropeptide FF receptor antagonists
in_subset: 3 STAR
imported from: chebi.owl

neuropeptide FF receptor agonist
type: Class
subclass of: agonist
definition: An agonist that activates neuropeptide FF (NPFF) receptors.
id: CHEBI:141000
has_related_synonym: NPFF receptor agonist
has_related_synonym: NPFF receptor agonists
database_cross_reference: PMID:26896564
database_cross_reference: Wikipedia:Neuropeptide_FF
has_obo_namespace: chebi_ontology
has_related_synonym: neuropeptide FF receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

kisspeptin receptor agonist
type: Class
subclass of: agonist
definition: An agonist that acts at the kisspeptin receptor (KISS1R).
id: CHEBI:141001
database_cross_reference: Wikipedia:KiSS1-derived_peptide_receptor
has_obo_namespace: chebi_ontology
has_related_synonym: kisspeptin receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

quinone outside inhibitor
type: Class
subclass of: fungicide
subclass of: mitochondrial cytochrome-bc1 complex inhibitor
definition: A mitochondrial cytochrome-bc1 complex inhibitor that acts at the Quinone 'outer' (Qo) binding site of the cytochrome-bc1 complex.
id: CHEBI:141153
has_related_synonym: QOI
has_related_synonym: QOIs
has_related_synonym: Qo inhibitor
has_related_synonym: Qo inhibitors
database_cross_reference: Wikipedia:QoI
has_obo_namespace: chebi_ontology
has_related_synonym: quinone outside inhibitors
in_subset: 3 STAR
imported from: chebi.owl

pronematicide
type: Class
subclass of: propesticide
subclass of: nematicide
definition: A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active nematicide for which it is a pronematicide.
id: CHEBI:141301
has_obo_namespace: chebi_ontology
has_related_synonym: pronematicides
has_related_synonym: pronematocide
has_related_synonym: pronematocides
in_subset: 3 STAR
imported from: chebi.owl

5-hydroxytryptamine 2B receptor agonist
type: Class
subclass of: agonist
has_related_synonym: 5-HT2B agonist
has_related_synonym: 5-HT2B agonists
has_related_synonym: 5-HT2B receptor agonist
has_related_synonym: 5-HT2B receptor agonists
has_related_synonym: 5-hydroxytryptamine 2B receptor agonists
has_related_synonym: 5-hydroxytryptamine receptor 2B agonist
has_related_synonym: 5-hydroxytryptamine receptor 2B agonists
definition: An agonist at the 5-hydroxytryptamine 2B (5-HT2B) receptor.
id: CHEBI:142184
has_obo_namespace: chebi_ontology
has_related_synonym: serotonin receptor 2B agonist
has_related_synonym: serotonin receptor 2B agonists
in_subset: 3 STAR
imported from: chebi.owl

5-hydroxytryptamine 2C receptor agonist
type: Class
subclass of: agonist
has_related_synonym: 5-HT2C receptor agonist
has_related_synonym: 5-HT2C receptor agonists
has_related_synonym: 5-HT2c agonist
has_related_synonym: 5-HT2c agonists
has_related_synonym: 5-hydroxytryptamine 2C receptor agonists
has_related_synonym: 5-hydroxytryptamine receptor 2C agonist
has_related_synonym: 5-hydroxytryptamine receptor 2C agonists
definition: An agonist at the 5-hydroxytryptamine 2B (5-HT2C) receptor.
id: CHEBI:142185
has_obo_namespace: chebi_ontology
has_related_synonym: serotonin receptor 2C agonist
has_related_synonym: serotonin receptor 2C agonists
in_subset: 3 STAR
imported from: chebi.owl

EC 1.14.14.94 (leukotriene-B4 20-monooxygenase) inhibitor
type: Class
subclass of: EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor
has_related_synonym: (6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (20-hydroxylating) inhibitor
has_related_synonym: (6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (20-hydroxylating) inhibitors
definition: Any EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor that interferes with the action of leukotriene-B4 20-monooxygenase (EC 1.14.14.94).
id: CHEBI:142480
has_related_synonym: CYP4F2 inhibitor
has_related_synonym: CYP4F2 inhibitors
has_related_synonym: CYP4F3 inhibitor
has_related_synonym: CYP4F3 inhibitors
has_related_synonym: EC 1.14.13.30 inhibitor
has_related_synonym: EC 1.14.13.30 inhibitors
has_related_synonym: EC 1.14.14.94 (leukotriene-B4 20-monooxygenase) inhibitors
has_related_synonym: EC 1.14.14.94 inhibitor
has_related_synonym: EC 1.14.14.94 inhibitors
has_related_synonym: LTB4 20-hydroxylase inhibitor
has_related_synonym: LTB4 20-hydroxylase inhibitors
has_related_synonym: LTB4 omega-hydroxylase inhibitor
has_related_synonym: LTB4 omega-hydroxylase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: leucotriene-B4 omega-hydroxylase inhibitor
has_related_synonym: leucotriene-B4 omega-hydroxylase inhibitors
has_related_synonym: leukotriene-B4 20-hydroxylase inhibitor
has_related_synonym: leukotriene-B4 20-hydroxylase inhibitors
has_related_synonym: leukotriene-B4 20-monooxygenase (EC 1.14.14.94) inhibitors
has_related_synonym: leukotriene-B4 20-monooxygenase inhibitor
has_related_synonym: leukotriene-B4 20-monooxygenase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.14.15.3 (alkane 1-monooxygenase) inhibitor
type: Class
subclass of: EC 1.14.15.* (oxidoreductase acting on paired donors, with reduced Fe-S protein as one donor, incorporating 1 O atom) inhibitor
has_related_synonym: 1-hydroxylase inhibitor
has_related_synonym: 1-hydroxylase inhibitors
definition: Any EC 1.14.15.* (oxidoreductase acting on paired donors, with reduced Fe-S protein as one donor, incorporating 1 O atom) inhibitor that interferes with the action of alkane 1-monooxygenase (EC 1.14.15.3).
id: CHEBI:142481
has_related_synonym: EC 1.14.15.3 (alkane 1-monooxygenase) inhibitors
has_related_synonym: EC 1.14.15.3 inhibitor
has_related_synonym: EC 1.14.15.3 inhibitors
has_related_synonym: alkane 1-hydroxylase inhibitor
has_related_synonym: alkane 1-hydroxylase inhibitors
has_related_synonym: alkane 1-monooxygenase (EC 1.14.15.3) inhibitor
has_related_synonym: alkane 1-monooxygenase (EC 1.14.15.3) inhibitors
has_related_synonym: alkane 1-monooxygenase inhibitor
has_related_synonym: alkane 1-monooxygenase inhibitors
has_related_synonym: alkane hydroxylase inhibitor
has_related_synonym: alkane hydroxylase inhibitors
has_related_synonym: alkane monooxygenase inhibitor
has_related_synonym: alkane monooxygenase inhibitors
has_related_synonym: alkane,reduced-rubredoxin:oxygen 1-oxidoreductase inhibitor
has_related_synonym: alkane,reduced-rubredoxin:oxygen 1-oxidoreductase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: fatty acid omega-hydroxylase inhibitor
has_related_synonym: fatty acid omega-hydroxylase inhibitors
has_related_synonym: omega-hydroxylase inhibitor
has_related_synonym: omega-hydroxylase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 4.1.1.15 (glutamate decarboxylase) inhibitor
type: Class
subclass of: EC 4.1.1.* (carboxy-lyase) inhibitor
definition: An EC 4.1.1.* (carboxy-lyase) inhibitor that interferes with the action of glutamate decarboxylase (EC 4.1.1.15).
id: CHEBI:142581
has_related_synonym: EC 4.1.1.15 (glutamate decarboxylase) inhibitors
has_related_synonym: EC 4.1.1.15 inhibitor
has_related_synonym: EC 4.1.1.15 inhibitors
has_related_synonym: L-aspartate-alpha-decarboxylase inhibitor
has_related_synonym: L-aspartate-alpha-decarboxylase inhibitors
has_related_synonym: L-glutamate 1-carboxy-lyase (4-aminobutanoate-forming) inhibitor
has_related_synonym: L-glutamate 1-carboxy-lyase (4-aminobutanoate-forming) inhibitors
has_related_synonym: L-glutamate 1-carboxy-lyase inhibitor
has_related_synonym: L-glutamate 1-carboxy-lyase inhibitors
has_related_synonym: L-glutamate alpha-decarboxylase inhibitor
has_related_synonym: L-glutamate alpha-decarboxylase inhibitors
has_related_synonym: L-glutamic acid decarboxylase inhibitor
has_related_synonym: L-glutamic acid decarboxylase inhibitors
has_related_synonym: L-glutamic decarboxylase inhibitor
has_related_synonym: L-glutamic decarboxylase inhibitors
database_cross_reference: Wikipedia:Glutamate_decarboxylase
has_related_synonym: aspartate 1-decarboxylase inhibitor
has_related_synonym: aspartate 1-decarboxylase inhibitors
has_related_synonym: aspartic alpha-decarboxylase inhibitor
has_related_synonym: aspartic alpha-decarboxylase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: cysteic acid decarboxylase inhibitor
has_related_synonym: cysteic acid decarboxylase inhibitors
has_related_synonym: gamma-glutamate decarboxylase inhibitor
has_related_synonym: gamma-glutamate decarboxylase inhibitors
has_related_synonym: glutamate decarboxylase (EC 4.1.1.15) inhibitor
has_related_synonym: glutamate decarboxylase (EC 4.1.1.15) inhibitors
has_related_synonym: glutamate decarboxylase inhibitor
has_related_synonym: glutamate decarboxylase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

tau aggregation inhibitor
type: Class
subclass of: inhibitor
definition: A chemical that inhibits the aggregation of the tau protein (HGNC:MAPT) and its distinct morphological forms (e.g. paired helical fragments (PHFs), straight filaments (SFs), oligomers, or larger aggregates).
id: CHEBI:142738
database_cross_reference: PMID:19164903
database_cross_reference: PMID:19189357
database_cross_reference: PMID:20149808
database_cross_reference: PMID:23484434
database_cross_reference: PMID:24072703
database_cross_reference: PMID:25387336
database_cross_reference: PMID:26809554
database_cross_reference: PMID:27975248
has_related_synonym: TAI
database_cross_reference: Wikipedia:Tau_protein
has_obo_namespace: chebi_ontology
has_exact_synonym: tau aggregation inhibitor
has_related_synonym: tau aggregation inhibitors
has_related_synonym: tau protein aggregation inhibitor
has_related_synonym: tau protein aggregation inhibitors
has_related_synonym: tau-aggregation inhibitor
has_related_synonym: tau-aggregation inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.5.1.117 (homogentisate solanesyltransferase) inhibitor
type: Class
subclass of: EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor
id: CHEBI:142781
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

TRPV channel modulator
type: Class
subclass of: TRP channel modulator
definition: Any transient receptor potential (TRP) channel modulator that modulates the TRPV channels (V = vanilloid). There is strong evidence that action at one or more of this class of proteins is responsible for the insecticidal action of pymetrozine, pyrifluquinazon, and afidopyropen.
id: CHEBI:142782
has_related_synonym: TRPV channel modulators
has_obo_namespace: chebi_ontology
has_related_synonym: transient receptor potential (vanilloid) channel modulator
has_related_synonym: transient receptor potential (vanilloid) channel modulators
in_subset: 3 STAR
imported from: chebi.owl

TRP channel modulator
type: Class
subclass of: membrane transport modulator
definition: An agent that modulates the passage of cations through the transient receptor potential (TRP) channels.
id: CHEBI:142783
has_related_synonym: TRP channel modulators
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 3.3.2.10 (soluble epoxide hydrolase) inhibitor
type: Class
subclass of: EC 3.3.* (ether hydrolase) inhibitor
definition: Any inhibitor of soluble epoxide hydrolase, a bifunctional enzyme that in humans is encoded by the EPHX2 gene.Found in both the cytosol and peroxisomes it binds to specific epoxides and converts them into the corresponding diols.
id: CHEBI:142790
has_obo_namespace: chebi_ontology
has_related_synonym: sEHi
has_related_synonym: soluble epoxide hydrolase inhibitor
has_related_synonym: soluble epoxide hydrolase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

GABAB receptor agonist
type: Class
subclass of: GABA agonist
id: CHEBI:143001
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

EC 2.1.3.* (carboxy- and carbamoyltransferases) inhibitor
type: Class
subclass of: EC 2.1.* (C1-transferase) inhibitor
definition: An EC 2.1.* (C1-transferase) inhibitor that interferes with the action of any carboxy- and carbamoyltransferases (EC 2.1.3.*).
id: CHEBI:143002
has_related_synonym: EC 2.1.3.* (carboxy- and carbamoyltransferases) inhibitors
has_related_synonym: EC 2.1.3.* (carboxytransferase and carbamoyltransferase) inhibitor
has_related_synonym: EC 2.1.3.* (carboxytransferase and carbamoyltransferase) inhibitors
has_related_synonym: EC 2.1.3.* inhibitor
has_related_synonym: EC 2.1.3.* inhibitors
has_related_synonym: carboxy- and carbamoyltransferase (EC 2.1.3.*) inhibitor
has_related_synonym: carboxy- and carbamoyltransferase (EC 2.1.3.*) inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 2.1.3.3 (ornithine carbamoyltransferase) inhibitor
type: Class
subclass of: EC 2.1.3.* (carboxy- and carbamoyltransferases) inhibitor
definition: Any EC 2.1.3.* (carboxy- and carbamoyltransferases) inhibitor that inhibits the action of ornithine carbamoyltransferase (EC 2.1.3.3).
id: CHEBI:143003
has_related_synonym: EC 2.1.3.3 (ornithine carbamoyltransferase) inhibitors
has_related_synonym: EC 2.1.3.3 inhibitor
has_related_synonym: EC 2.1.3.3 inhibitors
has_related_synonym: L-ornithine carbamoyltransferase inhibitor
has_related_synonym: L-ornithine carbamoyltransferase inhibitors
has_related_synonym: L-ornithine carbamyltransferase inhibitor
has_related_synonym: L-ornithine carbamyltransferase inhibitors
has_related_synonym: L-ornithine transcarbamylase inhibitor
has_related_synonym: L-ornithine transcarbamylase inhibitors
has_related_synonym: OTC inhibitor
has_related_synonym: OTC inhibitors
has_related_synonym: carbamoyl-phosphate:L-ornithine carbamoyltransferase inhibitor
has_related_synonym: carbamoyl-phosphate:L-ornithine carbamoyltransferase inhibitors
has_related_synonym: carbamylphosphate-ornithine transcarbamylase inhibitor
has_related_synonym: carbamylphosphate-ornithine transcarbamylase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: citrulline phosphorylase inhibitor
has_related_synonym: citrulline phosphorylase inhibitors
has_related_synonym: ornithine carbamoyltransferase (EC 2.1.3.3) inhibitor
has_related_synonym: ornithine carbamoyltransferase (EC 2.1.3.3) inhibitors
has_related_synonym: ornithine carbamoyltransferase inhibitor
has_related_synonym: ornithine carbamoyltransferase inhibitors
has_related_synonym: ornithine carbamyltransferase inhibitor
has_related_synonym: ornithine carbamyltransferase inhibitors
has_related_synonym: ornithine transcarbamylase inhibitor
has_related_synonym: ornithine transcarbamylase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

impurity
type: Class
subclass of: chemical role
definition: A chemical role played by any unwanted chemical substance inside a confined amount of liquid, gas, or solid, which differs from the chemical composition of the material or compound. For example, an impurity can be an undesired by-product of a chemical reaction or manufacturing process, a drug contaminant, or can be created upon degradation during storage.
id: CHEBI:143130
database_cross_reference: Wikipedia:Impurity
has_obo_namespace: chebi_ontology
has_related_synonym: contaminant
has_related_synonym: contaminants
has_related_synonym: impurities
has_exact_synonym: impurity
in_subset: 3 STAR
imported from: chebi.owl

peptide allergen
type: Class
subclass of: allergen
definition: Any peptide which causes the onset of an allergic reaction.
id: CHEBI:143204
database_cross_reference: PMID:12531657
database_cross_reference: PMID:13966695
database_cross_reference: PMID:2045614
database_cross_reference: PMID:6423971
database_cross_reference: PMID:6681826
database_cross_reference: PMID:7549111
database_cross_reference: Patent:EP0650976
database_cross_reference: Patent:WO9404572
has_related_synonym: allergenic peptide
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

carbohydrate allergen
type: Class
subclass of: allergen
definition: Any carbohydrate, carbohydrate derivative or derived substituent group which causes the onset of an allergic reaction.
id: CHEBI:143231
database_cross_reference: PMID:9788708
has_related_synonym: allergenic carbohydrate
has_related_synonym: allergenic carbohydrate derivative
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

ceramide allergen
type: Class
subclass of: allergen
definition: Any ceramide which causes the onset of an allergic reaction.
id: CHEBI:143252
has_related_synonym: allergenic ceramide
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 1.14.14.154 (sterol 14alpha-demethylase) inhibitor
type: Class
subclass of: EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor
definition: Any EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor that interferes with the action of sterol 14alpha-demethylase (EC 1.14.14.154).
id: CHEBI:143828
has_related_synonym: CYP51 inhibitor
has_related_synonym: CYP51 inhibitors
has_related_synonym: EC 1.14.14.154 (sterol 14alpha-demethylase) inhibitors
has_related_synonym: EC 1.14.14.154 inhibitor
has_related_synonym: EC 1.14.14.154 inhibitors
has_related_synonym: ERG11 inhibitor
has_related_synonym: ERG11 inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: cytochrome P450 51 inhibitor
has_related_synonym: cytochrome P450 51 inhibitors
has_related_synonym: lanosterol 14-demethylase inhibitor
has_related_synonym: lanosterol 14-demethylase inhibitors
has_related_synonym: lanosterol 14alpha-demethylase inhibitor
has_related_synonym: lanosterol 14alpha-demethylase inhibitors
has_related_synonym: obtusufoliol 14-demethylase inhibitor
has_related_synonym: obtusufoliol 14-demethylase inhibitors
has_related_synonym: oxidoreductase (14-methyl cleaving) inhibitors
has_related_synonym: sterol 14-demethylase inhibitor
has_related_synonym: sterol 14-demethylase inhibitors
has_related_synonym: sterol 14alpha-demethylase (EC 1.14.14.154) inhibitor
has_related_synonym: sterol 14alpha-demethylase (EC 1.14.14.154) inhibitors
has_related_synonym: sterol 14alpha-demethylase inhibitor
has_related_synonym: sterol 14alpha-demethylase inhibitors
has_related_synonym: sterol,[reduced NADPH--hemoprotein reductase]:oxygen inhibitor
has_related_synonym: sterol,[reduced NADPH--hemoprotein reductase]:oxygen oxidoreductase (14-methyl cleaving) inhibitor
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.1.40 (pyruvate kinase) inhibitor
type: Class
subclass of: EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor
definition: An EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor that interferes with the action of pyruvate kinase (EC 2.7.1.40).
id: CHEBI:143909
has_related_synonym: EC 2.7.1.40 inhibitor
has_related_synonym: EC 2.7.1.40 inhibitors
database_cross_reference: Wikipedia:Pyruvate_kinase
has_obo_namespace: chebi_ontology
has_related_synonym: phosphoenol transphosphorylase inhibitor
has_related_synonym: phosphoenol transphosphorylase inhibitors
has_related_synonym: phosphoenolpyruvate kinase inhibitor
has_related_synonym: phosphoenolpyruvate kinase inhibitors
has_related_synonym: pyruvate kinase inhibitor
has_related_synonym: pyruvate kinase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.14.15.6 cholesterol monooxygenase (side-chain-cleaving) inhibitor
type: Class
subclass of: EC 1.14.15.* (oxidoreductase acting on paired donors, with reduced Fe-S protein as one donor, incorporating 1 O atom) inhibitor
definition: Any EC 1.14.15.* (oxidoreductase acting on paired donors, with reduced Fe-S protein as one donor, incorporating 1 O atom) inhibitor that interferes with the action of cholesterol monooxygenase (side-chain-cleaving) (EC 1.14.15.6).
has_related_synonym: C27-side chain cleavage enzyme inhibitor
has_related_synonym: C27-side chain cleavage enzyme inhibitors
id: CHEBI:144064
has_related_synonym: EC 1.14.15.6 inhibitor
has_related_synonym: EC 1.14.15.6 inhibitors
database_cross_reference: Wikipedia:Cholesterol_side-chain_cleavage_enzyme
has_obo_namespace: chebi_ontology
has_related_synonym: cholesterol 20-22-desmolase inhibitor
has_related_synonym: cholesterol 20-22-desmolase inhibitors
has_related_synonym: cholesterol C20-22 desmolase inhibitor
has_related_synonym: cholesterol C20-22 desmolase inhibitors
has_related_synonym: cholesterol desmolase inhibitor
has_related_synonym: cholesterol desmolase inhibitors
has_related_synonym: cholesterol monooxygenase (side-chain-cleaving) inhibitor
has_related_synonym: cholesterol monooxygenase (side-chain-cleaving) inhibitors
has_related_synonym: cholesterol side-chain cleavage enzyme inhibitor
has_related_synonym: cholesterol side-chain cleavage enzyme inhibitors
has_related_synonym: cholesterol side-chain-cleaving enzyme inhibitor
has_related_synonym: cholesterol side-chain-cleaving enzyme inhibitors
has_related_synonym: cytochrome P-450scc inhibitor
has_related_synonym: cytochrome P-450scc inhibitors
has_related_synonym: steroid 20-22 desmolase inhibitor
has_related_synonym: steroid 20-22 desmolase inhibitors
has_related_synonym: steroid 20-22-lyase inhibitor
has_related_synonym: steroid 20-22-lyase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.4.3.2 (L-amino-acid oxidase) inhibitor
type: Class
subclass of: EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor
definition: Any EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor that interferes with the action of L-amino-acid oxidase (EC 1.4.3.2).
id: CHEBI:144097
has_related_synonym: EC 1.4.3.2 (L-amino-acid oxidase) inhibitors
has_related_synonym: EC 1.4.3.2 inhibitor
has_related_synonym: EC 1.4.3.2 inhibitors
has_related_synonym: L-amino-acid oxidase inhibitor
has_related_synonym: L-amino-acid oxidase inhibitor (EC 1.4.3.2) inhibitor
has_related_synonym: L-amino-acid oxidase inhibitor (EC 1.4.3.2) inhibitors
has_related_synonym: L-amino-acid oxidase inhibitors
has_related_synonym: L-amino-acid:oxygen oxidoreductase (deaminating) inhibitor
has_related_synonym: L-amino-acid:oxygen oxidoreductase (deaminating) inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: ophio-amino-acid oxidase inhibitor
has_related_synonym: ophio-amino-acid oxidase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.6.1.2 (alanine transaminase) inhibitor
type: Class
subclass of: EC 2.6.1.* (transaminase) inhibitor
id: CHEBI:144099
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

EC 2.7.1.105 (6-phosphofructo-2-kinase) inhibitor
type: Class
subclass of: EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor
has_related_synonym: (6-phosphofructo-2-kinase) inhibitors
has_related_synonym: 6-phosphofructo-2-kinase (phosphorylating) inhibitor
has_related_synonym: 6-phosphofructo-2-kinase (phosphorylating) inhibitors
has_related_synonym: 6-phosphofructo-2-kinase inhibitor
has_related_synonym: 6-phosphofructo-2-kinase inhibitors
has_related_synonym: 6-phosphofructose 2-kinase inhibitor
has_related_synonym: 6-phosphofructose 2-kinase inhibitors
definition: An EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor that interferes with the action of 6-phosphofructo-2-kinase (EC 2.7.1.105).
id: CHEBI:144387
has_related_synonym: EC 2.7.1.105 inhibitor
has_related_synonym: EC 2.7.1.105 inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: fructose 6-phosphate 2-kinase inhibitor
has_related_synonym: fructose 6-phosphate 2-kinase inhibitors
has_related_synonym: phosphofructokinase 2 inhibitor
has_related_synonym: phosphofructokinase 2 inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.1.1.64 (retinoid isomerohydrolase) inhibitor
type: Class
subclass of: EC 3.1.1.* (carboxylic ester hydrolase) inhibitor
definition: An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of retinoid isomerohydrolase (EC 3.1.1.64).
id: CHEBI:144455
has_related_synonym: EC 3.1.1.64 (retinoid isomerohydrolase) inhibitors
has_related_synonym: EC 3.1.1.64 inhibitor
has_related_synonym: EC 3.1.1.64 inhibitors
has_related_synonym: RPE65 inhibitor
has_related_synonym: RPE65 inhibitors
database_cross_reference: Wikipedia:RPE65
has_related_synonym: all-trans-retinol isomerase:hydrolase inhibitor
has_related_synonym: all-trans-retinol isomerase:hydrolase inhibitors
has_related_synonym: all-trans-retinyl-palmitate hydrolase inhibitor
has_related_synonym: all-trans-retinyl-palmitate hydrolase inhibitors
has_related_synonym: all-trans-retinylester 11-cis isomerohydrolase inhibitor
has_related_synonym: all-trans-retinylester 11-cis isomerohydrolase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: retinoid isomerohydrolase inhibitor
has_related_synonym: retinoid isomerohydrolase inhibitors
has_related_synonym: retinol isomerase inhibitor
has_related_synonym: retinol isomerase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

tumour antigen
type: Class
subclass of: antigen
definition: An antigenic substance produced in tumour cells, which triggers an immune response in the host.
id: CHEBI:144829
database_cross_reference: Wikipedia:Tumor_antigen
has_obo_namespace: chebi_ontology
has_related_synonym: tumour antigens
in_subset: 3 STAR
imported from: chebi.owl

C5a receptor antagonist
type: Class
subclass of: G-protein-coupled receptor antagonist
definition: Any antagonist of the C5a receptor.
has_related_synonym: C5AR1 antagonist
has_related_synonym: C5AR1 antagonists
has_related_synonym: C5a receptor antagonists
has_related_synonym: CD88 antagonist
has_related_synonym: CD88 antagonists
id: CHEBI:144895
database_cross_reference: PMID:20004096
database_cross_reference: PMID:23537791
database_cross_reference: PMID:24117111
database_cross_reference: PMID:25682062
database_cross_reference: PMID:26634479
database_cross_reference: PMID:28955891
database_cross_reference: PMID:29802264
database_cross_reference: PMID:29867214
database_cross_reference: Wikipedia:C5a_receptor
has_obo_namespace: chebi_ontology
has_related_synonym: cluster of differentiation 88 antagonist
has_related_synonym: cluster of differentiation 88 antagonists
has_related_synonym: complement component 5a receptor 1 antagonist
has_related_synonym: complement component 5a receptor 1 antagonists
in_subset: 3 STAR
imported from: chebi.owl

EC 3.6.5.2 (small monomeric GTPase) inhibitor
type: Class
subclass of: EC 3.6.5.* (hydrolases acting on GTP; involved in cellular and subcellular movement) inhibitor
id: CHEBI:144981
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

sphingosine-1-phosphate receptor antagonist
type: Class
subclass of: antagonist
definition: An antagonist that binds to and blocks sphingosine 1-phosphate receptors, a class of G protein-coupled receptors that are targets of the lipid signalling molecule sphingosine-1-phosphate (S1P).
id: CHEBI:144987
has_related_synonym: EDG receptor antagonist
has_related_synonym: S1P receptor antagonist
has_related_synonym: S1P receptor antagonists
has_related_synonym: SIP antagonist
has_related_synonym: SIP antagonists
has_obo_namespace: chebi_ontology
has_related_synonym: sphingosine 1-phosphate receptor antagonist
has_related_synonym: sphingosine 1-phosphate receptor antagonists
has_related_synonym: sphingosine-1-phosphate receptor antagonists
in_subset: 3 STAR
imported from: chebi.owl

sphingosine-1-phosphate receptor 3 antagonist
type: Class
subclass of: sphingosine-1-phosphate receptor antagonist
definition: Any sphingosine-1-phosphate receptor (S1PR) antagonist that acts as an antagonist towards the subtype 3 receptors (S1PR3).
id: CHEBI:144997
database_cross_reference: PMID:25910934
database_cross_reference: PMID:26943364
database_cross_reference: PMID:30587459
database_cross_reference: PMID:30793318
database_cross_reference: PMID:30972941
database_cross_reference: PMID:31502430
has_related_synonym: S1PR3 antagonist
has_related_synonym: S1PR3 antagonists
has_obo_namespace: chebi_ontology
has_related_synonym: sphingosine-1-phosphate receptor 3 antagonists
in_subset: 3 STAR
imported from: chebi.owl

sphingosine-1-phosphate receptor 1 antagonist
type: Class
subclass of: sphingosine-1-phosphate receptor antagonist
definition: Any sphingosine-1-phosphate receptor (S1PR) antagonist that acts as an antagonist for the subtype 1 receptors (S1PR1).
id: CHEBI:144998
database_cross_reference: PMID:20823564
database_cross_reference: PMID:21798372
database_cross_reference: PMID:22214363
database_cross_reference: PMID:26291341
has_related_synonym: S1PR1 antagonist
has_related_synonym: S1PR1 antagonists
has_obo_namespace: chebi_ontology
has_related_synonym: sphingosine-1-phosphate receptor 1 antagonists
in_subset: 3 STAR
imported from: chebi.owl

antispermatogenic agent
type: Class
subclass of: application
definition: An agent that destroy spermatozoa in the male genitalia and block spermatogenesis.
id: CHEBI:145047
database_cross_reference: PMID:16371305
has_related_synonym: antispermatogenic
has_related_synonym: antispermatogenic agents
has_related_synonym: antispermatogenics
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

hyaluronan synthesis inhibitor
type: Class
subclass of: inhibitor
definition: Any inhibitor that interferes with the synthesis of hyaluronic acid (HA, also known as hyaluronan).
id: CHEBI:145253
has_related_synonym: HA synthesis inhibitor
has_related_synonym: HA synthesis inhibitors
database_cross_reference: PMID:15373776
database_cross_reference: PMID:19444760
database_cross_reference: PMID:20332231
database_cross_reference: PMID:23288481
database_cross_reference: PMID:23426189
database_cross_reference: PMID:24141285
database_cross_reference: PMID:25537799
database_cross_reference: PMID:27706810
has_obo_namespace: chebi_ontology
has_related_synonym: hyaluronan synthesis inhibitors
has_related_synonym: hyaluronic acid synthesis inhibitor
has_related_synonym: hyaluronic acid synthesis inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.1.1.42 (isocitrate dehydrogenase) inhibitor
type: Class
subclass of: EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor
definition: An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of any isocitrate dehydrogenase (EC 1.1.1.42).
id: CHEBI:145410
has_related_synonym: EC 1.1.1.42 inhibitor
has_related_synonym: EC 1.1.1.42 inhibitors
has_related_synonym: IDH inhibitor
has_related_synonym: IDH inhibitors
has_related_synonym: IDP inhibitor
has_related_synonym: IDP inhibitors
has_related_synonym: IDP1 inhibitor
has_related_synonym: IDP1 inhibitors
has_related_synonym: IDP2 inhibitor
has_related_synonym: IDP2 inhibitors
has_related_synonym: IDP3 inhibitor
has_related_synonym: IDP3 inhibitors
has_related_synonym: NADP isocitric dehydrogenase inhibitor
has_related_synonym: NADP isocitric dehydrogenase inhibitors
has_related_synonym: NADP(+)-ICDH inhibitor
has_related_synonym: NADP(+)-ICDH inhibitors
has_related_synonym: NADP(+)-IDH inhibitor
has_related_synonym: NADP(+)-IDH inhibitors
has_related_synonym: NADP(+)-linked isocitrate dehydrogenase inhibitor
has_related_synonym: NADP(+)-linked isocitrate dehydrogenase inhibitors
has_related_synonym: NADP-dependent isocitrate dehydrogenase inhibitor
has_related_synonym: NADP-dependent isocitrate dehydrogenase inhibitors
has_related_synonym: NADP-dependent isocitric dehydrogenase inhibitor
has_related_synonym: NADP-dependent isocitric dehydrogenase inhibitors
has_related_synonym: NADP-linked isocitrate dehydrogenase inhibitor
has_related_synonym: NADP-linked isocitrate dehydrogenase inhibitors
has_related_synonym: NADP-specific isocitrate dehydrogenase inhibitor
has_related_synonym: NADP-specific isocitrate dehydrogenase inhibitors
database_cross_reference: Wikipedia:Isocitrate_dehydrogenase
has_obo_namespace: chebi_ontology
has_related_synonym: dual-cofactor-specific isocitrate dehydrogenase inhibitor
has_related_synonym: dual-cofactor-specific isocitrate dehydrogenase inhibitors
has_related_synonym: isocitrate (NADP) dehydrogenase inhibitor
has_related_synonym: isocitrate (NADP) dehydrogenase inhibitors
has_related_synonym: isocitrate (nicotinamide adenine dinucleotide phosphate) dehydrogenase inhibitor
has_related_synonym: isocitrate (nicotinamide adenine dinucleotide phosphate) dehydrogenase inhibitors
has_related_synonym: isocitrate dehydrogenase (NADP(+)) inhibitor
has_related_synonym: isocitrate dehydrogenase (NADP(+)) inhibitors
has_related_synonym: isocitrate dehydrogenase (NADP-dependent) inhibitor
has_related_synonym: isocitrate dehydrogenase (NADP-dependent) inhibitors
has_related_synonym: isocitrate dehydrogenase inhibitor
has_related_synonym: isocitrate dehydrogenase inhibitors
has_related_synonym: oxalosuccinate decarboxylase inhibitor
has_related_synonym: oxalosuccinate decarboxylase inhibitors
has_related_synonym: oxalsuccinic decarboxylase inhibitor
has_related_synonym: oxalsuccinic decarboxylase inhibitors
has_related_synonym: triphosphopyridine nucleotide-linked isocitrate dehydrogenase-oxalosuccinate carboxylase inhibitor
has_related_synonym: triphosphopyridine nucleotide-linked isocitrate dehydrogenase-oxalosuccinate carboxylase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.11.21 (polo kinase) inhibitor
type: Class
subclass of: EC 2.7.11.* (protein-serine/threonine kinase) inhibitor
definition: An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of any polo kinase (EC 2.7.11.21).
id: CHEBI:145425
has_related_synonym: Cdc5 inhibitor
has_related_synonym: Cdc5 inhibitors
has_related_synonym: Cdc5p inhibitor
has_related_synonym: Cdc5p inhibitors
has_related_synonym: EC 2.7.11.21 (polo kinase) inhibitors
has_related_synonym: EC 2.7.11.21 inhibitor
has_related_synonym: EC 2.7.11.21 inhibitors
has_related_synonym: PLK inhibitor
has_related_synonym: PLK inhibitors
has_related_synonym: Plk inhibitor
has_related_synonym: Plk inhibitors
has_related_synonym: Plk1 inhibitor
has_related_synonym: Plk1 inhibitors
has_related_synonym: Plo1 inhibitor
has_related_synonym: Plo1 inhibitors
has_related_synonym: STK21 inhibitor
has_related_synonym: STK21 inhibitors
database_cross_reference: Wikipedia:Polo_kinase
has_obo_namespace: chebi_ontology
has_related_synonym: polo kinase inhibitor
has_related_synonym: polo kinase inhibitors
has_related_synonym: polo serine-threonine kinase inhibitor
has_related_synonym: polo serine-threonine kinase inhibitors
has_related_synonym: polo-like kinase 1 inhibitor
has_related_synonym: polo-like kinase 1 inhibitors
has_related_synonym: polo-like kinase inhibitor
has_related_synonym: polo-like kinase inhibitors
has_related_synonym: serine/threonine-specific Drosophila kinase polo inhibitor
has_related_synonym: serine/threonine-specific Drosophila kinase polo inhibitors
in_subset: 3 STAR
imported from: chebi.owl

uncoupling protein inhibitor
type: Class
subclass of: inhibitor
definition: Any inhibitor that acts on uncoupling protein.
id: CHEBI:145437
database_cross_reference: PMID:22420157
database_cross_reference: PMID:23008094
database_cross_reference: PMID:23609063
database_cross_reference: PMID:24904988
database_cross_reference: PMID:28089824
database_cross_reference: PMID:29858912
database_cross_reference: Patent:US2009258064
database_cross_reference: Patent:US7510710
has_related_synonym: UCP inhibitor
has_related_synonym: UCP inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: mitochondrial uncoupling protein inhibitor
has_related_synonym: mitochondrial uncoupling protein inhibitors
has_related_synonym: uncoupling protein inhibitors
in_subset: 3 STAR
imported from: chebi.owl

C-X-C chemokine receptor type 4 antagonist
type: Class
subclass of: antagonist
definition: An antogonist that blocks C-X-C chemokine receptor type 4 (CXCR-4).
has_related_synonym: C-X-C chemokine receptor type 4 antagonists
has_related_synonym: C-X-C motif chemokine receptor 4 antagonist
has_related_synonym: C-X-C motif chemokine receptor 4 antagonists
has_related_synonym: CD184 antagonist
has_related_synonym: CD184 antagonists
id: CHEBI:145438
has_related_synonym: CXCR-4 antagonist
has_related_synonym: CXCR-4 antagonists
has_related_synonym: CXCR4 antagonist
has_related_synonym: CXCR4 antagonists
database_cross_reference: Wikipedia:CXCR4
has_obo_namespace: chebi_ontology
has_related_synonym: chemokine (C-X-C motif) receptor 4 antagonist
has_related_synonym: chemokine (C-X-C motif) receptor 4 antagonists
has_related_synonym: fusin antagonist
has_related_synonym: fusin antagonists
in_subset: 3 STAR
imported from: chebi.owl

GABAA receptor antagonist
type: Class
subclass of: GABA antagonist
id: CHEBI:145515
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

forkhead box protein O1 inhibitor
type: Class
subclass of: inhibitor
definition: Any inhibitor that acts on forkhead box protein O1 (FOXO1).
id: CHEBI:145807
has_related_synonym: FOXO1 inhibitor
has_related_synonym: FOXO1 inhibitors
has_related_synonym: Foxo1 inhibitor
has_related_synonym: Foxo1 inhibitors
database_cross_reference: PMID:20655898
database_cross_reference: PMID:26239835
database_cross_reference: PMID:28653156
has_obo_namespace: chebi_ontology
has_related_synonym: forkhead box protein O1 inhibitors
has_related_synonym: forkhead in rhabdomyosarcoma inhibitor
has_related_synonym: forkhead in rhabdomyosarcoma inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.2.1.11 (aspartate-semialdehyde dehydrogenase) inhibitor
type: Class
subclass of: EC 1.2.1.* (oxidoreductase acting on donor aldehyde/oxo group with NAD(+) or NADP(+) as acceptor) inhibitor
has_related_synonym: ASA dehydrogenase inhibitor
has_related_synonym: ASA dehydrogenase inhibitors
definition: Any EC 1.2.1.* (oxidoreductase acting on donor aldehyde/oxo group with NAD(+) or NADP(+) as acceptor) inhibitor that inhibits the action of aspartate-semialdehyde dehydrogenase (EC 1.2.1.11).
id: CHEBI:145814
has_related_synonym: EC 1.2.1.11 (aspartate-semialdehyde dehydrogenase) inhibitors
has_related_synonym: EC 1.2.1.11 inhibitor
has_related_synonym: EC 1.2.1.11 inhibitors
has_related_synonym: L-aspartate-4-semialdehyde:NADP+ oxidoreductase (phosphorylating) inhibitor
has_related_synonym: L-aspartate-4-semialdehyde:NADP+ oxidoreductase (phosphorylating) inhibitors
has_related_synonym: L-aspartate-beta-semialdehyde:NADP oxidoreductase (phosporylating) inhibitor
has_related_synonym: L-aspartate-beta-semialdehyde:NADP oxidoreductase (phosporylating) inhibitors
database_cross_reference: PMID:14726201
database_cross_reference: PMID:26404410
database_cross_reference: Wikipedia:Aspartate-semialdehyde_dehydrogenase
has_related_synonym: aspartate semialdehyde dehydrogenase inhibitor
has_related_synonym: aspartate semialdehyde dehydrogenase inhibitors
has_related_synonym: aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) inhibitor
has_related_synonym: aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) inhibitors
has_related_synonym: aspartate-semialdehyde dehydrogenase inhibitor
has_related_synonym: aspartate-semialdehyde dehydrogenase inhibitors
has_related_synonym: aspartic beta-semialdehyde dehydrogenase inhibitor
has_related_synonym: aspartic beta-semialdehyde dehydrogenase inhibitors
has_related_synonym: aspartic semialdehyde dehydrogenase inhibitor
has_related_synonym: aspartic semialdehyde dehydrogenase inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

antiatherosclerotic agent
type: Class
subclass of: cardiovascular drug
definition: A cardiovascular drug that prevents atherosclerosis (a disease in which the inside of an artery narrows due to the build up of plaque). Compare with antiatherogenic agent.
id: CHEBI:145947
has_related_synonym: anti-atherosclerotic agent
has_related_synonym: anti-atherosclerotic agents
has_related_synonym: anti-atherosclerotic drug
has_related_synonym: anti-atherosclerotic drugs
has_exact_synonym: antiatherosclerotic agent
has_related_synonym: antiatherosclerotic agents
has_related_synonym: antiatherosclerotic drug
has_related_synonym: antiatherosclerotic drugs
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

5-hydroxytryptamine 2A receptor agonist
type: Class
subclass of: agonist
has_related_synonym: 5-HT2A agonist
has_related_synonym: 5-HT2A agonists
has_related_synonym: 5-HT2A receptor agonist
has_related_synonym: 5-HT2A receptor agonists
has_related_synonym: 5-hydroxytryptamine 2A receptor agonists
has_related_synonym: 5-hydroxytryptamine receptor 2A agonist
has_related_synonym: 5-hydroxytryptamine receptor 2A agonists
definition: An agonist at the 5-hydroxytryptamine 2A (5-HT2A) receptor.
id: CHEBI:145982
has_obo_namespace: chebi_ontology
has_related_synonym: serotonin receptor 2A agonist
has_related_synonym: serotonin receptor 2A agonists
in_subset: 3 STAR
imported from: chebi.owl

ryanoid insecticide
type: Class
subclass of: insecticide
subclass of: ryanodine receptor modulator
id: CHEBI:146222
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

ryanodine receptor antagonist
type: Class
subclass of: ryanodine receptor modulator
id: CHEBI:146223
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

CB2 receptor agonist
type: Class
subclass of: cannabinoid receptor agonist
definition: A cannabinoid receptor agonist that binds to and activates type 2 cannabinoid receptors.
has_exact_synonym: CB2 receptor agonist
has_related_synonym: CB2 receptor agonists
has_related_synonym: CB2R agonist
has_related_synonym: CB2R agonists
id: CHEBI:146246
database_cross_reference: Wikipedia:Cannabinoid_receptor_type_2
has_related_synonym: cannabinoid receptor 2 agonist
has_related_synonym: cannabinoid receptor 2 agonists
has_related_synonym: cannabinoid receptor type 2 agonist
has_related_synonym: cannabinoid receptor type 2 agonists
has_obo_namespace: chebi_ontology
has_related_synonym: type 2 cannabinoid receptor agonist
has_related_synonym: type 2 cannabinoid receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

oneirogen
type: Class
subclass of: psychotropic drug
definition: Any substance that produces or enhances dream-like states of consciousness.
id: CHEBI:146270
database_cross_reference: Wikipedia:Oneirogen
has_obo_namespace: chebi_ontology
has_related_synonym: oneirogens
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor
type: Class
subclass of: EC 3.4.22.* (cysteine endopeptidase) inhibitor
has_related_synonym: 3C-like protease inhibitor
has_related_synonym: 3C-like protease inhibitors
has_related_synonym: 3cLpro inhibitor
has_related_synonym: 3cLpro inhibitors
definition: An EC 3.4.22.* (cysteine endopeptidase) inhibitor that interferes with the action of SARS coronavirus main proteinase (EC 3.4.22.69).
id: CHEBI:147285
has_related_synonym: EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitors
has_related_synonym: EC 3.4.22.69 inhibitor
has_related_synonym: EC 3.4.22.69 inhibitors
has_related_synonym: Mpro inhibitor
has_related_synonym: Mpro inhibitors
has_related_synonym: SARS 3C-like protease inhibitor
has_related_synonym: SARS 3C-like protease inhibitors
has_related_synonym: SARS coronavirus 3CL protease inhibitor
has_related_synonym: SARS coronavirus 3CL protease inhibitors
has_related_synonym: SARS coronavirus main peptidase inhibitor
has_related_synonym: SARS coronavirus main peptidase inhibitors
has_related_synonym: SARS coronavirus main protease inhibitor
has_related_synonym: SARS coronavirus main protease inhibitors
has_related_synonym: SARS coronavirus main proteinase inhibitor
has_related_synonym: SARS coronavirus main proteinase inhibitors
has_related_synonym: SARS-CoV 3CLpro enzyme inhibitor
has_related_synonym: SARS-CoV 3CLpro enzyme inhibitors
has_related_synonym: SARS-CoV Mpro inhibitor
has_related_synonym: SARS-CoV Mpro inhibitors
has_related_synonym: SARS-CoV main protease inhibitor
has_related_synonym: SARS-CoV main protease inhibitors
database_cross_reference: Wikipedia:C30_Endopeptidase
has_obo_namespace: chebi_ontology
has_related_synonym: coronavirus 3C-like protease inhibitor
has_related_synonym: coronavirus 3C-like protease inhibitors
has_related_synonym: severe acute respiratory syndrome coronavirus main protease inhibitor
has_related_synonym: severe acute respiratory syndrome coronavirus main protease inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.17.23 (angiotensin-converting enzyme 2) inhibitor
type: Class
subclass of: EC 3.4.17* (metallocarboxypeptidase) inhibitor
has_related_synonym: ACE-2 inhibitor
has_related_synonym: ACE-2 inhibitors
has_related_synonym: ACE2 inhibitor
has_related_synonym: ACE2 inhibitors
definition: Any EC 3.4.17.* (metallocarboxypeptidase) inhibitor that inhibits the action of angiotensin-converting enzyme 2 (EC 3.4.17.23).
id: CHEBI:147289
has_exact_synonym: EC 3.4.17.23 (angiotensin-converting enzyme 2) inhibitor
has_related_synonym: EC 3.4.17.23 (angiotensin-converting enzyme 2) inhibitors
has_related_synonym: EC 3.4.17.23 inhibitor
has_related_synonym: EC 3.4.17.23 inhibitors
database_cross_reference: Wikipedia:Angiotensin-converting_enzyme_2
has_related_synonym: angiotensin converting enzyme 2 inhibitor
has_related_synonym: angiotensin converting enzyme 2 inhibitors
has_related_synonym: angiotensin converting enzyme-2 inhibitor
has_related_synonym: angiotensin converting enzyme-2 inhibitors
has_related_synonym: angiotensin-converting enzyme 2 inhibitor
has_related_synonym: angiotensin-converting enzyme 2 inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: hACE2 inhibitor
has_related_synonym: hACE2 inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.17* (metallocarboxypeptidase) inhibitor
type: Class
subclass of: EC 3.4.* (hydrolases acting on peptide bond) inhibitor
definition: Any EC 3.4.* (hydrolases acting on peptide bond) inhibitor that inhibits the action of a metallocarboxypeptidase (EC 3.4.17.*).
id: CHEBI:147290
has_exact_synonym: EC 3.4.17* (metallocarboxypeptidase) inhibitor
has_related_synonym: EC 3.4.17* (metallocarboxypeptidase) inhibitors
has_related_synonym: EC 3.4.17.* inhibitor
has_related_synonym: EC 3.4.17.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: metallocarboxypeptidase inhibitor
has_related_synonym: metallocarboxypeptidase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

nitrification inhibitor
type: Class
subclass of: inhibitor
definition: Any inhibitor added to nitrogen fertilizers which can reduce the rate at which ammonium is converted to nitrate. Under appropriate conditions, this can help reduce nitrogen losses through denitrification and leaching.
id: CHEBI:148436
database_cross_reference: Wikipedia:Nitrification
has_obo_namespace: chebi_ontology
has_related_synonym: nitrification inhibitors
in_subset: 3 STAR
imported from: chebi.owl

spin trapping reagent
type: Class
subclass of: reagent
definition: A reagent used in electron paramagnetic resonance (EPR) spectroscopy to react covalently with radical products whose half-life is be too short to detect. The resulting adducts are more stable enabling their paramagnetic resonance spectra to be obtained.
id: CHEBI:149497
database_cross_reference: Wikipedia:Spin_trapping
has_obo_namespace: chebi_ontology
has_related_synonym: spin trap
has_related_synonym: spin trapping reagents
has_related_synonym: spin traps
in_subset: 3 STAR
imported from: chebi.owl

emetic
type: Class
subclass of: drug
definition: Any agent that induces nausea and vomiting.
id: CHEBI:149552
has_obo_namespace: chebi_ontology
has_related_synonym: emetics
in_subset: 3 STAR
imported from: chebi.owl

anticoronaviral agent
type: Class
subclass of: antiviral agent
definition: Any antiviral agent which inhibits the activity of coronaviruses.
id: CHEBI:149553
database_cross_reference: Wikipedia:Coronavirus
has_related_synonym: anti-coronaviral agent
has_related_synonym: anti-coronaviral agents
has_related_synonym: anti-coronavirus agent
has_related_synonym: anti-coronavirus agents
has_exact_synonym: anticoronaviral agent
has_related_synonym: anticoronaviral agents
has_related_synonym: anticoronaviral drug
has_related_synonym: anticoronaviral drugs
has_related_synonym: anticoronavirus agent
has_related_synonym: anticoronavirus agents
has_related_synonym: anticoronviral agent
has_related_synonym: anticoronviral agents
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 2.3.3.8 (ATP citrate synthase) inhibitor
type: Class
subclass of: EC 2.3.3.* (acyltransferase converting acyl to alkyl group on transfer) inhibitor
has_related_synonym: ATP citrate (pro-S)-lyase inhibitor
has_related_synonym: ATP citrate (pro-S)-lyase inhibitors
has_related_synonym: ATP citrate lyase inhibitor
has_related_synonym: ATP citrate lyase inhibitors
has_related_synonym: ATP citrate synthase inhibitor
has_related_synonym: ATP citrate synthase inhibitors
has_related_synonym: ATP-citric lyase inhibitor
has_related_synonym: ATP-citric lyase inhibitors
has_related_synonym: ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO(-)->acetyl-CoA] (ATP-dephosphorylating) inhibitor
has_related_synonym: ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO(-)->acetyl-CoA] (ATP-dephosphorylating) inhibitors
definition: An EC 2.3.3.* (acyltransferase converting acyl to alkyl group on transfer) inhibitor that interferes with the action of ATP citrate synthase (EC 2.3.3.8).
id: CHEBI:149598
has_exact_synonym: EC 2.3.3.8 (ATP citrate synthase) inhibitor
has_related_synonym: EC 2.3.3.8 (ATP citrate synthase) inhibitors
has_related_synonym: EC 2.3.3.8 inhibitor
has_related_synonym: EC 2.3.3.8 inhibitors
database_cross_reference: Wikipedia:ATP_citrate_synthase
has_related_synonym: acetyl-CoA:oxaloacetate acetyltransferase (isomerizing, ADP-phosphorylating) inhibitor
has_related_synonym: acetyl-CoA:oxaloacetate acetyltransferase (isomerizing, ADP-phosphorylating) inhibitors
has_related_synonym: adenosine triphosphate citrate lyase inhibitor
has_related_synonym: adenosine triphosphate citrate lyase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: citrate cleavage enzyme inhibitor
has_related_synonym: citrate cleavage enzyme inhibitors
has_related_synonym: citrate-ATP lyase inhibitor
has_related_synonym: citrate-ATP lyase inhibitors
has_related_synonym: citric cleavage enzyme inhibitor
has_related_synonym: citric cleavage enzyme inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.21.36 (pancreatic elastase) inhibitor
type: Class
subclass of: EC 3.4.21.* (serine endopeptidase) inhibitor
definition: An EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the activity of pancreatic elastase (EC 3.4.21.36).
id: CHEBI:149639
has_related_synonym: EC 3.4.21.36 (pancreatic elastase) inhibitors
has_related_synonym: EC 3.4.21.36 inhibitor
has_related_synonym: EC 3.4.21.36 inhibitors
database_cross_reference: Wikipedia:Pancreatic_elastase
has_obo_namespace: chebi_ontology
has_related_synonym: elastase inhibitor
has_related_synonym: elastase inhibitors
has_related_synonym: elaszym inhibitor
has_related_synonym: elaszym inhibitors
has_related_synonym: pancreatic elastase (EC 3.4.21.36) inhibitor
has_related_synonym: pancreatic elastase (EC 3.4.21.36) inhibitors
has_related_synonym: pancreatic elastase I inhibitor
has_related_synonym: pancreatic elastase I inhibitors
has_related_synonym: pancreatic elastase inhibitor
has_related_synonym: pancreatic elastase inhibitors
has_related_synonym: pancreatopeptidase E inhibitor
has_related_synonym: pancreatopeptidase E inhibitors
has_related_synonym: serine elastase inhibitor
has_related_synonym: serine elastase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

chemokine receptor 2 antagonist
type: Class
subclass of: antagonist
definition: An antogonist that blocks chemokine receptor 2 (CCR2).
has_related_synonym: C-C chemokine receptor type 2 antagonist
has_related_synonym: C-C chemokine receptor type 2 antagonists
has_related_synonym: CCR-2 antagonist
has_related_synonym: CCR-2 antagonists
has_related_synonym: CCR2 antagonist
has_related_synonym: CCR2 antagonists
has_related_synonym: CD192 antagonist
has_related_synonym: CD192 antagonists
id: CHEBI:149711
has_related_synonym: CKR-2B antagonist
has_related_synonym: CKR-2B antagonists
database_cross_reference: Wikipedia:CCR2
has_obo_namespace: chebi_ontology
has_related_synonym: chemokine receptor 2 antagonists
in_subset: 3 STAR
imported from: chebi.owl

SERCA activator
type: Class
subclass of: enzyme activator
definition: Any compound that activates Sarcoplasmic/Endoplasmic Reticulum Calcium-ATPase (EC 7.2.2.10).
id: CHEBI:150006
has_related_synonym: EC 7.2.2.10 activator
has_related_synonym: EC 7.2.2.10 activators
has_related_synonym: SERCA activators
has_related_synonym: Sarcoplasmic/Endoplasmic Reticulum Calcium-ATPase activator
has_related_synonym: Sarcoplasmic/Endoplasmic Reticulum Calcium-ATPase activators
database_cross_reference: Wikipedia:SERCA
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

electron donor
type: Class
subclass of: donor
definition: A molecular entity that can transfer an electron to another molecular entity.
id: CHEBI:15022
has_related_synonym: Elektronendonator
has_obo_namespace: chebi_ontology
has_related_synonym: donneur d'electron
has_exact_synonym: electron donor
in_subset: 3 STAR
imported from: chebi.owl

acceptor
type: Class
subclass of: chemical role
has_related_synonym: A
definition: A molecular entity that can accept an electron, a pair of electrons, an atom or a group from another molecular entity.
has_exact_synonym: Acceptor
has_related_synonym: Akzeptor
has_alternative_id: CHEBI:13699
id: CHEBI:15339
has_alternative_id: CHEBI:2377
has_related_synonym: Hydrogen-acceptor
database_cross_reference: KEGG:C00028
database_cross_reference: KEGG:C16722
has_related_synonym: Oxidized donor
has_related_synonym: accepteur
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

topoisomerase II inhibitor
type: Class
subclass of: topoisomerase inhibitor
definition: A topoisomerase inhibitor that inhibits DNA topoisomerase II.
id: CHEBI:156203
has_obo_namespace: chebi_ontology
has_related_synonym: topoisomerase II inhibitors
in_subset: 3 STAR
imported from: chebi.owl

MAIT cell agonist
type: Class
subclass of: agonist
definition: An agonist that selectively binds to and activates mucosal associated invariant T cells (MAIT cells).
id: CHEBI:156211
has_related_synonym: MAIT cell agonists
has_obo_namespace: chebi_ontology
has_related_synonym: mucosal associated invariant T cell agonist
has_related_synonym: mucosal associated invariant T cell agonists
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.21.75 (furin) inhibitor
type: Class
subclass of: EC 3.4.21.* (serine endopeptidase) inhibitor
definition: An EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of furin (EC 3.4.21.75).
id: CHEBI:156297
has_related_synonym: EC 3.4.21.75 (furin) inhibitors
has_related_synonym: EC 3.4.21.75 inhibitor
has_related_synonym: EC 3.4.21.75 inhibitors
has_related_synonym: PACE inhibitor
has_related_synonym: PACE inhibitors
has_related_synonym: PC1 inhibitor
has_related_synonym: PC1 inhibitors
has_related_synonym: SPC3 inhibitor
has_related_synonym: SPC3 inhibitors
database_cross_reference: Wikipedia:Furin
has_obo_namespace: chebi_ontology
has_related_synonym: dibasic processing enzyme inhibitor
has_related_synonym: dibasic processing enzyme inhibitors
has_related_synonym: furin convertase inhibitor
has_related_synonym: furin convertase inhibitors
has_related_synonym: furin inhibitor
has_related_synonym: furin inhibitors
has_related_synonym: paired basic amino acid cleaving enzyme inhibitor
has_related_synonym: paired basic amino acid cleaving enzyme inhibitors
has_related_synonym: paired basic amino acid converting enzyme inhibitor
has_related_synonym: paired basic amino acid converting enzyme inhibitors
has_related_synonym: prohormone convertase inhibitor
has_related_synonym: prohormone convertase inhibitors
has_related_synonym: proprotein convertase inhibitor
has_related_synonym: proprotein convertase inhibitors
has_related_synonym: serine proteinase PACE inhibitor
has_related_synonym: serine proteinase PACE inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.4.1.109 (dolichyl-phosphate-mannose-protein mannosyltransferase) inhibitor
type: Class
subclass of: EC 2.4.1.* (hexosyltransferase) inhibitor
definition: An EC 2.4.1.* (hexosyltransferase) inhibitor that interferes with the action of dolichyl-phosphate-mannose-protein mannosyltransferase (EC 2.4.1.109).
id: CHEBI:156527
has_related_synonym: EC 2.4.1.109 (dolichyl-phosphate-mannose-protein mannosyltransferase) inhibitors
has_related_synonym: EC 2.4.1.109 inhibitor
has_related_synonym: EC 2.4.1.109 inhibitors
has_related_synonym: PMT inhibitor
has_related_synonym: PMT inhibitors
database_cross_reference: Wikipedia:Dolichyl-phosphate-mannose-protein_mannosyltransferase
has_obo_namespace: chebi_ontology
has_related_synonym: dolichol phosphomannose-protein mannosyltransferase inhibitor
has_related_synonym: dolichol phosphomannose-protein mannosyltransferase inhibitors
has_related_synonym: dolichyl-D-mannosyl-phosphate:protein O-D-mannosyltransferase inhibitor
has_related_synonym: dolichyl-D-mannosyl-phosphate:protein O-D-mannosyltransferase inhibitors
has_related_synonym: dolichyl-phosphate-D-mannose:protein O-D-mannosyltransferase inhibitor
has_related_synonym: dolichyl-phosphate-D-mannose:protein O-D-mannosyltransferase inhibitors
has_related_synonym: dolichyl-phosphate-mannose--protein mannosyltransferase inhibitor
has_related_synonym: dolichyl-phosphate-mannose--protein mannosyltransferase inhibitors
has_related_synonym: protein O-D-mannosyltransferase inhibitor
has_related_synonym: protein O-D-mannosyltransferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

Furafylline
type: Class
subclass of: molecular entity
charge: 0
monoisotopicmass: 260.09094
mass: 260.253
has_exact_synonym: 3-(uran-2-ylmethyl)-1,8-dimethyl-7H-purine-2,6-dione
formula: C12H12N4O3
database_cross_reference: CAS:80288-49-9
id: CHEBI:165840
database_cross_reference: Chemspider:3315
inchi: InChI=1S/C12H12N4O3/c1-7-13-9-10(14-7)16(6-8-4-3-5-19-8)12(18)15(2)11(9)17/h3-5H,6H2,1-2H3,(H,13,14)
inchikey: KGQZGCIVHYLPBH-UHFFFAOYSA-N
smiles: O1C(CN2C=3N=C(NC3C(=O)N(C2=O)C)C)=CC=C1
has_obo_namespace: chebi_ontology
in_subset: 2 STAR
imported from: chebi.owl

carbohydrate
type: Class
subclass of: BAO_0003111
definition: Any member of the class of organooxygen compounds that is a polyhydroxy-aldehyde or -ketone or a lactol resulting from their intramolecular condensation (monosaccharides); substances derived from these by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom; and polymeric products arising by intermolecular acetal formation between two or more such molecules (disaccharides, polysaccharides and oligosaccharides). Carbohydrates contain only carbon, hydrogen and oxygen atoms; prior to any oxidation or reduction, most have the empirical formula Cm(H2O)n. Compounds obtained from carbohydrates by substitution, etc., are known as carbohydrate derivatives and may contain other elements. Cyclitols are generally not regarded as carbohydrates.
has_alternative_id: CHEBI:15131
id: CHEBI:16646
has_alternative_id: CHEBI:23008
has_alternative_id: CHEBI:9318
has_related_synonym: Kohlenhydrat
has_related_synonym: Kohlenhydrate
database_cross_reference: Wikipedia:Carbohydrate
has_related_synonym: a carbohydrate
has_related_synonym: carbohidrato
has_related_synonym: carbohidratos
has_exact_synonym: carbohydrate
has_exact_synonym: carbohydrates
has_obo_namespace: chebi_ontology
has_related_synonym: glucide
has_related_synonym: glucides
has_related_synonym: glucido
has_related_synonym: glucidos
has_related_synonym: hydrates de carbone
has_related_synonym: saccharide
has_related_synonym: saccharides
has_related_synonym: saccharidum
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.23.15 (renin) inhibitor
type: Class
subclass of: EC 3.4.23.* (aspartic endopeptidase) inhibitor
definition: An EC 3.4.23.* (aspartic endopeptidase) inhibitor that interferes with the activity of renin (EC 3.4.23.15).
id: CHEBI:166822
has_related_synonym: EC 3.4.23.15 (renin) inhibitors
has_related_synonym: EC 3.4.23.15 inhibitor
has_related_synonym: EC 3.4.23.15 inhibitors
database_cross_reference: Wikipedia:Renin
has_related_synonym: angiotensin-forming enzyme inhibitor
has_related_synonym: angiotensin-forming enzyme inhibitors
has_related_synonym: angiotensinogenase inhibitor
has_related_synonym: angiotensinogenase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: renin inhibitor
has_related_synonym: renin inhibitors
in_subset: 3 STAR
imported from: chebi.owl

copper chelator
type: Class
subclass of: chelator
definition: A chelator that is any compound containing a ligand (typically organic) which is able to form a bond to a central copper atom at two or more points.
id: CHEBI:166831
database_cross_reference: PMID:24934357
database_cross_reference: PMID:29710396
has_obo_namespace: chebi_ontology
has_related_synonym: copper chelate
has_related_synonym: copper chelating agent
has_related_synonym: copper chelating agents
has_exact_synonym: copper chelator
has_related_synonym: copper chelators
in_subset: 3 STAR
imported from: chebi.owl

neuropilin receptor antagonist
type: Class
subclass of: antagonist
definition: An antagonist that binds to and deactivates neuropilin receptors.
id: CHEBI:166909
has_related_synonym: NRP antagonist
has_related_synonym: NRP antagonists
database_cross_reference: Wikipedia:Neuropilin
has_obo_namespace: chebi_ontology
has_related_synonym: neuropilin receptor antagonists
in_subset: 3 STAR
imported from: chebi.owl

kappa-opioid receptor antagonist
type: Class
subclass of: kappa-opioid agent
subclass of: opioid receptor antagonist
definition: Any compound that exhibits antagonist activity at the kappa-opioid receptor.
id: CHEBI:167165
has_obo_namespace: chebi_ontology
has_related_synonym: kappa-opioid antagonist
has_related_synonym: kappa-opioid antagonists
has_related_synonym: kappa-opioid receptor antagonists
in_subset: 3 STAR
imported from: chebi.owl

piscicide
type: Class
subclass of: pesticide
definition: A substance which is poisonous to fish and is primarily used to eliminate dominant species of fish in water.
id: CHEBI:167183
database_cross_reference: Wikipedia:Piscicide
has_obo_namespace: chebi_ontology
has_related_synonym: piscicides
in_subset: 3 STAR
imported from: chebi.owl

ovicide
type: Class
subclass of: insecticide
definition: Any insecticide that is capable of killing egg cells.
id: CHEBI:167523
has_obo_namespace: chebi_ontology
has_related_synonym: ovicides
in_subset: 3 STAR
imported from: chebi.owl

CPSF3 inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
definition: Any inhibitor which inhibits the activity of cleavage and polyadenylation specificity factor subunit 3 protein (CPSF3).
id: CHEBI:167633
has_related_synonym: CPSF-73 inhibitor
has_related_synonym: CPSF-73 inhibitors
has_related_synonym: CPSF3 inhibitors
has_related_synonym: CPSF73 inhibitor
has_related_synonym: CPSF73 inhibitors
database_cross_reference: Wikipedia:CPSF3
has_obo_namespace: chebi_ontology
has_related_synonym: cleavage and polyadenylation specific factor 3 inhibitor
has_related_synonym: cleavage and polyadenylation specific factor 3 inhibitors
has_related_synonym: cleavage and polyadenylation specificity factor 73 KDa subunit inhibitor
has_related_synonym: cleavage and polyadenylation specificity factor 73 KDa subunit inhibitors
has_related_synonym: cleavage and polyadenylation specificity factor subunit 3 inhibitor
has_related_synonym: cleavage and polyadenylation specificity factor subunit 3 inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 6.1.1.6 (lysine--tRNA ligase) inhibitor
type: Class
subclass of: EC 6.1.1.* (ligases forming aminoacyl tRNA and related compounds) inhibitor
definition: An EC 6.1.1.* (ligases forming aminoacyl tRNA and related compounds) inhibitor that specifically inhibits the action of lysine-tRNA ligase (EC 6.1.1.6).
id: CHEBI:167677
has_related_synonym: EC 6.1.1.6 (lysine--tRNA ligase) inhibitors
has_related_synonym: EC 6.1.1.6 inhibitor
has_related_synonym: EC 6.1.1.6 inhibitors
has_related_synonym: L-lysine-transfer RNA ligase inhibitor
has_related_synonym: L-lysine-transfer RNA ligase inhibitors
has_related_synonym: L-lysine:tRNA(Lys) ligase (AMP-forming) inhibitor
has_related_synonym: L-lysine:tRNA(Lys) ligase (AMP-forming) inhibitors
has_related_synonym: LysRS inhibitor
has_related_synonym: LysRS inhibitors
database_cross_reference: Wikipedia:Lysine-tRNA_ligase
has_obo_namespace: chebi_ontology
has_related_synonym: lysine translase inhibitor
has_related_synonym: lysine translase inhibitors
has_related_synonym: lysine--tRNA ligase inhibitor
has_related_synonym: lysine--tRNA ligase inhibitors
has_related_synonym: lysine-tRNA synthetase inhibitor
has_related_synonym: lysine-tRNA synthetase inhibitors
has_related_synonym: lysyl-tRNA synthetase inhibitor
has_related_synonym: lysyl-tRNA synthetase inhibitors
has_related_synonym: lysyl-transfer RNA synthetase inhibitor
has_related_synonym: lysyl-transfer RNA synthetase inhibitors
has_related_synonym: lysyl-transfer ribonucleate synthetase inhibitor
has_related_synonym: lysyl-transfer ribonucleate synthetase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.1.1.43 (enhancer of zeste homolog 2) inhibitor
type: Class
subclass of: EC 2.1.1.* (methyltransferases) inhibitor
definition: An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of Enhancer of zeste homolog 2 (EZH2), a histone-lysine N-methyltransferase (EC 2.1.1.43).
id: CHEBI:167694
has_related_synonym: EC 2.1.1.43 (enhancer of zeste homolog 2) inhibitors
has_related_synonym: EZH2 inhibitor
has_related_synonym: EZH2 inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

necroptosis inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
definition: Any substance that inhibits the process of necroptosis (programmed form of necrosis) in organisms.
id: CHEBI:167704
has_obo_namespace: chebi_ontology
has_related_synonym: necroptosis inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor
type: Class
subclass of: DNA polymerase inhibitor
has_related_synonym: 3D polymerase inhibitor
has_related_synonym: 3D polymerase inhibitors
definition: A DNA polymerase inhibitor that interferes with the action of a RNA-directed RNA polymerase (EC 2.7.7.48).
id: CHEBI:170010
has_related_synonym: EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitors
has_related_synonym: EC 2.7.7.48 inhibitor
has_related_synonym: EC 2.7.7.48 inhibitors
has_related_synonym: PB1 proteins inhibitor
has_related_synonym: PB1 proteins inhibitors
has_related_synonym: PB2 proteins inhibitor
has_related_synonym: PB2 proteins inhibitors
has_related_synonym: Q-beta replicase inhibitor
has_related_synonym: Q-beta replicase inhibitors
has_related_synonym: RDRP inhibitor
has_related_synonym: RDRP inhibitors
has_related_synonym: RNA nucleotidyltransferase (RNA-directed) inhibitor
has_related_synonym: RNA nucleotidyltransferase (RNA-directed) inhibitors
has_related_synonym: RNA replicase inhibitor
has_related_synonym: RNA replicase inhibitors
has_related_synonym: RNA synthetase inhibitor
has_related_synonym: RNA synthetase inhibitors
has_related_synonym: RNA transcriptase inhibitor
has_related_synonym: RNA transcriptase inhibitors
has_related_synonym: RNA-dependent RNA polymerase inhibitor
has_related_synonym: RNA-dependent RNA polymerase inhibitors
has_related_synonym: RNA-dependent RNA replicase inhibitor
has_related_synonym: RNA-dependent RNA replicase inhibitors
has_related_synonym: RNA-dependent ribonucleate nucleotidyltransferase inhibitor
has_related_synonym: RNA-dependent ribonucleate nucleotidyltransferase inhibitors
has_related_synonym: RNA-directed RNA polymerase inhibitor
has_related_synonym: RNA-directed RNA polymerase inhibitors
database_cross_reference: Wikipedia:RNA-dependent_RNA_polymerase
has_obo_namespace: chebi_ontology
has_related_synonym: phage f2 replicase inhibitor
has_related_synonym: phage f2 replicase inhibitors
has_related_synonym: polymerase L inhibitor
has_related_synonym: polymerase L inhibitors
has_related_synonym: ribonucleic acid replicas inhibitor
has_related_synonym: ribonucleic acid replicas inhibitors
has_related_synonym: ribonucleic acid-dependent ribonucleate nucleotidyltransferase inhibitor
has_related_synonym: ribonucleic acid-dependent ribonucleate nucleotidyltransferase inhibitors
has_related_synonym: ribonucleic acid-dependent ribonucleic acid polymeras inhibitor
has_related_synonym: ribonucleic acid-dependent ribonucleic acid polymeras inhibitors
has_related_synonym: ribonucleic replicase inhibitor
has_related_synonym: ribonucleic replicase inhibitors
has_related_synonym: ribonucleic synthetase inhibitor
has_related_synonym: ribonucleic synthetase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

antiamoebic agent
type: Class
subclass of: antiparasitic agent
definition: An antiparasitic agent which is effective against amoeba, a genus of single-celled amoeboids in the family Amoebidae.
id: CHEBI:171664
has_related_synonym: amebicide
has_related_synonym: amebicides
has_related_synonym: amoebicide
has_related_synonym: amoebicides
has_related_synonym: anti-amoebic agent
has_related_synonym: anti-amoebic agents
has_related_synonym: anti-amoebic drug
has_related_synonym: anti-amoebic drugs
has_related_synonym: antiamoebic
has_related_synonym: antiamoebic agents
has_related_synonym: antiamoebic drug
has_related_synonym: antiamoebic drugs
has_related_synonym: antiamoebics
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 2.1.1.348 (mRNA m6A methyltransferase) inhibitor
type: Class
subclass of: EC 2.1.1.* (methyltransferases) inhibitor
definition: An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of mRNA m6A methyltransferase (EC 2.1.1.348).
id: CHEBI:172326
has_related_synonym: EC 2.1.1.348 (mRNA m6A methyltransferase) inhibitors
has_related_synonym: EC 2.1.1.348 inhibitor
has_related_synonym: EC 2.1.1.348 inhibitors
has_related_synonym: METTL14 inhibitor
has_related_synonym: METTL14 inhibitors
has_related_synonym: METTL3 inhibitor
has_related_synonym: METTL3 inhibitors
database_cross_reference: Wikipedia:METTL3
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 2.6.1.11 (acetylornithine transaminase) inhibitor
type: Class
subclass of: EC 2.6.1.* (transaminase) inhibitor
has_related_synonym: 2-N-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase inhibitor
has_related_synonym: 2-N-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase inhibitors
has_related_synonym: ACOAT inhibitor
has_related_synonym: ACOAT inhibitors
definition: An EC 2.6.1.* (transaminase) inhibitor that interferes with the action of acetylornithine transaminase (EC 2.6.1.11).
id: CHEBI:172919
has_related_synonym: EC 2.6.1.11 (acetylornithine transaminase) inhibitors
has_related_synonym: EC 2.6.1.11 inhibitor
has_related_synonym: EC 2.6.1.11 inhibitors
has_related_synonym: N(2)-acetyl-L-ornithine:2-oxoglutarate aminotransferase inhibitor
has_related_synonym: N(2)-acetyl-L-ornithine:2-oxoglutarate aminotransferase inhibitors
has_related_synonym: N(2)-acetylornithine 5-transaminase inhibitor
has_related_synonym: N(2)-acetylornithine 5-transaminase inhibitors
has_related_synonym: N-acetylornithine aminotransferase inhibitor
has_related_synonym: N-acetylornithine aminotransferase inhibitors
has_related_synonym: N-acetylornithine-delta-transaminase inhibitor
has_related_synonym: N-acetylornithine-delta-transaminase inhibitors
database_cross_reference: Wikipedia:Acetylornithine_transaminase
has_related_synonym: acetylornithine 5-aminotransferase inhibitor
has_related_synonym: acetylornithine 5-aminotransferase inhibitors
has_related_synonym: acetylornithine aminotransferase inhibitor
has_related_synonym: acetylornithine aminotransferase inhibitors
has_related_synonym: acetylornithine delta-transaminase inhibitor
has_related_synonym: acetylornithine delta-transaminase inhibitors
has_related_synonym: acetylornithine transaminase inhibitor
has_related_synonym: acetylornithine transaminase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: succinylornithine aminotransferase inhibitor
has_related_synonym: succinylornithine aminotransferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

antimicrobial cosmetic preservative
type: Class
subclass of: antimicrobial agent
definition: An antimicrobial agent that is added to cosmetic formulations to maintain the microbiological safety of the products by inhibiting the growth of fungi or bacteria.
id: CHEBI:172949
has_related_synonym: antimicrobial cosmetic preservatives
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

ferroptosis inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
definition: Any substance that inhibits the process of ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms.
id: CHEBI:173084
database_cross_reference: PMID:32015325
database_cross_reference: PMID:32256352
database_cross_reference: PMID:32413317
database_cross_reference: PMID:33495651
database_cross_reference: Wikipedia:Ferroptosis
has_obo_namespace: chebi_ontology
has_related_synonym: ferroptosis inhibitors
in_subset: 3 STAR
imported from: chebi.owl

ferroptosis inducer
type: Class
subclass of: biochemical role
definition: Any substance that induces or promotes ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms.
id: CHEBI:173085
database_cross_reference: PMID:31899616
database_cross_reference: PMID:32015325
database_cross_reference: PMID:33167414
database_cross_reference: PMID:34012798
database_cross_reference: Wikipedia:Ferroptosis
has_obo_namespace: chebi_ontology
has_related_synonym: ferroptosis inducers
in_subset: 3 STAR
imported from: chebi.owl

EC 3.1.3.25 (inositol-phosphate phosphatase) inhibitor
type: Class
subclass of: EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor
definition: An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of inositol-phosphate phosphatase (EC 3.1.3.25).
id: CHEBI:173094
has_related_synonym: EC 3.1.3.25 (inositol-phosphate phosphatase) inhibitors
has_related_synonym: EC 3.1.3.25 inhibitor
has_related_synonym: EC 3.1.3.25 inhibitors
has_related_synonym: IMPase inhibitor
has_related_synonym: IMPase inhibitors
has_related_synonym: L-myo-inositol-1-phosphate phosphatase inhibitor
has_related_synonym: L-myo-inositol-1-phosphate phosphatase inhibitors
database_cross_reference: Wikipedia:Inositol-phosphate_phosphatase
has_obo_namespace: chebi_ontology
has_related_synonym: inositol 1-phosphatase inhibitor
has_related_synonym: inositol 1-phosphatase inhibitors
has_related_synonym: inositol monophosphatase inhibitor
has_related_synonym: inositol monophosphatase inhibitors
has_related_synonym: inositol monophosphate phosphatase inhibitor
has_related_synonym: inositol monophosphate phosphatase inhibitors
has_related_synonym: inositol phosphatase inhibitor
has_related_synonym: inositol phosphatase inhibitors
has_related_synonym: inositol phosphate phosphatase inhibitor
has_related_synonym: inositol phosphate phosphatase inhibitors
has_related_synonym: inositol-1(or 4)-monophosphatase inhibitor
has_related_synonym: inositol-1(or 4)-monophosphatase inhibitors
has_related_synonym: inositol-phosphate phosphatase inhibitor
has_related_synonym: inositol-phosphate phosphatase inhibitors
has_related_synonym: myo-inositol 1-phosphatase inhibitor
has_related_synonym: myo-inositol 1-phosphatase inhibitors
has_related_synonym: myo-inositol monophosphatase inhibitor
has_related_synonym: myo-inositol monophosphatase inhibitors
has_related_synonym: myo-inositol-1(or 4)-monophosphatase inhibitor
has_related_synonym: myo-inositol-1(or 4)-monophosphatase inhibitors
has_related_synonym: myo-inositol-1(or 4)-phosphate phosphohydrolase inhibitor
has_related_synonym: myo-inositol-1(or 4)-phosphate phosphohydrolase inhibitors
has_related_synonym: myo-inositol-1-phosphatase inhibitor
has_related_synonym: myo-inositol-1-phosphatase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

voltage-dependent anion channel inhibitor
type: Class
subclass of: ion transport inhibitor
definition: Any agent that inhibits voltage-dependent anion channels.
id: CHEBI:173100
has_related_synonym: VDAC blocker
has_related_synonym: VDAC blockers
has_related_synonym: VDAC inhibitor
has_related_synonym: VDAC inhibitors
database_cross_reference: Wikipedia:Voltage-dependent_anion_channel
has_obo_namespace: chebi_ontology
has_related_synonym: voltage-dependent anion channel blocker
has_related_synonym: voltage-dependent anion channel blockers
has_related_synonym: voltage-dependent anion channel inhibitors
has_related_synonym: voltage-dependent anion-selective channel blocker
has_related_synonym: voltage-dependent anion-selective channel blockers
has_related_synonym: voltage-dependent anion-selective channel inhibitor
has_related_synonym: voltage-dependent anion-selective channel inhibitors
in_subset: 3 STAR
imported from: chebi.owl

thioredoxin inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
definition: Any substance which inhibits thioredoxin, a group of small redox proteins.
id: CHEBI:173108
has_related_synonym: TRX inhibitor
has_related_synonym: TRX inhibitors
has_related_synonym: TRX1 inhibitor
has_related_synonym: TRX1 inhibitors
has_related_synonym: TXN inhibitor
has_related_synonym: TXN inhibitors
database_cross_reference: Wikipedia:Thioredoxin
has_obo_namespace: chebi_ontology
has_related_synonym: thioredoxin inhibitors
in_subset: 3 STAR
imported from: chebi.owl

testosterone
type: Class
subclass of: molecular entity
charge: 0
has_related_synonym: 17beta-Hydroxy-4-androsten-3-one
has_related_synonym: 17beta-hydroxy-4-androsten-3-one
has_exact_synonym: 17beta-hydroxyandrost-4-en-3-one
monoisotopicmass: 288.20893
mass: 288.42440
has_related_synonym: 4-androsten-17beta-ol-3-one
definition: An androstanoid having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5..
has_related_synonym: Androderm
database_cross_reference: Beilstein:3653705
formula: C19H28O2
database_cross_reference: CAS:58-22-0
has_alternative_id: CHEBI:15214
id: CHEBI:17347
has_alternative_id: CHEBI:26883
has_alternative_id: CHEBI:45798
has_alternative_id: CHEBI:9461
database_cross_reference: DrugBank:DB00624
database_cross_reference: Drug_Central:2607
database_cross_reference: Gmelin:538843
database_cross_reference: HMDB:HMDB0000234
inchi: InChI=1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-17,21H,3-10H2,1-2H3/t14-,15-,16-,17-,18-,19-/m0/s1
database_cross_reference: KEGG:C00535
database_cross_reference: KEGG:D00075
database_cross_reference: KNApSAcK:C00003675
database_cross_reference: LIPID_MAPS_instance:LMST02020002
inchikey: MUMGGOZAMZWBJJ-DYKIIFRCSA-N
database_cross_reference: PDBeChem:TES
database_cross_reference: PMID:10438974
database_cross_reference: PMID:11786693
database_cross_reference: PMID:18900503
database_cross_reference: PMID:24498482
database_cross_reference: Reaxys:1915399
has_exact_synonym: TESTOSTERONE
has_related_synonym: Testosteron
has_exact_synonym: Testosterone
database_cross_reference: Wikipedia:Testosterone
has_obo_namespace: chebi_ontology
has_related_synonym: testosterona
has_exact_synonym: testosterone
has_related_synonym: testosterone
has_related_synonym: testosteronum
in_subset: 3 STAR
imported from: chebi.owl

EC 1.11.1.9 (glutathione peroxidase) inhibitor
type: Class
subclass of: EC 1.11.1.* (peroxidases) inhibitor
definition: An inhibitor of peroxidases (EC 1.11.1.*) that inhibits the action of glutathione peroxidase (EC 1.11.1.9).
id: CHEBI:176342
has_related_synonym: EC 1.11.1.9 (glutathione peroxidase) inhibitors
has_related_synonym: EC 1.11.1.9 inhibitor
has_related_synonym: EC 1.11.1.9 inhibitors
has_related_synonym: GSH peroxidase inhibitor
has_related_synonym: GSH peroxidase inhibitors
database_cross_reference: Wikipedia:Glutathione_peroxidase
has_obo_namespace: chebi_ontology
has_related_synonym: glutathione peroxidase inhibitor
has_related_synonym: glutathione peroxidase inhibitors
has_related_synonym: reduced glutathione peroxidase inhibitor
has_related_synonym: reduced glutathione peroxidase inhibitors
has_related_synonym: selenium-glutathione peroxidase inhibitor
has_related_synonym: selenium-glutathione peroxidase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

actin polymerisation inducer
type: Class
subclass of: biochemical role
definition: Any substance that induces the polymerisation of the protein actin.
id: CHEBI:176495
database_cross_reference: PMID:33066873
has_related_synonym: actin polymerisation enhancer
has_related_synonym: actin polymerisation enhancers
has_related_synonym: actin polymerisation inducers
has_obo_namespace: chebi_ontology
has_related_synonym: inducer of actin polymerization
has_related_synonym: inducers of actin polymerization
in_subset: 3 STAR
imported from: chebi.owl

geroprotector
type: Class
subclass of: protective agent
definition: Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.
id: CHEBI:176497
database_cross_reference: PMID:23372317
database_cross_reference: PMID:28580190
database_cross_reference: PMID:30885572
database_cross_reference: PMID:33144142
database_cross_reference: PMID:33973253
database_cross_reference: PMID:34606237
database_cross_reference: Wikipedia:Geroprotector
has_related_synonym: anti-aging agent
has_related_synonym: anti-aging agents
has_related_synonym: anti-aging drug
has_related_synonym: anti-aging drugs
has_obo_namespace: chebi_ontology
has_related_synonym: geroprotective agent
has_related_synonym: geroprotective agents
has_related_synonym: geroprotectors
in_subset: 3 STAR
imported from: chebi.owl

ferroptosis suppressor protein 1 inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
has_related_synonym: AIFM2 inhibitor
has_related_synonym: AIFM2 inhibitors
definition: An inhibitor which inhibits the action of ferroptosis suppressor protein 1.
id: CHEBI:176508
has_related_synonym: FSP1 inhibitor
has_related_synonym: FSP1 inhibitors
database_cross_reference: Wikipedia:AIFM2
has_related_synonym: apoptosis-inducing factor mitochondria-associated 2 inhibitor
has_related_synonym: apoptosis-inducing factor mitochondria-associated 2 inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: ferroptosis suppressor protein 1 inhibitors
in_subset: 3 STAR
imported from: chebi.owl

electron acceptor
type: Class
subclass of: acceptor
definition: A substance to which an electron may be transferred.
has_alternative_id: CHEBI:14207
has_alternative_id: CHEBI:14716
id: CHEBI:17654
has_alternative_id: CHEBI:7835
has_related_synonym: Elektronenakzeptor
database_cross_reference: KEGG:C02177
has_related_synonym: Oxidized donor
has_obo_namespace: chebi_ontology
has_exact_synonym: electron acceptor
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.11.2 - [pyruvate dehydrogenase (acetyl-transferring)] kinase inhibitor
type: Class
subclass of: EC 2.7.11.* (protein-serine/threonine kinase) inhibitor
definition: An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of pyruvate dehydrogenase (acetyl-transferring) kinase (EC 2.7.11.2).
id: CHEBI:176961
has_related_synonym: EC 2.7.11.2 - [pyruvate dehydrogenase (acetyl-transferring)] kinase inhibitors
has_related_synonym: EC 2.7.11.2 inhibitor
has_related_synonym: EC 2.7.11.2 inhibitors
has_related_synonym: PDH kinase inhibitor
has_related_synonym: PDH kinase inhibitors
has_related_synonym: PDHK inhibitor
has_related_synonym: PDHK inhibitors
has_related_synonym: PDK inhibitor
has_related_synonym: PDK inhibitors
has_related_synonym: PDK1 inhibitor
has_related_synonym: PDK1 inhibitors
has_related_synonym: PDK2 inhibitor
has_related_synonym: PDK2 inhibitors
has_related_synonym: PDK3 inhibitor
has_related_synonym: PDK3 inhibitors
has_related_synonym: PDK4 inhibitor
has_related_synonym: PDK4 inhibitors
has_related_synonym: STK1 inhibitor
has_related_synonym: STK1 inhibitors
database_cross_reference: Wikipedia:Pyruvate_dehydrogenase_kinase
has_related_synonym: [pyruvate dehydrogenase (acetyl-transferring)] kinase inhibitor
has_related_synonym: [pyruvate dehydrogenase (acetyl-transferring)] kinase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: pyruvate dehydrogenase (acetyl-transferring) kinase inhibitor
has_related_synonym: pyruvate dehydrogenase (acetyl-transferring) kinase inhibitors
has_related_synonym: pyruvate dehydrogenase kinase (phosphorylating) inhibitor
has_related_synonym: pyruvate dehydrogenase kinase (phosphorylating) inhibitors
has_related_synonym: pyruvate dehydrogenase kinase activator protein inhibitor
has_related_synonym: pyruvate dehydrogenase kinase activator protein inhibitors
has_related_synonym: pyruvate dehydrogenase kinase inhibitor
has_related_synonym: pyruvate dehydrogenase kinase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

somatostatin receptor agonist
type: Class
subclass of: G-protein-coupled receptor agonist
definition: An agonist that binds to and activates somatostatin receptors.
id: CHEBI:177023
has_related_synonym: SRIF agonist
has_related_synonym: SRIF agonists
has_related_synonym: SS-R agonist
has_related_synonym: SS-R agonists
has_related_synonym: SSR agonist
has_related_synonym: SSR agonists
has_related_synonym: SSTR agonist
has_related_synonym: SSTR agonists
database_cross_reference: Wikipedia:Somatostatin_receptor
has_obo_namespace: chebi_ontology
has_related_synonym: somatostatin receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

donor
type: Class
subclass of: chemical role
definition: A molecular entity that can transfer ("donate") an electron, a pair of electrons, an atom or a group to another molecular entity.
has_alternative_id: CHEBI:14202
id: CHEBI:17891
has_alternative_id: CHEBI:4697
has_related_synonym: Donator
has_exact_synonym: Donor
database_cross_reference: KEGG:C01351
has_obo_namespace: chebi_ontology
has_related_synonym: donneur
in_subset: 3 STAR
imported from: chebi.owl

(S)-Mephenytoin
type: Class
subclass of: molecular entity
has_exact_synonym: (5S)-5-ethyl-3-methyl-5-phenylimidazolidine-2,4-dione
charge: 0
monoisotopicmass: 218.10553
mass: 218.256
formula: C12H14N2O2
database_cross_reference: CAS:70989-04-7
id: CHEBI:179062
database_cross_reference: Chemspider:97046
inchikey: GMHKMTDVRCWUDX-LBPRGKRZSA-N
inchi: InChI=1S/C12H14N2O2/c1-3-12(9-7-5-4-6-8-9)10(15)14(2)11(16)13-12/h4-8H,3H2,1-2H3,(H,13,16)/t12-/m0/s1
database_cross_reference: KEGG:C20130
smiles: O=C1N(C(=O)N[C@@]1(CC)C2=CC=CC=C2)C
has_obo_namespace: chebi_ontology
in_subset: 2 STAR
imported from: chebi.owl

neoantigen
type: Class
subclass of: antigen
definition: A mainly tumour-specific antigen generated by mutations in tumour cells. Neoantigens are only expressed in tumour cells.
id: CHEBI:183050
has_obo_namespace: chebi_ontology
has_related_synonym: neoantigens
in_subset: 3 STAR
imported from: chebi.owl

EC 3.2.1.52 (beta-N-acetylhexosaminidase) inhibitor
type: Class
subclass of: EC 3.2.1.* (glycosidase) inhibitor
definition: An EC 3.2.1.* (glycosidase) inhibitor that interferes with the action of beta-N-acetylhexosaminidase (EC 3.2.1.52).
id: CHEBI:184301
has_related_synonym: EC 3.2.1.52 (beta-N-acetylhexosaminidase) inhibitors
has_related_synonym: EC 3.2.1.52 inhibitor
has_related_synonym: EC 3.2.1.52 inhibitors
has_related_synonym: N-acetyl-beta-D-hexosaminidase inhibitor
has_related_synonym: N-acetyl-beta-D-hexosaminidase inhibitors
has_related_synonym: N-acetyl-beta-hexosaminidase inhibitor
has_related_synonym: N-acetyl-beta-hexosaminidase inhibitors
has_related_synonym: N-acetylhexosaminidase inhibitor
has_related_synonym: N-acetylhexosaminidase inhibitors
database_cross_reference: Wikipedia:Hexosaminidase
has_related_synonym: beta-D-N-acetylhexosaminidase inhibitor
has_related_synonym: beta-D-N-acetylhexosaminidase inhibitors
has_related_synonym: beta-D-hexosaminidase inhibitor
has_related_synonym: beta-D-hexosaminidase inhibitors
has_related_synonym: beta-N-acetyl-D-hexosaminidase inhibitor
has_related_synonym: beta-N-acetyl-D-hexosaminidase inhibitors
has_related_synonym: beta-N-acetylglucosaminidase inhibitor
has_related_synonym: beta-N-acetylglucosaminidase inhibitors
has_related_synonym: beta-N-acetylhexosaminidase inhibitor
has_related_synonym: beta-N-acetylhexosaminidase inhibitors
has_related_synonym: beta-acetylaminodeoxyhexosidase inhibitor
has_related_synonym: beta-acetylaminodeoxyhexosidase inhibitors
has_related_synonym: beta-acetylhexosaminidinase inhibitor
has_related_synonym: beta-acetylhexosaminidinase inhibitors
has_related_synonym: beta-hexosaminidase inhibitor
has_related_synonym: beta-hexosaminidase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: hexosaminidase A inhibitor
has_related_synonym: hexosaminidase A inhibitors
has_related_synonym: hexosaminidase inhibitor
has_related_synonym: hexosaminidase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.14.14.91 ( trans-cinnamate 4-monooxygenase) inhibitor
type: Class
subclass of: EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor
definition: Any EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor that interferes with the action of trans-cinnamate 4-monooxygenase (EC 1.14.14.91).
has_related_synonym: CA4H inhibitor
has_related_synonym: CA4H inhibitors
id: CHEBI:184380
has_related_synonym: EC 1.14.14.91 ( trans-cinnamate 4-monooxygenase) inhibitors
has_related_synonym: EC 1.14.14.91 inhibitor
has_related_synonym: EC 1.14.14.91 inhibitors
database_cross_reference: Wikipedia:Trans-cinnamate_4-monooxygenase
has_obo_namespace: chebi_ontology
has_related_synonym: cinnamate 4-hydroxylase inhibitor
has_related_synonym: cinnamate 4-hydroxylase inhibitors
has_related_synonym: cinnamate 4-monooxygenase inhibitor
has_related_synonym: cinnamate 4-monooxygenase inhibitors
has_related_synonym: cinnamate hydroxylase inhibitor
has_related_synonym: cinnamate hydroxylase inhibitors
has_related_synonym: cinnamic 4-hydroxylase inhibitor
has_related_synonym: cinnamic 4-hydroxylase inhibitors
has_related_synonym: cinnamic acid 4-hydroxylase inhibitor
has_related_synonym: cinnamic acid 4-hydroxylase inhibitors
has_related_synonym: cinnamic acid 4-monooxygenase inhibitor
has_related_synonym: cinnamic acid 4-monooxygenase inhibitors
has_related_synonym: cinnamic acid p-hydroxylase inhibitor
has_related_synonym: cinnamic acid p-hydroxylase inhibitors
has_related_synonym: cytochrome P450 cinnamate 4-hydroxylase inhibitor
has_related_synonym: cytochrome P450 cinnamate 4-hydroxylase inhibitors
has_related_synonym: t-cinnamic acid hydroxylase inhibitor
has_related_synonym: t-cinnamic acid hydroxylase inhibitors
has_related_synonym: trans-cinnamate 4-hydroxylase inhibitor
has_related_synonym: trans-cinnamate 4-hydroxylase inhibitors
has_related_synonym: trans-cinnamate 4-monooxygenase inhibitor
has_related_synonym: trans-cinnamate 4-monooxygenase inhibitors
has_related_synonym: trans-cinnamic acid 4-hydroxylase inhibitor
has_related_synonym: trans-cinnamic acid 4-hydroxylase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

urea herbicide
type: Class
subclass of: herbicide
definition: Any herbicide composed of urea or substituted urea substructure.
id: CHEBI:188147
has_obo_namespace: chebi_ontology
has_related_synonym: substituted urea herbicide
has_related_synonym: substituted urea herbicides
has_related_synonym: urea herbicides
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.21.61 (kexin) inhibitor
type: Class
subclass of: EC 3.4.21.* (serine endopeptidase) inhibitor
definition: An EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of kexin (EC 3.4.21.61).
id: CHEBI:189665
has_related_synonym: EC 3.4.21.61 (kexin) inhibitors
has_related_synonym: EC 3.4.21.61 inhibitor
has_related_synonym: EC 3.4.21.61 inhibitors
has_related_synonym: Kex 2p proteinase inhibitor
has_related_synonym: Kex 2p proteinase inhibitors
has_related_synonym: Kex2 endopeptidase inhibitor
has_related_synonym: Kex2 endopeptidase inhibitors
has_related_synonym: Kex2 endoprotease inhibitor
has_related_synonym: Kex2 endoprotease inhibitors
has_related_synonym: Kex2 endoproteinase inhibitor
has_related_synonym: Kex2 endoproteinase inhibitors
has_related_synonym: Kex2 protease inhibitor
has_related_synonym: Kex2 protease inhibitors
has_related_synonym: Kex2 proteinase inhibitor
has_related_synonym: Kex2 proteinase inhibitors
has_related_synonym: Kex2-like endoproteinase inhibitor
has_related_synonym: Kex2-like endoproteinase inhibitors
has_related_synonym: Kex2-like precursor protein processing endoprotease inhibitor
has_related_synonym: Kex2-like precursor protein processing endoprotease inhibitors
has_related_synonym: andrenorphin-Gly-generating enzyme inhibitor
has_related_synonym: andrenorphin-Gly-generating enzyme inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: endoproteinase Kex2p inhibitor
has_related_synonym: endoproteinase Kex2p inhibitors
has_related_synonym: gene KEX2 dibasic proteinase inhibitor
has_related_synonym: gene KEX2 dibasic proteinase inhibitors
has_related_synonym: kexin inhibitor
has_related_synonym: kexin inhibitors
has_related_synonym: paired-basic endopeptidase inhibitor
has_related_synonym: paired-basic endopeptidase inhibitors
has_related_synonym: prohormone-processing KEX2 proteinase inhibitor
has_related_synonym: prohormone-processing KEX2 proteinase inhibitors
has_related_synonym: prohormone-processing endoprotease inhibitor
has_related_synonym: prohormone-processing endoprotease inhibitors
has_related_synonym: prohormone-processing proteinase inhibitor
has_related_synonym: prohormone-processing proteinase inhibitors
has_related_synonym: proprotein convertase inhibitor
has_related_synonym: proprotein convertase inhibitors
has_related_synonym: protease KEX2 inhibitor
has_related_synonym: protease KEX2 inhibitors
has_related_synonym: proteinase Kex2p inhibitor
has_related_synonym: proteinase Kex2p inhibitors
has_related_synonym: proteinase yscF inhibitor
has_related_synonym: proteinase yscF inhibitors
has_related_synonym: yeast KEX2 protease inhibitor
has_related_synonym: yeast KEX2 protease inhibitors
in_subset: 3 STAR
imported from: chebi.owl

PAR2 negative allosteric modulator
type: Class
subclass of: protease-activated receptor-2 antagonist
subclass of: receptor modulator
id: CHEBI:189675
definition: a group of substances that bind to a receptor to change that receptor's response to stimulus.
has_obo_namespace: chebi_ontology
in_subset: 2 STAR
imported from: chebi.owl

protease-activated receptor-2 antagonist
type: Class
subclass of: G-protein-coupled receptor antagonist
definition: An antagonist at the protease-activated receptor-2.
id: CHEBI:189676
has_related_synonym: G-protein coupled receptor 11 antagonist
has_related_synonym: G-protein coupled receptor 11 antagonists
has_related_synonym: GPR11 antagonist
has_related_synonym: GPR11 antagonists
has_related_synonym: PAR-2 antagonist
has_related_synonym: PAR-2 antagonists
has_related_synonym: PAR2 antagonist
has_related_synonym: PAR2 antagonists
database_cross_reference: PMID:10657317
database_cross_reference: Wikipedia:Protease-activated_receptor_2
has_obo_namespace: chebi_ontology
has_related_synonym: coagulation factor II (thrombin) receptor-like 1 antagonist
has_related_synonym: coagulation factor II (thrombin) receptor-like 1 antagonists
has_related_synonym: protease-activated receptor 2 antagonist
has_related_synonym: protease-activated receptor 2 antagonists
has_related_synonym: protease-activated receptor-2 antagonists
in_subset: 3 STAR
imported from: chebi.owl

sigma receptor modulator
type: Class
subclass of: receptor modulator
definition: Any receptor modulator acting on sigma receptors.
id: CHEBI:189683
database_cross_reference: Wikipedia:Sigma_receptor
has_obo_namespace: chebi_ontology
has_related_synonym: sigma receptor modulators
has_related_synonym: sigma-receptor modulator
has_related_synonym: sigma-receptor modulators
in_subset: 3 STAR
imported from: chebi.owl

sigma-2 receptor agonist
type: Class
subclass of: sigma receptor modulator
definition: A sigma receptor modulator that activates the sigma-2 receptor.
id: CHEBI:189684
database_cross_reference: Wikipedia:Sigma-2_receptor
has_obo_namespace: chebi_ontology
has_related_synonym: sigma 2 receptor agonist
has_related_synonym: sigma 2 receptor agonists
has_related_synonym: sigma-2 receptor agonists
has_related_synonym: sigma2 receptor agonist
has_related_synonym: sigma2 receptor agonists
has_related_synonym: sigma2R agonist
has_related_synonym: sigma2R agonists
in_subset: 3 STAR
imported from: chebi.owl

ceramide mimetic
type: Class
subclass of: biological role
definition: Any compound that mimics the activity of a ceramide, e.g. by inducing tumor cell death or suppression.
id: CHEBI:190286
has_related_synonym: ceramide mimetics
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 3.2.1.24 (alpha-mannosidase) inhibitor
type: Class
subclass of: EC 3.2.1.* (glycosidase) inhibitor
has_related_synonym: 1,2-alpha-D-mannosidase inhibitor
has_related_synonym: 1,2-alpha-D-mannosidase inhibitors
has_related_synonym: 1,2-alpha-mannosidase inhibitor
has_related_synonym: 1,2-alpha-mannosidase inhibitors
definition: An EC 3.2.1.* (glycosidase) inhibitor that interferes with the action of alpha-mannosidase (EC 3.2.1.24).
id: CHEBI:191196
has_related_synonym: EC 3.2.1.24 (alpha-mannosidase) inhibitors
has_related_synonym: EC 3.2.1.24 inhibitor
has_related_synonym: EC 3.2.1.24 inhibitors
database_cross_reference: Wikipedia:Alpha-Mannosidase
has_related_synonym: alpha-D-mannopyranosidase inhibitor
has_related_synonym: alpha-D-mannopyranosidase inhibitors
has_related_synonym: alpha-D-mannosidase inhibitor
has_related_synonym: alpha-D-mannosidase inhibitors
has_related_synonym: alpha-mannosidase inhibitor
has_related_synonym: alpha-mannosidase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: exo-alpha-mannosidase inhibitor
has_related_synonym: exo-alpha-mannosidase inhibitors
has_related_synonym: p-nitrophenyl-alpha-mannosidase inhibitor
has_related_synonym: p-nitrophenyl-alpha-mannosidase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

CB1 receptor agonist
type: Class
subclass of: cannabinoid receptor agonist
definition: A cannabinoid receptor agonist that binds to and activates type 1 cannabinoid receptors.
has_exact_synonym: CB1 receptor agonist
has_related_synonym: CB1 receptor agonists
has_related_synonym: CB1R agonist
has_related_synonym: CB1R agonists
id: CHEBI:192269
database_cross_reference: Wikipedia:Cannabinoid_receptor_type_1
has_related_synonym: cannabinoid receptor 1 agonist
has_related_synonym: cannabinoid receptor 1 agonists
has_related_synonym: cannabinoid receptor type 1 agonist
has_related_synonym: cannabinoid receptor type 1 agonists
has_obo_namespace: chebi_ontology
has_related_synonym: type 1 cannabinoid receptor agonist
has_related_synonym: type 1 cannabinoid receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

elicitor
type: Class
subclass of: biochemical role
definition: A chemical or biochemical compound that is introduced in small concentrations to a living system to promote the biosynthesis of the target bioactive compound.
id: CHEBI:192504
database_cross_reference: PMID:25969762
database_cross_reference: Wikipedia:Elicitor
has_obo_namespace: chebi_ontology
has_related_synonym: elicitors
in_subset: 2 STAR
imported from: chebi.owl

EC 6.2.1.45 (E1 ubiquitin-activating enzyme) inhibitor
type: Class
subclass of: EC 6.2.1.* (acid-thiol ligase) inhibitor
definition: An EC 6.2.1.* (acid-thiol ligase) inhibitor that interferes with the action of E1 ubiquitin-activating enzyme (EC 6.2.1.45).
id: CHEBI:192999
has_related_synonym: E1 inhibitor
has_related_synonym: E1 inhibitors
has_related_synonym: E1 ubiquitin-activating enzyme inhibitor
has_related_synonym: E1 ubiquitin-activating enzyme inhibitors
has_related_synonym: EC 6.2.1.45 (E1 ubiquitin-activating enzyme) inhibitors
has_related_synonym: EC 6.2.1.45 inhibitor
has_related_synonym: EC 6.2.1.45 inhibitors
database_cross_reference: Wikipedia:Ubiquitin-activating_enzyme
has_obo_namespace: chebi_ontology
has_related_synonym: ubiquitin activating enzyme inhibitor
has_related_synonym: ubiquitin activating enzyme inhibitors
has_related_synonym: ubiquitin-activating enzyme E1 inhibitor
has_related_synonym: ubiquitin-activating enzyme E1 inhibitors
in_subset: 3 STAR
imported from: chebi.owl

neurokinin-1 receptor agonist
type: Class
subclass of: agonist
definition: An agonist at the neurokinin-1 receptor.
id: CHEBI:194137
has_related_synonym: NK-1 receptor agonist
has_related_synonym: NK-1 receptor agonists
has_related_synonym: NK1 receptor agonist
has_related_synonym: NK1 receptor agonists
has_obo_namespace: chebi_ontology
has_related_synonym: neurokinin-1 receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

protease-activated receptor-1 agonist
type: Class
subclass of: G-protein-coupled receptor agonist
definition: An agonist at the protease-activated receptor-1.
id: CHEBI:194153
has_related_synonym: PAR-1 agonist
has_related_synonym: PAR-1 agonists
has_related_synonym: PAR-1 receptor agonist
has_related_synonym: PAR-1 receptor agonists
has_related_synonym: PAR1 agonist
has_related_synonym: PAR1 agonists
database_cross_reference: PMID:11487506
database_cross_reference: PMID:12606620
database_cross_reference: PMID:29343648
database_cross_reference: Wikipedia:Coagulation_factor_II_receptor
has_obo_namespace: chebi_ontology
has_related_synonym: coagulation factor II (thrombin) receptor agonist
has_related_synonym: coagulation factor II (thrombin) receptor agonists
has_related_synonym: coagulation factor II receptor agonist
has_related_synonym: coagulation factor II receptor agonists
has_related_synonym: coagulation factor II thrombin receptor agonist
has_related_synonym: coagulation factor II thrombin receptor agonists
has_related_synonym: protease activated receptor 1 agonist
has_related_synonym: protease activated receptor 1 agonists
has_related_synonym: protease-activated receptor 1 agonist
has_related_synonym: protease-activated receptor 1 agonists
has_related_synonym: protease-activated receptor-1 agonists
has_related_synonym: proteinase-activated receptor 1 agonist
has_related_synonym: proteinase-activated receptor 1 agonists
in_subset: 3 STAR
imported from: chebi.owl

piezo1 agonist
type: Class
subclass of: agonist
definition: An agonist that binds to and activates piezo1 receptors.
id: CHEBI:194154
has_exact_synonym: PIEZO1 agonist
has_related_synonym: PIEZO1 agonists
database_cross_reference: Wikipedia:PIEZO1
has_obo_namespace: chebi_ontology
has_related_synonym: piezo type mechanosensitive ion channel component 1 agonist
has_related_synonym: piezo type mechanosensitive ion channel component 1 agonists
has_related_synonym: piezo-type mechanosensitive ion channel component 1 agonist
has_related_synonym: piezo-type mechanosensitive ion channel component 1 agonists
has_related_synonym: piezo1 agonists
in_subset: 3 STAR
imported from: chebi.owl

mitochondrial calcium uniporter inhibitor
type: Class
subclass of: inhibitor
definition: Any inhibitor of mitochondrial calcium uniporter.
id: CHEBI:194181
has_related_synonym: MCU inhibitor
has_related_synonym: MCU inhibitors
database_cross_reference: Wikipedia:Mitochondrial_calcium_uniporter
has_obo_namespace: chebi_ontology
has_related_synonym: mitochondrial calcium uniporter blocker
has_related_synonym: mitochondrial calcium uniporter blockers
has_related_synonym: mitochondrial calcium uniporter inhibitors
in_subset: 3 STAR
imported from: chebi.owl

gastric inhibitory polypeptide receptor agonist
type: Class
subclass of: G-protein-coupled receptor agonist
definition: An agonist that binds to and activates gastric inhibitory polypeptide (GIP) receptors.
id: CHEBI:194187
has_related_synonym: GIP agonist
has_related_synonym: GIP agonists
has_related_synonym: GIP receptor agonist
has_related_synonym: GIP receptor agonists
has_related_synonym: GIP-R agonist
has_related_synonym: GIP-R agonists
has_related_synonym: GIPR agonist
has_related_synonym: GIPR agonists
database_cross_reference: Wikipedia:Gastric_inhibitory_polypeptide_receptor
has_obo_namespace: chebi_ontology
has_related_synonym: gastric inhibitory polypeptide receptor agonists
has_related_synonym: glucose-dependent insulinotropic polypeptide receptor agonist
has_related_synonym: glucose-dependent insulinotropic polypeptide receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

T-type calcium channel blocker
type: Class
subclass of: calcium channel blocker
definition: Any agent that interferes with the activity of T-type calcium channels.
id: CHEBI:194338
database_cross_reference: PMID:30372652
database_cross_reference: PMID:36738196
has_related_synonym: T-type calcium channel antagonist
has_related_synonym: T-type calcium channel antagonists
has_related_synonym: T-type calcium channel blockers
database_cross_reference: Wikipedia:T-type_calcium_channel
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

aquaretic
type: Class
subclass of: diuretic
definition: A class of diuretics which promote aquaresis (the excretion of water without electrolyte loss).
id: CHEBI:194423
database_cross_reference: PMID:12107918
database_cross_reference: PMID:17430186
database_cross_reference: PMID:21088744
database_cross_reference: PMID:24853354
database_cross_reference: PMID:28194573
database_cross_reference: PMID:28652798
database_cross_reference: PMID:29259382
database_cross_reference: PMID:36156485
database_cross_reference: PMID:8738740
database_cross_reference: PMID:8998673
database_cross_reference: Wikipedia:Aquaretic
has_related_synonym: aquaretic agent
has_related_synonym: aquaretic agents
has_related_synonym: aquaretics
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

antimyopathic agent
type: Class
subclass of: drug
definition: A drug used to treat myopathy.
id: CHEBI:194430
database_cross_reference: Wikipedia:Myopathy
has_related_synonym: antimyopathic agents
has_related_synonym: antimyopathic drug
has_related_synonym: antimyopathic drugs
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

NOD1 agonist
type: Class
subclass of: agonist
definition: An agonist that activates NOD1 receptors.
has_related_synonym: CARD4 agonist
has_related_synonym: CARD4 agonists
id: CHEBI:194467
has_related_synonym: CLR7.1 agonist
has_related_synonym: CLR7.1 agonists
has_related_synonym: NOD1 agonists
database_cross_reference: Wikipedia:NOD1
has_related_synonym: caspase recruitment domain-containing protein 4 agonist
has_related_synonym: caspase recruitment domain-containing protein 4 agonists
has_obo_namespace: chebi_ontology
has_related_synonym: nucleotide binding oligomerization domain containing 1 agonist
has_related_synonym: nucleotide binding oligomerization domain containing 1 agonists
has_related_synonym: nucleotide-binding oligomerization domain-containing protein 1 agonist
has_related_synonym: nucleotide-binding oligomerization domain-containing protein 1 agonists
in_subset: 3 STAR
imported from: chebi.owl

activator
type: Class
subclass of: biological role
definition: A substance that increases the rate of a chemical reaction.
id: CHEBI:195251
has_related_synonym: activators
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

enzyme activator
type: Class
subclass of: activator
subclass of: biochemical role
definition: An activator of an enzyme-catalysed reaction.
id: CHEBI:195252
database_cross_reference: Wikipedia:Enzyme_activator
has_obo_namespace: chebi_ontology
has_related_synonym: enzyme activators
in_subset: 3 STAR
imported from: chebi.owl

EC 2.6.1.13 (ornithine aminotransferase) inhibitor
type: Class
subclass of: EC 2.6.1.* (transaminase) inhibitor
definition: An EC 2.6.1.* (transaminase) inhibitor that interferes with the action of ornithine aminotransferase (EC 2.6.1.13).
id: CHEBI:195331
has_related_synonym: EC 2.6.1.13 (ornithine aminotransferase) inhibitors
has_related_synonym: EC 2.6.1.13 inhibitor
has_related_synonym: EC 2.6.1.13 inhibitors
has_related_synonym: L-ornithine 5-aminotransferase inhibitor
has_related_synonym: L-ornithine 5-aminotransferase inhibitors
has_related_synonym: L-ornithine aminotransferase inhibitor
has_related_synonym: L-ornithine aminotransferase inhibitors
has_related_synonym: L-ornithine:alpha-ketoglutarate -aminotransferase inhibitor
has_related_synonym: L-ornithine:alpha-ketoglutarate -aminotransferase inhibitors
has_related_synonym: OAT inhibitor
has_related_synonym: OAT inhibitors
database_cross_reference: Wikipedia:Ornithine_aminotransferase
has_obo_namespace: chebi_ontology
has_related_synonym: ornithine 5-aminotransferase inhibitor
has_related_synonym: ornithine 5-aminotransferase inhibitors
has_related_synonym: ornithine aminotransferase inhibitor
has_related_synonym: ornithine aminotransferase inhibitors
has_related_synonym: ornithine delta-transaminase inhibitor
has_related_synonym: ornithine delta-transaminase inhibitors
has_related_synonym: ornithine transaminase inhibitor
has_related_synonym: ornithine transaminase inhibitors
has_related_synonym: ornithine--oxo-acid transaminase inhibitor
has_related_synonym: ornithine--oxo-acid transaminase inhibitors
has_related_synonym: ornithine-2-oxoacid aminotransferase inhibitor
has_related_synonym: ornithine-2-oxoacid aminotransferase inhibitors
has_related_synonym: ornithine-alpha-ketoglutarate aminotransferase inhibitor
has_related_synonym: ornithine-alpha-ketoglutarate aminotransferase inhibitors
has_related_synonym: ornithine-keto acid aminotransferase inhibitor
has_related_synonym: ornithine-keto acid aminotransferase inhibitors
has_related_synonym: ornithine-keto acid transaminase inhibitor
has_related_synonym: ornithine-keto acid transaminase inhibitors
has_related_synonym: ornithine-ketoglutarate aminotransferase inhibitor
has_related_synonym: ornithine-ketoglutarate aminotransferase inhibitors
has_related_synonym: ornithine-oxo acid aminotransferase inhibitor
has_related_synonym: ornithine-oxo acid aminotransferase inhibitors
has_related_synonym: ornithine:alpha-oxoglutarate transaminase inhibitor
has_related_synonym: ornithine:alpha-oxoglutarate transaminase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

insulin-like growth factor-binding protein inhibitor
type: Class
subclass of: inhibitor
definition: Any inhibitor that acts on insulin-like growth factor-binding proteins.
id: CHEBI:195444
has_related_synonym: IGFBP inhibitor
has_related_synonym: IGFBP inhibitors
database_cross_reference: Wikipedia:Insulin-like_growth_factor-binding_protein
has_obo_namespace: chebi_ontology
has_related_synonym: insulin-like growth factor-binding protein inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.12.1 (dual-specificity kinase) inhibitor
type: Class
subclass of: EC 2.7.12.* [dual-specificity kinases (those acting on Ser/Thr and Tyr residues)] inhibitor
has_related_synonym: ADK1 inhibitor
has_related_synonym: ADK1 inhibitors
definition: An EC 2.7.12.* [dual-specificity kinases (those acting on Ser/Thr and Tyr residues)] inhibitor that inhibits the action of dual-specificity kinase (EC 2.7.12.1).
has_related_synonym: Arabidopsis dual specificity kinase 1 inhibitor
has_related_synonym: Arabidopsis dual specificity kinase 1 inhibitors
id: CHEBI:195525
has_related_synonym: CLK1 inhibitor
has_related_synonym: CLK1 inhibitors
has_related_synonym: EC 2.7.12.1 (dual-specificity kinase) inhibitors
has_related_synonym: EC 2.7.12.1 inhibitor
has_related_synonym: EC 2.7.12.1 inhibitors
has_related_synonym: Mps1p inhibitor
has_related_synonym: Mps1p inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: dDYRK2 inhibitor
has_related_synonym: dDYRK2 inhibitors
has_related_synonym: dual-specificity kinase inhibitor
has_related_synonym: dual-specificity kinase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

PCNA inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
definition: An inhibitor that interferes with the action of PCNA.
id: CHEBI:195530
has_related_synonym: PCNA inhibitors
database_cross_reference: PMID:25729582
database_cross_reference: PMID:37486931
database_cross_reference: PMID:37511614
database_cross_reference: Wikipedia:Proliferating_cell_nuclear_antigen
has_obo_namespace: chebi_ontology
has_related_synonym: proliferating cell nuclear antigen inhibitor
has_related_synonym: proliferating cell nuclear antigen inhibitors
in_subset: 3 STAR
imported from: chebi.owl

sphingosine-1-phosphate receptor 2 antagonist
type: Class
subclass of: sphingosine-1-phosphate receptor antagonist
definition: Any sphingosine-1-phosphate receptor (S1PR) antagonist that acts as an antagonist for the subtype 2 receptors (S1PR2).
id: CHEBI:195542
has_related_synonym: EDG-5 antagonist
has_related_synonym: EDG-5 antagonists
has_related_synonym: EDG5 antagonist
has_related_synonym: EDG5 antagonists
database_cross_reference: PMID:25746814
database_cross_reference: PMID:26384288
database_cross_reference: PMID:26794040
database_cross_reference: PMID:28676392
database_cross_reference: PMID:34411894
database_cross_reference: PMID:36527992
has_related_synonym: S1P2 antagonist
has_related_synonym: S1P2 antagonists
has_related_synonym: S1PR2 antagonist
has_related_synonym: S1PR2 antagonists
database_cross_reference: Wikipedia:S1PR2
has_obo_namespace: chebi_ontology
has_related_synonym: sphingosine-1-phosphate receptor 2 antagonists
in_subset: 3 STAR
imported from: chebi.owl

EC 3.5.3.1 (arginase) inhibitor
type: Class
subclass of: EC 3.5.3.* (non-peptide linear amidine C-N hydrolase) inhibitor
definition: An EC 3.5.3.* (non-peptide linear amidine C-N hydrolase) inhibitor that interferes with the action of arginase (EC 3.5.3.1).
id: CHEBI:195561
has_related_synonym: EC 3.5.3.1 (arginase) inhibitors
has_related_synonym: EC 3.5.3.1 inhibitor
has_related_synonym: EC 3.5.3.1 inhibitors
has_related_synonym: L-arginase inhibitor
has_related_synonym: L-arginase inhibitors
database_cross_reference: Wikipedia:Arginase
has_related_synonym: arginase inhibitor
has_related_synonym: arginase inhibitors
has_related_synonym: arginine amidinase inhibitor
has_related_synonym: arginine amidinase inhibitors
has_related_synonym: arginine transamidinase inhibitor
has_related_synonym: arginine transamidinase inhibitors
has_related_synonym: canavanase inhibitor
has_related_synonym: canavanase inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 3.5.3.* (non-peptide linear amidine C-N hydrolase) inhibitor
type: Class
subclass of: EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor
definition: An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide linear amidine C-N hydrolase (EC 3.5.3.*).
id: CHEBI:195562
has_related_synonym: EC 3.5.3.* (non-peptide linear amidine C-N hydrolase) inhibitors
has_related_synonym: EC 3.5.3.* inhibitor
has_related_synonym: EC 3.5.3.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: non-peptide linear amidine C-N hydrolase (EC 3.5.3.*) inhibitor
has_related_synonym: non-peptide linear amidine C-N hydrolase (EC 3.5.3.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

calcitonin gene-related peptide receptor antagonist
type: Class
subclass of: G-protein-coupled receptor antagonist
definition: An antagonist at any calcitonin gene-related peptide receptor.
has_related_synonym: CGRP antagonist
has_related_synonym: CGRP antagonists
id: CHEBI:196956
database_cross_reference: Wikipedia:Calcitonin_gene-related_peptide_receptor_antagonist
has_related_synonym: calcitonin gene-related peptide receptor antagonists
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

Rac1 inhibitor
type: Class
subclass of: inhibitor
definition: Any inhibitor of Rac1.
id: CHEBI:197347
database_cross_reference: PMID:19527032
has_related_synonym: Rac-1 inhibitor
has_related_synonym: Rac-1 inhibitors
has_related_synonym: Rac1 inhibitors
has_related_synonym: Ras-related C3 botulinum toxin substrate 1 inhibitor
has_related_synonym: Ras-related C3 botulinum toxin substrate 1 inhibitors
database_cross_reference: Wikipedia:RAC1
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

NMR solvent
type: Class
subclass of: solvent
definition: A solvent used in nuclear magnetic resonance (NMR) spectroscopy.
id: CHEBI:197449
has_related_synonym: NMR solvents
has_related_synonym: NMR-Loesemittel
has_related_synonym: NMR-Loesungsmittel
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 2.5.1.19 (3-phosphoshikimate 1-carboxyvinyltransferase) inhibitor
type: Class
subclass of: EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor
has_related_synonym: 3-enol-pyruvoylshikimate-5-phosphate synthase inhibitor
has_related_synonym: 3-enol-pyruvoylshikimate-5-phosphate synthase inhibitors
has_related_synonym: 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) inhibitor
has_related_synonym: 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) inhibitors
has_related_synonym: 3-phosphoshikimate 1-carboxyvinyltransferase inhibitor
has_related_synonym: 3-phosphoshikimate 1-carboxyvinyltransferase inhibitors
has_related_synonym: 5-enolpyruvylshikimate-3-phosphate synthase inhibitor
has_related_synonym: 5-enolpyruvylshikimate-3-phosphate synthase inhibitors
definition: An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19).
id: CHEBI:20569
has_related_synonym: EC 2.5.1.19 (3-phosphoshikimate 1-carboxyvinyltransferase) inhibitors
has_related_synonym: EC 2.5.1.19 inhibitor
has_related_synonym: EC 2.5.1.19 inhibitors
has_related_synonym: EPSP synthase inhibitor
has_related_synonym: EPSP synthase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: phosphoenolpyruvate:3-phosphoshikimate 5-O-(1-carboxyvinyl)-transferase inhibitor
has_related_synonym: phosphoenolpyruvate:3-phosphoshikimate 5-O-(1-carboxyvinyl)-transferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

ATP synthase inhibitor
type: Class
subclass of: mitochondrial respiratory-chain inhibitor
subclass of: EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor
definition: A mitochondrial respiratory-chain inhibitor that interferes with the action of ATP synthase.
id: CHEBI:20854
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

acaricide
type: Class
subclass of: pesticide
definition: A substance used to destroy pests of the subclass Acari (mites and ticks).
has_related_synonym: Akarizid
has_related_synonym: Akarizide
id: CHEBI:22153
database_cross_reference: Wikipedia:Acaricide
has_related_synonym: acaricides
has_obo_namespace: chebi_ontology
has_related_synonym: miticide
in_subset: 3 STAR
imported from: chebi.owl

EC 2.2.1.6 (acetolactate synthase) inhibitor
type: Class
subclass of: EC 2.2.1.* (transketolase/transaldolase) inhibitor
definition: An EC 2.2.1.* (transketolase/transaldolase) inhibitor that interferes with the action of acetolactate synthase (EC 2.2.1.6).
id: CHEBI:22180
has_related_synonym: EC 2.2.1.6 (acetolactate synthase) inhibitors
has_related_synonym: EC 2.2.1.6 inhibitor
has_related_synonym: EC 2.2.1.6 inhibitors
database_cross_reference: Wikipedia:Acetolactate_synthase
has_related_synonym: acetohydroxy acid synthetase inhibitor
has_related_synonym: acetohydroxy acid synthetase inhibitors
has_related_synonym: acetohydroxyacid synthase inhibitor
has_related_synonym: acetohydroxyacid synthase inhibitors
has_related_synonym: acetolactate pyruvate-lyase (carboxylating) inhibitor
has_related_synonym: acetolactate pyruvate-lyase (carboxylating) inhibitors
has_related_synonym: acetolactate synthase (EC 2.2.1.6) inhibitor
has_related_synonym: acetolactate synthase (EC 2.2.1.6) inhibitors
has_related_synonym: acetolactate synthase inhibitor
has_related_synonym: acetolactate synthase inhibitors
has_related_synonym: acetolactic synthetase inhibitor
has_related_synonym: acetolactic synthetase inhibitors
has_related_synonym: alpha-acetohydroxy acid synthetase inhibitor
has_related_synonym: alpha-acetohydroxy acid synthetase inhibitors
has_related_synonym: alpha-acetohydroxyacid synthase inhibitor
has_related_synonym: alpha-acetohydroxyacid synthase inhibitors
has_related_synonym: alpha-acetolactate synthase inhibitor
has_related_synonym: alpha-acetolactate synthase inhibitors
has_related_synonym: alpha-acetolactate synthetase inhibitor
has_related_synonym: alpha-acetolactate synthetase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: pyruvate:pyruvate acetaldehydetransferase (decarboxylating) inhibitor
has_related_synonym: pyruvate:pyruvate acetaldehydetransferase (decarboxylating) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

alicyclic antibiotics
type: Class
subclass of: antimicrobial agent
id: CHEBI:22309
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

aliphatic antibiotics
type: Class
subclass of: antimicrobial agent
id: CHEBI:22311
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

alkylating agent
type: Class
subclass of: mutagen
id: CHEBI:22333
definition: Highly reactive chemical that introduces alkyl radicals into biologically active molecules and thereby prevents their proper functioning. It could be used as an antineoplastic agent, but it might be very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. It could also be used as a component of poison gases.
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

alpha-1-microglobulin-Ig alpha complex chromophores
type: Class
subclass of: chromophore
id: CHEBI:22368
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

amino acid derivative antibiotics
type: Class
subclass of: antimicrobial agent
id: CHEBI:22476
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

antiauxins
type: Class
subclass of: plant growth regulator
id: CHEBI:22581
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

antifeedant
type: Class
subclass of: pesticide
definition: A substance that prevents pests from feeding.
id: CHEBI:22583
has_related_synonym: antifeedants
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

antioxidant
type: Class
subclass of: chemical role
definition: A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides.
id: CHEBI:22586
has_related_synonym: antioxidants
has_related_synonym: antioxydant
has_related_synonym: antoxidant
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

antiviral agent
type: Class
subclass of: antimicrobial agent
definition: A substance that destroys or inhibits replication of viruses.
id: CHEBI:22587
has_related_synonym: anti-viral agent
has_related_synonym: anti-viral agents
has_related_synonym: antiviral
has_related_synonym: antiviral agents
has_related_synonym: antivirals
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

auxin
type: Class
subclass of: plant hormone
definition: Any of a group of compounds, both naturally occurring and synthetic, that induce cell elongation in plant stems (from Greek alphaupsilonxialphanuomega, "to grow").
id: CHEBI:22676
database_cross_reference: Wikipedia:Auxin
has_related_synonym: auxins
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

base
type: Class
subclass of: chemical role
definition: A molecular entity having an available pair of electrons capable of forming a covalent bond with a hydron (Bronsted base) or with the vacant orbital of some other molecular entity (Lewis base).
has_exact_synonym: Base
has_related_synonym: Base1
has_related_synonym: Base2
has_related_synonym: Basen
id: CHEBI:22695
database_cross_reference: KEGG:C00701
has_related_synonym: Nucleobase
has_exact_synonym: base
has_related_synonym: bases
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

antinociceptive agent
type: Class
subclass of: drug
subclass of: pharmacological role
definition: Any agent that inhibits nociception.
id: CHEBI:228138
database_cross_reference: PMID:37851902
has_related_synonym: antinociceptive agents
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

C3a receptor antagonist
type: Class
subclass of: G-protein-coupled receptor antagonist
definition: Any antagonist of the C3a receptor.
has_related_synonym: C3AR1 antagonist
has_related_synonym: C3AR1 antagonists
has_related_synonym: C3a receptor antagonists
id: CHEBI:228139
database_cross_reference: Wikipedia:C3a_receptor
has_obo_namespace: chebi_ontology
has_related_synonym: complement component 3a receptor 1 antagonist
has_related_synonym: complement component 3a receptor 1 antagonists
in_subset: 3 STAR
imported from: chebi.owl

sigma-1 receptor agonist
type: Class
subclass of: sigma receptor modulator
definition: A sigma receptor modulator that activates the sigma-1 receptor.
id: CHEBI:228237
database_cross_reference: Wikipedia:Sigma-1_receptor
has_obo_namespace: chebi_ontology
has_related_synonym: sigma 1 receptor agonist
has_related_synonym: sigma 1 receptor agonists
has_related_synonym: sigma-1 receptor agonists
has_related_synonym: sigma1 receptor agonist
has_related_synonym: sigma1 receptor agonists
has_related_synonym: sigma1R agonist
has_related_synonym: sigma1R agonists
in_subset: 3 STAR
imported from: chebi.owl

PNU-74654
type: Class
subclass of: Wnt signalling inhibitor
charge: 0
monoisotopicmass: 320.11609
mass: 320.348
has_related_synonym: Benzoic acid, 2-phenoxy-, 2-[(5-methyl-2-furanyl)methylene]hydrazide
formula: C19H16N2O3
database_cross_reference: CAS:113906-27-7
id: CHEBI:228251
inchi: InChI=1S/C19H16N2O3/c1-14-11-12-16(23-14)13-20-21-19(22)17-9-5-6-10-18(17)24-15-7-3-2-4-8-15/h2-13H,1H3,(H,21,22)/b20-13+
inchikey: JJEDWBQZCRESJL-DEDYPNTBSA-N
has_related_synonym: PNU 74654
has_related_synonym: PNU74654
definition: beta-catenin - TCF interaction inhibitor
has_obo_namespace: chebi_ontology
in_subset: 2 STAR
imported from: chebi.owl

EC 2.1.1.354 ([histone H3]-lysine(4) N-trimethyltransferase) inhibitor
type: Class
subclass of: EC 2.1.1.* (methyltransferases) inhibitor
has_related_synonym: ASH1L inhibitor
has_related_synonym: ASH1L inhibitors
definition: An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of [histone H3]-lysine(4) N-trimethyltransferase (EC 2.1.1.354).
id: CHEBI:228263
has_related_synonym: EC 2.1.1.354 ([histone H3]-lysine(4) N-trimethyltransferase) inhibitors
has_related_synonym: EC 2.1.1.354 inhibitor
has_related_synonym: EC 2.1.1.354 inhibitors
has_related_synonym: KMT2H inhibitor
has_related_synonym: KMT2H inhibitors
has_related_synonym: KMT3C inhibitor
has_related_synonym: KMT3C inhibitors
has_related_synonym: KMT3D inhibitor
has_related_synonym: KMT3D inhibitors
has_related_synonym: KMT3E inhibitor
has_related_synonym: KMT3E inhibitors
has_related_synonym: MLL5 inhibitor
has_related_synonym: MLL5 inhibitors
has_related_synonym: PRDM9 inhibitor
has_related_synonym: PRDM9 inhibitors
has_related_synonym: SMYD1 inhibitor
has_related_synonym: SMYD1 inhibitors
has_related_synonym: SMYD2 inhibitor
has_related_synonym: SMYD2 inhibitors
has_related_synonym: SMYD3 inhibitor
has_related_synonym: SMYD3 inhibitors
has_related_synonym: [histone H3]-lysine(4) N-trimethyltransferase inhibitor
has_related_synonym: [histone H3]-lysine(4) N-trimethyltransferase inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

WNK signaling inhibitor
type: Class
subclass of: inhibitor
definition: A substance that inhibits any of the WNK signalling pathway.
id: CHEBI:228284
database_cross_reference: PMID:28566208
database_cross_reference: PMID:28881465
has_related_synonym: WNK signaling inhibitors
has_related_synonym: WNK signalling inhibitor
has_related_synonym: WNK signalling inhibitors
has_related_synonym: WNK-signaling inhibitor
has_related_synonym: WNK-signaling inhibitors
has_related_synonym: WNK-signalling inhibitor
has_related_synonym: WNK-signalling inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: lysine deficient protein kinase (WNK) signaling inhibitor
has_related_synonym: lysine deficient protein kinase (WNK) signaling inhibitors
has_related_synonym: with no lysine [K] (WNK) pathway inhibitor
has_related_synonym: with no lysine [K] (WNK) pathway inhibitors
has_related_synonym: with-no-lysine (WNK) protein kinase signaling inhibitor
has_related_synonym: with-no-lysine (WNK) protein kinase signaling inhibitors
in_subset: 3 STAR
imported from: chebi.owl

trace amine-associated receptor 1 agonist
type: Class
subclass of: G-protein-coupled receptor agonist
definition: An agonist that selectively binds to and activates trace amine-associated receptor 1.
id: CHEBI:228347
has_related_synonym: TA1 receptor agonist
has_related_synonym: TA1 receptor agonists
has_related_synonym: TAAR1 agonist
has_related_synonym: TAAR1 agonists
database_cross_reference: Wikipedia:TAAR1
has_obo_namespace: chebi_ontology
has_related_synonym: trace amine 1 (TA1) receptor agonist
has_related_synonym: trace amine 1 (TA1) receptor agonists
has_related_synonym: trace amine 1 receptor agonist
has_related_synonym: trace amine 1 receptor agonists
has_related_synonym: trace amine associated receptor 1 agonist
has_related_synonym: trace amine associated receptor 1 agonists
has_related_synonym: trace amine-associated receptor 1 agonists
in_subset: 3 STAR
imported from: chebi.owl

NMR chemical shift reference compound
type: Class
subclass of: application
subclass of: chemical role
definition: Any compound that produces a peak used as reference frequency in the delta chemical shift scale.
id: CHEBI:228364
has_related_synonym: NMR chemical shift reference compounds
has_related_synonym: NMR chemical shift standard
has_related_synonym: NMR chemical shift standards
has_related_synonym: NMR internal standard
has_related_synonym: NMR internal standards
has_related_synonym: NMR reference standard
has_related_synonym: NMR reference standards
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

heat shock factor 1 inhibitor
type: Class
subclass of: inhibitor
definition: Any inhibitor that interferes with the action of heat shock factor 1.
id: CHEBI:228801
has_related_synonym: HSF 1 inhibitor
has_related_synonym: HSF 1 inhibitors
has_related_synonym: HSF-1 inhibitor
has_related_synonym: HSF-1 inhibitors
has_related_synonym: HSF1 inhibitor
has_related_synonym: HSF1 inhibitors
database_cross_reference: Wikipedia:HSF1
has_obo_namespace: chebi_ontology
has_related_synonym: heat shock factor 1 inhibitors
has_related_synonym: heat shock factor protein 1 inhibitor
has_related_synonym: heat shock factor protein 1 inhibitors
has_related_synonym: heat shock factor-1 inhibitor
has_related_synonym: heat shock factor-1 inhibitors
in_subset: 3 STAR
imported from: chebi.owl

phytogenic insecticide
type: Class
subclass of: insecticide
definition: An insecticide compound naturally occurring in plants.
id: CHEBI:22917
has_related_synonym: botanical insecticide
has_related_synonym: botanical insecticides
has_obo_namespace: chebi_ontology
has_related_synonym: phytogenic insecticides
in_subset: 3 STAR
imported from: chebi.owl

sodium-glucose transport protein subtype 1 inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
definition: Any inhibitor that interferes with the action of sodium-glucose transport protein subtype 1.
id: CHEBI:229227
has_related_synonym: SGLT1 inhibitor
has_related_synonym: SGLT1 inhibitors
database_cross_reference: Wikipedia:Sodium/glucose_cotransporter_1
has_obo_namespace: chebi_ontology
has_related_synonym: sodium glucose co-transporter 1 inhibitor
has_related_synonym: sodium glucose co-transporter 1 inhibitors
has_related_synonym: sodium-glucose transport protein subtype 1 inhibitors
has_related_synonym: sodium/glucose cotransporter 1 inhibitor
has_related_synonym: sodium/glucose cotransporter 1 inhibitors
has_related_synonym: solute carrier family 5 member 1 inhibitor
has_related_synonym: solute carrier family 5 member 1 inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.1.153 (phosphatidylinositol-4,5-bisphosphate 3-kinase) inhibitor
type: Class
subclass of: EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor
has_related_synonym: ATP:1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 3-phosphotransferase inhibitor
has_related_synonym: ATP:1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 3-phosphotransferase inhibitors
definition: Any EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor that interferes with the action of phosphatidylinositol-4,5-bisphosphate 3-kinase (EC 2.7.1.153).
id: CHEBI:229651
has_related_synonym: EC 2.7.1.153 inhibitor
has_related_synonym: EC 2.7.1.153 inhibitors
database_cross_reference: Wikipedia:Phosphatidylinositol-4,5-bisphosphate_3-kinase
has_obo_namespace: chebi_ontology
has_related_synonym: phosphatidylinositol-4,5-bisphosphate 3-kinase inhibitor
has_related_synonym: phosphatidylinositol-4,5-bisphosphate 3-kinase inhibitors
has_related_synonym: type I phosphoinositide 3-kinase inhibitor
has_related_synonym: type I phosphoinositide 3-kinase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

complement factor B inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
definition: Any inhibitor of complement factor B.
has_related_synonym: CFB inhibitor
has_related_synonym: CFB inhibitors
id: CHEBI:229655
database_cross_reference: Wikipedia:Complement_factor_B
has_obo_namespace: chebi_ontology
has_related_synonym: complement factor B inhibitors
in_subset: 3 STAR
imported from: chebi.owl

complement component 5 inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
definition: Any inhibitor of complement component 5.
has_related_synonym: C5 inhibitor
has_related_synonym: C5 inhibitors
id: CHEBI:229668
database_cross_reference: Wikipedia:Complement_component_5
has_obo_namespace: chebi_ontology
has_related_synonym: complement component 5 inhibitors
in_subset: 3 STAR
imported from: chebi.owl

IAP antagonist
type: Class
subclass of: antagonist
definition: An antagonist of the inhibitor of apoptosis proteins. Inhibitors of apoptosis proteins (IAP) are a family of functionally and structurally related proteins that serve as endogenous inhibitors of programmed cell death (apoptosis).
id: CHEBI:229692
has_related_synonym: IAP antagonists
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of apoptosis protein antagonist
has_related_synonym: inhibitor of apoptosis protein antagonists
in_subset: 3 STAR
imported from: chebi.owl

exportin 1 inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
definition: Any inhibitor of exportin 1.
id: CHEBI:229763
has_related_synonym: CRM-1 inhibitor
has_related_synonym: CRM-1 inhibitors
has_related_synonym: CRM1 inhibitor
has_related_synonym: CRM1 inhibitors
database_cross_reference: PMID:37595020
database_cross_reference: PMID:37899423
database_cross_reference: PMID:38105606
has_related_synonym: SINE compound
has_related_synonym: SINE compounds
has_related_synonym: SINEs
database_cross_reference: Wikipedia:XPO1
has_related_synonym: XPO1 inhibitor
has_related_synonym: XPO1 inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: chromosomal region maintenance 1 inhibitor
has_related_synonym: chromosomal region maintenance 1 inhibitors
has_related_synonym: exportin 1 inhibitors
has_related_synonym: exportin-1 inhibitor
has_related_synonym: exportin-1 inhibitors
has_related_synonym: selective inhibitor of nuclear export
has_related_synonym: selective inhibitors of nuclear export
in_subset: 3 STAR
imported from: chebi.owl

glucose transporter inhibitor
type: Class
subclass of: inhibitor
definition: Any substance that inhibits the action of glucose transporters.
id: CHEBI:229782
database_cross_reference: Wikipedia:Glucose_transporter
has_obo_namespace: chebi_ontology
has_related_synonym: glucose transporter inhibitors
in_subset: 3 STAR
imported from: chebi.owl

glucose transporter 1 inhibitor
type: Class
subclass of: glucose transporter inhibitor
definition: Any glucose transporter inhibitor that interferes with the action of glucose transporter 1.
id: CHEBI:229783
has_related_synonym: GLUT1 inhibitor
has_related_synonym: GLUT1 inhibitors
has_related_synonym: SLC2A1 inhibitor
has_related_synonym: SLC2A1 inhibitors
database_cross_reference: Wikipedia:GLUT1
has_obo_namespace: chebi_ontology
has_related_synonym: glucose transporter 1 inhibitors
has_related_synonym: solute carrier family 2, facilitated glucose transporter member 1 inhibitor
has_related_synonym: solute carrier family 2, facilitated glucose transporter member 1 inhibitors
in_subset: 3 STAR
imported from: chebi.owl

calcium ionophore
type: Class
subclass of: ionophore
id: CHEBI:22986
has_related_synonym: calcium ionophores
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 4.2.1.1 (carbonic anhydrase) inhibitor
type: Class
subclass of: EC 4.2.1.* (hydro-lyases) inhibitor
definition: An EC 4.2.1.* (hydro-lyases) inhibitor that interferes with the action of carbonic anhydrase (EC 4.2.1.1). Such compounds reduce the secretion of H(+) ions by the proximal kidney tubule.
id: CHEBI:23018
has_related_synonym: EC 4.2.1.1 (carbonic anhydrase) inhibitors
has_related_synonym: EC 4.2.1.1 inhibitor
has_related_synonym: EC 4.2.1.1 inhibitors
database_cross_reference: Wikipedia:Carbonic_anhydrase_inhibitor
has_related_synonym: anhydrase inhibitor
has_related_synonym: anhydrase inhibitors
has_related_synonym: carbonate anhydrase inhibitor
has_related_synonym: carbonate anhydrase inhibitors
has_related_synonym: carbonate dehydratase inhibitor
has_related_synonym: carbonate dehydratase inhibitors
has_related_synonym: carbonate hydro-lyase (carbon-dioxide-forming) inhibitor
has_related_synonym: carbonate hydro-lyase (carbon-dioxide-forming) inhibitors
has_related_synonym: carbonate hydro-lyase inhibitor
has_related_synonym: carbonate hydro-lyase inhibitors
has_related_synonym: carbonic acid anhydrase inhibitor
has_related_synonym: carbonic acid anhydrase inhibitors
has_related_synonym: carbonic anhydrase (EC 4.2.1.1) inhibitor
has_related_synonym: carbonic anhydrase (EC 4.2.1.1) inhibitors
has_related_synonym: carbonic anhydrase A inhibitor
has_related_synonym: carbonic anhydrase A inhibitors
has_related_synonym: carbonic anhydrase inhibitor
has_related_synonym: carbonic anhydrase inhibitors
has_related_synonym: carboxyanhydrase inhibitor
has_related_synonym: carboxyanhydrase inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 2.4.1.34 (1,3-beta-glucan synthase) inhibitor
type: Class
subclass of: EC 2.4.1.* (hexosyltransferase) inhibitor
has_related_synonym: (1,3)-beta-glucan (callose) synthase inhibitor
has_related_synonym: (1,3)-beta-glucan (callose) synthase inhibitors
has_related_synonym: 1,3-beta-D-glucan synthase inhibitor
has_related_synonym: 1,3-beta-D-glucan synthase inhibitors
has_related_synonym: 1,3-beta-D-glucan synthetase inhibitor
has_related_synonym: 1,3-beta-D-glucan synthetase inhibitors
has_related_synonym: 1,3-beta-D-glucan--UDP glucosyltransferase inhibitor
has_related_synonym: 1,3-beta-D-glucan--UDP glucosyltransferase inhibitors
has_related_synonym: 1,3-beta-D-glucan-UDP glucosyltransferase inhibitor
has_related_synonym: 1,3-beta-D-glucan-UDP glucosyltransferase inhibitors
has_related_synonym: 1,3-beta-glucan synthase inhibitor
has_related_synonym: 1,3-beta-glucan synthase inhibitors
has_related_synonym: 1,3-beta-glucan-uridine diphosphoglucosyltransferase inhibitor
has_related_synonym: 1,3-beta-glucan-uridine diphosphoglucosyltransferase inhibitors
definition: A EC 2.4.1.* (hexosyltransferase) inhibitor that inhibits the action of 1,3-beta-glucan synthase (EC 2.4.1.34).
id: CHEBI:230471
has_related_synonym: EC 2.4.1.34 (1,3-beta-glucan synthase) inhibitors
has_related_synonym: EC 2.4.1.34 inhibitor
has_related_synonym: EC 2.4.1.34 inhibitors
has_related_synonym: GS-II inhibitor
has_related_synonym: GS-II inhibitors
has_related_synonym: UDP-glucose--1,3-beta-D-glucan glucosyltransferase inhibitor
has_related_synonym: UDP-glucose--1,3-beta-D-glucan glucosyltransferase inhibitors
has_related_synonym: UDP-glucose-1,3-beta-D-glucan glucosyltransferase inhibitor
has_related_synonym: UDP-glucose-1,3-beta-D-glucan glucosyltransferase inhibitors
has_related_synonym: UDP-glucose-1,3-beta-glucan glucosyltransferase inhibitor
has_related_synonym: UDP-glucose-1,3-beta-glucan glucosyltransferase inhibitors
has_related_synonym: UDP-glucose-beta-glucan glucosyltransferase inhibitor
has_related_synonym: UDP-glucose-beta-glucan glucosyltransferase inhibitors
has_related_synonym: UDP-glucose:(1,3)beta-glucan synthase inhibitor
has_related_synonym: UDP-glucose:(1,3)beta-glucan synthase inhibitors
has_related_synonym: UDP-glucose:1,3-beta-D-glucan 3-beta-D-glucosyltransferase inhibitor
has_related_synonym: UDP-glucose:1,3-beta-D-glucan 3-beta-D-glucosyltransferase inhibitors
database_cross_reference: Wikipedia:1,3-Beta-glucan_synthase
has_related_synonym: beta-1,3-glucan synthase inhibitor
has_related_synonym: beta-1,3-glucan synthase inhibitors
has_related_synonym: beta-1,3-glucan synthetase inhibitor
has_related_synonym: beta-1,3-glucan synthetase inhibitors
has_related_synonym: callose synthase inhibitor
has_related_synonym: callose synthase inhibitors
has_related_synonym: callose synthetase inhibitor
has_related_synonym: callose synthetase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: paramylon synthetase inhibitor
has_related_synonym: paramylon synthetase inhibitors
has_related_synonym: uridine diphosphoglucose-1,3-beta-glucan glucosyltransferase inhibitor
has_related_synonym: uridine diphosphoglucose-1,3-beta-glucan glucosyltransferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

chemosterilant
type: Class
subclass of: pesticide
definition: A substance intended to sterilize any organism.
id: CHEBI:23092
database_cross_reference: Wikipedia:Chemosterilant
has_obo_namespace: chebi_ontology
has_related_synonym: chemosterilants
in_subset: 3 STAR
imported from: chebi.owl

chitin synthesis inhibitor
type: Class
subclass of: insect growth regulator
id: CHEBI:23100
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

EC 2.4.2.12 (nicotinamide phosphoribosyltransferase) inhibitor
type: Class
subclass of: EC 2.4.2.* (pentosyltransferase) inhibitor
definition: An EC 2.4.2.* (pentosyltransferase) inhibitor that interferes with the action of nicotinamide phosphoribosyltransferase (EC 2.4.2.12).
id: CHEBI:231708
has_related_synonym: EC 2.4.2.12 (nicotinamide phosphoribosyltransferase) inhibitor inhibitors
has_related_synonym: EC 2.4.2.12 inhibitor
has_related_synonym: EC 2.4.2.12 inhibitors
has_related_synonym: NAMPT inhibitor
has_related_synonym: NAMPT inhibitors
has_related_synonym: NAmPRTase inhibitor
has_related_synonym: NAmPRTase inhibitors
has_related_synonym: NMN pyrophosphorylase inhibitor
has_related_synonym: NMN pyrophosphorylase inhibitors
has_related_synonym: NMN synthetase inhibitor
has_related_synonym: NMN synthetase inhibitors
database_cross_reference: Wikipedia:Nicotinamide_phosphoribosyltransferase
has_obo_namespace: chebi_ontology
has_related_synonym: nicotinamide mononucleotide pyrophosphorylase inhibitor
has_related_synonym: nicotinamide mononucleotide pyrophosphorylase inhibitors
has_related_synonym: nicotinamide mononucleotide synthetase inhibitor
has_related_synonym: nicotinamide mononucleotide synthetase inhibitors
has_related_synonym: nicotinamide phosphoribosyltransferase inhibitor
has_related_synonym: nicotinamide phosphoribosyltransferase inhibitors
has_related_synonym: nicotinamide-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase inhibitor
has_related_synonym: nicotinamide-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

BET bromodomain inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
definition: Any inhibitor of BET proteins.
has_related_synonym: BET bromodomain inhibitors
has_related_synonym: BET inhibitor
has_related_synonym: BET inhibitors
has_related_synonym: Bromo- and Extra-Terminal domain inhibitor
has_related_synonym: Bromo- and Extra-Terminal domain inhibitors
id: CHEBI:231729
database_cross_reference: Wikipedia:BET_inhibitor
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

CXCR2 antagonist
type: Class
subclass of: antagonist
definition: An antagonist that blocks CXCR2.
id: CHEBI:231732
has_related_synonym: CXCR2 antagonists
has_related_synonym: IL8RB antagonist
has_related_synonym: IL8RB antagonists
database_cross_reference: PMID:35313168
database_cross_reference: PMID:36780833
database_cross_reference: Wikipedia:Interleukin_8_receptor,_beta
has_obo_namespace: chebi_ontology
has_related_synonym: chemokine receptor CXCR2 antagonist
has_related_synonym: chemokine receptor CXCR2 antagonists
has_related_synonym: interleukin 8 receptor, beta antagonist
has_related_synonym: interleukin 8 receptor, beta antagonists
in_subset: 3 STAR
imported from: chebi.owl

EC 1.3.1.6 (fumarate reductase (NADH)) inhibitor
type: Class
subclass of: EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor
definition: An EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of fumarate reductase (NADH) (EC 1.3.1.6).
id: CHEBI:231760
has_related_synonym: EC 1.3.1.6 (fumarate reductase (NADH)) inhibitors
has_related_synonym: EC 1.3.1.6 inhibitor
has_related_synonym: EC 1.3.1.6 inhibitors
has_related_synonym: NADH-dependent fumarate reductase inhibitor
has_related_synonym: NADH-dependent fumarate reductase inhibitors
has_related_synonym: NADH-fumarate reductase inhibitor
has_related_synonym: NADH-fumarate reductase inhibitors
database_cross_reference: Wikipedia:Fumarate_reductase_(NADH)
has_obo_namespace: chebi_ontology
has_related_synonym: fumarate reductase (NADH) inhibitor
has_related_synonym: fumarate reductase (NADH) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

convulsant
type: Class
subclass of: central nervous system drug
definition: A drug that induces seizures or increases their severity.
id: CHEBI:231761
database_cross_reference: Wikipedia:Convulsant
has_obo_namespace: chebi_ontology
has_related_synonym: convulsants
has_related_synonym: convulsive agent
has_related_synonym: convulsive agents
has_related_synonym: convulsive drug
has_related_synonym: convulsive drugs
in_subset: 3 STAR
imported from: chebi.owl

renoprotective agent
type: Class
subclass of: protective agent
definition: Any compound that is able to prevent damage to the kidneys.
id: CHEBI:231911
has_obo_namespace: chebi_ontology
has_related_synonym: renoprotective agents
has_related_synonym: renoprotector
in_subset: 3 STAR
imported from: chebi.owl

NLRP3 inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
definition: Any inhibitor of NLRP3.
id: CHEBI:231916
has_related_synonym: NACHT, LRR and PYD domains-containing protein 3 inhibitor
has_related_synonym: NACHT, LRR and PYD domains-containing protein 3 inhibitors
has_related_synonym: NALP3 inhibitor
has_related_synonym: NALP3 inhibitors
has_related_synonym: NLR family pyrin domain containing 3 inhibitor
has_related_synonym: NLR family pyrin domain containing 3 inhibitors
has_related_synonym: NLRP3 inhibitors
has_related_synonym: PYPAF1 inhibitor
has_related_synonym: PYPAF1 inhibitors
has_related_synonym: PYRIN-containing APAF1-like protein 1 inhibitor
has_related_synonym: PYRIN-containing APAF1-like protein 1 inhibitors
database_cross_reference: Wikipedia:NLRP3
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

alpha-bungarotoxin
type: Class
subclass of: toxin
charge: 0
has_exact_synonym: 2-[[(1R,3S,5R,7S,9R,11S,12S,14S,16R,18S,20R,21Z,24S,26R,28S,30R,31R,33S,35R,37S,42R,44S,46R,48S)-12-hydroxy-1,3,11,24,31,41,44-heptamethyl-39-oxo-2,6,10,15,19,25,29,34,38,43,47-undecaoxaundecacyclo[26.22.0.03,26.05,24.07,20.09,18.011,16.030,48.033,46.035,44.037,42]pentaconta-21,40-dien-14-yl]methyl]prop-2-enal
monoisotopicmass: 894.47656
mass: 895.096
formula: C50H70O14
database_cross_reference: CAS:11032-79-4
id: CHEBI:232110
inchi: InChI=1S/C50H70O14/c1-25(24-51)14-28-17-37(52)50(8)41(54-28)19-33-34(61-50)18-32-29(55-33)10-9-12-46(4)42(58-32)23-49(7)40(62-46)21-39-47(5,64-49)13-11-30-44(60-39)26(2)15-31-36(56-30)22-48(6)38(57-31)20-35-45(63-48)27(3)16-43(53)59-35/h9-10,16,24,26,28-42,44-45,52H,1,11-15,17-23H2,2-8H3/b10-9-/t26-,28+,29-,30+,31+,32+,33+,34-,35+,36-,37+,38-,39+,40-,41-,42-,44-,45-,46+,47-,48+,49+,50+/m1/s1
inchikey: LYTCVQQGCSNFJU-LKGYBJPKSA-N
has_exact_synonym: alpha-bungarotoxin
has_obo_namespace: chebi_ontology
in_subset: 2 STAR
imported from: chebi.owl

desnitro-imidacloprid
type: Class
subclass of: neonicotinoid insectide
charge: 0
has_exact_synonym: 1-[(6-chloropyridin-3-yl)methyl]-4,5-dihydroimidazol-2-amine
monoisotopicmass: 210.06722
mass: 210.670
smiles: C1=CC(Cl)=NC=C1CN2CCNC2=N
formula: C9H11ClN4
database_cross_reference: CAS:115970-17-7
id: CHEBI:232298
inchi: InChI=1S/C9H11ClN4/c10-8-2-1-7(5-13-8)6-14-4-3-12-9(14)11/h1-2,5H,3-4,6H2,(H2,11,12)
inchikey: UEQZFAGVRGWPDK-UHFFFAOYSA-N
database_cross_reference: Wikipedia:https://en.wikipedia.org/wiki/Desnitro-imidacloprid
has_obo_namespace: chebi_ontology
in_subset: 2 STAR
imported from: chebi.owl

heptacosa-7,11-diene
type: Class
subclass of: pheromone
charge: 0
monoisotopicmass: 376.40690
mass: 376.713
has_related_synonym: 7,11-heptacosadiene
formula: C27H52
smiles: CCCCCC/C=C/CC/C=C/CCCCCCCCCCCCCCC
id: CHEBI:232301
inchikey: RJYQFYALHBHYMG-IDQXUSCUSA-N
has_obo_namespace: chebi_ontology
in_subset: 2 STAR
imported from: chebi.owl

AR-9281
type: Class
subclass of: enzyme inhibitor
charge: 0
has_exact_synonym: 1-(1-acetylpiperidin-4-yl)-3-(1-adamantyl)urea
monoisotopicmass: 319.22598
mass: 319.449
has_related_synonym: APAU
formula: C18H29N3O2
database_cross_reference: CAS:913548-29-5
id: CHEBI:232302
database_cross_reference: HMDB:HMDB0259461
inchikey: HUDQLWBKJOMXSZ-UHFFFAOYSA-N
inchi: InChI=1S/C18H29N3O2/c1-12(22)21-4-2-16(3-5-21)19-17(23)20-18-9-13-6-14(10-18)8-15(7-13)11-18/h13-16H,2-11H2,1H3,(H2,19,20,23)
has_obo_namespace: chebi_ontology
in_subset: 2 STAR
imported from: chebi.owl

KPT-350
type: Class
subclass of: exportin 1 inhibitor
charge: 0
monoisotopicmass: 449.12864
mass: 449.357
inchikey: BGUKCLNXSXSYCZ-SNAWJCMRSA-N
formula: C18H17F6N5O2
database_cross_reference: CAS:1487117-71-4
id: CHEBI:232303
inchi: InChI=1S/C18H17F6N5O2/c1-16(2,3)15(31)27-26-13(30)4-5-29-9-25-14(28-29)10-6-11(17(19,20)21)8-12(7-10)18(22,23)24/h4-9H,1-3H3,(H,26,30)(H,27,31)/b5-4+
has_exact_synonym: N'-[3-[3-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-triazol-1-yl]prop-2-enoyl]-2,2-dimethylpropanehydrazide
has_obo_namespace: chebi_ontology
in_subset: 2 STAR
imported from: chebi.owl

CP-115953
type: Class
subclass of: topoisomerase inhibitor
charge: 0
has_exact_synonym: 1-cyclopropyl-6,8-difluoro-7-(4-hydroxyphenyl)-4-oxoquinoline-3-carboxylic acid
monoisotopicmass: 357.08126
mass: 357.313
formula: C19H13F2NO4
database_cross_reference: CAS:136440-70-5
id: CHEBI:232313
inchikey: ISQTYKAFNUVODK-UHFFFAOYSA-N
inchi: InChI=1S/C19H13F2NO4/c20-14-7-12-17(16(21)15(14)9-1-5-11(23)6-2-9)22(10-3-4-10)8-13(18(12)24)19(25)26/h1-2,5-8,10,23H,3-4H2,(H,25,26)
has_obo_namespace: chebi_ontology
in_subset: 2 STAR
imported from: chebi.owl

bathophenanthrolinedisulfonic acid disodium salt
type: Class
subclass of: iron chelator
charge: 0
monoisotopicmass: 554.01943
mass: 554.500
formula: C24H14N2O6S2.H2O.Na.Na
database_cross_reference: CAS:98645-86-4
id: CHEBI:232316
inchi: InChI=1S/C24H16N2O6S2.2Na.H2O/c27-33(28,29)19-13-25-23-17(21(19)15-7-3-1-4-8-15)11-12-18-22(16-9-5-2-6-10-16)20(34(30,31)32)14-26-24(18)23;;;/h1-14H,(H,27,28,29)(H,30,31,32);;;1H2/q;2*+1;/p-2
inchikey: XYCFSBXROICZOX-UHFFFAOYSA-L
has_related_synonym: bathophenanthrolinedisulfonic acid disodium salt hydrate
has_obo_namespace: chebi_ontology
in_subset: 2 STAR
imported from: chebi.owl

DUB-IN-2
type: Class
subclass of: EC 3.4.19.* (omega-peptidase) inhibitor
charge: 0
monoisotopicmass: 275.08071
mass: 275.271
formula: C15H9N5O
database_cross_reference: CAS:924296-19-5
smiles: CCO/N=C/1\C2=CC=CC=C2C3=C1N=C(C#N)C(C#N)=N3
id: CHEBI:232317
inchi: InChI=1S/C15H9N5O/c1-2-21-20-14-10-6-4-3-5-9(10)13-15(14)19-12(8-17)11(7-16)18-13/h3-6H,2H2,1H3/b20-14+
inchikey: VKVAJBRQGBRHIK-XSFVSMFZSA-N
has_obo_namespace: chebi_ontology
has_related_synonym: deubiquitinase inhibitor 2
in_subset: 2 STAR
imported from: chebi.owl

benzoquinonium dibromide
type: Class
subclass of: cholinergic antagonist
charge: 0
monoisotopicmass: 704.23005
mass: 706.608
formula: C34H48N4O2.BrH.BrH
smiles: CC[N+](CC)(CCC[N-]C1=CC(C(=CC1=O)[N-]CCC[N+](CC)(CC)CC2=CC=CC=C2)=O)CC3=CC=CC=C3.Br.Br
id: CHEBI:232337
inchikey: DVQZHWAYOLXTHE-UHFFFAOYSA-N
inchi: InChI=1S/C34H48N4O2.2BrH/c1-5-37(6-2,27-29-17-11-9-12-18-29)23-15-21-35-31-25-34(40)32(26-33(31)39)36-22-16-24-38(7-3,8-4)28-30-19-13-10-14-20-30;;/h9-14,17-20,25-26H,5-8,15-16,21-24,27-28H2,1-4H3;2*1H
database_cross_reference: PMID:31102763
has_exact_synonym: benzyl-[3-[[4-[3-[benzyl(diethyl)azaniumyl]propylamino]-3,6-dioxocyclohexa-1,4-dien-1-yl]amino]propyl]-diethylazanium;dibromide
has_obo_namespace: chebi_ontology
in_subset: 2 STAR
imported from: chebi.owl

methyllycaconitine citrate
type: Class
subclass of: nicotinic antagonist
charge: 0
monoisotopicmass: 874.37355
mass: 874.934
formula: C37H50N2O10.C6H8O7
database_cross_reference: CAS:112825-05-5
id: CHEBI:232340
inchikey: INBLZNJHDLEWPS-DDIMIZGISA-N
inchi: InChI=1S/C37H50N2O10.C6H8O7/c1-7-38-17-34(18-49-32(42)20-10-8-9-11-23(20)39-26(40)14-19(2)31(39)41)13-12-25(46-4)36-22-15-21-24(45-3)16-35(43,27(22)28(21)47-5)37(44,33(36)38)30(48-6)29(34)36;7-3(8)1-6(13,5(11)12)2-4(9)10/h8-11,19,21-22,24-25,27-30,33,43-44H,7,12-18H2,1-6H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/t19-,21+,22+,24-,25-,27+,28-,29+,30-,33?,34-,35+,36-,37+;/m0./s1
has_obo_namespace: chebi_ontology
in_subset: 2 STAR
imported from: chebi.owl

2-aminoethyl hydrogen sulfate
type: Class
subclass of: EC 2.6.1.19 (4-aminobutyrate--2-oxoglutarate transaminase) inhibitor
charge: 0
monoisotopicmass: 141.00958
mass: 141.140
smiles: C(COS(O)(=O)=O)N
formula: C2H7NO4S
database_cross_reference: CAS:926-39-6
id: CHEBI:232350
inchi: InChI=1S/C2H7NO4S/c3-1-2-7-8(4,5)6/h1-3H2,(H,4,5,6)
database_cross_reference: PMID:31313987
inchikey: WSYUEVRAMDSJKL-UHFFFAOYSA-N
has_obo_namespace: chebi_ontology
has_related_synonym: ethanolamine O-sulfate
in_subset: 2 STAR
imported from: chebi.owl

(2-hept-2-ynylsulfanylphenyl) acetate
type: Class
subclass of: non-steroidal anti-inflammatory drug
charge: 0
monoisotopicmass: 262.10275
mass: 262.370
formula: C15H18O2S
database_cross_reference: CAS:209125-28-0
smiles: CCCCC#CCSC1=CC=CC=C1OC(C)=O
id: CHEBI:232352
inchikey: GXMBHQRROXQUJS-UHFFFAOYSA-N
inchi: InChI=1S/C15H18O2S/c1-3-4-5-6-9-12-18-15-11-8-7-10-14(15)17-13(2)16/h7-8,10-11H,3-5,12H2,1-2H3
database_cross_reference: PMID:26305987
has_obo_namespace: chebi_ontology
in_subset: 2 STAR
imported from: chebi.owl

meperfluthrin
type: Class
subclass of: pyrethroid insecticide
charge: 0
monoisotopicmass: 414.04126
mass: 415.210
formula: C17H16Cl2F4O3
database_cross_reference: CAS:915288-13-0
id: CHEBI:232355
inchikey: MWFQAAWRPDRKDG-KOLCDFICSA-N
has_obo_namespace: chebi_ontology
in_subset: 2 STAR
imported from: chebi.owl

ML309
type: Class
subclass of: EC 1.1.1.42 (isocitrate dehydrogenase) inhibitor
charge: 0
has_exact_synonym: 2-(N-[2-(benzimidazol-1-yl)acetyl]-3-fluoroanilino)-N-cyclopentyl-2-(2-methylphenyl)acetamide
monoisotopicmass: 484.22745
mass: 484.575
formula: C29H29FN4O2
id: CHEBI:232356
inchikey: GZLNOSRHZLTDMT-UHFFFAOYSA-N
inchi: InChI=1S/C29H29FN4O2/c1-20-9-2-5-14-24(20)28(29(36)32-22-11-3-4-12-22)34(23-13-8-10-21(30)17-23)27(35)18-33-19-31-25-15-6-7-16-26(25)33/h2,5-10,13-17,19,22,28H,3-4,11-12,18H2,1H3,(H,32,36)
database_cross_reference: PMID:32200800
has_obo_namespace: chebi_ontology
in_subset: 2 STAR
imported from: chebi.owl

tetrahydroindazole
type: Class
subclass of: EC 2.3.1.20 (diacylglycerol O-acyltransferase) inhibitor
charge: 0
monoisotopicmass: 534.87720
mass: 538.000
formula: C17H10BrCl4N5O2
database_cross_reference: CAS:92332-99-5
id: CHEBI:232367
database_cross_reference: HMDB:HMDB0258900
inchikey: ONILAONOGQYBHW-UHFFFAOYSA-N
database_cross_reference: PMID:27428418
has_obo_namespace: chebi_ontology
in_subset: 2 STAR
imported from: chebi.owl

3,4,5-tri-O-galloylquinic acid
type: Class
subclass of: DNA polymerase inhibitor
charge: 0
monoisotopicmass: 648.09626
mass: 648.482
formula: C28H24O18
database_cross_reference: CAS:99745-62-7
id: CHEBI:232370
inchi: InChI=1S/C28H24O18/c29-12-1-9(2-13(30)20(12)35)24(38)44-18-7-28(43,27(41)42)8-19(45-25(39)10-3-14(31)21(36)15(32)4-10)23(18)46-26(40)11-5-16(33)22(37)17(34)6-11/h1-6,18-19,23,29-37,43H,7-8H2,(H,41,42)/t18-,19-,23?,28?/m1/s1
inchikey: PEOHIPMSHPWYAQ-IOALSNHGSA-N
database_cross_reference: PMID:29406740
database_cross_reference: Wikipedia:https://en.wikipedia.org/wiki/3,4,5-Tri-O-galloylquinic_acid
has_obo_namespace: chebi_ontology
in_subset: 2 STAR
imported from: chebi.owl

SAR-AD81
type: Class
subclass of: protein kinase inhibitor
charge: 0
monoisotopicmass: 651.26144
mass: 651.780
formula: C34H41N3O8S
id: CHEBI:232374
inchi: InChI=1S/C34H41N3O8S/c1-23(2)20-36(46(42,43)29-16-14-28(44-4)15-17-29)21-31(39)30(18-13-25-9-6-5-7-10-25)35-33(40)32-22-37(34(41)45-32)27-12-8-11-26(19-27)24(3)38/h5-12,14-17,19,23,30-32,39H,13,18,20-22H2,1-4H3,(H,35,40)/t30-,31+,32-/m0/s1
inchikey: NWOVALISMAROAW-QAXCHELISA-N
database_cross_reference: PMID:27626672
has_obo_namespace: chebi_ontology
in_subset: 2 STAR
imported from: chebi.owl

3-aminopropyl(methyl)phosphinic acid
type: Class
subclass of: GABA agonist
charge: 0
monoisotopicmass: 137.06057
mass: 137.119
has_related_synonym: 3-APMPA
formula: C4H12NO2P
database_cross_reference: CAS:127729-35-5
id: CHEBI:232376
smiles: CP(CCCN)(O)=O
inchi: InChI=1S/C4H12NO2P/c1-8(6,7)4-2-3-5/h2-5H2,1H3,(H,6,7)
inchikey: NHVRIDDXGZPJTJ-UHFFFAOYSA-N
has_related_synonym: SKF-97541
has_obo_namespace: chebi_ontology
in_subset: 2 STAR
imported from: chebi.owl

CGP-54626
type: Class
subclass of: GABA antagonist
charge: 0
monoisotopicmass: 407.11839
mass: 408.300
formula: C18H28Cl2NO3P
id: CHEBI:232377
inchikey: JGGVBBYJRQOPPA-BBRMVZONSA-N
has_obo_namespace: chebi_ontology
has_exact_synonym: cyclohexylmethyl-[(2S)-3-[[(1S)-1-(3,4-dichlorophenyl)ethyl]amino]-2-hydroxypropyl]phosphinic acid
in_subset: 2 STAR
imported from: chebi.owl

triflumezopyrim
type: Class
subclass of: insecticide
charge: 0
monoisotopicmass: 398.09906
mass: 398.345
formula: C20H13F3N4O2
database_cross_reference: CAS:1263133-33-0
id: CHEBI:232379
inchi: InChI=1S/C20H13F3N4O2/c21-20(22,23)15-5-3-4-14(8-15)17-18(28)26-7-2-1-6-16(26)27(19(17)29)11-13-9-24-12-25-10-13/h1-10,12H,11H2
inchikey: LHZOTJOOBRODLL-UHFFFAOYSA-N
database_cross_reference: PMID:27130855
has_obo_namespace: chebi_ontology
in_subset: 2 STAR
imported from: chebi.owl

GNE-3511
type: Class
subclass of: inhibitor
charge: 0
has_exact_synonym: 2-[[6-(3,3-difluoropyrrolidin-1-yl)-4-[1-(oxetan-3-yl)piperidin-4-yl]pyridin-2-yl]amino]pyridine-4-carbonitrile
monoisotopicmass: 440.21362
mass: 440.499
formula: C23H26F2N6O
id: CHEBI:232381
inchi: InChI=1S/C23H26F2N6O/c24-23(25)4-8-31(15-23)22-11-18(17-2-6-30(7-3-17)19-13-32-14-19)10-21(29-22)28-20-9-16(12-26)1-5-27-20/h1,5,9-11,17,19H,2-4,6-8,13-15H2,(H,27,28,29)
database_cross_reference: PMID:25341110
inchikey: RHFIAUKMKYHHFA-UHFFFAOYSA-N
has_obo_namespace: chebi_ontology
in_subset: 2 STAR
imported from: chebi.owl

BIX-01294 trihydrochloride
type: Class
subclass of: EC 2.1.1.* (methyltransferases) inhibitor
charge: 0
monoisotopicmass: 598.23566
mass: 600.030
has_related_synonym: BIX 01294 trihydrochloride
formula: C28H38N6O2.ClH.ClH.ClH
database_cross_reference: CAS:1392399-03-9
id: CHEBI:232399
smiles: CN1CCCN(CC1)C2=NC3=CC(=C(C=C3/C(=N/C4CCN(CC4)CC5=CC=CC=C5)/N2)OC)OC.Cl.Cl.Cl
inchikey: FMURUEPQXKJIPS-UHFFFAOYSA-N
inchi: InChI=1S/C28H38N6O2.3ClH/c1-32-12-7-13-34(17-16-32)28-30-24-19-26(36-3)25(35-2)18-23(24)27(31-28)29-22-10-14-33(15-11-22)20-21-8-5-4-6-9-21;;;/h4-6,8-9,18-19,22H,7,10-17,20H2,1-3H3,(H,29,30,31);3*1H
has_obo_namespace: chebi_ontology
in_subset: 2 STAR
imported from: chebi.owl

chromophore
type: Class
subclass of: photochemical role
id: CHEBI:23240
definition: The part (atom or group of atoms) of a molecular entity in which the electronic transition responsible for a given spectral band is approximately localized.
database_cross_reference: Wikipedia:Chromophore
has_obo_namespace: chebi_ontology
has_exact_synonym: chromophore
has_related_synonym: chromophores
in_subset: 3 STAR
imported from: chebi.owl

N-methyl-4-phenylpyridinium iodide
type: Class
subclass of: mitochondrial NADH:ubiquinone reductase inhibitor
charge: 0
monoisotopicmass: 297.00144
mass: 297.139
formula: C12H12N.I
database_cross_reference: CAS:36913-39-0
id: CHEBI:232401
smiles: C[N+]1=CC=C(C=C1)C2=CC=CC=C2.[I-]
inchi: InChI=1S/C12H12N.HI/c1-13-9-7-12(8-10-13)11-5-3-2-4-6-11;/h2-10H,1H3;1H/q+1;/p-1
database_cross_reference: PMID:20483372
inchikey: RFDFRDXIIKROAI-UHFFFAOYSA-M
has_obo_namespace: chebi_ontology
in_subset: 2 STAR
imported from: chebi.owl

eeyarestatin I
type: Class
subclass of: inhibitor
charge: 0
monoisotopicmass: 629.11925
mass: 630.440
formula: C27H25Cl2N7O7
database_cross_reference: CAS:412960-54-4
id: CHEBI:232402
inchikey: JTUXTPWYZXWOIB-LWWHHIEBSA-N
database_cross_reference: PMID:20865169
has_obo_namespace: chebi_ontology
has_related_synonym: eeyarestatin 1
in_subset: 2 STAR
imported from: chebi.owl

ammonium tetrathiomolybdate
type: Class
subclass of: copper chelator
charge: 0
mass: 262.288
monoisotopicmass: 263.87809
database_cross_reference: CAS:15060-55-6
id: CHEBI:232403
formula: H10MoN2S4
inchi: InChI=1S/Mo.2H3N.2H2S.2S/h;2*1H3;2*1H2;;
database_cross_reference: PMID:18775584
inchikey: ZKKLPDLKUGTPME-UHFFFAOYSA-N
smiles: [Mo].N.N.S.S.[S].[S]
has_obo_namespace: chebi_ontology
in_subset: 2 STAR
imported from: chebi.owl

haedoxan
type: Class
subclass of: pesticide
charge: 0
monoisotopicmass: 654.19486
mass: 654.621
formula: C33H34O14
database_cross_reference: CAS:123619-26-1
id: CHEBI:232406
inchi: InChI=1S/C33H34O14/c1-35-12-26-27(16-5-6-19-21(7-16)42-14-41-19)46-23-9-20(36-2)17(8-22(23)45-26)28-18-11-39-32(33(18,34)13-40-28)47-30-24(37-3)10-25-29(31(30)38-4)44-15-43-25/h5-10,18,26-28,32,34H,11-15H2,1-4H3/t18-,26-,27-,28-,32-,33-/m1/s1
inchikey: SVQIUEXUTJVJTM-KTIWSMOXSA-N
has_obo_namespace: chebi_ontology
has_related_synonym: haedoxan A
in_subset: 2 STAR
imported from: chebi.owl

racemetirosine
type: Class
subclass of: EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitor
charge: 0
monoisotopicmass: 195.08954
mass: 195.218
formula: C10H13NO3
database_cross_reference: CAS:658-48-0
smiles: CC(CC1=CC=C(C=C1)O)(C(=O)O)N
id: CHEBI:232408
database_cross_reference: HMDB:HMDB0247174
inchi: InChI=1S/C10H13NO3/c1-10(11,9(13)14)6-7-2-4-8(12)5-3-7/h2-5,12H,6,11H2,1H3,(H,13,14)
inchikey: NHTGHBARYWONDQ-UHFFFAOYSA-N
database_cross_reference: PMID:28900300
has_related_synonym: alpha-methyl-p-tyrosine
has_obo_namespace: chebi_ontology
in_subset: 2 STAR
imported from: chebi.owl

WAY-100635 maleate
type: Class
subclass of: serotonergic antagonist
charge: 0
monoisotopicmass: 538.27913
mass: 538.645
formula: C25H34N4O2.C4H4O4
id: CHEBI:232409
inchi: InChI=1S/C25H34N4O2.C4H4O4/c1-31-23-12-6-5-11-22(23)28-18-15-27(16-19-28)17-20-29(24-13-7-8-14-26-24)25(30)21-9-3-2-4-10-21;5-3(6)1-2-4(7)8/h5-8,11-14,21H,2-4,9-10,15-20H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1+
database_cross_reference: PMID:21818550
has_related_synonym: WAY100635
inchikey: XIGAHNVCEFUYOV-WLHGVMLRSA-N
has_obo_namespace: chebi_ontology
in_subset: 2 STAR
imported from: chebi.owl

EHT 1864
type: Class
subclass of: EC 3.6.5.* (hydrolases acting on GTP; involved in cellular and subcellular movement) inhibitor
charge: 0
has_exact_synonym: 2-(morpholin-4-ylmethyl)-5-[5-[7-(trifluoromethyl)quinolin-4-yl]sulfanylpentoxy]pyran-4-one;dihydrochloride
has_related_synonym: 5-(5-(7-(Trifluoromethyl)quinolin-4-ylthio)pentyloxy)-2-(morpholinomethyl)-4H-pyran-4-one dihydrochloride
monoisotopicmass: 580.11772
mass: 581.470
formula: C25H27F3N2O4S.ClH.ClH
database_cross_reference: CAS:754240-09-0
id: CHEBI:232411
inchikey: LSECOAJFCKFQJG-UHFFFAOYSA-N
database_cross_reference: PMID:35976098
has_obo_namespace: chebi_ontology
in_subset: 2 STAR
imported from: chebi.owl

VU041
type: Class
subclass of: potassium channel blocker
charge: 0
monoisotopicmass: 363.15585
mass: 363.384
formula: C19H20F3N3O
id: CHEBI:232413
inchikey: DLAGRCZUELSZFG-UHFFFAOYSA-N
inchi: InChI=1S/C19H20F3N3O/c20-19(21,22)18-14-8-2-4-10-16(14)25(23-18)12-17(26)24-11-5-7-13-6-1-3-9-15(13)24/h1,3,6,9H,2,4-5,7-8,10-12H2
database_cross_reference: PMID:29371678
has_obo_namespace: chebi_ontology
in_subset: 2 STAR
imported from: chebi.owl

EGTA acetoxymethyl ester
type: Class
subclass of: chelator
charge: 0
monoisotopicmass: 668.22761
mass: 668.602
formula: C26H40N2O18
database_cross_reference: CAS:99590-86-0
id: CHEBI:232417
has_related_synonym: EGTA-AM
inchikey: GNJXVFXIDHCCKR-UHFFFAOYSA-N
inchi: InChI=1S/C26H40N2O18/c1-19(29)39-15-43-23(33)11-27(12-24(34)44-16-40-20(2)30)5-7-37-9-10-38-8-6-28(13-25(35)45-17-41-21(3)31)14-26(36)46-18-42-22(4)32/h5-18H2,1-4H3
database_cross_reference: PMID:30102150
has_obo_namespace: chebi_ontology
in_subset: 2 STAR
imported from: chebi.owl

dexpramipexole
type: Class
subclass of: dopamine agonist
charge: 0
monoisotopicmass: 211.11432
mass: 211.330
formula: C10H17N3S
database_cross_reference: CAS:104632-28-2
smiles: CCCN[C@@]1(CCC2=C(C1)SC(=N)N2)[H]
id: CHEBI:232420
inchikey: FASDKYOPVNHBLU-SSDOTTSWSA-N
inchi: InChI=1S/C10H17N3S/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8/h7,12H,2-6H2,1H3,(H2,11,13)/t7-/m1/s1
database_cross_reference: KEGG:D09886
database_cross_reference: Wikipedia:https://en.wikipedia.org/wiki/Dexpramipexole
has_obo_namespace: chebi_ontology
in_subset: 2 STAR
imported from: chebi.owl

MitoTEMPO
type: Class
subclass of: radical scavenger
charge: 0
monoisotopicmass: 509.21247
mass: 510.028
formula: C29H35ClN2O2P
smiles: CC1(C)CC(CC(C)(C)N1[O])\N=C(\C[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)/[O-].Cl
id: CHEBI:232424
inchi: InChI=1S/C29H34N2O2P.ClH/c1-28(2)20-23(21-29(3,4)31(28)33)30-27(32)22-34(24-14-8-5-9-15-24,25-16-10-6-11-17-25)26-18-12-7-13-19-26;/h5-19,23H,20-22H2,1-4H3;1H
has_related_synonym: Mito-TEMPO
database_cross_reference: PMID:29213118
inchikey: WKKFJIJNGHNQQW-UHFFFAOYSA-N
has_obo_namespace: chebi_ontology
in_subset: 2 STAR
imported from: chebi.owl

calcium chelator
type: Class
subclass of: chelator
definition: A chelator that is any compound containing a ligand (typically organic) which is able to form a bond to a central calcium atom at two or more points.
id: CHEBI:232436
has_related_synonym: calcium chelating agent
has_related_synonym: calcium chelating agents
has_related_synonym: calcium chelators
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

p53 inhibitor
type: Class
subclass of: inhibitor
definition: Any inhibitor of tumour protein p53.
id: CHEBI:232442
database_cross_reference: PMID:31310659
database_cross_reference: Wikipedia:P53
has_related_synonym: cellular tumor antigen p53 inhibitor
has_related_synonym: cellular tumor antigen p53 inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: p53 inhibitors
has_related_synonym: phosphoprotein p53 inhibitor
has_related_synonym: phosphoprotein p53 inhibitors
has_related_synonym: tumor protein p53 inhibitor
has_related_synonym: tumor protein p53 inhibitors
has_related_synonym: tumour protein p53 inhibitor
has_related_synonym: tumour protein p53 inhibitors
has_related_synonym: tumour suppressor p53 inhibitor
has_related_synonym: tumour suppressor p53 inhibitors
in_subset: 3 STAR
imported from: chebi.owl

mass spectrometer degradation product
type: Class
subclass of: chemical role
charge: 0
mass: 0.000
monoisotopicmass: 0.00000
definition: Any product obtained as a result of mass spectrometer degradation.
id: CHEBI:232530
has_obo_namespace: chebi_ontology
in_subset: 2 STAR
imported from: chebi.owl

saredutant
type: Class
subclass of: antagonist
charge: 0
monoisotopicmass: 551.21063
mass: 552.536
formula: C31H35Cl2N3O2
database_cross_reference: CAS:142001-63-6
id: CHEBI:233291
database_cross_reference: DrugBank:DB06660
has_exact_synonym: N-[(2S)-4-(4-acetamido-4-phenylpiperidin-1-yl)-2-(3,4-dichlorophenyl)butyl]-N-methylbenzamide
inchikey: PGKXDIMONUAMFR-AREMUKBSSA-N
database_cross_reference: PMID:38057665
has_related_synonym: SR 48968
database_cross_reference: Wikipedia:https://en.wikipedia.org/wiki/Saredutant
has_obo_namespace: chebi_ontology
in_subset: 2 STAR
imported from: chebi.owl

AK-1
type: Class
subclass of: EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor
charge: 0
has_exact_synonym: 3-(azepan-1-ylsulfonyl)-N-(3-nitrophenyl)benzamide
monoisotopicmass: 403.1201917719999
mass: 403.46000000000004
formula: C19H21N3O5S
id: CHEBI:233328
inchikey: HAYBKCHPEBZNGW-UHFFFAOYSA-N
inchi: InChI=1S/C19H21N3O5S/c23-19(20-16-8-6-9-17(14-16)22(24)25)15-7-5-10-18(13-15)28(26,27)21-11-3-1-2-4-12-21/h5-10,13-14H,1-4,11-12H2,(H,20,23)
database_cross_reference: PMID:20378838
has_obo_namespace: chebi_ontology
in_subset: 2 STAR
imported from: chebi.owl

P2Y14 receptor antagonist
type: Class
subclass of: G-protein-coupled receptor antagonist
definition: An antagonist at the P2Y14 receptor.
has_related_synonym: BPR105 anatgonist
has_related_synonym: BPR105 antagonists
id: CHEBI:233336
has_related_synonym: G protein-coupled receptor 105 antagonist
has_related_synonym: G protein-coupled receptor 105 antagonists
has_related_synonym: GPR105 antagonist
has_related_synonym: GPR105 antagonists
has_related_synonym: KIAA0001 antagonist
has_related_synonym: KIAA0001 antagonists
has_related_synonym: P2RY14 antagonist
has_related_synonym: P2RY14 antagonists
has_related_synonym: P2Y purinoceptor 14 antagonist
has_related_synonym: P2Y purinoceptor 14 antagonists
has_related_synonym: P2Y14 antagonist
has_related_synonym: P2Y14 antagonists
has_related_synonym: P2Y14 receptor antagonists
has_related_synonym: P2Y14R antagonist
has_related_synonym: P2Y14R antagonists
database_cross_reference: Wikipedia:P2RY14
has_obo_namespace: chebi_ontology
has_related_synonym: purinergic receptor P2Y14 antagonist
has_related_synonym: purinergic receptor P2Y14 antagonists
in_subset: 3 STAR
imported from: chebi.owl

EC 1.14.11.68 ([histone H3]-trimethyl-L-lysine(27) demethylase) inhibitor
type: Class
subclass of: EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor
definition: An EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor that interferes with the action of [histone H3]-trimethyl-L-lysine(27) demethylase (EC 1.14.11.68).
id: CHEBI:233404
has_related_synonym: EC 1.14.11.68 ([histone H3]-trimethyl-L-lysine(27) demethylase) inhibitors
has_related_synonym: EC 1.14.11.68 inhibitor
has_related_synonym: EC 1.14.11.68 inhibitors
has_related_synonym: JMJD3 inhibitor
has_related_synonym: JMJD3 inhibitors
has_related_synonym: KDM6A inhibitor
has_related_synonym: KDM6A inhibitors
has_related_synonym: KDM6C inhibitor
has_related_synonym: KDM6C inhibitors
has_related_synonym: UTX inhibitor
has_related_synonym: UTX inhibitors
has_related_synonym: UTY inhibitor
has_related_synonym: UTY inhibitors
has_related_synonym: [histone H3]-N(6),N(6),N(6)-trimethyl-L-lysine-27,2-oxoglutarate:oxygen oxidoreductase inhibitor
has_related_synonym: [histone H3]-N(6),N(6),N(6)-trimethyl-L-lysine-27,2-oxoglutarate:oxygen oxidoreductase inhibitors
has_related_synonym: [histone H3]-trimethyl-L-lysine(27) demethylase inhibitor
has_related_synonym: [histone H3]-trimethyl-L-lysine(27) demethylase inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

antifibrotic agent
type: Class
subclass of: drug
definition: Any agent which acts to reduce fibrosis.
id: CHEBI:233423
database_cross_reference: Wikipedia:Fibrosis
has_related_synonym: anti-fibrotic agent
has_related_synonym: anti-fibrotic agents
has_related_synonym: antifibrosis agent
has_related_synonym: antifibrosis agents
has_related_synonym: antifibrotic agents
has_related_synonym: antifibrotic drug
has_related_synonym: antifibrotic drugs
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

chemosensitiser
type: Class
subclass of: biological role
definition: Any compound that can sensitise tumour cells to chemotherapy.
id: CHEBI:233442
database_cross_reference: Wikipedia:Chemosensitizer
has_obo_namespace: chebi_ontology
has_related_synonym: chemosensitisers
has_related_synonym: chemosensitising agent
has_related_synonym: chemosensitising agents
has_related_synonym: chemosensitizer
has_related_synonym: chemosensitizers
has_related_synonym: chemosensitizing agent
has_related_synonym: chemosensitizing agents
in_subset: 3 STAR
imported from: chebi.owl

coenzyme
type: Class
subclass of: cofactor
definition: A low-molecular-weight, non-protein organic compound participating in enzymatic reactions as dissociable acceptor or donor of chemical groups or electrons.
id: CHEBI:23354
has_obo_namespace: chebi_ontology
has_exact_synonym: coenzyme
has_related_synonym: coenzymes
in_subset: 3 STAR
imported from: chebi.owl

cofactor
type: Class
subclass of: biochemical role
definition: An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group).
id: CHEBI:23357
database_cross_reference: Wikipedia:Cofactor_(biochemistry)
has_obo_namespace: chebi_ontology
has_exact_synonym: cofactor
has_exact_synonym: cofactors
in_subset: 3 STAR
imported from: chebi.owl

asoxime chloride
type: Class
subclass of: cholinesterase reactivator
charge: 0
has_exact_synonym: 1-[[2-(hydroxyiminomethyl)pyridin-1-ium-1-yl]methoxymethyl]pyridin-1-ium-4-carboxamide;dichloride
monoisotopicmass: 358.05995
mass: 359.213
formula: C14H14N4O3.HCl.HCl
database_cross_reference: CAS:34433-31-3
id: CHEBI:233581
smiles: Cl.Cl.O=NC=C1C=CC=CN1COC[N+]2=CC=C(C=C2)C(=O)[NH-]
has_related_synonym: HI-6
inchi: InChI=1S/C14H14N4O3.2ClH/c15-14(19)12-4-7-17(8-5-12)10-21-11-18-6-2-1-3-13(18)9-16-20;;/h1-9H,10-11H2,(H-,15,19);2*1H/b13-9+;;
database_cross_reference: PMID:39292449
inchikey: QELSIJXWEROXOE-IGUOPLJTSA-N
database_cross_reference: Wikipedia:https://en.wikipedia.org/wiki/Asoxime_chloride
has_obo_namespace: chebi_ontology
in_subset: 2 STAR
imported from: chebi.owl

compatible osmolytes
type: Class
subclass of: osmolyte
id: CHEBI:23366
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

molecular entity
type: Class
subclass of: BAO_0003116
definition: Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity.
id: CHEBI:23367
has_obo_namespace: chebi_ontology
has_related_synonym: entidad molecular
has_related_synonym: entidades moleculares
has_related_synonym: entite moleculaire
has_related_synonym: molecular entities
has_exact_synonym: molecular entity
has_related_synonym: molekulare Entitaet
in_subset: 3 STAR
imported from: chebi.owl

5a,20a-tetrahydroprogesterone
type: Class
subclass of: biological role
charge: 0
has_exact_synonym: 1-(1-hydroxyethyl)-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-7-one
has_related_synonym: 1-(1-hydroxyethyl)-9a,11a-dimethyl-tetradecahydrocyclopenta[a]phenanthren-7-one
monoisotopicmass: 318.25588
mass: 318.501
formula: C21H34O2
id: CHEBI:233713
inchikey: DYVGYXXLXQESJE-UHFFFAOYSA-N
inchi: InChI=1S/C21H34O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h13-14,16-19,22H,4-12H2,1-3H3
database_cross_reference: PMID:2292213
has_obo_namespace: chebi_ontology
in_subset: 2 STAR
imported from: chebi.owl

17a-hydroxy-5a-pregnane-3,20-dione
type: Class
subclass of: biological role
charge: 0
has_related_synonym: 1-acetyl-1-hydroxy-9a,11a-dimethyl-dodecahydro-2H-cyclopenta[a]phenanthren-7-one
has_exact_synonym: 1-acetyl-1-hydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-7-one
monoisotopicmass: 332.23514
mass: 332.484
formula: C21H32O3
id: CHEBI:233714
inchi: InChI=1S/C21H32O3/c1-13(22)21(24)11-8-18-16-5-4-14-12-15(23)6-9-19(14,2)17(16)7-10-20(18,21)3/h14,16-18,24H,4-12H2,1-3H3
database_cross_reference: PMID:2292213
inchikey: UUOHXXXJRQGPLC-UHFFFAOYSA-N
has_obo_namespace: chebi_ontology
in_subset: 2 STAR
imported from: chebi.owl

EC 3.2.1.169 (protein O-GlcNAcase) inhibitor
type: Class
subclass of: EC 3.2.1.* (glycosidase) inhibitor
definition: An EC 3.2.1.* (glycosidase) inhibitor that interferes with the action of protein O-GlcNAcase (EC 3.2.1.169).
has_related_synonym: BtGH84 inhibitor
has_related_synonym: BtGH84 inhibitors
id: CHEBI:234036
has_related_synonym: EC 3.2.1.169 (protein O-GlcNAcase) inhibitors
has_related_synonym: EC 3.2.1.169 inhibitor
has_related_synonym: EC 3.2.1.169 inhibitors
has_related_synonym: O-GlcNAc hydrolase inhibitor
has_related_synonym: O-GlcNAc hydrolase inhibitors
has_related_synonym: O-GlcNAcase inhibitor
has_related_synonym: O-GlcNAcase inhibitors
has_related_synonym: OGA inhibitor
has_related_synonym: OGA inhibitors
database_cross_reference: Wikipedia:Protein_O-GlcNAcase
has_related_synonym: [protein]-3-O-(N-acetyl-beta-D-glucosaminyl)-L-serine/threonine N-acetylglucosaminyl hydrolase inhibitor
has_related_synonym: [protein]-3-O-(N-acetyl-beta-D-glucosaminyl)-L-serine/threonine N-acetylglucosaminyl hydrolase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: glycoside hydrolase O-GlcNAcase inhibitor
has_related_synonym: glycoside hydrolase O-GlcNAcase inhibitors
has_related_synonym: protein O-GlcNAcase inhibitor
has_related_synonym: protein O-GlcNAcase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

OLIG2 inhibitor
type: Class
subclass of: inhibitor
definition: Any inhibitor of OLIG2.
has_related_synonym: BHLHB1 inhibitor
has_related_synonym: BHLHB1 inhibitors
id: CHEBI:234089
has_related_synonym: OLIG2 inhibitors
has_related_synonym: OLIGO2 inhibitor
has_related_synonym: OLIGO2 inhibitors
has_related_synonym: PRKCBP2 inhibitor
has_related_synonym: PRKCBP2 inhibitors
has_related_synonym: RACK17 inhibitor
has_related_synonym: RACK17 inhibitors
database_cross_reference: Wikipedia:OLIG2
has_related_synonym: bHLHe19 inhibitor
has_related_synonym: bHLHe19 inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: oligodendrocyte lineage transcription factor 2 inhibitor
has_related_synonym: oligodendrocyte lineage transcription factor 2 inhibitors
has_related_synonym: oligodendrocyte transcription factor 2 inhibitor
has_related_synonym: oligodendrocyte transcription factor 2 inhibitors
has_related_synonym: oligodendrocyte transcription factor inhibitor
has_related_synonym: oligodendrocyte transcription factor inhibitors
in_subset: 3 STAR
imported from: chebi.owl

Double stranded DNA
type: Class
subclass of: biological role
id: CHEBI:234102
definition: Double-stranded DNA from Xenopus laevis
database_cross_reference: PMID:12079350
has_obo_namespace: chebi_ontology
in_subset: 2 STAR
imported from: chebi.owl

cytochrome-b6f complex inhibitor
type: Class
subclass of: photosynthetic electron-transport chain inhibitor
id: CHEBI:23529
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

cytokinin
type: Class
subclass of: plant hormone
definition: A phytohormone that promote cell division, or cytokinesis, in plant roots and shoots.
id: CHEBI:23530
database_cross_reference: Wikipedia:Cytokinin
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

defoliant
type: Class
subclass of: herbicide
definition: A herbicide which when sprayed or dusted on plants causes its leaves to fall off.
id: CHEBI:23582
has_related_synonym: Defoliationsmittel
has_related_synonym: Entlaubungsmittel
has_obo_namespace: chebi_ontology
has_related_synonym: defoliants
in_subset: 3 STAR
imported from: chebi.owl

drug
type: Class
subclass of: pharmaceutical
definition: Any substance which when absorbed into a living organism may modify one or more of its functions. The term is generally accepted for a substance taken for a therapeutic purpose, but is also commonly used for abused substances.
id: CHEBI:23888
has_obo_namespace: chebi_ontology
has_related_synonym: drugs
has_related_synonym: medicine
in_subset: 3 STAR
imported from: chebi.owl

ecdysone antagonists
type: Class
subclass of: insect growth regulator
id: CHEBI:23891
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

enzyme inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
definition: A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
id: CHEBI:23924
has_obo_namespace: chebi_ontology
has_exact_synonym: enzyme inhibitor
has_related_synonym: enzyme inhibitors
has_related_synonym: inhibidor enzimatico
has_related_synonym: inhibidores enzimaticos
has_related_synonym: inhibiteur enzymatique
has_related_synonym: inhibiteurs enzymatiques
in_subset: 3 STAR
imported from: chebi.owl

estradiol
type: Class
subclass of: molecular entity
charge: 0
monoisotopicmass: 272.17763
mass: 272.38196
definition: A 3-hydroxy steroid that is estra-1,3,5(10)-triene substituted by hydroxy groups at positions 3 and 17.
formula: C18H24O2
id: CHEBI:23965
has_alternative_id: CHEBI:42364
inchi: InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17?,18+/m1/s1
database_cross_reference: PMID:10696569
database_cross_reference: PMID:24084694
inchikey: VOXZDWNPVJITMN-WKUFJEKOSA-N
database_cross_reference: Wikipedia:Estradiol
has_obo_namespace: chebi_ontology
has_exact_synonym: estra-1,3,5(10)-triene-3,17-diol
has_related_synonym: oestradiol
in_subset: 3 STAR
imported from: chebi.owl

ethylene releasers
type: Class
subclass of: plant growth regulator
id: CHEBI:24002
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

fat-soluble vitamin (role)
type: Class
subclass of: vitamin (role)
definition: Any vitamin that dissolves in fats and are stored in body tissues. Unlike the water-soluble vitamins, they are stored in the body for long periods of time and generally pose a greater risk for toxicity when consumed in excess.
id: CHEBI:24020
database_cross_reference: PMID:31838543
database_cross_reference: PMID:32057251
database_cross_reference: PMID:33549284
database_cross_reference: PMID:34045883
has_obo_namespace: chebi_ontology
has_related_synonym: fat-soluble vitamin
has_related_synonym: fat-soluble vitamins
has_related_synonym: fettloesliche Vitamine
in_subset: 3 STAR
imported from: chebi.owl

iron(3+) chelator
type: Class
subclass of: iron chelator
id: CHEBI:24028
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

fungicide
type: Class
subclass of: pesticide
subclass of: antifungal agent
definition: A substance used to destroy fungal pests.
id: CHEBI:24127
has_obo_namespace: chebi_ontology
has_related_synonym: fungicides
in_subset: 3 STAR
imported from: chebi.owl

EC 6.3.1.2 (glutamate--ammonia ligase) inhibitor
type: Class
subclass of: EC 6.3.1.* (acid-ammonia/amine ligase) inhibitor
definition: An EC 6.3.* (C-N bond-forming ligase) inhibitor that interferes with the action of glutamate--ammonia ligase (EC 6.3.1.2).
id: CHEBI:24319
has_related_synonym: EC 6.3.1.2 (glutamate--ammonia ligase) inhibitors
has_related_synonym: EC 6.3.1.2 inhibitor
has_related_synonym: EC 6.3.1.2 inhibitors
has_related_synonym: L-glutamate:ammonia ligase (ADP-forming) inhibitor
has_related_synonym: L-glutamate:ammonia ligase (ADP-forming) inhibitors
has_related_synonym: L-glutamine synthetase inhibitor
has_related_synonym: L-glutamine synthetase inhibitors
database_cross_reference: Wikipedia:Glutamine_synthetase
has_obo_namespace: chebi_ontology
has_related_synonym: glutamate--ammonia ligase (EC 6.3.1.2) inhibitor
has_related_synonym: glutamate--ammonia ligase (EC 6.3.1.2) inhibitors
has_related_synonym: glutamate--ammonia ligase inhibitor
has_related_synonym: glutamate--ammonia ligase inhibitors
has_related_synonym: glutamine synthetase inhibitor
has_related_synonym: glutamine synthetase inhibitors
has_related_synonym: glutamylhydroxamic synthetase inhibitor
has_related_synonym: glutamylhydroxamic synthetase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

group transfer coenzymes
type: Class
subclass of: coenzyme
id: CHEBI:24430
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

biological role
type: Class
subclass of: BAO_0002929
definition: A role played by the molecular entity or part thereof within a biological context.
id: CHEBI:24432
has_related_synonym: biological function
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

herbicide
type: Class
subclass of: pesticide
definition: A substance used to destroy plant pests.
id: CHEBI:24527
has_related_synonym: Herbizid
has_related_synonym: Unkrautbekaempfungsmittel
has_related_synonym: Unkrautvertilgungsmittel
database_cross_reference: Wikipedia:Herbicide
has_related_synonym: Wildkrautbekaempfungsmittel
has_obo_namespace: chebi_ontology
has_related_synonym: herbicides
in_subset: 3 STAR
imported from: chebi.owl

hormone
type: Class
subclass of: molecular messenger
subclass of: agonist
id: CHEBI:24621
definition: Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds.
has_obo_namespace: chebi_ontology
has_related_synonym: endocrine
has_related_synonym: hormones
in_subset: 3 STAR
imported from: chebi.owl

insect attractant
type: Class
subclass of: biological role
definition: A chemical that attracts insects.
id: CHEBI:24850
database_cross_reference: PMID:7044287
has_obo_namespace: chebi_ontology
has_related_synonym: insect attractants
in_subset: 3 STAR
imported from: chebi.owl

insect growth regulator
type: Class
subclass of: insecticide
subclass of: growth regulator
definition: A growth regulator that inhibits the life cycle of an insect.
id: CHEBI:24851
has_obo_namespace: chebi_ontology
has_related_synonym: insect growth regulators
in_subset: 3 STAR
imported from: chebi.owl

insecticide
type: Class
subclass of: pesticide
id: CHEBI:24852
definition: Strictly, a substance intended to kill members of the class Insecta. In common usage, any substance used for preventing, destroying, repelling or controlling insects.
database_cross_reference: Wikipedia:Insecticide
has_obo_namespace: chebi_ontology
has_related_synonym: insecticides
in_subset: 3 STAR
imported from: chebi.owl

intercalator
type: Class
subclass of: mutagen
definition: A role played by a chemical agent which exhibits the capability of occupying space between DNA base pairs due to particular properties in size, shape and charge. Intercalation of chemical compounds in DNA helix can result in replication errors (shift, mutation) or DNA damages.
id: CHEBI:24853
has_related_synonym: agente intercalante
has_obo_namespace: chebi_ontology
has_related_synonym: intercalating agent
has_related_synonym: intercalating agents
has_related_synonym: intercalating ligands
has_related_synonym: intercalators
in_subset: 3 STAR
imported from: chebi.owl

ionophore
type: Class
subclass of: membrane transport modulator
definition: A compound which can carry specific ions through membranes of cells or organelles.
id: CHEBI:24869
database_cross_reference: Wikipedia:Ionophore
has_obo_namespace: chebi_ontology
has_exact_synonym: ionophore
has_related_synonym: ionophores
in_subset: 3 STAR
imported from: chebi.owl

iron ionophore
type: Class
subclass of: ionophore
definition: Any ionophore capable of transportation of iron ions across membranes.
id: CHEBI:24874
has_obo_namespace: chebi_ontology
has_related_synonym: iron ionophores
in_subset: 3 STAR
imported from: chebi.owl

jasmonates
type: Class
subclass of: plant hormone
id: CHEBI:24937
definition: The jasmonates (JAs) are a group of plant hormones which help regulate plant growth and development.
database_cross_reference: Wikipedia:Jasmonate
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

juvenile hormone antagonists
type: Class
subclass of: insect growth regulator
id: CHEBI:24941
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

juvenile hormone mimic
type: Class
subclass of: insect growth regulator
id: CHEBI:24942
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

luciferin
type: Class
subclass of: photobiochemical role
definition: A low-molecular-mass compound present in bioluminescent organisms that emits light when oxidized in presence of enzyme luciferase.
id: CHEBI:25078
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

metabolite
type: Class
subclass of: biochemical role
definition: Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
id: CHEBI:25212
has_alternative_id: CHEBI:26619
has_alternative_id: CHEBI:35220
has_obo_namespace: chebi_ontology
has_exact_synonym: metabolite
has_related_synonym: metabolites
has_related_synonym: primary metabolites
has_related_synonym: secondary metabolites
in_subset: 3 STAR
imported from: chebi.owl

mitochondrial respiratory-chain inhibitor
type: Class
subclass of: respiratory-chain inhibitor
id: CHEBI:25355
has_obo_namespace: chebi_ontology
has_related_synonym: mitochondrial electron transport chain inhibitors
has_related_synonym: mitochondrial electron-transport chain inhibitor
has_related_synonym: mitochondrial respiratory chain inhibitors
in_subset: 3 STAR
imported from: chebi.owl

mutagen
type: Class
subclass of: genotoxin
definition: An agent that increases the frequency of mutations above the normal background level, usually by interacting directly with DNA and causing it damage, including base substitution.
id: CHEBI:25435
database_cross_reference: Wikipedia:Mutagen
has_obo_namespace: chebi_ontology
has_related_synonym: mutagene
has_related_synonym: mutagenes
has_related_synonym: mutagenic agent
has_related_synonym: mutageno
has_related_synonym: mutagenos
has_related_synonym: mutagens
in_subset: 3 STAR
imported from: chebi.owl

mycotoxin
type: Class
subclass of: toxin
subclass of: fungal metabolite
id: CHEBI:25442
definition: Poisonous substance produced by fungi.
has_obo_namespace: chebi_ontology
has_related_synonym: fungal toxins
has_related_synonym: mycotoxins
in_subset: 3 STAR
imported from: chebi.owl

nematicide
type: Class
subclass of: pesticide
definition: A substance used to destroy pests of the phylum Nematoda (roundworms).
id: CHEBI:25491
database_cross_reference: Wikipedia:Nematicide
has_obo_namespace: chebi_ontology
has_related_synonym: nematicides
has_related_synonym: nematocide
has_related_synonym: nematocides
in_subset: 3 STAR
imported from: chebi.owl

neurotransmitter
type: Class
subclass of: molecular messenger
definition: An endogenous compound that is used to transmit information across the synapse between a neuron and another cell.
id: CHEBI:25512
database_cross_reference: Wikipedia:Neurotransmitter
has_obo_namespace: chebi_ontology
has_related_synonym: neurotransmitters
in_subset: 3 STAR
imported from: chebi.owl

neonicotinoid insectide
type: Class
subclass of: insecticide
subclass of: nicotinic acetylcholine receptor agonist
subclass of: neurotoxin
definition: A class of neuro-active insecticides that act at the nicotinic acetylcholine receptor.
has_alternative_id: CHEBI:25498
id: CHEBI:25540
database_cross_reference: Wikipedia:Neonicotinoid
has_obo_namespace: chebi_ontology
has_related_synonym: neonicotinoid insectides
has_related_synonym: nicotinoid insectide
has_related_synonym: nicotinoid insectides
in_subset: 3 STAR
imported from: chebi.owl

nodulation factor
type: Class
subclass of: biological role
definition: A role played by signal molecules produced by the symbiotic bacteria that trigger nodule formation (typically on the host plant roots).
id: CHEBI:25573
has_related_synonym: NF
has_obo_namespace: chebi_ontology
has_related_synonym: nod factor
has_related_synonym: nodulation factors
in_subset: 3 STAR
imported from: chebi.owl

nucleoside antibiotic
type: Class
subclass of: antimicrobial agent
id: CHEBI:25605
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

osmolyte
type: Class
subclass of: biological role
definition: A solute used by a cell under water stress to maintain cell volume.
id: CHEBI:25728
has_obo_namespace: chebi_ontology
has_related_synonym: osmolytes
in_subset: 3 STAR
imported from: chebi.owl

oxidized luciferins
type: Class
subclass of: luciferin
id: CHEBI:25747
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

pesticide synergist
type: Class
subclass of: pesticide
definition: A substance that increases the efficacy of a pesticide.
id: CHEBI:25943
has_obo_namespace: chebi_ontology
has_related_synonym: pesticide synergists
in_subset: 3 STAR
imported from: chebi.owl

pesticide
type: Class
subclass of: application
id: CHEBI:25944
has_related_synonym: Pestizid
has_related_synonym: Pestizide
definition: Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests.
database_cross_reference: Wikipedia:Pesticide
has_obo_namespace: chebi_ontology
has_exact_synonym: pesticide
has_related_synonym: pesticides
in_subset: 3 STAR
imported from: chebi.owl

pheromone
type: Class
subclass of: semiochemical
definition: A semiochemical used in olfactory communication between organisms of the same species eliciting a change in sexual or social behaviour.
id: CHEBI:26013
database_cross_reference: PMID:23988175
database_cross_reference: Wikipedia:Pheromone
has_obo_namespace: chebi_ontology
has_related_synonym: ectohormone
has_related_synonym: feromone
has_exact_synonym: pheromone
has_related_synonym: pheromones
in_subset: 3 STAR
imported from: chebi.owl

phosphorus containing antibiotics
type: Class
subclass of: aliphatic antibiotics
id: CHEBI:26083
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

photosynthetic electron-transport chain inhibitor
type: Class
subclass of: herbicide
subclass of: electron-transport chain inhibitor
id: CHEBI:26087
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

photosystem-I inhibitor
type: Class
subclass of: photosynthetic electron-transport chain inhibitor
id: CHEBI:26088
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

photosystem-II inhibitor
type: Class
subclass of: photosynthetic electron-transport chain inhibitor
id: CHEBI:26089
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

phytoalexin
type: Class
subclass of: phytotoxin
definition: A toxin made by a plant that acts against an organism attacking it.
id: CHEBI:26115
has_obo_namespace: chebi_ontology
has_related_synonym: phytoalexins
in_subset: 3 STAR
imported from: chebi.owl

biological pigment
type: Class
subclass of: biophysical role
definition: An endogenous molecular entity that results in a colour of an organism as the consequence of the selective absorption of light.
id: CHEBI:26130
has_obo_namespace: chebi_ontology
has_related_synonym: pigments
in_subset: 3 STAR
imported from: chebi.owl

plant growth regulator
type: Class
subclass of: growth regulator
definition: A chemical, natural or artificial, that can affect the rate of growth of a plant.
id: CHEBI:26155
has_obo_namespace: chebi_ontology
has_related_synonym: plant growth regulators
in_subset: 3 STAR
imported from: chebi.owl

plant growth stimulator
type: Class
subclass of: plant growth regulator
id: CHEBI:26157
has_obo_namespace: chebi_ontology
has_related_synonym: plant growth stimulators
in_subset: 3 STAR
imported from: chebi.owl

precocenes
type: Class
subclass of: juvenile hormone antagonists
id: CHEBI:26220
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

prosthetic group
type: Class
subclass of: cofactor
definition: A tightly bound, specific nonpolypeptide unit in a protein determining and involved in its biological activity.
id: CHEBI:26348
has_obo_namespace: chebi_ontology
has_related_synonym: groupe prosthetique
has_exact_synonym: prosthetic group
has_related_synonym: prosthetic groups
in_subset: 3 STAR
imported from: chebi.owl

pyrethroid insecticide
type: Class
subclass of: insecticide
subclass of: sodium channel modulator
id: CHEBI:26413
has_obo_namespace: chebi_ontology
has_related_synonym: pyrethroid insecticides
in_subset: 3 STAR
imported from: chebi.owl

semiochemical
type: Class
subclass of: molecular messenger
definition: A molecular messenger released by an organism that affects the behaviour within or between species.
id: CHEBI:26645
database_cross_reference: Wikipedia:Semiochemical
has_obo_namespace: chebi_ontology
has_related_synonym: semiochemicals
in_subset: 3 STAR
imported from: chebi.owl

sideramine
type: Class
subclass of: siderophore
id: CHEBI:26671
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

siderophore
type: Class
subclass of: cofactor
subclass of: iron(3+) chelator
subclass of: iron ionophore
definition: Any of low-molecular-mass iron(III)-chelating compounds produced by microorganisms for the purpose of the transport and sequestration of iron.
id: CHEBI:26672
has_obo_namespace: chebi_ontology
has_related_synonym: ferrioxamine
has_related_synonym: ferrioxamines
has_related_synonym: ironophore
has_related_synonym: siderochrome
has_related_synonym: siderochromes
has_exact_synonym: siderophore
has_related_synonym: siderophores
in_subset: 3 STAR
imported from: chebi.owl

amodiaquine
type: Class
subclass of: molecular entity
charge: 0
monoisotopicmass: 355.14514
mass: 355.86100
has_exact_synonym: 4-[(7-chloroquinolin-4-yl)amino]-2-[(diethylamino)methyl]phenol
definition: A quinoline having a chloro group at the 7-position and an aryl amino group at the 4-position.
has_exact_synonym: Amodiaquine
formula: C20H22ClN3O
database_cross_reference: CAS:86-42-0
smiles: CCN(CC)Cc1cc(Nc2ccnc3cc(Cl)ccc23)ccc1O
id: CHEBI:2674
database_cross_reference: DrugBank:DB00613
database_cross_reference: Drug_Central:186
inchi: InChI=1S/C20H22ClN3O/c1-3-24(4-2)13-14-11-16(6-8-20(14)25)23-18-9-10-22-19-12-15(21)5-7-17(18)19/h5-12,25H,3-4,13H2,1-2H3,(H,22,23)
database_cross_reference: KEGG:C07626
database_cross_reference: KEGG:D02922
database_cross_reference: LINCS:LSM-4042
inchikey: OVCDSSHSILBFBN-UHFFFAOYSA-N
database_cross_reference: PDBeChem:CQA
database_cross_reference: PMID:11044276
database_cross_reference: PMID:11971651
database_cross_reference: PMID:17046445
database_cross_reference: PMID:17222819
database_cross_reference: PMID:18419816
database_cross_reference: PMID:18855526
database_cross_reference: PMID:19024339
database_cross_reference: PMID:19245687
database_cross_reference: PMID:26206402
database_cross_reference: PMID:26597254
database_cross_reference: PMID:26647924
database_cross_reference: PMID:26735991
database_cross_reference: PMID:26851641
database_cross_reference: PMID:26900802
database_cross_reference: PMID:26930583
database_cross_reference: PMID:27031231
database_cross_reference: PMID:8885219
database_cross_reference: Patent:US2474821
database_cross_reference: Reaxys:300962
database_cross_reference: Wikipedia:Amodiaquine
has_related_synonym: amodiaquina
has_related_synonym: amodiaquine
has_related_synonym: amodiaquinum
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

synthetic auxin
type: Class
subclass of: auxin
subclass of: xenobiotic
definition: A synthetic compound exhibiting auxin activity.
id: CHEBI:26841
has_obo_namespace: chebi_ontology
has_related_synonym: synthetic auxins
in_subset: 3 STAR
imported from: chebi.owl

systemic acquired resistance inducing compounds
type: Class
subclass of: xenobiotic
id: CHEBI:26842
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

toxin
type: Class
subclass of: metabolite
subclass of: poison
id: CHEBI:27026
definition: Poisonous substance produced by a biological organism such as a microbe, animal or plant.
database_cross_reference: Wikipedia:Toxin
has_obo_namespace: chebi_ontology
has_exact_synonym: toxin
has_related_synonym: toxins
in_subset: 3 STAR
imported from: chebi.owl

micronutrient
type: Class
subclass of: nutrient
definition: Any nutrient required in small quantities by organisms throughout their life in order to orchestrate a range of physiological functions.
id: CHEBI:27027
database_cross_reference: Wikipedia:Micronutrient
has_obo_namespace: chebi_ontology
has_related_synonym: micronutrients
has_related_synonym: trace elements
in_subset: 3 STAR
imported from: chebi.owl

volatile oil component
type: Class
subclass of: biochemical role
subclass of: plant metabolite
definition: Any plant metabolite that is found naturally as a component of a volatile oil.
id: CHEBI:27311
database_cross_reference: Wikipedia:Essential_oil
has_obo_namespace: chebi_ontology
has_related_synonym: essential oil component
has_related_synonym: essential oil components
has_related_synonym: ethereal oil component
has_related_synonym: ethereal oil components
has_related_synonym: volatile oil components
in_subset: 3 STAR
imported from: chebi.owl

water-soluble vitamin (role)
type: Class
subclass of: vitamin (role)
definition: Any vitamin that dissolves in water and readily absorbed into tissues for immediate use. Unlike the fat-soluble vitamins, they are not stored in the body and need to be replenished regularly in the diet and will rarely accumulate to toxic levels since they are quickly excreted from the body via urine.
id: CHEBI:27314
has_obo_namespace: chebi_ontology
has_related_synonym: wasserloesliche Vitamine
has_related_synonym: water-soluble vitamin
has_related_synonym: water-soluble vitamins
in_subset: 3 STAR
imported from: chebi.owl

xenobiotic organic ethers
type: Class
subclass of: xenobiotic
id: CHEBI:27334
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

detergent
type: Class
subclass of: application
subclass of: surfactant
definition: A surfactant (or a mixture containing one or more surfactants) having cleaning properties in dilute solutions.
has_alternative_id: CHEBI:23648
id: CHEBI:27780
has_alternative_id: CHEBI:4456
has_related_synonym: Detergents
database_cross_reference: KEGG:C01689
has_obo_namespace: chebi_ontology
has_exact_synonym: detergent
in_subset: 3 STAR
imported from: chebi.owl

quinidine
type: Class
subclass of: molecular entity
has_related_synonym: (+)-Quinidine
has_related_synonym: (+)-quinidine
has_related_synonym: (8R,9S)-quinidine
has_exact_synonym: (9S)-6'-methoxycinchonan-9-ol
has_related_synonym: (R)-(6-methoxyquinolin-4-yl)((3S,4R,7S)-3-vinylquinuclidin-7-yl)methanol
has_related_synonym: (S)-(6-Methoxy-quinolin-4-yl)-((2R,5R)-5-vinyl-1-aza-bicyclo[2.2.2]oct-2-yl)-methanol
has_related_synonym: (S)-(6-methoxyquinolin-4-yl)((2R,5R)-5-vinylquinuclidin-2-yl)methanol
charge: 0
monoisotopicmass: 324.18378
mass: 324.41680
has_related_synonym: 6-methoxy-alpha-(5-vinyl-2-quinuclidinyl)-4-quinolinemethanol
definition: A cinchona alkaloid consisting of cinchonine with the hydrogen at the 6-position of the quinoline ring substituted by methoxy.
formula: C20H24N2O2
database_cross_reference: CAS:56-54-2
has_alternative_id: CHEBI:127150
has_alternative_id: CHEBI:26494
id: CHEBI:28593
has_alternative_id: CHEBI:355477
has_alternative_id: CHEBI:529982
has_alternative_id: CHEBI:595841
has_alternative_id: CHEBI:597286
has_alternative_id: CHEBI:604323
has_alternative_id: CHEBI:8719
has_related_synonym: CIN-QUIN
has_related_synonym: Chinidin
has_related_synonym: Conchinin
database_cross_reference: DrugBank:DB00908
database_cross_reference: Drug_Central:2346
inchi: InChI=1S/C20H24N2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3/t13-,14-,19+,20-/m0/s1
database_cross_reference: KEGG:C06527
database_cross_reference: KEGG:D08458
has_related_synonym: Kinidin
database_cross_reference: LINCS:LSM-3325
inchikey: LOUPRKONTZGTKE-LHHVKLHASA-N
database_cross_reference: PMID:12477351
database_cross_reference: PMID:12699389
database_cross_reference: PMID:14971904
database_cross_reference: PMID:14973303
database_cross_reference: PMID:15089813
database_cross_reference: PMID:15225721
database_cross_reference: PMID:15270556
database_cross_reference: PMID:15328252
database_cross_reference: PMID:16570918
database_cross_reference: PMID:17132069
database_cross_reference: PMID:17228875
database_cross_reference: PMID:17249648
database_cross_reference: PMID:17870541
database_cross_reference: PMID:18324762
database_cross_reference: PMID:18395298
database_cross_reference: PMID:18788725
database_cross_reference: PMID:23861085
database_cross_reference: PMID:24130427
database_cross_reference: PMID:445303
database_cross_reference: PMID:8337232
database_cross_reference: PMID:9864343
has_exact_synonym: Quinidine
database_cross_reference: Reaxys:91866
has_related_synonym: alpha-(6-methoxy-4-quinolyl)-5-vinyl-2-quinuclidinemethanol
has_related_synonym: beta-quinine
has_obo_namespace: chebi_ontology
has_related_synonym: chinidinum
has_related_synonym: conquinine
has_related_synonym: pitayine
has_related_synonym: quinidina
has_exact_synonym: quinidine
in_subset: 3 STAR
imported from: chebi.owl

bupropion
type: Class
subclass of: molecular entity
charge: 0
has_exact_synonym: 2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one
monoisotopicmass: 239.10769
mass: 239.74086
definition: An aromatic ketone that is propiophenone carrying a tert-butylamino group at position 2 and a chloro substituent at position 3 on the phenyl ring.
has_exact_synonym: Bupropion
formula: C13H18ClNO
database_cross_reference: CAS:34841-39-9
database_cross_reference: CAS:34911-55-2
smiles: CC(NC(C)(C)C)C(=O)c1cccc(Cl)c1
id: CHEBI:3219
database_cross_reference: DrugBank:DB01156
database_cross_reference: Drug_Central:435
database_cross_reference: HMDB:HMDB0001510
inchi: InChI=1S/C13H18ClNO/c1-9(15-13(2,3)4)12(16)10-6-5-7-11(14)8-10/h5-9,15H,1-4H3
database_cross_reference: KEGG:C06860
database_cross_reference: KEGG:D07591
database_cross_reference: LINCS:LSM-1267
database_cross_reference: MetaCyc:CPD-3481
database_cross_reference: PMID:12826985
database_cross_reference: PMID:15876900
database_cross_reference: Reaxys:2101062
inchikey: SNPPWIUOZRMYNY-UHFFFAOYSA-N
database_cross_reference: Wikipedia:Bupropion
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

vitamin (role)
type: Class
subclass of: micronutrient
subclass of: biochemical role
definition: A biochemical role played by any micronutrient that is an organic compound. Vitamins are present in foods in small amounts and are essential to normal metabolism and biochemical functions, usually as coenzymes. The term "vitamines" (from vita + amines) was coined in 1912 by Casimir Funk, who believed that these compounds were amines.
has_alternative_id: CHEBI:10004
has_alternative_id: CHEBI:27305
id: CHEBI:33229
database_cross_reference: Wikipedia:Vitamin
has_obo_namespace: chebi_ontology
has_related_synonym: vitamin
has_related_synonym: vitamina
has_related_synonym: vitaminas
has_related_synonym: vitamine
has_related_synonym: vitamines
has_related_synonym: vitamins
has_related_synonym: vitaminum
in_subset: 3 STAR
imported from: chebi.owl

antitubercular agent
type: Class
subclass of: antimycobacterial drug
definition: A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis.
id: CHEBI:33231
has_related_synonym: antitubercular
has_related_synonym: antitubercular agents
has_related_synonym: antitubercular drug
has_related_synonym: antitubercular drugs
has_obo_namespace: chebi_ontology
has_related_synonym: tuberculostatic agent
in_subset: 3 STAR
imported from: chebi.owl

application
type: Class
subclass of: BAO_0002929
id: CHEBI:33232
definition: Intended use of the molecular entity or part thereof by humans.
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

molecular messenger
type: Class
subclass of: biological role
id: CHEBI:33280
has_obo_namespace: chebi_ontology
has_related_synonym: chemical messenger
in_subset: 3 STAR
imported from: chebi.owl

antimicrobial agent
type: Class
subclass of: biological role
definition: A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
has_related_synonym: Antibiotika
has_related_synonym: Antibiotikum
has_alternative_id: CHEBI:22582
id: CHEBI:33281
database_cross_reference: PMID:12964249
database_cross_reference: PMID:22117953
database_cross_reference: PMID:22439833
database_cross_reference: PMID:22849268
database_cross_reference: PMID:22849276
database_cross_reference: PMID:22958833
has_related_synonym: antibiotic
has_related_synonym: antibiotics
has_related_synonym: antibiotique
has_related_synonym: antimicrobial
has_related_synonym: antimicrobial agents
has_related_synonym: antimicrobials
has_obo_namespace: chebi_ontology
has_related_synonym: microbicide
has_related_synonym: microbicides
in_subset: 3 STAR
imported from: chebi.owl

antibacterial agent
type: Class
subclass of: antimicrobial agent
definition: A substance (or active part thereof) that kills or slows the growth of bacteria.
id: CHEBI:33282
has_related_synonym: antibacterial agents
has_related_synonym: antibacterials
has_related_synonym: bactericide
has_related_synonym: bactericides
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

nutrient
type: Class
subclass of: food component
definition: A nutrient is a food component that an organism uses to survive and grow.
id: CHEBI:33284
has_obo_namespace: chebi_ontology
has_related_synonym: nutrients
in_subset: 3 STAR
imported from: chebi.owl

agrochemical
type: Class
subclass of: application
definition: An agrochemical is a substance that is used in agriculture or horticulture.
id: CHEBI:33286
database_cross_reference: Wikipedia:Agrochemical
has_related_synonym: agrichemical
has_related_synonym: agrichemicals
has_related_synonym: agricultural chemicals
has_related_synonym: agrochemicals
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

fertilizer
type: Class
subclass of: agrochemical
definition: A fertilizer is any substance that is added to soil or water to assist the growth of plants.
id: CHEBI:33287
has_obo_namespace: chebi_ontology
has_related_synonym: fertiliser
has_related_synonym: fertilizers
in_subset: 3 STAR
imported from: chebi.owl

rodenticide
type: Class
subclass of: pesticide
definition: A substance used to destroy rodent pests.
id: CHEBI:33288
database_cross_reference: Wikipedia:Rodenticide
has_obo_namespace: chebi_ontology
has_related_synonym: rodenticides
in_subset: 3 STAR
imported from: chebi.owl

avicide
type: Class
subclass of: pesticide
definition: A substance used to destroy bird pests (class Aves).
id: CHEBI:33289
database_cross_reference: Wikipedia:Avicide
has_related_synonym: avicides
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

food
type: Class
subclass of: physiological role
definition: A physiological role played by any substance of either plant, animal or artificial origin which contains essential body nutrients that can be ingested by an organism to provide energy, promote growth, and maintain the processes of life.
id: CHEBI:33290
has_obo_namespace: chebi_ontology
has_related_synonym: food material
has_related_synonym: food materials
has_related_synonym: food role
has_related_synonym: foods
has_related_synonym: foodstuff
has_related_synonym: foodstuffs
in_subset: 3 STAR
imported from: chebi.owl

fuel
type: Class
subclass of: application
definition: An energy-rich substance that can be transformed with release of usable energy.
id: CHEBI:33292
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

diagnostic agent
type: Class
subclass of: pharmaceutical
definition: A substance administered to aid diagnosis of a disease.
id: CHEBI:33295
has_obo_namespace: chebi_ontology
has_related_synonym: diagnostic aid
in_subset: 3 STAR
imported from: chebi.owl

reagent
type: Class
subclass of: application
definition: A substance used in a chemical reaction to detect, measure, examine, or produce other substances.
id: CHEBI:33893
has_obo_namespace: chebi_ontology
has_related_synonym: reactif
has_related_synonym: reactivo
has_exact_synonym: reagent
has_related_synonym: reagents
in_subset: 3 STAR
imported from: chebi.owl

molluscicide
type: Class
subclass of: pesticide
definition: A substance used to destroy pests of the phylum Mollusca.
id: CHEBI:33904
database_cross_reference: Wikipedia:Molluscicide
has_obo_namespace: chebi_ontology
has_related_synonym: molluscicides
in_subset: 3 STAR
imported from: chebi.owl

macronutrient
type: Class
subclass of: nutrient
definition: Any nutrient required in large quantities by organisms throughout their life in order to orchestrate a range of physiological functions. Macronutrients are usually chemical elements (carbon, hydrogen, nitrogen, oxygen, phosphorus and sulfur) that humans consume in the largest quantities. Calcium, sodium, magnesium and potassium are sometimes included as macronutrients because they are required in relatively large quantities compared with other vitamins and minerals.
id: CHEBI:33937
has_obo_namespace: chebi_ontology
has_related_synonym: macronutrients
in_subset: 3 STAR
imported from: chebi.owl

surfactant
type: Class
subclass of: emulsifier
definition: A substance which lowers the surface tension of the medium in which it is dissolved, and/or the interfacial tension with other phases, and, accordingly, is positively adsorbed at the liquid/vapour and/or at other interfaces.
id: CHEBI:35195
has_obo_namespace: chebi_ontology
has_related_synonym: surface active agent
has_exact_synonym: surfactant
has_related_synonym: surfactants
in_subset: 3 STAR
imported from: chebi.owl

lumiphore
type: Class
subclass of: photochemical role
definition: A part of a molecular entity (atom or group of atoms) in which electronic excitation associated with a given emission band is approximately localized.
id: CHEBI:35197
has_obo_namespace: chebi_ontology
has_related_synonym: luminophore
has_exact_synonym: lumiphore
in_subset: 3 STAR
imported from: chebi.owl

tracer
type: Class
subclass of: application
definition: A role played by a foreign substance mixed with or attached to a given substance to enable the distribution or location of the latter to be determined subsequently.
id: CHEBI:35204
has_obo_namespace: chebi_ontology
has_exact_synonym: tracer
in_subset: 3 STAR
imported from: chebi.owl

chemical tracer
type: Class
subclass of: tracer
definition: A role played by a chemical compound with properties similar to those of the substance being traced with which it is mixed homogeneously.
id: CHEBI:35205
has_obo_namespace: chebi_ontology
has_exact_synonym: chemical tracer
in_subset: 3 STAR
imported from: chebi.owl

isotopic tracer
type: Class
subclass of: tracer
definition: A tracer which only differs in isotopic composition from the substance to be traced.
id: CHEBI:35206
has_obo_namespace: chebi_ontology
has_exact_synonym: isotopic tracer
in_subset: 3 STAR
imported from: chebi.owl

radioactive tracer
type: Class
subclass of: tracer
definition: A tracer containing a radioactive label.
id: CHEBI:35207
has_obo_namespace: chebi_ontology
has_exact_synonym: radioactive tracer
in_subset: 3 STAR
imported from: chebi.owl

physical tracer
type: Class
subclass of: tracer
definition: A physical tracer is one that is attached by physical means to the object being traced.
id: CHEBI:35208
has_obo_namespace: chebi_ontology
has_exact_synonym: physical tracer
in_subset: 3 STAR
imported from: chebi.owl

label
type: Class
subclass of: application
definition: A role played by a part of a molecular entity distinguishable by the observer but not by the system and used to identify a tracer.
id: CHEBI:35209
has_obo_namespace: chebi_ontology
has_exact_synonym: label
in_subset: 3 STAR
imported from: chebi.owl

spin label
type: Class
subclass of: label
definition: A role played by a stable paramagnetic group that is attached to a part of a molecular entity whose microscopic environment is of interest and may be revealed by the electron spin resonance (ESR) spectroscopy.
id: CHEBI:35210
has_obo_namespace: chebi_ontology
has_exact_synonym: spin label
in_subset: 3 STAR
imported from: chebi.owl

radioactive label
type: Class
subclass of: label
id: CHEBI:35211
has_obo_namespace: chebi_ontology
has_exact_synonym: radioactive label
in_subset: 3 STAR
imported from: chebi.owl

plant growth retardant
type: Class
subclass of: plant growth regulator
has_alternative_id: CHEBI:26154
has_alternative_id: CHEBI:26156
id: CHEBI:35219
has_obo_namespace: chebi_ontology
has_related_synonym: plant growth inhibitor
has_related_synonym: plant growth inhibitors
has_related_synonym: plant growth retardants
in_subset: 3 STAR
imported from: chebi.owl

antimetabolite
type: Class
subclass of: biochemical role
definition: A substance which is structurally similar to a metabolite but which competes with it or replaces it, and so prevents or reduces its normal utilization.
id: CHEBI:35221
database_cross_reference: Wikipedia:Antimetabolite
has_exact_synonym: antimetabolite
has_related_synonym: antimetabolites
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

inhibitor
type: Class
subclass of: biological role
definition: A substance that diminishes the rate of a chemical reaction.
id: CHEBI:35222
has_obo_namespace: chebi_ontology
has_related_synonym: inhibidor
has_related_synonym: inhibiteur
has_exact_synonym: inhibitor
has_related_synonym: inhibitors
in_subset: 3 STAR
imported from: chebi.owl

catalyst
type: Class
subclass of: chemical role
definition: A substance that increases the rate of a reaction without modifying the overall standard Gibbs energy change in the reaction.
id: CHEBI:35223
has_related_synonym: Katalysator
has_related_synonym: catalizador
has_related_synonym: catalyseur
has_exact_synonym: catalyst
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

effector
type: Class
subclass of: biochemical role
definition: A small molecule which increases (activator) or decreases (inhibitor) the activity of an (allosteric) enzyme by binding to the enzyme at the regulatory site (which is different from the substrate-binding catalytic site).
id: CHEBI:35224
database_cross_reference: Wikipedia:Effector_(biology)
has_obo_namespace: chebi_ontology
has_exact_synonym: effector
has_related_synonym: enzyme modulator
in_subset: 3 STAR
imported from: chebi.owl

buffer
type: Class
subclass of: chemical role
definition: Any substance or mixture of substances that, in solution (typically aqueous), resists change in pH upon addition of small amounts of acid or base.
id: CHEBI:35225
has_related_synonym: buffer compound
has_related_synonym: buffer compounds
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

spin probe
type: Class
subclass of: probe
definition: A role played by a stable paramagnetic molecular entity used to study the microscopic environment by electron paramagnetic resonance (EPR) spectroscopy without covalent attachment to the molecular entity of interest.
id: CHEBI:35226
database_cross_reference: Wikipedia:Spin_probe
has_obo_namespace: chebi_ontology
has_exact_synonym: spin probe
in_subset: 3 STAR
imported from: chebi.owl

fossil fuel
type: Class
subclass of: fuel
definition: A fuel such as coal, oil and natural gas which has formed over many years through the decomposition of deposited vegetation which was under extreme pressure of an overburden of earth.
id: CHEBI:35230
has_obo_namespace: chebi_ontology
has_exact_synonym: fossil fuel
in_subset: 3 STAR
imported from: chebi.owl

nuclear fuel
type: Class
subclass of: fuel
id: CHEBI:35231
definition: Material containing fissile nuclides, which when placed in a reactor, enables a chain reaction to be achieved.
has_obo_namespace: chebi_ontology
has_exact_synonym: nuclear fuel
in_subset: 3 STAR
imported from: chebi.owl

radiopharmaceutical
type: Class
subclass of: pharmaceutical
definition: Any pharmaceutical compound containing a radioisotope.
id: CHEBI:35232
database_cross_reference: Wikipedia:Radiopharmaceutical
has_obo_namespace: chebi_ontology
has_related_synonym: radiopharmaceuticals
in_subset: 3 STAR
imported from: chebi.owl

central nervous system stimulant
type: Class
subclass of: central nervous system drug
definition: Any drug that enhances the activity of the central nervous system.
id: CHEBI:35337
has_related_synonym: CNS stimulant
database_cross_reference: Wikipedia:Central_nervous_system_stimulants
has_related_synonym: analeptic
has_related_synonym: analeptic agent
has_related_synonym: analeptic drug
has_related_synonym: analeptics
has_exact_synonym: central nervous system stimulant
has_related_synonym: central stimulant
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

antiinfective agent
type: Class
subclass of: drug
definition: A substance used in the prophylaxis or therapy of infectious diseases.
id: CHEBI:35441
has_related_synonym: anti-infective agents
has_related_synonym: anti-infective drugs
has_related_synonym: antiinfective agents
has_related_synonym: antiinfective drug
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

antiparasitic agent
type: Class
subclass of: antiinfective agent
definition: A substance used to treat or prevent parasitic infections.
id: CHEBI:35442
database_cross_reference: Wikipedia:Antiparasitic
has_related_synonym: antiparasitic drugs
has_related_synonym: antiparasitics
has_obo_namespace: chebi_ontology
has_related_synonym: parasiticides
in_subset: 3 STAR
imported from: chebi.owl

anthelminthic drug
type: Class
subclass of: antiparasitic agent
id: CHEBI:35443
definition: Substance intended to kill parasitic worms (helminths).
has_exact_synonym: anthelminthic
has_related_synonym: anthelminthics
has_related_synonym: anthelmintic
has_related_synonym: anthelmintics
has_related_synonym: antihelminth
has_related_synonym: antihelmintico
has_obo_namespace: chebi_ontology
has_related_synonym: vermifuge
in_subset: 3 STAR
imported from: chebi.owl

antinematodal drug
type: Class
subclass of: nematicide
subclass of: anthelminthic drug
definition: A substance used in the treatment or control of nematode infestations.
id: CHEBI:35444
has_related_synonym: antinematodal agent
has_related_synonym: antinematodal drugs
has_related_synonym: antinematodals
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor
type: Class
subclass of: antihypertensive agent
subclass of: EC 3.4.15.* (peptidyl-dipeptidase) inhibitor
has_related_synonym: ACE inhibitor
has_related_synonym: ACE inhibitors
definition: An EC 3.4.15.* (peptidyl-dipeptidase) inhibitor that interferes with the action of peptidyl-dipeptidase A (EC 3.4.15.1).
id: CHEBI:35457
has_related_synonym: DCP inhibitor
has_related_synonym: DCP inhibitors
has_related_synonym: EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitors
has_related_synonym: EC 3.4.15.1 inhibitor
has_related_synonym: EC 3.4.15.1 inhibitors
has_related_synonym: PDH inhibitor
has_related_synonym: PDH inhibitors
database_cross_reference: Wikipedia:ACE_inhibitor
has_related_synonym: angiotensin I-converting enzyme inhibitor
has_related_synonym: angiotensin I-converting enzyme inhibitors
has_related_synonym: angiotensin-converting enzyme inhibitor
has_related_synonym: angiotensin-converting enzyme inhibitors
has_related_synonym: carboxycathepsin inhibitor
has_related_synonym: carboxycathepsin inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: dipeptidase inhibitor
has_related_synonym: dipeptidase inhibitors
has_related_synonym: dipeptide hydrolase inhibitor
has_related_synonym: dipeptide hydrolase inhibitors
has_related_synonym: dipeptidyl carboxypeptidase I inhibitor
has_related_synonym: dipeptidyl carboxypeptidase I inhibitors
has_related_synonym: dipeptidyl carboxypeptidase inhibitor
has_related_synonym: dipeptidyl carboxypeptidase inhibitors
has_related_synonym: endothelial cell peptidyl dipeptidase inhibitor
has_related_synonym: endothelial cell peptidyl dipeptidase inhibitors
has_related_synonym: kininase II inhibitor
has_related_synonym: kininase II inhibitors
has_related_synonym: peptidase P inhibitor
has_related_synonym: peptidase P inhibitors
has_related_synonym: peptidyl dipeptidase A inhibitor
has_related_synonym: peptidyl dipeptidase A inhibitors
has_related_synonym: peptidyl dipeptidase I inhibitor
has_related_synonym: peptidyl dipeptidase I inhibitors
has_related_synonym: peptidyl dipeptidase-4 inhibitor
has_related_synonym: peptidyl dipeptidase-4 inhibitors
has_related_synonym: peptidyl dipeptide hydrolase inhibitor
has_related_synonym: peptidyl dipeptide hydrolase inhibitors
has_related_synonym: peptidyl-dipeptidase A (EC 3.4.15.1) inhibitor
has_related_synonym: peptidyl-dipeptidase A (EC 3.4.15.1) inhibitors
has_related_synonym: peptidyl-dipeptidase A inhibitor
has_related_synonym: peptidyl-dipeptidase A inhibitors
has_related_synonym: peptidyl-dipeptide hydrolase inhibitor
has_related_synonym: peptidyl-dipeptide hydrolase inhibitors
has_related_synonym: peptidyldipeptide hydrolase inhibitor
has_related_synonym: peptidyldipeptide hydrolase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

antidepressant
type: Class
subclass of: psychotropic drug
definition: Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.
id: CHEBI:35469
has_related_synonym: antidepressant drugs
has_related_synonym: antidepressants
has_obo_namespace: chebi_ontology
has_related_synonym: thymoanaleptics
has_related_synonym: thymoleptic drugs
has_related_synonym: thymoleptics
in_subset: 3 STAR
imported from: chebi.owl

central nervous system drug
type: Class
subclass of: drug
definition: A class of drugs producing both physiological and psychological effects through a variety of mechanisms involving the central nervous system.
id: CHEBI:35470
has_related_synonym: CNS agent
has_related_synonym: CNS drugs
has_related_synonym: central nervous system agents
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

psychotropic drug
type: Class
subclass of: central nervous system drug
definition: A loosely defined grouping of drugs that have effects on psychological function.
id: CHEBI:35471
database_cross_reference: Wikipedia:Psychotropic_drug
has_obo_namespace: chebi_ontology
has_related_synonym: psychoactive agent
has_related_synonym: psychoactive drugs
has_related_synonym: psychopharmaceuticals
has_related_synonym: psychotropic drugs
in_subset: 3 STAR
imported from: chebi.owl

anti-inflammatory drug
type: Class
subclass of: drug
subclass of: anti-inflammatory agent
definition: A substance that reduces or suppresses inflammation.
id: CHEBI:35472
has_related_synonym: anti-inflammatory drugs
has_related_synonym: antiinflammatory agent
has_related_synonym: antiinflammatory drug
has_related_synonym: antiinflammatory drugs
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

tranquilizing drug
type: Class
subclass of: psychotropic drug
subclass of: central nervous system depressant
definition: A traditional grouping of drugs said to have a soothing or calming effect on mood, thought or behaviour.
id: CHEBI:35473
has_related_synonym: ataractics
has_obo_namespace: chebi_ontology
has_related_synonym: tranquilising drug
has_related_synonym: tranquilizing drugs
has_related_synonym: tranquillising agent
has_related_synonym: tranquillizing agents
in_subset: 3 STAR
imported from: chebi.owl

anxiolytic drug
type: Class
subclass of: tranquilizing drug
definition: Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions.
id: CHEBI:35474
has_related_synonym: anti-anxiety agents
has_related_synonym: anti-anxiety drugs
has_related_synonym: anxiolytic agents
has_related_synonym: anxiolytics
has_obo_namespace: chebi_ontology
has_related_synonym: minor tranquilisers
has_related_synonym: minor tranquilizers
has_related_synonym: minor tranquilizing agents
in_subset: 3 STAR
imported from: chebi.owl

non-steroidal anti-inflammatory drug
type: Class
subclass of: anti-inflammatory drug
subclass of: antirheumatic drug
definition: An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
id: CHEBI:35475
has_related_synonym: NSAID
has_related_synonym: NSAIDs
database_cross_reference: Wikipedia:Non-steroidal_anti-inflammatory_drug
has_obo_namespace: chebi_ontology
has_related_synonym: non-steroidal anti-inflammatory agent
has_related_synonym: non-steroidal anti-inflammatory drugs
in_subset: 3 STAR
imported from: chebi.owl

antipsychotic agent
type: Class
subclass of: tranquilizing drug
definition: Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.
id: CHEBI:35476
has_related_synonym: Neuroleptikum
has_related_synonym: antipsychotic agents
has_related_synonym: antipsychotic drug
has_related_synonym: antipsychotic drugs
has_related_synonym: antipsychotics
has_related_synonym: antipsychotiques
has_obo_namespace: chebi_ontology
has_related_synonym: grosser Tranquilizer
has_related_synonym: major tranquilizers
has_related_synonym: major tranquilizing agents
has_related_synonym: neuroleptic
has_related_synonym: neuroleptic agents
has_related_synonym: neuroleptics
has_related_synonym: neuroleptique
has_related_synonym: neuroleptiques
in_subset: 3 STAR
imported from: chebi.owl

antimanic drug
type: Class
subclass of: tranquilizing drug
definition: Antimanic drugs are agents used to treat bipolar disorders or mania associated with other affective disorders.
id: CHEBI:35477
has_related_synonym: antimanic agent
has_related_synonym: antimanic drugs
has_related_synonym: antimanics
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

analgesic
type: Class
subclass of: drug
subclass of: pharmacological role
definition: An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms.
id: CHEBI:35480
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

non-narcotic analgesic
type: Class
subclass of: analgesic
definition: A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
id: CHEBI:35481
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

opioid analgesic
type: Class
subclass of: analgesic
definition: A narcotic or opioid substance, synthetic or semisynthetic agent producing profound analgesia, drowsiness, and changes in mood.
id: CHEBI:35482
has_obo_namespace: chebi_ontology
has_related_synonym: narcotic
has_related_synonym: narcotic analgesic
has_related_synonym: narcotic analgesics
has_related_synonym: narcotics
has_related_synonym: opioid analgesics
in_subset: 3 STAR
imported from: chebi.owl

EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor
type: Class
subclass of: EC 1.2.1.* (oxidoreductase acting on donor aldehyde/oxo group with NAD(+) or NADP(+) as acceptor) inhibitor
definition: An EC 1.2.1.* (oxidoreductase acting on donor aldehyde/oxo group with NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of aldehyde dehydrogenase (NAD(+)), EC 1.2.1.3.
id: CHEBI:35487
has_related_synonym: CoA-independent aldehyde dehydrogenase inhibitor
has_related_synonym: CoA-independent aldehyde dehydrogenase inhibitors
has_related_synonym: EC 1.2.1.3 (aldehyde dehydrogenase (NAD(+))) inhibitor
has_related_synonym: EC 1.2.1.3 (aldehyde dehydrogenase (NAD(+))) inhibitors
has_related_synonym: EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitors
has_related_synonym: EC 1.2.1.3 inhibitor
has_related_synonym: EC 1.2.1.3 inhibitors
has_related_synonym: NAD-aldehyde dehydrogenase inhibitor
has_related_synonym: NAD-aldehyde dehydrogenase inhibitors
has_related_synonym: NAD-dependent 4-hydroxynonenal dehydrogenase inhibitor
has_related_synonym: NAD-dependent 4-hydroxynonenal dehydrogenase inhibitors
has_related_synonym: NAD-dependent aldehyde dehydrogenase inhibitor
has_related_synonym: NAD-dependent aldehyde dehydrogenase inhibitors
has_related_synonym: NAD-linked aldehyde dehydrogenase inhibitor
has_related_synonym: NAD-linked aldehyde dehydrogenase inhibitors
database_cross_reference: Wikipedia:Aldehyde_dehydrogenase
has_related_synonym: aldehyde dehydrogenase (NAD(+)) (EC 1.2.1.3) inhibitor
has_related_synonym: aldehyde dehydrogenase (NAD(+)) (EC 1.2.1.3) inhibitors
has_related_synonym: aldehyde dehydrogenase (NAD(+)) inhibitor
has_related_synonym: aldehyde dehydrogenase (NAD(+)) inhibitors
has_related_synonym: aldehyde dehydrogenase (NAD) inhibitor
has_related_synonym: aldehyde dehydrogenase (NAD) inhibitors
has_related_synonym: aldehyde dehydrogenase inhibitor
has_related_synonym: aldehyde dehydrogenase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: m-methylbenzaldehyde dehydrogenase inhibitor
has_related_synonym: m-methylbenzaldehyde dehydrogenase inhibitors
has_related_synonym: propionaldehyde dehydrogenase inhibitor
has_related_synonym: propionaldehyde dehydrogenase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

central nervous system depressant
type: Class
subclass of: central nervous system drug
definition: A loosely defined group of drugs that tend to reduce the activity of the central nervous system.
id: CHEBI:35488
has_related_synonym: CNS depressants
has_related_synonym: central nervous system depressants
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

antipyretic
type: Class
subclass of: drug
definition: A drug that prevents or reduces fever by lowering the body temperature from a raised state. An antipyretic will not affect the normal body temperature if one does not have fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever.
id: CHEBI:35493
database_cross_reference: Wikipedia:Antipyretic
has_related_synonym: anti-pyretic
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

androgen antagonist
type: Class
subclass of: hormone antagonist
definition: A compound which inhibits or antagonises the biosynthesis or actions of androgens.
id: CHEBI:35497
database_cross_reference: Wikipedia:Antiandrogen
has_related_synonym: antiandrogen
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

diuretic
type: Class
subclass of: drug
definition: An agent that promotes the excretion of urine through its effects on kidney function.
id: CHEBI:35498
has_obo_namespace: chebi_ontology
has_related_synonym: diuretics
in_subset: 3 STAR
imported from: chebi.owl

hallucinogen
type: Class
subclass of: psychotropic drug
id: CHEBI:35499
definition: Drugs capable of inducing illusions, hallucinations, delusions, paranoid ideations and other alterations of mood and thinking.
has_obo_namespace: chebi_ontology
has_related_synonym: hallucinogenic agents
has_related_synonym: hallucinogenic drugs
has_related_synonym: hallucinogens
has_related_synonym: psychedelic agents
has_related_synonym: psychedelics
in_subset: 3 STAR
imported from: chebi.owl

beta-adrenergic agonist
type: Class
subclass of: adrenergic agonist
subclass of: beta-adrenergic drug
definition: An agent that selectively binds to and activates beta-adrenergic receptors.
id: CHEBI:35522
has_related_synonym: beta-adrenergic agonists
has_related_synonym: beta-adrenergic receptor agonist
has_related_synonym: beta-adrenoceptor agonists
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

bronchodilator agent
type: Class
subclass of: drug
definition: An agent that causes an increase in the expansion of a bronchus or bronchial tubes.
id: CHEBI:35523
has_related_synonym: bronchodilator
has_related_synonym: bronchodilator agents
has_related_synonym: broncholytic agent
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

sympathomimetic agent
type: Class
subclass of: adrenergic agent
definition: A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.
id: CHEBI:35524
has_obo_namespace: chebi_ontology
has_related_synonym: sympathomimetic
has_related_synonym: sympathomimetics
in_subset: 3 STAR
imported from: chebi.owl

hypoglycemic agent
type: Class
subclass of: drug
definition: A drug which lowers the blood glucose level.
id: CHEBI:35526
has_related_synonym: anti-hyperglycemic agent
has_related_synonym: anti-hyperglycemic agents
has_related_synonym: antidiabetic
has_related_synonym: antihyperglycemic
has_related_synonym: antihyperglycemic agent
has_related_synonym: antihyperglycemic agents
has_related_synonym: antihyperglycemic drug
has_related_synonym: antihyperglycemic drugs
has_related_synonym: antihyperglycemics
has_obo_namespace: chebi_ontology
has_related_synonym: hypoglycemic agents
has_related_synonym: hypoglycemic drug
has_related_synonym: hypoglycemic drugs
in_subset: 3 STAR
imported from: chebi.owl

beta-adrenergic antagonist
type: Class
subclass of: adrenergic antagonist
subclass of: beta-adrenergic drug
definition: An agent that binds to but does not activate beta-adrenergic receptors thereby blocking the actions of endogenous or exogenous beta-adrenergic agonists. beta-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety.
id: CHEBI:35530
has_related_synonym: beta-adrenergic antagonists
has_related_synonym: beta-adrenergic blocker
has_related_synonym: beta-adrenergic blockers
has_related_synonym: beta-adrenergic receptor blockaders
has_related_synonym: beta-adrenoceptor antagonists
has_related_synonym: beta-blocker
has_related_synonym: beta-blockers
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor
type: Class
subclass of: EC 1.14.99.* (miscellaneous oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor
has_related_synonym: (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate,hydrogen-donor:oxygen oxidoreductase inhibitor
has_related_synonym: (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate,hydrogen-donor:oxygen oxidoreductase inhibitors
has_related_synonym: (PG)H synthase inhibitor
has_related_synonym: (PG)H synthase inhibitors
definition: A compound or agent that combines with cyclooxygenases (EC 1.14.99.1) and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of icosanoids, prostaglandins, and thromboxanes.
id: CHEBI:35544
has_related_synonym: COX inhibitor
has_related_synonym: EC 1.14.99.1 (cyclooxygenase) inhibitor
has_related_synonym: EC 1.14.99.1 (cyclooxygenase) inhibitors
has_related_synonym: EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitors
has_related_synonym: EC 1.14.99.1 inhibitor
has_related_synonym: EC 1.14.99.1 inhibitors
has_related_synonym: PG synthetase inhibitor
has_related_synonym: PG synthetase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: cyclooxygenase (EC 1.14.99.1) inhibitor
has_related_synonym: cyclooxygenase (EC 1.14.99.1) inhibitors
has_related_synonym: cyclooxygenase inhibitor
has_related_synonym: cyclooxygenase inhibitors
has_related_synonym: fatty acid cyclooxygenase inhibitor
has_related_synonym: fatty acid cyclooxygenase inhibitors
has_related_synonym: prostaglandin G/H synthase inhibitor
has_related_synonym: prostaglandin G/H synthase inhibitors
has_related_synonym: prostaglandin endoperoxide synthetase inhibitor
has_related_synonym: prostaglandin endoperoxide synthetase inhibitors
has_related_synonym: prostaglandin synthase inhibitor
has_related_synonym: prostaglandin synthase inhibitors
has_related_synonym: prostaglandin synthetase inhibitor
has_related_synonym: prostaglandin synthetase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

cardiovascular drug
type: Class
subclass of: drug
definition: A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume.
id: CHEBI:35554
has_related_synonym: cardiovascular agent
has_related_synonym: cardiovascular drugs
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

alpha-adrenergic agonist
type: Class
subclass of: adrenergic agonist
subclass of: alpha-adrenergic drug
definition: An agent that selectively binds to and activates alpha-adrenergic receptors.
id: CHEBI:35569
has_related_synonym: alpha-adrenergic agonists
has_related_synonym: alpha-adrenergic receptor agonist
has_related_synonym: alpha-adrenoceptor agonists
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor
type: Class
subclass of: EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor
definition: An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor which interferes with the activity of the enzyme protein tyrosine phosphatases (PTPs), EC 3.1.3.48, involved in the removal of phosphate groups from phosphorylated tyrosine residues on proteins.
id: CHEBI:35608
has_related_synonym: EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitors
has_related_synonym: EC 3.1.3.48 inhibitor
has_related_synonym: EC 3.1.3.48 inhibitors
has_related_synonym: PPT-phosphatase inhibitor
has_related_synonym: PPT-phosphatase inhibitors
has_related_synonym: PTP-phosphatase inhibitor
has_related_synonym: PTP-phosphatase inhibitors
has_related_synonym: PTPase inhibitor
has_related_synonym: PTPase inhibitors
database_cross_reference: Wikipedia:Protein-tyrosine-phosphatase
has_related_synonym: [phosphotyrosine]protein phosphatase inhibitor
has_related_synonym: [phosphotyrosine]protein phosphatase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: phosphoprotein phosphatase (phosphotyrosine) inhibitor
has_related_synonym: phosphoprotein phosphatase (phosphotyrosine) inhibitors
has_related_synonym: phosphotyrosine histone phosphatase inhibitor
has_related_synonym: phosphotyrosine histone phosphatase inhibitors
has_related_synonym: phosphotyrosine phosphatase inhibitor
has_related_synonym: phosphotyrosine phosphatase inhibitors
has_related_synonym: phosphotyrosine protein phosphatase inhibitor
has_related_synonym: phosphotyrosine protein phosphatase inhibitors
has_related_synonym: phosphotyrosylprotein phosphatase inhibitor
has_related_synonym: phosphotyrosylprotein phosphatase inhibitors
has_related_synonym: protein phosphotyrosine phosphatase inhibitor
has_related_synonym: protein phosphotyrosine phosphatase inhibitors
has_related_synonym: protein tyrosine phosphatase inhibitor
has_related_synonym: protein tyrosine phosphatase inhibitors
has_related_synonym: protein-tyrosine-phosphatase (EC 3.1.3.48) inhibitor
has_related_synonym: protein-tyrosine-phosphatase (EC 3.1.3.48) inhibitors
has_related_synonym: protein-tyrosine-phosphatase inhibitor
has_related_synonym: protein-tyrosine-phosphatase inhibitors
has_related_synonym: protein-tyrosine-phosphate phosphohydrolase inhibitor
has_related_synonym: protein-tyrosine-phosphate phosphohydrolase inhibitors
has_related_synonym: tyrosine O-phosphate phosphatase inhibitor
has_related_synonym: tyrosine O-phosphate phosphatase inhibitors
has_related_synonym: tyrosylprotein phosphatase inhibitor
has_related_synonym: tyrosylprotein phosphatase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

antineoplastic agent
type: Class
subclass of: drug
definition: A substance that inhibits or prevents the proliferation of neoplasms.
id: CHEBI:35610
has_related_synonym: anticancer agent
has_related_synonym: anticancer agents
has_related_synonym: antineoplastic
has_related_synonym: antineoplastic agents
has_obo_namespace: chebi_ontology
has_related_synonym: cytostatic
in_subset: 3 STAR
imported from: chebi.owl

flavouring agent
type: Class
subclass of: food additive
definition: A food additive that is used to added improve the taste or odour of a food.
id: CHEBI:35617
has_obo_namespace: chebi_ontology
has_related_synonym: flavoring agent
has_related_synonym: flavoring agents
has_related_synonym: flavour enhancer
has_related_synonym: flavour enhancers
has_related_synonym: flavouring agents
in_subset: 3 STAR
imported from: chebi.owl

vasodilator agent
type: Class
subclass of: cardiovascular drug
definition: A drug used to cause dilation of the blood vessels.
id: CHEBI:35620
has_obo_namespace: chebi_ontology
has_related_synonym: vasodilator
has_related_synonym: vasodilator agents
in_subset: 3 STAR
imported from: chebi.owl

anticonvulsant
type: Class
subclass of: central nervous system depressant
definition: A drug used to prevent seizures or reduce their severity.
has_related_synonym: Antiepileptika
has_related_synonym: Antiepileptikum
has_related_synonym: Antikonvulsiva
has_related_synonym: Antikonvulsivum
id: CHEBI:35623
has_related_synonym: anti-convulsant
has_related_synonym: anti-convulsants
has_related_synonym: anti-convulsive agent
has_related_synonym: anti-convulsive agents
has_related_synonym: anticonvulsants
has_related_synonym: anticonvulsive agent
has_related_synonym: anticonvulsive agents
has_related_synonym: antiepileptic
has_related_synonym: antiepileptics
has_related_synonym: antiepileptique
has_related_synonym: antiepileptiques
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 3.5.2.6 (beta-lactamase) inhibitor
type: Class
subclass of: EC 3.5.2.* (non-peptide cyclic amide C-N hydrolase) inhibitor
definition: An EC 3.5.2.* (non-peptide cyclic amide C-N hydrolase) inhibitor that interferes with the action of beta-lactamase (EC 3.5.2.6).
id: CHEBI:35625
has_related_synonym: EC 3.5.2.6 (beta-lactamase) inhibitors
has_related_synonym: EC 3.5.2.6 inhibitor
has_related_synonym: EC 3.5.2.6 inhibitors
has_related_synonym: ampicillinase inhibitor
has_related_synonym: ampicillinase inhibitors
has_related_synonym: beta-lactam hydrolase inhibitor
has_related_synonym: beta-lactam hydrolase inhibitors
has_related_synonym: beta-lactamase (EC 3.5.2.6) inhibitor
has_related_synonym: beta-lactamase (EC 3.5.2.6) inhibitors
has_related_synonym: beta-lactamase A, B, C inhibitor
has_related_synonym: beta-lactamase A, B, C inhibitors
has_related_synonym: beta-lactamase AME I inhibitor
has_related_synonym: beta-lactamase AME I inhibitors
has_related_synonym: beta-lactamase I-III inhibitor
has_related_synonym: beta-lactamase I-III inhibitors
has_related_synonym: beta-lactamase inhibitor
has_related_synonym: beta-lactamase inhibitors
has_related_synonym: cephalosporin-beta-lactamase inhibitor
has_related_synonym: cephalosporin-beta-lactamase inhibitors
has_related_synonym: cephalosporinase inhibitor
has_related_synonym: cephalosporinase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: exopenicillinase inhibitor
has_related_synonym: exopenicillinase inhibitors
has_related_synonym: neutrapen inhibitor
has_related_synonym: neutrapen inhibitors
has_related_synonym: penicillin amido-beta-lactamhydrolase inhibitor
has_related_synonym: penicillin amido-beta-lactamhydrolase inhibitors
has_related_synonym: penicillin beta-lactamase inhibitor
has_related_synonym: penicillin beta-lactamase inhibitors
has_related_synonym: penicillinase I, II inhibitor
has_related_synonym: penicillinase I, II inhibitors
has_related_synonym: penicillinase inhibitor
has_related_synonym: penicillinase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.17.3.2 (xanthine oxidase) inhibitor
type: Class
subclass of: EC 1.17.3.* (oxidoreductase acting on CH or CH2 with oxygen as acceptor) inhibitor
definition: An EC 1.17.3.* (oxidoreductase acting on CH or CH2 with oxygen as acceptor) inhibitor that interferes with the action of xanthine oxidase (EC 1.17.3.2).
id: CHEBI:35634
has_related_synonym: EC 1.17.3.2 (xanthine oxidase) inhibitors
has_related_synonym: EC 1.17.3.2 inhibitor
has_related_synonym: EC 1.17.3.2 inhibitors
has_related_synonym: Schardinger enzyme inhibitor
has_related_synonym: Schardinger enzyme inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: hypoxanthine oxidase inhibitor
has_related_synonym: hypoxanthine oxidase inhibitors
has_related_synonym: hypoxanthine-xanthine oxidase inhibitor
has_related_synonym: hypoxanthine-xanthine oxidase inhibitors
has_related_synonym: hypoxanthine:oxygen oxidoreductase inhibitor
has_related_synonym: hypoxanthine:oxygen oxidoreductase inhibitors
has_related_synonym: xanthine oxidase (EC 1.17.3.2) inhibitor
has_related_synonym: xanthine oxidase (EC 1.17.3.2) inhibitors
has_related_synonym: xanthine oxidase inhibitor
has_related_synonym: xanthine oxidase inhibitors
has_related_synonym: xanthine oxidoreductase inhibitor
has_related_synonym: xanthine oxidoreductase inhibitors
has_related_synonym: xanthine:O2 oxidoreductase inhibitor
has_related_synonym: xanthine:O2 oxidoreductase inhibitors
has_related_synonym: xanthine:oxygen oxidoreductase inhibitor
has_related_synonym: xanthine:oxygen oxidoreductase inhibitors
has_related_synonym: xanthine:xanthine oxidase inhibitor
has_related_synonym: xanthine:xanthine oxidase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

adrenergic uptake inhibitor
type: Class
subclass of: adrenergic agent
has_related_synonym: ARI
definition: Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin.
id: CHEBI:35640
has_related_synonym: NERI
has_related_synonym: NRI
has_related_synonym: adrenergic reuptake inhibitor
has_related_synonym: adrenergic reuptake inhibitors
has_related_synonym: adrenergic uptake inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: norepinephrine reuptake inhibitor
has_related_synonym: norepinephrine reuptake inhibitors
in_subset: 3 STAR
imported from: chebi.owl

HIV protease inhibitor
type: Class
subclass of: protease inhibitor
subclass of: anti-HIV agent
definition: An inhibitor of HIV protease, an enzyme required for production of proteins needed for viral assembly.
id: CHEBI:35660
has_related_synonym: HIV protease inhibitors
database_cross_reference: Wikipedia:Protease_inhibitor_(pharmacology)
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor
type: Class
subclass of: EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor
definition: Any EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that inhibits HMG-CoA reductases. Hydroxymethylglutaryl-CoA reductase inhibitors have been shown to lower directly cholesterol synthesis. The Enzyme Commission designation is EC 1.1.1.34 for the NADPH-dependent enzyme and EC 1.1.1.88 for an NADH-dependent enzyme.
id: CHEBI:35664
has_related_synonym: HMG-CoA reductase inhibitor
has_related_synonym: HMG-CoA reductase inhibitors
database_cross_reference: PMID:1464741
database_cross_reference: PMID:15531285
database_cross_reference: PMID:20467214
database_cross_reference: Wikipedia:HMG-CoA_reductase
has_obo_namespace: chebi_ontology
has_related_synonym: hydroxymethylglutaryl-CoA reductase inhibitor
has_related_synonym: hydroxymethylglutaryl-CoA reductase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

antihypertensive agent
type: Class
subclass of: cardiovascular drug
definition: Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
id: CHEBI:35674
database_cross_reference: Wikipedia:Antihypertensive_drug
has_related_synonym: antihypertensive
has_related_synonym: antihypertensive agents
has_related_synonym: antihypertensive drug
has_related_synonym: antihypertensive drugs
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

histamine agonist
type: Class
subclass of: histaminergic drug
definition: A drug that binds to and activates histamine receptors. Although they have been suggested for a variety of clinical applications, histamine agonists have so far been more widely used in research than therapeutically.
id: CHEBI:35678
has_obo_namespace: chebi_ontology
has_related_synonym: histamine agonists
in_subset: 3 STAR
imported from: chebi.owl

antilipemic drug
type: Class
subclass of: drug
definition: A substance used to treat hyperlipidemia (an excess of lipids in the blood).
id: CHEBI:35679
database_cross_reference: Wikipedia:Hypolipidemic_agent
has_related_synonym: antihyperlipemic
has_related_synonym: antihyperlipemics
has_related_synonym: antihyperlipidaemic agent
has_related_synonym: antihyperlipidaemic agents
has_related_synonym: antihyperlipidaemic drug
has_related_synonym: antihyperlipidaemic drugs
has_related_synonym: antihyperlipidemic
has_related_synonym: antihyperlipidemic agent
has_related_synonym: antihyperlipidemic agents
has_related_synonym: antihyperlipidemic drug
has_related_synonym: antihyperlipidemic drugs
has_related_synonym: antihyperlipidemics
has_related_synonym: antilipemic
has_related_synonym: antilipemic drugs
has_related_synonym: antilipemics
has_obo_namespace: chebi_ontology
has_related_synonym: hypolipidemic agent
has_related_synonym: hypolipidemic agents
has_related_synonym: lipid-lowering agent
has_related_synonym: lipid-lowering agents
has_related_synonym: lipid-lowering drug
has_related_synonym: lipid-lowering drugs
in_subset: 3 STAR
imported from: chebi.owl

antiplatyhelmintic drug
type: Class
subclass of: anthelminthic drug
definition: An agent used to treat cestode, trematode, or other flatworm infestations in man or animals.
id: CHEBI:35684
has_related_synonym: antiplatyhelmintic agent
has_related_synonym: antiplatyhelmintic drugs
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

xenobiotic
type: Class
subclass of: biological role
definition: A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means.
has_alternative_id: CHEBI:10074
has_alternative_id: CHEBI:27333
id: CHEBI:35703
database_cross_reference: KEGG:C06708
database_cross_reference: Wikipedia:Xenobiotic
has_exact_synonym: Xenobiotic
has_obo_namespace: chebi_ontology
has_exact_synonym: xenobiotic
has_related_synonym: xenobiotic compounds
has_exact_synonym: xenobiotics
in_subset: 3 STAR
imported from: chebi.owl

immunosuppressive agent
type: Class
subclass of: immunomodulator
definition: An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
id: CHEBI:35705
has_obo_namespace: chebi_ontology
has_related_synonym: immunosuppressant
has_related_synonym: immunosuppressive agents
has_related_synonym: inmunosupresor
in_subset: 3 STAR
imported from: chebi.owl

sedative
type: Class
subclass of: central nervous system depressant
definition: A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.
id: CHEBI:35717
has_obo_namespace: chebi_ontology
has_related_synonym: hypnotics
has_related_synonym: hypnotics and sedatives
has_related_synonym: sedative drug
has_related_synonym: sedatives
has_related_synonym: sedatives and hypnotics
in_subset: 3 STAR
imported from: chebi.owl

antifungal agent
type: Class
subclass of: antimicrobial agent
definition: An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.
id: CHEBI:35718
has_related_synonym: antifungal
has_related_synonym: antifungal agents
has_related_synonym: antifungal drug
has_related_synonym: antifungal drugs
has_related_synonym: antifungals
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

leprostatic drug
type: Class
subclass of: antimycobacterial drug
definition: A substance that suppresses Mycobacterium leprae, ameliorates the clinical manifestations of leprosy, and/or reduces the incidence and severity of leprous reactions.
id: CHEBI:35816
has_obo_namespace: chebi_ontology
has_related_synonym: leprostatic
has_related_synonym: leprostatic agent
has_related_synonym: leprostatic drugs
in_subset: 3 STAR
imported from: chebi.owl

coccidiostat
type: Class
subclass of: antiprotozoal drug
definition: An agent useful in the treatment or prevention of coccidiosis in man or animals.
id: CHEBI:35818
has_related_synonym: anticoccidial agent
has_obo_namespace: chebi_ontology
has_related_synonym: coccidiostats
in_subset: 3 STAR
imported from: chebi.owl

antiprotozoal drug
type: Class
subclass of: antiparasitic agent
subclass of: antimicrobial drug
definition: Any antimicrobial drug which is used to treat or prevent protozoal infections.
id: CHEBI:35820
database_cross_reference: Wikipedia:Antiprotozoal_agent
has_related_synonym: antiprotozoal agent
has_related_synonym: antiprotozoal agents
has_related_synonym: antiprotozoal drugs
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

anticholesteremic drug
type: Class
subclass of: antilipemic drug
definition: A substance used to lower plasma cholesterol levels.
id: CHEBI:35821
has_alternative_id: CHEBI:64906
has_related_synonym: anticholesteremic
has_related_synonym: anticholesteremic agent
has_related_synonym: anticholesteremic drugs
has_related_synonym: antihypercholesterolemic
has_related_synonym: antihypercholesterolemic agent
has_related_synonym: antihypercholesterolemic agents
has_related_synonym: antihypercholesterolemic drug
has_related_synonym: antihypercholesterolemic drugs
has_related_synonym: antihypercholesterolemics
has_obo_namespace: chebi_ontology
has_related_synonym: cholesterol inhibitor
has_related_synonym: cholesterol-lowering agent
has_related_synonym: cholesterol-lowering agents
has_related_synonym: cholesterol-lowering drug
has_related_synonym: cholesterol-lowering drugs
has_related_synonym: hypocholesteremic agent
in_subset: 3 STAR
imported from: chebi.owl

uricosuric drug
type: Class
subclass of: gout suppressant
subclass of: renal agent
definition: A gout suppressant that acts directly on the renal tubule to increase the excretion of uric acid, thus reducing its concentrations in plasma.
id: CHEBI:35841
has_obo_namespace: chebi_ontology
has_related_synonym: uricosuric agent
has_related_synonym: uricosuric drugs
in_subset: 3 STAR
imported from: chebi.owl

antirheumatic drug
type: Class
subclass of: drug
definition: A drug used to treat rheumatoid arthritis.
id: CHEBI:35842
has_related_synonym: anti-rheumatic drugs
has_related_synonym: antirheumatic agent
has_related_synonym: antirheumatic drugs
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

gout suppressant
type: Class
subclass of: antirheumatic drug
definition: A drug that increases uric acid excretion by the kidney (uricosuric drug), decreases uric acid production (antihyperuricemic), or alleviates the pain and inflammation of acute attacks of gout.
id: CHEBI:35845
has_obo_namespace: chebi_ontology
has_related_synonym: gout suppressants
in_subset: 3 STAR
imported from: chebi.owl

renal agent
type: Class
subclass of: drug
definition: A drug used for its effect on the kidneys' regulation of body fluid composition and volume.
id: CHEBI:35846
has_obo_namespace: chebi_ontology
has_related_synonym: renal agents
in_subset: 3 STAR
imported from: chebi.owl

lipoxygenase inhibitor
type: Class
subclass of: EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitor
definition: A compound or agent that combines with lipoxygenase and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of the icosanoid products hydroxyicosatetraenoic acid and various leukotrienes.
id: CHEBI:35856
has_obo_namespace: chebi_ontology
has_related_synonym: lipooxygenase inhibitor
has_related_synonym: lipoxygenase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

serotonergic agonist
type: Class
subclass of: serotonergic drug
has_related_synonym: 5-HT agonist
has_related_synonym: 5-hydroxytryptamine agonist
definition: An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders.
id: CHEBI:35941
has_obo_namespace: chebi_ontology
has_related_synonym: serotonergic agonists
has_related_synonym: serotonin agonist
has_related_synonym: serotonin agonists
in_subset: 3 STAR
imported from: chebi.owl

neurotransmitter agent
type: Class
subclass of: drug
subclass of: pharmacological role
definition: A substance used for its pharmacological action on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function.
id: CHEBI:35942
has_obo_namespace: chebi_ontology
has_related_synonym: neurotransmitter agents
in_subset: 3 STAR
imported from: chebi.owl

antimicrobial drug
type: Class
subclass of: antimicrobial agent
subclass of: antiinfective agent
definition: A drug used to treat or prevent microbial infections.
id: CHEBI:36043
has_related_synonym: antimicrobial drugs
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

antiviral drug
type: Class
subclass of: antiviral agent
subclass of: antimicrobial drug
definition: A substance used in the prophylaxis or therapy of virus diseases.
id: CHEBI:36044
has_related_synonym: anti-viral drug
has_related_synonym: anti-virus drug
has_related_synonym: antiviral drugs
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

antibacterial drug
type: Class
subclass of: antibacterial agent
subclass of: antimicrobial drug
definition: A drug used to treat or prevent bacterial infections.
id: CHEBI:36047
database_cross_reference: Wikipedia:Antibacterial
has_related_synonym: antibacterial drugs
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

antitreponemal drug
type: Class
subclass of: antibacterial drug
definition: A drug used in the treatment of infections with bacteria of the genus Treponema.
id: CHEBI:36050
has_related_synonym: antitreponemal agent
has_related_synonym: antitreponemal drugs
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

antisyphilitic drug
type: Class
subclass of: antitreponemal drug
definition: A substance that is used in the treatment of syphilis.
id: CHEBI:36051
has_related_synonym: antisyphilitic agent
has_related_synonym: antisyphilitic agents
has_related_synonym: antisyphilitic drugs
has_related_synonym: antisyphilitics
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

acaricide drug
type: Class
subclass of: acaricide
subclass of: antiparasitic agent
definition: A drug used to treat infestations with arthropods of the subclass Acari (mites and ticks).
id: CHEBI:36053
database_cross_reference: Wikipedia:Acaricide
has_related_synonym: acaricide drugs
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

oxytocic
type: Class
subclass of: drug
definition: A drug that stimulates contraction of the myometrium. Oxytocics are used to induce labour, obstetric at term, to prevent or control postpartum or postabortion haemorrhage, and to assess foetal status in high risk pregnancies. They may also be used alone or with other drugs to induce abortions (abortifacients).
id: CHEBI:36063
has_obo_namespace: chebi_ontology
has_exact_synonym: oxytocic
has_related_synonym: oxytocic agents
has_related_synonym: oxytocic drugs
has_related_synonym: uterine stimulants
in_subset: 3 STAR
imported from: chebi.owl

taurocholate
type: Class
subclass of: molecular entity
charge: -1
has_exact_synonym: 2-[(3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholan-24-yl)amino]ethanesulfonate
monoisotopicmass: 514.28440
mass: 514.69610
definition: An organosulfonate oxoanion that is the conjugate base of taurocholic acid.
formula: C26H44NO7S
id: CHEBI:36257
inchi: InChI=1S/C26H45NO7S/c1-15(4-7-23(31)27-10-11-35(32,33)34)18-5-6-19-24-20(14-22(30)26(18,19)3)25(2)9-8-17(28)12-16(25)13-21(24)29/h15-22,24,28-30H,4-14H2,1-3H3,(H,27,31)(H,32,33,34)/p-1/t15-,16+,17-,18-,19+,20+,21-,22+,24+,25+,26-/m1/s1
database_cross_reference: MetaCyc:CPD-3743
database_cross_reference: Reaxys:3919947
inchikey: WBWWGRHZICKQGZ-HZAMXZRMSA-M
has_obo_namespace: chebi_ontology
has_exact_synonym: taurocholate
in_subset: 3 STAR
imported from: chebi.owl

local anaesthetic
type: Class
subclass of: anaesthetic
definition: Any member of a group of drugs that reversibly inhibit the propagation of signals along nerves. Wide variations in potency, stability, toxicity, water-solubility and duration of action determine the route used for administration, e.g. topical, intravenous, epidural or spinal block.
id: CHEBI:36333
has_related_synonym: Lokalanaesthetikum
has_related_synonym: anesthesique local
has_obo_namespace: chebi_ontology
has_exact_synonym: local anaesthetic
has_related_synonym: local anaesthetics
has_related_synonym: local anesthetics
in_subset: 3 STAR
imported from: chebi.owl

trypanocidal drug
type: Class
subclass of: antiprotozoal drug
definition: A drug used to treat or prevent infections caused by protozoal organisms belonging to the suborder Trypanosomatida.
id: CHEBI:36335
has_related_synonym: antitrypanosomal agent
has_related_synonym: antitrypanosomal agents
has_related_synonym: antitrypanosomal drug
has_related_synonym: antitrypanosomal drugs
has_obo_namespace: chebi_ontology
has_related_synonym: trypanocidal drugs
has_related_synonym: trypanocide
has_related_synonym: trypanosomicidal agents
in_subset: 3 STAR
imported from: chebi.owl

anabolic agent
type: Class
subclass of: hormone
definition: A compound which stimulates anabolism and inhibits catabolism. Anabolic agents stimulate the development of muscle mass, strength, and power.
id: CHEBI:36413
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

interferon inducer
type: Class
subclass of: drug
definition: An agent that promotes the production and release of interferons.
id: CHEBI:36710
has_obo_namespace: chebi_ontology
has_related_synonym: interferon inducers
in_subset: 3 STAR
imported from: chebi.owl

EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor
type: Class
subclass of: EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor
has_related_synonym: 3-hydroxy 3-methylglutaryl coenzymeA reductase phosphatase inhibitor
has_related_synonym: 3-hydroxy 3-methylglutaryl coenzymeA reductase phosphatase inhibitors
definition: Any EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of phosphoprotein phosphatase (EC 3.1.3.16).
has_related_synonym: Aspergillus awamori acid protein phosphatase inhibitor
has_related_synonym: Aspergillus awamori acid protein phosphatase inhibitors
has_related_synonym: BCKDH phosphatase inhibitor
has_related_synonym: BCKDH phosphatase inhibitors
id: CHEBI:37153
has_alternative_id: CHEBI:62670
has_related_synonym: EC 3.1.3.16 (protein serine/threonine phosphatase) inhibitors
has_related_synonym: EC 3.1.3.16 inhibitor
has_related_synonym: EC 3.1.3.16 inhibitors
has_related_synonym: HMG-CoA reductase phosphatase inhibitor
has_related_synonym: HMG-CoA reductase phosphatase inhibitors
database_cross_reference: Wikipedia:Phosphoprotein_phosphatase
database_cross_reference: Wikipedia:Protein_serine/threonine_phosphatase
has_related_synonym: branched-chain alpha-keto acid dehydrogenase phosphatase inhibitor
has_related_synonym: branched-chain alpha-keto acid dehydrogenase phosphatase inhibitors
has_related_synonym: calcineurin inhibitor
has_related_synonym: calcineurin inhibitors
has_related_synonym: casein phosphatase inhibitor
has_related_synonym: casein phosphatase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: phosphatase 2A inhibitor
has_related_synonym: phosphatase 2A inhibitors
has_related_synonym: phosphatase 2B inhibitor
has_related_synonym: phosphatase 2B inhibitors
has_related_synonym: phosphatase C-II inhibitor
has_related_synonym: phosphatase C-II inhibitors
has_related_synonym: phosphatase H-II inhibitor
has_related_synonym: phosphatase H-II inhibitors
has_related_synonym: phosphatase I inhibitor
has_related_synonym: phosphatase I inhibitors
has_related_synonym: phosphatase IB inhibitor
has_related_synonym: phosphatase IB inhibitors
has_related_synonym: phosphatase II inhibitor
has_related_synonym: phosphatase II inhibitors
has_related_synonym: phosphatase III inhibitor
has_related_synonym: phosphatase III inhibitors
has_related_synonym: phosphatase IV inhibitor
has_related_synonym: phosphatase IV inhibitors
has_related_synonym: phosphatase SP inhibitor
has_related_synonym: phosphatase SP inhibitors
has_related_synonym: phosphoprotein phosphatase (EC 3.1.3.16) inhibitor
has_related_synonym: phosphoprotein phosphatase (EC 3.1.3.16) inhibitors
has_related_synonym: phosphoprotein phosphatase inhibitor
has_related_synonym: phosphoprotein phosphatase inhibitors
has_related_synonym: phosphoprotein phosphohydrolase inhibitor
has_related_synonym: phosphoprotein phosphohydrolase inhibitors
has_related_synonym: phosphopyruvate dehydrogenase phosphatase inhibitor
has_related_synonym: phosphopyruvate dehydrogenase phosphatase inhibitors
has_related_synonym: phosphospectrin phosphatase inhibitor
has_related_synonym: phosphospectrin phosphatase inhibitors
has_related_synonym: polycation modulated (PCM-) phosphatase inhibitor
has_related_synonym: polycation modulated (PCM-) phosphatase inhibitors
has_related_synonym: protein D phosphatase inhibitor
has_related_synonym: protein D phosphatase inhibitors
has_related_synonym: protein phosphatase inhibitor
has_related_synonym: protein phosphatase inhibitors
has_related_synonym: protein phosphatase-1 inhibitor
has_related_synonym: protein phosphatase-1 inhibitors
has_related_synonym: protein phosphatase-2A inhibitor
has_related_synonym: protein phosphatase-2A inhibitors
has_related_synonym: protein phosphatase-2B inhibitor
has_related_synonym: protein phosphatase-2B inhibitors
has_related_synonym: protein phosphatase-2C inhibitor
has_related_synonym: protein phosphatase-2C inhibitors
has_related_synonym: protein serine/threonine phosphatase (EC 3.1.3.16) inhibitors
has_related_synonym: protein serine/threonine phosphatase inhibitor
has_related_synonym: protein serine/threonine phosphatase inhibitors
has_related_synonym: serine/threonine specific protein phosphatase inhibitor
has_related_synonym: serine/threonine specific protein phosphatase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

diagnostic imaging agent
type: Class
subclass of: diagnostic agent
definition: A substance administered to enhance contrast in images of the inside of the body obtained using X-rays, gamma-rays, sound waves, radio waves (MRI), or radioactive particles in order to diagnose disease.
id: CHEBI:37334
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

MRI contrast agent
type: Class
subclass of: diagnostic imaging agent
id: CHEBI:37335
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

radioactive imaging agent
type: Class
subclass of: diagnostic imaging agent
id: CHEBI:37336
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

ultrasound contrast agent
type: Class
subclass of: diagnostic imaging agent
id: CHEBI:37337
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

radioopaque medium
type: Class
subclass of: diagnostic imaging agent
definition: A substance having the property of absorbing, and therefore being opaque to, electromagnetic radiation, particularly X-rays.
id: CHEBI:37338
database_cross_reference: Wikipedia:Contrast_medium
has_obo_namespace: chebi_ontology
has_related_synonym: contrast media
has_related_synonym: radiocontrast agent
has_related_synonym: radiocontrast agents
has_related_synonym: radioopaque media
has_related_synonym: radiopaque media
has_related_synonym: radiopaque medium
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.7.6 (RNA polymerase) inhibitor
type: Class
subclass of: EC 2.7.7.* (nucleotidyltransferase) inhibitor
definition: An EC 2.7.7.* (nucleotidyltransferase) inhibitor that interferes with the action of RNA polymerase (EC 2.7.7.6).
has_related_synonym: C RNA formation factors inhibitor
has_related_synonym: C RNA formation factors inhibitors
has_related_synonym: C ribonucleic acid formation factors inhibitor
has_related_synonym: C ribonucleic acid formation factors inhibitors
id: CHEBI:37416
has_related_synonym: DNA-dependent RNA nucleotidyltransferase inhibitor
has_related_synonym: DNA-dependent RNA nucleotidyltransferase inhibitors
has_related_synonym: DNA-dependent RNA polymerase inhibitor
has_related_synonym: DNA-dependent RNA polymerase inhibitors
has_related_synonym: DNA-dependent ribonucleate nucleotidyltransferase inhibitor
has_related_synonym: DNA-dependent ribonucleate nucleotidyltransferase inhibitors
has_related_synonym: DNA-directed RNA polymerase inhibitor
has_related_synonym: DNA-directed RNA polymerase inhibitors
has_related_synonym: DNA-directed nucleoside-triphosphate:RNA nucleotidyltransferase inhibitor
has_related_synonym: DNA-directed nucleoside-triphosphate:RNA nucleotidyltransferase inhibitors
has_related_synonym: EC 2.7.7.6 (RNA polymerase) inhibitors
has_related_synonym: EC 2.7.7.6 inhibitor
has_related_synonym: EC 2.7.7.6 inhibitors
has_related_synonym: RNA nucleotidyltransferase (DNA-directed) inhibitor
has_related_synonym: RNA nucleotidyltransferase (DNA-directed) inhibitors
has_related_synonym: RNA nucleotidyltransferase inhibitor
has_related_synonym: RNA nucleotidyltransferase inhibitors
has_related_synonym: RNA polymerase (EC 2.7.7.6) inhibitor
has_related_synonym: RNA polymerase (EC 2.7.7.6) inhibitors
has_related_synonym: RNA polymerase I inhibitor
has_related_synonym: RNA polymerase I inhibitors
has_related_synonym: RNA polymerase II inhibitor
has_related_synonym: RNA polymerase II inhibitors
has_related_synonym: RNA polymerase III inhibitor
has_related_synonym: RNA polymerase III inhibitors
has_related_synonym: RNA polymerase inhibitor
has_related_synonym: RNA polymerase inhibitors
has_related_synonym: RNA transcriptase inhibitor
has_related_synonym: RNA transcriptase inhibitors
database_cross_reference: Wikipedia:RNA_polymerase
has_obo_namespace: chebi_ontology
has_related_synonym: deoxyribonucleic acid-dependent ribonucleic acid polymerase inhibitor
has_related_synonym: deoxyribonucleic acid-dependent ribonucleic acid polymerase inhibitors
has_related_synonym: directed RNA polymerase inhibitor
has_related_synonym: nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed) inhibitor
has_related_synonym: nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed) inhibitors
has_related_synonym: ribonucleate nucleotidyltransferase inhibitor
has_related_synonym: ribonucleate nucleotidyltransferase inhibitors
has_related_synonym: ribonucleate polymerase inhibitor
has_related_synonym: ribonucleate polymerase inhibitors
has_related_synonym: ribonucleic acid nucleotidyltransferase inhibitor
has_related_synonym: ribonucleic acid nucleotidyltransferase inhibitors
has_related_synonym: ribonucleic acid polymerase inhibitor
has_related_synonym: ribonucleic acid polymerase inhibitors
has_related_synonym: ribonucleic acid transcriptase inhibitor
has_related_synonym: ribonucleic acid transcriptase inhibitors
has_related_synonym: ribonucleic polymerase inhibitor
has_related_synonym: ribonucleic polymerase inhibitors
has_related_synonym: ribonucleic transcriptase inhibitor
has_related_synonym: ribonucleic transcriptase inhibitors
has_related_synonym: transcriptase inhibitor
has_related_synonym: transcriptase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

acid
type: Class
subclass of: chemical role
has_exact_synonym: Acid
definition: An acid is a molecular entity capable of donating a hydron (Bronsted acid) or capable of forming a covalent bond with an electron pair (Lewis acid).
has_alternative_id: CHEBI:13800
has_alternative_id: CHEBI:13801
has_alternative_id: CHEBI:22209
has_alternative_id: CHEBI:2426
id: CHEBI:37527
database_cross_reference: KEGG:C00174
has_related_synonym: Saeure
has_related_synonym: Saeuren
has_exact_synonym: acid
has_related_synonym: acide
has_related_synonym: acido
has_related_synonym: acids
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

protease inhibitor
type: Class
subclass of: EC 3.4.* (hydrolases acting on peptide bond) inhibitor
definition: A compound which inhibits or antagonizes the biosynthesis or actions of proteases (endopeptidases).
id: CHEBI:37670
database_cross_reference: Wikipedia:Protease_inhibitor_(biology)
has_obo_namespace: chebi_ontology
has_related_synonym: protease inhibitors
in_subset: 3 STAR
imported from: chebi.owl

protein kinase inhibitor
type: Class
subclass of: EC 2.7.* (P-containing group transferase) inhibitor
definition: An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of protein kinases.
id: CHEBI:37699
has_obo_namespace: chebi_ontology
has_related_synonym: protein kinase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.11.13 (protein kinase C) inhibitor
type: Class
subclass of: EC 2.7.11.* (protein-serine/threonine kinase) inhibitor
has_related_synonym: ATP:protein phosphotransferase (diacylglycerol-dependent) inhibitor
has_related_synonym: ATP:protein phosphotransferase (diacylglycerol-dependent) inhibitors
definition: An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of protein kinase C (EC 2.7.11.13).
id: CHEBI:37700
has_related_synonym: EC 2.7.11.13 (protein kinase C) inhibitors
has_related_synonym: EC 2.7.11.13 inhibitor
has_related_synonym: EC 2.7.11.13 inhibitors
has_related_synonym: PKC inhibitor
has_related_synonym: PKC inhibitors
has_related_synonym: PKCalpha inhibitor
has_related_synonym: PKCalpha inhibitors
has_related_synonym: PKCbeta inhibitor
has_related_synonym: PKCbeta inhibitors
has_related_synonym: PKCdelta inhibitor
has_related_synonym: PKCdelta inhibitors
has_related_synonym: PKCepsilon inhibitor
has_related_synonym: PKCepsilon inhibitors
has_related_synonym: PKCgamma inhibitor
has_related_synonym: PKCgamma inhibitors
has_related_synonym: PKCzeta inhibitor
has_related_synonym: PKCzeta inhibitors
has_related_synonym: PKN3 inhibitor
has_related_synonym: PKN3 inhibitors
has_related_synonym: Pkc1p inhibitor
has_related_synonym: Pkc1p inhibitors
has_related_synonym: STK24 inhibitor
has_related_synonym: STK24 inhibitors
has_related_synonym: cPKC inhibitor
has_related_synonym: cPKC inhibitors
has_related_synonym: cPKCalpha inhibitor
has_related_synonym: cPKCalpha inhibitors
has_related_synonym: cPKCbeta inhibitor
has_related_synonym: cPKCbeta inhibitors
has_related_synonym: cPKCgamma inhibitor
has_related_synonym: cPKCgamma inhibitors
has_related_synonym: calcium-dependent protein kinase C inhibitor
has_related_synonym: calcium-dependent protein kinase C inhibitors
has_related_synonym: calcium-independent protein kinase C inhibitor
has_related_synonym: calcium-independent protein kinase C inhibitors
has_related_synonym: calcium/phospholipid dependent protein kinase inhibitor
has_related_synonym: calcium/phospholipid dependent protein kinase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: nPKC inhibitor
has_related_synonym: nPKC inhibitors
has_related_synonym: nPKCdelta inhibitor
has_related_synonym: nPKCdelta inhibitors
has_related_synonym: nPKCepsilon inhibitor
has_related_synonym: nPKCepsilon inhibitors
has_related_synonym: nPKCeta inhibitor
has_related_synonym: nPKCeta inhibitors
has_related_synonym: nPKCtheta inhibitor
has_related_synonym: nPKCtheta inhibitors
has_related_synonym: protein kinase C (EC 2.7.11.13) inhibitor
has_related_synonym: protein kinase C (EC 2.7.11.13) inhibitors
has_related_synonym: protein kinase C inhibitor
has_related_synonym: protein kinase C inhibitors
has_related_synonym: protein kinase Cepsilon inhibitor
has_related_synonym: protein kinase Cepsilon inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.1.1.8 (cholinesterase) inhibitor
type: Class
subclass of: EC 3.1.1.* (carboxylic ester hydrolase) inhibitor
definition: An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of cholinesterase (EC 3.1.1.8).
has_related_synonym: BChE inhibitor
has_related_synonym: BChE inhibitors
has_related_synonym: BtChoEase inhibitor
has_related_synonym: BtChoEase inhibitors
id: CHEBI:37733
has_related_synonym: EC 3.1.1.8 (cholinesterase) inhibitors
has_related_synonym: EC 3.1.1.8 inhibitor
has_related_synonym: EC 3.1.1.8 inhibitors
has_related_synonym: anticholineesterase inhibitor
has_related_synonym: anticholineesterase inhibitors
has_related_synonym: anticholinesterase
has_related_synonym: anticholinesterases
has_related_synonym: benzoylcholinesterase inhibitor
has_related_synonym: benzoylcholinesterase inhibitors
has_related_synonym: butyrylcholine esterase inhibitor
has_related_synonym: butyrylcholine esterase inhibitors
has_related_synonym: butyrylcholinesterase inhibitor
has_related_synonym: butyrylcholinesterase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: choline esterase II (unspecific) inhibitor
has_related_synonym: choline esterase II (unspecific) inhibitors
has_related_synonym: choline esterase inhibitor
has_related_synonym: choline esterase inhibitors
has_related_synonym: cholinesterase (EC 3.1.1.8) inhibitor
has_related_synonym: cholinesterase (EC 3.1.1.8) inhibitors
has_related_synonym: cholinesterase inhibitor
has_related_synonym: non-specific cholinesterase inhibitor
has_related_synonym: non-specific cholinesterase inhibitors
has_related_synonym: propionylcholinesterase inhibitor
has_related_synonym: propionylcholinesterase inhibitors
has_related_synonym: pseudocholinesterase inhibitor
has_related_synonym: pseudocholinesterase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

growth hormone
type: Class
subclass of: hormone
definition: A hormone that specifically regulates growth.
database_cross_reference: CAS:9002-72-6
id: CHEBI:37845
has_related_synonym: GH
database_cross_reference: KEGG:C18181
has_related_synonym: Somatotropin
has_related_synonym: Wachstumshormon
has_obo_namespace: chebi_ontology
has_related_synonym: growth hormones
in_subset: 3 STAR
imported from: chebi.owl

plant hormone
type: Class
subclass of: hormone
subclass of: plant growth regulator
definition: A plant growth regulator that modulates the formation of stems, leaves and flowers, as well as the development and ripening of fruit. The term includes endogenous and non-endogenous compounds (e.g. active compounds produced by bacteria on the leaf surface) as well as semi-synthetic and fully synthetic compounds.
has_alternative_id: CHEBI:26158
id: CHEBI:37848
database_cross_reference: Wikipedia:Phytohormone
has_obo_namespace: chebi_ontology
has_related_synonym: phytohormone
has_related_synonym: phytohormones
has_related_synonym: plant growth factor
has_related_synonym: plant growth factors
has_related_synonym: plant growth hormone
has_related_synonym: plant growth hormones
has_related_synonym: plant hormones
in_subset: 3 STAR
imported from: chebi.owl

adrenergic agonist
type: Class
subclass of: adrenergic agent
definition: An agent that selectively binds to and activates adrenergic receptors.
id: CHEBI:37886
has_related_synonym: adrenergic agonists
has_related_synonym: adrenergic receptor agonist
has_related_synonym: adrenoceptor agonists
has_related_synonym: adrenomimetic
has_related_synonym: adrenomimetics
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

adrenergic antagonist
type: Class
subclass of: adrenergic agent
definition: An agent that binds to but does not activate adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists.
id: CHEBI:37887
has_related_synonym: adrenergic antagonists
has_related_synonym: adrenergic blockaders
has_related_synonym: adrenergic blocker
has_related_synonym: adrenergic blockers
has_related_synonym: adrenergic receptor blockaders
has_related_synonym: adrenoceptor antagonists
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

alpha-adrenergic antagonist
type: Class
subclass of: adrenergic antagonist
subclass of: alpha-adrenergic drug
definition: An agent that binds to but does not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous alpha-adrenergic agonists. alpha-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.
id: CHEBI:37890
has_related_synonym: alpha-adrenergic antagonists
has_related_synonym: alpha-adrenergic blocker
has_related_synonym: alpha-adrenergic blockers
has_related_synonym: alpha-adrenergic receptor blockaders
has_related_synonym: alpha-adrenoceptor antagonists
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

phenothiazine antipsychotic drug
type: Class
subclass of: first generation antipsychotic
id: CHEBI:37930
has_obo_namespace: chebi_ontology
has_related_synonym: phenothiazine antipsychotic drugs
has_related_synonym: phenothiazine antipsychotics
has_related_synonym: phenothiazine neuroleptics
in_subset: 3 STAR
imported from: chebi.owl

H1-receptor antagonist
type: Class
subclass of: histamine antagonist
id: CHEBI:37955
has_related_synonym: H1 antihistaminics
has_related_synonym: H1 receptor antagonists
has_related_synonym: H1 receptor blockaders
has_related_synonym: H1-receptor antagonists
definition: H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
has_related_synonym: H1-receptor blocker
has_related_synonym: H1-receptor blockers
database_cross_reference: PMID:22035879
has_obo_namespace: chebi_ontology
has_related_synonym: classical antihistamines
has_related_synonym: classical antihistaminics
in_subset: 3 STAR
imported from: chebi.owl

histamine antagonist
type: Class
subclass of: histaminergic drug
subclass of: antagonist
id: CHEBI:37956
definition: Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists.
database_cross_reference: PMID:22035879
database_cross_reference: Wikipedia:Antihistamines
has_related_synonym: antihistamine
has_related_synonym: antihistamines
has_related_synonym: antihistaminico
has_related_synonym: antihistaminics
has_obo_namespace: chebi_ontology
has_related_synonym: histamine receptor blocker
has_related_synonym: histamine receptor blockers
in_subset: 3 STAR
imported from: chebi.owl

histaminergic drug
type: Class
subclass of: neurotransmitter agent
id: CHEBI:37957
definition: Drugs used for their actions on histaminergic systems.
has_obo_namespace: chebi_ontology
has_related_synonym: histamine agents
has_related_synonym: histamine drugs
has_related_synonym: histaminergic agent
has_related_synonym: histaminergic agents
has_related_synonym: histaminergic drugs
in_subset: 3 STAR
imported from: chebi.owl

dye
type: Class
subclass of: application
id: CHEBI:37958
has_related_synonym: Farbstoff
has_related_synonym: Farbstoffe
has_obo_namespace: chebi_ontology
has_related_synonym: colorante
has_related_synonym: colorantes
has_related_synonym: dyes
has_related_synonym: teinture
has_related_synonym: teintures
in_subset: 3 STAR
imported from: chebi.owl

H2-receptor antagonist
type: Class
subclass of: histamine antagonist
id: CHEBI:37961
has_related_synonym: H2 receptor antagonists
has_related_synonym: H2 receptor blockaders
definition: H2-receptor antagonists are the drugs that selectively bind to but do not activate histamine H2 receptors, thereby blocking the actions of endogenous histamine.
has_related_synonym: H2-receptor blocker
has_related_synonym: H2-receptor blockers
has_obo_namespace: chebi_ontology
has_related_synonym: histamine H2 receptor antagonist
has_related_synonym: histamine H2 receptor antagonists
in_subset: 3 STAR
imported from: chebi.owl

adrenergic agent
type: Class
subclass of: neurotransmitter agent
definition: Any agent that acts on an adrenergic receptor or affects the life cycle of an adrenergic transmitter.
id: CHEBI:37962
has_related_synonym: adrenergic agents
has_related_synonym: adrenergic drug
has_related_synonym: adrenergic drugs
has_related_synonym: adrenergic neuron agents
has_related_synonym: adrenergics
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

triazine insecticide
type: Class
subclass of: insecticide
id: CHEBI:38060
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

antimalarial
type: Class
subclass of: antiplasmodial drug
definition: A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human.
id: CHEBI:38068
has_related_synonym: antimalarials
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

anti-arrhythmia drug
type: Class
subclass of: cardiovascular drug
definition: A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres.
id: CHEBI:38070
has_related_synonym: anti-arrhythmia agent
has_related_synonym: antiarrhythmic agent
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

cardiotonic drug
type: Class
subclass of: cardiovascular drug
definition: A drug that has a strengthening effect on the heart or that can increase cardiac output.
id: CHEBI:38147
has_related_synonym: cardiotonic drugs
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

phytosiderophore
type: Class
subclass of: iron(3+) chelator
subclass of: iron ionophore
definition: Any of low-molecular-mass iron(III)-chelating compounds produced by plants for the purpose of the transport and sequestration of iron.
has_alternative_id: CHEBI:26122
has_alternative_id: CHEBI:38117
id: CHEBI:38155
has_related_synonym: Phytosiderophor
has_obo_namespace: chebi_ontology
has_related_synonym: phytosiderophores
in_subset: 3 STAR
imported from: chebi.owl

iron chelator
type: Class
subclass of: chelator
id: CHEBI:38157
has_obo_namespace: chebi_ontology
has_related_synonym: iron chelating agent
has_related_synonym: iron chelating agents
has_related_synonym: iron chelators
in_subset: 3 STAR
imported from: chebi.owl

chelator
type: Class
subclass of: ligand
definition: A ligand with two or more separate binding sites that can bind to a single metallic central atom, forming a chelate.
has_alternative_id: CHEBI:23090
has_alternative_id: CHEBI:3585
id: CHEBI:38161
has_alternative_id: CHEBI:6789
has_related_synonym: Chelating agent
database_cross_reference: KEGG:C00917
database_cross_reference: KEGG:C02169
has_related_synonym: Metal chelator
has_obo_namespace: chebi_ontology
has_related_synonym: chelating agents
has_related_synonym: chelators
has_related_synonym: complexon
in_subset: 3 STAR
imported from: chebi.owl

iron(2+) chelator
type: Class
subclass of: iron chelator
id: CHEBI:38162
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

calcium channel blocker
type: Class
subclass of: calcium channel modulator
subclass of: antagonist
id: CHEBI:38215
definition: One of a class of drugs that acts by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools.
has_related_synonym: calcium channel antagonist
has_related_synonym: calcium channel antagonists
has_related_synonym: calcium channel blockers
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

phytotoxin
type: Class
subclass of: toxin
subclass of: plant metabolite
definition: Any toxin produced by a plant.
id: CHEBI:38231
has_obo_namespace: chebi_ontology
has_related_synonym: phytotoxins
in_subset: 3 STAR
imported from: chebi.owl

DNA polymerase inhibitor
type: Class
subclass of: EC 2.7.7.* (nucleotidyltransferase) inhibitor
definition: Any inhibitor of a DNA polymerase.
id: CHEBI:38234
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor
type: Class
subclass of: EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitor
has_related_synonym: 4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) inhibitor
has_related_synonym: 4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) inhibitors
has_related_synonym: 4-hydroxyphenylpyruvate dioxygenase inhibitor
has_related_synonym: 4-hydroxyphenylpyruvate dioxygenase inhibitors
has_related_synonym: 4-hydroxyphenylpyruvate hydroxylase inhibitor
has_related_synonym: 4-hydroxyphenylpyruvate hydroxylase inhibitors
has_related_synonym: 4-hydroxyphenylpyruvate:oxygen oxidoreductase (hydroxylating, decarboxylating) inhibitor
has_related_synonym: 4-hydroxyphenylpyruvate:oxygen oxidoreductase (hydroxylating, decarboxylating) inhibitors
has_related_synonym: 4-hydroxyphenylpyruvic acid dioxygenase inhibitor
has_related_synonym: 4-hydroxyphenylpyruvic acid dioxygenase inhibitors
definition: An EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 atoms of oxygen) inhibitor that interferes with the activity of 4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27).
id: CHEBI:38317
has_alternative_id: CHEBI:50380
has_related_synonym: EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitors
has_related_synonym: EC 1.13.11.27 inhibitor
has_related_synonym: EC 1.13.11.27 inhibitors
has_related_synonym: HPPD inhibitor
has_related_synonym: HPPD inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: p-hydroxyphenylpyruvate dioxygenase inhibitor
has_related_synonym: p-hydroxyphenylpyruvate dioxygenase inhibitors
has_related_synonym: p-hydroxyphenylpyruvate hydroxylase inhibitor
has_related_synonym: p-hydroxyphenylpyruvate hydroxylase inhibitors
has_related_synonym: p-hydroxyphenylpyruvate oxidase inhibitor
has_related_synonym: p-hydroxyphenylpyruvate oxidase inhibitors
has_related_synonym: p-hydroxyphenylpyruvic acid hydroxylase inhibitor
has_related_synonym: p-hydroxyphenylpyruvic acid hydroxylase inhibitors
has_related_synonym: p-hydroxyphenylpyruvic hydroxylase inhibitor
has_related_synonym: p-hydroxyphenylpyruvic hydroxylase inhibitors
has_related_synonym: p-hydroxyphenylpyruvic oxidase inhibitor
has_related_synonym: p-hydroxyphenylpyruvic oxidase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

cholinergic drug
type: Class
subclass of: neurotransmitter agent
definition: Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons.
id: CHEBI:38323
has_obo_namespace: chebi_ontology
has_related_synonym: cholinergic agent
has_related_synonym: cholinergic drugs
has_related_synonym: cholinomimetic
in_subset: 3 STAR
imported from: chebi.owl

cholinergic agonist
type: Class
subclass of: cholinergic drug
definition: Any drug that binds to and activates cholinergic receptors.
id: CHEBI:38324
has_related_synonym: acetylcholine agonist
has_related_synonym: acetylcholine agonists
has_related_synonym: acetylcholine receptor agonist
has_obo_namespace: chebi_ontology
has_related_synonym: cholinergic agonists
has_related_synonym: cholinomimetic
has_related_synonym: cholinomimetics
in_subset: 3 STAR
imported from: chebi.owl

muscarinic agonist
type: Class
subclass of: cholinergic agonist
definition: Any drug that binds to and activates a muscarinic cholinergic receptor.
id: CHEBI:38325
has_obo_namespace: chebi_ontology
has_related_synonym: muscarinic acetylcholine receptor agonist
has_related_synonym: muscarinic agonists
has_related_synonym: muscarinic cholinergic agonist
has_related_synonym: muscarinic cholinergic agonists
in_subset: 3 STAR
imported from: chebi.owl

ecdysone agonist
type: Class
subclass of: insect growth regulator
id: CHEBI:38456
has_obo_namespace: chebi_ontology
has_related_synonym: ecdysone agonists
has_related_synonym: ecdysone mimetic
in_subset: 3 STAR
imported from: chebi.owl

carbamate insecticide
type: Class
subclass of: insecticide
subclass of: EC 3.1.1.7 (acetylcholinesterase) inhibitor
id: CHEBI:38461
definition: Derivatives of carbamic acid with insecticidal properties of general formula ROC(=O)NR(1)R(2), where ROH is an alcohol, oxime, or phenol and R(1) is hydrogen or methyl. Like organophosphate insecticides, they are cholinesterase inhibitors, but carbamate insecticides differ in action from the organophosphates in that the inhibitory effect on cholinesterase is generally brief.
has_related_synonym: carbamate insecticides
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 3.1.1.7 (acetylcholinesterase) inhibitor
type: Class
subclass of: EC 3.1.1.* (carboxylic ester hydrolase) inhibitor
has_related_synonym: AChEI
has_related_synonym: AcCholE inhibitor
has_related_synonym: AcCholE inhibitors
definition: An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of enzyme acetylcholinesterase (EC 3.1.1.7), which helps breaking down of acetylcholine into choline and acetic acid.
id: CHEBI:38462
has_related_synonym: EC 3.1.1.7 (acetylcholinesterase) inhibitors
has_related_synonym: EC 3.1.1.7 inhibitor
has_related_synonym: EC 3.1.1.7 inhibitors
database_cross_reference: Wikipedia:Acetylcholinesterase_inhibitor
has_related_synonym: acetyl.beta-methylcholinesterase inhibitor
has_related_synonym: acetyl.beta-methylcholinesterase inhibitors
has_related_synonym: acetylcholine acetylhydrolase inhibitor
has_related_synonym: acetylcholine acetylhydrolase inhibitors
has_related_synonym: acetylcholine esterase inhibitor
has_related_synonym: acetylcholine hydrolase inhibitor
has_related_synonym: acetylcholine hydrolase inhibitors
has_related_synonym: acetylcholinesterase (EC 3.1.1.7) inhibitor
has_related_synonym: acetylcholinesterase (EC 3.1.1.7) inhibitors
has_related_synonym: acetylcholinesterase inhibitor
has_related_synonym: acetylcholinesterase inhibitors
has_related_synonym: acetylthiocholinesterase inhibitor
has_related_synonym: acetylthiocholinesterase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: choline esterase I inhibitor
has_related_synonym: choline esterase I inhibitors
has_related_synonym: cholinesterase inhibitor
has_related_synonym: cholinesterase inhibitors
has_related_synonym: true cholinesterase inhibitor
has_related_synonym: true cholinesterase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

electron-transport chain inhibitor
type: Class
subclass of: pathway inhibitor
id: CHEBI:38496
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

respiratory-chain inhibitor
type: Class
subclass of: electron-transport chain inhibitor
id: CHEBI:38497
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

mitochondrial NADH:ubiquinone reductase inhibitor
type: Class
subclass of: mitochondrial respiratory-chain inhibitor
subclass of: EC 1.6.5.3 [NADH:ubiquinone reductase (H(+)-translocating)] inhibitor
id: CHEBI:38498
has_obo_namespace: chebi_ontology
has_related_synonym: mitochondrial NADH dehydrogenase inhibitor
has_related_synonym: mitochondrial complex I inhibitor
has_related_synonym: mitochondrial complex I inhibitors
in_subset: 3 STAR
imported from: chebi.owl

mitochondrial cytochrome-bc1 complex inhibitor
type: Class
subclass of: mitochondrial respiratory-chain inhibitor
subclass of: cytochrome-bc1 complex inhibitor
id: CHEBI:38499
has_obo_namespace: chebi_ontology
has_related_synonym: mitochondrial complex III inhibitor
has_related_synonym: mitochondrial complex III inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.9.3.1 (cytochrome c oxidase) inhibitor
type: Class
subclass of: mitochondrial respiratory-chain inhibitor
subclass of: EC 1.9.3.* (oxidoreductase acting on donor heme group, oxygen as acceptor) inhibitor
definition: An EC 1.9.3.* (oxidoreductase acting on donor heme group, oxygen as acceptor) inhibitor that interferes with the action of cytochrome c oxidase (EC 1.9.3.1).
id: CHEBI:38500
has_alternative_id: CHEBI:38501
has_alternative_id: CHEBI:62966
has_related_synonym: CcO inhibitor
has_related_synonym: EC 1.9.3.1 (cytochrome c oxidase) inhibitors
has_related_synonym: EC 1.9.3.1 inhibitor
has_related_synonym: EC 1.9.3.1 inhibitors
has_related_synonym: NADH cytochrome c oxidase inhibitor
has_related_synonym: NADH cytochrome c oxidase inhibitors
database_cross_reference: PMID:12969439
has_related_synonym: Warburg's respiratory enzyme inhibitor
has_related_synonym: Warburg's respiratory enzyme inhibitors
database_cross_reference: Wikipedia:Cytochrome_c_oxidase
has_obo_namespace: chebi_ontology
has_related_synonym: complex IV (mitochondrial electron transport) inhibitor
has_related_synonym: complex IV (mitochondrial electron transport) inhibitors
has_related_synonym: cytochrome a3 inhibitor
has_related_synonym: cytochrome a3 inhibitors
has_related_synonym: cytochrome aa3 inhibitor
has_related_synonym: cytochrome aa3 inhibitors
has_related_synonym: cytochrome c oxidase (EC 1.9.3.1) inhibitor
has_related_synonym: cytochrome c oxidase (EC 1.9.3.1) inhibitors
has_related_synonym: cytochrome c oxidase inhibitor
has_related_synonym: cytochrome c oxidase inhibitors
has_related_synonym: cytochrome oxidase inhibitor
has_related_synonym: cytochrome oxidase inhibitors
has_related_synonym: cytochrome-c oxidase inhibitor
has_related_synonym: cytochrome-c oxidase inhibitors
has_related_synonym: ferrocytochrome c oxidase inhibitor
has_related_synonym: ferrocytochrome c oxidase inhibitors
has_related_synonym: ferrocytochrome-c:oxygen oxidoreductase inhibitor
has_related_synonym: ferrocytochrome-c:oxygen oxidoreductase inhibitors
has_related_synonym: indophenol oxidase inhibitor
has_related_synonym: indophenol oxidase inhibitors
has_related_synonym: indophenolase inhibitor
has_related_synonym: indophenolase inhibitors
has_related_synonym: mitochondrial complex IV inhibitor
has_related_synonym: mitochondrial complex IV inhibitors
has_related_synonym: mitochondrial cytochrome-c oxidase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

cytochrome-bc1 complex inhibitor
type: Class
subclass of: respiratory-chain inhibitor
id: CHEBI:38502
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

EC 1.6.5.3 [NADH:ubiquinone reductase (H(+)-translocating)] inhibitor
type: Class
subclass of: respiratory-chain inhibitor
subclass of: EC 1.6.5.* (oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor) inhibitor
definition: A respiratory-chain inhibitor that interferes with the action of the the enzyme NADH:ubiquinone reductase (H(+)-translocating), EC 1.6.5.3.
id: CHEBI:38503
has_related_synonym: DPNH-coenzyme Q reductase inhibitor
has_related_synonym: DPNH-ubiquinone reductase inhibitor
has_related_synonym: EC 1.6.5.3 (NADH:ubiquinone reductase (H(+)-translocating)) inhibitor
has_related_synonym: EC 1.6.5.3 (NADH:ubiquinone reductase (H(+)-translocating)) inhibitors
has_related_synonym: EC 1.6.5.3 [NADH:ubiquinone reductase (H(+)-translocating)] inhibitors
has_related_synonym: EC 1.6.5.3 inhibitor
has_related_synonym: EC 1.6.5.3 inhibitors
has_related_synonym: NADH coenzyme Q1 reductase inhibitor
has_related_synonym: NADH coenzyme Q1 reductase inhibitors
has_related_synonym: NADH dehydrogenase (ubiquinone) inhibitor
has_related_synonym: NADH dehydrogenase (ubiquinone) inhibitors
has_related_synonym: NADH-CoQ oxidoreductase inhibitor
has_related_synonym: NADH-CoQ oxidoreductase inhibitors
has_related_synonym: NADH-CoQ reductase inhibitor
has_related_synonym: NADH-CoQ reductase inhibitors
has_related_synonym: NADH-Q6 oxidoreductase inhibitor
has_related_synonym: NADH-coenzyme Q oxidoreductase inhibitors
has_related_synonym: NADH-coenzyme Q reductase inhibitor
has_related_synonym: NADH-coenzyme Q reductase inhibitors
has_related_synonym: NADH-ubiquinone oxidoreductase inhibitor
has_related_synonym: NADH-ubiquinone oxidoreductase inhibitors
has_related_synonym: NADH-ubiquinone reductase inhibitor
has_related_synonym: NADH-ubiquinone reductase inhibitors
has_related_synonym: NADH-ubiquinone-1 reductase inhibitor
has_related_synonym: NADH-ubiquinone-1 reductase inhibitors
has_related_synonym: NADH2 dehydrogenase (ubiquinone) inhibitor
has_related_synonym: NADH:ubiquinone oxidoreductase complex inhibitor
has_related_synonym: NADH:ubiquinone oxidoreductase inhibitor
has_related_synonym: NADH:ubiquinone oxidoreductase inhibitors
has_related_synonym: NADH:ubiquinone reductase (H(+)-translocating) inhibitor
has_related_synonym: NADH:ubiquinone reductase (H(+)-translocating) inhibitors
has_related_synonym: NADH:ubiquinone reductase (H+-translocating) inhibitor
has_related_synonym: NADH:ubiquinone reductase inhibitor
database_cross_reference: Wikipedia:NADH_dehydrogenase_(ubiquinone)
has_obo_namespace: chebi_ontology
has_related_synonym: coenzyme Q reductase
has_related_synonym: complex 1 dehydrogenase inhibitor
has_related_synonym: complex I (NADH:Q1 oxidoreductase) inhibitors
has_related_synonym: complex I (electron transport chain) inhibitors
has_related_synonym: complex I (mitochondrial electron transport) inhibitors
has_related_synonym: dihydronicotinamide adenine dinucleotide-coenzyme Q reductase inhibitor
has_related_synonym: electron transfer complex I inhibitor
has_related_synonym: electron transfer complex I inhibitors
has_related_synonym: mitochondrial electron transport complex 1 inhibitor
has_related_synonym: mitochondrial electron transport complex I inhibitor
has_related_synonym: mitochondrial electron transport complex I inhibitors
has_related_synonym: reduced nicotinamide adenine dinucleotide-coenzyme Q reductase inhibitor
has_related_synonym: reduced nicotinamide adenine dinucleotide-coenzyme Q reductase inhibitors
has_related_synonym: type 1 dehydrogenase inhibitor
has_related_synonym: type 1 dehydrogenase inhibitors
has_related_synonym: ubiquinone reductase inhibitor
has_related_synonym: ubiquinone reductase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

rosuvastatin
type: Class
subclass of: molecular entity
has_related_synonym: (3R,5S,6E)-7-(4-(4-fluorophenyl)-6-(1-methylethyl)-2-(ethyl(methylsulfonyl)amino)-5-pyrimidinyl)-3,5-dihydroxy-6-heptenoic acid
has_exact_synonym: (3R,5S,6E)-7-{4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid
has_related_synonym: (3R,5S,6E)-7-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid
charge: 0
monoisotopicmass: 481.16828
mass: 481.53800
definition: A dihydroxy monocarboxylic acid that is (6E)-7-{4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidin-5-yl} hept-6-enoic acid carrying two hydroxy substituents at positions 3 and 5 (the 3R,5S-diastereomer).
inchikey: BPRHUIZQVSMCRT-VEUZHWNKSA-N
formula: C22H28FN3O6S
database_cross_reference: CAS:287714-41-4
id: CHEBI:38545
database_cross_reference: DrugBank:DB01098
database_cross_reference: Drug_Central:2406
database_cross_reference: HMDB:HMDB0015230
inchi: InChI=1S/C22H28FN3O6S/c1-13(2)20-18(10-9-16(27)11-17(28)12-19(29)30)21(14-5-7-15(23)8-6-14)25-22(24-20)26(3)33(4,31)32/h5-10,13,16-17,27-28H,11-12H2,1-4H3,(H,29,30)/b10-9+/t16-,17-/m1/s1
database_cross_reference: KEGG:D08492
database_cross_reference: PMID:17970755
database_cross_reference: PMID:18509206
database_cross_reference: PMID:19724024
database_cross_reference: PMID:19956889
database_cross_reference: PMID:23806820
database_cross_reference: PMID:23881596
database_cross_reference: PMID:23944632
database_cross_reference: PMID:24072337
database_cross_reference: PMID:24076283
database_cross_reference: PMID:24076297
database_cross_reference: PMID:24156555
database_cross_reference: PMID:24163149
database_cross_reference: PMID:24230979
database_cross_reference: PMID:24253250
database_cross_reference: PMID:24259612
database_cross_reference: PMID:24304551
database_cross_reference: PMID:24333476
database_cross_reference: PMID:24353409
database_cross_reference: PMID:24410968
database_cross_reference: PMID:24417785
database_cross_reference: PMID:24434545
database_cross_reference: PMID:24440231
database_cross_reference: PMID:24440960
database_cross_reference: PMID:24444439
database_cross_reference: PMID:24452083
database_cross_reference: PMID:24456217
database_cross_reference: PMID:24467235
database_cross_reference: Patent:US2013035316
database_cross_reference: Reaxys:9670765
database_cross_reference: Wikipedia:Rosuvastatin
has_obo_namespace: chebi_ontology
has_related_synonym: rosuvastatin
in_subset: 3 STAR
imported from: chebi.owl

EC 1.4.3.4 (monoamine oxidase) inhibitor
type: Class
subclass of: EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor
definition: An EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor that interferes with the action of monoamine oxidase (EC 1.4.3.4).
id: CHEBI:38623
has_related_synonym: EC 1.4.3.4 (monoamine oxidase) inhibitors
has_related_synonym: EC 1.4.3.4 inhibitor
has_related_synonym: EC 1.4.3.4 inhibitors
has_related_synonym: MAO A inhibitor
has_related_synonym: MAO A inhibitors
has_related_synonym: MAO B inhibitor
has_related_synonym: MAO B inhibitors
has_related_synonym: MAO inhibitor
has_related_synonym: MAO inhibitors
has_related_synonym: MAO-A inhibitor
has_related_synonym: MAO-A inhibitors
has_related_synonym: MAO-B inhibitor
has_related_synonym: MAO-B inhibitors
database_cross_reference: Wikipedia:Monoamine_oxidase_inhibitor
has_related_synonym: adrenalin oxidase inhibitor
has_related_synonym: adrenalin oxidase inhibitors
has_related_synonym: adrenaline oxidase inhibitor
has_related_synonym: adrenaline oxidase inhibitors
has_related_synonym: amine oxidase (flavin-containing) inhibitor
has_related_synonym: amine oxidase (flavin-containing) inhibitors
has_related_synonym: amine:oxygen oxidoreductase (deaminating) (flavin-containing) inhibitor
has_related_synonym: amine:oxygen oxidoreductase (deaminating) (flavin-containing) inhibitors
has_related_synonym: amine:oxygen oxidoreductase (deaminating) inhibitor
has_related_synonym: amine:oxygen oxidoreductase (deaminating) inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: epinephrine oxidase inhibitor
has_related_synonym: epinephrine oxidase inhibitors
has_related_synonym: monoamine oxidase (EC 1.4.3.4) inhibitor
has_related_synonym: monoamine oxidase (EC 1.4.3.4) inhibitors
has_related_synonym: monoamine oxidase A inhibitor
has_related_synonym: monoamine oxidase A inhibitors
has_related_synonym: monoamine oxidase B inhibitor
has_related_synonym: monoamine oxidase B inhibitors
has_related_synonym: monoamine oxidase inhibitor
has_related_synonym: monoamine oxidase inhibitors
has_related_synonym: monoamine:O2 oxidoreductase (deaminating) inhibitor
has_related_synonym: monoamine:O2 oxidoreductase (deaminating) inhibitors
has_related_synonym: serotonin deaminase inhibitor
has_related_synonym: serotonin deaminase inhibitors
has_related_synonym: tyraminase inhibitor
has_related_synonym: tyraminase inhibitors
has_related_synonym: tyramine oxidase inhibitor
has_related_synonym: tyramine oxidase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

membrane transport modulator
type: Class
subclass of: biophysical role
definition: Any agent that affects the transport of molecular entities across a biological membrane.
id: CHEBI:38632
has_obo_namespace: chebi_ontology
has_related_synonym: membrane transport modulators
in_subset: 3 STAR
imported from: chebi.owl

sodium channel blocker
type: Class
subclass of: sodium channel modulator
definition: An agent that inhibits sodium influx through cell membranes.
id: CHEBI:38633
has_related_synonym: Na channel blocker
has_obo_namespace: chebi_ontology
has_related_synonym: sodium channel blockers
in_subset: 3 STAR
imported from: chebi.owl

voltage-gated sodium channel blocker
type: Class
subclass of: sodium channel blocker
definition: Any sodium channel blocker that interferes with the activity of voltage-gated sodium channels.
id: CHEBI:38634
has_related_synonym: Nav channel blocker
has_related_synonym: Nav channel blockers
has_obo_namespace: chebi_ontology
has_related_synonym: voltage-dependent sodium channel blockers
in_subset: 3 STAR
imported from: chebi.owl

tyrosine kinase inhibitor
type: Class
subclass of: protein kinase inhibitor
definition: Any protein kinase inhibitor that interferes with the action of tyrosine kinase.
id: CHEBI:38637
has_related_synonym: TKI inhibitor
has_related_synonym: TKI inhibitors
database_cross_reference: Wikipedia:Tyrosine-kinase_inhibitor
has_obo_namespace: chebi_ontology
has_related_synonym: protein tyrosine kinase inhibitor
has_related_synonym: protein tyrosine kinase inhibitors
has_related_synonym: tyrosine kinase inhibitors
has_related_synonym: tyrphostin
has_related_synonym: tyrphostins
in_subset: 3 STAR
imported from: chebi.owl

pediculicide
type: Class
subclass of: insecticide
id: CHEBI:38706
definition: Substance used to treat lice (genus Pediculus) infestation.
has_obo_namespace: chebi_ontology
has_related_synonym: pediculicides
in_subset: 3 STAR
imported from: chebi.owl

calcium channel agonist
type: Class
subclass of: calcium channel modulator
definition: Agents that increase calcium influx into calcium channels of excitable tissues.
id: CHEBI:38807
has_related_synonym: calcium channel activator
has_related_synonym: calcium channel activators
has_related_synonym: calcium channel agonists
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

calcium channel modulator
type: Class
subclass of: membrane transport modulator
definition: A membrane transport modulator that is able to regulate intracellular calcium levels.
id: CHEBI:38808
has_related_synonym: calcium channel modulators
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

ryanodine receptor modulator
type: Class
subclass of: calcium channel modulator
id: CHEBI:38809
has_related_synonym: RyR modulator
has_obo_namespace: chebi_ontology
has_related_synonym: ryanodine receptor modulators
has_related_synonym: ryanodine-sensitive calcium channel modulator
has_related_synonym: ryanodine-sensitive calcium-release channel modulator
in_subset: 3 STAR
imported from: chebi.owl

nonionic surfactant
type: Class
subclass of: surfactant
definition: A surfactant with an uncharged hydrophilic headgroup.
id: CHEBI:38828
has_obo_namespace: chebi_ontology
has_related_synonym: non-ionic surfactant
has_related_synonym: nonionic surfactants
in_subset: 3 STAR
imported from: chebi.owl

blood substitute
type: Class
subclass of: pharmaceutical
definition: A substance that can carry oxygen to and carbon dioxide away from the tissues when introduced into the blood stream. Blood substitutes are used to replace hemoglobin in severe hemorrhage and also to perfuse isolated organs.
id: CHEBI:38849
has_related_synonym: artificial blood
has_related_synonym: blood substitutes
has_obo_namespace: chebi_ontology
has_related_synonym: oxygen carrier
in_subset: 3 STAR
imported from: chebi.owl

anaesthetic
type: Class
subclass of: drug
has_related_synonym: Anaesthetika
has_related_synonym: Anaesthetikum
id: CHEBI:38867
definition: Substance which produces loss of feeling or sensation.
has_exact_synonym: anaesthetic
has_related_synonym: anaesthetics
has_related_synonym: anesthetic agent
has_related_synonym: anesthetic drug
has_related_synonym: anesthetics
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

general anaesthetic
type: Class
subclass of: anaesthetic
has_related_synonym: Allgemeinanaesthetika
has_related_synonym: Allgemeinanaesthetikum
id: CHEBI:38869
definition: Substance that produces loss of consciousness.
has_obo_namespace: chebi_ontology
has_exact_synonym: general anaesthetic
has_related_synonym: general anaesthetics
has_related_synonym: general anesthetics
in_subset: 3 STAR
imported from: chebi.owl

inhalation anaesthetic
type: Class
subclass of: general anaesthetic
id: CHEBI:38870
has_related_synonym: Inhalationsanaesthetika
has_related_synonym: Inhalationsanaesthetikum
has_related_synonym: Inhalationsnarkotika
has_related_synonym: Inhalationsnarkotikum
has_related_synonym: anesthetic gases
has_obo_namespace: chebi_ontology
has_related_synonym: inhalation anesthetics
in_subset: 3 STAR
imported from: chebi.owl

intravenous anaesthetic
type: Class
subclass of: general anaesthetic
id: CHEBI:38877
has_obo_namespace: chebi_ontology
has_related_synonym: i.v.-Anaesthetika
has_related_synonym: i.v.-Anaesthetikum
has_related_synonym: intravenous anesthetics
in_subset: 3 STAR
imported from: chebi.owl

schistosomicide drug
type: Class
subclass of: antiplatyhelmintic drug
id: CHEBI:38941
definition: Drugs that used to treat infestations by flukes (trematodes) of the genus Schistosoma.
has_related_synonym: antischistosoma
has_related_synonym: antischistosomal drug
has_obo_namespace: chebi_ontology
has_related_synonym: schistosomicide
has_related_synonym: schistosomicide drugs
has_related_synonym: schistosomicides
in_subset: 3 STAR
imported from: chebi.owl

ectoparasiticide
type: Class
subclass of: antiparasitic agent
id: CHEBI:38956
database_cross_reference: Wikipedia:Ectoparasiticide
has_obo_namespace: chebi_ontology
has_related_synonym: ectoparasiticides
in_subset: 3 STAR
imported from: chebi.owl

GABA-gated chloride channel antagonist
type: Class
subclass of: membrane transport modulator
subclass of: antagonist
id: CHEBI:38999
has_related_synonym: GABA-gated chloride channel antagonists
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

sodium channel modulator
type: Class
subclass of: membrane transport modulator
id: CHEBI:39000
has_obo_namespace: chebi_ontology
has_related_synonym: sodium channel modulators
in_subset: 3 STAR
imported from: chebi.owl

Good's buffer substance
type: Class
subclass of: buffer
definition: Any member of a collection of zwitterionic buffer substances selected or devised for suitability in experimental biological systems according to a number of predetermined criteria. Named after Dr. Norman Good.
id: CHEBI:39011
has_related_synonym: Good buffer substance
has_related_synonym: Good's buffer
has_related_synonym: Good's buffers
database_cross_reference: Wikipedia:Good's_buffers
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

pyrethroid ester insecticide
type: Class
subclass of: pyrethroid insecticide
id: CHEBI:39116
has_obo_namespace: chebi_ontology
has_related_synonym: pyrethroid ester insecticides
in_subset: 3 STAR
imported from: chebi.owl

Bronsted acid
type: Class
subclass of: donor
subclass of: acid
definition: A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
has_exact_synonym: Bronsted acid
has_related_synonym: Bronsted-Saeure
id: CHEBI:39141
has_related_synonym: acide de Bronsted
has_obo_namespace: chebi_ontology
has_related_synonym: donneur d'hydron
has_related_synonym: hydron donor
in_subset: 3 STAR
imported from: chebi.owl

Bronsted base
type: Class
subclass of: acceptor
subclass of: base
definition: A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
has_exact_synonym: Bronsted base
has_related_synonym: Bronsted-Base
id: CHEBI:39142
has_related_synonym: accepteur d'hydron
has_related_synonym: base de Bronsted
has_obo_namespace: chebi_ontology
has_related_synonym: hydron acceptor
in_subset: 3 STAR
imported from: chebi.owl

Lewis acid
type: Class
subclass of: acceptor
subclass of: acid
definition: A molecular entity that is an electron-pair acceptor and therefore able to form a covalent bond with an electron-pair donor (Lewis base), thereby producing a Lewis adduct.
id: CHEBI:39143
has_exact_synonym: Lewis acid
has_related_synonym: Lewis-Saeure
has_related_synonym: accepteur d'une paire d'electrons
has_related_synonym: acide de Lewis
has_obo_namespace: chebi_ontology
has_related_synonym: electron acceptor
has_related_synonym: electron-pair acceptor
in_subset: 3 STAR
imported from: chebi.owl

Lewis base
type: Class
subclass of: donor
subclass of: base
definition: A molecular entity able to provide a pair of electrons and thus capable of forming a covalent bond with an electron-pair acceptor (Lewis acid), thereby producing a Lewis adduct.
id: CHEBI:39144
has_exact_synonym: Lewis base
has_related_synonym: Lewis-Base
has_related_synonym: base de Lewis
has_obo_namespace: chebi_ontology
has_related_synonym: donneur d'une paire d'electrons
has_related_synonym: electron donor
in_subset: 3 STAR
imported from: chebi.owl

antibiotic insecticide
type: Class
subclass of: insecticide
subclass of: antibiotic pesticide
id: CHEBI:39208
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

antibiotic pesticide
type: Class
subclass of: pesticide
subclass of: antimicrobial agent
id: CHEBI:39215
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

antibiotic acaricide
type: Class
subclass of: acaricide
subclass of: antibiotic pesticide
id: CHEBI:39216
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

antibiotic nematicide
type: Class
subclass of: nematicide
subclass of: antibiotic pesticide
id: CHEBI:39217
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

pyrethroid ester acaricide
type: Class
subclass of: acaricide
id: CHEBI:39259
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

fumigant
type: Class
subclass of: pesticide
definition: A volatile or volatilizable chemical compound utilized for control of pests in buildings, soil, grain, as well as during processing of goods to be imported or exported to prevent transfer of exotic organisms.
id: CHEBI:39276
database_cross_reference: Wikipedia:Fumigation
has_obo_namespace: chebi_ontology
has_related_synonym: fumigant pesticide
has_related_synonym: fumigants
in_subset: 3 STAR
imported from: chebi.owl

fumigant insecticide
type: Class
subclass of: insecticide
subclass of: fumigant
id: CHEBI:39277
has_obo_namespace: chebi_ontology
has_related_synonym: fumigant insecticides
in_subset: 3 STAR
imported from: chebi.owl

sulfite ester acaricide
type: Class
subclass of: acaricide
id: CHEBI:39301
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

mite growth regulator
type: Class
subclass of: acaricide
subclass of: growth regulator
id: CHEBI:39316
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

growth regulator
type: Class
subclass of: biological role
definition: Any chemical substance that inhibits the life-cycle of an organism.
id: CHEBI:39317
has_obo_namespace: chebi_ontology
has_related_synonym: growth regulators
in_subset: 3 STAR
imported from: chebi.owl

tetrazine acaricide
type: Class
subclass of: acaricide
id: CHEBI:39318
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

pyrethroid ether insecticide
type: Class
subclass of: pyrethroid insecticide
id: CHEBI:39351
has_obo_namespace: chebi_ontology
has_related_synonym: pyrethroid ether insecticides
in_subset: 3 STAR
imported from: chebi.owl

pyrethroid ether acaricide
type: Class
subclass of: acaricide
id: CHEBI:39369
has_obo_namespace: chebi_ontology
has_related_synonym: pyrethroid ether acaricides
in_subset: 3 STAR
imported from: chebi.owl

homopteran inhibitor of chitin biosynthesis
type: Class
subclass of: chitin synthesis inhibitor
id: CHEBI:39378
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

lepidopteran inhibitor of chitin biosynthesis
type: Class
subclass of: chitin synthesis inhibitor
id: CHEBI:39379
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

bridged diphenyl acaricide
type: Class
subclass of: acaricide
id: CHEBI:39412
has_related_synonym: bridged diphenyl acaricides
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

dinitrophenol insecticide
type: Class
subclass of: insecticide
id: CHEBI:39415
has_obo_namespace: chebi_ontology
has_related_synonym: dinitrophenol insecticides
in_subset: 3 STAR
imported from: chebi.owl

fluorescent probe
type: Class
subclass of: probe
definition: A role played by a fluorescent molecular entity used to study the microscopic environment by fluorescence spectroscopy.
id: CHEBI:39442
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

antiglaucoma drug
type: Class
subclass of: ophthalmology drug
definition: Any drug which can be used to prevent or alleviate glaucoma, a disease in which the optic nerve is damaged, resulting in progressive, irreversible loss of vision. It is often, though not always, associated with increased pressure of the fluid in the eye.
id: CHEBI:39456
has_related_synonym: anti-glaucoma agent
has_related_synonym: anti-glaucoma agents
has_related_synonym: anti-glaucoma drug
has_related_synonym: anti-glaucoma drugs
has_related_synonym: antiglaucoma agent
has_related_synonym: antiglaucoma drugs
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

dextromethorphan
type: Class
subclass of: molecular entity
has_related_synonym: (+)-3-methoxy-N-methylmorphinan
has_related_synonym: (+)-dextromethorphan
has_exact_synonym: (4aS,10S,10aS)-6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene
has_related_synonym: (9alpha,13alpha,14alpha)-3-methoxy-17-methylmorphinan
charge: 0
monoisotopicmass: 271.19361
mass: 271.404
has_related_synonym: 3-methoxy-17-methyl-9alpha,13alpha,14alpha-morphinan
has_exact_synonym: 3-methoxy-17-methyl-9alpha,13alpha,14alpha-morphinan
definition: A 6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene in which the sterocenters at positions 4a, 10 and 10a have S-configuration. It is a prodrug of dextrorphan and used as an antitussive drug for suppressing cough.
has_related_synonym: Albutussin
has_related_synonym: Antussan
has_related_synonym: BA 2666
has_related_synonym: BA-2666
has_related_synonym: Balminil DM
has_related_synonym: Benylin DM
formula: C18H25NO
database_cross_reference: CAS:125-71-3
id: CHEBI:4470
has_alternative_id: CHEBI:92579
has_related_synonym: Calmylin
has_related_synonym: D-methorphan
has_related_synonym: DXM
has_related_synonym: Delsym
has_related_synonym: Dextromorphan
database_cross_reference: DrugBank:DB00514
database_cross_reference: Drug_Central:842
database_cross_reference: HMDB:HMDB0001920
inchi: InChI=1S/C18H25NO/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18/h6-7,12,15,17H,3-5,8-11H2,1-2H3/t15-,17+,18+/m1/s1
database_cross_reference: KEGG:C06947
database_cross_reference: KEGG:D03742
database_cross_reference: LINCS:LSM-2726
inchikey: MKXZASYAUGDDCJ-NJAFHUGGSA-N
has_related_synonym: Medicon
database_cross_reference: PMID:10869398
database_cross_reference: PMID:12711372
database_cross_reference: PMID:15505150
database_cross_reference: PMID:17157116
database_cross_reference: PMID:17461892
database_cross_reference: PMID:17573115
database_cross_reference: PMID:18160193
database_cross_reference: PMID:18198471
database_cross_reference: PMID:24269965
database_cross_reference: PMID:2660263
database_cross_reference: PMID:31094746
database_cross_reference: PMID:7976530
database_cross_reference: PMID:8158182
database_cross_reference: PMID:9705419
database_cross_reference: Reaxys:88549
has_related_synonym: Romilar
has_related_synonym: Tusilan
database_cross_reference: Wikipedia:Dextromethorphan
has_obo_namespace: chebi_ontology
has_related_synonym: d-Methorphan
has_related_synonym: destrometerfano
has_related_synonym: dextromethorfan
has_related_synonym: dextromethorphan
has_related_synonym: dextromethorphane
has_related_synonym: dextromethorphanum
has_related_synonym: dextrometorfano
in_subset: 3 STAR
imported from: chebi.owl

propofol
type: Class
subclass of: molecular entity
charge: 0
monoisotopicmass: 178.13577
mass: 178.27072
has_related_synonym: 2,6-BIS(1-METHYLETHYL)PHENOL
has_related_synonym: 2,6-Diisopropylphenol
has_related_synonym: 2,6-bis(1-methylethyl)phenol
has_exact_synonym: 2,6-bis(propan-2-yl)phenol
definition: A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
database_cross_reference: Beilstein:1866484
formula: C12H18O
database_cross_reference: CAS:2078-54-8
smiles: CC(C)c1cccc(C(C)C)c1O
has_alternative_id: CHEBI:44914
id: CHEBI:44915
has_alternative_id: CHEBI:8495
has_related_synonym: Diprivan
has_related_synonym: Disoprivan
has_related_synonym: Disoprofol
database_cross_reference: DrugBank:DB00818
database_cross_reference: Drug_Central:2302
inchi: InChI=1S/C12H18O/c1-8(2)10-6-5-7-11(9(3)4)12(10)13/h5-9,13H,1-4H3
database_cross_reference: KEGG:C07523
database_cross_reference: KEGG:D00549
database_cross_reference: LINCS:LSM-3847
inchikey: OLBCVFGFOZPWHH-UHFFFAOYSA-N
database_cross_reference: PDBeChem:PFL
has_exact_synonym: Propofol
has_related_synonym: Rapinovet
database_cross_reference: VSDB:1846
database_cross_reference: Wikipedia:Propofol
has_obo_namespace: chebi_ontology
has_related_synonym: propofol
has_related_synonym: propofolum
in_subset: 3 STAR
imported from: chebi.owl

troleandomycin
type: Class
subclass of: molecular entity
has_exact_synonym: (3R,5R,6S,7R,8R,11R,12S,13R,14S,15S)-12-[(4-O-acetyl-2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)oxy]-14-{[2-O-acetyl-3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy}-5,7,8,11,13,15-hexamethyl-4,10-dioxo-1,9-dioxaspiro[2.13]hexadecan-6-yl acetate
charge: 0
monoisotopicmass: 813.45107
mass: 813.96840
definition: A semi-synthetic macrolide antibiotic obtained by acetylation of the three free hydroxy groups of oleandomycin. Troleandomycin is only found in individuals that have taken the drug.
formula: C41H67NO15
database_cross_reference: CAS:2751-09-9
has_alternative_id: CHEBI:32267
id: CHEBI:45735
database_cross_reference: DrugBank:DB01361
database_cross_reference: Drug_Central:2769
database_cross_reference: HMDB:HMDB0015448
inchi: InChI=1S/C41H67NO15/c1-19-17-41(18-49-41)38(46)23(5)34(53-27(9)43)21(3)25(7)52-39(47)24(6)35(56-32-16-31(48-14)36(26(8)51-32)54-28(10)44)22(4)33(19)57-40-37(55-29(11)45)30(42(12)13)15-20(2)50-40/h19-26,30-37,40H,15-18H2,1-14H3/t19-,20+,21-,22+,23+,24+,25+,26-,30-,31-,32-,33-,34-,35-,36-,37+,40-,41+/m0/s1
database_cross_reference: KEGG:C12753
database_cross_reference: KEGG:D01322
database_cross_reference: LINCS:LSM-5510
database_cross_reference: LIPID_MAPS_instance:LMPK04000042
inchikey: LQCLVBQBTUVCEQ-QTFUVMRISA-N
has_related_synonym: Oleandocetine
has_related_synonym: Oleandomycin triacetate
has_related_synonym: Oleandomycin triacetyl ester
database_cross_reference: PDBeChem:TAO
database_cross_reference: PMID:24335510
database_cross_reference: PMID:24479850
database_cross_reference: PMID:24889073
database_cross_reference: PMID:24985121
database_cross_reference: PMID:25392348
database_cross_reference: PMID:25870103
database_cross_reference: Reaxys:77547
has_related_synonym: Triacetyloleandomycin
has_related_synonym: Triacetyloleandomycinum
has_related_synonym: Tribiocillina
has_related_synonym: Triocetin
database_cross_reference: Wikipedia:Troleandomycin
has_obo_namespace: chebi_ontology
has_related_synonym: troleandomicina
has_related_synonym: troleandomycin
has_related_synonym: troleandomycine
has_related_synonym: troleandomycinum
in_subset: 3 STAR
imported from: chebi.owl

trifluoperazine
type: Class
subclass of: molecular entity
charge: 0
has_related_synonym: 10-[3-(4-METHYL-PIPERAZIN-1-YL)-PROPYL]-2-TRIFLUOROMETHYL-10H-PHENOTHIAZINE
has_related_synonym: 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-10H-phenothiazine
has_exact_synonym: 10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)-10H-phenothiazine
monoisotopicmass: 407.16430
mass: 407.49669
definition: A member of the class of phenothiazines that is phenothiazine having a trifluoromethyl subsitituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at the N-10 position.
database_cross_reference: Beilstein:57272
formula: C21H24F3N3S
database_cross_reference: CAS:117-89-5
has_alternative_id: CHEBI:45949
id: CHEBI:45951
has_alternative_id: CHEBI:9709
database_cross_reference: DrugBank:DB00831
database_cross_reference: Drug_Central:2740
database_cross_reference: Gmelin:2415561
database_cross_reference: HMDB:HMDB0014969
inchi: InChI=1S/C21H24F3N3S/c1-25-11-13-26(14-12-25)9-4-10-27-17-5-2-3-6-19(17)28-20-8-7-16(15-18(20)27)21(22,23)24/h2-3,5-8,15H,4,9-14H2,1H3
database_cross_reference: KEGG:C07168
database_cross_reference: KEGG:D08636
database_cross_reference: LINCS:LSM-4010
database_cross_reference: PDBeChem:TFP
database_cross_reference: PMID:11121417
database_cross_reference: PMID:14974020
database_cross_reference: PMID:15722405
database_cross_reference: PMID:1650428
database_cross_reference: PMID:19277699
database_cross_reference: PMID:19747949
database_cross_reference: PMID:20544963
database_cross_reference: PMID:7404501
database_cross_reference: PMID:9730919
database_cross_reference: Reaxys:57272
has_exact_synonym: Trifluoperazine
database_cross_reference: Wikipedia:Trifluoperazine
inchikey: ZEWQUBUPAILYHI-UHFFFAOYSA-N
has_obo_namespace: chebi_ontology
has_related_synonym: trifluoperazina
has_related_synonym: trifluoperazine
has_related_synonym: trifluoperazinum
has_related_synonym: trifluoromethyl-10-(3'-(1-methyl-4-piperazinyl)propyl)phenothiazine
has_related_synonym: trifluoroperazine
has_related_synonym: trifluperazine
in_subset: 3 STAR
imported from: chebi.owl

solvent
type: Class
subclass of: application
subclass of: chemical role
definition: A liquid that can dissolve other substances (solutes) without any change in their chemical composition.
id: CHEBI:46787
has_related_synonym: Loesungsmittel
database_cross_reference: Wikipedia:Solvent
has_obo_namespace: chebi_ontology
has_related_synonym: solvant
has_related_synonym: solvents
in_subset: 3 STAR
imported from: chebi.owl

diclofenac
type: Class
subclass of: molecular entity
charge: 0
has_related_synonym: 2-((2,6-dichlorophenyl)amino)benzeneacetic acid
has_exact_synonym: 2-[(2,6-dichlorophenyl)amino]benzeneacetic acid
monoisotopicmass: 295.01668
mass: 296.150
definition: A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
smiles: C1(Cl)=CC=CC(=C1NC2=CC=CC=C2CC(=O)O)Cl
formula: C14H11Cl2NO2
database_cross_reference: CAS:15307-86-5
has_alternative_id: CHEBI:4507
has_alternative_id: CHEBI:47380
id: CHEBI:47381
inchikey: DCOPUUMXTXDBNB-UHFFFAOYSA-N
has_exact_synonym: Diclofenac
database_cross_reference: DrugBank:DB00586
database_cross_reference: Drug_Central:865
database_cross_reference: HMDB:HMDB0014724
inchi: InChI=1S/C14H11Cl2NO2/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19/h1-7,17H,8H2,(H,18,19)
database_cross_reference: KEGG:C01690
database_cross_reference: KEGG:D07816
database_cross_reference: LINCS:LSM-2160
database_cross_reference: PDBeChem:DIF
database_cross_reference: PMID:11322639
database_cross_reference: PMID:1502708
database_cross_reference: PMID:23777257
database_cross_reference: PMID:27967303
database_cross_reference: PMID:7838674
database_cross_reference: Patent:NL6604752
database_cross_reference: Patent:US3558690
database_cross_reference: Reaxys:2146636
database_cross_reference: VSDB:1933
database_cross_reference: Wikipedia:Diclofenac
has_related_synonym: [2-(2,6-dichloroanilino)phenyl]acetic acid
has_obo_namespace: chebi_ontology
has_related_synonym: diclofenac
has_related_synonym: diclofenac acid
has_related_synonym: diclofenaco
has_related_synonym: diclofenacum
has_related_synonym: diclofenamic acid
has_exact_synonym: {2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid
in_subset: 3 STAR
imported from: chebi.owl

indicator
type: Class
subclass of: application
definition: Anything used in a scientific experiment to indicate the presence of a substance or quality, change in a body, etc.
id: CHEBI:47867
has_related_synonym: Indikator
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

photosensitizing agent
type: Class
subclass of: drug
definition: A chemical compound that can be excited by light of a specific wavelength and subsequently transfer energy to a chosen reactant. This is commonly molecular oxygen within a cancer tissue, which is converted to (highly rective) singlet state oxygen. This rapidly reacts with any nearby biomolecules, ultimately killing the cancer cells.
id: CHEBI:47868
has_obo_namespace: chebi_ontology
has_related_synonym: photosensitising agent
in_subset: 3 STAR
imported from: chebi.owl

nicotinic acetylcholine receptor agonist
type: Class
subclass of: cholinergic agonist
definition: An agonist that selectively binds to and activates a nicotinic acetylcholine receptor.
id: CHEBI:47958
has_alternative_id: CHEBI:82738
database_cross_reference: Wikipedia:Nicotinic_acetylcholine_receptor
has_obo_namespace: chebi_ontology
has_related_synonym: muscarinic agonists
has_related_synonym: nicotinic acetylcholine receptor agonists
has_related_synonym: nicotinic agonist
has_related_synonym: nicotinic agonists
in_subset: 3 STAR
imported from: chebi.owl

protein synthesis inhibitor
type: Class
subclass of: pathway inhibitor
definition: A compound, usually an anti-bacterial agent or a toxin, which inhibits the synthesis of a protein.
id: CHEBI:48001
has_obo_namespace: chebi_ontology
has_related_synonym: protein synthesis antagonist
has_related_synonym: protein synthesis antagonists
has_related_synonym: protein synthesis inhibitors
in_subset: 3 STAR
imported from: chebi.owl

antiseptic drug
type: Class
subclass of: antiinfective agent
definition: A substance used locally on humans and other animals to destroy harmful microorganisms or to inhibit their activity (cf. disinfectants, which destroy microorganisms found on non-living objects, and antibiotics, which can be transported through the lymphatic system to destroy bacteria within the body).
id: CHEBI:48218
database_cross_reference: Wikipedia:Antiseptic
has_related_synonym: antiseptic
has_related_synonym: antiseptic agent
has_related_synonym: antiseptic agents
has_related_synonym: antiseptics
has_obo_namespace: chebi_ontology
has_related_synonym: local antiinfective agents
has_related_synonym: local microbicides
has_related_synonym: topical antiinfective agents
has_related_synonym: topical microbicides
in_subset: 3 STAR
imported from: chebi.owl

disinfectant
type: Class
subclass of: antimicrobial agent
definition: An antimicrobial agent that is applied to non-living objects to destroy harmful microorganisms or to inhibit their activity.
id: CHEBI:48219
has_related_synonym: Desinfektionsmittel
has_obo_namespace: chebi_ontology
has_related_synonym: desinfectant
has_related_synonym: disinfectants
has_related_synonym: disinfecting agent
in_subset: 3 STAR
imported from: chebi.owl

serotonergic drug
type: Class
subclass of: neurotransmitter agent
id: CHEBI:48278
has_obo_namespace: chebi_ontology
has_related_synonym: serotonergic agents
has_related_synonym: serotonergic drugs
has_related_synonym: serotonin drugs
in_subset: 3 STAR
imported from: chebi.owl

serotonergic antagonist
type: Class
subclass of: serotonergic drug
has_related_synonym: 5-HT antagonists
has_related_synonym: 5-hydroxytryptamine antagonists
id: CHEBI:48279
definition: Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.
has_related_synonym: antiserotonergic agents
has_obo_namespace: chebi_ontology
has_related_synonym: serotonin antagonists
has_related_synonym: serotonin blockaders
in_subset: 3 STAR
imported from: chebi.owl

fragrance
type: Class
subclass of: application
definition: A substance, extract, or preparation for diffusing or imparting an agreeable or attractive smell.
id: CHEBI:48318
has_related_synonym: Parfuem
has_related_synonym: aroma
has_related_synonym: arome
has_obo_namespace: chebi_ontology
has_related_synonym: essence
has_related_synonym: parfum
has_related_synonym: perfume
has_related_synonym: scent
in_subset: 3 STAR
imported from: chebi.owl

serine proteinase inhibitor
type: Class
subclass of: protease inhibitor
subclass of: EC 3.4.21.* (serine endopeptidase) inhibitor
definition: An exogenous or endogenous compound which inhibits serine endopeptidases.
id: CHEBI:48353
has_obo_namespace: chebi_ontology
has_related_synonym: serine proteinase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

polar solvent
type: Class
subclass of: solvent
definition: A solvent that is composed of polar molecules. Polar solvents can dissolve ionic compounds or ionisable covalent compounds.
id: CHEBI:48354
has_obo_namespace: chebi_ontology
has_exact_synonym: polar solvent
has_related_synonym: polar solvents
in_subset: 3 STAR
imported from: chebi.owl

non-polar solvent
type: Class
subclass of: solvent
id: CHEBI:48355
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

protic solvent
type: Class
subclass of: Bronsted acid
subclass of: polar solvent
definition: A polar solvent that is capable of acting as a hydron (proton) donor.
id: CHEBI:48356
has_obo_namespace: chebi_ontology
has_exact_synonym: protogenic solvent
in_subset: 3 STAR
imported from: chebi.owl

aprotic solvent
type: Class
subclass of: solvent
id: CHEBI:48357
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

polar aprotic solvent
type: Class
subclass of: polar solvent
subclass of: aprotic solvent
definition: A solvent with a comparatively high relative permittivity (or dielectric constant), greater than ca. 15, and a sizable permanent dipole moment, that cannot donate suitably labile hydrogen atoms to form strong hydrogen bonds.
id: CHEBI:48358
has_obo_namespace: chebi_ontology
has_exact_synonym: dipolar aprotic solvent
in_subset: 3 STAR
imported from: chebi.owl

protophilic solvent
type: Class
subclass of: Bronsted base
subclass of: polar solvent
id: CHEBI:48359
has_related_synonym: HBA solvent
definition: Solvent that is capable of acting as a hydron (proton) acceptor.
has_obo_namespace: chebi_ontology
has_related_synonym: hydrogen bond acceptor solvent
has_exact_synonym: protophilic solvent
in_subset: 3 STAR
imported from: chebi.owl

amphiprotic solvent
type: Class
subclass of: protic solvent
subclass of: protophilic solvent
id: CHEBI:48360
definition: Self-ionizing solvent possessing both characteristics of Bronsted acids and bases.
has_exact_synonym: amphiprotic solvent
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 2.1.1.6 (catechol O-methyltransferase) inhibitor
type: Class
subclass of: EC 2.1.1.* (methyltransferases) inhibitor
definition: An EC 2.1.1.* (methyltransferase) inhibitor that interferes with the action of catechol O-methyltransferase (EC 2.1.1.6).
id: CHEBI:48406
has_related_synonym: COMT inhibitor
has_related_synonym: COMT inhibitors
has_related_synonym: EC 2.1.1.6 (catechol O-methyltransferase) inhibitors
has_related_synonym: EC 2.1.1.6 inhibitor
has_related_synonym: EC 2.1.1.6 inhibitors
has_related_synonym: S-adenosyl-L-methionine:catechol O-methyltransferase inhibitor
has_related_synonym: S-adenosyl-L-methionine:catechol O-methyltransferase inhibitors
database_cross_reference: Wikipedia:Catechol_O-methyltransferase
has_related_synonym: catechol O-methyltransferase (EC 2.1.1.6) inhibitor
has_related_synonym: catechol O-methyltransferase (EC 2.1.1.6) inhibitors
has_related_synonym: catechol O-methyltransferase inhibitor
has_related_synonym: catechol O-methyltransferase inhibitors
has_related_synonym: catechol methyltransferase inhibitor
has_related_synonym: catechol methyltransferase inhibitors
has_related_synonym: catecholamine O-methyltransferase inhibitor
has_related_synonym: catecholamine O-methyltransferase inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

antiparkinson drug
type: Class
subclass of: antidyskinesia agent
definition: A drug used in the treatment of Parkinson's disease.
id: CHEBI:48407
database_cross_reference: Wikipedia:Antiparkinson
has_related_synonym: antiparkinson agent
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

angiogenesis inhibitor
type: Class
subclass of: drug
definition: An agent and endogenous substances that antagonize or inhibit the development of new blood vessels.
id: CHEBI:48422
has_alternative_id: CHEBI:67170
database_cross_reference: Wikipedia:Angiogenesis_inhibitor
has_related_synonym: angiogenesis antagonist
has_related_synonym: angiostatic agents
has_related_synonym: anti-angiogenic agent
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

topical anaesthetic
type: Class
subclass of: local anaesthetic
definition: A local anesthetic that is used to numb the surface of a body part.
id: CHEBI:48425
has_obo_namespace: chebi_ontology
has_related_synonym: topical anaesthetics
has_related_synonym: topical anesthetic
in_subset: 3 STAR
imported from: chebi.owl

calcimimetic
type: Class
subclass of: drug
definition: A drug that it mimics the action of calcium on tissues.
id: CHEBI:48525
has_related_synonym: calcimimetics
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

alpha-adrenergic drug
type: Class
subclass of: adrenergic agent
definition: Any drug that acts on an alpha-adrenergic receptor.
id: CHEBI:48539
has_related_synonym: alpha-adrenergic drugs
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

beta-adrenergic drug
type: Class
subclass of: adrenergic agent
definition: Any of the drugs that act on beta-adrenergic receptors.
id: CHEBI:48540
has_related_synonym: beta-adrenergic drugs
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 1.1.1.21 (aldehyde reductase) inhibitor
type: Class
subclass of: EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor
has_related_synonym: ALR2 inhibitor
has_related_synonym: ALR2 inhibitors
definition: An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of aldehyde reductase (EC 1.1.1.21).
id: CHEBI:48550
has_related_synonym: EC 1.1.1.21 (aldehyde reductase) inhibitors
has_related_synonym: EC 1.1.1.21 inhibitor
has_related_synonym: EC 1.1.1.21 inhibitors
has_related_synonym: NADPH-aldopentose reductase inhibitor
has_related_synonym: NADPH-aldopentose reductase inhibitors
has_related_synonym: NADPH-aldose reductase inhibitor
has_related_synonym: NADPH-aldose reductase inhibitors
has_related_synonym: aldehyde reductase (EC 1.1.1.21) inhibitor
has_related_synonym: aldehyde reductase (EC 1.1.1.21) inhibitors
has_related_synonym: aldehyde reductase inhibitor
has_related_synonym: aldehyde reductase inhibitors
has_related_synonym: alditol:NAD(P)(+) 1-oxidoreductase inhibitor
has_related_synonym: alditol:NAD(P)(+) 1-oxidoreductase inhibitors
has_related_synonym: alditol:NADP oxidoreductase inhibitor
has_related_synonym: alditol:NADP oxidoreductase inhibitors
has_related_synonym: alditol:NADP(+) 1-oxidoreductase inhibitor
has_related_synonym: alditol:NADP(+) 1-oxidoreductase inhibitors
has_related_synonym: aldose reductase inhibitor
has_related_synonym: aldose reductase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: polyol dehydrogenase (NADP(+)) inhibitor
has_related_synonym: polyol dehydrogenase (NADP(+)) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

dopaminergic agent
type: Class
subclass of: neurotransmitter agent
definition: A drug used for its effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons.
id: CHEBI:48560
has_obo_namespace: chebi_ontology
has_related_synonym: dopamine agent
has_related_synonym: dopamine agents
has_related_synonym: dopamine drug
has_related_synonym: dopamine drugs
has_related_synonym: dopaminergic agents
in_subset: 3 STAR
imported from: chebi.owl

dopaminergic antagonist
type: Class
subclass of: dopaminergic agent
subclass of: antagonist
definition: A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
id: CHEBI:48561
has_obo_namespace: chebi_ontology
has_related_synonym: dopamine antagonist
has_related_synonym: dopamine blocker
has_related_synonym: dopamine receptor antagonist
has_related_synonym: dopaminergic antagonists
in_subset: 3 STAR
imported from: chebi.owl

radical scavenger
type: Class
subclass of: antioxidant
definition: A role played by a substance that can react readily with, and thereby eliminate, radicals.
id: CHEBI:48578
has_obo_namespace: chebi_ontology
has_related_synonym: free radical scavengers
has_related_synonym: free-radical scavenger
in_subset: 3 STAR
imported from: chebi.owl

gamma-secretase modulator
type: Class
subclass of: effector
definition: A modulator of gamma-secretase, one of the three endopeptidases that are specific for amyloid protein precursor and which have been identified based upon the region of the amyloid protein precursor which they cleave.
id: CHEBI:48668
has_exact_synonym: Gamma-secretase modulator
has_related_synonym: Gamma-secretase modulators
database_cross_reference: Wikipedia:Gamma_secretase
has_obo_namespace: chebi_ontology
has_related_synonym: gamma secretase modulator
has_related_synonym: gamma secretase modulators
has_exact_synonym: gamma-secretase modulator
has_related_synonym: gamma-secretase modulators
in_subset: 3 STAR
imported from: chebi.owl

antifibrinolytic drug
type: Class
subclass of: fibrin modulating drug
definition: A drug that prevent fibrinolysis or lysis of a blood clot or thrombus.
id: CHEBI:48675
has_related_synonym: antifibrinolytic agent
has_related_synonym: antifibrinolytic agents
has_related_synonym: antifibrinolytic drugs
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

fibrin modulating drug
type: Class
subclass of: drug
definition: A drug that affects the function of fibrin in blood coagulation.
id: CHEBI:48676
has_obo_namespace: chebi_ontology
has_related_synonym: fibrin modulating agent
has_related_synonym: fibrin modulating agents
has_related_synonym: fibrin modulating drugs
in_subset: 3 STAR
imported from: chebi.owl

agonist
type: Class
subclass of: pharmacological role
id: CHEBI:48705
definition: Substance which binds to cell receptors normally responding to naturally occurring substances and which produces a response of its own.
has_exact_synonym: agonist
has_related_synonym: agonista
has_related_synonym: agoniste
has_related_synonym: agonists
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

antagonist
type: Class
subclass of: pharmacological role
id: CHEBI:48706
definition: Substance that attaches to and blocks cell receptors that normally bind naturally occurring substances.
has_exact_synonym: antagonist
has_related_synonym: antagonista
has_related_synonym: antagoniste
has_related_synonym: antagonists
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

estropipate
type: Class
subclass of: molecular entity
charge: 0
monoisotopicmass: 436.20319
mass: 436.567
formula: C18H22O5S.C4H10N2
formula: C22H32N2O5S
database_cross_reference: CAS:7280-37-7
id: CHEBI:4873
has_exact_synonym: Estropipate
inchikey: HZEQBCVBILBTEP-ZFINNJDLSA-N
inchi: InChI=1S/C18H22O5S.C4H10N2/c1-18-9-8-14-13-5-3-12(23-24(20,21)22)10-11(13)2-4-15(14)16(18)6-7-17(18)19;1-2-6-4-3-5-1/h3,5,10,14-16H,2,4,6-9H2,1H3,(H,20,21,22);5-6H,1-4H2/t14-,15-,16+,18+;/m1./s1
database_cross_reference: KEGG:D00948
has_related_synonym: Piperazine estrone sulfate
has_obo_namespace: chebi_ontology
in_subset: 2 STAR
imported from: chebi.owl

cholinergic antagonist
type: Class
subclass of: cholinergic drug
has_related_synonym: Anticholinergika
has_related_synonym: Anticholinergikum
definition: Any drug that binds to but does not activate cholinergic receptors, thereby blocking the actions of acetylcholine or cholinergic agonists.
id: CHEBI:48873
has_related_synonym: acetylcholine antagonists
has_related_synonym: acetylcholine receptor antagonist
has_related_synonym: agent anticholinergique
has_related_synonym: agente anticolinergico
has_related_synonym: agentes anticolinergicos
has_related_synonym: anticholinergic agents
has_related_synonym: anticholinergics
has_related_synonym: anticholinergiques
has_related_synonym: anticolinergicos
has_obo_namespace: chebi_ontology
has_related_synonym: cholinergic-blocking agents
in_subset: 3 STAR
imported from: chebi.owl

muscarinic antagonist
type: Class
subclass of: cholinergic antagonist
definition: A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
has_related_synonym: Antimuskarinika
has_related_synonym: Antimuskarinikum
id: CHEBI:48876
has_related_synonym: agente antimuscarinico
has_related_synonym: agentes antimuscarinicos
has_related_synonym: agents antimuscariniques
has_related_synonym: antimuscarinic agents
has_related_synonym: antimuscarinicos
has_obo_namespace: chebi_ontology
has_related_synonym: muscarinic acetylcholine receptor antagonist
has_related_synonym: muscarinic antagonists
in_subset: 3 STAR
imported from: chebi.owl

nicotinic antagonist
type: Class
subclass of: cholinergic antagonist
definition: An antagonist at the nicotinic cholinergic receptor.
id: CHEBI:48878
database_cross_reference: Wikipedia:Nicotinic_antagonist
has_related_synonym: agente antinicotinico
has_related_synonym: agentes antinicotinicos
has_related_synonym: agents antinicotiniques
has_related_synonym: antinicotinicos
has_obo_namespace: chebi_ontology
has_related_synonym: nicotinic acetylcholine receptor antagonist
has_related_synonym: nicotinic acetylcholine receptor antagonists
has_related_synonym: nicotinic antagonists
has_related_synonym: nicotinic cholinergic antagonist
has_related_synonym: nicotinic cholinergic antagonists
in_subset: 3 STAR
imported from: chebi.owl

bile acid metabolite
type: Class
subclass of: metabolite
id: CHEBI:48887
definition: Metabolites of bile acids, four-ringed steroid acids formed along the cholesterol degradation pathway.
has_related_synonym: bile acid metabolites
has_related_synonym: bile salt metabolite
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

hormone antagonist
type: Class
subclass of: antagonist
subclass of: hormone receptor modulator
definition: A chemical substance which inhibits the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites.
id: CHEBI:49020
has_obo_namespace: chebi_ontology
has_related_synonym: hormone antagonists
in_subset: 3 STAR
imported from: chebi.owl

prostaglandin antagonist
type: Class
subclass of: hormone antagonist
definition: A compound that inhibits the action of prostaglandins.
id: CHEBI:49023
database_cross_reference: Wikipedia:Prostaglandin_antagonist
has_obo_namespace: chebi_ontology
has_related_synonym: prostaglandin inhibitor
in_subset: 3 STAR
imported from: chebi.owl

drug metabolite
type: Class
subclass of: human xenobiotic metabolite
id: CHEBI:49103
has_obo_namespace: chebi_ontology
has_related_synonym: drug metabolites
in_subset: 3 STAR
imported from: chebi.owl

peripheral nervous system drug
type: Class
subclass of: drug
definition: A drug that acts principally at one or more sites within the peripheral neuroeffector systems, the autonomic system, and motor nerve-skeletal system.
id: CHEBI:49110
has_obo_namespace: chebi_ontology
has_related_synonym: peripheral nervous system agent
has_related_synonym: peripheral nervous system drugs
in_subset: 3 STAR
imported from: chebi.owl

leukotriene antagonist
type: Class
subclass of: hormone antagonist
definition: A drug designed to prevent leukotriene synthesis or activity by blocking binding at the receptor level.
id: CHEBI:49159
has_related_synonym: LTRA
has_obo_namespace: chebi_ontology
has_related_synonym: leukotriene antagonists
has_related_synonym: leukotriene receptor antagonist
has_related_synonym: leukotriene receptor antagonists
in_subset: 3 STAR
imported from: chebi.owl

anti-asthmatic drug
type: Class
subclass of: drug
subclass of: anti-asthmatic agent
definition: A drug used to treat asthma.
id: CHEBI:49167
has_related_synonym: anti-asthmatic agent
has_related_synonym: anti-asthmatic agents
has_related_synonym: anti-asthmatic drugs
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor
type: Class
subclass of: EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor
has_related_synonym: (K(+) + H(+))-ATPase inhibitor
has_related_synonym: (K(+) + H(+))-ATPase inhibitors
has_related_synonym: ATP phosphohydrolase (H(+)/K(+)-exchanging) inhibitor
has_related_synonym: ATP phosphohydrolase (H(+)/K(+)-exchanging) inhibitors
definition: An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that inhibits H(+)/K(+)-exchanging ATPase, EC 3.6.3.10. Such compounds are also known as proton pump inhibitors.
id: CHEBI:49200
has_related_synonym: EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitors
has_related_synonym: EC 3.6.3.10 inhibitor
has_related_synonym: EC 3.6.3.10 inhibitors
has_related_synonym: H(+)-K(+)-ATPase inhibitor
has_related_synonym: H(+)-K(+)-ATPase inhibitors
has_related_synonym: H(+)/K(+)-ATPase inhibitor
has_related_synonym: H(+)/K(+)-ATPase inhibitors
has_related_synonym: H(+)/K(+)-exchanging ATPase inhibitor
has_related_synonym: H(+)/K(+)-exchanging ATPase inhibitors
has_related_synonym: H,K-ATPase inhibitor
has_related_synonym: H,K-ATPase inhibitors
database_cross_reference: Wikipedia:Proton_pump_inhibitor
has_obo_namespace: chebi_ontology
has_related_synonym: proton pump inhibitor
has_related_synonym: proton pump inhibitors
in_subset: 3 STAR
imported from: chebi.owl

anti-ulcer drug
type: Class
subclass of: drug
id: CHEBI:49201
definition: One of various classes of drugs with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract.
has_related_synonym: anti-ulcer agent
has_related_synonym: anti-ulcer agents
has_related_synonym: anti-ulcer drugs
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

CETP inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
definition: Any inhibitor of cholesterylester transfer protein (CETP), which transfers cholesterol from high density lipoproteins (HDL, the 'good' cholesterol-containing particles) to low or very low density lipoproteins (LDL or VLDL, the 'bad' cholesterol-containing particles). Inhibition of this process results in higher HDL levels and lower LDL levels. CETP inhibitors are under investigation as potential drugs to reduce the risk of arteriosclerotic vascular disease (atherosclerosis).
has_related_synonym: CETP inhibitors
id: CHEBI:49205
database_cross_reference: Wikipedia:CETP_inhibitor
has_obo_namespace: chebi_ontology
has_related_synonym: cholesteryl ester transfer protein inhibitor
in_subset: 3 STAR
imported from: chebi.owl

contraceptive drug
type: Class
subclass of: reproductive control drug
definition: A chemical substance that prevents or reduces the probability of conception.
id: CHEBI:49323
has_obo_namespace: chebi_ontology
has_related_synonym: contraceptive agent
has_related_synonym: contraceptive drugs
in_subset: 3 STAR
imported from: chebi.owl

female contraceptive drug
type: Class
subclass of: contraceptive drug
definition: A chemical substance or agent with contraceptive activity in females.
id: CHEBI:49324
has_obo_namespace: chebi_ontology
has_related_synonym: female contraceptive agent
has_related_synonym: female contraceptive drugs
in_subset: 3 STAR
imported from: chebi.owl

oral contraceptive
type: Class
subclass of: female contraceptive drug
definition: A compound, usually hormonal, taken orally in order to block ovulation and prevent the occurrence of pregnancy.
id: CHEBI:49325
has_obo_namespace: chebi_ontology
has_related_synonym: oral contraceptives
in_subset: 3 STAR
imported from: chebi.owl

synthetic oral contraceptive
type: Class
subclass of: oral contraceptive
definition: An oral contraceptive which owes its effectiveness to synthetic preparation.
id: CHEBI:49326
has_obo_namespace: chebi_ontology
has_related_synonym: synthetic oral contraceptives
in_subset: 3 STAR
imported from: chebi.owl

excitatory amino acid agonist
type: Class
subclass of: neurotransmitter agent
definition: An agent that binds to and activates excitatory amino acid receptors.
id: CHEBI:50103
has_obo_namespace: chebi_ontology
has_related_synonym: excitatory amino acid agonists
has_related_synonym: excitatory amino acid receptor agonist
has_related_synonym: excitatory amino acid receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

sex hormone
type: Class
subclass of: hormone
definition: Any hormone that is responsible for controlling sexual characteristics and reproductive function.
id: CHEBI:50112
has_related_synonym: Geschlechtshormon
has_related_synonym: Geschlechtshormone
has_related_synonym: Sexualhormon
has_related_synonym: Sexualhormone
has_obo_namespace: chebi_ontology
has_related_synonym: hormone sexuelle
has_related_synonym: hormones sexuelles
has_related_synonym: sex hormones
in_subset: 3 STAR
imported from: chebi.owl

androgen
type: Class
subclass of: sex hormone
definition: A sex hormone that stimulates or controls the development and maintenance of masculine characteristics in vertebrates by binding to androgen receptors.
has_exact_synonym: Androgen
has_related_synonym: Androgene
id: CHEBI:50113
has_related_synonym: androgene
has_related_synonym: androgenes
has_related_synonym: androgeno
has_related_synonym: androgenos
has_related_synonym: androgens
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

estrogen
type: Class
subclass of: sex hormone
definition: A hormone that stimulates or controls the development and maintenance of female sex characteristics in mammals by binding to oestrogen receptors. The oestrogens are named for their importance in the oestrous cycle. The oestrogens that occur naturally in the body, notably estrone, estradiol, estriol, and estetrol are steroids. Other compounds with oestrogenic activity are produced by plants (phytoestrogens) and fungi (mycoestrogens); synthetic compounds with oestrogenic activity are known as xenoestrogens.
id: CHEBI:50114
has_related_synonym: Estrogene
has_related_synonym: Oestrogen
has_related_synonym: Oestrogene
database_cross_reference: Wikipedia:Estrogen
has_obo_namespace: chebi_ontology
has_related_synonym: estrogene
has_related_synonym: estrogenes
has_related_synonym: estrogenes Hormon
has_related_synonym: estrogeno
has_related_synonym: estrogenos
has_related_synonym: estrogens
has_related_synonym: oestrogen
has_related_synonym: oestrogene
has_related_synonym: oestrogenes
has_related_synonym: oestrogens
in_subset: 3 STAR
imported from: chebi.owl

mu-opioid receptor antagonist
type: Class
subclass of: mu-opioid agent
subclass of: opioid receptor antagonist
definition: Any compound that exhibits antagonist activity at the mu-opioid receptor
id: CHEBI:50137
has_obo_namespace: chebi_ontology
has_related_synonym: mu-opioid antagonist
has_related_synonym: mu-opioid antagonists
has_related_synonym: mu-opioid receptor antagonists
in_subset: 3 STAR
imported from: chebi.owl

bronchoconstrictor agent
type: Class
subclass of: drug
definition: A drug which causes a narrowing of the lumen of a bronchus or bronchiole.
id: CHEBI:50141
has_related_synonym: bronchoconstrictor agents
has_related_synonym: bronchoconstrictor drug
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

keratolytic drug
type: Class
subclass of: dermatologic drug
definition: A drug that softens, separates, and causes desquamation of the cornified epithelium or horny layer of skin. Keratolytic drugs are used to expose mycelia of infecting fungi or to treat corns, warts, and certain other skin diseases.
id: CHEBI:50176
has_obo_namespace: chebi_ontology
has_related_synonym: desquamating agent
has_related_synonym: keratolytic agent
has_related_synonym: keratolytic drugs
has_related_synonym: skin-peeling agent
in_subset: 3 STAR
imported from: chebi.owl

dermatologic drug
type: Class
subclass of: drug
definition: A drug used to treat or prevent skin disorders or for the routine care of skin.
id: CHEBI:50177
has_obo_namespace: chebi_ontology
has_related_synonym: dermatologic agent
has_related_synonym: dermatologic drugs
has_related_synonym: dermatological agent
in_subset: 3 STAR
imported from: chebi.owl

P450 inhibitor
type: Class
subclass of: EC 1.14.14.1 (unspecific monooxygenase) inhibitor
definition: An enzyme inhibitor that interferes with the activity of cytochrome P450 involved in catalysis of organic substances.
id: CHEBI:50183
has_related_synonym: CYP2D6 inhibitor
has_related_synonym: CYP2D6 inhibitors
has_related_synonym: P450 inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: cytochrome P450 inhibitor
has_related_synonym: cytochrome P450 inhibitors
in_subset: 3 STAR
imported from: chebi.owl

ion transport inhibitor
type: Class
subclass of: membrane transport modulator
definition: A compound which inhibits the movement of an ion across an energy-transducing cell membrane.
id: CHEBI:50184
has_obo_namespace: chebi_ontology
has_related_synonym: ion transport inhibitors
has_related_synonym: ion-transport inhibitor
has_related_synonym: ion-transport inhibitors
in_subset: 3 STAR
imported from: chebi.owl

fatty acid synthesis inhibitor
type: Class
subclass of: pathway inhibitor
definition: Any pathway inhibitor that inhibits the synthesis of fatty acids.
id: CHEBI:50185
has_obo_namespace: chebi_ontology
has_related_synonym: fatty acid synthesis inhibitors
in_subset: 3 STAR
imported from: chebi.owl

provitamin
type: Class
subclass of: biological role
definition: A substance that can be converted into a vitamin by animal tissues.
id: CHEBI:50188
database_cross_reference: Wikipedia:Provitamin
has_obo_namespace: chebi_ontology
has_related_synonym: provitamins
in_subset: 3 STAR
imported from: chebi.owl

EC 3.1.4.* (phosphoric diester hydrolase) inhibitor
type: Class
subclass of: EC 3.1.* (ester hydrolase) inhibitor
definition: An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of a phosphoric diester hydrolase (EC 3.1.4.*).
id: CHEBI:50218
has_alternative_id: CHEBI:76774
has_related_synonym: EC 3.1.4.* (phosphoric diester hydrolase) inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: phosphodiesterase inhibitor
has_related_synonym: phosphodiesterase inhibitors
has_related_synonym: phosphoric diester hydrolase (EC 3.1.4.*) inhibitor
has_related_synonym: phosphoric diester hydrolase (EC 3.1.4.*) inhibitors
has_related_synonym: phosphoric diester hydrolase inhibitor
has_related_synonym: phosphoric diester hydrolase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

cholinesterase reactivator
type: Class
subclass of: enzyme reactivator
definition: A drug used to reverse the inactivation of cholinesterase caused by organophosphates or sulfonates.
id: CHEBI:50241
has_obo_namespace: chebi_ontology
has_related_synonym: cholinesterase reactivators
in_subset: 3 STAR
imported from: chebi.owl

enzyme reactivator
type: Class
subclass of: biochemical role
id: CHEBI:50242
definition: Compound which restore enzymatic activity by removing an inhibitory group bound to the reactive site of the enzyme.
database_cross_reference: PMID:15551381
database_cross_reference: PMID:16763789
database_cross_reference: PMID:8415873
has_obo_namespace: chebi_ontology
has_related_synonym: enzyme reactivators
in_subset: 3 STAR
imported from: chebi.owl

antidote
type: Class
subclass of: protective agent
definition: Any protective agent counteracting or neutralizing the action of poisons.
id: CHEBI:50247
has_related_synonym: antidotes
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

hematologic agent
type: Class
subclass of: drug
id: CHEBI:50248
definition: Drug that acts on blood and blood-forming organs and those that affect the hemostatic system.
has_obo_namespace: chebi_ontology
has_related_synonym: hematologic agents
in_subset: 3 STAR
imported from: chebi.owl

anticoagulant
type: Class
subclass of: hematologic agent
definition: An agent that prevents blood clotting.
id: CHEBI:50249
has_related_synonym: anticoagulante
has_related_synonym: anticoagulants
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

prodrug
type: Class
subclass of: pro-agent
subclass of: drug
definition: A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.
id: CHEBI:50266
database_cross_reference: PMID:23993918
database_cross_reference: PMID:23998799
database_cross_reference: PMID:24329110
database_cross_reference: PMID:24628402
database_cross_reference: PMID:24709544
database_cross_reference: PMID:25144792
database_cross_reference: PMID:25157234
database_cross_reference: PMID:25269430
database_cross_reference: PMID:25391982
database_cross_reference: PMID:25591121
database_cross_reference: PMID:25620096
database_cross_reference: PMID:25795057
database_cross_reference: PMID:26028253
database_cross_reference: PMID:26184144
database_cross_reference: PMID:28070577
database_cross_reference: PMID:28215138
database_cross_reference: PMID:28219047
database_cross_reference: PMID:28259775
database_cross_reference: PMID:28319647
database_cross_reference: PMID:28329729
database_cross_reference: PMID:28334528
has_related_synonym: Prodrugs
database_cross_reference: Wikipedia:Prodrug
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

protective agent
type: Class
subclass of: drug
id: CHEBI:50267
definition: Synthetic or natural substance which is given to prevent a disease or disorder or are used in the process of treating a disease or injury due to a poisonous agent.
has_obo_namespace: chebi_ontology
has_related_synonym: chemoprotectant
has_related_synonym: chemoprotectants
has_related_synonym: chemoprotective agent
has_related_synonym: chemoprotective agents
has_related_synonym: protective agents
in_subset: 3 STAR
imported from: chebi.owl

GABA modulator
type: Class
subclass of: membrane transport modulator
subclass of: GABA agent
definition: A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
id: CHEBI:50268
has_related_synonym: GABA modulators
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 1.1.1.1 (alcohol dehydrogenase) inhibitor
type: Class
subclass of: EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor
has_related_synonym: ADH inhibitor
has_related_synonym: ADH inhibitors
definition: An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of alcohol dehydrogenase (EC 1.1.1.1).
id: CHEBI:50269
has_related_synonym: EC 1.1.1.1 (alcohol dehydrogenase) inhibitors
has_related_synonym: EC 1.1.1.1 inhibitor
has_related_synonym: EC 1.1.1.1 inhibitors
has_related_synonym: NAD-dependent alcohol dehydrogenase inhibitor
has_related_synonym: NAD-dependent alcohol dehydrogenase inhibitors
has_related_synonym: NAD-specific aromatic alcohol dehydrogenase inhibitor
has_related_synonym: NAD-specific aromatic alcohol dehydrogenase inhibitors
has_related_synonym: NADH-alcohol dehydrogenase inhibitor
has_related_synonym: NADH-alcohol dehydrogenase inhibitors
has_related_synonym: NADH-aldehyde dehydrogenase inhibitor
has_related_synonym: NADH-aldehyde dehydrogenase inhibitors
database_cross_reference: Wikipedia:Alcohol_dehydrogenase
has_related_synonym: alcohol dehydrogenase (EC 1.1.1.1) inhibitor
has_related_synonym: alcohol dehydrogenase (EC 1.1.1.1) inhibitors
has_related_synonym: alcohol dehydrogenase (NAD) inhibitor
has_related_synonym: alcohol dehydrogenase (NAD) inhibitors
has_related_synonym: alcohol dehydrogenase inhibitor
has_related_synonym: alcohol dehydrogenase inhibitors
has_related_synonym: alcohol:NAD+ oxidoreductase inhibitor
has_related_synonym: alcohol:NAD+ oxidoreductase inhibitors
has_related_synonym: aldehyde reductase inhibitor
has_related_synonym: aldehyde reductase inhibitors
has_related_synonym: aliphatic alcohol dehydrogenase inhibitor
has_related_synonym: aliphatic alcohol dehydrogenase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: ethanol dehydrogenase inhibitor
has_related_synonym: ethanol dehydrogenase inhibitors
has_related_synonym: primary alcohol dehydrogenase inhibitor
has_related_synonym: primary alcohol dehydrogenase inhibitors
has_related_synonym: yeast alcohol dehydrogenase inhibitor
has_related_synonym: yeast alcohol dehydrogenase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

esomeprazole
type: Class
subclass of: molecular entity
has_related_synonym: (-)-omeprazole
has_related_synonym: (S)-(-)-omeprazole
has_related_synonym: (S)-omeprazole
charge: 0
monoisotopicmass: 345.11471
mass: 345.41600
has_exact_synonym: 5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole
definition: A 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole that has S configuration at the sulfur atom. An inhibitor of gastric acid secretion, it is used (generally as its sodium or magnesium salt) for the treatment of gastro-oesophageal reflux disease, dyspepsia, peptic ulcer disease, and Zollinger-Ellison syndrome.
has_related_synonym: Alenia
formula: C17H19N3O3S
database_cross_reference: CAS:119141-88-7
id: CHEBI:50275
database_cross_reference: DrugBank:DB00736
database_cross_reference: Drug_Central:1055
has_related_synonym: Escz
has_related_synonym: Esofag
database_cross_reference: HMDB:HMDB0005009
database_cross_reference: HMDB:HMDB0014874
inchi: InChI=1S/C17H19N3O3S/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20)/t24-/m0/s1
has_related_synonym: Inexium paranova
database_cross_reference: KEGG:D07917
database_cross_reference: PMID:10983736
database_cross_reference: PMID:15080761
database_cross_reference: PMID:18407713
database_cross_reference: PMID:18472988
database_cross_reference: PMID:23677700
database_cross_reference: Reaxys:12060639
inchikey: SUBDBMMJDZJVOS-DEOSSOPVSA-N
database_cross_reference: Wikipedia:Esomeprazole
has_obo_namespace: chebi_ontology
has_related_synonym: esomeprazol
has_related_synonym: esomeprazole
has_related_synonym: esomeprazolum
in_subset: 3 STAR
imported from: chebi.owl

EC 5.99.1.2 (DNA topoisomerase) inhibitor
type: Class
subclass of: topoisomerase inhibitor
definition: A topoisomerase inhibitor that inhibits the bacterial enzymes of the DNA topoisomerases, Type I class (EC 5.99.1.2) that catalyze ATP-independent breakage of one of the two strands of DNA, passage of the unbroken strand through the break, and rejoining of the broken strand. These bacterial enzymes reduce the topological stress in the DNA structure by relaxing negatively, but not positively, supercoiled DNA.
id: CHEBI:50276
has_related_synonym: DNA topoisomerase inhibitor
has_related_synonym: DNA topoisomerase inhibitors
has_related_synonym: EC 5.99.1.2 (DNA topoisomerase) inhibitors
has_related_synonym: EC 5.99.1.2 (topoisomerase I) inhibitor
has_related_synonym: EC 5.99.1.2 (topoisomerase I) inhibitors
has_related_synonym: EC 5.99.1.2 inhibitor
has_related_synonym: EC 5.99.1.2 inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: topoisomerase I (EC 5.99.1.2) inhibitor
has_related_synonym: topoisomerase I (EC 5.99.1.2) inhibitors
has_related_synonym: topoisomerase I inhibitor
has_related_synonym: topoisomerase I inhibitors
has_related_synonym: type I DNA topoisomerase inhibitor
has_related_synonym: type I DNA topoisomerase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

parasympatholytic
type: Class
subclass of: cholinergic antagonist
definition: Any cholinergic antagonist that inhibits the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the muscarinic antagonists.
id: CHEBI:50370
has_obo_namespace: chebi_ontology
has_related_synonym: parasympatholytics
in_subset: 3 STAR
imported from: chebi.owl

EC 2.4.1.80 (ceramide glucosyltransferase) inhibitor
type: Class
subclass of: EC 2.4.1.* (hexosyltransferase) inhibitor
definition: An EC 2.4.1.* (hexosyltransferase) inhibitor that interferes with the activity of ceramide glucosyltransferase (EC 2.4.1.80).
id: CHEBI:50382
has_alternative_id: CHEBI:75128
has_related_synonym: EC 2.4.1.80 (ceramide glucosyltransferase) inhibitors
has_related_synonym: EC 2.4.1.80 inhibitor
has_related_synonym: EC 2.4.1.80 inhibitors
database_cross_reference: PMID:19285492
database_cross_reference: PMID:21974949
database_cross_reference: PMID:22918683
has_related_synonym: UDP-glucose:N-acylsphingosine D-glucosyltransferase inhibitor
has_related_synonym: UDP-glucose:N-acylsphingosine D-glucosyltransferase inhibitors
has_related_synonym: UDP-glucose:ceramide glucosyltransferase inhibitor
has_related_synonym: UDP-glucose:ceramide glucosyltransferase inhibitors
database_cross_reference: Wikipedia:Ceramide_glucosyltransferase
has_related_synonym: ceramide glucosyltransferase (EC 2.4.1.80) inhibitor
has_related_synonym: ceramide glucosyltransferase (EC 2.4.1.80) inhibitors
has_related_synonym: ceramide glucosyltransferase inhibitor
has_related_synonym: ceramide glucosyltransferase inhibitors
has_related_synonym: ceramide:UDP-glucose glucosyltransferase inhibitor
has_related_synonym: ceramide:UDP-glucose glucosyltransferase inhibitors
has_related_synonym: ceramide:UDPGlc glucosyltransferase inhibitor
has_related_synonym: ceramide:UDPGlc glucosyltransferase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: glucosylceramide synthase inhibitor
has_related_synonym: glucosylceramide synthase inhibitors
has_related_synonym: uridine diphosphoglucose-ceramide glucosyltransferase inhibitor
has_related_synonym: uridine diphosphoglucose-ceramide glucosyltransferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor
type: Class
subclass of: EC 1.6.5.* (oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor) inhibitor
definition: An EC 1.6.5.* (oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor) inhibitor that interferes with the action of NAD(P)H dehydrogenase (quinone), EC 1.6.5.2.
id: CHEBI:50390
has_related_synonym: DT diaphorase inhibitor
has_related_synonym: EC 1.6.5.2 (NAD(P)H dehydrogenase (quinone)) inhibitor
has_related_synonym: EC 1.6.5.2 (NAD(P)H dehydrogenase (quinone)) inhibitors
has_related_synonym: EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitors
has_related_synonym: EC 1.6.5.2 inhibitor
has_related_synonym: EC 1.6.5.2 inhibitors
has_related_synonym: NAD(P)H dehydrogenase (quinone) (EC 1.6.5.2) inhibitor
has_related_synonym: NAD(P)H dehydrogenase (quinone) (EC 1.6.5.2) inhibitors
has_related_synonym: NAD(P)H dehydrogenase (quinone) inhibitor
has_related_synonym: NAD(P)H dehydrogenase (quinone) inhibitors
has_related_synonym: NAD(P)H dehydrogenase inhibitor
has_related_synonym: NAD(P)H dehydrogenase inhibitors
has_related_synonym: NAD(P)H menadione reductase inhibitor
has_related_synonym: NAD(P)H menadione reductase inhibitors
has_related_synonym: NAD(P)H-quinone dehydrogenase inhibitor
has_related_synonym: NAD(P)H-quinone dehydrogenase inhibitors
has_related_synonym: NAD(P)H-quinone oxidoreductase inhibitor
has_related_synonym: NAD(P)H-quinone oxidoreductase inhibitors
has_related_synonym: NAD(P)H2 dehydrogenase (quinone) inhibitor
has_related_synonym: NAD(P)H2 dehydrogenase (quinone) inhibitors
has_related_synonym: NAD(P)H: menadione oxidoreductase inhibitor
has_related_synonym: NAD(P)H: menadione oxidoreductase inhibitors
has_related_synonym: NAD(P)H:(quinone-acceptor)oxidoreductase inhibitor
has_related_synonym: NAD(P)H:(quinone-acceptor)oxidoreductase inhibitors
has_related_synonym: NAD(P)H:quinone oxidoreductase inhibitor
has_related_synonym: NAD(P)H:quinone oxidoreductase inhibitors
has_related_synonym: NADH-menadione reductase inhibitor
has_related_synonym: NADH-menadione reductase inhibitors
has_related_synonym: NQO1 inhibitor
has_related_synonym: NQO1 inhibitors
has_related_synonym: QR1 inhibitor
has_related_synonym: QR1 inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: dehydrogenase, reduced nicotinamide adenine dinucleotide (phosphate, quinone) inhibitor
has_related_synonym: dehydrogenase, reduced nicotinamide adenine dinucleotide (phosphate, quinone) inhibitors
has_related_synonym: diaphorase inhibitor
has_related_synonym: diaphorase inhibitors
has_related_synonym: flavoprotein NAD(P)H-quinone reductase inhibitor
has_related_synonym: flavoprotein NAD(P)H-quinone reductase inhibitors
has_related_synonym: menadione oxidoreductase inhibitor
has_related_synonym: menadione oxidoreductase inhibitors
has_related_synonym: menadione reductase inhibitor
has_related_synonym: menadione reductase inhibitors
has_related_synonym: naphthoquinone reductase inhibitor
has_related_synonym: naphthoquinone reductase inhibitors
has_related_synonym: p-benzoquinone reductase inhibitor
has_related_synonym: p-benzoquinone reductase inhibitors
has_related_synonym: phylloquinone reductase inhibitor
has_related_synonym: phylloquinone reductase inhibitors
has_related_synonym: quinone reductase inhibitor
has_related_synonym: quinone reductase inhibitors
has_related_synonym: reduced NAD(P)H dehydrogenase inhibitor
has_related_synonym: reduced NAD(P)H dehydrogenase inhibitors
has_related_synonym: reduced nicotinamide-adenine dinucleotide (phosphate) dehydrogenase inhibitor
has_related_synonym: reduced nicotinamide-adenine dinucleotide (phosphate) dehydrogenase inhibitors
has_related_synonym: viologen accepting pyridine nucleotide oxidoreductase inhibitor
has_related_synonym: viologen accepting pyridine nucleotide oxidoreductase inhibitors
has_related_synonym: vitamin K reductase inhibitor
has_related_synonym: vitamin K reductase inhibitors
has_related_synonym: vitamin-K reductase inhibitor
has_related_synonym: vitamin-K reductase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

probe
type: Class
subclass of: application
definition: A role played by a molecular entity used to study the microscopic environment.
id: CHEBI:50406
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

acid-base indicator
type: Class
subclass of: colour indicator
definition: An acid or base which exhibits a colour change on neutralization by the basic or acidic titrant at or near the equivalence point of a titration.
id: CHEBI:50407
has_related_synonym: Saeure-Base-Indikator
has_related_synonym: Saeure-Base-Indikatoren
has_exact_synonym: acid-base indicator
has_obo_namespace: chebi_ontology
has_related_synonym: indicador acido-base
has_related_synonym: indicateur acide-base
in_subset: 3 STAR
imported from: chebi.owl

visual indicator
type: Class
subclass of: indicator
definition: Anything used in a scientific experiment that gives a visual change to indicate the presence of a substance or quality, change in a body, etc.
id: CHEBI:50408
has_obo_namespace: chebi_ontology
has_related_synonym: indicador visual
has_related_synonym: indicateur visuel
has_exact_synonym: visual indicator
in_subset: 3 STAR
imported from: chebi.owl

adsorption indicator
type: Class
subclass of: visual indicator
definition: A substance which is adsorbed or desorbed with concomitant colour change at or near the equivalence point of a titration.
id: CHEBI:50409
has_exact_synonym: adsorption indicator
has_obo_namespace: chebi_ontology
has_related_synonym: indicador de adsorcion
has_related_synonym: indicateur par adsorption
in_subset: 3 STAR
imported from: chebi.owl

colour indicator
type: Class
subclass of: visual indicator
id: CHEBI:50410
has_obo_namespace: chebi_ontology
has_exact_synonym: colour indicator
has_related_synonym: indicador de color
has_related_synonym: indicateur colore
has_related_synonym: indicateurs colores
in_subset: 3 STAR
imported from: chebi.owl

one-colour indicator
type: Class
subclass of: colour indicator
definition: A colour indicator that is colourless on one side of the transition interval.
id: CHEBI:50411
has_obo_namespace: chebi_ontology
has_related_synonym: indicador monocolor
has_related_synonym: indicador monocromico
has_related_synonym: indicateur monocolore
has_exact_synonym: one-colour indicator
in_subset: 3 STAR
imported from: chebi.owl

two-colour indicator
type: Class
subclass of: colour indicator
definition: A colour indicator that possesses a different colour on each side of the transition interval.
id: CHEBI:50412
has_obo_namespace: chebi_ontology
has_related_synonym: indicador bicolor
has_related_synonym: indicateur bicolore
has_exact_synonym: two-colour indicator
in_subset: 3 STAR
imported from: chebi.owl

EC 1.6.3.1. [NAD(P)H oxidase (H2O2-forming)] inhibitor
type: Class
subclass of: EC 1.6.3.* (oxidoreductase acting on NADH or NADPH with oxygen as acceptor) inhibitor
definition: An EC 1.6.3.* (oxidoreductase acting on NADH or NADPH with oxygen as acceptor) inhibitor that interferes with the action of NAD(P)H oxidase (H2O2-forming), EC 1.6.3.1.
id: CHEBI:50423
has_related_synonym: EC 1.6.3.1 inhibitor
has_related_synonym: EC 1.6.3.1 inhibitors
has_related_synonym: EC 1.6.3.1. (NAD(P)H oxidase (H2O2-forming)) inhibitor
has_related_synonym: EC 1.6.3.1. (NAD(P)H oxidase (H2O2-forming)) inhibitors
has_related_synonym: EC 1.6.3.1. [NAD(P)H oxidase (H2O2-forming)] inhibitors
has_related_synonym: NAD(P)H oxidase (H2O2-forming) (EC 1.6.3.1) inhibitor
has_related_synonym: NAD(P)H oxidase (H2O2-forming) (EC 1.6.3.1) inhibitors
has_related_synonym: NAD(P)H oxidase (H2O2-forming) inhibitor
has_related_synonym: NAD(P)H oxidase (H2O2-forming) inhibitors
has_related_synonym: NAD(P)H oxidase inhibitor
has_related_synonym: NAD(P)H oxidase inhibitors
has_related_synonym: NAD(P)H:oxygen oxidoreductase (H2O2-forming) inhibitor
has_related_synonym: NAD(P)H:oxygen oxidoreductase (H2O2-forming) inhibitors
has_related_synonym: NAD(P)H:oxygen oxidoreductase inhibitor
has_related_synonym: NAD(P)H:oxygen oxidoreductase inhibitors
has_related_synonym: NADPH oxidase inhibitor
has_related_synonym: NADPH oxidase inhibitors
has_related_synonym: THOX2 inhibitor
has_related_synonym: THOX2 inhibitors
has_related_synonym: ThOX inhibitor
has_related_synonym: ThOX inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: dual oxidase inhibitor
has_related_synonym: dual oxidase inhibitors
has_related_synonym: p138tox inhibitor
has_related_synonym: p138tox inhibitors
has_related_synonym: thyroid NADPH oxidase inhibitor
has_related_synonym: thyroid NADPH oxidase inhibitors
has_related_synonym: thyroid oxidase 2 inhibitor
has_related_synonym: thyroid oxidase 2 inhibitors
has_related_synonym: thyroid oxidase inhibitor
has_related_synonym: thyroid oxidase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

platelet aggregation inhibitor
type: Class
subclass of: hematologic agent
definition: A drug or agent which antagonizes or impairs any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
id: CHEBI:50427
has_obo_namespace: chebi_ontology
has_related_synonym: platelet aggregation inhibitors
in_subset: 3 STAR
imported from: chebi.owl

platelet glycoprotein-IIb/IIIa receptor antagonist
type: Class
subclass of: antagonist
subclass of: platelet aggregation inhibitor
definition: Antagonist of platelet surface glycoprotein-IIb/IIIa which has a key role in hemostasis and thrombosis such as platelet adhesion and aggregation.
id: CHEBI:50433
has_related_synonym: GPIIb/IIIa antagonist
has_related_synonym: GPIIb/IIIa antagonists
database_cross_reference: Wikipedia:Glycoprotein_IIb/IIIa_inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: fibrinogen receptor antagonist
has_related_synonym: fibrinogen receptor antagonists
has_related_synonym: glycoprotein-IIb/IIIa receptor antagonist
has_related_synonym: glycoprotein-IIb/IIIa receptor antagonists
has_related_synonym: platelet glycoprotein-IIb/IIIa receptor antagonists
in_subset: 3 STAR
imported from: chebi.owl

adenosine phosphodiesterase inhibitor
type: Class
subclass of: EC 3.1.4.* (phosphoric diester hydrolase) inhibitor
id: CHEBI:50444
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 3.5.4.4 (adenosine deaminase) inhibitor
type: Class
subclass of: EC 3.5.4.* (non-peptide cyclic amidine C-N hydrolase) inhibitor
has_related_synonym: ADA inhibitor
definition: An EC 3.5.4.* (non-peptide cyclic amidine C-N hydrolase) inhibitor that interferes with the action of adenosine deaminase (EC 3.5.4.4).
id: CHEBI:50445
has_related_synonym: EC 3.5.4.4 (adenosine deaminase) inhibitors
has_related_synonym: EC 3.5.4.4 inhibitor
has_related_synonym: EC 3.5.4.4 inhibitors
database_cross_reference: Wikipedia:Adenosine_deaminase
has_related_synonym: adenosine aminohydrolase inhibitor
has_related_synonym: adenosine aminohydrolase inhibitors
has_related_synonym: adenosine deaminase (EC 3.5.4.4) inhibitor
has_related_synonym: adenosine deaminase (EC 3.5.4.4) inhibitors
has_related_synonym: adenosine deaminase inhibitor
has_related_synonym: adenosine deaminase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: deoxyadenosine deaminase inhibitor
has_related_synonym: deoxyadenosine deaminase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.1.1.4 (phospholipase A2) inhibitor
type: Class
subclass of: EC 3.1.1.* (carboxylic ester hydrolase) inhibitor
definition: An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of phospholipase A2 (EC 3.1.1.4).
id: CHEBI:50469
has_related_synonym: EC 3.1.1.4 (phospholipase A2) inhibitors
has_related_synonym: EC 3.1.1.4 inhibitor
has_related_synonym: EC 3.1.1.4 inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: lecithinase A inhibitor
has_related_synonym: lecithinase A inhibitors
has_related_synonym: phosphatidase inhibitor
has_related_synonym: phosphatidase inhibitors
has_related_synonym: phosphatidolipase inhibitor
has_related_synonym: phosphatidolipase inhibitors
has_related_synonym: phosphatidylcholine 2-acylhydrolase inhibitor
has_related_synonym: phosphatidylcholine 2-acylhydrolase inhibitors
has_related_synonym: phospholipase A inhibitor
has_related_synonym: phospholipase A inhibitors
has_related_synonym: phospholipase A2 (EC 3.1.1.4) inhibitor
has_related_synonym: phospholipase A2 (EC 3.1.1.4) inhibitors
has_related_synonym: phospholipase A2 inhibitor
has_related_synonym: phospholipase A2 inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.5.1.15 (dihydropteroate synthase) inhibitor
type: Class
subclass of: EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor
has_related_synonym: (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl-diphosphate:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase inhibitor
has_related_synonym: (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl-diphosphate:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase inhibitors
has_related_synonym: 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine-diphosphate:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase inhibitor
has_related_synonym: 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine-diphosphate:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase inhibitors
has_related_synonym: 7,8-dihydropteroate synthase inhibitor
has_related_synonym: 7,8-dihydropteroate synthase inhibitors
has_related_synonym: 7,8-dihydropteroate synthetase inhibitor
has_related_synonym: 7,8-dihydropteroate synthetase inhibitors
has_related_synonym: 7,8-dihydropteroic acid synthetase inhibitor
has_related_synonym: 7,8-dihydropteroic acid synthetase inhibitors
definition: An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of dihydropteroate synthase (EC 2.5.1.15), an enzyme that catalyzes the formation of dihydropteroate from p-aminobenzoic acid and dihydropteridine-hydroxymethyl-pyrophosphate.
id: CHEBI:50502
has_related_synonym: DHPS inhibitor
has_related_synonym: DHPS inhibitors
has_related_synonym: EC 2.5.1.15 (dihydropteroate synthase) inhibitors
has_related_synonym: EC 2.5.1.15 inhibitor
has_related_synonym: EC 2.5.1.15 inhibitors
database_cross_reference: Wikipedia:Dihydropteroate_synthase_inhibitor
has_obo_namespace: chebi_ontology
has_related_synonym: dihydropteroate diphosphorylase inhibitor
has_related_synonym: dihydropteroate diphosphorylase inhibitors
has_related_synonym: dihydropteroate pyrophosphorylase inhibitor
has_related_synonym: dihydropteroate pyrophosphorylase inhibitors
has_related_synonym: dihydropteroate synthase (EC 2.5.1.15) inhibitor
has_related_synonym: dihydropteroate synthase (EC 2.5.1.15) inhibitors
has_related_synonym: dihydropteroate synthase inhibitor
has_related_synonym: dihydropteroate synthase inhibitors
has_related_synonym: dihydropteroate synthetase inhibitor
has_related_synonym: dihydropteroate synthetase inhibitors
has_related_synonym: dihydropteroic synthetase inhibitor
has_related_synonym: dihydropteroic synthetase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

laxative
type: Class
subclass of: drug
definition: An agent that produces a soft formed stool, and relaxes and loosens the bowels, typically used over a protracted period, to relieve constipation. Compare with cathartic, which is a substance that accelerates defecation. A substances can be both a laxative and a cathartic.
id: CHEBI:50503
has_related_synonym: aperient
has_related_synonym: aperients
has_obo_namespace: chebi_ontology
has_related_synonym: laxante
has_related_synonym: laxatives
has_related_synonym: purgative
has_related_synonym: purgatives
in_subset: 3 STAR
imported from: chebi.owl

osmotic diuretic
type: Class
subclass of: diuretic
id: CHEBI:50504
definition: Compound that increase urine volume by increasing the amount of osmotically active solute in the urine. It also increases the osmolarity of plasma.
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

sweetening agent
type: Class
subclass of: flavouring agent
id: CHEBI:50505
definition: Substance that sweeten food, beverages, medications, etc.
has_obo_namespace: chebi_ontology
has_related_synonym: sweetener
has_related_synonym: sweeteners
in_subset: 3 STAR
imported from: chebi.owl

appetite depressant
type: Class
subclass of: appetite regulator
definition: Any agent that is used to decrease appetite.
id: CHEBI:50507
has_related_synonym: appetite suppressant
has_related_synonym: appetite suppressants
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

potassium channel blocker
type: Class
subclass of: potassium channel modulator
definition: An agent that inhibits cell membrane glycoproteins that are selectively permeable to potassium ions.
id: CHEBI:50509
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

potassium channel modulator
type: Class
subclass of: membrane transport modulator
id: CHEBI:50510
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

mydriatic agent
type: Class
subclass of: drug
definition: Agent that dilates the pupil. Used in eye diseases and to facilitate eye examination. It may be either a sympathomimetic or parasympatholytic. The latter cause cycloplegia or paralysis of accommodation at high doses and may precipitate glaucoma.
id: CHEBI:50513
has_obo_namespace: chebi_ontology
has_related_synonym: mydriatics
in_subset: 3 STAR
imported from: chebi.owl

vasoconstrictor agent
type: Class
subclass of: cardiovascular drug
id: CHEBI:50514
definition: Drug used to cause constriction of the blood vessels.
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

protein denaturant
type: Class
subclass of: application
id: CHEBI:50533
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

nitric oxide donor
type: Class
subclass of: donor
definition: An agent, with unique chemical structure and biochemical requirements, which generates nitric oxide.
id: CHEBI:50566
has_alternative_id: CHEBI:77704
has_related_synonym: NO donor
has_related_synonym: NO donors
has_related_synonym: NO generator
has_related_synonym: NO generators
has_related_synonym: NO releasing agent
has_related_synonym: NO releasing agents
has_obo_namespace: chebi_ontology
has_related_synonym: nitric oxide donors
has_related_synonym: nitric oxide generators
has_related_synonym: nitric oxide releasing agent
has_related_synonym: nitric oxide releasing agents
in_subset: 3 STAR
imported from: chebi.owl

EC 3.1.4.17 (3',5'-cyclic-nucleotide phosphodiesterase) inhibitor
type: Class
subclass of: EC 3.1.4.* (phosphoric diester hydrolase) inhibitor
has_related_synonym: 3',5'-cyclic nucleoside monophosphate phosphodiesterase inhibitor
has_related_synonym: 3',5'-cyclic nucleoside monophosphate phosphodiesterase inhibitors
has_related_synonym: 3',5'-cyclic-nucleotide 5'-nucleotidohydrolase inhibitor
has_related_synonym: 3',5'-cyclic-nucleotide 5'-nucleotidohydrolase inhibitors
has_related_synonym: 3',5'-cyclic-nucleotide phosphodiesterase inhibitor
has_related_synonym: 3',5'-cyclic-nucleotide phosphodiesterase inhibitors
has_related_synonym: 3',5'-cyclonucleotide phosphodiesterase inhibitor
has_related_synonym: 3',5'-cyclonucleotide phosphodiesterase inhibitors
has_related_synonym: 3',5'-nucleotide phosphodiesterase inhibitor
has_related_synonym: 3',5'-nucleotide phosphodiesterase inhibitors
has_related_synonym: 3': 5'-monophosphate phosphodiesterase (cyclic CMP) inhibitor
has_related_synonym: 3': 5'-monophosphate phosphodiesterase (cyclic CMP) inhibitors
has_related_synonym: 3':5'-cyclic nucleotide 5'-nucleotidohydrolase inhibitor
has_related_synonym: 3':5'-cyclic nucleotide 5'-nucleotidohydrolase inhibitors
definition: An EC 3.1.4.* (phosphoric diester hydrolase) inhibitor which interferes with the action of 3',5'-cyclic-nucleotide phosphodiesterase (EC 3.1.4.17).
id: CHEBI:50568
has_related_synonym: EC 3.1.4.17 (3',5'-cyclic-nucleotide phosphodiesterase) inhibitors
has_related_synonym: EC 3.1.4.17 inhibitor
has_related_synonym: EC 3.1.4.17 inhibitors
has_related_synonym: PDE inhibitor
has_related_synonym: PDE inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: cyclic 3',5'-mononucleotide phosphodiesterase inhibitor
has_related_synonym: cyclic 3',5'-mononucleotide phosphodiesterase inhibitors
has_related_synonym: cyclic 3',5'-nucleotide phosphodiesterase inhibitor
has_related_synonym: cyclic 3',5'-nucleotide phosphodiesterase inhibitors
has_related_synonym: cyclic 3',5'-phosphodiesterase inhibitor
has_related_synonym: cyclic 3',5'-phosphodiesterase inhibitors
has_related_synonym: cyclic 3',5-nucleotide monophosphate phosphodiesterase inhibitor
has_related_synonym: cyclic 3',5-nucleotide monophosphate phosphodiesterase inhibitors
has_related_synonym: cyclic AMP phosphodiesterase inhibitor
has_related_synonym: cyclic AMP phosphodiesterase inhibitors
has_related_synonym: cyclic nucleotide phosphodiesterase inhibitor
has_related_synonym: cyclic nucleotide phosphodiesterase inhibitors
has_related_synonym: cytidine 3':5'-monophosphate phosphodiesterase (cyclic CMP) inhibitor
has_related_synonym: cytidine 3':5'-monophosphate phosphodiesterase (cyclic CMP) inhibitors
has_related_synonym: nucleoside 3',5'-cyclic phosphate diesterase inhibitor
has_related_synonym: nucleoside 3',5'-cyclic phosphate diesterase inhibitors
has_related_synonym: nucleoside-3',5-monophosphate phosphodiesterase inhibitor
has_related_synonym: nucleoside-3',5-monophosphate phosphodiesterase inhibitors
has_related_synonym: phosphodiesterase III inhibitor
in_subset: 3 STAR
imported from: chebi.owl

EC 3.2.1.1 (alpha-amylase) inhibitor
type: Class
subclass of: EC 3.2.1.* (glycosidase) inhibitor
has_related_synonym: 1,4-alpha-D-glucan glucanohydrolase inhibitor
has_related_synonym: 1,4-alpha-D-glucan glucanohydrolase inhibitors
has_related_synonym: 4-alpha-D-glucan glucanohydrolase inhibitor
has_related_synonym: 4-alpha-D-glucan glucanohydrolase inhibitors
definition: An EC 3.2.1.* (glycosidase) inhibitor that interferes with the action of alpha-amylase (EC 3.2.1.1).
id: CHEBI:50627
has_related_synonym: EC 3.2.1.1 (alpha-amylase) inhibitors
has_related_synonym: EC 3.2.1.1 inhibitor
has_related_synonym: EC 3.2.1.1 inhibitors
has_related_synonym: Taka-amylase A inhibitor
has_related_synonym: Taka-amylase A inhibitors
database_cross_reference: Wikipedia:Alpha-amylase
has_related_synonym: alpha-amylase (EC 3.2.1.1) inhibitor
has_related_synonym: alpha-amylase (EC 3.2.1.1) inhibitors
has_related_synonym: alpha-amylase inhibitor
has_related_synonym: alpha-amylase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: endoamylase inhibitor
has_related_synonym: endoamylase inhibitors
has_related_synonym: glycogenase inhibitor
has_related_synonym: glycogenase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

cyclooxygenase 2 inhibitor
type: Class
subclass of: EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor
definition: A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 2.
id: CHEBI:50629
has_related_synonym: COX-2 inhibitor
has_related_synonym: COX-2 inhibitors
has_related_synonym: PGHS-2 inhibitor
has_related_synonym: PGHS-2 inhibitors
database_cross_reference: Wikipedia:Prostaglandin-endoperoxide_synthase_2
has_obo_namespace: chebi_ontology
has_related_synonym: cyclo-oxygenase 2 inhibitor
has_related_synonym: cyclo-oxygenase 2 inhibitors
has_related_synonym: cyclo-oxygenase-2 inhibitor
has_related_synonym: cyclo-oxygenase-2 inhibitors
has_related_synonym: cyclooxygenase 2 inhibitors
has_related_synonym: cyclooxygenase-2 inhibitor
has_related_synonym: cyclooxygenase-2 inhibitors
has_related_synonym: prostaglandin H synthase-2 inhibitor
has_related_synonym: prostaglandin H synthase-2 inhibitors
has_related_synonym: prostaglandin-endoperoxide synthase 2 inhibitor
has_related_synonym: prostaglandin-endoperoxide synthase 2 inhibitors
in_subset: 3 STAR
imported from: chebi.owl

cyclooxygenase 1 inhibitor
type: Class
subclass of: EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor
definition: A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 1.
id: CHEBI:50630
has_related_synonym: COX-1 inhibitor
has_related_synonym: COX-1 inhibitors
has_related_synonym: PTGS1 inhibitor
has_related_synonym: PTGS1 inhibitors
database_cross_reference: Wikipedia:PTGS1
has_obo_namespace: chebi_ontology
has_related_synonym: cyclo-oxygenase 1 inhibitor
has_related_synonym: cyclo-oxygenase 1 inhibitors
has_related_synonym: cyclooxygenase 1 inhibitors
has_related_synonym: cyclooxygenase-1 inhibitor
has_related_synonym: cyclooxygenase-1 inhibitors
has_related_synonym: prostaglandin G/H synthase 1 inhibitor
has_related_synonym: prostaglandin G/H synthase 1 inhibitors
has_related_synonym: prostaglandin H2 synthase 1 inhibitor
has_related_synonym: prostaglandin H2 synthase 1 inhibitors
has_related_synonym: prostaglandin-endoperoxide synthase 1 inhibitor
has_related_synonym: prostaglandin-endoperoxide synthase 1 inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.5.1.5 (urease) inhibitor
type: Class
subclass of: EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor
id: CHEBI:50635
definition: EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the activity of urease (EC 3.5.1.5), reducing hydrolysis.
has_related_synonym: EC 3.5.1.5 (urease) inhibitors
has_related_synonym: EC 3.5.1.5 inhibitor
has_related_synonym: EC 3.5.1.5 inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: urea amidohydrolase inhibitor
has_related_synonym: urea amidohydrolase inhibitors
has_related_synonym: urease (EC 3.5.1.5) inhibitor
has_related_synonym: urease (EC 3.5.1.5) inhibitors
has_related_synonym: urease inhibitor
has_related_synonym: urease inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.5.1.1 (dimethylallyltranstransferase) inhibitor
type: Class
subclass of: EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor
has_related_synonym: (2E,6E)-farnesyl diphosphate synthetase inhibitor
has_related_synonym: (2E,6E)-farnesyl diphosphate synthetase inhibitors
definition: An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of dimethylallyltranstransferase (EC 2.5.1.1).
id: CHEBI:50643
has_related_synonym: DMAPP:IPP-dimethylallyltransferase inhibitor
has_related_synonym: DMAPP:IPP-dimethylallyltransferase inhibitors
has_related_synonym: EC 2.5.1.1 (dimethylallyltranstransferase) inhibitors
has_related_synonym: EC 2.5.1.1 inhibitor
has_related_synonym: EC 2.5.1.1 inhibitors
database_cross_reference: Wikipedia:Dimethylallyltranstransferase
has_obo_namespace: chebi_ontology
has_related_synonym: dimethylallyl-diphosphate:isopentenyl-diphosphate dimethylallyltranstransferase inhibitor
has_related_synonym: dimethylallyl-diphosphate:isopentenyl-diphosphate dimethylallyltranstransferase inhibitors
has_related_synonym: dimethylallyltransferase inhibitor
has_related_synonym: dimethylallyltransferase inhibitors
has_related_synonym: dimethylallyltranstransferase (EC 2.5.1.1) inhibitor
has_related_synonym: dimethylallyltranstransferase (EC 2.5.1.1) inhibitors
has_related_synonym: dimethylallyltranstransferase inhibitor
has_related_synonym: dimethylallyltranstransferase inhibitors
has_related_synonym: diprenyltransferase inhibitor
has_related_synonym: diprenyltransferase inhibitors
has_related_synonym: geranyl pyrophosphate synthase inhibitor
has_related_synonym: geranyl pyrophosphate synthase inhibitors
has_related_synonym: geranyl pyrophosphate synthetase inhibitor
has_related_synonym: geranyl pyrophosphate synthetase inhibitors
has_related_synonym: geranyl-diphosphate synthase inhibitor
has_related_synonym: geranyl-diphosphate synthase inhibitors
has_related_synonym: prenyltransferase inhibitor
has_related_synonym: prenyltransferase inhibitors
has_related_synonym: trans-farnesyl pyrophosphate synthetase inhibitor
has_related_synonym: trans-farnesyl pyrophosphate synthetase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

bone density conservation agent
type: Class
subclass of: drug
definition: An agent that inhibits bone resorption and/or favor bone mineralization and bone regeneration. Used to heal bone fractures and to treat bone diseases such as osteopenia and osteoporosis.
id: CHEBI:50646
has_alternative_id: CHEBI:72497
database_cross_reference: Wikipedia:Osteoporosis
has_related_synonym: anti-osteopenia agent
has_related_synonym: anti-osteopenia agents
has_related_synonym: anti-osteopenia drug
has_related_synonym: anti-osteopenia drugs
has_related_synonym: anti-osteoporosis agent
has_related_synonym: anti-osteoporosis agents
has_related_synonym: anti-osteoporosis drug
has_related_synonym: anti-osteoporosis drugs
has_related_synonym: anti-osteoporotic
has_related_synonym: anti-osteoporotic agent
has_related_synonym: anti-osteoporotic agents
has_related_synonym: anti-osteoporotic drug
has_related_synonym: anti-osteoporotic drugs
has_related_synonym: anti-osteoporotics
has_related_synonym: antiosteoporotic
has_related_synonym: antiosteoporotics
has_related_synonym: bone density conservation agents
has_related_synonym: bone density conservation drug
has_related_synonym: bone density conservation drugs
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

matrix metalloproteinase inhibitor
type: Class
subclass of: EC 3.4.* (hydrolases acting on peptide bond) inhibitor
id: CHEBI:50664
has_related_synonym: MMPI
has_obo_namespace: chebi_ontology
has_related_synonym: matrix metalloproteinase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

antithyroid drug
type: Class
subclass of: hormone antagonist
definition: A drug used to treat hyperthyroidism by reducing the excessive production of thyroid hormones.
id: CHEBI:50671
database_cross_reference: Wikipedia:Antithyroid_agent
has_related_synonym: antithyroid agent
has_related_synonym: antithyroid agents
has_related_synonym: antithyroid drugs
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 1.5.1.3 (dihydrofolate reductase) inhibitor
type: Class
subclass of: antifolate
subclass of: EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor) inhibitor
has_related_synonym: 7,8-dihydrofolate reductase inhibitor
has_related_synonym: 7,8-dihydrofolate reductase inhibitors
definition: An EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of dihydrofolate reductase (EC 1.5.1.3).
id: CHEBI:50683
has_related_synonym: DHFR inhibitor
has_related_synonym: DHFR inhibitors
has_related_synonym: EC 1.5.1.3 (dihydrofolate reductase) inhibitors
has_related_synonym: EC 1.5.1.3 inhibitor
has_related_synonym: EC 1.5.1.3 inhibitors
has_related_synonym: NADPH-dihydrofolate reductase inhibitor
has_related_synonym: NADPH-dihydrofolate reductase inhibitors
database_cross_reference: Wikipedia:Dihydrofolate_reductase_inhibitor
has_obo_namespace: chebi_ontology
has_related_synonym: dihydrofolate reductase (EC 1.5.1.3) inhibitor
has_related_synonym: dihydrofolate reductase (EC 1.5.1.3) inhibitors
has_related_synonym: dihydrofolate reductase inhibitor
has_related_synonym: dihydrofolate reductase inhibitors
has_related_synonym: dihydrofolic acid reductase inhibitor
has_related_synonym: dihydrofolic acid reductase inhibitors
has_related_synonym: dihydrofolic reductase inhibitor
has_related_synonym: dihydrofolic reductase inhibitors
has_related_synonym: folic acid reductase inhibitor
has_related_synonym: folic acid reductase inhibitors
has_related_synonym: folic reductase inhibitor
has_related_synonym: folic reductase inhibitors
has_related_synonym: tetrahydrofolate dehydrogenase inhibitor
has_related_synonym: tetrahydrofolate dehydrogenase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

cross-linking reagent
type: Class
subclass of: reagent
definition: A reagent with two reactive groups, usually at opposite ends of the molecule, that are capable of reacting with and thereby forming bridges between macromolecules, principally side chains of amino acids in proteins, allowing the locations of naturally reactive areas within the proteins to be identified.
id: CHEBI:50684
has_obo_namespace: chebi_ontology
has_related_synonym: cross-linking reagents
in_subset: 3 STAR
imported from: chebi.owl

antitrichomonal drug
type: Class
subclass of: antiprotozoal drug
definition: A drug used to treat trichomonas infections.
id: CHEBI:50685
has_related_synonym: antitrichomonal agent
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

reproductive control drug
type: Class
subclass of: drug
definition: A substance used either in the prevention or facilitation of pregnancy.
id: CHEBI:50689
has_obo_namespace: chebi_ontology
has_related_synonym: reproductive control agent
has_related_synonym: reproductive control drugs
in_subset: 3 STAR
imported from: chebi.owl

abortifacient
type: Class
subclass of: reproductive control drug
definition: A chemical substance that interrupts pregnancy after implantation.
id: CHEBI:50691
database_cross_reference: Wikipedia:Abortifacient
has_related_synonym: abortifacient agent
has_related_synonym: abortifacient agents
has_related_synonym: abortifacient drug
has_related_synonym: abortifacient drugs
has_related_synonym: abortifacients
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 2.4.1.129 (peptidoglycan glycosyltransferase) inhibitor
type: Class
subclass of: EC 2.4.1.* (hexosyltransferase) inhibitor
definition: An EC 2.4.1.* (hexosyltransferase) inhibitor that interferes with the action of peptidoglycan glycosyltransferase (EC 2.4.1.129).
id: CHEBI:50696
has_related_synonym: EC 2.4.1.129 (peptidoglycan glycosyltransferase) inhibitors
has_related_synonym: EC 2.4.1.129 inhibitor
has_related_synonym: EC 2.4.1.129 inhibitors
has_related_synonym: PBP3 inhibitor
has_related_synonym: PG-II inhibitor
has_related_synonym: PG-II inhibitors
has_related_synonym: [poly-N-acetyl-D-glucosaminyl-(1->4)-(N-acetyl-D-muramoylpentapeptide)]-diphosphoundecaprenol:[N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide]-diphosphoundecaprenol disaccharidetransferase inhibitor
has_related_synonym: [poly-N-acetyl-D-glucosaminyl-(1->4)-(N-acetyl-D-muramoylpentapeptide)]-diphosphoundecaprenol:[N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide]-diphosphoundecaprenol disaccharidetransferase inhibitors
has_related_synonym: bactoprenyldiphospho-N-acetylmuramoyl-(N-acetyl-D-glucosaminyl)-pentapeptide:peptidoglycan N-acetylmuramoyl-N-acetyl-D-glucosaminyltransferase inhibitor
has_related_synonym: bactoprenyldiphospho-N-acetylmuramoyl-(N-acetyl-D-glucosaminyl)-pentapeptide:peptidoglycan N-acetylmuramoyl-N-acetyl-D-glucosaminyltransferase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: penicillin binding protein 1B inhibitor
has_related_synonym: penicillin binding protein 1B inhibitors
has_related_synonym: penicillin binding protein 3 inhibitor
has_related_synonym: penicillin binding protein 3 inhibitors
has_related_synonym: peptidoglycan glycosyltransferase (EC 2.4.1.129) inhibitor
has_related_synonym: peptidoglycan glycosyltransferase (EC 2.4.1.129) inhibitors
has_related_synonym: peptidoglycan glycosyltransferase inhibitor
has_related_synonym: peptidoglycan glycosyltransferase inhibitors
has_related_synonym: peptidoglycan transglycosylase inhibitor
has_related_synonym: peptidoglycan transglycosylase inhibitors
has_related_synonym: undecaprenyldiphospho-(N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide):undecaprenyldiphospho-(N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide) disaccharidetransferase inhibitor
has_related_synonym: undecaprenyldiphospho-(N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide):undecaprenyldiphospho-(N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide) disaccharidetransferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

montelukast
type: Class
subclass of: molecular entity
has_related_synonym: (R-(E))-1-(((1-(3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropaneacetic acid
charge: 0
has_related_synonym: 1-[[[(1 R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl] phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]sulfanyl]methyl]cyclopropaneacetic acid
monoisotopicmass: 585.21044
mass: 586.18398
database_cross_reference: Beilstein:7896575
formula: C35H36ClNO3S
database_cross_reference: CAS:158966-92-8
has_alternative_id: CHEBI:49756
id: CHEBI:50730
has_alternative_id: CHEBI:6992
database_cross_reference: DrugBank:DB00471
database_cross_reference: Drug_Central:1836
inchi: InChI=1S/C35H36ClNO3S/c1-34(2,40)30-9-4-3-7-25(30)13-17-32(41-23-35(18-19-35)22-33(38)39)27-8-5-6-24(20-27)10-15-29-16-12-26-11-14-28(36)21-31(26)37-29/h3-12,14-16,20-21,32,40H,13,17-19,22-23H2,1-2H3,(H,38,39)/b15-10+/t32-/m1/s1
database_cross_reference: KEGG:C07482
database_cross_reference: KEGG:D08229
has_exact_synonym: MONTELUKAST
has_exact_synonym: Montelukast
database_cross_reference: PDBeChem:MTK
database_cross_reference: Patent:EP1886997
inchikey: UCHDWCPVSPXUMX-TZIWLTJVSA-N
database_cross_reference: Wikipedia:Montelukast
has_obo_namespace: chebi_ontology
has_related_synonym: montelukast
has_exact_synonym: {1-[({(1R)-1-{3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl}-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl}sulfanyl)methyl]cyclopropyl}acetic acid
in_subset: 3 STAR
imported from: chebi.owl

nutraceutical
type: Class
subclass of: drug
definition: A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance.
id: CHEBI:50733
has_related_synonym: Dietary Supplement
has_related_synonym: Food Supplementation
has_related_synonym: Nutritional supplement
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

estrogen receptor modulator
type: Class
subclass of: drug
definition: A substance that possess antiestrogenic actions but can also produce estrogenic effects as well. It acts as complete or partial agonist or as antagonist. It can be either steroidal or nonsteroidal in structure.
id: CHEBI:50739
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

retinoic acid receptor alpha/beta agonist
type: Class
subclass of: retinoic acid receptor agonist
definition: Any retinoic acid receptor (RAR) agonist with specificity for RARalpha and RARbeta.
id: CHEBI:50741
has_related_synonym: RAR alpha/beta agonist
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

progestogen
type: Class
subclass of: sex hormone
definition: A compound that interacts with progesterone receptors in target tissues to bring about effects similar to those of progesterone.
id: CHEBI:50745
has_obo_namespace: chebi_ontology
has_related_synonym: gestagen
has_related_synonym: gestagens
has_related_synonym: progestagen
has_related_synonym: progestagens
has_related_synonym: progestogens
in_subset: 3 STAR
imported from: chebi.owl

antipsoriatic
type: Class
subclass of: dermatologic drug
definition: A drug used to treat psoriasis.
id: CHEBI:50748
has_related_synonym: antipsoriatic agent
has_related_synonym: antipsoriatic drug
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
type: Class
subclass of: topoisomerase inhibitor
definition: A topoisomerase inhibitor that inhibits DNA topoisomerase (ATP-hydrolysing), EC 5.99.1.3 (also known as topoisomerase II and as DNA gyrase), which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands.
has_alternative_id: CHEBI:132229
has_alternative_id: CHEBI:50234
id: CHEBI:50750
has_related_synonym: DNA gyrase inhibitor
has_related_synonym: DNA gyrase inhibitors
has_related_synonym: DNA topoisomerase (ATP-hydrolysing) (EC 5.99.1.3) inhibitor
has_related_synonym: DNA topoisomerase (ATP-hydrolysing) (EC 5.99.1.3) inhibitors
has_related_synonym: DNA topoisomerase (ATP-hydrolysing) inhibitor
has_related_synonym: DNA topoisomerase (ATP-hydrolysing) inhibitors
has_related_synonym: DNA topoisomerase II inhibitor
has_related_synonym: DNA topoisomerase II inhibitors
has_related_synonym: EC 5.99.1.3 (DNA topoisomerase (ATP-hydrolysing)) inhibitor
has_related_synonym: EC 5.99.1.3 (DNA topoisomerase (ATP-hydrolysing)) inhibitors
has_related_synonym: EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitors
has_related_synonym: EC 5.99.1.3 inhibitor
has_related_synonym: EC 5.99.1.3 inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of type II topoisomerase
has_related_synonym: inhibitors of type II topoisomerase
has_related_synonym: topoisomerase II inhibitor
has_related_synonym: topoisomerase II inhibitors
has_related_synonym: topoisomerase-II inhibitor
has_related_synonym: topoisomerase-II inhibitors
has_related_synonym: type II DNA topoisomerase inhibitor
has_related_synonym: type II DNA topoisomerase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

anti-estrogen
type: Class
subclass of: drug
definition: A drug which acts to reduce estrogenic activity in the body, either by reducing the amount of estrogen or by reducing the activity of whatever estrogen is present.
id: CHEBI:50751
database_cross_reference: Wikipedia:Antiestrogen
has_related_synonym: anti-estrogenic agent
has_related_synonym: anti-estrogenic drug
has_related_synonym: anti-oestrogen
has_related_synonym: anti-oestrogenic agent
has_related_synonym: anti-oestrogenic drug
has_related_synonym: antiestrogen
has_related_synonym: antiestrogenic agent
has_related_synonym: antiestrogenic drug
has_related_synonym: antioestrogen
has_related_synonym: antioestrogenic agent
has_related_synonym: antioestrogenic drug
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

appetite enhancer
type: Class
subclass of: appetite regulator
definition: A drug which increases appetite.
id: CHEBI:50779
database_cross_reference: Wikipedia:Appetite_stimulants
has_related_synonym: appetite enhancing drug
has_related_synonym: appetite stimulant
has_obo_namespace: chebi_ontology
has_related_synonym: orexigenic
in_subset: 3 STAR
imported from: chebi.owl

appetite regulator
type: Class
subclass of: drug
definition: An agent which regulates the physiologic mechanisms that control the appetite and food intake.
id: CHEBI:50780
has_related_synonym: appetite regulators
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor
type: Class
subclass of: EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor
has_related_synonym: 3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+)) (EC 1.3.1.22) inhibitor
has_related_synonym: 3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+)) (EC 1.3.1.22) inhibitors
has_related_synonym: 3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+)) inhibitor
has_related_synonym: 3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+)) inhibitors
has_related_synonym: 3-oxo-5alpha-steroid 4-dehydrogenase inhibitor
has_related_synonym: 3-oxo-5alpha-steroid 4-dehydrogenase inhibitors
has_related_synonym: 3-oxo-5alpha-steroid:NADP+ Delta(4)-oxidoreductase inhibitor
has_related_synonym: 3-oxo-5alpha-steroid:NADP+ Delta(4)-oxidoreductase inhibitors
has_related_synonym: 3-oxosteroid 5alpha-reductase inhibitor
has_related_synonym: 3-oxosteroid Delta4-dehydrogenase inhibitor
has_related_synonym: 4-ene-3-oxosteroid 5alpha-reductase inhibitor
has_related_synonym: 4-ene-5alpha-reductase inhibitor
has_related_synonym: 5alpha-oxidoreductase inhibitor
has_related_synonym: 5alpha-oxidoreductase inhibitors
has_related_synonym: 5alpha-reductase inhibitor
has_related_synonym: 5alpha-reductase inhibitors
definition: An EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor, NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of of 3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+)), EC 1.3.1.22, the enzyme which converts testosterone (CHEBI:17347) into the more potent androgen 5alpha-dihydrotestosterone.
id: CHEBI:50781
has_related_synonym: Delta(4)-3-ketosteroid 5alpha-oxidoreductase inhibitor
has_related_synonym: Delta(4)-3-ketosteroid 5alpha-oxidoreductase inhibitors
has_related_synonym: EC 1.3.1.22 (3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))) inhibitor
has_related_synonym: EC 1.3.1.22 (3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))) inhibitors
has_related_synonym: EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitors
has_related_synonym: EC 1.3.1.22 inhibitor
has_related_synonym: EC 1.3.1.22 inhibitors
database_cross_reference: Wikipedia:5-alpha-reductase_inhibitor
has_obo_namespace: chebi_ontology
has_related_synonym: cholest-4-en-3-one 5alpha-reductase inhibitor
has_related_synonym: cholestenone 5alpha-reductase inhibitor
has_related_synonym: cholestenone 5alpha-reductase inhibitors
has_related_synonym: reduced nicotinamide adenine dinucleotide phosphate:Delta(4)-3-ketosteroid 5alpha-oxidoreductase inhibitor
has_related_synonym: reduced nicotinamide adenine dinucleotide phosphate:Delta(4)-3-ketosteroid 5alpha-oxidoreductase inhibitors
has_related_synonym: steroid 5alpha-hydrogenase inhibitor
has_related_synonym: steroid 5alpha-hydrogenase inhibitors
has_related_synonym: steroid 5alpha-reductase inhibitor
has_related_synonym: steroid 5alpha-reductase inhibitors
has_related_synonym: testosterone 5alpha-reductase inhibitor
has_related_synonym: testosterone 5alpha-reductase inhibitors
has_related_synonym: testosterone Delta(4)-5alpha-reductase inhibitor
has_related_synonym: testosterone Delta(4)-5alpha-reductase inhibitors
has_related_synonym: testosterone Delta(4)-hydrogenase inhibitor
has_related_synonym: testosterone Delta(4)-hydrogenase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.1.1.210 [3beta(or 20alpha)-hydroxysteroid dehydrogenase] inhibitor
type: Class
subclass of: EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor
has_related_synonym: 3beta (or 20alpha)-hydroxysteroid dehydrogenase inhibitor
has_related_synonym: 3beta (or 20alpha)-hydroxysteroid dehydrogenase inhibitors
has_related_synonym: 3beta(or 20alpha)-hydroxysteroid dehydrogenase (EC 1.1.1.210) inhibitor
has_related_synonym: 3beta(or 20alpha)-hydroxysteroid dehydrogenase (EC 1.1.1.210) inhibitors
has_related_synonym: 3beta(or 20alpha)-hydroxysteroid dehydrogenase inhibitor
has_related_synonym: 3beta(or 20alpha)-hydroxysteroid dehydrogenase inhibitors
has_related_synonym: 3beta(or 20alpha)-hydroxysteroid:NADP(+) oxidoreductase inhibitor
has_related_synonym: 3beta(or 20alpha)-hydroxysteroid:NADP(+) oxidoreductase inhibitors
has_related_synonym: 3beta,20alpha-hydroxysteroid oxidoreductase inhibitor
has_related_synonym: 3beta,20alpha-hydroxysteroid oxidoreductase inhibitors
has_related_synonym: 3beta-HSD
has_related_synonym: 3beta-hydroxysteroid dehydrogenase
has_related_synonym: 3beta-hydroxysteroid dehydrogenase inhibitor
definition: An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor which interferes with the action of 3beta-hydroxysteroid dehydrogenase (EC 1.1.1.210), a group of steroidogenic enzymes.
id: CHEBI:50788
has_related_synonym: EC 1.1.1.210 (3beta(or 20alpha)-hydroxysteroid dehydrogenase) inhibitor
has_related_synonym: EC 1.1.1.210 (3beta(or 20alpha)-hydroxysteroid dehydrogenase) inhibitors
has_related_synonym: EC 1.1.1.210 [3beta(or 20alpha)-hydroxysteroid dehydrogenase] inhibitors
has_related_synonym: EC 1.1.1.210 inhibitor
has_related_synonym: EC 1.1.1.210 inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: dehydrogenase, 3beta,20alpha-hydroxy steroid inhibitor
has_related_synonym: dehydrogenase, 3beta,20alpha-hydroxy steroid inhibitors
has_related_synonym: progesterone reductase inhibitor
has_related_synonym: progesterone reductase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.14.14.14 (aromatase) inhibitor
type: Class
subclass of: EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor
definition: An EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor which interferes with the action of aromatase (EC 1.14.14.14) and so reduces production of estrogenic steroid hormones.
id: CHEBI:50790
has_related_synonym: EC 1.14.14.14 (aromatase) inhibitors
has_related_synonym: EC 1.14.14.14 inhibitor
has_related_synonym: EC 1.14.14.14 inhibitors
database_cross_reference: Wikipedia:Aromatase_inhibitor
has_related_synonym: aromatase (EC 1.14.14.14) inhibitor
has_related_synonym: aromatase (EC 1.14.14.14) inhibitors
has_related_synonym: aromatase inhibitor
has_related_synonym: aromatase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: estrogen synthase inhibitor
has_related_synonym: estrogen synthase inhibitors
has_related_synonym: estrogen synthetase inhibitor
has_related_synonym: estrogen synthetase inhibitors
has_related_synonym: oestrogen synthase inhibitor
has_related_synonym: oestrogen synthase inhibitors
has_related_synonym: oestrogen synthetase inhibitor
has_related_synonym: oestrogen synthetase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

estrogen receptor antagonist
type: Class
subclass of: drug
subclass of: antagonist
definition: An antagonist at the estrogen receptor.
id: CHEBI:50792
has_obo_namespace: chebi_ontology
has_related_synonym: estrogen receptor antagonists
in_subset: 3 STAR
imported from: chebi.owl

antiparathyroid drug
type: Class
subclass of: hormone antagonist
definition: A drug used to treat hyperparathyroidism by reducing the excessive production of parathyroid hormones.
id: CHEBI:50827
has_related_synonym: antiparathyroid agent
has_related_synonym: antiparathyroid agents
has_related_synonym: antiparathyroid drugs
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

estrogen antagonist
type: Class
subclass of: hormone antagonist
definition: A compound which inhibits or antagonises the biosynthesis or actions of estrogens.
id: CHEBI:50837
has_obo_namespace: chebi_ontology
has_related_synonym: oestrogen antagonist
in_subset: 3 STAR
imported from: chebi.owl

antimineralocorticoid
type: Class
subclass of: hormone antagonist
definition: A compound which inhibits or antagonizes the biosynthesis or actions of mineralocorticoids, a class of steroid hormones characterised by their similarity to aldosterone and their influence on salt and water balance.
id: CHEBI:50843
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

aldosterone antagonist
type: Class
subclass of: antimineralocorticoid
id: CHEBI:50844
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

immunomodulator
type: Class
subclass of: drug
subclass of: biological role
definition: Biologically active substance whose activity affects or plays a role in the functioning of the immune system.
has_related_synonym: Biomodulator
id: CHEBI:50846
has_related_synonym: Immune factor
has_related_synonym: Immunologic factor
has_related_synonym: Immunological factor
database_cross_reference: Wikipedia:Immunotherapy
has_obo_namespace: chebi_ontology
has_related_synonym: immunomodulators
in_subset: 3 STAR
imported from: chebi.owl

immunological adjuvant
type: Class
subclass of: immunomodulator
subclass of: adjuvant
definition: A substance that augments, stimulates, activates, potentiates, or modulates the immune response at either the cellular or humoral level. A classical agent (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contains bacterial antigens. It could also be endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Its mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy is related to its antigen-specific immunoadjuvanticity.
id: CHEBI:50847
has_related_synonym: Immunoactivator
has_related_synonym: Immunoadjuvant
has_related_synonym: Immunologic adjuvant
has_related_synonym: Immunopotentiator
has_related_synonym: Immunostimulant
database_cross_reference: Wikipedia:Immunologic_adjuvant
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

antiatherogenic agent
type: Class
subclass of: cardiovascular drug
definition: A cardiovascular drug that prevents atherogenesis, the accumulation of lipid-containing plaques on the innermost layers of the arteries. Compare with antiatherosclerotic agent.
id: CHEBI:50855
database_cross_reference: PMID:14592471
database_cross_reference: PMID:16366593
database_cross_reference: PMID:17990280
database_cross_reference: PMID:20222342
database_cross_reference: PMID:21074432
database_cross_reference: PMID:21172387
database_cross_reference: PMID:21649483
database_cross_reference: PMID:3288054
database_cross_reference: PMID:9796331
has_related_synonym: anti-atherogenic agent
has_related_synonym: anti-atherogenic agents
has_related_synonym: anti-atherogenic drug
has_related_synonym: anti-atherogenic drugs
has_exact_synonym: antiatherogenic agent
has_related_synonym: antiatherogenic agents
has_related_synonym: antiatherogenic drug
has_related_synonym: antiatherogenic drugs
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

anti-allergic agent
type: Class
subclass of: drug
definition: A drug used to treat allergic reactions.
id: CHEBI:50857
has_related_synonym: anti-allergic agents
has_related_synonym: anti-allergic drug
has_related_synonym: anti-allergic drugs
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

insulin-sensitizing drug
type: Class
subclass of: hypoglycemic agent
subclass of: agonist
subclass of: PPAR modulator
definition: An agent which overcomes insulin resistance by activation of the peroxisome proliferator activated receptor gamma (PPAR-gamma).
id: CHEBI:50864
has_related_synonym: PPAR-gamma agonist
has_related_synonym: PPAR-gamma agonists
has_related_synonym: PPARgamma agonist
has_related_synonym: PPARgamma agonists
has_obo_namespace: chebi_ontology
has_related_synonym: glitazonas
has_related_synonym: glitazone drug
has_related_synonym: glitazones
has_related_synonym: insulin sensitisers
has_related_synonym: insulin sensitizers
has_related_synonym: insulin-sensitising drug
has_related_synonym: insulin-sensitizing agent
has_related_synonym: peroxisome proliferator-activated receptor gamma agonist
has_related_synonym: peroxisome proliferator-activated receptor gamma agonists
has_related_synonym: proliferator activated receptor gamma agonist
has_related_synonym: proliferator activated receptor gamma agonists
has_related_synonym: thiazolidinediones
has_related_synonym: tiazolidinedionas
in_subset: 3 STAR
imported from: chebi.owl

genotoxin
type: Class
subclass of: aetiopathogenetic role
definition: A role played by a chemical compound to induce direct or indirect DNA damage. Such damage can potentially lead to the formation of a malignant tumour, but DNA damage does not lead inevitably to the creation of cancerous cells.
id: CHEBI:50902
database_cross_reference: Wikipedia:Genotoxicity
has_obo_namespace: chebi_ontology
has_related_synonym: genotoxic agent
has_related_synonym: genotoxic agents
has_related_synonym: genotoxins
in_subset: 3 STAR
imported from: chebi.owl

carcinogenic agent
type: Class
subclass of: aetiopathogenetic role
definition: A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities.
id: CHEBI:50903
has_related_synonym: agente carcinogeno
has_related_synonym: cancerigene
has_related_synonym: cancerogene
has_related_synonym: carcinogen
has_related_synonym: carcinogene
has_related_synonym: carcinogenic agents
has_related_synonym: carcinogeno
has_related_synonym: carcinogens
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

allergen
type: Class
subclass of: aetiopathogenetic role
definition: A chemical compound, or part thereof, which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy.
id: CHEBI:50904
database_cross_reference: Wikipedia:Allergen
has_related_synonym: alergeno
has_related_synonym: allergene
has_related_synonym: allergenic agent
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

teratogenic agent
type: Class
subclass of: aetiopathogenetic role
definition: A role played by a chemical compound in biological systems with adverse consequences in embryo developments, leading to birth defects, embryo death or altered development, growth retardation and functional defect.
id: CHEBI:50905
has_related_synonym: agent teratogene
has_obo_namespace: chebi_ontology
has_related_synonym: teratogen
has_related_synonym: teratogeno
in_subset: 3 STAR
imported from: chebi.owl

deaminating agent
type: Class
subclass of: chemical role
definition: A deaminating agent is a role played by a chemical agent which exhibits the capability of causing the loss of an amine functional group on another molecular entity (e.g. DNA or protein).
id: CHEBI:50907
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

hepatotoxic agent
type: Class
subclass of: aetiopathogenetic role
definition: A role played by a chemical compound exhibiting itself through the ability to induce damage to the liver in animals.
id: CHEBI:50908
has_related_synonym: agente hepatotoxico
has_obo_namespace: chebi_ontology
has_related_synonym: hepatotoxic agents
has_related_synonym: hepatotoxicant
has_related_synonym: hepatotoxicants
has_related_synonym: hepatotoxin
has_related_synonym: hepatotoxins
has_related_synonym: hepatoxic agent
has_related_synonym: hepatoxicant
in_subset: 3 STAR
imported from: chebi.owl

nephrotoxic agent
type: Class
subclass of: aetiopathogenetic role
definition: A role played by any chemical compound (natural or synthetic) exhibiting itself through the ability to induce damage to the kidneys.
id: CHEBI:50909
has_related_synonym: agente nefrotoxico
has_obo_namespace: chebi_ontology
has_related_synonym: nephrotoxic agents
has_related_synonym: nephrotoxicant
in_subset: 3 STAR
imported from: chebi.owl

neurotoxin
type: Class
subclass of: aetiopathogenetic role
subclass of: poison
definition: A poison that interferes with the functions of the nervous system.
id: CHEBI:50910
has_alternative_id: CHEBI:50911
database_cross_reference: Wikipedia:Neurotoxin
has_related_synonym: agente neurotoxico
has_obo_namespace: chebi_ontology
has_related_synonym: nerve poison
has_related_synonym: nerve poisons
has_related_synonym: neurotoxic agent
has_related_synonym: neurotoxic agents
has_related_synonym: neurotoxicant
has_related_synonym: neurotoxins
in_subset: 3 STAR
imported from: chebi.owl

cardiotoxic agent
type: Class
subclass of: aetiopathogenetic role
definition: A role played by a chemical compound exhibiting itself through the ability to induce damage to the heart and cardiomyocytes.
id: CHEBI:50912
has_related_synonym: cardiotoxicant
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

fixative
type: Class
subclass of: biological role
definition: Any compound used for the purpose of preserving biological tissues from decay in such a way as to allow for the preparation of thin, stained sections for subsequent histological study.
id: CHEBI:50913
database_cross_reference: Wikipedia:Fixation_(histology)
has_obo_namespace: chebi_ontology
has_related_synonym: fixating agent
has_related_synonym: fixating agents
has_related_synonym: fixation agent
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
type: Class
subclass of: lipid kinase inhibitor
subclass of: EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor
has_related_synonym: 1-phosphatidylinositol 3-kinase inhibitor
has_related_synonym: 1-phosphatidylinositol 3-kinase inhibitors
has_related_synonym: ATP:1-phosphatidyl-1D-myo-inositol 3-phosphotransferase inhibitor
has_related_synonym: ATP:1-phosphatidyl-1D-myo-inositol 3-phosphotransferase inhibitors
definition: An inhibitor of phosphatidylinositol 3-kinase, EC 2.7.1.137, a family of related enzymes capable of phosphorylating the 3 position hydroxy group of the inositol ring of a phosphatidylinositol.
id: CHEBI:50914
has_related_synonym: EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitors
has_related_synonym: EC 2.7.1.137 inhibitor
has_related_synonym: EC 2.7.1.137 inhibitors
has_related_synonym: PI(3)K inhibitor
has_related_synonym: PI(3)K inhibitors
has_related_synonym: PI-3 kinase inhibitor
has_related_synonym: PI-3 kinase inhibitors
has_related_synonym: PI3-kinase inhibitor
has_related_synonym: PI3-kinase inhibitors
has_related_synonym: PI3K inhibitor
has_related_synonym: PI3K inhibitors
has_related_synonym: PtdIns-3-kinase inhibitor
has_related_synonym: PtdIns-3-kinase inhibitors
has_related_synonym: Vps34p inhibitor
has_related_synonym: Vps34p inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: phosphatidylinositol 3-kinase (EC 2.7.1.137) inhibitor
has_related_synonym: phosphatidylinositol 3-kinase (EC 2.7.1.137) inhibitors
has_related_synonym: phosphatidylinositol 3-kinase inhibitor
has_related_synonym: phosphatidylinositol 3-kinase inhibitors
has_related_synonym: phosphatidylinositol-3-OH kinase inhibitor
has_related_synonym: phosphatidylinositol-3-OH kinase inhibitors
has_related_synonym: phosphoinositide 3-kinase inhibitor
has_related_synonym: phosphoinositide 3-kinase inhibitors
has_related_synonym: type I phosphatidylinositol kinase inhibitor
has_related_synonym: type I phosphatidylinositol kinase inhibitors
has_related_synonym: type III phosphoinositide 3-kinase inhibitor
has_related_synonym: type III phosphoinositide 3-kinase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

lipid kinase inhibitor
type: Class
subclass of: EC 2.7.* (P-containing group transferase) inhibitor
definition: An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of lipid kinases.
id: CHEBI:50916
has_obo_namespace: chebi_ontology
has_related_synonym: lipid kinase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

antiemetic
type: Class
subclass of: drug
definition: A drug used to prevent nausea or vomiting. An antiemetic may act by a wide range of mechanisms: it might affect the medullary control centres (the vomiting centre and the chemoreceptive trigger zone) or affect the peripheral receptors.
id: CHEBI:50919
database_cross_reference: Wikipedia:Antiemetic
has_related_synonym: anti-emetic
has_related_synonym: anti-emetics
has_related_synonym: antiemetico
has_related_synonym: antiemetics
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor
type: Class
subclass of: EC 2.7.11.* (protein-serine/threonine kinase) inhibitor
has_related_synonym: A-kinase inhibitor
has_related_synonym: A-kinase inhibitors
has_related_synonym: AP50 kinase inhibitor
has_related_synonym: AP50 kinase inhibitors
has_related_synonym: ATP-protein transphosphorylase inhibitor
has_related_synonym: ATP-protein transphosphorylase inhibitors
has_related_synonym: ATP:protein phosphotransferase (non-specific) inhibitor
has_related_synonym: ATP:protein phosphotransferase (non-specific) inhibitors
definition: An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of non-specific serine/threonine protein kinase (EC 2.7.11.1), a kinase enzyme involved in phosphorylation of hydroxy group of serine or threonine.
has_related_synonym: BR serine/threonine-protein kinase 2 inhibitor
has_related_synonym: BR serine/threonine-protein kinase 2 inhibitors
id: CHEBI:50925
has_alternative_id: CHEBI:75764
has_related_synonym: CK-2 inhibitor
has_related_synonym: CK-2 inhibitors
has_related_synonym: CKI inhibitor
has_related_synonym: CKI inhibitors
has_related_synonym: CKII inhibitor
has_related_synonym: CKII inhibitors
has_related_synonym: EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitors
has_related_synonym: EC 2.7.11.1 inhibitor
has_related_synonym: EC 2.7.11.1 inhibitors
has_related_synonym: HIPK2 inhibitor
has_related_synonym: HIPK2 inhibitors
has_related_synonym: Hpr kinase inhibitor
has_related_synonym: Hpr kinase inhibitors
has_related_synonym: M phase-specific cdc2 kinase inhibitor
has_related_synonym: M phase-specific cdc2 kinase inhibitors
has_related_synonym: MKNK2 inhibitor
has_related_synonym: MKNK2 inhibitors
has_related_synonym: PAK-1 inhibitor
has_related_synonym: PAK-1 inhibitors
has_related_synonym: PAK1 inhibitor
has_related_synonym: PAK1 inhibitors
has_related_synonym: PKA inhibitor
has_related_synonym: PKA inhibitors
has_related_synonym: Prp4 protein kinase inhibitor
has_related_synonym: Prp4 protein kinase inhibitors
has_related_synonym: Raf kinase inhibitor
has_related_synonym: Raf kinase inhibitors
has_related_synonym: Raf-1 inhibitor
has_related_synonym: Raf-1 inhibitors
has_related_synonym: STK32 inhibitor
has_related_synonym: STK32 inhibitors
has_related_synonym: T-antigen kinase inhibitor
has_related_synonym: T-antigen kinase inhibitors
has_related_synonym: WEE1Hu inhibitor
has_related_synonym: WEE1Hu inhibitors
has_related_synonym: Wee 1-like kinase inhibitor
has_related_synonym: Wee 1-like kinase inhibitors
has_related_synonym: Wee-kinase inhibitor
has_related_synonym: Wee-kinase inhibitors
has_related_synonym: betaIIPKC inhibitor
has_related_synonym: betaIIPKC inhibitors
has_related_synonym: cAMP-dependent protein kinase A inhibitor
has_related_synonym: cAMP-dependent protein kinase A inhibitors
has_related_synonym: cAMP-dependent protein kinase inhibitor
has_related_synonym: cAMP-dependent protein kinase inhibitors
has_related_synonym: cGMP-dependent protein kinase inhibitor
has_related_synonym: cGMP-dependent protein kinase inhibitors
has_related_synonym: calcium-dependent protein kinase C inhibitor
has_related_synonym: calcium-dependent protein kinase C inhibitors
has_related_synonym: calcium/phospholipid-dependent protein kinase inhibitor
has_related_synonym: calcium/phospholipid-dependent protein kinase inhibitors
has_related_synonym: casein kinase (phosphorylating) inhibitor
has_related_synonym: casein kinase (phosphorylating) inhibitors
has_related_synonym: casein kinase 2 inhibitor
has_related_synonym: casein kinase 2 inhibitors
has_related_synonym: casein kinase I inhibitor
has_related_synonym: casein kinase I inhibitors
has_related_synonym: casein kinase II inhibitor
has_related_synonym: casein kinase II inhibitors
has_related_synonym: casein kinase inhibitor
has_related_synonym: casein kinase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: cyclic AMP-dependent protein kinase A inhibitor
has_related_synonym: cyclic AMP-dependent protein kinase A inhibitors

angiogenesis modulating agent
type: Class
subclass of: drug
definition: An agent that modulates the physiologic angiogenesis process. This is accomplished by endogenous angiogenic proteins and a variety of other chemicals and pharmaceutical agents.
id: CHEBI:50926
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

serotonin uptake inhibitor
type: Class
subclass of: serotonergic drug
definition: A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent.
id: CHEBI:50949
has_related_synonym: SSRI
database_cross_reference: Wikipedia:Selective_serotonin_reuptake_inhibitor
has_obo_namespace: chebi_ontology
has_related_synonym: serotonin reuptake inhibitor
in_subset: 3 STAR
imported from: chebi.owl

dopamine uptake inhibitor
type: Class
subclass of: dopaminergic agent
definition: A dopaminergic agent that blocks the transport of dopamine into axon terminals or into storage vesicles within terminals. Most of the adrenergic uptake inhibitors also inhibit dopamine uptake.
id: CHEBI:51039
has_related_synonym: DARI
has_related_synonym: DRI
database_cross_reference: Wikipedia:Dopamine_uptake_inhibitor
has_obo_namespace: chebi_ontology
has_related_synonym: dopamine reuptake inhibitor
has_related_synonym: dopamine reuptake inhibitors
has_related_synonym: dopamine uptake inhibitors
in_subset: 3 STAR
imported from: chebi.owl

hormone agonist
type: Class
subclass of: agonist
subclass of: hormone receptor modulator
definition: A chemical substance which binds to specific hormone receptors activating the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites.
id: CHEBI:51060
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

hormone receptor modulator
type: Class
subclass of: drug
subclass of: receptor modulator
definition: A drug that modulates the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites.
id: CHEBI:51061
has_obo_namespace: chebi_ontology
has_related_synonym: hormone receptor modulators
in_subset: 3 STAR
imported from: chebi.owl

dopamine agonist
type: Class
subclass of: dopaminergic agent
definition: A drug that binds to and activates dopamine receptors.
has_related_synonym: Agonista dopaminergico
id: CHEBI:51065
has_related_synonym: Dopamine receptor agonist
has_related_synonym: Dopaminergic agonist
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

miotic
type: Class
subclass of: neurotransmitter agent
definition: An agent causing contraction of the pupil of the eye. Because the size of the pupil is under the antagonistic control of the sympathetic and parasympathetic systems, drugs affecting either system can cause miosis. Drugs that mimic or potentiate the parasympathetic input to the circular constrictor muscle and drugs that inhibit sympathetic input to the radial dilator muscle tend to contract the pupils.
id: CHEBI:51068
has_related_synonym: Miotico
has_obo_namespace: chebi_ontology
has_related_synonym: miotics
in_subset: 3 STAR
imported from: chebi.owl

antifouling biocide
type: Class
subclass of: pesticide
definition: A compound that inhibits the growth of marine organisms.
has_related_synonym: Antifoulant
has_related_synonym: Antifouling agent
id: CHEBI:51076
has_related_synonym: Marine pesticide
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

chemical role
type: Class
subclass of: BAO_0002929
definition: A role played by the molecular entity or part thereof within a chemical context.
id: CHEBI:51086
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

protecting group
type: Class
subclass of: application
definition: A group that is introduced into a molecule by chemical modification of a functional group in order to obtain chemoselectivity in a subsequent chemical reaction.
id: CHEBI:51087
has_related_synonym: Schutzgruppe
has_related_synonym: Schutzgruppen
has_obo_namespace: chebi_ontology
has_related_synonym: groupe protecteur
has_related_synonym: protective group
in_subset: 3 STAR
imported from: chebi.owl

fluorescent dye
type: Class
subclass of: dye
id: CHEBI:51121
has_obo_namespace: chebi_ontology
has_related_synonym: fluorescent dyes
in_subset: 3 STAR
imported from: chebi.owl

Wittig reagent
type: Class
subclass of: reagent
definition: A role played by a phosphonium ylide in a Wittig reaction.
id: CHEBI:51166
has_exact_synonym: Wittig reagents
has_obo_namespace: chebi_ontology
has_related_synonym: reactif de Wittig
has_related_synonym: reactivo de Wittig
has_related_synonym: reactivos de Wittig
in_subset: 3 STAR
imported from: chebi.owl

antitussive
type: Class
subclass of: drug
definition: An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
id: CHEBI:51177
has_related_synonym: anti-tussive
has_obo_namespace: chebi_ontology
has_related_synonym: cough suppressant
has_related_synonym: cough suppressants
in_subset: 3 STAR
imported from: chebi.owl

fluorochrome
type: Class
subclass of: fluorescent dye
definition: A fluorescent dye used to stain biological specimens.
id: CHEBI:51217
has_obo_namespace: chebi_ontology
has_related_synonym: fluorochromes
in_subset: 3 STAR
imported from: chebi.owl

Grignard reagent
type: Class
subclass of: reagent
definition: A role played by an organomagnesium halide in a Grignard reaction.
id: CHEBI:51237
has_related_synonym: Grignards Reagens
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

gelator
type: Class
subclass of: reagent
id: CHEBI:51266
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

swelling agent
type: Class
subclass of: reagent
definition: A role played by a compound in a fluid state in swelling a gel, network, or solid.
id: CHEBI:51267
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

drying control chemical additive
type: Class
subclass of: solvent
definition: A role played by a compound that facilitates the rapid drying of gels without their cracking.
id: CHEBI:51268
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

muscle relaxant
type: Class
subclass of: neuromuscular agent
definition: A drug used to produce muscle relaxation (excepting neuromuscular blocking agents). Its primary clinical and therapeutic use is the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. Also used for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in multiple sclerosis.
id: CHEBI:51371
has_obo_namespace: chebi_ontology
has_related_synonym: muscle relaxants
in_subset: 3 STAR
imported from: chebi.owl

neuromuscular agent
type: Class
subclass of: drug
definition: A drug used for its actions on skeletal muscle.
id: CHEBI:51372
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

GABA agonist
type: Class
subclass of: GABA agent
definition: A drug that binds to and activates gamma-aminobutyric acid receptors.
id: CHEBI:51373
has_related_synonym: GABA agonists
has_related_synonym: GABA receptor agonist
has_related_synonym: GABA receptor agonists
has_obo_namespace: chebi_ontology
has_related_synonym: gamma-aminobutyric acid receptor agonist
has_related_synonym: gamma-aminobutyric acid receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

GABA agent
type: Class
subclass of: neurotransmitter agent
definition: A substance, such as agonists, antagonists, degradation or uptake inhibitors, depleters, precursors, and modulators of receptor function, used for its pharmacological actions on GABAergic systems.
id: CHEBI:51374
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

endothelin receptor antagonist
type: Class
subclass of: hormone antagonist
definition: A hormone antagonist that blocks endothelin receptors.
id: CHEBI:51451
has_related_synonym: ERA
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

endothelin A receptor antagonist
type: Class
subclass of: endothelin receptor antagonist
definition: A endothelin receptor antagonist is a drug which selectively blocks endothelin A receptors.
id: CHEBI:51452
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

partial prostacyclin agonist
type: Class
subclass of: vasodilator agent
subclass of: platelet aggregation inhibitor
definition: A compound which binds and activates the prostacyclin receptor IP1, but has only partial efficacy at the receptor relative to a full agonist.
id: CHEBI:51577
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

biochemical role
type: Class
subclass of: biological role
definition: A biological role played by the molecular entity or part thereof within a biochemical context.
id: CHEBI:52206
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

biophysical role
type: Class
subclass of: biological role
id: CHEBI:52208
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

aetiopathogenetic role
type: Class
subclass of: biological role
definition: A role played by the molecular entity or part thereof which causes the development of a pathological process.
id: CHEBI:52209
has_obo_namespace: chebi_ontology
has_related_synonym: etiopathogenetic agent
has_related_synonym: etiopathogenetic role
in_subset: 3 STAR
imported from: chebi.owl

pharmacological role
type: Class
subclass of: biological role
definition: A biological role which describes how a drug interacts within a biological system and how the interactions affect its medicinal properties.
id: CHEBI:52210
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

physiological role
type: Class
subclass of: biological role
id: CHEBI:52211
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

ligand
type: Class
subclass of: chemical role
definition: Any molecule or ion capable of binding to a central metal atom to form coordination complexes.
id: CHEBI:52214
database_cross_reference: Wikipedia:Ligand
has_obo_namespace: chebi_ontology
has_related_synonym: ligands
in_subset: 3 STAR
imported from: chebi.owl

photochemical role
type: Class
subclass of: chemical role
definition: A chemical role played by the molecular entity or part thereof in a photochemical process.
id: CHEBI:52215
has_obo_namespace: chebi_ontology
has_related_synonym: photochemical roles
in_subset: 3 STAR
imported from: chebi.owl

photobiochemical role
type: Class
subclass of: biochemical role
subclass of: photochemical role
definition: A role played by a molecular entity or part thereof in a photobiochemical process.
id: CHEBI:52216
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

pharmaceutical
type: Class
subclass of: application
definition: Any substance introduced into a living organism with therapeutic or diagnostic purpose.
has_alternative_id: CHEBI:33293
has_alternative_id: CHEBI:33294
id: CHEBI:52217
has_obo_namespace: chebi_ontology
has_related_synonym: farmaco
has_related_synonym: medicament
has_related_synonym: pharmaceuticals
in_subset: 3 STAR
imported from: chebi.owl

squaraine dye
type: Class
subclass of: fluorescent dye
definition: An organic dye characterized by an aromatic four-membered ring system derived from squaric acid.
id: CHEBI:52271
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

mitogen
type: Class
subclass of: biological role
definition: A chemical substance that encourages a cell to commence cell division, triggering mitosis.
id: CHEBI:52290
has_obo_namespace: chebi_ontology
has_related_synonym: mitogens
in_subset: 3 STAR
imported from: chebi.owl

sterol methyltransferase inhibitor
type: Class
subclass of: EC 2.1.1.* (methyltransferases) inhibitor
definition: An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of sterol methyltransferase.
id: CHEBI:52303
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 3.2.1.* (glycosidase) inhibitor
type: Class
subclass of: EC 3.2.* (glycosylase) inhibitor
definition: An EC 3.2.* (glycosylase) inhibitor that interferes with the action of any glycosidase (i.e. enzymes hydrolysing O- and S-glycosyl compounds, EC 3.2.1.*).
id: CHEBI:52424
has_alternative_id: CHEBI:76776
has_related_synonym: EC 3.2.1.* (glycosidase) inhibitors
has_related_synonym: EC 3.2.1.* inhibitor
has_related_synonym: EC 3.2.1.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: glycosidase (EC 3.2.1.*) inhibitor
has_related_synonym: glycosidase (EC 3.2.1.*) inhibitors
has_related_synonym: glycosidase inhibitor
has_related_synonym: glycosidase inhibitors
has_related_synonym: glycoside hydrolase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.2.1.18 (exo-alpha-sialidase) inhibitor
type: Class
subclass of: antiviral drug
subclass of: EC 3.2.1.* (glycosidase) inhibitor
definition: An antiviral drug targeted at influenza viruses. Its mode of action consists of blocking the function of the viral neuraminidase protein (EC 3.2.1.18), thus preventing the virus from budding from the host cell.
id: CHEBI:52425
has_related_synonym: EC 3.2.1.18 (exo-alpha-sialidase) inhibitors
has_related_synonym: EC 3.2.1.18 inhibitor
has_related_synonym: EC 3.2.1.18 inhibitors
has_related_synonym: N-acylneuraminate glycohydrolase inhibitor
has_related_synonym: N-acylneuraminate glycohydrolase inhibitors
has_related_synonym: acetylneuraminidase inhibitor
has_related_synonym: acetylneuraminidase inhibitors
has_related_synonym: acetylneuraminyl hydrolase inhibitor
has_related_synonym: acetylneuraminyl hydrolase inhibitors
has_related_synonym: alpha-neuraminidase inhibitor
has_related_synonym: alpha-neuraminidase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: exo-alpha-sialidase (EC 3.2.1.18) inhibitor
has_related_synonym: exo-alpha-sialidase (EC 3.2.1.18) inhibitors
has_related_synonym: exo-alpha-sialidase inhibitor
has_related_synonym: exo-alpha-sialidase inhibitors
has_related_synonym: neuraminidase inhibitor
has_related_synonym: neuraminidase inhibitors
has_related_synonym: sialidase inhibitor
has_related_synonym: sialidase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.1.26.13 (retroviral ribonuclease H) inhibitor
type: Class
subclass of: anti-HIV-1 agent
subclass of: EC 3.1.26.* (endoribonucleases producing 5'-phosphomonoesters) inhibitor
definition: An inhibitor of ribonuclease H (EC 3.1.26.13), an enzyme required for specific hydrolysis of the RNA strand of an RNA/DNA hybrid.
id: CHEBI:52629
has_related_synonym: EC 3.1.26.13 (retroviral ribonuclease H) inhibitors
has_related_synonym: EC 3.1.26.13 inhibitor
has_related_synonym: EC 3.1.26.13 inhibitors
has_related_synonym: HIV RNase H inhibitor
has_related_synonym: HIV RNase H inhibitors
has_related_synonym: HIV-1 RNase H inhibitor
has_related_synonym: HIV-1 RNase H inhibitors
has_related_synonym: HIV-1 ribonuclease H inhibitor
has_related_synonym: HIV-1 ribonuclease H inhibitors
has_related_synonym: RT/RNase H inhibitor
has_related_synonym: RT/RNase H inhibitors
database_cross_reference: Wikipedia:Retroviral_ribonuclease_H
has_obo_namespace: chebi_ontology
has_related_synonym: retroviral reverse transcriptase RNaseH inhibitor
has_related_synonym: retroviral reverse transcriptase RNaseH inhibitors
has_related_synonym: retroviral ribonuclease H (EC 3.1.26.13) inhibitor
has_related_synonym: retroviral ribonuclease H (EC 3.1.26.13) inhibitors
has_related_synonym: retroviral ribonuclease H inhibitor
in_subset: 3 STAR
imported from: chebi.owl

proteasome inhibitor
type: Class
subclass of: drug
definition: A drug that blocks the action of proteasomes, cellular complexes that break down proteins.
id: CHEBI:52726
has_obo_namespace: chebi_ontology
has_related_synonym: proteasome inhibitors
in_subset: 3 STAR
imported from: chebi.owl

phosphate protecting group
type: Class
subclass of: protecting group
definition: A group that serves to protect a phosphate group in the context of a synthesis.
id: CHEBI:52941
has_obo_namespace: chebi_ontology
has_related_synonym: phosphate protecting groups
in_subset: 3 STAR
imported from: chebi.owl

carboxylic acid protecting group
type: Class
subclass of: protecting group
definition: A group that serves to protect a carboxylic acid function in the context of a synthesis.
id: CHEBI:52943
has_related_synonym: carboxylic acid protecting groups
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

epitope
type: Class
subclass of: biological role
id: CHEBI:53000
definition: The biological role played by a material entity when bound by a receptor of the adaptive immune system. Specific site on an antigen to which an antibody binds.
has_related_synonym: antigenic determinant
has_obo_namespace: chebi_ontology
has_related_synonym: epitope function
has_related_synonym: epitope role
in_subset: 3 STAR
imported from: chebi.owl

adenosine A2A receptor antagonist
type: Class
subclass of: adenosine receptor antagonist
definition: An antagonist at the A2A receptor.
id: CHEBI:53121
database_cross_reference: Wikipedia:Adenosine_A2A_receptor
has_related_synonym: adenosine A2A receptor antagonists
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

P2Y2 receptor agonist
type: Class
subclass of: agonist
definition: A compound that exhibits agonist activity at the P2Y2 receptor.
id: CHEBI:53142
has_related_synonym: P2Y2 receptor agonists
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

tissue adhesive
type: Class
subclass of: biological role
definition: A substance used to cause adherence of tissue to tissue or tissue to non-tissue surfaces, as for prostheses.
id: CHEBI:53337
has_obo_namespace: chebi_ontology
has_related_synonym: tissue adhesives
in_subset: 3 STAR
imported from: chebi.owl

GHB receptor agonist
type: Class
subclass of: neurotransmitter agent
definition: A drug that binds to and activates gamma-hydroxybutyric acid receptors.
id: CHEBI:53353
has_related_synonym: GHB receptor agonists
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

chain carrier
type: Class
subclass of: chemical role
id: CHEBI:53431
definition: The role played by a molecular entity, such as an atom or free radical, which is involved in chain-propagating reactions.
has_related_synonym: chain carriers
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

topoisomerase IV inhibitor
type: Class
subclass of: topoisomerase inhibitor
definition: A topoisomerase inhibitor that inhibits DNA topoisomerase IV, which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands.
id: CHEBI:53559
has_obo_namespace: chebi_ontology
has_related_synonym: topoisomerase IV inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.4.3.22 (diamine oxidase) inhibitor
type: Class
subclass of: EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor
definition: An EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor that interferes with the action of diamine oxidase (EC 1.4.3.22).
id: CHEBI:53659
has_related_synonym: EC 1.4.3.22 (diamine oxidase) inhibitors
has_related_synonym: EC 1.4.3.22 inhibitor
has_related_synonym: EC 1.4.3.22 inhibitors
database_cross_reference: Wikipedia:Diamine_oxidase
has_obo_namespace: chebi_ontology
has_related_synonym: diamine oxidase (EC 1.4.3.22) inhibitor
has_related_synonym: diamine oxidase (EC 1.4.3.22) inhibitors
has_related_synonym: diamine oxidase inhibitor
has_related_synonym: diamine oxidase inhibitors
has_related_synonym: histaminase inhibitor
has_related_synonym: histaminase inhibitors
has_related_synonym: histamine:oxygen oxidoreductase (deaminating) inhibitor
has_related_synonym: histamine:oxygen oxidoreductase (deaminating) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.1.1.205 (IMP dehydrogenase) inhibitor
type: Class
subclass of: EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor
definition: An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of IMP dehydrogenase (EC 1.1.1.205), so blocking de novo biosynthesis of purine nucleotides.
id: CHEBI:53746
has_related_synonym: EC 1.1.1.205 (IMP dehydrogenase) inhibitors
has_related_synonym: EC 1.1.1.205 inhibitor
has_related_synonym: EC 1.1.1.205 inhibitors
has_related_synonym: IMP dehydrogenase (EC 1.1.1.205) inhibitor
has_related_synonym: IMP dehydrogenase (EC 1.1.1.205) inhibitors
has_related_synonym: IMP dehydrogenase inhibitor
has_related_synonym: IMP dehydrogenase inhibitors
has_related_synonym: IMP oxidoreductase inhibitor
has_related_synonym: IMP oxidoreductase inhibitors
has_related_synonym: IMP:NAD(+) oxidoreductase inhibitor
has_related_synonym: IMP:NAD(+) oxidoreductase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inosinate dehydrogenase inhibitor
has_related_synonym: inosinate dehydrogenase inhibitors
has_related_synonym: inosine 5'-monophosphate dehydrogenase inhibitors
has_related_synonym: inosine monophosphate dehydrogenase inhibitor
has_related_synonym: inosine monophosphate dehydrogenase inhibitors
has_related_synonym: inosine monophosphate oxidoreductase inhibitor
has_related_synonym: inosine monophosphate oxidoreductase inhibitors
has_related_synonym: inosinic acid dehydrogenase inhibitor
has_related_synonym: inosinic acid dehydrogenase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

HIV-1 reverse transcriptase inhibitor
type: Class
subclass of: EC 3.1.26.13 (retroviral ribonuclease H) inhibitor
subclass of: anti-HIV-1 agent
definition: An entity which inhibits the activity of HIV-1 reverse transcriptase.
id: CHEBI:53756
has_related_synonym: HIV-1 reverse transcriptase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: reverse transcriptase inhibitor
has_related_synonym: reverse transcriptase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

antispasmodic drug
type: Class
subclass of: muscle relaxant
definition: A drug that suppresses spasms. These are usually caused by smooth muscle contraction, especially in tubular organs. The effect is to prevent spasms of the stomach, intestine or urinary bladder.
id: CHEBI:53784
has_related_synonym: antispasmodics
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

mu-opioid receptor agonist
type: Class
subclass of: mu-opioid agent
subclass of: opioid receptor agonist
definition: A compound that exhibits agonist activity at the mu-opioid receptor.
has_alternative_id: CHEBI:50136
id: CHEBI:55322
has_obo_namespace: chebi_ontology
has_related_synonym: mu opioid agonist
has_related_synonym: mu-opioid agonists
has_related_synonym: mu-opioid receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

antidiarrhoeal drug
type: Class
subclass of: gastrointestinal drug
definition: Any drug found useful in the symptomatic treatment of diarrhoea.
id: CHEBI:55323
has_related_synonym: antidiarrheal
has_related_synonym: antidiarrheal agent
has_related_synonym: antidiarrheal agents
has_related_synonym: antidiarrheal drug
has_related_synonym: antidiarrheal drugs
has_related_synonym: antidiarrheals
has_related_synonym: antidiarrhoeal
has_related_synonym: antidiarrhoeal agent
has_related_synonym: antidiarrhoeal agents
has_related_synonym: antidiarrhoeal drugs
has_related_synonym: antidiarrhoeals
has_related_synonym: antiperistaltic
has_related_synonym: antiperistaltic agent
has_related_synonym: antiperistaltic agents
has_related_synonym: antiperistaltic drug
has_related_synonym: antiperistaltic drugs
has_related_synonym: antiperistaltics
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

gastrointestinal drug
type: Class
subclass of: drug
definition: A drug used for its effects on the gastrointestinal system, e.g. controlling gastric acidity, regulating gastrointestinal motility and water flow, and improving digestion.
id: CHEBI:55324
has_obo_namespace: chebi_ontology
has_related_synonym: gastrointestinal agent
has_related_synonym: gastrointestinal agents
has_related_synonym: gastrointestinal drugs
in_subset: 3 STAR
imported from: chebi.owl

vitamin K antagonist
type: Class
subclass of: antagonist
definition: A class of anticoagulants which act by inhibiting the action of vitamin K.
id: CHEBI:55347
has_obo_namespace: chebi_ontology
has_related_synonym: vitamin K antagonists
in_subset: 3 STAR
imported from: chebi.owl

neurokinin-1 receptor antagonist
type: Class
subclass of: antagonist
definition: An antagonist at the neurokinin-1 receptor.
id: CHEBI:55350
has_related_synonym: NK-1 receptor antagonist
has_related_synonym: NK-1 receptor antagonists
has_related_synonym: NK1 receptor antagonist
has_related_synonym: NK1 receptor antagonists
has_obo_namespace: chebi_ontology
has_related_synonym: neurokinin-1 receptor antagonists
in_subset: 3 STAR
imported from: chebi.owl

substance P receptor antagonist
type: Class
subclass of: antagonist
definition: An antagonist at the substance P receptor.
id: CHEBI:55351
has_obo_namespace: chebi_ontology
has_related_synonym: substance P receptor antagonists
in_subset: 3 STAR
imported from: chebi.owl

antiseborrheic
type: Class
subclass of: dermatologic drug
definition: A drug or agent applied to the skin to control seborrhea or seborrheic dermatitis.
id: CHEBI:59010
has_related_synonym: antiseborrheic agent
has_related_synonym: antiseborrheic agents
has_related_synonym: antiseborrheic drug
has_related_synonym: antiseborrheics
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 6.3.2.* (acid--D-amino-acid ligase) inhibitor
type: Class
subclass of: EC 6.3.* (C-N bond-forming ligase) inhibitor
definition: Any inhibitor of an acid--D-amino-acid ligase (EC 6.3.2.*).
id: CHEBI:59105
has_related_synonym: EC 6.3.2.* (acid--D-amino-acid ligase (peptide synthase)) inhibitor
has_related_synonym: EC 6.3.2.* (acid--D-amino-acid ligase (peptide synthase)) inhibitors
has_related_synonym: EC 6.3.2.* (acid--D-amino-acid ligase) inhibitors
has_related_synonym: EC 6.3.2.* (acid--amino-acid ligase) inhibitor
has_related_synonym: EC 6.3.2.* (acid--amino-acid ligase) inhibitors
has_related_synonym: EC 6.3.2.* [acid--D-amino-acid ligase (peptide synthase)] inhibitor
has_related_synonym: EC 6.3.2.* [acid--D-amino-acid ligase (peptide synthase)] inhibitors
has_related_synonym: EC 6.3.2.* inhibitor
has_related_synonym: EC 6.3.2.* inhibitors
has_related_synonym: acid--amino-acid ligase inhibitor
has_related_synonym: acid--amino-acid ligase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: peptide synthase inhibitor
has_related_synonym: peptide synthase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.24.* (metalloendopeptidase) inhibitor
type: Class
subclass of: protease inhibitor
subclass of: EC 3.4.* (hydrolases acting on peptide bond) inhibitor
definition: Any EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes with the activity of a metalloendopeptidase (EC 3.4.24.*).
id: CHEBI:59107
has_alternative_id: CHEBI:76786
has_related_synonym: EC 3.4.24.* (metalloendopeptidase) inhibitors
has_related_synonym: EC 3.4.24.* inhibitor
has_related_synonym: EC 3.4.24.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of metalloendopeptidases
has_related_synonym: inhibitor of metalloendopeptidases (EC 3.4.24.*)
has_related_synonym: inhibitors of metalloendopeptidases
has_related_synonym: inhibitors of metalloendopeptidases (EC 3.4.24.*)
has_related_synonym: metalloendopeptidase (EC 3.4.24.*) inhibitor
has_related_synonym: metalloendopeptidase (EC 3.4.24.*) inhibitors
has_related_synonym: metalloendopeptidase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

antigen
type: Class
subclass of: biological role
definition: Any substance that stimulates an immune response in the body, such as through antibody production or by presentation to a T-cell receptor after binding to a major histocompability complex (MHC).
id: CHEBI:59132
has_related_synonym: antigens
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

biomarker
type: Class
subclass of: indicator
definition: A substance used as an indicator of a biological state.
id: CHEBI:59163
has_related_synonym: biological marker
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

hapten
type: Class
subclass of: biological role
definition: Any substance capable of eliciting an immune response only when attached to a large carrier such as a protein. Examples include dinitrophenols; oligosaccharides; peptides; and heavy metals.
id: CHEBI:59174
database_cross_reference: PMID:17875790
database_cross_reference: PMID:17986299
database_cross_reference: PMID:19101624
database_cross_reference: PMID:291959
database_cross_reference: PMID:3782019
has_obo_namespace: chebi_ontology
has_related_synonym: haptens
in_subset: 3 STAR
imported from: chebi.owl

GnRH antagonist
type: Class
subclass of: hormone antagonist
definition: A chemical substance which inhibits the function of gonadotrophin-releasing hormone (GnRH).
id: CHEBI:59229
has_related_synonym: GnRH antagonists
has_obo_namespace: chebi_ontology
has_related_synonym: gonadotrophin-releasing hormone antagonist
has_related_synonym: gonadotrophin-releasing hormone antagonists
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.21.* (serine endopeptidase) inhibitor
type: Class
subclass of: EC 3.4.* (hydrolases acting on peptide bond) inhibitor
definition: Any EC 3.4.* (hydrolases acting on peptide bond) inhibitor that inhibits the activity of a serine endopeptidase (EC 3.4.21.*).
id: CHEBI:5924
has_related_synonym: EC 3.4.21.* (serine endopeptidase) inhibitors
has_related_synonym: EC 3.4.21.* inhibitor
has_related_synonym: EC 3.4.21.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of serine endopeptidase (EC 3.4.21.*)
has_related_synonym: inhibitor of serine endopeptidase (EC 3.4.21.*)s
has_related_synonym: serine endopeptidase inhibitor
has_related_synonym: serine endopeptidase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

kappa-opioid receptor agonist
type: Class
subclass of: kappa-opioid agent
subclass of: opioid receptor agonist
definition: A compound that exhibits agonist activity at the kappa-opioid receptor.
id: CHEBI:59282
has_obo_namespace: chebi_ontology
has_related_synonym: kappa-opioid agonist
has_related_synonym: kappa-opioid receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

delta-opioid receptor antagonist
type: Class
subclass of: delta-opioid agent
subclass of: opioid receptor antagonist
definition: Any compound that exhibits antagonist activity at the delta-opioid receptor.
id: CHEBI:59283
has_obo_namespace: chebi_ontology
has_related_synonym: delta-opioid antagonist
has_related_synonym: delta-opioid antagonists
in_subset: 3 STAR
imported from: chebi.owl

EC 1.14.13.132 (squalene monooxygenase) inhibitor
type: Class
subclass of: EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor
definition: An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of squalene monooxygenase (EC 1.14.13.132).
id: CHEBI:59285
has_related_synonym: EC 1.14.13.132 (squalene monooxygenase) inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: squalene 2,3-oxidocyclase inhibitor
has_related_synonym: squalene 2,3-oxidocyclase inhibitors
has_related_synonym: squalene epoxidase inhibitor
has_related_synonym: squalene epoxidase inhibitors
has_related_synonym: squalene hydroxylase inhibitor
has_related_synonym: squalene hydroxylase inhibitors
has_related_synonym: squalene monooxygenase (EC 1.14.13.132) inhibitor
has_related_synonym: squalene monooxygenase (EC 1.14.13.132) inhibitors
has_related_synonym: squalene monooxygenase inhibitor
has_related_synonym: squalene monooxygenase inhibitors
has_related_synonym: squalene oxydocyclase inhibitor
has_related_synonym: squalene oxydocyclase inhibitors
has_related_synonym: squalene-2,3-epoxidase inhibitor
has_related_synonym: squalene-2,3-epoxidase inhibitors
has_related_synonym: squalene-2,3-epoxide cyclase inhibitor
has_related_synonym: squalene-2,3-epoxide cyclase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 4.1.1.28 (aromatic-L-amino-acid decarboxylase) inhibitor
type: Class
subclass of: EC 4.1.1.* (carboxy-lyase) inhibitor
has_related_synonym: 5-hydroxytryptophan decarboxylase inhibitor
has_related_synonym: 5-hydroxytryptophan decarboxylase inhibitors
definition: An EC 4.1.1.* (carboxy-lyase) inhibitor that interferes with the action of aromatic-L-amino-acid decarboxylase (EC 4.1.1.28).
id: CHEBI:59321
has_related_synonym: DOPA decarboxylase inhibitor
has_related_synonym: DOPA decarboxylase inhibitors
has_related_synonym: EC 4.1.1.28 (aromatic-L-amino-acid decarboxylase) inhibitors
has_related_synonym: EC 4.1.1.28 inhibitor
has_related_synonym: EC 4.1.1.28 inhibitors
has_related_synonym: L-DOPA decarboxylase inhibitor
has_related_synonym: L-DOPA decarboxylase inhibitors
has_related_synonym: aromatic amino acid decarboxylase inhibitor
has_related_synonym: aromatic amino acid decarboxylase inhibitors
has_related_synonym: aromatic-L-amino-acid decarboxylase (EC 4.1.1.28) inhibitor
has_related_synonym: aromatic-L-amino-acid decarboxylase (EC 4.1.1.28) inhibitors
has_related_synonym: aromatic-L-amino-acid decarboxylase inhibitor
has_related_synonym: aromatic-L-amino-acid decarboxylase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: hydroxytryptophan decarboxylase inhibitor
has_related_synonym: hydroxytryptophan decarboxylase inhibitors
has_related_synonym: tryptophan decarboxylase inhibitor
has_related_synonym: tryptophan decarboxylase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.13.* (dipeptidase) inhibitor
type: Class
subclass of: EC 3.4.* (hydrolases acting on peptide bond) inhibitor
definition: Any EC 3.4.* (hydrolases acting on peptide bond) inhibitor that inhibits the action of a dipeptidase (EC 3.4.13.*).
id: CHEBI:59499
has_related_synonym: EC 3.4.13.* (dipeptidase) inhibitors
has_related_synonym: EC 3.4.13.* inhibitor
has_related_synonym: EC 3.4.13.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: dipeptidase inhibitor
has_related_synonym: dipeptidase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

DNA synthesis inhibitor
type: Class
subclass of: pathway inhibitor
definition: Any substance that inhibits the synthesis of DNA.
id: CHEBI:59517
has_related_synonym: DNA synthesis inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

phosphoantigen
type: Class
subclass of: antigen
definition: Any antigen that is a phosphorylated microbial metabolite which activates an immune response in humans.
id: CHEBI:59544
has_obo_namespace: chebi_ontology
has_related_synonym: phosphoantigens
in_subset: 3 STAR
imported from: chebi.owl

EC 2.3.1.50 (serine C-palmitoyltransferase) inhibitor
type: Class
subclass of: EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor
has_related_synonym: 3-oxosphinganine synthetase inhibitor
has_related_synonym: 3-oxosphinganine synthetase inhibitors
definition: An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of serine palmitoyltransferase (EC 2.3.1.50).
id: CHEBI:59647
has_related_synonym: EC 2.3.1.50 (serine C-palmitoyltransferase) inhibitors
has_related_synonym: EC 2.3.1.50 inhibitor
has_related_synonym: EC 2.3.1.50 inhibitors
has_related_synonym: SPT inhibitor
has_related_synonym: SPT inhibitors
database_cross_reference: Wikipedia:Serine_C-palmitoyltransferase
has_related_synonym: acyl-CoA:serine C-2 acyltransferase (decarboxylating) inhibitor
has_related_synonym: acyl-CoA:serine C-2 acyltransferase (decarboxylating) inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) inhibitor
has_related_synonym: palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) inhibitors
has_related_synonym: serine C-palmitoyltransferase (EC 2.3.1.50) inhibitor
has_related_synonym: serine C-palmitoyltransferase (EC 2.3.1.50) inhibitors
has_related_synonym: serine C-palmitoyltransferase inhibitor
has_related_synonym: serine C-palmitoyltransferase inhibitors
has_related_synonym: serine palmitoyltransferase inhibitor
has_related_synonym: serine palmitoyltransferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.4.1.16 (chitin synthase) inhibitor
type: Class
subclass of: EC 2.4.1.* (hexosyltransferase) inhibitor
definition: A EC 2.4.1.* (hexosyltransferase) inhibitor that inhibits the action of chitin synthase (EC 2.4.1.16).
id: CHEBI:59672
has_related_synonym: EC 2.4.1.16 (chitin synthase) inhibitors
has_related_synonym: EC 2.4.1.16 inhibitor
has_related_synonym: EC 2.4.1.16 inhibitors
has_related_synonym: UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyl-transferase inhibitor
has_related_synonym: UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyl-transferase inhibitors
database_cross_reference: Wikipedia:Chitin_synthase
has_obo_namespace: chebi_ontology
has_related_synonym: chitin synthase (EC 2.4.1.16) inhibitor
has_related_synonym: chitin synthase (EC 2.4.1.16) inhibitors
has_related_synonym: chitin synthase inhibitor
has_related_synonym: chitin synthase inhibitors
has_related_synonym: chitin synthesis inhibitor
has_related_synonym: chitin synthesis inhibitors
has_related_synonym: chitin synthetase inhibitor
has_related_synonym: chitin synthetase inhibitors
has_related_synonym: chitin-UDP N-acetylglucosaminyltransferase inhibitor
has_related_synonym: chitin-UDP N-acetylglucosaminyltransferase inhibitors
has_related_synonym: chitin-UDP acetyl-glucosaminyl transferase inhibitor
has_related_synonym: chitin-UDP acetyl-glucosaminyl transferase inhibitors
has_related_synonym: chitin-uridine diphosphate acetylglucosaminyltransferase inhibitor
has_related_synonym: chitin-uridine diphosphate acetylglucosaminyltransferase inhibitors
has_related_synonym: trans-N-acetylglucosaminosylase inhibitor
has_related_synonym: trans-N-acetylglucosaminosylase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

vasopressin receptor antagonist
type: Class
subclass of: hormone antagonist
definition: Any drug which blocks vasopressin receptors.
id: CHEBI:59680
has_related_synonym: antidiuretic hormone inhibitor
has_related_synonym: antidiuretic hormone inhibitors
has_related_synonym: arginine vasopressin receptor antagonist
has_related_synonym: arginine vasopressin receptor antagonists
has_related_synonym: argipressin receptor antagonist
has_related_synonym: argipressin receptor antagonists
has_obo_namespace: chebi_ontology
has_related_synonym: vasopressin receptor antagonists
in_subset: 3 STAR
imported from: chebi.owl

antipruritic drug
type: Class
subclass of: dermatologic drug
definition: A drug, usually applied topically, that relieves pruritus (itching).
id: CHEBI:59683
has_related_synonym: anti-itching drug
has_related_synonym: anti-itching drugs
has_related_synonym: antipruritic agent
has_related_synonym: antipruritic agents
has_related_synonym: antipruritic drugs
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

vasopressin receptor agonist
type: Class
subclass of: hormone agonist
definition: Any drug which binds to vasopressin receptors and triggers a response.
id: CHEBI:59727
has_related_synonym: antidiuretic hormone agonist
has_related_synonym: antidiuretic hormone agonists
has_related_synonym: arginine vasopressin receptor agonist
has_related_synonym: arginine vasopressin receptor agonists
has_related_synonym: argipressin receptor agonist
has_related_synonym: argipressin receptor agonists
has_obo_namespace: chebi_ontology
has_related_synonym: vasopressin receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

electrophilic reagent
type: Class
subclass of: reagent
subclass of: Lewis acid
definition: A reagent that forms a bond to its reaction partner (the nucleophile) by accepting both bonding electrons from that reaction partner.
id: CHEBI:59739
has_obo_namespace: chebi_ontology
has_related_synonym: electrophile
has_related_synonym: electrophiles
has_related_synonym: electrophilic reagents
in_subset: 3 STAR
imported from: chebi.owl

nucleophilic reagent
type: Class
subclass of: reagent
subclass of: Lewis base
definition: A reagent that forms a bond to its reaction partner (the electrophile) by donating both bonding electrons.
id: CHEBI:59740
has_obo_namespace: chebi_ontology
has_related_synonym: nucleophile
has_related_synonym: nucleophiles
has_related_synonym: nucleophilic reagents
in_subset: 3 STAR
imported from: chebi.owl

chromatographic reagent
type: Class
subclass of: reagent
definition: A reagent used to improve selectivity in chromatographic analyses or separations, e.g. by formation of a derivative or by modification of the mobile phase.
id: CHEBI:59745
has_obo_namespace: chebi_ontology
has_related_synonym: derivatising reagents
has_related_synonym: derivatizing reagent
has_related_synonym: derivatizing reagents
in_subset: 3 STAR
imported from: chebi.owl

bolaamphiphile
type: Class
subclass of: surfactant
definition: A surfactant molecule with hydrophilic groups at both ends of a hydrophobic hydrocarbon chain
id: CHEBI:59752
has_related_synonym: alpha-omega-type surfactant
has_related_synonym: bolaamphiphiles
has_related_synonym: bolaform surfactant
has_related_synonym: bolaphile
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

progestin
type: Class
subclass of: progestogen
definition: A synthetic progestogen.
id: CHEBI:59826
database_cross_reference: Wikipedia:Progestin
has_obo_namespace: chebi_ontology
has_related_synonym: progestins
in_subset: 3 STAR
imported from: chebi.owl

antihyperplasia drug
type: Class
subclass of: drug
definition: A drug used for the treatment of hyperplasia (increaced cell production within an organ or tissue).
id: CHEBI:59844
has_related_synonym: antihypergenesis drug
has_related_synonym: antihypergenesis drugs
has_related_synonym: antihyperplasia drugs
has_related_synonym: antihyperplastic
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

depigmentation drug
type: Class
subclass of: drug
definition: Any drug used to depigment skin, normally by decreasing the excretion of melanin from melanocytes.
id: CHEBI:59864
has_obo_namespace: chebi_ontology
has_related_synonym: depigmentation agent
has_related_synonym: depigmentation agents
has_related_synonym: depigmentation drugs
has_related_synonym: depigmentor
has_related_synonym: depigmentors
in_subset: 3 STAR
imported from: chebi.owl

HIV fusion inhibitor
type: Class
subclass of: antiviral drug
subclass of: anti-HIV agent
definition: A drug which interferes with the binding, fusion and entry of an HIV virion to a human cell. By blocking this step in HIV's replication cycle, such agents slow the progression from HIV infection to AIDS.
id: CHEBI:59886
has_related_synonym: HIV entry inhibitor
has_related_synonym: HIV entry inhibitors
has_related_synonym: HIV fusion inhibitors
database_cross_reference: PMID:22470838
database_cross_reference: Wikipedia:Entry_inhibitor
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor
type: Class
subclass of: antiviral agent
subclass of: DNA polymerase inhibitor
definition: A DNA polymerase inhibitor that interferes with the activity of reverse transcriptase, EC 2.7.7.49, a viral DNA polymerase enzyme that retroviruses need in order to reproduce.
id: CHEBI:59897
has_related_synonym: DNA nucleotidyltransferase (RNA-directed) inhibitor
has_related_synonym: DNA nucleotidyltransferase (RNA-directed) inhibitors
has_related_synonym: EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitors
has_related_synonym: EC 2.7.7.49 inhibitor
has_related_synonym: EC 2.7.7.49 inhibitors
has_related_synonym: RNA revertase inhibitor
has_related_synonym: RNA revertase inhibitors
has_related_synonym: RNA-dependent DNA polymerase inhibitor
has_related_synonym: RNA-dependent DNA polymerase inhibitors
has_related_synonym: RNA-dependent deoxyribonucleate nucleotidyltransferase inhibitor
has_related_synonym: RNA-dependent deoxyribonucleate nucleotidyltransferase inhibitors
has_related_synonym: RNA-directed DNA polymerase (EC 2.7.7.49) inhibitor
has_related_synonym: RNA-directed DNA polymerase (EC 2.7.7.49) inhibitors
has_related_synonym: RNA-directed DNA polymerase inhibitor
has_related_synonym: RNA-directed DNA polymerase inhibitors
has_related_synonym: RNA-instructed DNA polymerase inhibitor
has_related_synonym: RNA-instructed DNA polymerase inhibitors
has_related_synonym: RT inhibitor
has_related_synonym: RT inhibitors
database_cross_reference: Wikipedia:Reverse-transcriptase_inhibitor
has_obo_namespace: chebi_ontology
has_related_synonym: deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (RNA-directed) inhibitor
has_related_synonym: deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (RNA-directed) inhibitors
has_related_synonym: reverse transcriptase inhibitor
has_related_synonym: reverse transcriptase inhibitors
has_related_synonym: revertase inhibitor
has_related_synonym: revertase inhibitors
has_related_synonym: telomerase inhibitor
has_related_synonym: telomerase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

amphiphile
type: Class
subclass of: surfactant
definition: A surfactant molecule possessing both hydrophilic and lipophilic properties.
id: CHEBI:59941
has_related_synonym: amphiphiles
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 1.14.18.1 (tyrosinase) inhibitor
type: Class
subclass of: EC 1.14.18.* (oxidoreductase acting on paired donors, miscellaneous compound as one donor, incorporating 1 atom of oxygen) inhibitor
definition: Any EC 1.14.18.* (oxidoreductase acting on paired donors, miscellaneous compound as one donor, incorporating 1 atom of oxygen) inhibitor that interferes with the action of tyrosinase (monophenol monooxygenase), EC 1.14.18.1, an enzyme that catalyses the oxidation of phenols (such as tyrosine) and is widespread in plants and animals.
id: CHEBI:59997
has_related_synonym: EC 1.14.18.1 (tyrosinase) inhibitors
has_related_synonym: EC 1.14.18.1 inhibitor
has_related_synonym: EC 1.14.18.1 inhibitors
has_related_synonym: L-tyrosine,L-dopa:oxygen oxidoreductase inhibitor
has_related_synonym: L-tyrosine,L-dopa:oxygen oxidoreductase inhibitors
has_related_synonym: NN-acetyl-6-hydroxytryptophan oxidase inhibitor
has_related_synonym: NN-acetyl-6-hydroxytryptophan oxidase inhibitors
has_related_synonym: O-diphenol:O2 oxidoreductase inhibitor
has_related_synonym: O-diphenol:O2 oxidoreductase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: cresolase inhibitor
has_related_synonym: cresolase inhibitors
has_related_synonym: monophenol dihydroxyphenylalanine:oxygen oxidoreductase inhibitor
has_related_synonym: monophenol dihydroxyphenylalanine:oxygen oxidoreductase inhibitors
has_related_synonym: monophenol monooxidase inhibitor
has_related_synonym: monophenol monooxidase inhibitors
has_related_synonym: monophenol monooxygenase inhibitor
has_related_synonym: monophenol monooxygenase inhibitors
has_related_synonym: monophenol oxidase inhibitor
has_related_synonym: monophenol oxidase inhibitors
has_related_synonym: monophenol, dihydroxy-L-phenylalanine oxygen oxidoreductase inhibitor
has_related_synonym: monophenol, dihydroxy-L-phenylalanine oxygen oxidoreductase inhibitors
has_related_synonym: monophenolase inhibitor
has_related_synonym: monophenolase inhibitors
has_related_synonym: phenol oxidase inhibitor
has_related_synonym: phenol oxidase inhibitors
has_related_synonym: phenolase inhibitor
has_related_synonym: phenolase inhibitors
has_related_synonym: tyrosinase (EC 1.14.18.1) inhibitor
has_related_synonym: tyrosinase (EC 1.14.18.1) inhibitors
has_related_synonym: tyrosinase inhibitor
has_related_synonym: tyrosinase inhibitors
has_related_synonym: tyrosine-dopa oxidase inhibitor
has_related_synonym: tyrosine-dopa oxidase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor
type: Class
subclass of: EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor
has_related_synonym: ATP phosphohydrolase (Ca(2+)-transporting) inhibitor
has_related_synonym: ATP phosphohydrolase (Ca(2+)-transporting) inhibitors
definition: An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of Ca(2+)-transporting ATPase (EC 3.6.3.8).
id: CHEBI:60186
has_related_synonym: Ca(2+)-pumping ATPase inhibitor
has_related_synonym: Ca(2+)-pumping ATPase inhibitors
has_related_synonym: Ca(2+)-transporting ATPase (EC 3.6.3.8) inhibitor
has_related_synonym: Ca(2+)-transporting ATPase (EC 3.6.3.8) inhibitors
has_related_synonym: Ca(2+)-transporting ATPase inhibitor
has_related_synonym: Ca(2+)-transporting ATPase inhibitors
has_related_synonym: EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitors
has_related_synonym: SERCA inhibitor
has_related_synonym: SERCA inhibitors
database_cross_reference: Wikipedia:Ca(2%2B)-transporting_atpase
has_related_synonym: calcium pump inhibitor
has_related_synonym: calcium pump inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: plasma membrane Ca-ATPase inhibitor
has_related_synonym: plasma membrane Ca-ATPase inhibitors
has_related_synonym: sarco(endo)plasmic reticulum Ca(2+)-ATPase inhibitor
has_related_synonym: sarco(endo)plasmic reticulum Ca(2+)-ATPase inhibitors
has_related_synonym: sarcoplasmic reticulum ATPase inhibitor
has_related_synonym: sarcoplasmic reticulum ATPase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

mimotope
type: Class
subclass of: biological role
definition: Any macromolecule whose structure mimics that of an epitope. When applied to immunisation, a mimotope induces the desired antibody specificities exclusively based on the principle of molecular mimicry.
id: CHEBI:60218
database_cross_reference: PMID:17825923
database_cross_reference: PMID:18228183
database_cross_reference: PMID:19344285
has_related_synonym: antigenic determinant mimic
has_obo_namespace: chebi_ontology
has_related_synonym: epitope mimic
has_related_synonym: mimeotope
has_related_synonym: mimeotope function
has_related_synonym: mimeotope role
has_related_synonym: mimetope
has_related_synonym: mimotope function
has_related_synonym: mimotope role
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.* (hydrolases acting on peptide bond) inhibitor
type: Class
subclass of: EC 3.* (hydrolase) inhibitor
definition: A hydrolase inhibitor that interferes with the action of any hydrolase acting on peptide bonds (peptidase), EC 3.4.*.*).
id: CHEBI:60258
has_alternative_id: CHEBI:76763
has_related_synonym: EC 3.4.* (hydrolase acting on peptide bond) inhibitor
has_related_synonym: EC 3.4.* (hydrolase acting on peptide bonds) inhibitors
has_related_synonym: EC 3.4.* (hydrolases acting on peptide bond) inhibitors
has_related_synonym: EC 3.4.* (peptidase) inhibitor
has_related_synonym: EC 3.4.* (peptidase) inhibitors
has_related_synonym: EC 3.4.* inhibitor
has_related_synonym: EC 3.4.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of hydrolases acting on peptide bond (EC 3.4.*)
has_related_synonym: inhibitors of hydrolases acting on peptide bond (EC 3.4.*)
has_related_synonym: peptidase inhibitors
has_related_synonym: protease inhibitor
has_related_synonym: protease inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.5.1.2 (glutaminase) inhibitor
type: Class
subclass of: EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor
definition: Any EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the activity of a glutaminase (EC 3.5.1.2) and thus the generation of glutamate from glutamine.
id: CHEBI:60280
has_related_synonym: EC 3.5.1.2 (glutaminase) inhibitors
has_related_synonym: EC 3.5.1.2 inhibitor
has_related_synonym: EC 3.5.1.2 inhibitors
has_related_synonym: L-glutaminase inhibitor
has_related_synonym: L-glutaminase inhibitors
has_related_synonym: L-glutamine amidohydrolase inhibitor
has_related_synonym: L-glutamine amidohydrolase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: glutaminase (EC 3.5.1.2) inhibitor
has_related_synonym: glutaminase (EC 3.5.1.2) inhibitors
has_related_synonym: glutaminase I inhibitor
has_related_synonym: glutaminase I inhibitors
has_related_synonym: glutaminase inhibitor
has_related_synonym: glutaminase inhibitors
has_related_synonym: glutamine aminohydrolase inhibitor
has_related_synonym: glutamine aminohydrolase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

thyroid hormone
type: Class
subclass of: hormone
definition: Any hormone produced by the thyroid gland
id: CHEBI:60311
has_obo_namespace: chebi_ontology
has_related_synonym: thyroid hormones
in_subset: 3 STAR
imported from: chebi.owl

phenoxy herbicide
type: Class
subclass of: herbicide
definition: Any member of the class of herbicides whose members contain a phenoxy or substituted phenoxy group.
id: CHEBI:60575
database_cross_reference: Wikipedia:Phenoxy_herbicide
has_obo_namespace: chebi_ontology
has_related_synonym: phenoxy herbicides
in_subset: 3 STAR
imported from: chebi.owl

opioid agent
type: Class
subclass of: neurotransmitter agent
definition: Any agent that acts on an opioid receptor or affects the life cycle of an opioid transmitter.
id: CHEBI:60598
has_obo_namespace: chebi_ontology
has_related_synonym: opioid agents
in_subset: 3 STAR
imported from: chebi.owl

mu-opioid agent
type: Class
subclass of: opioid agent
definition: Any agent that acts on a mu-opioid receptor.
id: CHEBI:60599
has_obo_namespace: chebi_ontology
has_related_synonym: mu-opioid agents
in_subset: 3 STAR
imported from: chebi.owl

delta-opioid agent
type: Class
subclass of: opioid agent
definition: Any agent that acts on a delta-opioid receptor.
id: CHEBI:60601
has_obo_namespace: chebi_ontology
has_related_synonym: delta-opioid agents
in_subset: 3 STAR
imported from: chebi.owl

kappa-opioid agent
type: Class
subclass of: opioid agent
definition: Any agent that acts on a kappa-opioid receptor.
id: CHEBI:60603
has_obo_namespace: chebi_ontology
has_related_synonym: kappa-opioid agents
in_subset: 3 STAR
imported from: chebi.owl

opioid receptor antagonist
type: Class
subclass of: antagonist
subclass of: opioid agent
definition: An agent that binds to but does not activate an opioid receptor thereby blocking the actions of endogenous or exogenous opioid receptor agonists.
id: CHEBI:60605
database_cross_reference: Wikipedia:Opioid_antagonist
has_obo_namespace: chebi_ontology
has_related_synonym: opiate antagonist
has_related_synonym: opiate antagonists
has_related_synonym: opioid antagonist
has_related_synonym: opioid antagonists
has_related_synonym: opioid receptor antagonists
in_subset: 3 STAR
imported from: chebi.owl

opioid receptor agonist
type: Class
subclass of: agonist
subclass of: opioid agent
definition: An agent that selectively binds to and activates an opioid receptor.
id: CHEBI:60606
has_obo_namespace: chebi_ontology
has_related_synonym: opiate agonist
has_related_synonym: opiate agonists
has_related_synonym: opioid agonist
has_related_synonym: opioid agonists
has_related_synonym: opioid receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

NMDA receptor antagonist
type: Class
subclass of: excitatory amino acid antagonist
definition: Any substance that inhibits the action of N-methyl-D-aspartate (NMDA) receptors. They tend to induce a state known as dissociative anesthesia, marked by catalepsy, amnesia, and analgesia, while side effects can include hallucinations, nightmares, and confusion. Due to their psychotomimetic effects, many NMDA receptor antagonists are used as recreational drugs.
id: CHEBI:60643
has_alternative_id: CHEBI:60797
has_related_synonym: N-methyl-D-aspartate receptor antagonist
has_related_synonym: N-methyl-D-aspartate receptor antagonists
has_related_synonym: NMDA receptor antagonists
has_related_synonym: NMDAR antagonist
has_related_synonym: NMDAR antagonists
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

chiral reagent
type: Class
subclass of: reagent
definition: A chiral compound used to induce stereoselectivity into a reaction.
id: CHEBI:60646
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

glucagon receptor antagonist
type: Class
subclass of: hormone antagonist
definition: An agent which blocks glucagon receptors.
id: CHEBI:60649
has_obo_namespace: chebi_ontology
has_related_synonym: glucagon receptor antagonists
in_subset: 3 STAR
imported from: chebi.owl

EC 4.2.1.20 (tryptophan synthase) inhibitor
type: Class
subclass of: EC 4.2.1.* (hydro-lyases) inhibitor
definition: An EC 4.2.1.* (hydro-lyases) inhibitor that interferes with the action of tryptophan synthase (EC 4.2.1.20).
id: CHEBI:60688
has_related_synonym: EC 4.2.1.20 (tryptophan synthase) inhibitors
has_related_synonym: EC 4.2.1.20 inhibitor
has_related_synonym: EC 4.2.1.20 inhibitors
has_related_synonym: L-serine hydro-lyase (adding indoleglycerol-phosphate) inhibitor
has_related_synonym: L-serine hydro-lyase (adding indoleglycerol-phosphate) inhibitors
has_related_synonym: L-tryptophan synthetase inhibitor
has_related_synonym: L-tryptophan synthetase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: indoleglycerol phosphate aldolase inhibitor
has_related_synonym: indoleglycerol phosphate aldolase inhibitors
has_related_synonym: tryptophan desmolase inhibitor
has_related_synonym: tryptophan desmolase inhibitors
has_related_synonym: tryptophan synthase (EC 4.2.1.20) inhibitor
has_related_synonym: tryptophan synthase (EC 4.2.1.20) inhibitors
has_related_synonym: tryptophan synthase inhibitor
has_related_synonym: tryptophan synthase inhibitors
has_related_synonym: tryptophan synthetase inhibitor
has_related_synonym: tryptophan synthetase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

affinity label
type: Class
subclass of: enzyme inhibitor
definition: An enzyme inhibitor, generally irreversible, that is similar in structure to a particular substrate for a specific enzyme.
id: CHEBI:60788
database_cross_reference: Wikipedia:Affinity_label
has_related_synonym: affinity labels
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

excitatory amino acid antagonist
type: Class
subclass of: antagonist
definition: Any substance which inhibits the action of receptors for excitatory amino acids.
id: CHEBI:60798
has_related_synonym: EAA receptor antagonist
has_related_synonym: EAA receptor antagonists
has_obo_namespace: chebi_ontology
has_related_synonym: excitatory amino acid antagonists
has_related_synonym: excitatory amino acid receptor antagonist
has_related_synonym: excitatory amino acid receptor antagonists
in_subset: 3 STAR
imported from: chebi.owl

anaesthesia adjuvant
type: Class
subclass of: adjuvant
definition: Any substance that possesses little anaesthetic effect by itself, but which enhances or potentiates the anaesthetic action of other drugs when given at the same time.
id: CHEBI:60807
has_related_synonym: anaesthesia adjuvants
has_related_synonym: anaesthestic adjuvant
has_related_synonym: anaesthestic adjuvants
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

adjuvant
type: Class
subclass of: pharmaceutical
definition: Any pharmacological or immunological agent that modifies the effect of other agents such as drugs or vaccines while having few if any direct effects when given by itself.
id: CHEBI:60809
has_related_synonym: adjuvants
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

immunogen
type: Class
subclass of: antigen
definition: An antigen capable, on its own, of inducing an immune response.
id: CHEBI:60816
database_cross_reference: PMID:19152635
database_cross_reference: PMID:19328011
database_cross_reference: PMID:19397283
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

tubulin modulator
type: Class
subclass of: pharmacological role
definition: Any substance that interacts with tubulin to inhibit or promote polymerisation of microtubules.
id: CHEBI:60832
has_obo_namespace: chebi_ontology
has_related_synonym: tubulin modulators
in_subset: 3 STAR
imported from: chebi.owl

EC 2.5.1.9 (riboflavin synthase) inhibitor
type: Class
subclass of: EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor
has_related_synonym: 6,7-dimethyl-8-(1-D-ribityl)lumazine:6,7-dimethyl-8-(1-D-ribityl)lumazine 2,3-butanediyltransferase inhibitor
has_related_synonym: 6,7-dimethyl-8-(1-D-ribityl)lumazine:6,7-dimethyl-8-(1-D-ribityl)lumazine 2,3-butanediyltransferase inhibitors
definition: An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that inhibits the action of riboflavin synthase (EC 2.5.1.9).
id: CHEBI:60901
has_related_synonym: EC 2.5.1.9 (riboflavin synthase) inhibitors
has_related_synonym: EC 2.5.1.9 inhibitor
has_related_synonym: EC 2.5.1.9 inhibitors
database_cross_reference: Wikipedia:Riboflavin_synthase
has_obo_namespace: chebi_ontology
has_related_synonym: heavy riboflavin synthase inhibitor
has_related_synonym: heavy riboflavin synthase inhibitors
has_related_synonym: light riboflavin synthase inhibitor
has_related_synonym: light riboflavin synthase inhibitors
has_related_synonym: riboflavin synthase (EC 2.5.1.9) inhibitor
has_related_synonym: riboflavin synthase (EC 2.5.1.9) inhibitors
has_related_synonym: riboflavin synthase inhibitor
has_related_synonym: riboflavin synthase inhibitors
has_related_synonym: riboflavin synthetase inhibitor
has_related_synonym: riboflavin synthetase inhibitors
has_related_synonym: riboflavine synthase inhibitor
has_related_synonym: riboflavine synthase inhibitors
has_related_synonym: riboflavine synthetase inhibitor
has_related_synonym: riboflavine synthetase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

nephrotoxin
type: Class
subclass of: toxin
subclass of: nephrotoxic agent
definition: A toxin that is produced by a biological organism such as a microbe, animal or plant which interferes with the function of the kidney in animals.
id: CHEBI:61015
has_obo_namespace: chebi_ontology
has_related_synonym: nephrotoxins
in_subset: 3 STAR
imported from: chebi.owl

angiotensin receptor antagonist
type: Class
subclass of: hormone antagonist
definition: A hormone antagonist that blocks angiotensin receptors.
id: CHEBI:61016
has_related_synonym: angiotensin receptor antagonists
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

bile therapy drug
type: Class
subclass of: drug
definition: A drug used in the treatment of bile or liver disorders.
id: CHEBI:61026
has_related_synonym: bile therapy agent
has_related_synonym: bile therapy agents
has_related_synonym: bile therapy drugs
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 3.5.1.98 (histone deacetylase) inhibitor
type: Class
subclass of: EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor
definition: An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the function of histone deacetylase (EC 3.5.1.98).
id: CHEBI:61115
has_related_synonym: EC 3.5.1.98 (histone deacetylase) inhibitors
has_related_synonym: EC 3.5.1.98 inhibitor
has_related_synonym: EC 3.5.1.98 inhibitors
has_related_synonym: HDAC inhibitor
has_related_synonym: HDAC inhibitors
has_related_synonym: HDACi
has_related_synonym: HDACis
has_related_synonym: HDI
has_related_synonym: HDIs
database_cross_reference: Wikipedia:Histone_deacetylase_inhibitor
has_obo_namespace: chebi_ontology
has_related_synonym: histone amidohydrolase inhibitor
has_related_synonym: histone amidohydrolase inhibitors
has_related_synonym: histone deacetylase (EC 3.5.1.98) inhibitor
has_related_synonym: histone deacetylase (EC 3.5.1.98) inhibitors
has_related_synonym: histone deacetylase inhibitor
has_related_synonym: histone deacetylase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

inositol phosphorylceramide synthase inhibitor
type: Class
subclass of: EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor
definition: An enzyme inhibitor that inhibits the action of inositol phosphorylceramide synthase.
id: CHEBI:61774
database_cross_reference: PMID:17420564
database_cross_reference: PMID:17420565
database_cross_reference: PMID:19644518
database_cross_reference: PMID:19644519
database_cross_reference: PMID:19662087
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 1.14.13.39 (nitric oxide synthase) inhibitor
type: Class
subclass of: EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor
definition: An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of nitric oxide synthase (EC 1.14.13.39).
id: CHEBI:61908
has_related_synonym: EC 1.14.13.39 (nitric oxide synthase) inhibitors
has_related_synonym: EC 1.14.13.39 inhibitor
has_related_synonym: EC 1.14.13.39 inhibitors
has_related_synonym: NADPH-diaphorase inhibitor
has_related_synonym: NADPH-diaphorase inhibitors
has_related_synonym: NO synthase inhibitor
has_related_synonym: NO synthase inhibitors
database_cross_reference: Wikipedia:Nitric_oxide_synthase
has_obo_namespace: chebi_ontology
has_related_synonym: endothelium-derived relaxation factor-forming enzyme inhibitor
has_related_synonym: endothelium-derived relaxation factor-forming enzyme inhibitors
has_related_synonym: endothelium-derived relaxing factor synthase inhibitor
has_related_synonym: endothelium-derived relaxing factor synthase inhibitors
has_related_synonym: nitric oxide synthase (EC 1.14.13.39) inhibitor
has_related_synonym: nitric oxide synthase (EC 1.14.13.39) inhibitors
has_related_synonym: nitric oxide synthase inhibitor
has_related_synonym: nitric oxide synthase inhibitors
has_related_synonym: nitric oxide synthetase inhibitor
has_related_synonym: nitric oxide synthetase inhibitors
has_related_synonym: nitric-oxide synthetase inhibitor
has_related_synonym: nitric-oxide synthetase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

microtubule-stabilising agent
type: Class
subclass of: tubulin modulator
definition: Any substance that interacts with tubulin to promote polymerisation of microtubules.
id: CHEBI:61950
database_cross_reference: PMID:11470606
has_obo_namespace: chebi_ontology
has_related_synonym: microtubule stabilising agent
has_related_synonym: microtubule stabilising role
has_related_synonym: microtubule stabilizing agent
has_related_synonym: microtubule stabilizing agents
has_related_synonym: microtubule stabilizing role
has_related_synonym: microtubule-stabilising agents
has_related_synonym: microtubule-stabilizing agent
in_subset: 3 STAR
imported from: chebi.owl

microtubule-destabilising agent
type: Class
subclass of: tubulin modulator
subclass of: antimitotic
definition: Any substance that interacts with tubulin to inhibit polymerisation of microtubules.
id: CHEBI:61951
database_cross_reference: PMID:17099073
has_obo_namespace: chebi_ontology
has_related_synonym: microtubule destabilising agent
has_related_synonym: microtubule destabilising agents
has_related_synonym: microtubule destabilising role
has_related_synonym: microtubule destabilizing role
has_related_synonym: microtubule-destabilising agents
has_related_synonym: microtubule-destabilizing agent
has_related_synonym: microtubule-destabilizing agents
in_subset: 3 STAR
imported from: chebi.owl

metabotropic glutamate receptor agonist
type: Class
subclass of: agonist
definition: An agonist that selectively binds to and activates a metabotropic glutamate receptor.
id: CHEBI:61966
has_obo_namespace: chebi_ontology
has_related_synonym: mGluRs agonist
has_related_synonym: metabotropic glutamate receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

acyl donor
type: Class
subclass of: donor
definition: Any donor that can transfer acyl groups between molecular entities.
id: CHEBI:62049
database_cross_reference: PMID:16100120
database_cross_reference: PMID:19052863
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 1.4.7.1 [glutamate synthase (ferredoxin)] inhibitor
type: Class
subclass of: EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor
definition: An EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor that interferes with the action of any glutamate synthase.
id: CHEBI:62089
has_related_synonym: EC 1.4.7.1 [glutamate synthase (ferredoxin)] inhibitors
has_related_synonym: EC 1.4.7.1 inhibitor
has_related_synonym: EC 1.4.7.1 inhibitors
has_related_synonym: L-glutamate:ferredoxin oxidoreductase (transaminating) inhibitor
has_related_synonym: L-glutamate:ferredoxin oxidoreductase (transaminating) inhibitors
database_cross_reference: Wikipedia:Glutamate_synthase_(ferredoxin)
has_obo_namespace: chebi_ontology
has_related_synonym: ferredoxin-dependent glutamate synthase inhibitor
has_related_synonym: ferredoxin-dependent glutamate synthase inhibitors
has_related_synonym: ferredoxin-glutamate synthase inhibitor
has_related_synonym: ferredoxin-glutamate synthase inhibitors
has_related_synonym: glutamate synthase (ferredoxin) (EC 1.4.7.1) inhibitor
has_related_synonym: glutamate synthase (ferredoxin) (EC 1.4.7.1) inhibitors
has_related_synonym: glutamate synthase (ferredoxin) inhibitor
has_related_synonym: glutamate synthase (ferredoxin) inhibitors
has_related_synonym: glutamate synthase (ferredoxin-dependent) inhibitor
has_related_synonym: glutamate synthase (ferredoxin-dependent) inhibitors
has_related_synonym: glutamate synthase inhibitor
has_related_synonym: glutamate synthase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

allelochemical
type: Class
subclass of: metabolite
definition: A class of secondary metabolites developed by many plants to influence the behaviour, growth or survival of herbivores, and thus acting as a defence against herbivory.
id: CHEBI:62215
has_related_synonym: allelochemicals
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
type: Class
subclass of: tyrosine kinase inhibitor
subclass of: EC 2.7.10.* (protein-tyrosine kinase) inhibitor
has_related_synonym: AATK inhibitor
has_related_synonym: AATYK inhibitor
has_related_synonym: AATYK2 inhibitor
has_related_synonym: AATYK3 inhibitor
has_related_synonym: ACH inhibitor
has_related_synonym: ALK inhibitor
has_related_synonym: ALK inhibitors
has_related_synonym: ARK inhibitor
has_related_synonym: ATP:[protein]-L-tyrosine O-phosphotransferase (receptor-type) inhibitor
has_related_synonym: ATP:[protein]-L-tyrosine O-phosphotransferase (receptor-type) inhibitors
has_related_synonym: AXL inhibitor
definition: An EC 2.7.10.* (protein-tyrosine kinase) inhibitor that interferes with the action of receptor protein-tyrosine kinase (EC 2.7.10.1).
has_related_synonym: BRT inhibitor
has_related_synonym: Bek inhibitor
has_related_synonym: Bfgfr inhibitor
has_related_synonym: Bsk inhibitor
has_related_synonym: C-FMS inhibitor
has_related_synonym: CAK inhibitor
has_related_synonym: CCK4 inhibitor
has_related_synonym: CD115 inhibitor
has_related_synonym: CD135 inhibitor
has_related_synonym: CDw135 inhibitor
has_related_synonym: CFD1 inhibitor
id: CHEBI:62434
has_related_synonym: CKIT inhibitor
has_related_synonym: CSF1R inhibitor
has_related_synonym: Cek1 inhibitor
has_related_synonym: Cek10 inhibitor
has_related_synonym: Cek11 inhibitor
has_related_synonym: Cek2 inhibitor
has_related_synonym: Cek3 inhibitor
has_related_synonym: Cek5 inhibitor
has_related_synonym: Cek6 inhibitor
has_related_synonym: Cek7 inhibitor
has_related_synonym: DAlk inhibitor
has_related_synonym: DDR1 inhibitor
has_related_synonym: DDR2 inhibitor
has_related_synonym: DKFZp434C1418 inhibitor
has_related_synonym: DRT inhibitor
has_related_synonym: DTK inhibitor
has_related_synonym: Dek inhibitor
has_related_synonym: Drosophila Eph kinase inhibitor
has_related_synonym: EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitors
has_related_synonym: EC 2.7.10.1 inhibitor
has_related_synonym: EC 2.7.10.1 inhibitors
has_related_synonym: ECK inhibitor
has_related_synonym: EDDR1 inhibitor
has_related_synonym: EGFR inhibitor
has_related_synonym: EPH inhibitor
has_related_synonym: EPHA1 inhibitor
has_related_synonym: EPHA2 inhibitor
has_related_synonym: EPHA6 inhibitor
has_related_synonym: EPHA7 inhibitor
has_related_synonym: EPHA8 inhibitor
has_related_synonym: EPHB1 inhibitor
has_related_synonym: EPHB2 inhibitor
has_related_synonym: EPHB3 inhibitor
has_related_synonym: EPHB4 inhibitor
has_related_synonym: EPHT inhibitor
has_related_synonym: EPHT2 inhibitor
has_related_synonym: EPHT3 inhibitor
has_related_synonym: EPHX inhibitor
has_related_synonym: ERBB inhibitor
has_related_synonym: ERBB1 inhibitor
has_related_synonym: ERBB2 inhibitor
has_related_synonym: ERBB3 inhibitor
has_related_synonym: ERBB4 inhibitor
has_related_synonym: ERK inhibitor
has_related_synonym: Ebk inhibitor
has_related_synonym: Eek inhibitor
has_related_synonym: Ehk2 inhibitor
has_related_synonym: Ehk3 inhibitor
has_related_synonym: Elk inhibitor
has_related_synonym: EphB5 inhibitor
has_related_synonym: Eyk inhibitor
has_related_synonym: FGFR1 inhibitor

signalling molecule
type: Class
subclass of: molecular messenger
definition: A molecular messenger in which the molecule is specifically involved in transmitting information between cells. Such molecules are released from the cell sending the signal, cross over the gap between cells by diffusion, and interact with specific receptors in another cell, triggering a response in that cell by activating a series of enzyme controlled reactions which lead to changes inside the cell.
id: CHEBI:62488
has_obo_namespace: chebi_ontology
has_related_synonym: signal molecule
has_related_synonym: signal molecules
has_related_synonym: signaling molecule
has_related_synonym: signaling molecules
has_related_synonym: signalling molecules
in_subset: 3 STAR
imported from: chebi.owl

EC 2.3.1.24 (sphingosine N-acyltransferase) inhibitor
type: Class
subclass of: EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor
definition: An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of sphingosine N-acyltransferase (EC 2.3.1.24).
id: CHEBI:62530
has_related_synonym: EC 2.3.1.24 (sphingosine N-acyltransferase) inhibitors
has_related_synonym: EC 2.3.1.24 inhibitor
has_related_synonym: EC 2.3.1.24 inhibitors
database_cross_reference: Wikipedia:Sphingosine_N-acyltransferase
has_related_synonym: acyl-CoA:sphingosine N-acyltransferase inhibitor
has_related_synonym: acyl-CoA:sphingosine N-acyltransferase inhibitors
has_related_synonym: ceramide synthase inhibitor
has_related_synonym: ceramide synthase inhibitors
has_related_synonym: ceramide synthetase inhibitor
has_related_synonym: ceramide synthetase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: sphingosine N-acyltransferase (EC 2.3.1.24) inhibitor
has_related_synonym: sphingosine N-acyltransferase (EC 2.3.1.24) inhibitors
has_related_synonym: sphingosine N-acyltransferase inhibitor
has_related_synonym: sphingosine N-acyltransferase inhibitors
has_related_synonym: sphingosine acyltransferase inhibitor
has_related_synonym: sphingosine acyltransferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 4.2.1.3 (aconitate hydratase) inhibitor
type: Class
subclass of: EC 4.2.1.* (hydro-lyases) inhibitor
has_related_synonym: 2-methylaconitate hydratase inhibitor
has_related_synonym: 2-methylaconitate hydratase inhibitors
has_related_synonym: 4.2.1.3 inhibitor
has_related_synonym: 4.2.1.3 inhibitors
has_related_synonym: AcnB inhibitor
has_related_synonym: AcnB inhibitors
definition: An EC 4.2.1.* (hydro-lyases) inhibitor that interferes with the function of aconitase (EC 4.2.1.3).
id: CHEBI:62608
has_related_synonym: EC 4.2.1.3 (aconitate hydratase) inhibitors
has_related_synonym: aconitase inhibitor
has_related_synonym: aconitase inhibitors
has_related_synonym: aconitate hydratase (EC 4.2.1.3) inhibitor
has_related_synonym: aconitate hydratase (EC 4.2.1.3) inhibitors
has_related_synonym: aconitate hydratase inhibitor
has_related_synonym: aconitate hydratase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: cis-aconitase inhibitor
has_related_synonym: cis-aconitase inhibitors
has_related_synonym: citrate hydro-lyase inhibitor
has_related_synonym: citrate hydro-lyase inhibitors
has_related_synonym: citrate(isocitrate) hydro-lyase (cis-aconitate-forming) inhibitor
has_related_synonym: citrate(isocitrate) hydro-lyase (cis-aconitate-forming) inhibitors
has_related_synonym: citrate(isocitrate) hydro-lyase inhibitor
has_related_synonym: citrate(isocitrate) hydro-lyase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.11.1.3 (phosphonopyruvate hydrolase) inhibitor
type: Class
subclass of: EC 3.11.1.* (hydrolases acting on C-P bonds of phosphono-acetaldehyde, -acetate, or -pyruvate) inhibitor
definition: An EC 3.11.1.* (hydrolases acting on C-P bonds of phosphono-acetaldehyde, -acetate, or -pyruvate) inhibitor that interferes with the action of phosphonopyruvate hydrolase (EC 3.11.1.3).
id: CHEBI:62609
has_related_synonym: EC 3.11.1.3 (phosphonopyruvate hydrolase) inhibitors
has_related_synonym: EC 3.11.1.3 inhibitor
has_related_synonym: EC 3.11.1.3 inhibitors
has_related_synonym: PPH inhibitor
has_related_synonym: PPH inhibitors
database_cross_reference: Wikipedia:Phosphonopyruvate_hydrolase
has_obo_namespace: chebi_ontology
has_related_synonym: phosphonopyruvate hydrolase (EC 3.11.1.3) inhibitor
has_related_synonym: phosphonopyruvate hydrolase (EC 3.11.1.3) inhibitors
has_related_synonym: phosphonopyruvate hydrolase inhibitor
has_related_synonym: phosphonopyruvate hydrolase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

glycine receptor antagonist
type: Class
subclass of: antagonist
definition: An antagonist that blocks glycine receptors.
id: CHEBI:62754
has_obo_namespace: chebi_ontology
has_related_synonym: glycine receptor antagonists
in_subset: 3 STAR
imported from: chebi.owl

fuel additive
type: Class
subclass of: chemical role
definition: Any additive that enhances the efficiency of fuel.
id: CHEBI:62803
has_obo_namespace: chebi_ontology
has_related_synonym: fuel additives
has_related_synonym: fuel enhancer
in_subset: 3 STAR
imported from: chebi.owl

hepatoprotective agent
type: Class
subclass of: protective agent
definition: Any compound that is able to prevent damage to the liver.
id: CHEBI:62868
has_related_synonym: antihepatotoxic agent
has_obo_namespace: chebi_ontology
has_related_synonym: hepatoprotective agents
has_related_synonym: hepatoprotector
in_subset: 3 STAR
imported from: chebi.owl

EC 4.3.1.24 (phenylalanine ammonia-lyase) inhibitor
type: Class
subclass of: EC 4.3.1.* (ammonia-lyase) inhibitor
definition: An EC 4.3.* (C-N lyase) inhibitor that interferes with the action of phenylalanine ammonia-lyase (EC 4.3.1.24).
id: CHEBI:62871
has_related_synonym: EC 4.3.1.24 (phenylalanine ammonia-lyase) inhibitors
has_related_synonym: EC 4.3.1.24 inhibitor
has_related_synonym: EC 4.3.1.24 inhibitors
has_related_synonym: L-phenylalanine ammonia-lyase (trans-cinnamate-forming) inhibitor
has_related_synonym: L-phenylalanine ammonia-lyase (trans-cinnamate-forming) inhibitors
has_related_synonym: L-phenylalanine ammonia-lyase inhibitor
has_related_synonym: L-phenylalanine ammonia-lyase inhibitors
has_related_synonym: PAL inhibitor
has_related_synonym: PAL inhibitors
has_related_synonym: Phe ammonia-lyase inhibitor
has_related_synonym: Phe ammonia-lyase inhibitors
database_cross_reference: Wikipedia:Phenylalanine_ammonia-lyase
has_obo_namespace: chebi_ontology
has_related_synonym: phenylalanine ammonia-lyase (EC 4.3.1.24) inhibitor
has_related_synonym: phenylalanine ammonia-lyase (EC 4.3.1.24) inhibitors
has_related_synonym: phenylalanine ammonia-lyase inhibitor
has_related_synonym: phenylalanine ammonia-lyase inhibitors
has_related_synonym: phenylalanine ammonium-lyase inhibitor
has_related_synonym: phenylalanine ammonium-lyase inhibitors
has_related_synonym: phenylalanine deaminase inhibitor
has_related_synonym: phenylalanine deaminase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.2.3.1 (aldehyde oxidase) inhibitor
type: Class
subclass of: EC 1.2.3.* (oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor) inhibitor
definition: An EC 1.2.3.* (oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor) inhibitor which interferes with the action of aldehyde oxidase (EC 1.2.3.1).
id: CHEBI:62872
has_related_synonym: EC 1.2.3.1 (aldehyde oxidase) inhibitors
has_related_synonym: EC 1.2.3.1 inhibitor
has_related_synonym: EC 1.2.3.1 inhibitors
database_cross_reference: Wikipedia:Aldehyde_oxidase
has_related_synonym: aldehyde oxidase (EC 1.2.3.1) inhibitor
has_related_synonym: aldehyde oxidase (EC 1.2.3.1) inhibitors
has_related_synonym: aldehyde oxidase inhibitor
has_related_synonym: aldehyde oxidase inhibitors
has_related_synonym: aldehyde:oxygen oxidoreductase inhibitor
has_related_synonym: aldehyde:oxygen oxidoreductase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: quinoline oxidase inhibitor
has_related_synonym: quinoline oxidase inhibitors
has_related_synonym: retinal oxidase inhibitor
has_related_synonym: retinal oxidase inhibitors
has_related_synonym: retinoic acid synthase inhibitor
has_related_synonym: retinoic acid synthase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

odorant receptor agonist
type: Class
subclass of: agonist
definition: An agonist that selectively binds to and activates an odorant receptor.
id: CHEBI:62873
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

tankyrase inhibitor
type: Class
subclass of: EC 2.4.* (glycosyltransferase) inhibitor
definition: Any compound that inhibits the action of tankyrase.
id: CHEBI:62887
has_obo_namespace: chebi_ontology
has_related_synonym: tankyrase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor
type: Class
subclass of: EC 2.4.2.* (pentosyltransferase) inhibitor
has_related_synonym: ADP-ribosyltransferase (polymerising) inhibitor
has_related_synonym: ADP-ribosyltransferase (polymerising) inhibitors
has_related_synonym: ADP-ribosyltransferase (polymerizing) inhibitor
has_related_synonym: ADP-ribosyltransferase (polymerizing) inhibitors
definition: An EC 2.4.2.* (pentosyltransferase) inhibitor that interferes with the action of a NAD(+) ADP-ribosyltransferase (EC 2.4.2.30).
id: CHEBI:62913
has_related_synonym: EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitors
has_related_synonym: EC 2.4.2.30 inhibitor
has_related_synonym: EC 2.4.2.30 inhibitors
has_related_synonym: NAD(+) ADP-ribosyltransferase (EC 2.4.2.30) inhibitor
has_related_synonym: NAD(+) ADP-ribosyltransferase (EC 2.4.2.30) inhibitors
has_related_synonym: NAD(+) ADP-ribosyltransferase inhibitor
has_related_synonym: NAD(+) ADP-ribosyltransferase inhibitors
has_related_synonym: NAD(+):poly(ADP-D-ribosyl)-acceptor ADP-D-ribosyl-transferase inhibitor
has_related_synonym: NAD(+):poly(ADP-D-ribosyl)-acceptor ADP-D-ribosyl-transferase inhibitors
has_related_synonym: NAD(+):poly(adenosine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase inhibitor
has_related_synonym: NAD(+):poly(adenosine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase inhibitors
has_related_synonym: PARP
has_related_synonym: PARPs
database_cross_reference: Wikipedia:PARP_inhibitor
has_obo_namespace: chebi_ontology
has_related_synonym: poly(ADP-ribose) polymerase inhibitor
has_related_synonym: poly(ADP-ribose) polymerase inhibitors
has_related_synonym: poly(ADP-ribose) synthase inhibitor
has_related_synonym: poly(ADP-ribose) synthase inhibitors
has_related_synonym: poly(ADP-ribose) synthetase inhibitor
has_related_synonym: poly(ADP-ribose) synthetase inhibitors
has_related_synonym: poly(adenosine diphosphate ribose) polymerase inhibitor
has_related_synonym: poly(adenosine diphosphate ribose) polymerase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

axin stabilizer
type: Class
subclass of: biochemical role
id: CHEBI:62914
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

sialyltransferase inhibitor
type: Class
subclass of: EC 2.4.99.* (glycosyltransferases transferring other glycosyl groups) inhibitor
definition: An EC 2.4.99.* (glycosyltransferases transferring other glycosyl groups) inhibitor that interferes with the action of a sialyltransferase.
id: CHEBI:62915
has_obo_namespace: chebi_ontology
has_related_synonym: sialyltransferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

emulsifier
type: Class
subclass of: chemical role
id: CHEBI:63046
definition: The chemical role played by a substance that stabilizes an emulsion by increasing its kinetic stability.
has_obo_namespace: chebi_ontology
has_related_synonym: emulgent
has_related_synonym: emulgents
has_related_synonym: emulsifiers
in_subset: 3 STAR
imported from: chebi.owl

food emulsifier
type: Class
subclass of: emulsifier
subclass of: food additive
definition: A food additive used to form or maintain a uniform emulsion of two (or more) phases in a food.
id: CHEBI:63047
has_obo_namespace: chebi_ontology
has_related_synonym: food emulsifiers
in_subset: 3 STAR
imported from: chebi.owl

osteogenesis regulator
type: Class
subclass of: growth regulator
definition: Any compound that induces or regulates osteogenesis.
id: CHEBI:63054
has_obo_namespace: chebi_ontology
has_related_synonym: osteogenesis regulators
in_subset: 3 STAR
imported from: chebi.owl

phase-transfer catalyst
type: Class
subclass of: catalyst
definition: A catalyst that facilitates the migration of a reactant from one phase into another phase where reaction occurs.
id: CHEBI:63060
has_related_synonym: PTC
database_cross_reference: Wikipedia:Phase_transfer_catalyst
has_obo_namespace: chebi_ontology
has_related_synonym: phase transfer catalyst
has_related_synonym: phase transfer catalysts
has_related_synonym: phase-transfer catalysts
in_subset: 3 STAR
imported from: chebi.owl

crystallisation adjutant
type: Class
subclass of: chemical role
id: CHEBI:63064
definition: Chemical role played by a material when used to promote crystallisation.
database_cross_reference: Wikipedia:Crystallization_adjutant
has_obo_namespace: chebi_ontology
has_related_synonym: crystallisation adjutants
has_related_synonym: crystallization adjutant
has_related_synonym: crystallization adjutants
in_subset: 3 STAR
imported from: chebi.owl

EC 2.4.2.1 (purine-nucleoside phosphorylase) inhibitor
type: Class
subclass of: EC 2.4.2.* (pentosyltransferase) inhibitor
definition: An EC 2.4.2.* (pentosyltransferase) inhibitor that interferes with the action of purine nucleoside phosphorylase (EC 2.4.2.1).
id: CHEBI:63090
has_related_synonym: EC 2.4.2.1 (purine-nucleoside phosphorylase) inhibitors
has_related_synonym: EC 2.4.2.1 inhibitor
has_related_synonym: EC 2.4.2.1 inhibitors
has_related_synonym: PNPase inhibitor
has_related_synonym: PNPase inhibitors
has_related_synonym: PUNPI inhibitor
has_related_synonym: PUNPI inhibitors
has_related_synonym: PUNPII inhibitor
has_related_synonym: PUNPII inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inosine phosphorylase inhibitor
has_related_synonym: inosine phosphorylase inhibitors
has_related_synonym: inosine-guanosine phosphorylase inhibitor
has_related_synonym: inosine-guanosine phosphorylase inhibitors
has_related_synonym: nucleotide phosphatase inhibitor
has_related_synonym: nucleotide phosphatase inhibitors
has_related_synonym: purine deoxynucleoside phosphorylase inhibitor
has_related_synonym: purine deoxynucleoside phosphorylase inhibitors
has_related_synonym: purine deoxyribonucleoside phosphorylase inhibitor
has_related_synonym: purine deoxyribonucleoside phosphorylase inhibitors
has_related_synonym: purine nucleoside phosphorylase inhibitor
has_related_synonym: purine nucleoside phosphorylase inhibitors
has_related_synonym: purine ribonucleoside phosphorylase inhibitor
has_related_synonym: purine ribonucleoside phosphorylase inhibitors
has_related_synonym: purine-nucleoside phosphorylase (EC 2.4.2.1) inhibitor
has_related_synonym: purine-nucleoside phosphorylase (EC 2.4.2.1) inhibitors
has_related_synonym: purine-nucleoside phosphorylase inhibitor
has_related_synonym: purine-nucleoside phosphorylase inhibitors
has_related_synonym: purine-nucleoside:phosphate ribosyltransferase inhibitor
has_related_synonym: purine-nucleoside:phosphate ribosyltransferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

sphingosine-1-phosphate receptor agonist
type: Class
subclass of: agonist
definition: An agonist that binds to and activates sphingosine 1-phosphate receptors.
id: CHEBI:63114
has_alternative_id: CHEBI:63172
has_related_synonym: EDG receptor agonist
has_related_synonym: S1P receptor agonist
has_related_synonym: S1P receptor agonists
has_related_synonym: SIP agonist
has_related_synonym: SIP agonists
has_obo_namespace: chebi_ontology
has_related_synonym: sphingosine 1-phosphate receptor agonist
has_related_synonym: sphingosine 1-phosphate receptor agonists
has_related_synonym: sphingosine-1-phosphate receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

insulin release inhibitor
type: Class
subclass of: inhibitor
definition: Any substance that inhibits the release of insulin
id: CHEBI:63146
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 1.1.3.13 (alcohol oxidase) inhibitor
type: Class
subclass of: EC 1.1.3.* (oxidoreductase acting on donor CH-OH group, oxygen as acceptor) inhibitor
definition: An EC 1.1.3.* (oxidoreductase acting on donor CH-OH group, oxygen as acceptor) inhibitor that interferes with the action of alcohol oxidase (EC 1.1.3.13).
id: CHEBI:63156
has_related_synonym: EC 1.1.3.13 (alcohol oxidase) inhibitors
has_related_synonym: EC 1.1.3.13 inhibitor
has_related_synonym: EC 1.1.3.13 inhibitors
has_related_synonym: alcohol oxidase (EC 1.1.3.13) inhibitor
has_related_synonym: alcohol oxidase (EC 1.1.3.13) inhibitors
has_related_synonym: alcohol oxidase inhibitor
has_related_synonym: alcohol oxidase inhibitors
has_related_synonym: alcohol:oxygen oxidoreductase inhibitor
has_related_synonym: alcohol:oxygen oxidoreductase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: ethanol oxidase inhibitor
has_related_synonym: ethanol oxidase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 4.2.1.22 (cystathionine beta-synthase) inhibitor
type: Class
subclass of: EC 4.2.1.* (hydro-lyases) inhibitor
definition: An EC 4.2.1.* (hydro-lyases) inhibitor that interferes with the action of cystathionine beta-synthase (EC 4.2.1.22).
id: CHEBI:63157
has_related_synonym: EC 4.2.1.22 (cystathionine beta-synthase) inhibitors
has_related_synonym: EC 4.2.1.22 inhibitor
has_related_synonym: EC 4.2.1.22 inhibitors
has_related_synonym: L-serine hydro-lyase (adding homocysteine) inhibitor
has_related_synonym: L-serine hydro-lyase (adding homocysteine) inhibitors
has_related_synonym: L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming) inhibitor
has_related_synonym: L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming) inhibitors
has_related_synonym: beta-thionase inhibitor
has_related_synonym: beta-thionase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: cystathionine beta-synthase (EC 4.2.1.22) inhibitor
has_related_synonym: cystathionine beta-synthase (EC 4.2.1.22) inhibitors
has_related_synonym: cystathionine beta-synthase inhibitor
has_related_synonym: cystathionine beta-synthase inhibitors
has_related_synonym: cystathionine-beta-synthase inhibitor
has_related_synonym: cystathionine-beta-synthase inhibitors
has_related_synonym: cysteine synthase inhibitor
has_related_synonym: cysteine synthase inhibitors
has_related_synonym: methylcysteine synthase inhibitor
has_related_synonym: methylcysteine synthase inhibitors
has_related_synonym: serine sulfhydrase inhibitor
has_related_synonym: serine sulfhydrase inhibitors
has_related_synonym: serine sulfhydrylase inhibitor
has_related_synonym: serine sulfhydrylase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.3.1.21 (carnitine O-palmitoyltransferase) inhibitor
type: Class
subclass of: EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor
definition: An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of mitochondrial carnitine O-palmitoyltransferase (EC 2.3.1.21).
id: CHEBI:63158
has_related_synonym: CPT I (outer membrane carnitine palmitoyl transferase) inhibitor
has_related_synonym: CPT I (outer membrane carnitine palmitoyl transferase) inhibitors
has_related_synonym: CPT inhibitor
has_related_synonym: CPT inhibitors
has_related_synonym: CPT-A inhibitor
has_related_synonym: CPT-A inhibitors
has_related_synonym: CPT-B inhibitor
has_related_synonym: CPT-B inhibitors
has_related_synonym: CPTi inhibitor
has_related_synonym: CPTi inhibitors
has_related_synonym: CPTo inhibitor
has_related_synonym: CPTo inhibitors
has_related_synonym: CTP-1 inhibitor
has_related_synonym: CTP-1 inhibitors
has_related_synonym: EC 2.3.1.21 (carnitine O-palmitoyltransferase) inhibitors
has_related_synonym: EC 2.3.1.21 inhibitor
has_related_synonym: EC 2.3.1.21 inhibitors
has_related_synonym: L-carnitine palmitoyltransferase inhibitor
has_related_synonym: L-carnitine palmitoyltransferase inhibitors
has_related_synonym: acylcarnitine transferase inhibitor
has_related_synonym: acylcarnitine transferase inhibitors
has_related_synonym: carnitine O-palmitoyltransferase (EC 2.3.1.21) inhibitor
has_related_synonym: carnitine O-palmitoyltransferase (EC 2.3.1.21) inhibitors
has_related_synonym: carnitine O-palmitoyltransferase inhibitor
has_related_synonym: carnitine O-palmitoyltransferase inhibitors
has_related_synonym: carnitine palmitoyltransferase II inhibitor
has_related_synonym: carnitine palmitoyltransferase II inhibitors
has_related_synonym: carnitine palmitoyltransferase inhibitor
has_related_synonym: carnitine palmitoyltransferase inhibitors
has_related_synonym: carnitine palmitoyltransferase-1 inhibitor
has_related_synonym: carnitine palmitoyltransferase-1 inhibitors
has_related_synonym: carnitine palmitoyltransferase-A inhibitor
has_related_synonym: carnitine palmitoyltransferase-A inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: mitochondrial carnitine palmitoyltransferase-1 inhibitor
has_related_synonym: mitochondrial carnitine palmitoyltransferase-1 inhibitors
has_related_synonym: outer malonyl-CoA inhibitable carnitine palmitoyltransferase inhibitor
has_related_synonym: outer malonyl-CoA inhibitable carnitine palmitoyltransferase inhibitors
has_related_synonym: palmitoyl-CoA:L-carnitine O-palmitoyltransferase inhibitor
has_related_synonym: palmitoyl-CoA:L-carnitine O-palmitoyltransferase inhibitors
has_related_synonym: palmitoylcarnitine transferase inhibitor
has_related_synonym: palmitoylcarnitine transferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

T-cell proliferation inhibitor
type: Class
subclass of: inhibitor
definition: An inhibitor that interferes with the process of T-cell proliferation.
id: CHEBI:63173
has_related_synonym: T-cell proliferation inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

peptidomimetic
type: Class
subclass of: biochemical role
definition: A small protein-like chain designed to mimic a peptide.
id: CHEBI:63175
database_cross_reference: Wikipedia:Peptidomimetic
has_obo_namespace: chebi_ontology
has_related_synonym: peptidomimetics
in_subset: 3 STAR
imported from: chebi.owl

reducing agent
type: Class
subclass of: chemical role
id: CHEBI:63247
definition: The element or compound in a reduction-oxidation (redox) reaction that donates an electron to another species.
database_cross_reference: Wikipedia:Reducing_agent
has_obo_namespace: chebi_ontology
has_related_synonym: reducer
has_related_synonym: reducers
has_related_synonym: reducing agents
has_related_synonym: reductant
has_related_synonym: reductants
in_subset: 3 STAR
imported from: chebi.owl

oxidising agent
type: Class
subclass of: chemical role
definition: A substance that removes electrons from another reactant in a redox reaction.
id: CHEBI:63248
has_obo_namespace: chebi_ontology
has_related_synonym: oxidant
has_related_synonym: oxidants
has_related_synonym: oxidiser
has_related_synonym: oxidisers
has_related_synonym: oxidising agents
has_related_synonym: oxidizer
has_related_synonym: oxidizers
has_related_synonym: oxidizing agent
has_related_synonym: oxidizing agents
in_subset: 3 STAR
imported from: chebi.owl

sodium-dependent Pi-transporter inhibitor
type: Class
subclass of: inhibitor
definition: Any substance that inhibits the action of sodium-dependent Pi-transporters.
id: CHEBI:63330
has_related_synonym: NPC inhibitor
has_related_synonym: Na-Pi inhibitor
has_obo_namespace: chebi_ontology
has_related_synonym: sodium-dependent inorganic phosphate cotransporter inhibitor
has_related_synonym: sodium-dependent inorganic phosphate transporter inhibitor
in_subset: 3 STAR
imported from: chebi.owl

EC 3.1.3.1 (alkaline phosphatase) inhibitor
type: Class
subclass of: EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor
definition: An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of alkaline phosphatase (EC 3.1.3.1).
id: CHEBI:63332
has_related_synonym: EC 3.1.3.1 (alkaline phosphatase) inhibitors
has_related_synonym: EC 3.1.3.1 inhibitor
has_related_synonym: EC 3.1.3.1 inhibitors
database_cross_reference: Wikipedia:Alkaline_phosphatase
has_related_synonym: alkaline phenyl phosphatase inhibitor
has_related_synonym: alkaline phenyl phosphatase inhibitors
has_related_synonym: alkaline phosphatase (EC 3.1.3.1) inhibitor
has_related_synonym: alkaline phosphatase (EC 3.1.3.1) inhibitors
has_related_synonym: alkaline phosphatase inhibitor
has_related_synonym: alkaline phosphatase inhibitors
has_related_synonym: alkaline phosphohydrolase inhibitor
has_related_synonym: alkaline phosphohydrolase inhibitors
has_related_synonym: alkaline phosphomonoesterase inhibitor
has_related_synonym: alkaline phosphomonoesterase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: glycerophosphatase inhibitor
has_related_synonym: glycerophosphatase inhibitors
has_related_synonym: orthophosphoric-monoester phosphohydrolase (alkaline optimum) inhibitor
has_related_synonym: orthophosphoric-monoester phosphohydrolase (alkaline optimum) inhibitors
has_related_synonym: phosphate-monoester phosphohydrolase (alkaline optimum) inhibitor
has_related_synonym: phosphate-monoester phosphohydrolase (alkaline optimum) inhibitors
has_related_synonym: phosphomonoesterase inhibitor
has_related_synonym: phosphomonoesterase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

fibroblast growth factor receptor antagonist
type: Class
subclass of: antagonist
definition: An antagonist at the fibroblast growth factor receptor.
id: CHEBI:63457
has_related_synonym: FGFR inhibitor
has_related_synonym: FGFR inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: fibroblast growth factor receptor antagonists
has_related_synonym: fibroblast growth factor receptor inhibitor
has_related_synonym: fibroblast growth factor receptor inhibitors
in_subset: 3 STAR
imported from: chebi.owl

explosive
type: Class
subclass of: chemical role
definition: A substance capable of undergoing rapid and highly exothermic decomposition.
id: CHEBI:63490
database_cross_reference: Wikipedia:Explosive_material
has_obo_namespace: chebi_ontology
has_related_synonym: explosive compound
has_related_synonym: explosive compounds
has_related_synonym: explosive material
has_related_synonym: explosives
has_related_synonym: explosives chemical
has_related_synonym: explosives chemicals
in_subset: 3 STAR
imported from: chebi.owl

EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor
type: Class
subclass of: EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor
definition: An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of Na(+)/K(+)-transporting ATPase (EC 3.6.3.9).
id: CHEBI:63510
has_related_synonym: EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitors
has_related_synonym: EC 3.6.3.9 inhibitor
has_related_synonym: EC 3.6.3.9 inhibitors
has_related_synonym: Na(+)/K(+)-ATPase inhibitor
has_related_synonym: Na(+)/K(+)-ATPase inhibitors
has_related_synonym: Na(+)/K(+)-pump inhibitor
has_related_synonym: Na(+)/K(+)-pump inhibitors
has_related_synonym: Na(+)/K(+)-transporting ATPase (EC 3.6.3.9) inhibitor
has_related_synonym: Na(+)/K(+)-transporting ATPase (EC 3.6.3.9) inhibitors
has_related_synonym: Na(+)/K(+)-transporting ATPase inhibitor
has_related_synonym: Na(+)/K(+)-transporting ATPase inhibitors
database_cross_reference: Wikipedia:Sodium-potassium_ATPase
has_obo_namespace: chebi_ontology
has_related_synonym: sodium pump inhibitor
has_related_synonym: sodium pump inhibitors
has_related_synonym: sodium-potassium adenosine triphosphatase inhibitor
has_related_synonym: sodium-potassium adenosine triphosphatase inhibitors
has_related_synonym: sodium-potassium pump inhibitor
has_related_synonym: sodium-potassium pump inhibitors
in_subset: 3 STAR
imported from: chebi.owl

gonadotropin releasing hormone agonist
type: Class
subclass of: hormone agonist
definition: Any drug which binds to gonadotropin-releasing hormone receptors and triggers a response.
id: CHEBI:63533
has_related_synonym: GnRH agonist
has_related_synonym: GnRH agonists
has_related_synonym: GnRH-A
database_cross_reference: Wikipedia:Gonadotropin-releasing_hormone_agonist
has_obo_namespace: chebi_ontology
has_related_synonym: gonadotrophin releasing hormone agonist
has_related_synonym: gonadotrophin releasing hormone agonists
has_related_synonym: gonadotropin releasing hormone agonists
in_subset: 3 STAR
imported from: chebi.owl

glucocorticoid receptor agonist
type: Class
subclass of: agonist
definition: An agonist that selectively binds to and activates a glucocorticoid receptor.
id: CHEBI:63562
has_obo_namespace: chebi_ontology
has_related_synonym: glucocorticoid receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

chemokine receptor 5 antagonist
type: Class
subclass of: antagonist
definition: An antogonist that blocks chemokine receptor 5 (CCR5).
has_related_synonym: C-C chemokine receptor 5 antagonist
has_related_synonym: C-C chemokine receptor 5 antagonists
has_related_synonym: CCR-5 antagonist
has_related_synonym: CCR-5 antagonists
has_related_synonym: CCR5 antagonist
has_related_synonym: CCR5 antagonists
id: CHEBI:63673
database_cross_reference: Wikipedia:CCR5
has_obo_namespace: chebi_ontology
has_related_synonym: chemokine receptor 5 antagonists
in_subset: 3 STAR
imported from: chebi.owl

EC 2.6.1.19 (4-aminobutyrate--2-oxoglutarate transaminase) inhibitor
type: Class
subclass of: EC 2.6.1.* (transaminase) inhibitor
has_related_synonym: 4-aminobutanoate:2-oxoglutarate aminotransferase inhibitor
has_related_synonym: 4-aminobutanoate:2-oxoglutarate aminotransferase inhibitors
has_related_synonym: 4-aminobutyrate aminotransferase inhibitor
has_related_synonym: 4-aminobutyrate aminotransferase inhibitors
has_related_synonym: 4-aminobutyrate transaminase inhibitor
has_related_synonym: 4-aminobutyrate transaminase inhibitors
has_related_synonym: 4-aminobutyrate--2-ketoglutarate aminotransferase inhibitor
has_related_synonym: 4-aminobutyrate--2-ketoglutarate aminotransferase inhibitors
has_related_synonym: 4-aminobutyrate--2-oxoglutarate aminotransferase inhibitor
has_related_synonym: 4-aminobutyrate--2-oxoglutarate aminotransferase inhibitors
has_related_synonym: 4-aminobutyrate--2-oxoglutarate transaminase (EC 2.6.1.19) inhibitor
has_related_synonym: 4-aminobutyrate--2-oxoglutarate transaminase (EC 2.6.1.19) inhibitors
has_related_synonym: 4-aminobutyrate--2-oxoglutarate transaminase inhibitor
has_related_synonym: 4-aminobutyrate--2-oxoglutarate transaminase inhibitors
has_related_synonym: 4-aminobutyrate-2-oxoglutarate transaminase inhibitor
has_related_synonym: 4-aminobutyrate-2-oxoglutarate transaminase inhibitors
has_related_synonym: 4-aminobutyric acid 2-ketoglutaric acid aminotransferase inhibitor
has_related_synonym: 4-aminobutyric acid 2-ketoglutaric acid aminotransferase inhibitors
has_related_synonym: 4-aminobutyric acid aminotransferase inhibitor
has_related_synonym: 4-aminobutyric acid aminotransferase inhibitors
definition: An EC 2.6.1.* (transaminase) inhibitor that interferes with the action of 4-aminobutyrate--2-oxoglutarate transaminase (EC 2.6.1.19).
id: CHEBI:63674
has_related_synonym: EC 2.6.1.19 (4-aminobutyrate--2-oxoglutarate transaminase) inhibitors
has_related_synonym: EC 2.6.1.19 inhibitor
has_related_synonym: EC 2.6.1.19 inhibitors
has_related_synonym: GABA aminotransferase inhibitor
has_related_synonym: GABA aminotransferase inhibitors
has_related_synonym: GABA transaminase inhibitor
has_related_synonym: GABA transaminase inhibitors
has_related_synonym: GABA transferase inhibitor
has_related_synonym: GABA transferase inhibitors
has_related_synonym: GABA--2-oxoglutarate aminotransferase inhibitor
has_related_synonym: GABA--2-oxoglutarate aminotransferase inhibitors
has_related_synonym: GABA--2-oxoglutarate transaminase inhibitor
has_related_synonym: GABA--2-oxoglutarate transaminase inhibitors
has_related_synonym: GABA--alpha-ketoglutarate aminotransferase inhibitors
has_related_synonym: GABA--alpha-ketoglutarate transaminase inhibitor
has_related_synonym: GABA--alpha-ketoglutarate transaminase inhibitors
has_related_synonym: GABA--alpha-ketoglutaric acid transaminase inhibitor
has_related_synonym: GABA--alpha-ketoglutaric acid transaminase inhibitors
has_related_synonym: GABA--alpha-oxoglutarate aminotransferase inhibitor
has_related_synonym: GABA--alpha-oxoglutarate aminotransferase inhibitors
has_related_synonym: GABA--oxoglutarate aminotransferase inhibitor
has_related_synonym: GABA--oxoglutarate aminotransferase inhibitors
has_related_synonym: GABA--oxoglutarate transaminase inhibitor
has_related_synonym: GABA--oxoglutarate transaminase inhibitors
has_related_synonym: GabT inhibitor
has_related_synonym: GabT inhibitors
database_cross_reference: Wikipedia:4-aminobutyrate_transaminase
has_related_synonym: aminobutyrate aminotransferase inhibitor
has_related_synonym: aminobutyrate aminotransferase inhibitors
has_related_synonym: aminobutyrate transaminase inhibitor
has_related_synonym: aminobutyrate transaminase inhibitors
has_related_synonym: beta-alanine aminotransferase inhibitor
has_related_synonym: beta-alanine aminotransferase inhibitors
has_related_synonym: beta-alanine--oxoglutarate aminotransferase inhibitor
has_related_synonym: beta-alanine--oxoglutarate aminotransferase inhibitors
has_related_synonym: beta-alanine--oxoglutarate transaminase inhibitor
has_related_synonym: beta-alanine--oxoglutarate transaminase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: gamma-amino-N-butyrate transaminase inhibitor
has_related_synonym: gamma-amino-N-butyrate transaminase inhibitors
has_related_synonym: gamma-aminobutyrate aminotransaminase inhibitor
has_related_synonym: gamma-aminobutyrate aminotransaminase inhibitors
has_related_synonym: gamma-aminobutyrate transaminase inhibitor
has_related_synonym: gamma-aminobutyrate transaminase inhibitors
has_related_synonym: gamma-aminobutyrate--alpha-ketoglutarate aminotransferase inhibitor
has_related_synonym: gamma-aminobutyrate--alpha-ketoglutarate aminotransferase inhibitors
has_related_synonym: gamma-aminobutyrate--alpha-ketoglutarate transaminase inhibitor
has_related_synonym: gamma-aminobutyrate--alpha-ketoglutarate transaminase inhibitors
has_related_synonym: gamma-aminobutyrate:alpha-oxoglutarate aminotransferase inhibitor
has_related_synonym: gamma-aminobutyrate:alpha-oxoglutarate aminotransferase inhibitors
has_related_synonym: gamma-aminobutyric acid aminotransferase inhibitor
has_related_synonym: gamma-aminobutyric acid aminotransferase inhibitors
has_related_synonym: gamma-aminobutyric acid pyruvate transaminase inhibitor
has_related_synonym: gamma-aminobutyric acid pyruvate transaminase inhibitors
has_related_synonym: gamma-aminobutyric acid transaminase inhibitor

EC 2.1.1.45 (thymidylate synthase) inhibitor
type: Class
subclass of: EC 2.1.1.* (methyltransferases) inhibitor
has_related_synonym: 5,10-methylenetetrahydrofolate:dUMP C-methyltransferase inhibitor
has_related_synonym: 5,10-methylenetetrahydrofolate:dUMP C-methyltransferase inhibitors
definition: An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of thymidylate synthase (EC 2.1.1.45).
id: CHEBI:63720
has_related_synonym: EC 2.1.1.45 (thymidylate synthase) inhibitors
has_related_synonym: EC 2.1.1.45 inhibitor
has_related_synonym: EC 2.1.1.45 inhibitors
has_related_synonym: TMP synthetase inhibitor
has_related_synonym: TMP synthetase inhibitors
database_cross_reference: Wikipedia:Thymidylate_synthase_inhibitor
has_obo_namespace: chebi_ontology
has_related_synonym: dTMP synthase inhibitor
has_related_synonym: dTMP synthase inhibitors
has_related_synonym: methylenetetrahydrofolate:dUMP C-methyltransferase inhibitor
has_related_synonym: methylenetetrahydrofolate:dUMP C-methyltransferase inhibitors
has_related_synonym: thymidylate synthase inhibitor
has_related_synonym: thymidylate synthase inhibitors
has_related_synonym: thymidylate synthetase inhibitor
has_related_synonym: thymidylate synthetase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.1.2.2 (phosphoribosylglycinamide formyltransferase) inhibitor
type: Class
subclass of: EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor
has_related_synonym: 10-formyltetrahydrofolate:5'-phosphoribosylglycinamide N-formyltransferase inhibitors
has_related_synonym: 2-amino-N-ribosylacetamide 5'-phosphate transformylase inhibitor
has_related_synonym: 5,10-methenyltetrahydrofolate:2-amino-N-ribosylacetamide ribonucleotide transformylase inhibitor
has_related_synonym: 5,10-methenyltetrahydrofolate:2-amino-N-ribosylacetamide ribonucleotide transformylase inhibitors
definition: An EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor that interferes with the action of phosphoribosylglycinamide formyltransferase (EC 2.1.2.2).
id: CHEBI:63721
has_related_synonym: EC 2.1.2.2 (phosphoribosylglycinamide formyltransferase) inhibitors
has_related_synonym: EC 2.1.2.2 inhibitor
has_related_synonym: EC 2.1.2.2 inhibitors
has_related_synonym: GAR TFase inhibitor
has_related_synonym: GAR TFase inhibitors
has_related_synonym: GAR formyltransferase inhibitor
has_related_synonym: GAR formyltransferase inhibitors
has_related_synonym: GAR transformylase inhibitor
has_related_synonym: GAR transformylase inhibitors
database_cross_reference: Wikipedia:Phosphoribosylglycinamide_formyltransferase
has_obo_namespace: chebi_ontology
has_related_synonym: glycinamide ribonucleotide formyltransferase inhibitor
has_related_synonym: glycinamide ribonucleotide formyltransferase inhibitors
has_related_synonym: glycinamide ribonucleotide transformylase inhibitor
has_related_synonym: glycinamide ribonucleotide transformylase inhibitors
has_related_synonym: phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) inhibitor
has_related_synonym: phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) inhibitors
has_related_synonym: phosphoribosylglycinamide formyltransferase inhibitor
has_related_synonym: phosphoribosylglycinamide formyltransferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

neuroprotective agent
type: Class
subclass of: protective agent
definition: Any compound that can be used for the treatment of neurodegenerative disorders.
id: CHEBI:63726
has_obo_namespace: chebi_ontology
has_related_synonym: neuroprotectant
has_related_synonym: neuroprotectants
has_related_synonym: neuroprotective agents
in_subset: 3 STAR
imported from: chebi.owl

retinoid X receptor agonist
type: Class
subclass of: agonist
definition: An agonist that selectively binds to and activates a retinoid X receptor.
id: CHEBI:63794
database_cross_reference: Wikipedia:Retinoid_X_receptor
has_obo_namespace: chebi_ontology
has_related_synonym: retinoid X receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

film-forming compound
type: Class
subclass of: chemical role
definition: Any compound that leaves a pliable, cohesive, and continuous covering over a surface when applied to it.
id: CHEBI:63908
has_obo_namespace: chebi_ontology
has_related_synonym: film-forming agent
has_related_synonym: film-forming agents
has_related_synonym: film-forming compounds
in_subset: 3 STAR
imported from: chebi.owl

sclerotherapy agent
type: Class
subclass of: biological role
definition: A sclerotherapy agent is used to treat blood vessels or blood vessel malformations (vascular malformations) and also those of the lymphatic system by injection into the vessels, which makes them shrink.
id: CHEBI:63923
has_obo_namespace: chebi_ontology
has_related_synonym: sclerotherapy agents
in_subset: 3 STAR
imported from: chebi.owl

EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitor
type: Class
subclass of: EC 1.14.16.* (oxidoreductase acting on paired donors, reduced pteridine as one donor, incorporating 1 atom of oxygen) inhibitor
definition: An EC 1.14.16.* (oxidoreductase acting on paired donors, reduced pteridine as one donor, incorporating 1 atom of oxygen) inhibitor that interferes with the action of tyrosine 3-monooxygenase (EC 1.14.16.2).
id: CHEBI:63932
has_related_synonym: EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitors
has_related_synonym: EC 1.14.16.2 inhibitor
has_related_synonym: EC 1.14.16.2 inhibitors
has_related_synonym: L-tyrosine hydroxylase inhibitor
has_related_synonym: L-tyrosine hydroxylase inhibitors
has_related_synonym: L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating) inhibitor
has_related_synonym: L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating) inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: tyrosine 3-hydroxylase inhibitor
has_related_synonym: tyrosine 3-hydroxylase inhibitors
has_related_synonym: tyrosine 3-monooxygenase (EC 1.14.16.2) inhibitor
has_related_synonym: tyrosine 3-monooxygenase (EC 1.14.16.2) inhibitors
has_related_synonym: tyrosine 3-monooxygenase inhibitor
has_related_synonym: tyrosine 3-monooxygenase inhibitors
has_related_synonym: tyrosine hydroxylase inhibitor
has_related_synonym: tyrosine hydroxylase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

alpha1B-adrenoceptor antagonist
type: Class
subclass of: antagonist
definition: An antagonist at the alpha1B-adrenoceptor.
id: CHEBI:63936
has_related_synonym: alpha1B-adrenoceptor antagonists
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

estrogen receptor agonist
type: Class
subclass of: agonist
definition: An agonist at the estrogen receptor.
id: CHEBI:63951
has_obo_namespace: chebi_ontology
has_related_synonym: estrogen receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

adenosine A1 receptor antagonist
type: Class
subclass of: adenosine receptor antagonist
definition: An antagonist at the A1 receptor.
id: CHEBI:63957
database_cross_reference: Wikipedia:Adenosine_A1_receptor
has_related_synonym: adenosine A1 receptor antagonists
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

cellulose synthesis inhibitor
type: Class
subclass of: pathway inhibitor
definition: An pathway inhibitor that inhibits the synthesis of cellulose.
id: CHEBI:63958
has_related_synonym: cellulose biosynthesis inhibitor
has_related_synonym: cellulose biosynthesis inhibitors
has_related_synonym: cellulose synthesis inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

Hsp90 inhibitor
type: Class
subclass of: EC 3.6.4.10 (non-chaperonin molecular chaperone ATPase) inhibitor
definition: An EC 3.6.4.10 (non-chaperonin molecular chaperone ATPase) inhibitor that blocks the action of heat shock protein 90.
id: CHEBI:63962
has_related_synonym: Hsp90 inhibitors
database_cross_reference: PMID:19860732
database_cross_reference: PMID:19946660
database_cross_reference: PMID:22035754
database_cross_reference: PMID:22920907
database_cross_reference: PMID:22959035
database_cross_reference: PMID:23160336
database_cross_reference: PMID:23312026
database_cross_reference: Wikipedia:Hsp90_inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: heat shock protein 90 inhibitor
has_related_synonym: heat shock protein 90 inhibitors
in_subset: 3 STAR
imported from: chebi.owl

metabotropic glutamate receptor antagonist
type: Class
subclass of: antagonist
definition: An antagonist at the metabotropic glutamate receptor.
id: CHEBI:63963
has_obo_namespace: chebi_ontology
has_related_synonym: mGluR antagonist
has_related_synonym: mGluR antagonists
has_related_synonym: metabotropic glutamate receptor antagonists
in_subset: 3 STAR
imported from: chebi.owl

protein kinase C agonist
type: Class
subclass of: protein kinase agonist
definition: An agonist that selectively binds to and activates a protein kinase C receptor
id: CHEBI:64018
has_obo_namespace: chebi_ontology
has_related_synonym: protein kinase C agonists
in_subset: 3 STAR
imported from: chebi.owl

EC 3.5.1.99 (fatty acid amide hydrolase) inhibitor
type: Class
subclass of: EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor
definition: An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of fatty acid amide hydrolase (EC 3.5.1.99).
id: CHEBI:64033
has_related_synonym: EC 3.5.1.99 (fatty acid amide hydrolase) inhibitors
has_related_synonym: EC 3.5.1.99 inhibitor
has_related_synonym: EC 3.5.1.99 inhibitors
has_related_synonym: FAAH inhibitor
has_related_synonym: FAAH inhibitors
database_cross_reference: PMID:8083191
has_related_synonym: anandamide amidohydrolase inhibitor
has_related_synonym: anandamide amidohydrolase inhibitors
has_related_synonym: arachidonoylethanolamide amidohydrolase inhibitor
has_related_synonym: arachidonoylethanolamide amidohydrolase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: fatty acid amide hydrolase (EC 3.5.1.99) inhibitor
has_related_synonym: fatty acid amide hydrolase (EC 3.5.1.99) inhibitors
has_related_synonym: fatty acid amide hydrolase inhibitor
has_related_synonym: fatty acid amide hydrolase inhibitors
has_related_synonym: fatty acylamide amidohydrolase inhibitor
has_related_synonym: fatty acylamide amidohydrolase inhibitors
has_related_synonym: oleamide hydrolase inhibitor
has_related_synonym: oleamide hydrolase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

food additive
type: Class
subclass of: application
subclass of: food component
definition: Any substance which is added to food to preserve or enhance its flavour and/or appearance.
id: CHEBI:64047
database_cross_reference: Wikipedia:Food_additive
has_obo_namespace: chebi_ontology
has_related_synonym: food additives
in_subset: 3 STAR
imported from: chebi.owl

food acidity regulator
type: Class
subclass of: food additive
definition: A food additive that is used to change or otherwise control the acidity or alkalinity of foods. They may be acids, bases, neutralising agents or buffering agents.
id: CHEBI:64049
database_cross_reference: Wikipedia:Acidity_regulator
has_related_synonym: acidity regulator
has_related_synonym: acidity regulators
has_obo_namespace: chebi_ontology
has_related_synonym: food acidity regulators
has_related_synonym: pH control agent
has_related_synonym: pH control agents
in_subset: 3 STAR
imported from: chebi.owl

delta-opioid receptor agonist
type: Class
subclass of: delta-opioid agent
subclass of: opioid receptor agonist
definition: A compound that exhibits agonist activity at the delta-opioid receptor.
id: CHEBI:64054
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

incretin mimetic
type: Class
subclass of: biological role
definition: Any compound that mimics the action of incretins, gastrointestinal hormones that cause an increase in the amount of insulin released from the beta cells of the islets of Langerhans after eating, even before blood glucose levels become elevated.
id: CHEBI:64088
has_obo_namespace: chebi_ontology
has_related_synonym: incretin mimetics
in_subset: 3 STAR
imported from: chebi.owl

AMPA receptor agonist
type: Class
subclass of: agonist
has_related_synonym: AMPA receptor agonists
has_related_synonym: AMPAR agonist
definition: An agonist that selectively binds to and activates AMPA receptors.
id: CHEBI:64102
database_cross_reference: Wikipedia:AMPA_receptor
has_related_synonym: alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor agonist
has_obo_namespace: chebi_ontology
has_related_synonym: quisqualate receptor agonist
in_subset: 3 STAR
imported from: chebi.owl

protein kinase G agonist
type: Class
subclass of: protein kinase agonist
definition: An agonist that selectively binds to and activates a protein kinase G receptor.
id: CHEBI:64105
has_obo_namespace: chebi_ontology
has_related_synonym: protein kinase G agonists
in_subset: 3 STAR
imported from: chebi.owl

protein kinase agonist
type: Class
subclass of: agonist
definition: An agonist that selectively binds to and activates a protein kinase receptor.
id: CHEBI:64106
has_obo_namespace: chebi_ontology
has_related_synonym: protein kinase agonists
in_subset: 3 STAR
imported from: chebi.owl

EC 2.5.1.58 (protein farnesyltransferase) inhibitor
type: Class
subclass of: EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor
definition: An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of protein farnesyltransferase (EC 2.5.1.58), one of the three enzymes in the prenyltransferase group.
id: CHEBI:64133
has_related_synonym: EC 2.5.1.58 (protein farnesyltransferase) inhibitors
has_related_synonym: EC 2.5.1.58 inhibitor
has_related_synonym: EC 2.5.1.58 inhibitors
has_related_synonym: FTase inhibitor
has_related_synonym: FTase inhibitors
database_cross_reference: Wikipedia:Farnesyltransferase
has_obo_namespace: chebi_ontology
has_related_synonym: farnesyl transferase inhibitor
has_related_synonym: farnesyl transferase inhibitors
has_related_synonym: farnesyl-diphosphate:protein-cysteine farnesyltransferase inhibitor
has_related_synonym: farnesyl-diphosphate:protein-cysteine farnesyltransferase inhibitors
has_related_synonym: farnesyltransferase inhibitor
has_related_synonym: farnesyltransferase inhibitors
has_related_synonym: protein farnesyltransferase (EC 2.5.1.58) inhibitor
has_related_synonym: protein farnesyltransferase (EC 2.5.1.58) inhibitors
has_related_synonym: protein farnesyltransferase inhibitor
has_related_synonym: protein farnesyltransferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

cysteine protease inhibitor
type: Class
subclass of: protease inhibitor
subclass of: EC 3.4.22.* (cysteine endopeptidase) inhibitor
definition: Any protease inhibitor that restricts the action of a cysteine protease.
id: CHEBI:64152
has_obo_namespace: chebi_ontology
has_related_synonym: cysteine protease inhibitors
has_related_synonym: cysteine proteinase inhibitor
has_related_synonym: cysteine proteinase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

H3-receptor agonist
type: Class
subclass of: histamine agonist
definition: A histamine agonist that binds to and activates histamine H3-receptors.
id: CHEBI:64154
has_related_synonym: H3-receptor agonists
has_obo_namespace: chebi_ontology
has_related_synonym: histamine H3-receptor agonist
has_related_synonym: histamine H3-receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

H4-receptor agonist
type: Class
subclass of: histamine agonist
definition: A histamine agonist that binds to and activates H4-receptors.
id: CHEBI:64155
has_related_synonym: H4-receptor agonists
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

H3-receptor antagonist
type: Class
subclass of: histamine antagonist
definition: A histamine antagonist that selectively binds to but does not activate histamine H3 receptors, thereby blocking the actions of endogenous histamine.
id: CHEBI:64176
has_related_synonym: H3-receptor antagonists
has_obo_namespace: chebi_ontology
has_related_synonym: histamine H3-receptor antagonist
has_related_synonym: histamine H3-receptor antagonists
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.8.15 (UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase) inhibitor
type: Class
subclass of: EC 2.7.8.* (transferases for other substituted phosphate groups) inhibitor
definition: An EC 2.7.8.* (transferases for other substituted phosphate groups) inhibitor that interferes with the action of any UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.15), preventing formation of N-acetylglucosamine lipid intermediates and glycosylation of newly synthesised glycoproteins.
id: CHEBI:64237
has_related_synonym: EC 2.7.8.15 (UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase) inhibitors
has_related_synonym: EC 2.7.8.15 inhibitor
has_related_synonym: EC 2.7.8.15 inhibitors
has_related_synonym: GlcNAc-1-P transferase inhibitor
has_related_synonym: GlcNAc-1-P transferase inhibitors
has_related_synonym: N-acetylglucosamine phosphotransferase inhibitor
has_related_synonym: N-acetylglucosamine transferase inhibitors
has_related_synonym: N-acetylglucosamine-1-phosphate transferase inhibitor
has_related_synonym: N-acetylglucosamine-1-phosphate transferase inhibitors
has_related_synonym: UDP-D-N-acetylglucosamine N-acetylglucosamine 1-phosphate transferase inhibitor
has_related_synonym: UDP-D-N-acetylglucosamine N-acetylglucosamine 1-phosphate transferase inhibitors
has_related_synonym: UDP-GlcNAc:dolichyl-phosphate GlcNAc-1-phosphate transferase inhibitor
has_related_synonym: UDP-GlcNAc:dolichyl-phosphate GlcNAc-1-phosphate transferase inhibitors
has_related_synonym: UDP-N-acetyl-D-glucosamine:dolichol phosphate N-acetyl-D-glucosamine-1-phosphate transferase inhibitor
has_related_synonym: UDP-N-acetyl-D-glucosamine:dolichol phosphate N-acetyl-D-glucosamine-1-phosphate transferase inhibitors
has_related_synonym: UDP-N-acetyl-D-glucosamine:dolichyl-phosphate N-acetyl-D-glucosaminephosphotransferase inhibitor
has_related_synonym: UDP-N-acetyl-D-glucosamine:dolichyl-phosphate N-acetyl-D-glucosaminephosphotransferase inhibitors
has_related_synonym: UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.15) inhibitor
has_related_synonym: UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.15) inhibitors
has_related_synonym: UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase inhibitor
has_related_synonym: UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase inhibitors
has_related_synonym: UDP-acetylglucosamine--dolichol phosphate acetylglucosamine phosphotransferase inhibitor
has_related_synonym: UDP-acetylglucosamine--dolichol phosphate acetylglucosamine phosphotransferase inhibitors
has_related_synonym: UDP-acetylglucosamine--dolichol phosphate acetylglucosamine-1-phosphotransferase inhibitor
has_related_synonym: UDP-acetylglucosamine--dolichol phosphate acetylglucosamine-1-phosphotransferase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: chitobiosylpyrophosphoryldolichol synthase inhibitor
has_related_synonym: chitobiosylpyrophosphoryldolichol synthase inhibitors
has_related_synonym: dolichol phosphate N-acetylglucosamine-1-phosphotransferase inhibitor
has_related_synonym: dolichol phosphate N-acetylglucosamine-1-phosphotransferase inhibitors
has_related_synonym: uridine diphosphoacetylglucosamine--dolichyl phosphate acetylglucosamine-1-phosphotransferase inhibitor
has_related_synonym: uridine diphosphoacetylglucosamine--dolichyl phosphate acetylglucosamine-1-phosphotransferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

reaction intermediate
type: Class
subclass of: chemical role
definition: Any chemical substance produced during the conversion of a reactant to a product.
id: CHEBI:64297
database_cross_reference: Wikipedia:Reaction_intermediate
has_obo_namespace: chebi_ontology
has_related_synonym: chemical intermediate
in_subset: 3 STAR
imported from: chebi.owl

K-ATP channel agonist
type: Class
subclass of: agonist
definition: A compound which acts as an agonist at the ATP-sensitive K+ channel.
has_related_synonym: ATP-sensitive K(+) channel agonist
has_related_synonym: ATP-sensitive K(+) channel agonists
has_related_synonym: ATP-sensitive K+ channel agonist
has_related_synonym: ATP-sensitive K+ channel agonists
has_related_synonym: ATP-sensitive K+ channel opener
has_related_synonym: ATP-sensitive K+ channel openers
id: CHEBI:64338
has_related_synonym: K(ATP) channel agonist
has_related_synonym: K(ATP) channel agonists
has_related_synonym: K-ATP channel agonists
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

MALDI matrix material
type: Class
subclass of: application
has_related_synonym: 'matrix-assisted laser desorption/ionization' matrix material
has_related_synonym: 'matrix-assisted laser desorption/ionization' matrix materials
definition: A compound used to form the matrix for MALDI (matrix-assisted laser desorption/ionization) mass spectrometry. MALDI matrix materials are crystalline compounds with a fairly low molecular weight, so as to allow facile vaporization, have strong absorption at UV or IR wavelengths (to rapidly and efficiently absorb laser irradiation), generally contain polar groups (enabling them to be used in aqueous solutions) and are frequently acidic (so assisting ionisation of the compound being studied, which is contained within the matrix material).
id: CHEBI:64345
has_related_synonym: MALDI matrix materials
has_related_synonym: MALDI matrix solution
has_related_synonym: MALDI matrix solutions
database_cross_reference: PMID:15373456
database_cross_reference: Patent:EP2060919
database_cross_reference: Wikipedia:Matrix-assisted_laser_desorption/ionization#Matrix
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

glutamate transporter activator
type: Class
subclass of: neurotransmitter transporter modulator
definition: A neurotransmitter transporter modulator that activates glutamate transporters.
id: CHEBI:64370
has_obo_namespace: chebi_ontology
has_related_synonym: excitatory amino-acid transporter activator
has_related_synonym: excitatory amino-acid transporter activators
has_related_synonym: glutamate transporter activators
in_subset: 3 STAR
imported from: chebi.owl

neurotransmitter transporter modulator
type: Class
subclass of: neurotransmitter agent
subclass of: membrane transport modulator
definition: A membrane transport modulator that affects the transport of neurotransmitters.
id: CHEBI:64371
has_obo_namespace: chebi_ontology
has_related_synonym: neurotransmitter transporter modulators
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.22.38 (cathepsin K) inhibitor
type: Class
subclass of: cysteine protease inhibitor
subclass of: EC 3.4.22.* (cysteine endopeptidase) inhibitor
definition: A cysteine protease inhibitor which inhibits cathepsin K (EC 3.4.22.38).
id: CHEBI:64406
has_related_synonym: EC 3.4.22.38 (cathepsin K) inhibitors
has_related_synonym: EC 3.4.22.38 inhibitor
has_related_synonym: EC 3.4.22.38 inhibitors
database_cross_reference: Wikipedia:Cathepsin_K
has_related_synonym: cathepsin K (EC 3.4.22.38) inhibitor
has_related_synonym: cathepsin K (EC 3.4.22.38) inhibitors
has_related_synonym: cathepsin K inhibitor
has_related_synonym: cathepsin K inhibitors
has_related_synonym: cathepsin O inhibitor
has_related_synonym: cathepsin O inhibitors
has_related_synonym: cathepsin O2 inhibitor
has_related_synonym: cathepsin O2 inhibitors
has_related_synonym: cathepsin X inhibitor
has_related_synonym: cathepsin X inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 2.5.1.29 (geranylgeranyl diphosphate synthase) inhibitor
type: Class
subclass of: EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor
has_related_synonym: (2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase inhibitor
has_related_synonym: (2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase inhibitors
definition: An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of geranylgeranyl diphosphate synthase (EC 2.5.1.29).
id: CHEBI:64411
has_related_synonym: EC 2.5.1.29 (geranylgeranyl diphosphate synthase) inhibitors
has_related_synonym: EC 2.5.1.29 inhibitor
has_related_synonym: EC 2.5.1.29 inhibitors
has_related_synonym: GGPP synthase inhibitor
has_related_synonym: GGPP synthase inhibitors
database_cross_reference: Patent:EP1280891
database_cross_reference: Patent:US2002004218
has_obo_namespace: chebi_ontology
has_related_synonym: farnesyltransferase inhibitor
has_related_synonym: farnesyltransferase inhibitors
has_related_synonym: geranylgeranyl diphosphate synthase (EC 2.5.1.29) inhibitor
has_related_synonym: geranylgeranyl diphosphate synthase (EC 2.5.1.29) inhibitors
has_related_synonym: geranylgeranyl diphosphate synthase inhibitor
has_related_synonym: geranylgeranyl diphosphate synthase inhibitors
has_related_synonym: geranylgeranyl pyrophosphate synthase inhibitor
has_related_synonym: geranylgeranyl pyrophosphate synthase inhibitors
has_related_synonym: geranylgeranyl pyrophosphate synthetase inhibitor
has_related_synonym: geranylgeranyl pyrophosphate synthetase inhibitors
has_related_synonym: geranylgeranyl-PP synthetase inhibitor
has_related_synonym: geranylgeranyl-PP synthetase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.3.1.43 (arogenate dehydrogenase) inhibitor
type: Class
subclass of: EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor
definition: An EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor, NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of arogenate dehydrogenase (EC 1.3.1.43).
id: CHEBI:64416
has_related_synonym: EC 1.3.1.43 (arogenate dehydrogenase) inhibitors
has_related_synonym: EC 1.3.1.43 inhibitor
has_related_synonym: EC 1.3.1.43 inhibitors
has_related_synonym: L-arogenate:NAD(+) oxidoreductase (decarboxylating) inhibitor
has_related_synonym: L-arogenate:NAD(+) oxidoreductase (decarboxylating) inhibitors
has_related_synonym: L-arogenate:NAD+ oxidoreductase (decarboxylating) inhibitor
has_related_synonym: L-arogenate:NAD+ oxidoreductase (decarboxylating) inhibitors
has_related_synonym: L-arogenate:NAD+ oxidoreductase inhibitor
has_related_synonym: L-arogenate:NAD+ oxidoreductase inhibitors
has_related_synonym: TyrA(a) inhibitor
has_related_synonym: TyrA(a) inhibitors
database_cross_reference: Wikipedia:Arogenate_dehydrogenase
has_related_synonym: arogenate dehydrogenase (EC 1.3.1.43) inhibitor
has_related_synonym: arogenate dehydrogenase (EC 1.3.1.43) inhibitors
has_related_synonym: arogenate dehydrogenase inhibitor
has_related_synonym: arogenate dehydrogenase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: cyclohexadienyl dehydrogenase inhibitor
has_related_synonym: cyclohexadienyl dehydrogenase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

monolignol
type: Class
subclass of: plant metabolite
definition: A metabolite of plant origin (phytochemical) which acts as a source material for biosynthesis of both lignans and lignin.
id: CHEBI:64477
database_cross_reference: Wikipedia:Monolignol
has_obo_namespace: chebi_ontology
has_related_synonym: monolignols
in_subset: 3 STAR
imported from: chebi.owl

EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor
type: Class
subclass of: EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor
has_related_synonym: 5,10-methylenetetrahydrofolate:glycine hydroxymethyltransferase inhibitor
has_related_synonym: 5,10-methylenetetrahydrofolate:glycine hydroxymethyltransferase inhibitors
definition: An EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor that interferes with the action of glycine hydroxymethyltransferase (EC 2.1.2.1).
id: CHEBI:64570
has_related_synonym: EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitors
has_related_synonym: EC 2.1.2.1 inhibitor
has_related_synonym: EC 2.1.2.1 inhibitors
has_related_synonym: L-serine hydroxymethyltransferase inhibitor
has_related_synonym: L-serine hydroxymethyltransferase inhibitors
has_related_synonym: L-threonine aldolase inhibitor
has_related_synonym: L-threonine aldolase inhibitors
database_cross_reference: Wikipedia:Glycine_hydroxymethyltransferase
has_related_synonym: allothreonine aldolase inhibitor
has_related_synonym: allothreonine aldolase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: glycine hydroxymethyltransferase (EC 2.1.2.1) inhibitor
has_related_synonym: glycine hydroxymethyltransferase (EC 2.1.2.1) inhibitors
has_related_synonym: glycine hydroxymethyltransferase inhibitor
has_related_synonym: glycine hydroxymethyltransferase inhibitors
has_related_synonym: serine aldolase inhibitor
has_related_synonym: serine aldolase inhibitors
has_related_synonym: serine hydroxymethylase inhibitor
has_related_synonym: serine hydroxymethylase inhibitors
has_related_synonym: serine hydroxymethyltransferase inhibitor
has_related_synonym: serine hydroxymethyltransferase inhibitors
has_related_synonym: serine transhydroxymethylase inhibitor
has_related_synonym: serine transhydroxymethylase inhibitors
has_related_synonym: threonine aldolase inhibitor
has_related_synonym: threonine aldolase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

NMDA receptor agonist
type: Class
subclass of: excitatory amino acid agonist
definition: An excitatory amino acid agonist which binds to NMDA receptors and triggers a response.
id: CHEBI:64571
has_related_synonym: N-methyl-D-aspartate receptor agonist
has_related_synonym: N-methyl-D-aspartate receptor agonists
has_related_synonym: NMDA receptor agonists
has_related_synonym: NMDAR agonist
has_related_synonym: NMDAR agonists
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

flour treatment agent
type: Class
subclass of: food additive
definition: A food additive which is added to flour or dough to improve baking quality and/or colour.
id: CHEBI:64577
database_cross_reference: Wikipedia:Flour_treatment_agent
has_obo_namespace: chebi_ontology
has_related_synonym: dough improver
has_related_synonym: dough improvers
has_exact_synonym: flour treatment agent
has_related_synonym: improving agent
has_related_synonym: improving agents
in_subset: 3 STAR
imported from: chebi.owl

uremic toxin
type: Class
subclass of: toxin
definition: A toxin that accumulates in patients with chronic kidney disease.
id: CHEBI:64584
database_cross_reference: Wikipedia:Uremic_toxin
has_obo_namespace: chebi_ontology
has_related_synonym: uremic toxins
in_subset: 3 STAR
imported from: chebi.owl

glycine transporter 1 inhibitor
type: Class
subclass of: glycine transporter inhibitor
definition: Any glycine transporter inhibitor that interferes with the action of glycine 1 transporters.
id: CHEBI:64588
has_related_synonym: GlyT1 inhibitor
has_related_synonym: GlyT1 inhibitors
database_cross_reference: PMID:17504107
database_cross_reference: PMID:18758757
database_cross_reference: PMID:20678516
database_cross_reference: PMID:21141920
database_cross_reference: PMID:21531289
database_cross_reference: PMID:22177408
database_cross_reference: Wikipedia:Glycine_transporter_1
has_obo_namespace: chebi_ontology
has_related_synonym: glycine transporter 1 inhibitors
in_subset: 3 STAR
imported from: chebi.owl

glycine receptor agonist
type: Class
subclass of: agonist
definition: An agonist that binds to and activates glycine receptors
id: CHEBI:64589
has_obo_namespace: chebi_ontology
has_related_synonym: glycine receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

EC 1.8.1.9 (thioredoxin reductase) inhibitor
type: Class
subclass of: EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD(+) or NADP(+) as acceptor) inhibitor
definition: An EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of thioredoxin reductase (EC 1.8.1.9).
id: CHEBI:64670
has_related_synonym: EC 1.8.1.9 (thioredoxin reductase) inhibitors
has_related_synonym: EC 1.8.1.9 inhibitor
has_related_synonym: EC 1.8.1.9 inhibitors
has_related_synonym: NADP-thioredoxin reductase inhibitor
has_related_synonym: NADP-thioredoxin reductase inhibitors
has_related_synonym: NADPH-thioredoxin reductase inhibitor
has_related_synonym: NADPH-thioredoxin reductase inhibitors
has_related_synonym: NADPH2:oxidized thioredoxin oxidoreductase inhibitor
has_related_synonym: NADPH2:oxidized thioredoxin oxidoreductase inhibitors
has_related_synonym: TrxR inhibitor
has_related_synonym: TrxR inhibitors
database_cross_reference: Wikipedia:Thioredoxin_reductase
has_obo_namespace: chebi_ontology
has_related_synonym: thioredoxin reductase (EC 1.8.1.9) inhibitor
has_related_synonym: thioredoxin reductase (EC 1.8.1.9) inhibitors
has_related_synonym: thioredoxin reductase (NADPH) inhibitor
has_related_synonym: thioredoxin reductase (NADPH) inhibitors
has_related_synonym: thioredoxin reductase inhibitor
has_related_synonym: thioredoxin reductase inhibitors
has_related_synonym: thioredoxin-disulfide reductase inhibitor
has_related_synonym: thioredoxin-disulfide reductase inhibitors
has_related_synonym: thioredoxin:NADP+ oxidoreductase inhibitor
has_related_synonym: thioredoxin:NADP+ oxidoreductase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.3.1.26 (sterol O-acyltransferase) inhibitor
type: Class
subclass of: EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor
has_related_synonym: ACAT inhibitor
has_related_synonym: ACAT inhibitors
definition: An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of acyl-CoA:cholesterol acyltransferase (EC 2.3.1.26).
id: CHEBI:64696
has_related_synonym: EC 2.3.1.26 (sterol O-acyltransferase) inhibitors
has_related_synonym: EC 2.3.1.26 inhibitor
has_related_synonym: EC 2.3.1.26 inhibitors
database_cross_reference: Wikipedia:Sterol_O-acyltransferase
has_related_synonym: acyl coenzyme A-cholesterol-O-acyltransferase inhibitor
has_related_synonym: acyl coenzyme A-cholesterol-O-acyltransferase inhibitors
has_related_synonym: acyl-CoA:cholesterol O-acyltransferase inhibitor
has_related_synonym: acyl-CoA:cholesterol acyltransferase inhibitor
has_related_synonym: acyl-CoA:cholesterol acyltransferase inhibitors
has_related_synonym: acylcoenzyme A:cholesterol O-acyltransferase inhibitor
has_related_synonym: acylcoenzyme A:cholesterol O-acyltransferase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: cholesterol acyltransferase inhibitor
has_related_synonym: cholesterol acyltransferase inhibitors
has_related_synonym: cholesterol ester synthase inhibitor
has_related_synonym: cholesterol ester synthase inhibitors
has_related_synonym: cholesterol ester synthetase inhibitor
has_related_synonym: cholesterol ester synthetase inhibitors
has_related_synonym: cholesteryl ester synthetase inhibitor
has_related_synonym: cholesteryl ester synthetase inhibitors
has_related_synonym: sterol O-acyltransferase (EC 2.3.1.26) inhibitor
has_related_synonym: sterol O-acyltransferase (EC 2.3.1.26) inhibitors
has_related_synonym: sterol O-acyltransferase inhibitor
has_related_synonym: sterol O-acyltransferase inhibitors
has_related_synonym: sterol-ester synthase inhibitor
has_related_synonym: sterol-ester synthase inhibitors
has_related_synonym: sterol-ester synthetase inhibitor
has_related_synonym: sterol-ester synthetase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

acyl-CoA:cholesterol acyltransferase 2 inhibitor
type: Class
subclass of: EC 2.3.1.26 (sterol O-acyltransferase) inhibitor
definition: A sterol O-acyltransferase inhibitor that specifically inhibits acyl-CoA:cholesterol acyltransferase 2.
has_related_synonym: ACAT-2 inhibitor
has_related_synonym: ACAT-2 inhibitors
id: CHEBI:64697
has_related_synonym: acyl-CoA:cholesterol acyltransferase 2 inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 3.1.4.11 (phosphoinositide phospholipase C) inhibitor
type: Class
subclass of: EC 3.1.4.* (phosphoric diester hydrolase) inhibitor
has_related_synonym: 1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase inhibitor
has_related_synonym: 1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase inhibitors
has_related_synonym: 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase inhibitor
has_related_synonym: 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase inhibitors
has_related_synonym: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase inhibitor
has_related_synonym: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase inhibitors
definition: An EC 3.1.4.* (phosphoric diester hydrolase) inhibitor that interferes with the action of phosphatidylinositol-specific phospholipase C (EC 3.1.4.11).
id: CHEBI:64763
has_related_synonym: EC 3.1.4.11 (phosphoinositide phospholipase C) inhibitors
has_related_synonym: EC 3.1.4.11 inhibitor
has_related_synonym: EC 3.1.4.11 inhibitors
has_related_synonym: PI-PLC inhibitor
has_related_synonym: PI-PLC inhibitors
database_cross_reference: Wikipedia:Phosphatidylinositol-specific_phospholipase_C
has_obo_namespace: chebi_ontology
has_related_synonym: monophosphatidylinositol phosphodiesterase inhibitor
has_related_synonym: monophosphatidylinositol phosphodiesterase inhibitors
has_related_synonym: phosphatidylinositol phospholipase C inhibitor
has_related_synonym: phosphatidylinositol phospholipase C inhibitors
has_related_synonym: phosphatidylinositol-specific phospholipase C inhibitor
has_related_synonym: phosphatidylinositol-specific phospholipase C inhibitors
has_related_synonym: phosphoinositidase C inhibitor
has_related_synonym: phosphoinositidase C inhibitors
has_related_synonym: phosphoinositide phospholipase C (EC 3.1.4.11) inhibitor
has_related_synonym: phosphoinositide phospholipase C (EC 3.1.4.11) inhibitors
has_related_synonym: phosphoinositide phospholipase C inhibitor
has_related_synonym: phosphoinositide phospholipase C inhibitors
has_related_synonym: triphosphoinositide phosphodiesterase inhibitor
has_related_synonym: triphosphoinositide phosphodiesterase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

cosmetic
type: Class
subclass of: application
id: CHEBI:64857
definition: The role played by a substance in enhancing the appearance or odour of the human body; a name given to the substance itself or to a component of it.
database_cross_reference: Wikipedia:Cosmetics
has_obo_namespace: chebi_ontology
has_related_synonym: cosmetic component
has_related_synonym: cosmetics
in_subset: 3 STAR
imported from: chebi.owl

poison
type: Class
subclass of: biological role
definition: Any substance that causes disturbance to organisms by chemical reaction or other activity on the molecular scale, when a sufficient quantity is absorbed by the organism.
id: CHEBI:64909
database_cross_reference: Wikipedia:Poison
has_obo_namespace: chebi_ontology
has_related_synonym: poisonous agent
has_related_synonym: poisonous agents
has_related_synonym: poisonous substance
has_related_synonym: poisonous substances
has_related_synonym: poisons
has_related_synonym: toxic agent
has_related_synonym: toxic agents
has_related_synonym: toxic substance
has_related_synonym: toxic substances
in_subset: 3 STAR
imported from: chebi.owl

antimitotic
type: Class
subclass of: pharmacological role
definition: Any compound that inhibits cell division (mitosis).
id: CHEBI:64911
database_cross_reference: Wikipedia:Mitotic_inhibitor
has_related_synonym: antimitotics
has_obo_namespace: chebi_ontology
has_related_synonym: mitosis inhibitor
has_related_synonym: mitosis inhibitors
has_related_synonym: mitotic inhibitor
has_related_synonym: mitotic inhibitors
in_subset: 3 STAR
imported from: chebi.owl

antimycobacterial drug
type: Class
subclass of: antibacterial drug
definition: A drug used to treat or prevent infections caused by Mycobacteria, a genus of actinobacteria. Aerobic and nonmotile, members of the genus include the pathogens responsible for causing tuberculosis and leprosy.
id: CHEBI:64912
has_related_synonym: antimycobacterial agent
has_related_synonym: antimycobacterial agents
has_related_synonym: antimycobacterial drugs
has_related_synonym: antimycobacterials
has_related_synonym: antimycobacterium
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

antiplasmodial drug
type: Class
subclass of: antiparasitic agent
subclass of: antiprotozoal drug
definition: An antiparasitic drug which is effective against Apicomplexan parasites in the genus Plasmodium. The genus contains over 200 species and includes those responsible for malaria.
id: CHEBI:64915
has_related_synonym: antiplasmodial agent
has_related_synonym: antiplasmodial agents
has_related_synonym: antiplasmodial drugs
has_related_synonym: antiplasmodium agent
has_related_synonym: antiplasmodium agents
has_related_synonym: antiplasmodium drug
has_related_synonym: antiplasmodium drugs
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 2.3.1.20 (diacylglycerol O-acyltransferase) inhibitor
type: Class
subclass of: EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor
has_related_synonym: 1,2-diacylglycerol acyltransferase inhibitor
has_related_synonym: 1,2-diacylglycerol acyltransferase inhibitors
definition: An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of diacylglycerol O-acyltransferase (EC 2.3.1.20).
id: CHEBI:64919
has_related_synonym: DGAT inhibitor
has_related_synonym: DGAT inhibitors
has_related_synonym: EC 2.3.1.20 (diacylglycerol O-acyltransferase) inhibitors
has_related_synonym: EC 2.3.1.20 inhibitor
has_related_synonym: EC 2.3.1.20 inhibitors
database_cross_reference: Wikipedia:Dgat
has_related_synonym: acyl-CoA:1,2-diacylglycerol O-acyltransferase inhibitor
has_related_synonym: acyl-CoA:1,2-diacylglycerol O-acyltransferase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: diacylglycerol O-acyltransferase (EC 2.3.1.20) inhibitor
has_related_synonym: diacylglycerol O-acyltransferase (EC 2.3.1.20) inhibitors
has_related_synonym: diacylglycerol O-acyltransferase inhibitor
has_related_synonym: diacylglycerol O-acyltransferase inhibitors
has_related_synonym: diacylglycerol acyltransferase inhibitor
has_related_synonym: diacylglycerol acyltransferase inhibitors
has_related_synonym: diglyceride O-acyltransferase inhibitor
has_related_synonym: diglyceride O-acyltransferase inhibitors
has_related_synonym: diglyceride acyltransferase inhibitor
has_related_synonym: diglyceride acyltransferase inhibitors
has_related_synonym: palmitoyl-CoA-sn-1,2-diacylglycerol acyltransferase inhibitor
has_related_synonym: palmitoyl-CoA-sn-1,2-diacylglycerol acyltransferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 6.5.1.1 [DNA ligase (ATP)] inhibitor
type: Class
subclass of: EC 6.5.1.* (DNA/RNA repair enzymes) inhibitor
definition: An EC 6.5.1.* (DNA/RNA repair enzymes) inhibitor that interferes with the action of DNA ligase (ATP), EC 6.5.1.1.
id: CHEBI:64920
has_related_synonym: DNA joinase inhibitor
has_related_synonym: DNA joinase inhibitors
has_related_synonym: DNA ligase (ATP) (EC 6.5.1.1) inhibitor
has_related_synonym: DNA ligase (ATP) (EC 6.5.1.1) inhibitors
has_related_synonym: DNA ligase (ATP) inhibitor
has_related_synonym: DNA ligase inhibitor
has_related_synonym: DNA ligase inhibitors
has_related_synonym: DNA repair enzyme inhibitor
has_related_synonym: DNA repair enzyme inhibitors
has_related_synonym: DNA-joining enzyme inhibitor
has_related_synonym: DNA-joining enzyme inhibitors
has_related_synonym: EC 6.5.1.1 (DNA ligase (ATP)) inhibitor
has_related_synonym: EC 6.5.1.1 (DNA ligase (ATP)) inhibitors
has_related_synonym: EC 6.5.1.1 [DNA ligase (ATP)] inhibitors
has_related_synonym: EC 6.5.1.1 inhibitor
has_related_synonym: EC 6.5.1.1 inhibitors
database_cross_reference: Wikipedia:Dna_Ligase
has_obo_namespace: chebi_ontology
has_related_synonym: deoxyribonucleate ligase inhibitor
has_related_synonym: deoxyribonucleate ligase inhibitors
has_related_synonym: deoxyribonucleic acid joinase inhibitor
has_related_synonym: deoxyribonucleic acid joinase inhibitors
has_related_synonym: deoxyribonucleic acid ligase inhibitor
has_related_synonym: deoxyribonucleic acid ligase inhibitors
has_related_synonym: deoxyribonucleic acid repair enzyme inhibitor
has_related_synonym: deoxyribonucleic acid repair enzyme inhibitors
has_related_synonym: deoxyribonucleic acid-joining enzyme inhibitor
has_related_synonym: deoxyribonucleic acid-joining enzyme inhibitors
has_related_synonym: deoxyribonucleic joinase inhibitor
has_related_synonym: deoxyribonucleic joinase inhibitors
has_related_synonym: deoxyribonucleic ligase inhibitor
has_related_synonym: deoxyribonucleic ligase inhibitors
has_related_synonym: deoxyribonucleic repair enzyme inhibitor
has_related_synonym: deoxyribonucleic repair enzyme inhibitors
has_related_synonym: deoxyribonucleic-joining enzyme inhibitor
has_related_synonym: deoxyribonucleic-joining enzyme inhibitors
has_related_synonym: polydeoxyribonucleotide synthase (ATP) inhibitor
has_related_synonym: sealase inhibitor
has_related_synonym: sealase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.21.37 (leukocyte elastase) inhibitor
type: Class
subclass of: EC 3.4.21.* (serine endopeptidase) inhibitor
definition: An EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the activity of leukocyte elastase (EC 3.4.21.37).
id: CHEBI:64922
has_related_synonym: EC 3.4.21.37 (leukocyte elastase) inhibitors
has_related_synonym: EC 3.4.21.37 inhibitor
has_related_synonym: EC 3.4.21.37 inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: elastase inhibitor
has_related_synonym: elastase inhibitors
has_related_synonym: elaszym inhibitor
has_related_synonym: elaszym inhibitors
has_related_synonym: granulocyte elastase inhibitor
has_related_synonym: granulocyte elastase inhibitors
has_related_synonym: leukocyte elastase (EC 3.4.21.37) inhibitor
has_related_synonym: leukocyte elastase (EC 3.4.21.37) inhibitors
has_related_synonym: leukocyte elastase inhibitor
has_related_synonym: lysosomal elastase inhibitor
has_related_synonym: lysosomal elastase inhibitors
has_related_synonym: neutrophil elastase inhibitor
has_related_synonym: neutrophil elastase inhibitors
has_related_synonym: polymorphonuclear leukocyte elastase inhibitor
has_related_synonym: polymorphonuclear leukocyte elastase inhibitors
has_related_synonym: serine elastase inhibitor
has_related_synonym: serine elastase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

hepatitis C protease inhibitor
type: Class
subclass of: protease inhibitor
definition: An inhibitor of hepatitis C protease, an enzyme required for production of proteins needed for viral assembly.
id: CHEBI:64924
has_obo_namespace: chebi_ontology
has_related_synonym: hepatitis C protease inhibitors
in_subset: 3 STAR
imported from: chebi.owl

serine protease inhibitor
type: Class
subclass of: protease inhibitor
definition: Any protease inhibitor that restricts the action of a serine protease.
id: CHEBI:64926
has_obo_namespace: chebi_ontology
has_related_synonym: serine protease inhibitors
has_related_synonym: serine proteinase inhibitor
has_related_synonym: serine proteinase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

cathepsin B inhibitor
type: Class
subclass of: cysteine protease inhibitor
definition: A cysteine protease inhibitor which inhibits cathepsin B (EC 3.4.22.1).
id: CHEBI:64932
has_related_synonym: EC 3.4.22.1 inhibitor
has_related_synonym: EC 3.4.22.1 inhibitors
has_related_synonym: cathepsin B inhibitors
has_related_synonym: cathepsin B1 inhibitor
has_related_synonym: cathepsin B1 inhibitors
has_related_synonym: cathepsin II inhibitor
has_related_synonym: cathepsin II inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

melanin synthesis inhibitor
type: Class
subclass of: depigmentation drug
definition: A depigmentation agent which inhibits the synthesis of melanin.
id: CHEBI:64933
has_obo_namespace: chebi_ontology
has_related_synonym: melanin biosynthesis inhibitor
has_related_synonym: melanin biosynthesis inhibitors
has_related_synonym: melanin synthesis inhibitors
has_related_synonym: melanogenesis inhibitor
has_related_synonym: melanogenesis inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.21.1 (chymotrypsin) inhibitor
type: Class
subclass of: EC 3.4.21.* (serine endopeptidase) inhibitor
definition: An EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of chymotrypsin (EC 3.4.21.1).
id: CHEBI:64943
has_related_synonym: EC 3.4.21.1 (chymotrypsin) inhibitors
has_related_synonym: EC 3.4.21.1 inhibitor
has_related_synonym: EC 3.4.21.1 inhibitors
database_cross_reference: Wikipedia:Chymotrypsin
has_related_synonym: alpha-chymar inhibitor
has_related_synonym: alpha-chymar inhibitors
has_related_synonym: alpha-chymar ophth inhibitor
has_related_synonym: alpha-chymar ophth inhibitors
has_related_synonym: alpha-chymotrypsin inhibitor
has_related_synonym: alpha-chymotrypsin inhibitors
has_related_synonym: avazyme inhibitor
has_related_synonym: avazyme inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: chymar inhibitor
has_related_synonym: chymar inhibitors
has_related_synonym: chymotest inhibitor
has_related_synonym: chymotest inhibitors
has_related_synonym: chymotrypsin (EC 3.4.21.1) inhibitor
has_related_synonym: chymotrypsin (EC 3.4.21.1) inhibitors
has_related_synonym: chymotrypsin inhibitor
has_related_synonym: chymotrypsin inhibitors
has_related_synonym: chymotrypsins A and B inhibitor
has_related_synonym: chymotrypsins A and B inhibitors
has_related_synonym: chymotrypsins A inhibitor
has_related_synonym: chymotrypsins A inhibitors
has_related_synonym: chymotrypsins B inhibitor
has_related_synonym: chymotrypsins B inhibitors
has_related_synonym: enzeon inhibitor
has_related_synonym: enzeon inhibitors
has_related_synonym: quimar inhibitor
has_related_synonym: quimar inhibitors
has_related_synonym: quimotrase inhibitor
has_related_synonym: quimotrase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

anti-HIV agent
type: Class
subclass of: antiviral agent
definition: An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus.
id: CHEBI:64946
has_related_synonym: anti-AIDS agent
has_related_synonym: anti-AIDS agents
has_related_synonym: anti-HIV agents
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

anti-HIV-1 agent
type: Class
subclass of: anti-HIV agent
definition: An anti-HIV agent that destroys or inhibits the replication of HIV-1, the more infective and more virulent of the two types of HIV virus.
id: CHEBI:64947
has_related_synonym: anti-HIV-1 agents
has_related_synonym: anti-HTLV-III agent
has_related_synonym: anti-HTLV-III agents
has_related_synonym: anti-LAV agent
has_related_synonym: anti-LAV agents
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

anti-HIV-2 agent
type: Class
subclass of: anti-HIV agent
definition: An anti-HIV agent that destroys or inhibits the replication of HIV-2, the less infective and less virulent of the two types of HIV virus.
id: CHEBI:64949
has_related_synonym: anti-HIV-2 agents
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

anti-HBV agent
type: Class
subclass of: antiviral agent
definition: An antiviral agent that destroys or inhibits the replication of the hepatitis B virus.
id: CHEBI:64951
database_cross_reference: PMID:20712567
has_related_synonym: anti-HBV agents
has_related_synonym: anti-hepatitis B virus agent
has_related_synonym: anti-hepatitis B virus agents
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

anti-HSV agent
type: Class
subclass of: antiviral agent
definition: An antiviral agent that destroys or inhibits the replication of the herpes simplex virus (also known as the human herpes virus).
id: CHEBI:64952
database_cross_reference: Wikipedia:Herpes_simplex_virus
has_related_synonym: anti-HHV agent
has_related_synonym: anti-HHV agents
has_related_synonym: anti-HSV agents
has_related_synonym: anti-herpes simplex virus agent
has_related_synonym: anti-herpes simplex virus agents
has_related_synonym: anti-human herpes virus agent
has_related_synonym: anti-human herpes virus agents
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

anti-HSV-1 agent
type: Class
subclass of: anti-HSV agent
definition: An anti-HSV agent agent that destroys or inhibits the replication of herpes simplex virus-1.
id: CHEBI:64953
has_related_synonym: anti-HHV-1 agent
has_related_synonym: anti-HHV-1 agents
has_related_synonym: anti-HHV-I agent
has_related_synonym: anti-HHV-I agents
has_related_synonym: anti-HSV-1 agents
has_related_synonym: anti-HSV-I agent
has_related_synonym: anti-HSV-I agents
has_related_synonym: anti-human herpes virus-1 agent
has_related_synonym: anti-human herpes virus-1 agents
has_related_synonym: anti-human herpes virus-I agent
has_related_synonym: anti-human herpes virus-I agents
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

anti-HSV-2 agent
type: Class
subclass of: anti-HSV agent
definition: An anti-HSV agent agent that destroys or inhibits the replication of herpes simplex virus-2.
id: CHEBI:64954
has_related_synonym: anti-HHV-2 agent
has_related_synonym: anti-HHV-2 agents
has_related_synonym: anti-HHV-II agent
has_related_synonym: anti-HHV-II agents
has_related_synonym: anti-HSV-2 agents
has_related_synonym: anti-HSV-II agent
has_related_synonym: anti-HSV-II agents
has_related_synonym: anti-human herpes virus-2 agent
has_related_synonym: anti-human herpes virus-2 agents
has_related_synonym: anti-human herpes virus-II agent
has_related_synonym: anti-human herpes virus-II agents
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 3.2.1.166 (heparanase) inhibitor
type: Class
subclass of: EC 3.2.1.* (glycosidase) inhibitor
definition: An EC 3.2.1.* (glycosidase) inhibitor that interferes with the action of heparanase (EC 3.2.1.166).
has_related_synonym: C1A heparanase inhibitor
has_related_synonym: C1A heparanase inhibitors
id: CHEBI:64955
has_related_synonym: EC 3.2.1.166 (heparanase) inhibitors
has_related_synonym: HPSE inhibitor
has_related_synonym: HPSE inhibitors
has_related_synonym: Hpa1 heparanase inhibitor
has_related_synonym: Hpa1 heparanase inhibitors
has_related_synonym: Hpa1 inhibitor
has_related_synonym: Hpa1 inhibitors
database_cross_reference: Wikipedia:Heparanase
has_obo_namespace: chebi_ontology
has_related_synonym: heparan sulfate N-sulfo-D-glucosamine endoglucanase inhibitor
has_related_synonym: heparan sulfate N-sulfo-D-glucosamine endoglucanase inhibitors
has_related_synonym: heparanase (EC 3.2.1.166) inhibitor
has_related_synonym: heparanase (EC 3.2.1.166) inhibitors
has_related_synonym: heparanase 1 inhibitor
has_related_synonym: heparanase 1 inhibitors
has_related_synonym: heparanase inhibitor
has_related_synonym: heparanase inhibitors
has_related_synonym: heparanase-1 inhibitor
has_related_synonym: heparanase-1 inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.21.39 (chymase) inhibitor
type: Class
subclass of: protease inhibitor
subclass of: EC 3.4.21.* (serine endopeptidase) inhibitor
definition: An EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of chymase (EC 3.4.21.39).
id: CHEBI:64957
has_related_synonym: EC 3.4.21.39 (chymase) inhibitors
has_related_synonym: EC 3.4.21.39 inhibitor
has_related_synonym: EC 3.4.21.39 inhibitors
has_related_synonym: SK protease inhibitor
has_related_synonym: SK protease inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: chymase (EC 3.4.21.39) inhibitor
has_related_synonym: chymase (EC 3.4.21.39) inhibitors
has_related_synonym: chymase inhibitor
has_related_synonym: chymase inhibitors
has_related_synonym: mast cell protease I inhibitor
has_related_synonym: mast cell protease I inhibitors
has_related_synonym: skeletal muscle (SK) protease inhibitor
has_related_synonym: skeletal muscle (SK) protease inhibitors
has_related_synonym: skeletal muscle protease inhibitor
has_related_synonym: skeletal muscle protease inhibitors
has_related_synonym: skin chymotryptic proteinase inhibitor
has_related_synonym: skin chymotryptic proteinase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor
type: Class
subclass of: lipoxygenase inhibitor
subclass of: EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitor
has_related_synonym: 5-LOX inhibitor
has_related_synonym: 5-LOX inhibitors
has_related_synonym: 5-lipoxygenase inhibitor
has_related_synonym: 5-lipoxygenase inhibitors
has_related_synonym: 5delta-lipoxygenase inhibitor
has_related_synonym: 5delta-lipoxygenase inhibitors
definition: A lipoxygenase inhibitor that interferes with the action of arachidonate 5-lipoxygenase (EC 1.13.11.34).
has_related_synonym: C-5-lipoxygenase inhibitor
has_related_synonym: C-5-lipoxygenase inhibitors
id: CHEBI:64964
has_related_synonym: EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitors
has_related_synonym: EC 1.13.11.34 inhibitor
has_related_synonym: EC 1.13.11.34 inhibitors
has_related_synonym: LTA synthase inhibitor
has_related_synonym: LTA synthase inhibitors
has_related_synonym: arachidonate 5-lipoxygenase (EC 1.13.11.34) inhibitor
has_related_synonym: arachidonate 5-lipoxygenase (EC 1.13.11.34) inhibitors
has_related_synonym: arachidonate 5-lipoxygenase inhibitor
has_related_synonym: arachidonate 5-lipoxygenase inhibitors
has_related_synonym: arachidonic 5-lipoxygenase inhibitor
has_related_synonym: arachidonic 5-lipoxygenase inhibitors
has_related_synonym: arachidonic acid 5-lipoxygenase inhibitor
has_related_synonym: arachidonic acid 5-lipoxygenase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: delta(5)-lipoxygenase inhibitor
has_related_synonym: delta(5)-lipoxygenase inhibitors
has_related_synonym: leukotriene A4 synthase inhibitor
has_related_synonym: leukotriene A4 synthase inhibitors
has_related_synonym: leukotriene-A4 synthase inhibitor
has_related_synonym: leukotriene-A4 synthase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitor
type: Class
subclass of: lipoxygenase inhibitor
has_related_synonym: 12-LOX inhibitor
has_related_synonym: 12-LOX inhibitors
has_related_synonym: 12-lipoxygenase inhibitor
has_related_synonym: 12-lipoxygenase inhibitors
has_related_synonym: 12S-lipoxygenase inhibitor
has_related_synonym: 12S-lipoxygenase inhibitors
has_related_synonym: 5delta-lipoxygenase inhibitor
has_related_synonym: 5delta-lipoxygenase inhibitors
definition: A lipoxygenase inhibitor that interferes with the action of arachidonate 12-lipoxygenase (EC 1.13.11.31).
has_related_synonym: C-5-lipoxygenase inhibitor
has_related_synonym: C-5-lipoxygenase inhibitors
id: CHEBI:64995
has_related_synonym: EC 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitors
has_related_synonym: EC 1.13.11.31 inhibitor
has_related_synonym: EC 1.13.11.31 inhibitors
has_related_synonym: LTA4 synthase inhibitor
has_related_synonym: LTA4 synthase inhibitors
has_related_synonym: arachidonate 12-lipoxygenase (EC 1.13.11.31) inhibitor
has_related_synonym: arachidonate 12-lipoxygenase (EC 1.13.11.31) inhibitors
has_related_synonym: arachidonate 12-lipoxygenase inhibitor
has_related_synonym: arachidonate 12-lipoxygenase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: delta(12)-lipoxygenase inhibitor
has_related_synonym: delta(12)-lipoxygenase inhibitors
has_related_synonym: leukotriene A4 synthase inhibitor
has_related_synonym: leukotriene A4 synthase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor
type: Class
subclass of: lipoxygenase inhibitor
subclass of: EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitor
has_related_synonym: 15-LOX inhibitor
has_related_synonym: 15-LOX inhibitors
has_related_synonym: 15-lipoxygenase inhibitor
has_related_synonym: 15-lipoxygenase inhibitors
definition: A lipoxygenase inhibitor that interferes with the action of arachidonate 15-lipoxygenase (EC 1.13.11.33).
id: CHEBI:64996
has_related_synonym: EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitors
has_related_synonym: EC 1.13.11.33 inhibitor
has_related_synonym: EC 1.13.11.33 inhibitors
database_cross_reference: Wikipedia:ALOX15
has_related_synonym: arachidonate 15-lipoxygenase (EC 1.13.11.33) inhibitor
has_related_synonym: arachidonate 15-lipoxygenase (EC 1.13.11.33) inhibitors
has_related_synonym: arachidonate 15-lipoxygenase inhibitor
has_related_synonym: arachidonate 15-lipoxygenase inhibitors
has_related_synonym: arachidonate:oxygen 15-oxidoreductase inhibitor
has_related_synonym: arachidonate:oxygen 15-oxidoreductase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: linoleic acid omega(6)-lipoxygenase inhibitor
has_related_synonym: linoleic acid omega(6)-lipoxygenase inhibitors
has_related_synonym: omega(6) lipoxygenase inhibitor
has_related_synonym: omega(6) lipoxygenase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.1.1.3 (triacylglycerol lipase) inhibitor
type: Class
subclass of: EC 3.1.1.* (carboxylic ester hydrolase) inhibitor
definition: Any EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that inhibits the action of triacylglycerol lipase (EC 3.1.1.3).
id: CHEBI:65001
has_related_synonym: EC 3.1.1.3 (triacylglycerol lipase) inhibitors
has_related_synonym: EC 3.1.1.3 inhibitor
has_related_synonym: EC 3.1.1.3 inhibitors
has_related_synonym: GEH inhibitor
has_related_synonym: GEH inhibitors
has_related_synonym: PPL inhibitor
has_related_synonym: PPL inhibitors
has_related_synonym: Tween hydrolase inhibitor
has_related_synonym: Tween hydrolase inhibitors
has_related_synonym: Tweenase inhibitor
has_related_synonym: Tweenase inhibitors
has_related_synonym: Tweenesterase inhibitor
has_related_synonym: Tweenesterase inhibitors
has_related_synonym: butyrinase inhibitor
has_related_synonym: butyrinase inhibitors
has_related_synonym: cacordase inhibitor
has_related_synonym: cacordase inhibitors
has_related_synonym: capalase L inhibitor
has_related_synonym: capalase L inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: glycerol ester hydrolase inhibitor
has_related_synonym: glycerol ester hydrolase inhibitors
has_related_synonym: glycerol-ester hydrolase inhibitor
has_related_synonym: glycerol-ester hydrolase inhibitors
has_related_synonym: heparin releasable hepatic lipase inhibitor
has_related_synonym: heparin releasable hepatic lipase inhibitors
has_related_synonym: hepatic lipase inhibitor
has_related_synonym: hepatic lipase inhibitors
has_related_synonym: hepatic monoacylglycerol acyltransferase inhibitor
has_related_synonym: hepatic monoacylglycerol acyltransferase inhibitors
has_related_synonym: lipase inhibitor
has_related_synonym: lipase inhibitors
has_related_synonym: lipazin inhibitor
has_related_synonym: lipazin inhibitors
has_related_synonym: liver lipase inhibitor
has_related_synonym: liver lipase inhibitors
has_related_synonym: pancreatic lipase inhibitor
has_related_synonym: pancreatic lipase inhibitors
has_related_synonym: pancreatic triacylglycerol lipase inhibitor
has_related_synonym: pancreatic triacylglycerol lipase inhibitors
has_related_synonym: post-heparin plasma protamine-resistant lipase inhibitor
has_related_synonym: post-heparin plasma protamine-resistant lipase inhibitors
has_related_synonym: salt-resistant post-heparin lipase inhibitor
has_related_synonym: salt-resistant post-heparin lipase inhibitors
has_related_synonym: steapsin inhibitor
has_related_synonym: steapsin inhibitors
has_related_synonym: triacetinase inhibitor
has_related_synonym: triacetinase inhibitors
has_related_synonym: triacylglycerol ester hydrolase inhibitor
has_related_synonym: triacylglycerol ester hydrolase inhibitors
has_related_synonym: triacylglycerol lipase (EC 3.1.1.3) inhibitor
has_related_synonym: triacylglycerol lipase (EC 3.1.1.3) inhibitors
has_related_synonym: triacylglycerol lipase inhibitor
has_related_synonym: triacylglycerol lipase inhibitors
has_related_synonym: tributyrase inhibitor
has_related_synonym: tributyrase inhibitors
has_related_synonym: tributyrin esterase inhibitor
has_related_synonym: tributyrin esterase inhibitors
has_related_synonym: tributyrinase inhibitor
has_related_synonym: tributyrinase inhibitors
has_related_synonym: triglyceridase inhibitor
has_related_synonym: triglyceridase inhibitors
has_related_synonym: triglyceride hydrolase inhibitor
has_related_synonym: triglyceride hydrolase inhibitors
has_related_synonym: triglyceride lipase inhibitor
has_related_synonym: triglyceride lipase inhibitors
has_related_synonym: triolein hydrolase inhibitor
has_related_synonym: triolein hydrolase inhibitors
has_related_synonym: tween-hydrolysing esterase inhibitor
has_related_synonym: tween-hydrolyzing esterase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

anti-asthmatic agent
type: Class
subclass of: application
definition: Any compound that has anti-asthmatic effects.
id: CHEBI:65023
has_related_synonym: anti-asthmatic agents
has_related_synonym: antiasthmatic agent
has_related_synonym: antiasthmatic agents
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 4.1.1.19 (arginine decarboxylase) inhibitor
type: Class
subclass of: EC 4.1.1.* (carboxy-lyase) inhibitor
has_related_synonym: ADC inhibitor
has_related_synonym: ADC inhibitors
definition: An EC 4.1.1.* (carboxy-lyase) inhibitor that interferes with the action of arginine decarboxylase (EC 4.1.1.19).
id: CHEBI:65053
has_related_synonym: EC 4.1.1.19 (arginine decarboxylase) inhibitors
has_related_synonym: EC 4.1.1.19 inhibitor
has_related_synonym: EC 4.1.1.19 inhibitors
has_related_synonym: L-arginine carboxy-lyase (agmatine-forming) inhibitor
has_related_synonym: L-arginine carboxy-lyase (agmatine-forming) inhibitors
has_related_synonym: L-arginine carboxy-lyase inhibitor
has_related_synonym: L-arginine carboxy-lyase inhibitors
has_related_synonym: SpeA inhibitor
has_related_synonym: SpeA inhibitors
has_related_synonym: arginine decarboxylase (EC 4.1.1.19) inhibitor
has_related_synonym: arginine decarboxylase (EC 4.1.1.19) inhibitors
has_related_synonym: arginine decarboxylase inhibitor
has_related_synonym: arginine decarboxylase inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 3.1.3.11 (fructose-bisphosphatase) inhibitor
type: Class
subclass of: EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor
definition: An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of fructose-bisphosphatase (EC 3.1.3.11).
id: CHEBI:65056
has_related_synonym: D-fructose 1,6-diphosphatase inhibitor
has_related_synonym: D-fructose 1,6-diphosphatase inhibitors
has_related_synonym: D-fructose-1,6-bisphosphate 1-phosphohydrolase inhibitor
has_related_synonym: D-fructose-1,6-bisphosphate 1-phosphohydrolase inhibitors
has_related_synonym: D-fructose-1,6-bisphosphate phosphatase inhibitor
has_related_synonym: D-fructose-1,6-bisphosphate phosphatase inhibitors
has_related_synonym: EC 3.1.3.11 (fructose-bisphosphatase) inhibitors
has_related_synonym: EC 3.1.3.11 inhibitor
has_related_synonym: EC 3.1.3.11 inhibitors
has_related_synonym: FBPase inhibitor
has_related_synonym: FBPase inhibitors
database_cross_reference: Wikipedia:Fructose_1,6-bisphosphatase
has_obo_namespace: chebi_ontology
has_related_synonym: fructose 1,6-bisphosphatase inhibitor
has_related_synonym: fructose 1,6-bisphosphatase inhibitors
has_related_synonym: fructose 1,6-bisphosphate 1-phosphatase inhibitor
has_related_synonym: fructose 1,6-bisphosphate 1-phosphatase inhibitors
has_related_synonym: fructose 1,6-bisphosphate phosphatase inhibitor
has_related_synonym: fructose 1,6-bisphosphate phosphatase inhibitors
has_related_synonym: fructose 1,6-diphosphatase inhibitor
has_related_synonym: fructose 1,6-diphosphatase inhibitors
has_related_synonym: fructose 1,6-diphosphate phosphatase inhibitor
has_related_synonym: fructose 1,6-diphosphate phosphatase inhibitors
has_related_synonym: fructose bisphosphate phosphatase inhibitor
has_related_synonym: fructose bisphosphate phosphatase inhibitors
has_related_synonym: fructose diphosphatase inhibitor
has_related_synonym: fructose diphosphatase inhibitors
has_related_synonym: fructose diphosphate phosphatase inhibitor
has_related_synonym: fructose diphosphate phosphatase inhibitors
has_related_synonym: fructose-bisphosphatase (EC 3.1.3.11) inhibitor
has_related_synonym: fructose-bisphosphatase (EC 3.1.3.11) inhibitors
has_related_synonym: fructose-bisphosphatase inhibitor
has_related_synonym: fructose-bisphosphatase inhibitors
has_related_synonym: hexose bisphosphatase inhibitor
has_related_synonym: hexose bisphosphatase inhibitors
has_related_synonym: hexose diphosphatase inhibitor
in_subset: 3 STAR
imported from: chebi.owl

adenosine A1 receptor agonist
type: Class
subclass of: adenosine receptor agonist
definition: An agonist at the A1 receptor.
id: CHEBI:65057
database_cross_reference: Wikipedia:Adenosine_A1_receptor
has_related_synonym: adenosine A1 receptor agonists
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 2.1.1.79 (cyclopropane-fatty-acyl-phospholipid synthase) inhibitor
type: Class
subclass of: EC 2.1.1.* (methyltransferases) inhibitor
definition: An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of cyclopropane fatty acid synthase (EC 2.1.1.79).
has_related_synonym: CFA synthase inhibitor
has_related_synonym: CFA synthase inhibitors
id: CHEBI:65064
has_related_synonym: EC 2.1.1.79 (cyclopropane-fatty-acyl-phospholipid synthase) inhibitors
has_related_synonym: EC 2.1.1.79 inhibitor
has_related_synonym: EC 2.1.1.79 inhibitors
has_related_synonym: S-adenosyl-L-methionine:unsaturated-phospholipid methyltransferase (cyclising) inhibitor
has_related_synonym: S-adenosyl-L-methionine:unsaturated-phospholipid methyltransferase (cyclising) inhibitors
has_related_synonym: S-adenosyl-L-methionine:unsaturated-phospholipid methyltransferase (cyclizing) inhibitor
has_related_synonym: S-adenosyl-L-methionine:unsaturated-phospholipid methyltransferase (cyclizing) inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: cyclopropane fatty acid synthase inhibitors
has_related_synonym: cyclopropane fatty acid synthetase inhibitor
has_related_synonym: cyclopropane fatty acid synthetase inhibitors
has_related_synonym: cyclopropane synthase inhibitor
has_related_synonym: cyclopropane synthase inhibitors
has_related_synonym: cyclopropane synthetase inhibitor
has_related_synonym: cyclopropane synthetase inhibitors
has_related_synonym: cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79) inhibitor
has_related_synonym: cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79) inhibitors
has_related_synonym: cyclopropane-fatty-acyl-phospholipid synthase inhibitor
has_related_synonym: cyclopropane-fatty-acyl-phospholipid synthase inhibitors
has_related_synonym: unsaturated-phospholipid methyltransferase inhibitor
has_related_synonym: unsaturated-phospholipid methyltransferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.1.1.72 [site-specific DNA-methyltransferase (adenine-specific)] inhibitor
type: Class
subclass of: EC 2.1.1.* (methyltransferases) inhibitor
definition: An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of site-specific DNA-methyltransferase (adenine-specific), EC 2.1.1.72.
id: CHEBI:65065
has_related_synonym: DNA adenine methyltransferase inhibitor
has_related_synonym: DNA adenine methyltransferase inhibitors
has_related_synonym: Dam inhibitor
has_related_synonym: Dam inhibitors
has_related_synonym: EC 2.1.1.72 (site-specific DNA-methyltransferase (adenine-specific)) inhibitor
has_related_synonym: EC 2.1.1.72 (site-specific DNA-methyltransferase (adenine-specific)) inhibitors
has_related_synonym: EC 2.1.1.72 [site-specific DNA-methyltransferase (adenine-specific)] inhibitors
has_related_synonym: EC 2.1.1.72 inhibitor
has_related_synonym: EC 2.1.1.72 inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: modification methylase inhibitor
has_related_synonym: modification methylase inhibitors
has_related_synonym: restriction-modification system inhibitor
has_related_synonym: restriction-modification system inhibitors
has_related_synonym: site-specific DNA-methyltransferase (adenine-specific) (EC 2.1.1.72) inhibitor
has_related_synonym: site-specific DNA-methyltransferase (adenine-specific) (EC 2.1.1.72) inhibitors
has_related_synonym: site-specific DNA-methyltransferase (adenine-specific) inhibitor
has_related_synonym: site-specific DNA-methyltransferase (adenine-specific) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

first generation antipsychotic
type: Class
subclass of: antipsychotic agent
definition: Antipsychotic drugs which can have different modes of action but which tend to be more likely than second generation antipsychotics to cause extrapyramidal motor control disabilities such as body rigidity or Parkinson's disease-type movements; such body movements can become permanent even after treatment has ceased.
id: CHEBI:65190
database_cross_reference: Wikipedia:Typical_antipsychotic
has_obo_namespace: chebi_ontology
has_related_synonym: first generation antipsychotic agent
has_related_synonym: first generation antipsychotic agents
has_related_synonym: first generation antipsychotic drug
has_related_synonym: first generation antipsychotic drugs
has_related_synonym: first generation antipsychotics
has_related_synonym: typical antipsychotic
has_related_synonym: typical antipsychotic agent
has_related_synonym: typical antipsychotic agents
has_related_synonym: typical antipsychotic drug
has_related_synonym: typical antipsychotic drugs
has_related_synonym: typical antipsychotics
in_subset: 3 STAR
imported from: chebi.owl

second generation antipsychotic
type: Class
subclass of: antipsychotic agent
definition: Antipsychotic drugs which can have different modes of action but which tend to be less likely than first generation antipsychotics to cause extrapyramidal motor control disabilities such as body rigidity or Parkinson's disease-type movements.
id: CHEBI:65191
has_related_synonym: atypical antipsychotic
has_related_synonym: atypical antipsychotic agent
has_related_synonym: atypical antipsychotic agents
has_related_synonym: atypical antipsychotic drug
has_related_synonym: atypical antipsychotic drugs
has_related_synonym: atypical antipsychotics
has_obo_namespace: chebi_ontology
has_related_synonym: second generation antipsychotic agent
has_related_synonym: second generation antipsychotic agents
has_related_synonym: second generation antipsychotic drug
has_related_synonym: second generation antipsychotic drugs
has_related_synonym: second generation antipsychotics
in_subset: 3 STAR
imported from: chebi.owl

vascular endothelial growth factor receptor antagonist
type: Class
subclass of: antagonist
definition: An antagonist at the vascular endothelial growth factor receptor.
id: CHEBI:65207
has_related_synonym: VEGF receptor inhibitor
has_related_synonym: VEGF receptor inhibitors
has_related_synonym: VEGFR inhibitor
has_related_synonym: VEGFR inhibitors
database_cross_reference: Wikipedia:VEGF_receptors
has_obo_namespace: chebi_ontology
has_related_synonym: vascular endothelial growth factor receptor antagonists
has_related_synonym: vascular endothelial growth factor receptor inhibitor
has_related_synonym: vascular endothelial growth factor receptor inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.21.5 (thrombin) inhibitor
type: Class
subclass of: EC 3.4.21.* (serine endopeptidase) inhibitor
definition: An EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of thrombin (EC 3.4.21.5).
id: CHEBI:65232
has_related_synonym: E thrombin inhibitor
has_related_synonym: E thrombin inhibitors
has_related_synonym: EC 3.4.21.5 (thrombin) inhibitors
has_related_synonym: EC 3.4.21.5 inhibitor
has_related_synonym: EC 3.4.21.5 inhibitors
has_related_synonym: activated blood-coagulation factor II inhibitor
has_related_synonym: activated blood-coagulation factor II inhibitors
has_related_synonym: beta-thrombin inhibitor
has_related_synonym: beta-thrombin inhibitors
has_related_synonym: blood-coagulation factor IIa inhibitor
has_related_synonym: blood-coagulation factor IIa inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: factor IIa inhibitor
has_related_synonym: factor IIa inhibitors
has_related_synonym: fibrinogenase inhibitor
has_related_synonym: fibrinogenase inhibitors
has_related_synonym: gamma-thrombin inhibitor
has_related_synonym: gamma-thrombin inhibitors
has_related_synonym: thrombase inhibitor
has_related_synonym: thrombase inhibitors
has_related_synonym: thrombin (EC 3.4.21.5) inhibitor
has_related_synonym: thrombin (EC 3.4.21.5) inhibitors
has_related_synonym: thrombin inhibitor
has_related_synonym: thrombin inhibitors
has_related_synonym: thrombin-C inhibitor
has_related_synonym: thrombin-C inhibitors
has_related_synonym: thrombofort inhibitor
has_related_synonym: thrombofort inhibitors
has_related_synonym: tropostasin inhibitor
has_related_synonym: tropostasin inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.2.1.114 (mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase) inhibitor
type: Class
subclass of: EC 3.2.1.* (glycosidase) inhibitor
has_related_synonym: (1->3)-(1->6)-mannosyl-oligosaccharide alpha-D-mannohydrolase inhibitor
has_related_synonym: (1->3)-(1->6)-mannosyl-oligosaccharide alpha-D-mannohydrolase inhibitors
has_related_synonym: 1,3(1,6)-alpha-D-mannosidase inhibitor
has_related_synonym: 1,3(1,6)-alpha-D-mannosidase inhibitors
has_related_synonym: 1,3-(1,6-)mannosyl-oligosaccharide alpha-D-mannohydrolase inhibitor
has_related_synonym: 1,3-(1,6-)mannosyl-oligosaccharide alpha-D-mannohydrolase inhibitors
definition: An enzyme inhibitor that interferes with the action of mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase (EC 3.2.1.114), a key enzyme target in the development of anti-cancer therapies.
id: CHEBI:65239
has_related_synonym: EC 3.2.1.114 (mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase) inhibitors
has_related_synonym: EC 3.2.1.114 inhibitor
has_related_synonym: EC 3.2.1.114 inhibitors
has_related_synonym: GlcNAc transferase I-dependent alpha1,3[alpha1,6]mannosidase inhibitor
has_related_synonym: GlcNAc transferase I-dependent alpha1,3[alpha1,6]mannosidase inhibitors
has_related_synonym: Golgi alpha-mannosidase II inhibitor
has_related_synonym: Golgi alpha-mannosidase II inhibitors
has_related_synonym: ManII inhibitor
has_related_synonym: ManII inhibitors
database_cross_reference: PMID:18759458
has_related_synonym: alpha-D-mannosidase II inhibitor
has_related_synonym: alpha-D-mannosidase II inhibitors
has_related_synonym: alpha-mannosidase II inhibitor
has_related_synonym: alpha-mannosidase II inhibitors
has_related_synonym: alpha1-3,6-mannosidase inhibitor
has_related_synonym: alpha1-3,6-mannosidase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: exo-1,3-1,6-alpha-mannosidase inhibitor
has_related_synonym: exo-1,3-1,6-alpha-mannosidase inhibitors
has_related_synonym: golgi alpha-mannosidase II inhibitor
has_related_synonym: golgi alpha-mannosidase II inhibitors
has_related_synonym: mannosidase II inhibitor
has_related_synonym: mannosidase II inhibitors
has_related_synonym: mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase (EC 3.2.1.114) inhibitor
has_related_synonym: mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase (EC 3.2.1.114) inhibitors
has_related_synonym: mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase inhibitor
has_related_synonym: mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

LRH-1 agonist
type: Class
subclass of: agonist
definition: An agonist that binds to and activates liver receptor homologue-1 (LRH-1).
id: CHEBI:65254
has_related_synonym: LRH-1 agonists
has_related_synonym: NR5A2 agonist
has_related_synonym: NR5A2 agonists
database_cross_reference: Wikipedia:Liver_receptor_homolog-1
has_obo_namespace: chebi_ontology
has_related_synonym: liver receptor homologue-1 agonist
has_related_synonym: liver receptor homologue-1 agonists
has_related_synonym: nuclear receptor subfamily 5 group A member 2 agonist
has_related_synonym: nuclear receptor subfamily 5 group A member 2 agonists
in_subset: 3 STAR
imported from: chebi.owl

food preservative
type: Class
subclass of: food additive
id: CHEBI:65255
definition: Substances which are added to food in order to prevent decomposition caused by microbial growth or by undesirable chemical changes.
has_obo_namespace: chebi_ontology
has_related_synonym: food preservatives
in_subset: 3 STAR
imported from: chebi.owl

antimicrobial food preservative
type: Class
subclass of: antimicrobial agent
subclass of: food preservative
definition: A food preservative which prevents decomposition of food by preventing the growth of fungi or bacteria. In European countries, E-numbers for permitted food preservatives are from E200 to E299, divided into sorbates (E200-209), benzoates (E210-219), sulfites (E220-229), phenols and formates (E230-239), nitrates (E240-259), acetates (E260-269), lactates (E270-279), propionates (E280-289) and others (E290-299).
id: CHEBI:65256
has_related_synonym: antimicrobial food preservatives
has_related_synonym: antimicrobial preservative
has_related_synonym: antimicrobial preservatives
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

GABA antagonist
type: Class
subclass of: antagonist
subclass of: GABA agent
definition: A compound that inhibits the action of gamma-aminobutyric acid.
id: CHEBI:65259
has_related_synonym: GABA antagonists
database_cross_reference: Wikipedia:GABA_antagonist
has_obo_namespace: chebi_ontology
has_related_synonym: gamma-aminobutyric acid receptor antagonist
has_related_synonym: gamma-aminobutyric acid receptor antagonists
in_subset: 3 STAR
imported from: chebi.owl

antacid
type: Class
subclass of: drug
subclass of: pharmacological role
definition: Any substance which is used to neutralise stomach acidity.
id: CHEBI:65265
database_cross_reference: Wikipedia:Antacid
has_related_synonym: antacids
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

erythropeotin receptor agonist
type: Class
subclass of: agonist
definition: An agonist that binds to and activates erythropeotin receptors.
id: CHEBI:66894
database_cross_reference: Wikipedia:Erythropoietin_receptor
has_obo_namespace: chebi_ontology
has_exact_synonym: erythropeotin receptor agonist
has_related_synonym: erythropoiesis-stimulating agent
has_related_synonym: erythropoiesis-stimulating agents
in_subset: 3 STAR
imported from: chebi.owl

prostaglandin receptor agonist
type: Class
subclass of: agonist
definition: An agonist that binds to and activates prostaglandin receptors.
id: CHEBI:66900
has_obo_namespace: chebi_ontology
has_related_synonym: prostaglandin receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

CFTR potentiator
type: Class
subclass of: membrane transport modulator
definition: A membrane transport modulator that restores the chloride ion transport ability of defective cystic fibrosis transmembrane conductance regulator (CFTR) genes.
has_related_synonym: CFTR potentiators
id: CHEBI:66902
database_cross_reference: Wikipedia:Cystic_fibrosis_transmembrane_conductance_regulator
has_obo_namespace: chebi_ontology
has_related_synonym: cystic fibrosis transmembrane conductance regulator potentiator
has_related_synonym: cystic fibrosis transmembrane conductance regulator potentiators
in_subset: 3 STAR
imported from: chebi.owl

SMO receptor antagonist
type: Class
subclass of: antagonist
definition: An antagonist that interferes with the action of smoothened (SMO) receptor.
id: CHEBI:66908
has_related_synonym: SMO receptor antagonists
database_cross_reference: Wikipedia:Smoothened
has_obo_namespace: chebi_ontology
has_related_synonym: smoothened antagonist
has_related_synonym: smoothened antagonists
has_related_synonym: smoothened receptor antagonist
has_related_synonym: smoothened receptor antagonists
in_subset: 3 STAR
imported from: chebi.owl

antidyskinesia agent
type: Class
subclass of: drug
definition: Any compound which can be used to treat or alleviate the symptoms of dyskinesia.
id: CHEBI:66956
has_related_synonym: antidyskinesia agents
has_related_synonym: antidyskinesia drug
has_related_synonym: antidyskinesia drugs
has_related_synonym: antidyskinetic agent
has_related_synonym: antidyskinetic agents
has_related_synonym: antidyskinetic drug
has_related_synonym: antidyskinetic drugs
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

nootropic agent
type: Class
subclass of: drug
definition: Any compound that improves mental functions such as cognition, memory, intelligence, motivation, attention, and concentration.
id: CHEBI:66980
database_cross_reference: PMID:22393531
database_cross_reference: PMID:22647316
database_cross_reference: PMID:22742585
database_cross_reference: PMID:22795553
database_cross_reference: PMID:22828638
database_cross_reference: PMID:22837964
database_cross_reference: Wikipedia:Nootropic
has_obo_namespace: chebi_ontology
has_related_synonym: cognitive enhancer
has_related_synonym: cognitive enhancers
has_related_synonym: intelligence enhancer
has_related_synonym: intelligence enhancers
has_related_synonym: memory enhancer
has_related_synonym: memory enhancers
has_related_synonym: neuro enhancer
has_related_synonym: neuro enhancers
has_related_synonym: nootropic
has_related_synonym: nootropic agents
has_related_synonym: nootropic drug
has_related_synonym: nootropic drugs
has_related_synonym: nootropics
has_related_synonym: smart drug
has_related_synonym: smart drugs
in_subset: 3 STAR
imported from: chebi.owl

ophthalmology drug
type: Class
subclass of: drug
definition: Any compound used for the treatment of eye conditions or eye diseases.
id: CHEBI:66981
has_obo_namespace: chebi_ontology
has_related_synonym: ophthalmic
has_related_synonym: ophthalmic agent
has_related_synonym: ophthalmic agents
has_related_synonym: ophthalmics
has_related_synonym: ophthalmological
has_related_synonym: ophthalmologicals
has_related_synonym: ophthalmology agent
has_related_synonym: ophthalmology agents
has_related_synonym: ophthalmology drugs
in_subset: 3 STAR
imported from: chebi.owl

radiation protective agent
type: Class
subclass of: protective agent
definition: Any compound that is able to protect normal cells from the damage caused by radiation therapy.
id: CHEBI:66987
has_obo_namespace: chebi_ontology
has_related_synonym: radiation mitigation agent
has_related_synonym: radiation mitigation agents
has_related_synonym: radiation protective agents
has_related_synonym: radiation protective drug
has_related_synonym: radiation protective drugs
has_related_synonym: radioprotective agent
has_related_synonym: radioprotective agents
has_related_synonym: radioprotector
has_related_synonym: radioprotectors
in_subset: 3 STAR
imported from: chebi.owl

sympatholytic agent
type: Class
subclass of: adrenergic agent
definition: Any compound which inhibits the postganglionic functioning of the sympathetic nervous system (SNS).
id: CHEBI:66991
database_cross_reference: Wikipedia:Sympatholytic
has_obo_namespace: chebi_ontology
has_related_synonym: sympatholytic
has_related_synonym: sympatholytic agents
has_related_synonym: sympatholytic drug
has_related_synonym: sympatholytic drugs
has_related_synonym: sympatholytics
in_subset: 3 STAR
imported from: chebi.owl

tocolytic agent
type: Class
subclass of: reproductive control drug
definition: Any compound used to suppress premature labour and immature birth by suppressing uterine contractions.
id: CHEBI:66993
database_cross_reference: Wikipedia:Tocolytic
has_related_synonym: anti-contraction drug
has_related_synonym: anti-contraction drugs
has_related_synonym: anti-contraction medication
has_related_synonym: anti-contraction medications
has_obo_namespace: chebi_ontology
has_related_synonym: labour repressant
has_related_synonym: labour repressants
has_related_synonym: tocolytic
has_related_synonym: tocolytic agents
has_related_synonym: tocolytic drug
has_related_synonym: tocolytic drugs
has_related_synonym: tocolytics
in_subset: 3 STAR
imported from: chebi.owl

cannabinoid receptor agonist
type: Class
subclass of: agonist
definition: An agonist that binds to and activates cannabinoid receptors.
id: CHEBI:67072
database_cross_reference: Wikipedia:Cannabinoid_receptor
has_related_synonym: cannabinoid receptor agonists
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

anti-inflammatory agent
type: Class
subclass of: application
definition: Any compound that has anti-inflammatory effects.
id: CHEBI:67079
has_related_synonym: anti-inflammatory agents
has_related_synonym: antiinflammatory agent
has_related_synonym: antiinflammatory agents
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

insect sterilant
type: Class
subclass of: chemosterilant
subclass of: insecticide
definition: A chemosterilant intended to sterilize insects.
id: CHEBI:67105
has_obo_namespace: chebi_ontology
has_related_synonym: insect chemosterilant
has_related_synonym: insect chemosterilants
has_related_synonym: insect sterilants
in_subset: 3 STAR
imported from: chebi.owl

ryanodine receptor agonist
type: Class
subclass of: ryanodine receptor modulator
definition: A ryanodine receptor modulator which activates the receptor. Ryanodine receptors (RyRs) act as selective ion channels, modulating the release of calcium. Activating the receptors causes the release of calcium, so depleting internal calcium and ultimately preventing further muscle contraction.
id: CHEBI:67114
database_cross_reference: PMID:30679133
database_cross_reference: PMID:30684528
database_cross_reference: PMID:31840405
database_cross_reference: PMID:8597061
has_related_synonym: RyR activator
has_related_synonym: RyR activators
has_related_synonym: RyR agonist
has_related_synonym: RyR agonists
has_related_synonym: RyRs activator
has_related_synonym: RyRs agonist
database_cross_reference: Wikipedia:Ryanodine_receptor
has_obo_namespace: chebi_ontology
has_related_synonym: ryanodine receptor activator
has_related_synonym: ryanodine receptor activators
in_subset: 3 STAR
imported from: chebi.owl

colorimetric reagent
type: Class
subclass of: reagent
definition: A reagent used in the determination of the concentration of a coloured chemical element or chemical compound in solution.
id: CHEBI:67126
has_obo_namespace: chebi_ontology
has_related_synonym: color reagent
has_related_synonym: color reagents
has_related_synonym: colorimetric reagents
has_related_synonym: colour reagent
has_related_synonym: colour reagents
in_subset: 3 STAR
imported from: chebi.owl

NMR shift reagent
type: Class
subclass of: reagent
id: CHEBI:67137
definition: In NMR spectroscopy a reagent added to a solution to induce chemical shifts and thus simplify complex spectra.
has_related_synonym: NMR shift reagents
has_obo_namespace: chebi_ontology
has_related_synonym: lanthanide shift reagent
has_related_synonym: lanthanide shift reagents
has_related_synonym: nuclear magnetic resonance shift reagent
has_related_synonym: nuclear magnetic resonance shift reagents
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.24.3 (microbial collagenase) inhibitor
type: Class
subclass of: EC 3.4.24.* (metalloendopeptidase) inhibitor
has_related_synonym: Achromobacter iophagus collagenase inhibitor
has_related_synonym: Achromobacter iophagus collagenase inhibitors
definition: An EC 3.4.24.* (metalloendopeptidase) inhibitor which interferes with the action of microbial collagenase (EC 3.4.24.3, also formerly EC 3.4.4.19 and EC 3.4.99.5).
id: CHEBI:67189
has_related_synonym: Clostridium histolyticum collagenase inhibitor
has_related_synonym: Clostridium histolyticum collagenase inhibitors
has_related_synonym: Clostridium histolyticum proteinase A inhibitor
has_related_synonym: Clostridium histolyticum proteinase A inhibitors
has_related_synonym: EC 3.4.24.3 (microbial collagenase) inhibitors
has_related_synonym: EC 3.4.24.3 inhibitor
has_related_synonym: EC 3.4.24.3 inhibitors
has_related_synonym: MMP-1 inhibitor
has_related_synonym: MMP-1 inhibitors
has_related_synonym: MMP-8 inhibitor
has_related_synonym: MMP-8 inhibitors
has_related_synonym: aspergillopeptidase C inhibitor
has_related_synonym: aspergillopeptidase C inhibitors
has_related_synonym: azocollase inhibitor
has_related_synonym: azocollase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: clostridiopeptidase A inhibitor
has_related_synonym: clostridiopeptidase A inhibitors
has_related_synonym: clostridiopeptidase I inhibitor
has_related_synonym: clostridiopeptidase I inhibitors
has_related_synonym: clostridiopeptidase II inhibitor
has_related_synonym: clostridiopeptidase II inhibitors
has_related_synonym: collagen peptidase inhibitor
has_related_synonym: collagen peptidase inhibitors
has_related_synonym: collagen protease inhibitor
has_related_synonym: collagen protease inhibitors
has_related_synonym: collagenase A inhibitor
has_related_synonym: collagenase A inhibitors
has_related_synonym: collagenase I inhibitor
has_related_synonym: collagenase I inhibitors
has_related_synonym: collagenase MMP-1 inhibitor
has_related_synonym: collagenase MMP-1 inhibitors
has_related_synonym: collagenase inhibitor
has_related_synonym: collagenase inhibitors
has_related_synonym: interstitial collagenase inhibitor
has_related_synonym: interstitial collagenase inhibitors
has_related_synonym: kollaza inhibitor
has_related_synonym: kollaza inhibitors
has_related_synonym: matrix metalloproteinase-1 inhibitor
has_related_synonym: matrix metalloproteinase-1 inhibitors
has_related_synonym: matrix metalloproteinase-18 inhibitor
has_related_synonym: matrix metalloproteinase-18 inhibitors
has_related_synonym: matrix metalloproteinase-8 inhibitor
has_related_synonym: matrix metalloproteinase-8 inhibitors
has_related_synonym: metallocollagenase inhibitor
has_related_synonym: metallocollagenase inhibitors
has_related_synonym: metalloproteinase-1 inhibitor
has_related_synonym: metalloproteinase-1 inhibitors
has_related_synonym: microbial collagenase (EC 3.4.24.3) inhibitor
has_related_synonym: microbial collagenase (EC 3.4.24.3) inhibitors
has_related_synonym: microbial collagenase inhibitor
has_related_synonym: microbial collagenase inhibitors
has_related_synonym: nucleolysin inhibitor
has_related_synonym: nucleolysin inhibitors
has_related_synonym: soycollagestin inhibitor
has_related_synonym: soycollagestin inhibitors
in_subset: 3 STAR
imported from: chebi.owl

gap junctional intercellular communication inhibitor
type: Class
subclass of: inhibitor
definition: An inhibitor that interferes with the process of gap junctional intercellular communication.
id: CHEBI:67195
database_cross_reference: Wikipedia:Gap_junction
has_obo_namespace: chebi_ontology
has_related_synonym: gap junctional intercellular communication inhibitors
in_subset: 3 STAR
imported from: chebi.owl

retinoic acid receptor agonist
type: Class
subclass of: agonist
subclass of: retinoic acid receptor modulator
definition: An agonist that selectively binds to and activates a retinoic acid receptor.
id: CHEBI:67198
database_cross_reference: Wikipedia:Retinoic_acid_receptor
has_obo_namespace: chebi_ontology
has_related_synonym: retinoic acid receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

AP-1 antagonist
type: Class
subclass of: antagonist
has_related_synonym: AP-1 antagonists
definition: An antogonist that interferes with the action of activator protein 1 (AP-1).
id: CHEBI:67199
database_cross_reference: Wikipedia:Activator_protein_1
has_related_synonym: activator protein-1 antagonist
has_related_synonym: activator protein-1 antagonists
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

provitamin A
type: Class
subclass of: provitamin
definition: A provitamin that can be converted into vitamin A by enzymes from animal tissues.
id: CHEBI:67200
has_obo_namespace: chebi_ontology
has_related_synonym: provitamin As
in_subset: 3 STAR
imported from: chebi.owl

EC 3.2.1.45 (glucosylceramidase) inhibitor
type: Class
subclass of: EC 3.2.1.* (glycosidase) inhibitor
definition: An EC 3.2.1.* (glycosidase) inhibitor that interferes with the action of glucosylceramidase (EC 3.2.1.45).
id: CHEBI:67230
has_related_synonym: D-glucosyl-N-acylsphingosine glucohydrolase inhibitor
has_related_synonym: D-glucosyl-N-acylsphingosine glucohydrolase inhibitors
has_related_synonym: EC 3.2.1.45 (glucosylceramidase) inhibitors
has_related_synonym: EC 3.2.1.45 inhibitor
has_related_synonym: EC 3.2.1.45 inhibitors
has_related_synonym: GlcCer-beta-glucosidase inhibitor
has_related_synonym: GlcCer-beta-glucosidase inhibitors
database_cross_reference: Wikipedia:Glucosylceramidase
has_related_synonym: acid beta-glucosidase inhibitor
has_related_synonym: acid beta-glucosidase inhibitors
has_related_synonym: acid-beta-glucosidase inhibitor
has_related_synonym: acid-beta-glucosidase inhibitors
has_related_synonym: beta-D-glucocerebrosidase inhibitor
has_related_synonym: beta-D-glucocerebrosidase inhibitors
has_related_synonym: beta-glucosylceramidase inhibitor
has_related_synonym: beta-glucosylceramidase inhibitors
has_related_synonym: ceramide glucosidase inhibitor
has_related_synonym: ceramide glucosidase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: glucocerebrosidase inhibitor
has_related_synonym: glucocerebrosidase inhibitors
has_related_synonym: glucosphingosine glucosylhydrolase inhibitor
has_related_synonym: glucosphingosine glucosylhydrolase inhibitors
has_related_synonym: glucosylceramidase (EC 3.2.1.45) inhibitor
has_related_synonym: glucosylceramidase (EC 3.2.1.45) inhibitors
has_related_synonym: glucosylceramidase inhibitor
has_related_synonym: glucosylceramidase inhibitors
has_related_synonym: glucosylcerebrosidase inhibitor
has_related_synonym: glucosylcerebrosidase inhibitors
has_related_synonym: glucosylsphingosine beta-D-glucosidase inhibitor
has_related_synonym: glucosylsphingosine beta-D-glucosidase inhibitors
has_related_synonym: glucosylsphingosine beta-glucosidase inhibitor
has_related_synonym: glucosylsphingosine beta-glucosidase inhibitors
has_related_synonym: psychosine hydrolase inhibitor
has_related_synonym: psychosine hydrolase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.2.1.48 (sucrose alpha-glucosidase) inhibitor
type: Class
subclass of: EC 3.2.1.* (glycosidase) inhibitor
definition: An EC 3.2.1.* (glycosidase) inhibitor that interferes with the action of sucrose alpha-glucosidase (EC 3.2.1.48).
id: CHEBI:67231
has_related_synonym: EC 3.2.1.48 (sucrose alpha-glucosidase) inhibitors
has_related_synonym: EC 3.2.1.48 inhibitor
has_related_synonym: EC 3.2.1.48 inhibitors
database_cross_reference: Wikipedia:Sucrose_alpha-glucosidase
has_obo_namespace: chebi_ontology
has_related_synonym: intestinal sucrase inhibitor
has_related_synonym: intestinal sucrase inhibitors
has_related_synonym: sucrase (invertase) inhibitor
has_related_synonym: sucrase (invertase) inhibitors
has_related_synonym: sucrase inhibitor
has_related_synonym: sucrase inhibitors
has_related_synonym: sucrase-isomaltase inhibitor
has_related_synonym: sucrase-isomaltase inhibitors
has_related_synonym: sucrose alpha-glucohydrolase inhibitor
has_related_synonym: sucrose alpha-glucohydrolase inhibitors
has_related_synonym: sucrose alpha-glucosidase (EC 3.2.1.48) inhibitor
has_related_synonym: sucrose alpha-glucosidase (EC 3.2.1.48) inhibitors
has_related_synonym: sucrose alpha-glucosidase inhibitor
has_related_synonym: sucrose alpha-glucosidase inhibitors
has_related_synonym: sucrose-alpha-D-glucohydrolase inhibitor
has_related_synonym: sucrose-alpha-D-glucohydrolase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.2.1.10 (oligo-1,6-glucosidase) inhibitor
type: Class
subclass of: EC 3.2.1.* (glycosidase) inhibitor
definition: An EC 3.2.1.* (glycosidase) inhibitor that inhibits the action of sucrose oligo-1,6-glucosidase (EC 3.2.1.10).
id: CHEBI:67232
has_related_synonym: EC 3.2.1.10 (oligo-1,6-glucosidase) inhibitors
has_related_synonym: EC 3.2.1.10 inhibitor
has_related_synonym: EC 3.2.1.10 inhibitors
has_related_synonym: alpha-limit dextrinase inhibitor
has_related_synonym: alpha-limit dextrinase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: dextrin 6-glucanohydrolase inhibitor
has_related_synonym: dextrin 6-glucanohydrolase inhibitors
has_related_synonym: dextrin 6alpha-glucanohydrolase inhibitor
has_related_synonym: dextrin 6alpha-glucanohydrolase inhibitors
has_related_synonym: exo-oligo-1,6-glucosidase inhibitor
has_related_synonym: exo-oligo-1,6-glucosidase inhibitors
has_related_synonym: isomaltase inhibitor
has_related_synonym: isomaltase inhibitors
has_related_synonym: oligo-1,6-glucosidase (EC 3.2.1.10) inhibitor
has_related_synonym: oligo-1,6-glucosidase (EC 3.2.1.10) inhibitors
has_related_synonym: oligo-1,6-glucosidase inhibitor
has_related_synonym: oligo-1,6-glucosidase inhibitors
has_related_synonym: oligosaccharide alpha-1,6-glucohydrolase inhibitor
has_related_synonym: oligosaccharide alpha-1,6-glucohydrolase inhibitors
has_related_synonym: sucrase-isomaltase inhibitor
has_related_synonym: sucrase-isomaltase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.2.1.20 (alpha-glucosidase) inhibitor
type: Class
subclass of: EC 3.2.1.* (glycosidase) inhibitor
definition: An EC 3.2.1.* (glycosidase) inhibitor that interferes with the action of alpha-glucosidase (EC 3.2.1.20).
has_alternative_id: CHEBI:50628
id: CHEBI:67239
has_related_synonym: EC 3.2.1.20 (alpha-glucosidase) inhibitors
has_related_synonym: EC 3.2.1.20 inhibitor
has_related_synonym: EC 3.2.1.20 inhibitors
database_cross_reference: Wikipedia:Alpha-glucosidase_inhibitor
has_related_synonym: alpha-1,4-glucosidase inhibitor
has_related_synonym: alpha-1,4-glucosidase inhibitors
has_related_synonym: alpha-D-glucosidase inhibitor
has_related_synonym: alpha-D-glucosidase inhibitors
has_related_synonym: alpha-glucopyranosidase inhibitor
has_related_synonym: alpha-glucopyranosidase inhibitors
has_related_synonym: alpha-glucosidase (EC 3.2.1.20) inhibitor
has_related_synonym: alpha-glucosidase (EC 3.2.1.20) inhibitors
has_related_synonym: alpha-glucosidase inhibitor
has_related_synonym: alpha-glucosidase inhibitors
has_related_synonym: alpha-glucoside hydrolase inhibitor
has_related_synonym: alpha-glucoside hydrolase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: glucoinvertase inhibitor
has_related_synonym: glucoinvertase inhibitors
has_related_synonym: glucosidoinvertase inhibitor
has_related_synonym: glucosidoinvertase inhibitors
has_related_synonym: glucosidosucrase inhibitor
has_related_synonym: glucosidosucrase inhibitors
has_related_synonym: maltase inhibitor
has_related_synonym: maltase inhibitors
has_related_synonym: maltase-glucoamylase inhibitor
has_related_synonym: maltase-glucoamylase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.5.1.59 (protein geranylgeranyltransferase type I) inhibitor
type: Class
subclass of: EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor
definition: An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of protein geranylgeranyltransferase type I (EC 2.5.1.59).
id: CHEBI:67267
has_related_synonym: EC 2.5.1.59 (protein geranylgeranyltransferase type I) inhibitors
has_related_synonym: EC 2.5.1.59 inhibitor
has_related_synonym: EC 2.5.1.59 inhibitors
has_related_synonym: GGTase I inhibitor
has_related_synonym: GGTase I inhibitors
database_cross_reference: Wikipedia:Protein_geranylgeranyltransferase_type_I
has_obo_namespace: chebi_ontology
has_related_synonym: geranylgeranyl-diphosphate:protein-cysteine geranyltransferase inhibitor
has_related_synonym: geranylgeranyl-diphosphate:protein-cysteine geranyltransferase inhibitors
has_related_synonym: geranylgeranyltransferase type I inhibitor
has_related_synonym: geranylgeranyltransferase type I inhibitors
has_related_synonym: protein geranylgeranyltransferase type I (EC 2.5.1.59) inhibitor
has_related_synonym: protein geranylgeranyltransferase type I (EC 2.5.1.59) inhibitors
has_related_synonym: protein geranylgeranyltransferase type I inhibitor
has_related_synonym: protein geranylgeranyltransferase type I inhibitors
in_subset: 3 STAR
imported from: chebi.owl

HIV-1 integrase inhibitor
type: Class
subclass of: anti-HIV-1 agent
subclass of: EC 2.7.* (P-containing group transferase) inhibitor
definition: An inhibitor of HIV-1 integrase, an enzyme required for the integration of the genetic material of the retrovirus into the DNA of the infected cells.
id: CHEBI:67268
database_cross_reference: Wikipedia:Discovery_and_development_of_integrase_inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

metformin
type: Class
subclass of: molecular entity
charge: 0
has_related_synonym: 1,1-dimethylbiguanide
monoisotopicmass: 129.10145
mass: 129.167
definition: A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
formula: C4H11N5
database_cross_reference: CAS:657-24-9
id: CHEBI:6801
smiles: CN(C)C(=N)NC(N)=N
database_cross_reference: DrugBank:DB00331
database_cross_reference: Drug_Central:1725
database_cross_reference: FooDB:FDB022739
database_cross_reference: HMDB:HMDB0001921
inchi: InChI=1S/C4H11N5/c1-9(2)4(7)8-3(5)6/h1-2H3,(H5,5,6,7,8)
database_cross_reference: KEGG:C07151
database_cross_reference: KEGG:D04966
has_related_synonym: LA 6023
has_related_synonym: LA-6023
database_cross_reference: LINCS:LSM-4730
has_related_synonym: N(1),N(1)-dimethylbiguanide
has_related_synonym: N,N-dimethylbiguanide
has_related_synonym: N,N-dimethyldiguanide
has_related_synonym: N,N-dimethylguanylguanidine
has_related_synonym: N,N-dimethylimidodicarbonimidic diamide
has_exact_synonym: N,N-dimethyltriimidodicarbonic diamide
database_cross_reference: PDBeChem:MF8
database_cross_reference: PMID:10900588
database_cross_reference: PMID:10983737
database_cross_reference: PMID:10999803
database_cross_reference: PMID:11012555
database_cross_reference: PMID:11126815
database_cross_reference: PMID:11192132
database_cross_reference: PMID:11257323
database_cross_reference: PMID:11544610
database_cross_reference: PMID:11772907
database_cross_reference: PMID:12086935
database_cross_reference: PMID:12406042
database_cross_reference: PMID:12436333
database_cross_reference: PMID:12630933
database_cross_reference: PMID:12909816
database_cross_reference: PMID:15261814
database_cross_reference: PMID:15606381
database_cross_reference: PMID:15650645
database_cross_reference: PMID:15717887
database_cross_reference: PMID:15932841
database_cross_reference: PMID:16294070
database_cross_reference: PMID:16520442
database_cross_reference: PMID:16941277
database_cross_reference: PMID:17062558
database_cross_reference: PMID:18212742
database_cross_reference: PMID:18608522
database_cross_reference: PMID:23077661
database_cross_reference: PMID:23540700
database_cross_reference: PMID:24428821
database_cross_reference: PMID:28919040
database_cross_reference: PMID:31208831
database_cross_reference: PMID:33191721
database_cross_reference: Reaxys:606492
database_cross_reference: Wikipedia:Metformin
inchikey: XZWYZXLIPXDOLR-UHFFFAOYSA-N
has_obo_namespace: chebi_ontology
has_related_synonym: dimethylbiguanide
has_related_synonym: dimethyldiguanide
has_related_synonym: metformin
has_related_synonym: metformina
has_related_synonym: metformine
has_related_synonym: metforminum
in_subset: 3 STAR
imported from: chebi.owl

mTOR inhibitor
type: Class
subclass of: protein kinase inhibitor
definition: A protein kinase inhibitor of the mammalian target of rapamycin (mTOR), a protein that regulates cell growth, cell proliferation, cell motility, cell survival, protein synthesis and transcription. mTOR inhibitors are used to prevent transplant rejection and in treatment of cancer.
id: CHEBI:68481
database_cross_reference: Wikipedia:MTOR_inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: mTOR inhibitors
has_related_synonym: mammalian target of rapamycin inhibitor
has_related_synonym: mammalian target of rapamycin inhibitors
in_subset: 3 STAR
imported from: chebi.owl

apoptosis inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
definition: Any substance that inhibits the process of apoptosis (programmed cell death) in multi-celled organisms.
id: CHEBI:68494
has_related_synonym: Type I cell-death inhibitor
has_related_synonym: Type I cell-death inhibitors
has_related_synonym: Type I programmed cell-death inhibitor
has_related_synonym: Type I programmed cell-death inhibitors
has_related_synonym: apoptosis inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

apoptosis inducer
type: Class
subclass of: biochemical role
definition: Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
id: CHEBI:68495
has_related_synonym: Type I cell-death inducer
has_related_synonym: Type I cell-death inducers
has_related_synonym: Type I programmed cell-death inducer
has_related_synonym: Type I programmed cell-death inducers
has_related_synonym: apoptosis inducers
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

glutathione depleting agent
type: Class
subclass of: biological role
definition: A compound which causes a reduction in the levels of glutathione in cells.
id: CHEBI:68509
has_obo_namespace: chebi_ontology
has_related_synonym: glutathione depleting agents
has_related_synonym: glutathione depletion agent
has_related_synonym: glutathione depletion agents
has_related_synonym: glutathione depletor
has_related_synonym: glutathione depletors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.3.98.1 [dihydroorotate oxidase (fumarate)] inhibitor
type: Class
subclass of: EC 1.3.98.* (oxidoreductase acting on donor CH-CH group, with other, known, acceptors) inhibitor
has_related_synonym: (S)-dihydroorotate:fumarate oxidoreductase inhibitor
has_related_synonym: (S)-dihydroorotate:fumarate oxidoreductase inhibitors
definition: An EC 1.3.98.* (oxidoreductase acting on CH-CH group of donors, with other, known, acceptors) inhibitor that interferes with the action of dihydroorotate oxidase (fumarate), EC 1.3.98.1 (formerly EC 1.3.3.1).
id: CHEBI:68542
has_related_synonym: DHODH inhibitor
has_related_synonym: DHODH inhibitors
has_related_synonym: EC 1.3.3.1 inhibitor
has_related_synonym: EC 1.3.3.1 inhibitors
has_related_synonym: EC 1.3.98.1 (dihydroorotate oxidase (fumarate)) inhibitor
has_related_synonym: EC 1.3.98.1 (dihydroorotate oxidase (fumarate)) inhibitors
has_related_synonym: EC 1.3.98.1 [dihydroorotate oxidase (fumarate)] inhibitors
has_related_synonym: EC 1.3.98.1 inhibitor
has_related_synonym: EC 1.3.98.1 inhibitors
database_cross_reference: Wikipedia:Dihydroorotate_dehydrogenase
has_obo_namespace: chebi_ontology
has_related_synonym: dihydroorotate dehydrogenase inhibitor
has_related_synonym: dihydroorotate dehydrogenase inhibitors
has_related_synonym: dihydroorotate oxidase (fumarate) (EC 1.3.98.1) inhibitor
has_related_synonym: dihydroorotate oxidase (fumarate) (EC 1.3.98.1) inhibitors
has_related_synonym: dihydroorotate oxidase (fumarate) inhibitor
has_related_synonym: dihydroorotate oxidase (fumarate) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

pyrimidine synthesis inhibitor
type: Class
subclass of: pathway inhibitor
definition: A pathway inhibitor that inhibits the synthesis of pyrimidine.
id: CHEBI:68543
database_cross_reference: Wikipedia:Pyrimidine_metabolism
has_obo_namespace: chebi_ontology
has_related_synonym: pyrimidine synthesis inhibitors
in_subset: 3 STAR
imported from: chebi.owl

guanylate cyclase 2C agonist
type: Class
subclass of: agonist
definition: An agonist that selectively binds to and activates guanylate cyclase 2C receptors.
id: CHEBI:68553
has_related_synonym: GC-C agonist
has_related_synonym: GC-C agonists
has_obo_namespace: chebi_ontology
has_related_synonym: guanylate cyclase 2C agonists
in_subset: 3 STAR
imported from: chebi.owl

bradykinin receptor antagonist
type: Class
subclass of: antagonist
definition: An antagonist at the bradykinin receptor.
id: CHEBI:68557
has_related_synonym: bradykinin receptor antagonists
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

P2Y12 receptor antagonist
type: Class
subclass of: purinergic receptor P2 antagonist
has_related_synonym: ADP receptor subtype P2Y12 antagonist
has_related_synonym: ADP receptor subtype P2Y12 antagonists
definition: An antagonist at the P2Y12 receptor
id: CHEBI:68563
has_related_synonym: P2Y12 receptor antagonists
database_cross_reference: Wikipedia:P2Y12
has_obo_namespace: chebi_ontology
has_related_synonym: purinergic receptor subtype P2Y12 antagonist
has_related_synonym: purinergic receptor subtype P2Y12 antagonists
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.21.6 (coagulation factor Xa) inhibitor
type: Class
subclass of: EC 3.4.21.* (serine endopeptidase) inhibitor
definition: An EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of coagulation factor Xa (EC 3.4.21.6).
id: CHEBI:68581
has_related_synonym: EC 3.4.21.6 (coagulation factor Xa) inhibitors
has_related_synonym: EC 3.4.21.6 inhibitor
has_related_synonym: EC 3.4.21.6 inhibitors
has_related_synonym: Stuart factor inhibitor
has_related_synonym: Stuart factor inhibitors
database_cross_reference: Wikipedia:Factor_Xa_inhibitor
has_related_synonym: activated Stuart-Prower factor inhibitor
has_related_synonym: activated Stuart-Prower factor inhibitors
has_related_synonym: activated blood-coagulation factor X inhibitor
has_related_synonym: activated blood-coagulation factor X inhibitors
has_related_synonym: activated factor X inhibitor
has_related_synonym: activated factor X inhibitors
has_related_synonym: autoprothrombin C inhibitor
has_related_synonym: autoprothrombin C inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: coagulation factor Xa (EC 3.4.21.6) inhibitor
has_related_synonym: coagulation factor Xa (EC 3.4.21.6) inhibitors
has_related_synonym: coagulation factor Xa inhibitor
has_related_synonym: coagulation factor Xa inhibitors
has_related_synonym: factor Xa inhibitor
has_related_synonym: factor Xa inhibitors
has_related_synonym: plasma thromboplastin inhibitor
has_related_synonym: plasma thromboplastin inhibitors
has_related_synonym: prothrombase inhibitor
has_related_synonym: prothrombase inhibitors
has_related_synonym: prothrombinase inhibitor
has_related_synonym: prothrombinase inhibitors
has_related_synonym: thrombokinase inhibitor
has_related_synonym: thrombokinase inhibitors
has_related_synonym: thromboplastin inhibitor
has_related_synonym: thromboplastin inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor
type: Class
subclass of: EC 3.4.14.* (dipeptidyl- and tripeptidyl-peptidases) inhibitor
definition: An EC 3.4.14.* (dipeptidyl- and tripeptidyl-peptidases) inhibitor that specifically inhibits dipeptidyl peptidase-4 (EC 3.4.14.5).
id: CHEBI:68612
has_alternative_id: CHEBI:76927
has_related_synonym: DPP IV/CD26 inhibitor
has_related_synonym: DPP IV/CD26 inhibitors
has_related_synonym: DPP-4 inhibitor
has_related_synonym: DPP-4 inhibitors
has_related_synonym: EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitors
has_related_synonym: EC 3.4.14.5 inhibitor
has_related_synonym: EC 3.4.14.5 inhibitors
has_related_synonym: Gly-Pro naphthylamidase inhibitor
has_related_synonym: Gly-Pro naphthylamidase inhibitors
has_related_synonym: T cell triggering molecule Tp103 inhibitor
has_related_synonym: T cell triggering molecule Tp103 inhibitors
database_cross_reference: Wikipedia:Dipeptidyl_peptidase-4_inhibitor
has_related_synonym: X-PDAP inhibitor
has_related_synonym: X-PDAP inhibitors
has_related_synonym: X-prolyl dipeptidyl aminopeptidase inhibitor
has_related_synonym: X-prolyl dipeptidyl aminopeptidase inhibitors
has_related_synonym: Xaa-Pro-dipeptidyl-aminopeptidase inhibitor
has_related_synonym: Xaa-Pro-dipeptidyl-aminopeptidase inhibitors
has_related_synonym: amino acyl-prolyl dipeptidyl aminopeptidase inhibitor
has_related_synonym: amino acyl-prolyl dipeptidyl aminopeptidase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: dipeptidyl aminopeptidase IV inhibitor
has_related_synonym: dipeptidyl aminopeptidase IV inhibitors
has_related_synonym: dipeptidyl peptidase IV inhibitor
has_related_synonym: dipeptidyl peptidase IV inhibitors
has_related_synonym: dipeptidyl peptidase-4 inhibitors
has_related_synonym: dipeptidyl-aminopeptidase IV inhibitor
has_related_synonym: dipeptidyl-aminopeptidase IV inhibitors
has_related_synonym: dipeptidyl-peptidase IV (EC 3.4.14.5) inhibitor
has_related_synonym: dipeptidyl-peptidase IV (EC 3.4.14.5) inhibitors
has_related_synonym: dipeptidyl-peptidase IV inhibitor
has_related_synonym: dipeptidyl-peptidase IV inhibitors
has_related_synonym: dipeptidyl-peptide hydrolase inhibitor
has_related_synonym: dipeptidyl-peptide hydrolase inhibitors
has_related_synonym: glycoprotein GP110 inhibitor
has_related_synonym: glycoprotein GP110 inhibitors
has_related_synonym: glycylproline aminopeptidase inhibitor
has_related_synonym: glycylproline aminopeptidase inhibitors
has_related_synonym: glycylprolyl aminopeptidase inhibitor
has_related_synonym: glycylprolyl aminopeptidase inhibitors
has_related_synonym: glycylprolyl dipeptidylaminopeptidase inhibitor
has_related_synonym: glycylprolyl dipeptidylaminopeptidase inhibitors
has_related_synonym: leukocyte antigen CD26 inhibitor
has_related_synonym: leukocyte antigen CD26 inhibitors
has_related_synonym: lymphocyte antigen CD26 inhibitor
has_related_synonym: lymphocyte antigen CD26 inhibitors
has_related_synonym: pep X inhibitor
has_related_synonym: pep X inhibitors
has_related_synonym: postproline dipeptidyl aminopeptidase IV inhibitor
has_related_synonym: postproline dipeptidyl aminopeptidase IV inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.14.99.9 (steroid 17alpha-monooxygenase) inhibitor
type: Class
subclass of: EC 1.14.99.* (miscellaneous oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor
has_related_synonym: 17-alpha-hydroxylase/C17,20-lyase inhibitor
has_related_synonym: 17-alpha-hydroxylase/C17,20-lyase inhibitors
has_related_synonym: 17alpha-hydroxylase-C17,20 lyase inhibitor
has_related_synonym: 17alpha-hydroxylase-C17,20 lyase inhibitors
definition: An EC 1.14.99.* (miscellaneous oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of cytochrome P450 17-alpha-hydroxylase/C17,20-lyase (EC 1.14.99.9).
id: CHEBI:68640
has_related_synonym: CYP17 inhibitor
has_related_synonym: CYP17 inhibitors
has_related_synonym: CYP17A1 inhibitor
has_related_synonym: CYP17A1 inhibitors
has_related_synonym: EC 1.14.99.9 (steroid 17alpha-monooxygenase) inhibitors
has_related_synonym: EC 1.14.99.9 inhibitor
has_related_synonym: EC 1.14.99.9 inhibitors
database_cross_reference: Wikipedia:CYP17A1
has_obo_namespace: chebi_ontology
has_related_synonym: cytochrome P-45017alpha inhibitor
has_related_synonym: cytochrome P-45017alpha inhibitors
has_related_synonym: cytochrome P450 (P-45017alpha,lyase) inhibitor
has_related_synonym: cytochrome P450 (P-45017alpha,lyase) inhibitors
has_related_synonym: cytochrome P450 17-alpha-hydroxylase/C17,20-lyase inhibitor
has_related_synonym: cytochrome P450 17-alpha-hydroxylase/C17,20-lyase inhibitors
has_related_synonym: cytochrome p450 XVIIA1 inhibitor
has_related_synonym: cytochrome p450 XVIIA1 inhibitors
has_related_synonym: steroid 17alpha-hydroxylase inhibitor
has_related_synonym: steroid 17alpha-hydroxylase inhibitors
has_related_synonym: steroid 17alpha-monooxygenase (EC 1.14.99.9) inhibitor
has_related_synonym: steroid 17alpha-monooxygenase (EC 1.14.99.9) inhibitors
has_related_synonym: steroid 17alpha-monooxygenase inhibitor
has_related_synonym: steroid 17alpha-monooxygenase inhibitors
has_related_synonym: steroid 17alphahydroxylase/17,20 lyase inhibitor
has_related_synonym: steroid 17alphahydroxylase/17,20 lyase inhibitors
has_related_synonym: steroid,NADPH--hemoprotein reductase:oxygen oxidoreductase (17alpha-hydroxylating) inhibitor
has_related_synonym: steroid,NADPH--hemoprotein reductase:oxygen oxidoreductase (17alpha-hydroxylating) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

phosphodiesterase IV inhibitor
type: Class
subclass of: EC 3.1.4.53 (3',5'-cyclic-AMP phosphodiesterase) inhibitor
definition: An EC 3.1.4.53 (3',5'-cyclic-AMP phosphodiesterase) inhibitor that specifically blocks the action of phosphodiesterase IV.
id: CHEBI:68844
has_related_synonym: PDE4 inhibitor
has_related_synonym: PDE4 inhibitors
database_cross_reference: Wikipedia:Phosphodiesterase-4_inhibitor
has_obo_namespace: chebi_ontology
has_related_synonym: phosphodiesterase 4 inhibitor
has_related_synonym: phosphodiesterase 4 inhibitors
has_related_synonym: phosphodiesterase IV inhibitors
has_related_synonym: type 4 phosphodiesterase inhibitor
has_related_synonym: type 4 phosphodiesterase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

midazolam
type: Class
subclass of: molecular entity
charge: 0
monoisotopicmass: 325.07820
mass: 325.768
has_exact_synonym: 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine
definition: An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
has_related_synonym: Buccolam
formula: C18H13ClFN3
database_cross_reference: CAS:59467-70-8
id: CHEBI:6931
inchikey: DDLIGBOFAVUZHB-UHFFFAOYSA-N
has_related_synonym: Dormicum
database_cross_reference: DrugBank:DB00683
database_cross_reference: Drug_Central:1802
database_cross_reference: HMDB:HMDB0014821
inchi: InChI=1S/C18H13ClFN3/c1-11-21-9-13-10-22-18(14-4-2-3-5-16(14)20)15-8-12(19)6-7-17(15)23(11)13/h2-9H,10H2,1H3
database_cross_reference: KEGG:C07524
database_cross_reference: KEGG:D00550
database_cross_reference: LINCS:LSM-5200
database_cross_reference: MetaCyc:CPD-20500
database_cross_reference: PDBeChem:08J
database_cross_reference: PMID:1832310
database_cross_reference: PMID:26032507
database_cross_reference: PMID:28706559
database_cross_reference: PMID:29516686
database_cross_reference: PMID:30076807
database_cross_reference: PMID:30113394
database_cross_reference: PMID:30157038
database_cross_reference: Reaxys:625572
database_cross_reference: Wikipedia:Midazolam
has_obo_namespace: chebi_ontology
has_related_synonym: mezolam
has_related_synonym: midazolam
has_related_synonym: midazolamum
in_subset: 3 STAR
imported from: chebi.owl

progesterone receptor agonist
type: Class
subclass of: hormone agonist
definition: A hormone agonist that binds to and activates progesterone receptors.
id: CHEBI:70709
has_related_synonym: PR agonist
has_related_synonym: PR agonists
has_obo_namespace: chebi_ontology
has_related_synonym: progesterone receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor
type: Class
subclass of: EC 6.4.1.* (carboxylase) inhibitor
has_related_synonym: ACC inhibitor
has_related_synonym: ACC inhibitors
has_related_synonym: ACCase inhibitor
has_related_synonym: ACCase inhibitors
definition: An EC 6.4.1.* (C-C bond-forming ligase) inhibitor that interferes with the action of acetyl-CoA carboxylase (EC 6.4.1.2).
id: CHEBI:70722
has_related_synonym: EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitors
has_related_synonym: EC 6.4.1.2 inhibitor
has_related_synonym: EC 6.4.1.2 inhibitors
database_cross_reference: PMID:19552511
database_cross_reference: PMID:22560583
database_cross_reference: PMID:22677317
database_cross_reference: Patent:US2009270435
database_cross_reference: Wikipedia:Acetyl_CoA_carboxylase
has_related_synonym: acetyl coenzyme A carboxylase inhibitor
has_related_synonym: acetyl coenzyme A carboxylase inhibitors
has_related_synonym: acetyl-CoA carboxylase (EC 6.4.1.2) inhibitor
has_related_synonym: acetyl-CoA carboxylase (EC 6.4.1.2) inhibitors
has_related_synonym: acetyl-CoA carboxylase inhibitor
has_related_synonym: acetyl-CoA carboxylase inhibitors
has_related_synonym: acetyl-CoA:carbon-dioxide ligase (ADP-forming) inhibitor
has_related_synonym: acetyl-CoA:carbon-dioxide ligase (ADP-forming) inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

cell dedifferentiation agent
type: Class
subclass of: biochemical role
definition: Any compound which induces a partially or terminally differentiated cell to revert to an earlier developmental stage.
id: CHEBI:70724
has_related_synonym: cell dedifferentiation agents
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

adenosine A3 receptor antagonist
type: Class
subclass of: adenosine receptor antagonist
definition: An antagonist at the A3 receptor.
id: CHEBI:70725
database_cross_reference: Wikipedia:Adenosine_A3_receptor
has_related_synonym: adenosine A3 receptor antagonistS
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

topoisomerase inhibitor
type: Class
subclass of: EC 5.99.1.* (miscellaneous isomerase) inhibitor
definition: An EC 5.99.1.* (miscellaneous isomerase) inhibitor that interferes with the action of any of the topoisomerases (enzymes that regulate the overwinding or underwinding of DNA).
id: CHEBI:70727
database_cross_reference: Wikipedia:Topoisomerase
has_obo_namespace: chebi_ontology
has_related_synonym: topoisomerase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

actin polymerisation inhibitor
type: Class
subclass of: inhibitor
definition: Any substance that inhibits the polymerisation of the protein actin.
id: CHEBI:70728
has_related_synonym: actin polymerisation inhibitors
has_related_synonym: actin polymerization inhibitor
has_related_synonym: actin polymerization inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of actin polymerization
has_related_synonym: inhibitors of actin polymerization
in_subset: 3 STAR
imported from: chebi.owl

Aurora kinase inhibitor
type: Class
subclass of: protein kinase inhibitor
definition: Any protein kinase inhibitor that inhibits the action of an Aurora kinase (a group of serine/threonine kinases that are essential for cell proliferation).
has_related_synonym: Aurora kinase inhibitors
id: CHEBI:70770
database_cross_reference: PMID:19369091
database_cross_reference: PMID:21147253
database_cross_reference: PMID:22350019
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

capsaicin receptor antagonist
type: Class
subclass of: antagonist
definition: Any substance which blocks the painful sensation of heat caused by capsaicin acting on the TRPV1 ion channel.
id: CHEBI:70774
has_related_synonym: TRPV1 antagonist
has_related_synonym: TRPV1 antagonists
has_related_synonym: TrpV1 antagonist
has_related_synonym: TrpV1 antagonists
database_cross_reference: Wikipedia:Discovery_and_development_of_TRPV1_antagonists
has_related_synonym: capsaicin antagonist
has_related_synonym: capsaicin antagonists
has_related_synonym: capsaicin receptor antagonists
has_obo_namespace: chebi_ontology
has_related_synonym: transient receptor potential cation channel subfamily V member 1 antagonist
has_related_synonym: transient receptor potential cation channel subfamily V member 1 antagonists
has_related_synonym: vanilloid receptor 1 antagonist
has_related_synonym: vanilloid receptor 1 antagonists
in_subset: 3 STAR
imported from: chebi.owl

PPAR modulator
type: Class
subclass of: pharmacological role
definition: Any compound which acts on the peroxisome proliferator-activated receptor.
id: CHEBI:70781
database_cross_reference: PMID:18566691
database_cross_reference: PMID:19746174
has_related_synonym: PPAR modulators
database_cross_reference: Wikipedia:Peroxisome_proliferator-activated_receptor
has_obo_namespace: chebi_ontology
has_related_synonym: peroxisome proliferator-activated receptor modulator
has_related_synonym: peroxisome proliferator-activated receptor modulators
in_subset: 3 STAR
imported from: chebi.owl

PPARalpha agonist
type: Class
subclass of: agonist
subclass of: PPAR modulator
definition: A PPAR modulator which activates the peroxisome proliferator-activated receptor-alpha.
id: CHEBI:70782
has_related_synonym: PPAR-alpha agonist
has_related_synonym: PPAR-alpha agonists
has_exact_synonym: PPARalpha agonist
has_related_synonym: PPARalpha agonists
database_cross_reference: Wikipedia:Peroxisome_proliferator-activated_receptor_alpha
has_obo_namespace: chebi_ontology
has_related_synonym: peroxisome proliferator-activated receptor-alpha agonist
has_related_synonym: peroxisome proliferator-activated receptor-alpha agonists
in_subset: 3 STAR
imported from: chebi.owl

EC 1.2.1.12 [glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)] inhibitor
type: Class
subclass of: EC 1.2.1.* (oxidoreductase acting on donor aldehyde/oxo group with NAD(+) or NADP(+) as acceptor) inhibitor
has_related_synonym: 3-phosphoglyceraldehyde dehydrogenase inhibitor
has_related_synonym: 3-phosphoglyceraldehyde dehydrogenase inhibitors
definition: An EC 1.2.1.* (oxidoreductase acting on donor aldehyde/oxo group with NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12).
id: CHEBI:70817
has_related_synonym: D-glyceraldehyde-3-phosphate:NAD(+) oxidoreductase (phosphorylating) inhibitor
has_related_synonym: D-glyceraldehyde-3-phosphate:NAD(+) oxidoreductase (phosphorylating) inhibitors
has_related_synonym: EC 1.2.1.12 (glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)) inhibitor
has_related_synonym: EC 1.2.1.12 (glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)) inhibitors
has_related_synonym: EC 1.2.1.12 [glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)] inhibitors
has_related_synonym: EC 1.2.1.12 inhibitor
has_related_synonym: EC 1.2.1.12 inhibitors
has_related_synonym: GAPDH inhibitor
has_related_synonym: GAPDH inhibitors
has_related_synonym: NAD-dependent glyceraldehyde phosphate dehydrogenase inhibitor
has_related_synonym: NAD-dependent glyceraldehyde phosphate dehydrogenase inhibitors
has_related_synonym: NADH-glyceraldehyde phosphate dehydrogenase inhibitor
has_related_synonym: NADH-glyceraldehyde phosphate dehydrogenase inhibitors
database_cross_reference: Wikipedia:Glyceraldehyde-3-phosphate_dehydrogenase
has_obo_namespace: chebi_ontology
has_related_synonym: dehydrogenase, glyceraldehyde phosphate inhibitor
has_related_synonym: dehydrogenase, glyceraldehyde phosphate inhibitors
has_related_synonym: glyceraldehyde phosphate dehydrogenase (NAD) inhibitor
has_related_synonym: glyceraldehyde phosphate dehydrogenase (NAD) inhibitors
has_related_synonym: glyceraldehyde-3-P-dehydrogenase inhibitor
has_related_synonym: glyceraldehyde-3-P-dehydrogenase inhibitors
has_related_synonym: glyceraldehyde-3-phosphate dehydrogenase (NAD) inhibitor
has_related_synonym: glyceraldehyde-3-phosphate dehydrogenase (NAD) inhibitors
has_related_synonym: glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) (EC 1.2.1.12) inhibitor
has_related_synonym: glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) (EC 1.2.1.12) inhibitors
has_related_synonym: glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) inhibitor
has_related_synonym: glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) inhibitors
has_related_synonym: glyceraldehyde-3-phosphate dehydrogenase inhibitor
has_related_synonym: glyceraldehyde-3-phosphate dehydrogenase inhibitors
has_related_synonym: phosphoglyceraldehyde dehydrogenase inhibitor
has_related_synonym: phosphoglyceraldehyde dehydrogenase inhibitors
has_related_synonym: triosephosphate dehydrogenase inhibitor
has_related_synonym: triosephosphate dehydrogenase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

cathepsin L (EC 3.4.22.15) inhibitor
type: Class
subclass of: cysteine protease inhibitor
subclass of: EC 3.4.22.* (cysteine endopeptidase) inhibitor
has_related_synonym: Aldrichina grahami cysteine proteinase inhibitor
has_related_synonym: Aldrichina grahami cysteine proteinase inhibitors
definition: An EC 3.4.22.* (cysteine endopeptidase) inhibitor which interferes with the action of cathepsin L (EC 3.4.22.15).
id: CHEBI:70821
has_related_synonym: EC 3.4.22.15 inhibitor
has_related_synonym: EC 3.4.22.15 inhibitors
database_cross_reference: Wikipedia:Cathepsin_L
has_exact_synonym: cathepsin L (EC 3.4.22.15) inhibitor
has_related_synonym: cathepsin L (EC 3.4.22.15) inhibitors
has_related_synonym: cathepsin L inhibitor
has_related_synonym: cathepsin L inhibitors
has_related_synonym: cathepsin L1 inhibitor
has_related_synonym: cathepsin L1 inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.22.2 (papain) inhibitor
type: Class
subclass of: cysteine protease inhibitor
subclass of: EC 3.4.22.* (cysteine endopeptidase) inhibitor
definition: A cysteine protease inhibitor which inhibits papain (EC 3.4.22.2).
id: CHEBI:70822
has_exact_synonym: EC 3.4.22.2 (papain) inhibitor
has_related_synonym: EC 3.4.22.2 inhibitor
has_related_synonym: EC 3.4.22.2 inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: papain (EC 3.4.22.2) inhibitor
has_related_synonym: papain (EC 3.4.22.2) inhibitors
has_related_synonym: papain inhibitor
has_related_synonym: papain inhibitors
has_related_synonym: papaine inhibitor
has_related_synonym: papaine inhibitors
has_related_synonym: papaya peptidase I inhibitor
has_related_synonym: papaya peptidase I inhibitors
has_related_synonym: papayotin inhibitor
has_related_synonym: papayotin inhibitors
has_related_synonym: summetrin inhibitor
has_related_synonym: summetrin inhibitors
has_related_synonym: velardon inhibitor
has_related_synonym: velardon inhibitors
in_subset: 3 STAR
imported from: chebi.owl

antileishmanial agent
type: Class
subclass of: antiprotozoal drug
definition: An antiprotozoal drug used to treat or prevent infections caused by protozoan parasites that belong to the genus Leishmania.
id: CHEBI:70868
has_related_synonym: antileishmanial agents
has_related_synonym: antileishmanial drug
has_related_synonym: antileishmanial drugs
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

reactive oxygen species generator
type: Class
subclass of: chemical role
definition: Any entity used to generate reactive oxygen species.
id: CHEBI:70982
has_related_synonym: ROS generator
has_related_synonym: ROS generators
has_obo_namespace: chebi_ontology
has_related_synonym: reactive oxygen species generators
in_subset: 3 STAR
imported from: chebi.owl

G-protein-coupled receptor agonist
type: Class
subclass of: agonist
definition: An agonist that binds to and activates G-protein-coupled receptors
id: CHEBI:70998
has_related_synonym: G-protein-coupled receptor agonists
has_related_synonym: GPCR agonist
has_related_synonym: GPCR agonists
database_cross_reference: Wikipedia:G_protein-coupled_receptor
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

AMPA receptor antagonist
type: Class
subclass of: antagonist
has_related_synonym: AMPA receptor antagonists
definition: An antagonist at the AMPA receptor.
id: CHEBI:71014
database_cross_reference: Wikipedia:AMPA_receptor
has_related_synonym: alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonist
has_related_synonym: alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonists
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

progesterone receptor modulator
type: Class
subclass of: hormone receptor modulator
definition: A hormone receptor modulator that acts as a complete or partial agonist or as an antagonist at the progesterone receptor.
id: CHEBI:71027
database_cross_reference: Wikipedia:Selective_progesterone_receptor_modulator
has_obo_namespace: chebi_ontology
has_related_synonym: progesterone receptor modulators
in_subset: 3 STAR
imported from: chebi.owl

orphan drug
type: Class
subclass of: drug
definition: Any drug that has been developed specifically for treatment of a rare medical condition, the condition itself being known as an orphan disease.
id: CHEBI:71031
database_cross_reference: PMID:20036435
database_cross_reference: PMID:20800761
database_cross_reference: PMID:21180460
database_cross_reference: PMID:21682893
database_cross_reference: PMID:21947805
database_cross_reference: PMID:22363762
database_cross_reference: PMID:22366309
database_cross_reference: PMID:22371464
database_cross_reference: PMID:22731105
database_cross_reference: PMID:22739138
database_cross_reference: PMID:22747423
database_cross_reference: PMID:22814659
database_cross_reference: PMID:22814660
database_cross_reference: PMID:22973866
database_cross_reference: PMID:22981668
database_cross_reference: PMID:22989856
database_cross_reference: PMID:23013790
database_cross_reference: PMID:23090701
database_cross_reference: PMID:23109143
database_cross_reference: PMID:23129684
database_cross_reference: Wikipedia:Orphan_drug
has_obo_namespace: chebi_ontology
has_related_synonym: orphan drugs
in_subset: 3 STAR
imported from: chebi.owl

carbamylphosphate synthetase I activator
type: Class
subclass of: enzyme activator
definition: Any compound that binds and activates the enzyme carbamylphosphate synthetase I.
id: CHEBI:71033
database_cross_reference: Wikipedia:Carbamoyl_phosphate_synthetase_I
has_related_synonym: carbamylphosphate synthetase I activators
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

HIV-1 maturation inhibitor
type: Class
subclass of: inhibitor
subclass of: anti-HIV-1 agent
definition: A compound that blocks the processing of the Gag precursor protein in HIV-1 by the viral protease enzyme, leading to the formation of noninfectious, immature virus particles that are incapable of infecting other cells.
id: CHEBI:71168
has_related_synonym: HIV-1 maturation inhibitors
database_cross_reference: Wikipedia:Maturation_inhibitor
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

H1-receptor agonist
type: Class
subclass of: histamine agonist
definition: A histamine agonist that binds to and activates H1-receptors.
id: CHEBI:71173
has_related_synonym: H1-receptor agonists
database_cross_reference: Wikipedia:Histamine_H1_receptor
has_obo_namespace: chebi_ontology
has_related_synonym: histamine H1-receptor agonist
has_related_synonym: histamine H1-receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

EC 2.1.1.4 (acetylserotonin O-methyltransferase) inhibitor
type: Class
subclass of: EC 2.1.1.* (methyltransferases) inhibitor
has_related_synonym: ASMT inhibitor
has_related_synonym: ASMT inhibitors
definition: An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of N-acetylserotonin methyltransferase (EC 2.1.1.4).
id: CHEBI:71178
has_related_synonym: EC 2.1.1.4 (acetylserotonin O-methyltransferase) inhibitors
has_related_synonym: EC 2.1.1.4 inhibitor
has_related_synonym: EC 2.1.1.4 inhibitors
has_related_synonym: N-acetylserotonin O-methyltransferase inhibitor
has_related_synonym: N-acetylserotonin O-methyltransferase inhibitors
has_related_synonym: N-acetylserotonin methyltransferase inhibitor
has_related_synonym: N-acetylserotonin methyltransferase inhibitors
has_related_synonym: S-adenosyl-L-methionine:N-acetylserotonin O-methyltransferase inhibitor
has_related_synonym: S-adenosyl-L-methionine:N-acetylserotonin O-methyltransferase inhibitors
database_cross_reference: Wikipedia:Acetylserotonin_O-methyltransferase
has_related_synonym: acetylserotonin O-methyltransferase (EC 2.1.1.4) inhibitor
has_related_synonym: acetylserotonin O-methyltransferase (EC 2.1.1.4) inhibitors
has_related_synonym: acetylserotonin O-methyltransferase inhibitor
has_related_synonym: acetylserotonin O-methyltransferase inhibitors
has_related_synonym: acetylserotonin methyltransferase inhibitor
has_related_synonym: acetylserotonin methyltransferase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: hydroxyindole O-methyltransferase inhibitor
has_related_synonym: hydroxyindole O-methyltransferase inhibitors
has_related_synonym: hydroxyindole methyltransferase inhibitor
has_related_synonym: hydroxyindole methyltransferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

Sir2 inhibitor
type: Class
subclass of: EC 3.5.1.98 (histone deacetylase) inhibitor
definition: An EC 3.5.1.98 (histone deacetylase) inhibitor that interferes with the action of Sir2.
id: CHEBI:71181
has_related_synonym: Sir2 inhibitors
database_cross_reference: Wikipedia:Sir2
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

glucagon-like peptide-1 receptor agonist
type: Class
subclass of: G-protein-coupled receptor agonist
definition: An agonist that binds to and activates glucagon-like peptide-1 (GLP-1) receptors.
id: CHEBI:71196
has_related_synonym: GLP-1 receptor agonist
has_related_synonym: GLP-1 receptor agonists
database_cross_reference: Wikipedia:GLP-1_receptor
has_obo_namespace: chebi_ontology
has_related_synonym: glucagon-like peptide-1 receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

prohormone
type: Class
subclass of: biological role
definition: Any intra-glandular substance that acts as a precursor of a hormone, usually having minimal hormonal effect itself. Prohormones generally help in amplifying the effect of existing hormones.
id: CHEBI:71212
database_cross_reference: Wikipedia:Prohormone
has_obo_namespace: chebi_ontology
has_related_synonym: prohormones
in_subset: 3 STAR
imported from: chebi.owl

adenosine receptor antagonist
type: Class
subclass of: antagonist
definition: An antagonist at any adenosine receptor.
id: CHEBI:71232
database_cross_reference: Wikipedia:Adenosine_receptor
has_related_synonym: adenosine receptor antagonists
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 2.* (transferase) inhibitor
type: Class
subclass of: enzyme inhibitor
definition: An enzyme inhibitor that inhibits the action of a transferase (EC 2.*)
id: CHEBI:71300
has_related_synonym: EC 2 inhibitor
has_related_synonym: EC 2 inhibitors
has_related_synonym: EC 2.* (transferase) inhibitors
has_related_synonym: EC 2.* inhibitor
has_related_synonym: EC 2.* inhibitors
database_cross_reference: Wikipedia:Transferase
has_obo_namespace: chebi_ontology
has_related_synonym: transferase inhibitor
has_related_synonym: transferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

autoinducer
type: Class
subclass of: signalling molecule
definition: A signalling molecule produced and used by bacteria participating in quorum sensing, that is, in cell-cell communication to coordinate community-wide regulation of processes such as biofilm formation, virulence, and bioluminescence in populations of bacteria. Such communication can occur both within and between different species of bacteria.
id: CHEBI:71338
database_cross_reference: Wikipedia:Autoinducer
has_related_synonym: autoinducers
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 2.3.1.85 (fatty acid synthase) inhibitor
type: Class
subclass of: EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor
has_related_synonym: (FAS) inhibitors
definition: An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of fatty acid synthase (EC 2.3.1.85), a multi-enzyme protein involved in fatty acid synthesis.
id: CHEBI:71476
has_related_synonym: EC 2.3.1.85 (fatty acid synthase) inhibitors
has_related_synonym: EC 2.3.1.85 inhibitor
has_related_synonym: EC 2.3.1.85 inhibitors
database_cross_reference: Wikipedia:Fatty-acid_synthase
has_related_synonym: acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing) inhibitor
has_related_synonym: acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing) inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: fatty acid synthase (EC 2.3.1.85) inhibitor
has_related_synonym: fatty acid synthase (EC 2.3.1.85) inhibitors
has_related_synonym: fatty acid synthase inhibitor
has_related_synonym: fatty acid synthase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.5.1.23 (ceramidase) inhibitor
type: Class
subclass of: EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor
has_related_synonym: AC inhibitor
has_related_synonym: AC inhibitors
definition: An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of ceramidase (EC 3.5.1.23).
id: CHEBI:71551
has_related_synonym: EC 3.5.1.23 (ceramidase) inhibitors
has_related_synonym: EC 3.5.1.23 inhibitor
has_related_synonym: EC 3.5.1.23 inhibitors
has_related_synonym: N-acylsphingosine amidohydrolase inhibitor
has_related_synonym: N-acylsphingosine amidohydrolase inhibitors
has_related_synonym: acid ceramidase inhibitor
has_related_synonym: acid ceramidase inhibitors
has_related_synonym: acylsphingosine deacylase inhibitor
has_related_synonym: acylsphingosine deacylase inhibitors
has_related_synonym: ceramidase (EC 3.5.1.23) inhibitor
has_related_synonym: ceramidase (EC 3.5.1.23) inhibitors
has_related_synonym: ceramidase inhibitor
has_related_synonym: ceramidase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: glycosphingolipid ceramide deacylase inhibitor
has_related_synonym: glycosphingolipid ceramide deacylase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

PPARgamma agonist
type: Class
subclass of: agonist
subclass of: PPAR modulator
definition: A PPAR modulator which activates the peroxisome proliferator-activated receptor-gamma.
id: CHEBI:71554
has_related_synonym: PPAR-gamma agonist
has_related_synonym: PPAR-gamma agonists
has_exact_synonym: PPARgamma agonist
has_related_synonym: PPARgamma agonists
database_cross_reference: Wikipedia:Peroxisome_proliferator-activated_receptor_gamma
has_obo_namespace: chebi_ontology
has_related_synonym: peroxisome proliferator-activated receptor-gamma agonist
has_related_synonym: peroxisome proliferator-activated receptor-gamma agonists
in_subset: 3 STAR
imported from: chebi.owl

insect repellent
type: Class
subclass of: insecticide
definition: An insecticide that acts as a repellent to insects.
id: CHEBI:71692
database_cross_reference: Wikipedia:Insect_repellent
has_obo_namespace: chebi_ontology
has_related_synonym: insect repellents
in_subset: 3 STAR
imported from: chebi.owl

EC 3.1.4.35 (3',5'-cyclic-GMP phosphodiesterase) inhibitor
type: Class
subclass of: EC 3.1.4.* (phosphoric diester hydrolase) inhibitor
has_related_synonym: 3',5'-cyclic-GMP 5'-nucleotidohydrolase inhibitor
has_related_synonym: 3',5'-cyclic-GMP 5'-nucleotidohydrolase inhibitors
has_related_synonym: 3',5'-cyclic-GMP phosphodiesterase (EC 3.1.4.35) inhibitor
has_related_synonym: 3',5'-cyclic-GMP phosphodiesterase (EC 3.1.4.35) inhibitors
definition: An EC 3.1.4.* (phosphoric diester hydrolase) inhibitor that blocks the action of 3',5'-cyclic-GMP phosphodiesterase (EC 3.1.4.35).
id: CHEBI:71942
has_related_synonym: EC 3.1.4.35 (3',5'-cyclic-GMP phosphodiesterase) inhibitors
has_related_synonym: EC 3.1.4.35 inhibitor
has_related_synonym: EC 3.1.4.35 inhibitors
has_related_synonym: PDE5 inhibitor
has_related_synonym: PDE5 inhibitors
database_cross_reference: PMID:22996758
database_cross_reference: PMID:23343170
database_cross_reference: PMID:23346948
database_cross_reference: Wikipedia:CGMP-specific_phosphodiesterase_type_5
database_cross_reference: Wikipedia:PDE5_inhibitor
has_related_synonym: cGMP phosphodiesterase inhibitor
has_related_synonym: cGMP phosphodiesterase inhibitors
has_related_synonym: cGMP-PDE inhibitor
has_related_synonym: cGMP-PDE inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: cyclic 3',5'-GMP phosphodiesterase inhibitor
has_related_synonym: cyclic 3',5'-GMP phosphodiesterase inhibitors
has_related_synonym: cyclic GMP phosphodiesterase inhibitor
has_related_synonym: cyclic GMP phosphodiesterase inhibitors
has_related_synonym: cyclic guanosine 3',5'-monophosphate phosphodiesterase inhibitor
has_related_synonym: cyclic guanosine 3',5'-monophosphate phosphodiesterase inhibitors
has_related_synonym: cyclic guanosine 3',5'-phosphate phosphodiesterase inhibitor
has_related_synonym: cyclic guanosine 3',5'-phosphate phosphodiesterase inhibitors
has_related_synonym: guanosine cyclic 3',5'-phosphate phosphodiesterase inhibitor
has_related_synonym: guanosine cyclic 3',5'-phosphate phosphodiesterase inhibitors
has_related_synonym: phosphodiesterase 5 inhibitor
has_related_synonym: phosphodiesterase 5 inhibitors
has_related_synonym: phosphodiesterase V inhibitor
has_related_synonym: phosphodiesterase V inhibitors
has_related_synonym: type 5 phosphodiesterase inhibitor
has_related_synonym: type 5 phosphodiesterase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.5.1.88 (peptide deformylase) inhibitor
type: Class
subclass of: EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor
definition: An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of peptide deformylase (EC 3.5.1.88), involved in the catalytic removal of the N-terminal formyl group of nascent proteins.
id: CHEBI:71951
has_related_synonym: EC 3.5.1.88 (peptide deformylase) inhibitors
has_related_synonym: EC 3.5.1.88 inhibitor
has_related_synonym: EC 3.5.1.88 inhibitors
has_related_synonym: PDF inhibitors
database_cross_reference: Wikipedia:Peptide_deformylase
has_obo_namespace: chebi_ontology
has_related_synonym: formyl-L-methionyl peptide amidohydrolase inhibitor
has_related_synonym: formyl-L-methionyl peptide amidohydrolase inhibitors
has_related_synonym: peptide deformylase (EC 3.5.1.88) inhibitor
has_related_synonym: peptide deformylase (EC 3.5.1.88) inhibitors
has_related_synonym: peptide deformylase inhibitor
has_related_synonym: peptide deformylase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

nerve growth factor stimulator
type: Class
subclass of: neurotransmitter agent
definition: Any molecule shown to have the potentiality in stimulating the effect of nerve growth factor.
id: CHEBI:72294
has_related_synonym: NGF stimulator
has_related_synonym: NGF stimulators
has_obo_namespace: chebi_ontology
has_related_synonym: nerve growth factor stimulators
in_subset: 3 STAR
imported from: chebi.owl

MTP inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
definition: An inhibitor that interferes with the action of MTP.
id: CHEBI:72298
has_related_synonym: MTP inhibitors
has_related_synonym: MTTP inhibitor
has_related_synonym: MTTP inhibitors
database_cross_reference: Wikipedia:Microsomal_triglyceride_transfer_protein
has_obo_namespace: chebi_ontology
has_related_synonym: microsomal triglyceride transfer protein inhibitor
has_related_synonym: microsomal triglyceride transfer protein inhibitors
in_subset: 3 STAR
imported from: chebi.owl

glucagon-like peptide-2 receptor agonist
type: Class
subclass of: agonist
definition: An agonist that binds to and activates glucagon-like peptide-2 (GLP-2) receptors.
id: CHEBI:72311
has_related_synonym: GLP-2 receptor agonist
has_related_synonym: GLP-2 receptor agonists
database_cross_reference: Wikipedia:Glucagon-like_peptide_2_receptor
has_obo_namespace: chebi_ontology
has_related_synonym: glucagon-like peptide-2 receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

virulence factor
type: Class
subclass of: toxin
definition: Any toxin secreted by bacteria, viruses, fungi or protozoa enabling them to achieve colonisation of a niche in the host, inhibit or evade the host's immune response, enter and exit cells, or obtain nutrition from the host.
id: CHEBI:72316
database_cross_reference: PMID:22851449
database_cross_reference: Wikipedia:Virulence_factor
has_obo_namespace: chebi_ontology
has_related_synonym: virulence factors
in_subset: 3 STAR
imported from: chebi.owl

provitamin B1
type: Class
subclass of: provitamin
definition: A provitamin that can be converted into vitamin B1 by enzymes from animal tissues.
id: CHEBI:72470
has_obo_namespace: chebi_ontology
has_related_synonym: provitamin B1s
in_subset: 3 STAR
imported from: chebi.owl

vesicular glutamate transport inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
definition: An inhibitor that interferes with vesicular glutamate transport.
id: CHEBI:72483
database_cross_reference: Wikipedia:Vesicular_glutamate_transporter_1
has_obo_namespace: chebi_ontology
has_related_synonym: vesicular glutamate transport inhibitors
has_related_synonym: vesicular glutamate transporter 1 inhibitor
has_related_synonym: vesicular glutamate transporter 1 inhibitors
in_subset: 3 STAR
imported from: chebi.owl

pro-angiogenic agent
type: Class
subclass of: angiogenesis modulating agent
definition: Any compound that promotes the growth of new blood vessels from pre-existing vessels.
has_alternative_id: CHEBI:50927
id: CHEBI:72571
has_related_synonym: angiogenesis inducing agent
has_related_synonym: angiogenesis inducing agents
has_obo_namespace: chebi_ontology
has_related_synonym: pro-angiogenic agents
has_related_synonym: proangiogenic agent
has_related_synonym: proangiogenic agents
in_subset: 3 STAR
imported from: chebi.owl

alarm pheromone
type: Class
subclass of: pheromone
definition: A pheromone which is released by an organism when damaged by a predator which warns other individuals that there is a danger.
id: CHEBI:72575
database_cross_reference: PMID:20831948
database_cross_reference: PMID:22870255
has_related_synonym: alarm pheromones
has_related_synonym: alarm signal
has_related_synonym: alarm signals
has_related_synonym: alarm substance
has_related_synonym: alarm substances
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 2.3.2.13 (protein-glutamine gamma-glutamyltransferase) inhibitor
type: Class
subclass of: EC 2.3.2.* (aminoacyltransferase) inhibitor
definition: An EC 2.3.2.* (aminoacyltransferase) inhibitor that interferes with the action of protein-glutamine gamma-glutamyltransferase (EC 2.3.2.13).
id: CHEBI:72716
has_related_synonym: EC 2.3.2.13 (protein-glutamine gamma-glutamyltransferase) inhibitors
has_related_synonym: EC 2.3.2.13 inhibitor
has_related_synonym: EC 2.3.2.13 inhibitors
has_related_synonym: Factor XIIIa inhibitor
has_related_synonym: R-glutaminyl-peptide:amine gamma-glutamyl transferase inhibitor
has_related_synonym: TG-2 inhibitor
has_related_synonym: TG-2 inhibitors
has_related_synonym: TG2 inhibitor
has_related_synonym: TG2 inhibitors
has_related_synonym: TGase inhibitor
has_related_synonym: TGase inhibitors
database_cross_reference: Wikipedia:Transglutaminase
has_obo_namespace: chebi_ontology
has_related_synonym: fibrin stabilizing factor inhibitor
has_related_synonym: fibrin stabilizing factor inhibitors
has_related_synonym: fibrinoligase inhibitor
has_related_synonym: fibrinoligase inhibitors
has_related_synonym: glutaminylpeptide gamma-glutamyltransferase inhibitor
has_related_synonym: glutaminylpeptide gamma-glutamyltransferase inhibitors
has_related_synonym: polyamine transglutaminase inhibitor
has_related_synonym: polyamine transglutaminase inhibitors
has_related_synonym: protein-glutamine gamma-glutamyltransferase (EC 2.3.2.13) inhibitor
has_related_synonym: protein-glutamine gamma-glutamyltransferase (EC 2.3.2.13) inhibitors
has_related_synonym: protein-glutamine gamma-glutamyltransferase inhibitor
has_related_synonym: protein-glutamine gamma-glutamyltransferase inhibitors
has_related_synonym: protein-glutamine:amine gamma-glutamyltransferase inhibitor
has_related_synonym: protein-glutamine:amine gamma-glutamyltransferase inhibitors
has_related_synonym: tissue transglutaminase inhibitor
has_related_synonym: tissue transglutaminase inhibitors
has_related_synonym: transglutaminase inhibitor
has_related_synonym: transglutaminase inhibitors
has_related_synonym: transglutaminase-2 inhibitor
has_related_synonym: transglutaminase-2 inhibitors
in_subset: 3 STAR
imported from: chebi.owl

aryl hydrocarbon receptor agonist
type: Class
subclass of: agonist
has_related_synonym: AHR agonist
has_related_synonym: AHR agonists
has_related_synonym: AhR agonist
has_related_synonym: AhR agonists
definition: An agonist that binds to and activates aryl hydrocarbon receptors (AhRs).
id: CHEBI:72768
has_related_synonym: aryl hydrocarbon receptor agonists
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

breast cancer resistance protein inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
has_related_synonym: ABCG2 inhibitor
has_related_synonym: ABCG2 inhibitors
definition: Any inhibitor of breast cancer resistance protein (ABCG2).
id: CHEBI:72771
database_cross_reference: Wikipedia:ABCG2
has_related_synonym: breast cancer resistance protein inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

carotogenesis inhibitor
type: Class
subclass of: inhibitor
definition: Any inhibitor of the biosynthesis of carotenoids.
id: CHEBI:72773
has_related_synonym: carotogenesis inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 1.3.99.29 [phytoene desaturase (zeta-carotene-forming)] inhibitor
type: Class
subclass of: EC 1.3.99.* (oxidoreductase acting on donor CH-CH group, with other acceptors) inhibitor
has_related_synonym: 15-cis-phytoene:acceptor oxidoreductase (zeta-carotene-forming) inhibitor
has_related_synonym: 15-cis-phytoene:acceptor oxidoreductase (zeta-carotene-forming) inhibitors
has_related_synonym: 2-step phytoene desaturase inhibitor
has_related_synonym: 2-step phytoene desaturase inhibitors
definition: An EC 1.3.99.* (oxidoreductase acting on donor CH-CH group with other acceptors) inhibitor that interferes with the action of phytoene desaturase (zeta-carotene-forming), EC 1.3.99.29, an enzyme of carotenoid biosynthesis that converts phytoene into zeta-carotene (zeta-carotene) via the symmetrical introduction of two double bonds at the C-11 and C-11' positions of phytoene.
id: CHEBI:72774
has_related_synonym: CrtIa inhibitor
has_related_synonym: CrtIa inhibitors
has_related_synonym: EC 1.3.99.29 [phytoene desaturase (zeta-carotene-forming)] inhibitors
has_related_synonym: EC 1.3.99.29 inhibitor
has_related_synonym: EC 1.3.99.29 inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: phytoene dehydrogenase inhibitor
has_related_synonym: phytoene dehydrogenase inhibitors
has_related_synonym: phytoene desaturase (zeta-carotene-forming) (EC 1.3.99.29) inhibitor
has_related_synonym: phytoene desaturase (zeta-carotene-forming) (EC 1.3.99.29) inhibitors
has_related_synonym: phytoene desaturase (zeta-carotene-forming) inhibitor
has_related_synonym: phytoene desaturase (zeta-carotene-forming) inhibitors
has_related_synonym: phytoene desaturase inhibitor
has_related_synonym: phytoene desaturase inhibitors
has_related_synonym: two-step phytoene desaturase inhibitor
has_related_synonym: two-step phytoene desaturase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.13.11.52 (indoleamine 2,3-dioxygenase) inhibitor
type: Class
subclass of: EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitor
definition: An EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 atoms of oxygen) inhibitor that interferes with the action of indoleamine 2,3-dioxygenase (EC 1.13.11.52).
id: CHEBI:72854
has_related_synonym: D-tryptophan:oxygen 2,3-oxidoreductase (decyclizing) inhibitor
has_related_synonym: D-tryptophan:oxygen 2,3-oxidoreductase (decyclizing) inhibitors
has_related_synonym: EC 1.13.11.52 (indoleamine 2,3-dioxygenase) inhibitors
has_related_synonym: EC 1.13.11.52 inhibitor
has_related_synonym: EC 1.13.11.52 inhibitors
has_related_synonym: IDO inhibitor
has_related_synonym: IDO inhibitors
database_cross_reference: Wikipedia:Indoleamine_2,3-dioxygenase
has_obo_namespace: chebi_ontology
has_related_synonym: indoleamine 2,3-dioxygenase (EC 1.13.11.52) inhibitor
has_related_synonym: indoleamine 2,3-dioxygenase (EC 1.13.11.52) inhibitors
has_related_synonym: indoleamine 2,3-dioxygenase inhibitor
has_related_synonym: indoleamine 2,3-dioxygenase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.1.1.184 [carbonyl reductase (NADPH)] inhibitor
type: Class
subclass of: EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor
has_related_synonym: ALR3 inhibitor
has_related_synonym: ALR3 inhibitors
definition: An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of carbonyl reductase (NADPH), EC 1.1.1.184.
id: CHEBI:73136
has_related_synonym: EC 1.1.1.184 (carbonyl reductase (NADPH)) inhibitor
has_related_synonym: EC 1.1.1.184 (carbonyl reductase (NADPH)) inhibitors
has_related_synonym: EC 1.1.1.184 [carbonyl reductase (NADPH)] inhibitors
has_related_synonym: EC 1.1.1.184 inhibitor
has_related_synonym: EC 1.1.1.184 inhibitors
has_related_synonym: NADPH2-dependent carbonyl reductase inhibitor
has_related_synonym: NADPH2-dependent carbonyl reductase inhibitors
database_cross_reference: Wikipedia:Carbonyl_reductase_(NADPH)
has_related_synonym: aldehyde reductase 1 inhibitor
has_related_synonym: aldehyde reductase 1 inhibitors
has_related_synonym: carbonyl reductase (NADPH) (EC 1.1.1.184) inhibitor
has_related_synonym: carbonyl reductase (NADPH) (EC 1.1.1.184) inhibitors
has_related_synonym: carbonyl reductase (NADPH) inhibitor
has_related_synonym: carbonyl reductase (NADPH) inhibitors
has_related_synonym: carbonyl reductase (NADPH2) inhibitor
has_related_synonym: carbonyl reductase (NADPH2) inhibitors
has_related_synonym: carbonyl reductase inhibitor
has_related_synonym: carbonyl reductase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: nonspecific NADPH-dependent carbonyl reductase inhibitor
has_related_synonym: nonspecific NADPH-dependent carbonyl reductase inhibitors
has_related_synonym: prostaglandin 9-ketoreductase inhibitor
has_related_synonym: prostaglandin 9-ketoreductase inhibitors
has_related_synonym: secondary-alcohol:NADP+ oxidoreductase inhibitor
has_related_synonym: secondary-alcohol:NADP+ oxidoreductase inhibitors
has_related_synonym: xenobiotic ketone reductase inhibitor
has_related_synonym: xenobiotic ketone reductase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor
type: Class
subclass of: EC 1.11.1.* (peroxidases) inhibitor
definition: An EC 1.11.1.* (peroxidases) inhibitor that inhibits the action of L-ascorbate peroxidase (EC 1.11.1.11).
id: CHEBI:73181
has_related_synonym: EC 1.11.1.11 (L-ascorbate peroxidase) inhibitors
has_related_synonym: EC 1.11.1.11 inhibitor
has_related_synonym: EC 1.11.1.11 inhibitors
has_related_synonym: L-ascorbate peroxidase (EC 1.11.1.11) inhibitor
has_related_synonym: L-ascorbate peroxidase (EC 1.11.1.11) inhibitors
has_related_synonym: L-ascorbate peroxidase inhibitor
has_related_synonym: L-ascorbate peroxidase inhibitors
has_related_synonym: L-ascorbate:hydrogen-peroxide oxidoreductase inhibitor
has_related_synonym: L-ascorbate:hydrogen-peroxide oxidoreductase inhibitors
has_related_synonym: L-ascorbic acid peroxidase inhibitor
has_related_synonym: L-ascorbic acid peroxidase inhibitors
has_related_synonym: L-ascorbic acid-specific peroxidase inhibitor
has_related_synonym: L-ascorbic acid-specific peroxidase inhibitors
database_cross_reference: Wikipedia:L-ascorbate_peroxidase
has_related_synonym: ascorbate peroxidase inhibitor
has_related_synonym: ascorbate peroxidase inhibitors
has_related_synonym: ascorbic acid peroxidase inhibitor
has_related_synonym: ascorbic acid peroxidase inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

plant activator
type: Class
subclass of: agrochemical
definition: Any compound that protects plants by activating their defence mechanisms.
id: CHEBI:73182
has_obo_namespace: chebi_ontology
has_related_synonym: plant activators
in_subset: 3 STAR
imported from: chebi.owl

brassinosteroid biosynthesis inhibitor
type: Class
subclass of: inhibitor
definition: Any compound that inhibits one or more steps in the pathway leading to the synthesis of brassinosteroids.
id: CHEBI:73189
database_cross_reference: PMID:10462767
has_related_synonym: brassinosteroid biosynthesis inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

antimutagen
type: Class
subclass of: biological role
definition: An agent that reduces or interferes with the mutagenic actions or effects of a substance.
id: CHEBI:73190
has_related_synonym: antimutagenic agent
has_related_synonym: antimutagenic agents
has_related_synonym: antimutagens
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

abscisic acid receptor agonist
type: Class
subclass of: agonist
has_related_synonym: ABA agonist
has_related_synonym: ABA agonists
has_related_synonym: ABA receptor agonist
has_related_synonym: ABA receptor agonists
definition: An agonist that binds to and activates abscisic acid receptors.
id: CHEBI:73191
has_related_synonym: abscisic acid receptor agonists
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor
type: Class
subclass of: EC 1.3.3.* (oxidoreductase acting on donor CH-CH group, oxygen as acceptor) inhibitor
definition: An EC 1.3.3.* (oxidoreductase acting on donor CH-CH group with oxygen as acceptor) inhibitor that interferes with the action of protoporphyrinogen oxidase (EC 1.3.3.4).
id: CHEBI:73192
has_related_synonym: EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitors
has_related_synonym: EC 1.3.3.4 inhibitor
has_related_synonym: EC 1.3.3.4 inhibitors
has_related_synonym: HemG inhibitor
has_related_synonym: HemG inhibitors
has_related_synonym: HemY inhibitor
has_related_synonym: HemY inhibitors
database_cross_reference: PMID:15660355
database_cross_reference: PMID:22273380
has_related_synonym: PPO inhibitor
has_related_synonym: PPO inhibitors
has_related_synonym: Protox inhibitor
has_related_synonym: Protox inhibitors
database_cross_reference: Wikipedia:Protoporphyrinogen_oxidase
has_obo_namespace: chebi_ontology
has_related_synonym: protoporphyrinogen IX oxidase inhibitor
has_related_synonym: protoporphyrinogen IX oxidase inhibitors
has_related_synonym: protoporphyrinogen oxidase (EC 1.3.3.4) inhibitor
has_related_synonym: protoporphyrinogen oxidase (EC 1.3.3.4) inhibitors
has_related_synonym: protoporphyrinogen oxidase inhibitor
has_related_synonym: protoporphyrinogen oxidase inhibitors
has_related_synonym: protoporphyrinogen-IX:oxygen oxidoreductase inhibitor
has_related_synonym: protoporphyrinogen-IX:oxygen oxidoreductase inhibitors
has_related_synonym: protoporphyrinogenase inhibitor
has_related_synonym: protoporphyrinogenase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

gibberellin biosynthesis inhibitor
type: Class
subclass of: inhibitor
definition: Any compound that inhibits one or more steps in the pathway leading to the synthesis of gibberellins.
id: CHEBI:73193
has_obo_namespace: chebi_ontology
has_related_synonym: gibberellin biosynthesis inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 4.4.1.11 (methionine gamma-lyase) inhibitor
type: Class
subclass of: EC 4.4.1.* (C-S lyase) inhibitor
definition: An EC 4.4.1.* (C-S lyase) inhibitor that interferes with the action of the enzyme methionine gamma-lyase (EC 4.4.1.11).
id: CHEBI:73196
has_related_synonym: EC 4.4.1.11 (methionine gamma-lyase) inhibitors
has_related_synonym: L-methioninase inhibitor
has_related_synonym: L-methioninase inhibitors
database_cross_reference: Wikipedia:Methionine_gamma-lyase
has_obo_namespace: chebi_ontology
has_related_synonym: methioninase inhibitor
has_related_synonym: methioninase inhibitors
has_related_synonym: methionine gamma-lyase (EC 4.4.1.11) inhibitor
has_related_synonym: methionine gamma-lyase (EC 4.4.1.11) inhibitors
has_related_synonym: methionine gamma-lyase inhibitor
has_related_synonym: methionine gamma-lyase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.6.3.14 (H(+)-transporting two-sector ATPase) inhibitor
type: Class
subclass of: EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor
has_related_synonym: ATP phosphohydrolase (H(+)-transporting) inhibitor
has_related_synonym: ATP phosphohydrolase (H(+)-transporting) inhibitors
has_related_synonym: ATP synthase inhibitor
has_related_synonym: ATP synthase inhibitors
definition: An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of H(+)-transporting two-sector ATPase inhibitor (EC 3.6.3.14).
id: CHEBI:73214
has_related_synonym: EC 3.6.3.14 (H(+)-transporting two-sector ATPase) inhibitors
has_related_synonym: EC 3.6.3.14 inhibitor
has_related_synonym: EC 3.6.3.14 inhibitors
has_related_synonym: F1-ATPase inhibitor
has_related_synonym: F1-ATPase inhibitors
has_related_synonym: FoF1-ATPase inhibitor
has_related_synonym: FoF1-ATPase inhibitors
has_related_synonym: H(+)-transporting ATPase inhibitor
has_related_synonym: H(+)-transporting ATPase inhibitors
has_related_synonym: H(+)-transporting two-sector ATPase (EC 3.6.3.14) inhibitor
has_related_synonym: H(+)-transporting two-sector ATPase (EC 3.6.3.14) inhibitors
has_related_synonym: H(+)-transporting two-sector ATPase inhibitor
has_related_synonym: H(+)-transporting two-sector ATPase inhibitors
database_cross_reference: Wikipedia:ATP_synthase
has_related_synonym: bacterial Ca(2+)/Mg(2+) ATPase inhibitor
has_related_synonym: bacterial Ca(2+)/Mg(2+) ATPase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: chloroplast ATPase inhibitor
has_related_synonym: chloroplast ATPase inhibitors
has_related_synonym: coupling factors (Fo, F1 and CF1) inhibitor
has_related_synonym: coupling factors (Fo, F1 and CF1) inhibitors
has_related_synonym: mitochondrial ATPase inhibitor
has_related_synonym: mitochondrial ATPase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor
type: Class
subclass of: EC 3.* (hydrolase) inhibitor
definition: Any hydrolase inhibitor that interferes with the action of a hydrolase which acts on acid anhydrides (EC 3.6.*.*).
id: CHEBI:73216
has_alternative_id: CHEBI:76765
has_related_synonym: EC 3.6 inhibitor
has_related_synonym: EC 3.6 inhibitors
has_related_synonym: EC 3.6.* (hydrolases acting on acid anhydrides) inhibitors
has_related_synonym: EC 3.6.* inhibitor
has_related_synonym: EC 3.6.* inhibitors
has_related_synonym: EC 3.6.*.* inhibitor
has_related_synonym: EC 3.6.*.* inhibitors
has_related_synonym: acid anhydride hydrolase inhibitor
has_related_synonym: acid anhydride hydrolase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of hydrolase acting on acid anhydride (EC 3.6.*)
has_related_synonym: inhibitors of hydrolase acting on acid anhydride (EC 3.6.*)
in_subset: 3 STAR
imported from: chebi.owl

NF-kappaB inhibitor
type: Class
subclass of: inhibitor
definition: An inhibitor of NF-kappaB (nuclear factor kappa-light-chain-enhancer of activated B cells), a protein complex involved in the transcription of DNA.
id: CHEBI:73240
has_related_synonym: NF-kB inhibitor
has_related_synonym: NF-kB inhibitors
has_exact_synonym: NF-kappaB inhibitor
has_related_synonym: NF-kappaB inhibitors
has_related_synonym: Nuclear factor kappa B inhibitor
has_related_synonym: Nuclear factor kappa B inhibitors
database_cross_reference: Wikipedia:NF-%CE%BAB
has_obo_namespace: chebi_ontology
has_related_synonym: nuclear factor kappa-light-chain-enhancer of activated B cells inhibitor
has_related_synonym: nuclear factor kappa-light-chain-enhancer of activated B cells inhibitors
in_subset: 3 STAR
imported from: chebi.owl

cyclooxygenase 3 inhibitor
type: Class
subclass of: EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor
definition: A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 3.
id: CHEBI:73263
has_related_synonym: COX-3 inhibitor
has_related_synonym: COX-3 inhibitors
database_cross_reference: PMID:12242329
database_cross_reference: PMID:12374850
database_cross_reference: PMID:14592546
database_cross_reference: Wikipedia:COX-3
has_obo_namespace: chebi_ontology
has_related_synonym: cyclo-oxygenase 3 inhibitor
has_related_synonym: cyclo-oxygenase 3 inhibitors
has_related_synonym: cyclooxygenase 3 inhibitors
has_related_synonym: cyclooxygenase-3 inhibitor
has_related_synonym: cyclooxygenase-3 inhibitors
in_subset: 3 STAR
imported from: chebi.owl

oxidative phosphorylation inhibitor
type: Class
subclass of: inhibitor
definition: Any compound that inhibits oxidative phosphorylation.
id: CHEBI:73267
has_obo_namespace: chebi_ontology
has_related_synonym: oxidative phosphorylation inhibitors
in_subset: 3 STAR
imported from: chebi.owl

sodium-glucose transport protein subtype 2 inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
definition: Any inhibitor that interferes with the action of sodium-glucose transport protein subtype 2.
id: CHEBI:73273
has_related_synonym: SGLT2 inhibitor
has_related_synonym: SGLT2 inhibitors
database_cross_reference: Wikipedia:Sodium/glucose_cotransporter_2
has_obo_namespace: chebi_ontology
has_related_synonym: sodium glucose co-transporter 2 inhibitor
has_related_synonym: sodium glucose co-transporter 2 inhibitors
has_related_synonym: sodium-glucose transport protein subtype 2 inhibitors
has_related_synonym: sodium/glucose cotransporter 2 inhibitor
has_related_synonym: sodium/glucose cotransporter 2 inhibitors
in_subset: 3 STAR
imported from: chebi.owl

cholecystokinin antagonist
type: Class
subclass of: hormone antagonist
definition: A hormone antagonist that inhibits the action of the peptide hormone cholecystokinin.
has_related_synonym: CCK antagonist
has_related_synonym: CCK antagonists
id: CHEBI:73296
database_cross_reference: Wikipedia:Cholecystokinin_antagonist
has_obo_namespace: chebi_ontology
has_related_synonym: cholecystokinin antagonists
in_subset: 3 STAR
imported from: chebi.owl

adenosine A2A receptor agonist
type: Class
subclass of: adenosine receptor agonist
has_related_synonym: A2A agonist
has_related_synonym: A2A agonists
has_related_synonym: A2A receptor agonist
has_related_synonym: A2A receptor agonists
definition: An agonist at the A2A receptor.
id: CHEBI:73310
database_cross_reference: Wikipedia:Adenosine_A2A_receptor
has_related_synonym: adenosine A2A receptor agonists
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

adenosine receptor agonist
type: Class
subclass of: agonist
definition: An agonist at any adenosine receptor.
id: CHEBI:73311
has_exact_synonym: adenosine receptor agonist
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

adenosine A3 receptor agonist
type: Class
subclass of: adenosine receptor agonist
has_related_synonym: A3 agonist
has_related_synonym: A3 agonists
has_related_synonym: A3 receptor agonist
has_related_synonym: A3 receptor agonists
definition: An agonist at the adenosine A3 receptor.
id: CHEBI:73319
database_cross_reference: Wikipedia:Adenosine_A3_receptor
has_related_synonym: adenosine A3 receptor agonists
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

scabicide
type: Class
subclass of: acaricide
definition: An acaricide that kills mites of the genus Sarcoptes.
id: CHEBI:73333
database_cross_reference: Wikipedia:Scabicide
has_obo_namespace: chebi_ontology
has_related_synonym: scabicides
in_subset: 3 STAR
imported from: chebi.owl

thyroid hormone agonist
type: Class
subclass of: hormone agonist
definition: A hormone agonist that binds to and activates a thyroid hormone receptor.
id: CHEBI:73334
database_cross_reference: Wikipedia:Thyroid_hormone_receptor
has_obo_namespace: chebi_ontology
has_related_synonym: thyroid hormone agonists
has_related_synonym: thyromimetic
has_related_synonym: thyromimetics
in_subset: 3 STAR
imported from: chebi.owl

ultraviolet filter
type: Class
subclass of: photochemical role
definition: A photochemical role realized in the absorption of ultraviolet light, for example to protect skin cells from damage.
id: CHEBI:73335
has_related_synonym: UV filter
has_related_synonym: UV filters
database_cross_reference: Wikipedia:UV_filter
has_obo_namespace: chebi_ontology
has_related_synonym: ultraviolet filters
in_subset: 3 STAR
imported from: chebi.owl

vulnerary
type: Class
subclass of: drug
definition: A drug used in treating and healing of wounds.
id: CHEBI:73336
database_cross_reference: Wikipedia:Wound_healing
has_obo_namespace: chebi_ontology
has_related_synonym: vulneraries
has_related_synonym: wound-healing agent
has_related_synonym: wound-healing agents
has_related_synonym: wound-healing drug
has_related_synonym: wound-healing drugs
in_subset: 3 STAR
imported from: chebi.owl

protein-sequencing agent
type: Class
subclass of: application
definition: Any agent used to determine the amino-acid sequence in a polypeptide.
id: CHEBI:73352
has_obo_namespace: chebi_ontology
has_related_synonym: protein-sequencing agents
has_related_synonym: sequencing agent
has_related_synonym: sequencing agents
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.3.2 (creatine kinase) inhibitor
type: Class
subclass of: EC 2.7.3.* (phosphotransferases with a nitrogenous group as acceptor) inhibitor
definition: An EC 2.7.3.* (phosphotransferases with a nitrogenous group as acceptor) inhibitor that interferes with the action of creatine kinase, EC 2.7.3.2.
id: CHEBI:73354
has_related_synonym: CK inhibitor
has_related_synonym: CK inhibitors
has_related_synonym: CPK inhibitor
has_related_synonym: CPK inhibitors
has_related_synonym: EC 2.7.3.2 (creatine kinase) inhibitors
database_cross_reference: Wikipedia:Creatine_kinase
has_obo_namespace: chebi_ontology
has_related_synonym: creatine kinase (EC 2.7.3.2) inhibitor
has_related_synonym: creatine kinase (EC 2.7.3.2) inhibitors
has_related_synonym: creatine kinase inhibitor
has_related_synonym: creatine kinase inhibitors
has_related_synonym: creatine phosphokinase inhibitor
has_related_synonym: creatine phosphokinase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.11.18 (methionyl aminopeptidase) inhibitor
type: Class
subclass of: EC 3.4.11.* (aminopeptidase) inhibitor
definition: Any EC 3.4.11.* (aminopeptidase) inhibitor that interferes with the action of methionyl aminopeptidase (EC 3.4.11.18).
id: CHEBI:73360
has_related_synonym: EC 3.4.11.18 (methionyl aminopeptidase) inhibitors
has_related_synonym: EC 3.4.11.18 inhibitor
has_related_synonym: EC 3.4.11.18 inhibitors
has_related_synonym: L-methionine aminopeptidase inhibitor
has_related_synonym: L-methionine aminopeptidase inhibitors
has_related_synonym: MAP inhibitor
has_related_synonym: MAP inhibitors
database_cross_reference: Wikipedia:Methionyl_aminopeptidase
has_obo_namespace: chebi_ontology
has_related_synonym: methionine aminopeptidase inhibitor
has_related_synonym: methionine aminopeptidase inhibitors
has_related_synonym: methionyl aminopeptidase (EC 3.4.11.18) inhibitor
has_related_synonym: methionyl aminopeptidase (EC 3.4.11.18) inhibitors
has_related_synonym: methionyl aminopeptidase inhibitor
has_related_synonym: methionyl aminopeptidase inhibitors
has_related_synonym: peptidase M inhibitor
has_related_synonym: peptidase M inhibitors
in_subset: 3 STAR
imported from: chebi.owl

methionine aminopeptidase 2 inhibitor
type: Class
subclass of: EC 3.4.11.18 (methionyl aminopeptidase) inhibitor
definition: Any methionyl aminopeptidase inhibitor that inhibits the action of methionyl aminopeptidase 2.
id: CHEBI:73361
has_related_synonym: MAP2 inhibitor
has_related_synonym: MAP2 inhibitors
has_related_synonym: METAP2 inhibitor
has_related_synonym: METAP2 inhibitors
has_related_synonym: MetAP2 inhibitor
has_related_synonym: MetAP2 inhibitors
database_cross_reference: Wikipedia:METAP2
has_obo_namespace: chebi_ontology
has_related_synonym: methionine aminopeptidase 2 inhibitors
has_related_synonym: methionine aminopeptidase-2 inhibitor
has_related_synonym: methionine aminopeptidase-2 inhibitors
in_subset: 3 STAR
imported from: chebi.owl

cannabinoid receptor antagonist
type: Class
subclass of: antagonist
definition: An antagonist that binds to and deactivates cannabinoid receptors.
id: CHEBI:73413
database_cross_reference: Wikipedia:Cannabinoid_receptor
has_related_synonym: cannabinoid receptor antagonists
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

CB1 receptor antagonist
type: Class
subclass of: cannabinoid receptor antagonist
definition: An antagonist that binds to and deactivates type 1 cannabinoid receptors.
has_exact_synonym: CB1 receptor antagonist
has_related_synonym: CB1 receptor antagonists
has_related_synonym: CB1R antagonist
has_related_synonym: CB1R antagonists
id: CHEBI:73416
database_cross_reference: PMID:22463610
database_cross_reference: Wikipedia:Cannabinoid_receptor_type_1
has_related_synonym: cannabinoid receptor 1 antagonist
has_related_synonym: cannabinoid receptor 1 antagonists
has_related_synonym: cannabinoid receptor type 1 antagonist
has_related_synonym: cannabinoid receptor type 1 antagonists
has_obo_namespace: chebi_ontology
has_related_synonym: type 1 cannabinoid receptor antagonist
has_related_synonym: type 1 cannabinoid receptor antagonists
in_subset: 3 STAR
imported from: chebi.owl

CB2 receptor antagonist
type: Class
subclass of: cannabinoid receptor antagonist
definition: An antagonist that binds to and deactivates type 2 cannabinoid receptors.
has_exact_synonym: CB2 receptor antagonist
has_related_synonym: CB2 receptor antagonists
has_related_synonym: CB2R antagonist
has_related_synonym: CB2R antagonists
id: CHEBI:73417
database_cross_reference: Wikipedia:Cannabinoid_receptor_type_2
has_related_synonym: cannabinoid receptor 2 antagonist
has_related_synonym: cannabinoid receptor 2 antagonists
has_related_synonym: cannabinoid receptor type 2 antagonist
has_related_synonym: cannabinoid receptor type 2 antagonists
has_obo_namespace: chebi_ontology
has_related_synonym: type 2 cannabinoid receptor antagonist
has_related_synonym: type 2 cannabinoid receptor antagonists
in_subset: 3 STAR
imported from: chebi.owl

kynuramine
type: Class
subclass of: molecular entity
charge: 0
monoisotopicmass: 164.09496
mass: 164.20440
has_related_synonym: 2',3-diaminopropiophenone
has_related_synonym: 3-amino-1-(2-aminophenyl)-1-propanone
has_exact_synonym: 3-amino-1-(2-aminophenyl)propan-1-one
definition: A member of the class of kynurenamines that is aniline substituted at position 2 by a 3-aminopropanoyl group.
formula: C9H12N2O
database_cross_reference: CAS:363-36-0
has_alternative_id: CHEBI:24989
id: CHEBI:73472
database_cross_reference: Chemspider:9311
database_cross_reference: FooDB:FDB028888
database_cross_reference: HMDB:HMDB0012246
inchi: InChI=1S/C9H12N2O/c10-6-5-9(12)7-3-1-2-4-8(7)11/h1-4H,5-6,10-11H2
smiles: NCCC(=O)c1ccccc1N
database_cross_reference: PMID:13843767
database_cross_reference: PMID:14332461
database_cross_reference: PMID:22547660
database_cross_reference: PMID:3428356
database_cross_reference: PMID:34648288
database_cross_reference: PMID:3572806
database_cross_reference: PMID:4017223
database_cross_reference: PMID:4384132
database_cross_reference: PMID:497017
database_cross_reference: PMID:510362
database_cross_reference: PMID:5472592
database_cross_reference: PMID:562342
database_cross_reference: PMID:6115758
database_cross_reference: PMID:6132830
database_cross_reference: PMID:6140297
database_cross_reference: PMID:6503615
database_cross_reference: PMID:6519183
database_cross_reference: PMID:6877035
database_cross_reference: Patent:WO2006061140
inchikey: QLPVTIQQFGWSQQ-UHFFFAOYSA-N
database_cross_reference: Reaxys:2802772
has_obo_namespace: chebi_ontology
has_related_synonym: kynurenamine
in_subset: 3 STAR
imported from: chebi.owl

spectrophotometric reagent
type: Class
subclass of: reagent
definition: A reagent used in the determination by spectrophotometry of the concentration of a chemical element or chemical compound in solution.
id: CHEBI:73618
has_obo_namespace: chebi_ontology
has_related_synonym: spectrophotometric reagents
in_subset: 3 STAR
imported from: chebi.owl

tolerogen
type: Class
subclass of: biological role
definition: A substance that invokes a specific immune non-responsiveness due to its molecular form. If its molecular form is changed, a tolerogen can become an immunogen.
id: CHEBI:73623
has_obo_namespace: chebi_ontology
has_related_synonym: tolerogens
in_subset: 3 STAR
imported from: chebi.owl

peptide coupling reagent
type: Class
subclass of: reagent
definition: A reagent used to couple amino acids during artificial peptide synthesis.
id: CHEBI:73668
has_obo_namespace: chebi_ontology
has_related_synonym: peptide coupling reagents
in_subset: 3 STAR
imported from: chebi.owl

PPARbeta/delta agonist
type: Class
subclass of: agonist
subclass of: PPAR modulator
definition: A PPAR modulator which activates the peroxisome proliferator-activated receptor-beta/delta.
has_alternative_id: CHEBI:73729
id: CHEBI:73730
has_related_synonym: NR1C2 agonist
has_related_synonym: NR1C2 agonists
has_related_synonym: PPAR(beta/delta) agonist
has_related_synonym: PPAR(beta/delta) agonists
has_related_synonym: PPAR-beta agonist
has_related_synonym: PPAR-beta agonists
has_related_synonym: PPAR-beta/delta agonist
has_related_synonym: PPAR-beta/delta agonists
has_related_synonym: PPAR-delta agonist
has_related_synonym: PPAR-delta agonists
has_related_synonym: PPARD agonist
has_related_synonym: PPARD agonists
has_related_synonym: PPARD receptor agonist
has_related_synonym: PPARD receptor agonists
has_related_synonym: PPARbeta agonist
has_related_synonym: PPARbeta agonists
has_exact_synonym: PPARbeta/delta agonist
has_related_synonym: PPARbeta/delta agonists
has_related_synonym: PPARdelta agonist
has_related_synonym: PPARdelta agonists
database_cross_reference: Wikipedia:Peroxisome_proliferator-activated_receptor_delta
has_obo_namespace: chebi_ontology
has_related_synonym: nuclear receptor subfamily 1, group C, member 2 agonist
has_related_synonym: nuclear receptor subfamily 1, group C, member 2 agonists
has_related_synonym: peroxisome proliferator-activated receptor-beta agonist
has_related_synonym: peroxisome proliferator-activated receptor-beta agonists
has_related_synonym: peroxisome proliferator-activated receptor-delta agonist
has_related_synonym: peroxisome proliferator-activated receptor-delta agonists
in_subset: 3 STAR
imported from: chebi.owl

vibriostatic agent
type: Class
subclass of: antibacterial agent
definition: Any compound that inhibits the growth of bacteria of the genus Vibrio.
id: CHEBI:73911
has_obo_namespace: chebi_ontology
has_related_synonym: vibriostatic
has_related_synonym: vibriostatics
in_subset: 3 STAR
imported from: chebi.owl

antifolate
type: Class
subclass of: antimetabolite
definition: An antimetabolite that impairs the action of folic acids
id: CHEBI:73913
database_cross_reference: Wikipedia:Antifolate
has_related_synonym: antifolates
has_obo_namespace: chebi_ontology
has_related_synonym: folic acid antagonist
has_related_synonym: folic acid antagonists
in_subset: 3 STAR
imported from: chebi.owl

nitric oxide synthase activator
type: Class
subclass of: enzyme activator
definition: Any compound that binds to and activates the enzyme nitric oxide synthase (EC 1.14.13.39).
id: CHEBI:73966
has_related_synonym: NOS activator
has_related_synonym: NOS activators
database_cross_reference: Wikipedia:Nitric_oxide_synthase
has_obo_namespace: chebi_ontology
has_related_synonym: nitric oxide synthase activators
in_subset: 3 STAR
imported from: chebi.owl

lachrymator
type: Class
subclass of: biophysical role
definition: Any substance that stimulates the corneal nerves in the eves to cause tears.
id: CHEBI:74136
database_cross_reference: PMID:4919431
has_obo_namespace: chebi_ontology
has_related_synonym: lachrymators
in_subset: 3 STAR
imported from: chebi.owl

mordant
type: Class
subclass of: application
id: CHEBI:74152
definition: Substance used to set dyes on fabrics or tissue sections by forming a coordination complex with the dye which then attaches to the fabric or tissue.
database_cross_reference: Wikipedia:Mordant
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor
type: Class
subclass of: EC 1.17.4.* (oxidoreductase acting on CH or CH2 with a disulfide as acceptor) inhibitor
has_related_synonym: 2'-deoxyribonucleoside-diphosphate:thioredoxin-disulfide 2'-oxidoreductase inhibitor
has_related_synonym: 2'-deoxyribonucleoside-diphosphate:thioredoxin-disulfide 2'-oxidoreductase inhibitors
has_related_synonym: ADP reductase inhibitor
has_related_synonym: ADP reductase inhibitors
definition: An EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitor that inhibits the action of ribonucleoside-diphosphate reductase (EC 1.17.4.1).
has_related_synonym: CDP reductase inhibitor
has_related_synonym: CDP reductase inhibitors
id: CHEBI:74213
has_related_synonym: EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitors
has_related_synonym: EC 1.17.4.1 inhibitor
has_related_synonym: EC 1.17.4.1 inhibitors
has_related_synonym: RR inhibitor
has_related_synonym: RR inhibitors
has_related_synonym: UDP reductase inhibitor
has_related_synonym: UDP reductase inhibitors
database_cross_reference: Wikipedia:Ribonucleoside-diphosphate_reductase
has_obo_namespace: chebi_ontology
has_related_synonym: nucleoside diphosphate reductase inhibitor
has_related_synonym: nucleoside diphosphate reductase inhibitors
has_related_synonym: ribonucleoside diphosphate reductase inhibitor
has_related_synonym: ribonucleoside diphosphate reductase inhibitors
has_related_synonym: ribonucleoside-diphosphate reductase (EC 1.17.4.1) inhibitor
has_related_synonym: ribonucleoside-diphosphate reductase (EC 1.17.4.1) inhibitors
has_related_synonym: ribonucleoside-diphosphate reductase inhibitor
has_related_synonym: ribonucleoside-diphosphate reductase inhibitors
has_related_synonym: ribonucleotide diphosphate reductase inhibitor
has_related_synonym: ribonucleotide diphosphate reductase inhibitors
has_related_synonym: ribonucleotide reductase inhibitor
has_related_synonym: ribonucleotide reductase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.1.1.153 [sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)] inhibitor
type: Class
subclass of: EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor
has_related_synonym: 7,8-dihydrobiopterin:NADP(+) oxidoreductase
has_related_synonym: 7,8-dihydrobiopterin:NADP(+) oxidoreductases
definition: An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the activity of sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming), EC 1.1.1.153, which plays an important part in the biosynthesis of tetrahydrobiopterin.
id: CHEBI:74234
has_related_synonym: EC 1.1.1.153 (sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)) inhibitor
has_related_synonym: EC 1.1.1.153 (sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)) inhibitors
has_related_synonym: EC 1.1.1.153 [sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)] inhibitors
has_related_synonym: L-erythro-7,8-dihydrobiopterin:NADP(+) oxidoreductase inhibitor
has_related_synonym: L-erythro-7,8-dihydrobiopterin:NADP(+) oxidoreductase inhibitors
database_cross_reference: Wikipedia:Sepiapterin_reductase
has_obo_namespace: chebi_ontology
has_related_synonym: sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming) (EC 1.1.1.153) inhibitor
has_related_synonym: sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming) (EC 1.1.1.153) inhibitors
has_related_synonym: sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming) inhibitor
has_related_synonym: sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming) inhibitors
has_related_synonym: sepiapterin reductase inhibitor
has_related_synonym: sepiapterin reductase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

polymerisation monomer
type: Class
subclass of: chemical role
definition: Any compound used as a monomer for a polymerisation process. The term is generally used in relation to industrial polymerisation processes.
id: CHEBI:74236
has_obo_namespace: chebi_ontology
has_related_synonym: polymerization monomer
in_subset: 3 STAR
imported from: chebi.owl

quinol oxidation site inhibitor
type: Class
subclass of: inhibitor
definition: An compound that inhibits quinol oxidation sites.
id: CHEBI:74352
database_cross_reference: PMID:15312779
database_cross_reference: PMID:7961852
has_related_synonym: QP site inhibitor
has_related_synonym: QP site inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: quinol oxidation site inhibitors
in_subset: 3 STAR
imported from: chebi.owl

epidermal growth factor receptor antagonist
type: Class
subclass of: protein kinase inhibitor
subclass of: antagonist
definition: An antagonist at the epidermal growth factor receptor.
id: CHEBI:74440
has_related_synonym: EGFR antagonoist
has_related_synonym: EGFR antagonoists
has_related_synonym: EGFR inhibitor
has_related_synonym: EGFR inhibitors
database_cross_reference: Wikipedia:Epidermal_growth_factor_receptor
has_obo_namespace: chebi_ontology
has_related_synonym: epidermal growth factor receptor antagonists
has_related_synonym: epidermal growth factor receptor inhibitor
has_related_synonym: epidermal growth factor receptor inhibitors
in_subset: 3 STAR
imported from: chebi.owl

anti-obesity agent
type: Class
subclass of: pharmacological role
definition: Any substance which is used to reduce or control weight.
id: CHEBI:74518
database_cross_reference: Wikipedia:Anti-obesity
has_related_synonym: anti-obesity agents
has_related_synonym: anti-obestic agent
has_related_synonym: anti-obestic agents
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 1.1.1.44 (NADP(+)-dependent decarboxylating phosphogluconate dehydrogenase) inhibitor
type: Class
subclass of: EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor
has_related_synonym: 6-phospho-D-gluconate dehydrogenase inhibitor
has_related_synonym: 6-phospho-D-gluconate dehydrogenase inhibitors
has_related_synonym: 6-phospho-D-gluconate:NADP+ 2-oxidoreductase (decarboxylating) inhibitor
has_related_synonym: 6-phospho-D-gluconate:NADP+ 2-oxidoreductase (decarboxylating) inhibitors
has_related_synonym: 6-phosphogluconate dehydrogenase (decarboxylating) inhibitor
has_related_synonym: 6-phosphogluconate dehydrogenase (decarboxylating) inhibitors
has_related_synonym: 6-phosphogluconic carboxylase inhibitor
has_related_synonym: 6-phosphogluconic carboxylase inhibitors
has_related_synonym: 6-phosphogluconic dehydrogenase inhibitor
has_related_synonym: 6-phosphogluconic dehydrogenase inhibitors
definition: An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of NADP(+)-dependent decarboxylating phosphogluconate dehydrogenase (EC 1.1.1.44).
id: CHEBI:74520
has_related_synonym: EC 1.1.1.44 (NADP(+)-dependent decarboxylating phosphogluconate dehydrogenase) inhibitors
has_related_synonym: EC 1.1.1.44 inhibitor
has_related_synonym: EC 1.1.1.44 inhibitors
has_related_synonym: NADP(+)-dependent decarboxylating phosphogluconate dehydrogenase (EC 1.1.1.44) inhibitor
has_related_synonym: NADP(+)-dependent decarboxylating phosphogluconate dehydrogenase (EC 1.1.1.44) inhibitors
has_related_synonym: NADP(+)-dependent decarboxylating phosphogluconate dehydrogenase inhibitor
has_related_synonym: NADP(+)-dependent decarboxylating phosphogluconate dehydrogenase inhibitors
database_cross_reference: Wikipedia:Phosphogluconate_dehydrogenase_(decarboxylating)
has_obo_namespace: chebi_ontology
has_related_synonym: phosphogluconate dehydrogenase (NADP+ -dependent, decarboxylating) inhibitor
has_related_synonym: phosphogluconate dehydrogenase (NADP+ -dependent, decarboxylating) inhibitors
has_related_synonym: phosphogluconic acid dehydrogenase inhibitor
has_related_synonym: phosphogluconic acid dehydrogenase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

antidote to paracetamol poisoning
type: Class
subclass of: antidote
definition: A role borne by a molecule that acts to counteract or neutralize the deleterious effects of paracetamol (acetaminophen).
id: CHEBI:74529
database_cross_reference: PMID:16354242
database_cross_reference: PMID:16573399
database_cross_reference: PMID:16575097
database_cross_reference: PMID:22348679
database_cross_reference: PMID:22352734
database_cross_reference: PMID:22353666
database_cross_reference: PMID:22835053
database_cross_reference: PMID:22998987
database_cross_reference: PMID:7112203
has_related_synonym: Tylenol poisoning antidote
has_related_synonym: Tylenol poisoning antidotes
has_related_synonym: acetaminophen poisoning antidote
has_related_synonym: acetaminophen poisoning antidotes
has_related_synonym: antidote to Tylenol poisoning
has_related_synonym: antidote to acetaminophen poisoning
has_related_synonym: antidotes to Tylenol poisoning
has_related_synonym: antidotes to acetaminophen poisoning
has_related_synonym: antidotes to paracetamol poisoning
has_obo_namespace: chebi_ontology
has_related_synonym: paracetamol poisoning antidote
has_related_synonym: paracetamol poisoning antidotes
in_subset: 3 STAR
imported from: chebi.owl

antidote to curare poisoning
type: Class
subclass of: antidote
definition: A role borne by a molecule that acts to counteract or neutralize the deleterious effects of curare.
id: CHEBI:74530
database_cross_reference: PMID:13358565
database_cross_reference: PMID:13386996
database_cross_reference: PMID:14128111
database_cross_reference: PMID:1579914
database_cross_reference: PMID:3896015
database_cross_reference: PMID:5333582
database_cross_reference: PMID:5352084
database_cross_reference: PMID:7720787
has_related_synonym: antidote to curare
has_related_synonym: antidote to tubocurarine
has_related_synonym: antidote to tubocurarine poisoning
has_related_synonym: antidotes to curare
has_related_synonym: antidotes to curare poisoning
has_related_synonym: antidotes to tubocurarine
has_related_synonym: antidotes to tubocurarine poisoning
has_obo_namespace: chebi_ontology
has_related_synonym: curare antidote
has_related_synonym: curare antidotes
has_related_synonym: curare poisoning antidote
has_related_synonym: curare poisoning antidotes
has_related_synonym: tubocurarine antidote
has_related_synonym: tubocurarine antidotes
in_subset: 3 STAR
imported from: chebi.owl

EC 2.3.2.2 (gamma-glutamyltransferase) inhibitor
type: Class
subclass of: EC 2.3.2.* (aminoacyltransferase) inhibitor
has_related_synonym: (5-L-glutamyl)-peptide:amino-acid 5-glutamyltransferase inhibitor
has_related_synonym: (5-L-glutamyl)-peptide:amino-acid 5-glutamyltransferase inhibitors
definition: An EC 2.3.2.* (aminoacyltransferase) inhibitor that interferes with the action of gamma-glutamyltransferase (EC 2.3.2.2).
id: CHEBI:74570
has_related_synonym: EC 2.3.2.2 (gamma-glutamyltransferase) inhibitors
has_related_synonym: EC 2.3.2.2 inhibitor
has_related_synonym: EC 2.3.2.2 inhibitors
has_related_synonym: GGT inhibitor
has_related_synonym: GGT inhibitors
has_related_synonym: L-gamma-glutamyl transpeptidase inhibitor
has_related_synonym: L-gamma-glutamyl transpeptidase inhibitors
has_related_synonym: L-gamma-glutamyltransferase inhibitor
has_related_synonym: L-gamma-glutamyltransferase inhibitors
has_related_synonym: L-glutamyltransferase inhibitor
has_related_synonym: L-glutamyltransferase inhibitors
database_cross_reference: Wikipedia:Gamma-glutamyl_transpeptidase
has_related_synonym: alpha-glutamyl transpeptidase inhibitor
has_related_synonym: alpha-glutamyl transpeptidase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: gamma-GPT inhibitor
has_related_synonym: gamma-GPT inhibitors
has_related_synonym: gamma-GT inhibitor
has_related_synonym: gamma-GT inhibitors
has_related_synonym: gamma-GTP inhibitor
has_related_synonym: gamma-GTP inhibitors
has_related_synonym: gamma-glutamyl peptidyltransferase inhibitor
has_related_synonym: gamma-glutamyl peptidyltransferase inhibitors
has_related_synonym: gamma-glutamyl transpeptidase inhibitor
has_related_synonym: gamma-glutamyl transpeptidase inhibitors
has_related_synonym: gamma-glutamyltransferase (EC 2.3.2.2) inhibitor
has_related_synonym: gamma-glutamyltransferase (EC 2.3.2.2) inhibitors
has_related_synonym: gamma-glutamyltransferase inhibitor
has_related_synonym: gamma-glutamyltransferase inhibitors
has_related_synonym: gamma-glutamyltranspeptidase inhibitor
has_related_synonym: gamma-glutamyltranspeptidase inhibitors
has_related_synonym: glutamyl transpeptidase inhibitor
has_related_synonym: glutamyl transpeptidase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

astringent
type: Class
subclass of: drug
definition: A compound that causes the contraction of body tissues, typically used to reduce bleeding from minor abrasions.
id: CHEBI:74783
database_cross_reference: Wikipedia:Astringent
has_related_synonym: adstringent
has_related_synonym: adstringents
has_related_synonym: astringents
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

neoglycolipid probe
type: Class
subclass of: application
definition: A compound used as a probe during microarray analysis of oligosaccharide-protein interactions.
id: CHEBI:74886
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

microarray analysis reagent
type: Class
subclass of: reagent
definition: A reagent used in the immobilization of compounds prior to their use in microarray analysis.
id: CHEBI:74914
has_obo_namespace: chebi_ontology
has_related_synonym: microarray analysis reagents
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.23.46 (memapsin 2) inhibitor
type: Class
subclass of: EC 3.4.23.* (aspartic endopeptidase) inhibitor
definition: An EC 3.4.23.* (aspartic endopeptidase) inhibitor that interferes with the activity of memapsin 2 (EC 3.4.23.46).
has_related_synonym: BACE1 inhibitor
has_related_synonym: BACE1 inhibitors
id: CHEBI:74925
has_related_synonym: EC 3.4.23.46 (memapsin 2) inhibitors
has_related_synonym: EC 3.4.23.46 inhibitor
has_related_synonym: EC 3.4.23.46 inhibitors
has_related_synonym: Gamma-secretase inhibitor
has_related_synonym: Gamma-secretase inhibitors
database_cross_reference: Wikipedia:Gamma_secretase
has_related_synonym: beta-secretase inhibitor
has_related_synonym: beta-secretase inhibitors
has_related_synonym: beta-site APP-cleaving enzyme 1 inhibitor
has_related_synonym: beta-site APP-cleaving enzyme 1 inhibitors
has_related_synonym: beta-site Alzheimer's amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor
has_related_synonym: beta-site Alzheimer's amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors
has_related_synonym: beta-site Alzheimer's amyloid precursor protein cleaving enzyme 1 inhibitor
has_related_synonym: beta-site Alzheimer's amyloid precursor protein cleaving enzyme 1 inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: gamma-secretase inhibitor
has_related_synonym: gamma-secretase inhibitors
has_related_synonym: memapsin 2 (EC 3.4.23.46) inhibitor
has_related_synonym: memapsin 2 (EC 3.4.23.46) inhibitors
has_related_synonym: memapsin 2 inhibitor
has_related_synonym: memapsin 2 inhibitors
has_related_synonym: membrane-associated aspartic protease 2 inhibitor
has_related_synonym: membrane-associated aspartic protease 2 inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.1.27.3 (ribonuclease T1) inhibitor
type: Class
subclass of: EC 3.1.27.* (endoribonucleases producing other than 5'-phosphomonoesters) inhibitor
definition: An EC 3.1.27.* (endoribonucleases producing other than 5'-phosphomonoesters) inhibitor that interferes with the action of ribonuclease T1 (EC 3.1.27.3).
has_related_synonym: Aspergillus oryzae ribonuclease inhibitor
has_related_synonym: Aspergillus oryzae ribonuclease inhibitors
id: CHEBI:74949
has_related_synonym: EC 3.1.27.3 (ribonuclease T1) inhibitors
has_related_synonym: EC 3.1.27.3 inhibitor
has_related_synonym: EC 3.1.27.3 inhibitors
has_related_synonym: RNase F1 inhibitor
has_related_synonym: RNase F1 inhibitors
has_related_synonym: RNase G inhibitor
has_related_synonym: RNase G inhibitors
has_related_synonym: RNase N1 inhibitor
has_related_synonym: RNase N1 inhibitors
has_related_synonym: RNase N2 inhibitor
has_related_synonym: RNase N2 inhibitors
has_related_synonym: RNase Sa inhibitor
has_related_synonym: RNase Sa inhibitors
has_related_synonym: RNase T1 inhibitor
has_related_synonym: RNase T1 inhibitors
has_related_synonym: T1 inhibitor
has_related_synonym: T1 inhibitors
has_related_synonym: binase inhibitor
has_related_synonym: binase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: guanyl-specific RNase inhibitor
has_related_synonym: guanyl-specific RNase inhibitors
has_related_synonym: guanyloribonuclease inhibitor
has_related_synonym: guanyloribonuclease inhibitors
has_related_synonym: ribonuclease C2 inhibitor
has_related_synonym: ribonuclease C2 inhibitors
has_related_synonym: ribonuclease Ch inhibitor
has_related_synonym: ribonuclease Ch inhibitors
has_related_synonym: ribonuclease F1 inhibitor
has_related_synonym: ribonuclease F1 inhibitors
has_related_synonym: ribonuclease N1 inhibitor
has_related_synonym: ribonuclease N1 inhibitors
has_related_synonym: ribonuclease N3 inhibitor
has_related_synonym: ribonuclease N3 inhibitors
has_related_synonym: ribonuclease PP1 inhibitor
has_related_synonym: ribonuclease PP1 inhibitors
has_related_synonym: ribonuclease SA inhibitor
has_related_synonym: ribonuclease SA inhibitors
has_related_synonym: ribonuclease T1 (EC 3.1.27.3) inhibitor
has_related_synonym: ribonuclease T1 (EC 3.1.27.3) inhibitors
has_related_synonym: ribonuclease T1 inhibitor
has_related_synonym: ribonuclease T1 inhibitors
has_related_synonym: ribonuclease U1 inhibitor
has_related_synonym: ribonuclease U1 inhibitors
has_related_synonym: ribonuclease guaninenucleotido-2'-transferase (cyclising) inhibitor
has_related_synonym: ribonuclease guaninenucleotido-2'-transferase (cyclising) inhibitors
has_related_synonym: ribonuclease guaninenucleotido-2'-transferase (cyclizing) inhibitor
has_related_synonym: ribonuclease guaninenucleotido-2'-transferase (cyclizing) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

B-Raf inhibitor
type: Class
subclass of: EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor
definition: A serine/threonine kinase inhibitor that specifically inhibits human mutant serine/threonine kinase (B-Raf)
has_related_synonym: B-Raf inhibitors
has_related_synonym: BRAF inhibitor
has_related_synonym: BRAF inhibitors
id: CHEBI:75047
has_obo_namespace: chebi_ontology
has_related_synonym: human mutant serine/threonine kinase inhibitor
has_related_synonym: human mutant serine/threonine kinase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

chromogenic compound
type: Class
subclass of: one-colour indicator
id: CHEBI:75050
definition: Colourless, endogenous or exogenous pigment precursors that may be transformed by biological mechanisms into coloured compounds. They are used in biochemical assays and in diagnosis as indicators, particularly in the form of enzyme substrates.
has_obo_namespace: chebi_ontology
has_related_synonym: chromogen
has_related_synonym: chromogenic compounds
has_related_synonym: chromogens
in_subset: 3 STAR
imported from: chebi.owl

EC 2.5.1.21 (squalene synthase) inhibitor
type: Class
subclass of: EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor
definition: An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of squalene synthase (EC 2.5.1.21).
id: CHEBI:75174
has_related_synonym: EC 2.5.1.21 (squalene synthase) inhibitors
has_related_synonym: EC 2.5.1.21 inhibitor
has_related_synonym: EC 2.5.1.21 inhibitors
has_related_synonym: SQS inhibitor
has_related_synonym: SQS inhibitors
database_cross_reference: Wikipedia:Squalene_synthase
has_obo_namespace: chebi_ontology
has_related_synonym: farnesyl-diphosphate farnesyltransferase inhibitor
has_related_synonym: farnesyl-diphosphate farnesyltransferase inhibitors
has_related_synonym: farnesyl-diphosphate:farnesyl-diphosphate farnesyltransferase inhibitor
has_related_synonym: farnesyl-diphosphate:farnesyl-diphosphate farnesyltransferase inhibitors
has_related_synonym: farnesyltransferase inhibitor
has_related_synonym: farnesyltransferase inhibitors
has_related_synonym: presqualene synthase inhibitor
has_related_synonym: presqualene synthase inhibitors
has_related_synonym: presqualene-diphosphate synthase inhibitor
has_related_synonym: presqualene-diphosphate synthase inhibitors
has_related_synonym: squalene synthase (EC 2.5.1.21) inhibitor
has_related_synonym: squalene synthase (EC 2.5.1.21) inhibitors
has_related_synonym: squalene synthase inhibitor
has_related_synonym: squalene synthase inhibitors
has_related_synonym: squalene synthetase inhibitor
has_related_synonym: squalene synthetase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 5.4.3.2 (lysine 2,3-aminomutase) inhibitor
type: Class
subclass of: EC 5.4.3.* (intramolecular transferase transferring amino groups) inhibitor
definition: An EC 5.4.3.* (intramolecular transferase transferring amino groups) inhibitor that interferes with the action of lysine 2,3-aminomutase (EC 5.4.3.2).
id: CHEBI:75190
has_related_synonym: EC 5.4.3.2 (lysine 2,3-aminomutase) inhibitors
has_related_synonym: EC 5.4.3.2 inhibitor
has_related_synonym: EC 5.4.3.2 inhibitors
has_related_synonym: L-lysine 2,3-aminomutase inhibitor
has_related_synonym: L-lysine 2,3-aminomutase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: lysine 2,3-aminomutase (EC 5.4.3.2) inhibitor
has_related_synonym: lysine 2,3-aminomutase (EC 5.4.3.2) inhibitors
has_related_synonym: lysine 2,3-aminomutase inhibitor
has_related_synonym: lysine 2,3-aminomutase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

insulin-like growth factor receptor 1 antagonist
type: Class
subclass of: antagonist
definition: An antagonist at the insulin-like growth factor receptor 1.
id: CHEBI:75252
has_related_synonym: IGF-1R antagonist
has_related_synonym: IGF-1R antagonists
database_cross_reference: Wikipedia:Insulin-like_growth_factor_1_receptor
has_obo_namespace: chebi_ontology
has_related_synonym: insulin-like growth factor receptor 1 antagonists
in_subset: 3 STAR
imported from: chebi.owl

ergosterol biosynthesis inhibitor
type: Class
subclass of: sterol biosynthesis inhibitor
definition: Any compound that inhibits one or more steps in the pathway leading to the synthesis of ergosterol.
id: CHEBI:75282
database_cross_reference: PMID:12604527
database_cross_reference: PMID:19835945
has_obo_namespace: chebi_ontology
has_related_synonym: ergosterol biosynthesis inhibitors
in_subset: 3 STAR
imported from: chebi.owl

histamine releasing agent
type: Class
subclass of: biochemical role
definition: Any substance that can induce the release of histamine from mast cells.
id: CHEBI:75298
has_obo_namespace: chebi_ontology
has_related_synonym: histamine releasing agents
has_related_synonym: histamine releasing compound
has_related_synonym: histamine releasing compounds
has_related_synonym: histamine releasing substance
has_related_synonym: histamine releasing substances
in_subset: 3 STAR
imported from: chebi.owl

excipient
type: Class
subclass of: application
definition: A generally pharmacologically inactive substance that is formulated with the active ingredient of a medication.
id: CHEBI:75324
database_cross_reference: PMID:19709488
database_cross_reference: PMID:21086329
database_cross_reference: PMID:22707004
database_cross_reference: PMID:22877709
database_cross_reference: PMID:23450581
database_cross_reference: PMID:23525964
database_cross_reference: PMID:23657359
database_cross_reference: Wikipedia:Excipient
has_related_synonym: bulking agent
has_related_synonym: bulking agents
has_obo_namespace: chebi_ontology
has_exact_synonym: excipient
has_related_synonym: filler
has_related_synonym: fillers
in_subset: 3 STAR
imported from: chebi.owl

cathartic
type: Class
subclass of: biophysical role
definition: Any substance that accelerates defecation. Compare with laxatives, which are substances that ease defecation (usually by softening faeces). A substance can be both a laxative and a cathartic.
id: CHEBI:75325
database_cross_reference: Wikipedia:Cathartic
has_related_synonym: cathartics
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

curing agent
type: Class
subclass of: application
definition: A chemical additive used to toughen or harden a polymer material by cross-linking of polymer chains.
id: CHEBI:75358
has_obo_namespace: chebi_ontology
has_related_synonym: curing agents
has_related_synonym: vulcanization agent
has_related_synonym: vulcanization agents
has_related_synonym: vulcanizing agent
has_related_synonym: vulcanizing agents
in_subset: 3 STAR
imported from: chebi.owl

EC 1.11.1.6 (catalase) inhibitor
type: Class
subclass of: EC 1.11.1.* (peroxidases) inhibitor
definition: An inhibitor of peroxidases (EC 1.11.1.*) that inhibits the action of catalase (EC 1.11.1.6).
has_related_synonym: CAT inhibitor
has_related_synonym: CAT inhibitors
id: CHEBI:75380
has_related_synonym: EC 1.11.1.6 (catalase) inhibitors
has_related_synonym: EC 1.11.1.6 inhibitor
has_related_synonym: EC 1.11.1.6 inhibitors
has_related_synonym: caperase inhibitor
has_related_synonym: caperase inhibitors
has_related_synonym: catalase (EC 1.11.1.6) inhibitor
has_related_synonym: catalase (EC 1.11.1.6) inhibitors
has_related_synonym: catalase inhibitor
has_related_synonym: catalase inhibitors
has_related_synonym: catalase-peroxidase inhibitor
has_related_synonym: catalase-peroxidase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: equilase inhibitor
has_related_synonym: equilase inhibitors
has_related_synonym: hydrogen-peroxide:hydrogen-peroxide oxidoreductase inhibitor
has_related_synonym: hydrogen-peroxide:hydrogen-peroxide oxidoreductase inhibitors
has_related_synonym: optidase inhibitor
has_related_synonym: optidase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.11.1.* (peroxidases) inhibitor
type: Class
subclass of: EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitor
definition: An EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitor that interferes with the action of any of the peroxidases (EC 1.11.1.*).
id: CHEBI:75381
has_related_synonym: EC 1.11.1 inhibitor
has_related_synonym: EC 1.11.1 inhibitors
has_related_synonym: EC 1.11.1.* (peroxidase) inhibitor
has_related_synonym: EC 1.11.1.* (peroxidase) inhibitors
has_related_synonym: EC 1.11.1.* (peroxidases) inhibitors
has_related_synonym: EC 1.11.1.* inhibitor
has_related_synonym: EC 1.11.1.* inhibitors
database_cross_reference: Wikipedia:Peroxidases
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of peroxidases
has_related_synonym: inhibitors of peroxidases
has_related_synonym: peroxidases inhibitors
in_subset: 3 STAR
imported from: chebi.owl

platelet-activating factor receptor agonist
type: Class
subclass of: agonist
definition: An agonist that binds to and activates platelet-activating factor receptors.
id: CHEBI:75414
database_cross_reference: Wikipedia:Platelet-activating_factor_receptor
has_obo_namespace: chebi_ontology
has_related_synonym: platelet-activating factor receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

EC 6.1.1.* (ligases forming aminoacyl tRNA and related compounds) inhibitor
type: Class
subclass of: EC 6.1.* (C-O bond-forming ligase) inhibitor
definition: An EC 6.1.* (C-O bond-forming ligase) inhibitor that interferes with the action of any ligase forming aminoacyl tRNA and related compounds (EC 6.1.1.*).
id: CHEBI:75416
has_related_synonym: EC 6.1.1.* (ligases forming aminoacyl tRNA and related compounds) inhibitors
has_related_synonym: EC 6.1.1.* inhibitor
has_related_synonym: EC 6.1.1.* inhibitors
has_related_synonym: aminoacyl tRNA synthetase inhibitor
has_related_synonym: aminoacyl tRNA synthetase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: ligases forming aminoacyl tRNA and related compounds (EC 6.1.1.*) inhibitor
has_related_synonym: ligases forming aminoacyl tRNA and related compounds (EC 6.1.1.*) inhibitors
has_related_synonym: tRNA synthetase inhibitor
has_related_synonym: tRNA synthetase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.4.4.2 [glycine dehydrogenase (aminomethyl-transferring)] inhibitor
type: Class
subclass of: EC 1.4.4.* (oxidoreductase acting on donor CH-NH2 group, a disulfide as acceptor) inhibitor
definition: An EC 1.4.4.* (oxidoreductase acting on donor CH-NH2 group, a disulfide as acceptor) inhibitor that interferes with the action of glycine decarboxylase (EC 1.4.4.2).
id: CHEBI:75429
has_related_synonym: EC 1.4.4.2 (glycine dehydrogenase (aminomethyl-transferring)) inhibitor
has_related_synonym: EC 1.4.4.2 (glycine dehydrogenase (aminomethyl-transferring)) inhibitors
has_related_synonym: EC 1.4.4.2 [glycine dehydrogenase (aminomethyl-transferring)] inhibitors
has_related_synonym: EC 1.4.4.2 inhibitor
has_related_synonym: EC 1.4.4.2 inhibitors
has_related_synonym: P-protein inhibitor
has_related_synonym: P-protein inhibitors
database_cross_reference: Wikipedia:Glycine_cleavage_system
has_obo_namespace: chebi_ontology
has_related_synonym: glycine cleavage system P-protein inhibitor
has_related_synonym: glycine cleavage system P-protein inhibitors
has_related_synonym: glycine decarboxylase inhibitor
has_related_synonym: glycine decarboxylase inhibitors
has_related_synonym: glycine dehydrogenase (aminomethyl-transferring) (EC 1.4.4.2) inhibitor
has_related_synonym: glycine dehydrogenase (aminomethyl-transferring) (EC 1.4.4.2) inhibitors
has_related_synonym: glycine dehydrogenase (aminomethyl-transferring) inhibitor
has_related_synonym: glycine dehydrogenase (aminomethyl-transferring) inhibitors
has_related_synonym: glycine dehydrogenase (decarboxylating) inhibitor
has_related_synonym: glycine dehydrogenase (decarboxylating) inhibitors
has_related_synonym: glycine-cleavage complex P-protein inhibitor
has_related_synonym: glycine-cleavage complex P-protein inhibitors
has_related_synonym: glycine-cleavage complex inhibitor
has_related_synonym: glycine-cleavage complex inhibitors
has_related_synonym: glycine:H-protein-lipoyllysine oxidoreductase (decarboxylating, acceptor-amino-methylating)
has_related_synonym: glycine:H-protein-lipoyllysine oxidoreductase (decarboxylating, acceptor-amino-methylating) inhibitor
has_related_synonym: glycine:lipoylprotein oxidoreductase (decarboxylating and acceptor-aminomethylating) inhibitor
has_related_synonym: glycine:lipoylprotein oxidoreductase (decarboxylating and acceptor-aminomethylating) inhibitors
has_related_synonym: protein P1 inhibitor
has_related_synonym: protein P1 inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 6.1.1.11 (serine--tRNA ligase) inhibitor
type: Class
subclass of: EC 6.1.1.* (ligases forming aminoacyl tRNA and related compounds) inhibitor
definition: An EC 6.1.1.* (ligases forming aminoacyl tRNA and related compounds) inhibitor that specifically inhibits the action of seryl-tRNA synthetase (EC 6.1.1.11).
id: CHEBI:75495
has_exact_synonym: EC 6.1.1.11 (serine--tRNA ligase) inhibitor
has_related_synonym: EC 6.1.1.11 (serine--tRNA ligase) inhibitors
has_related_synonym: EC 6.1.1.11 inhibitor
has_related_synonym: EC 6.1.1.11 inhibitors
has_related_synonym: L-serine:tRNA(Ser) ligase (AMP-forming) inhibitor
has_related_synonym: L-serine:tRNA(Ser) ligase (AMP-forming) inhibitors
has_related_synonym: SerRS inhibitor
has_related_synonym: SerRS inhibitors
database_cross_reference: Wikipedia:Serine-tRNA_ligase
has_obo_namespace: chebi_ontology
has_related_synonym: serine translase inhibitor
has_related_synonym: serine translase inhibitors
has_related_synonym: serine--tRNA ligase (EC 6.1.1.11) inhibitor
has_related_synonym: serine--tRNA ligase (EC 6.1.1.11) inhibitors
has_related_synonym: serine--tRNA ligase inhibitor
has_related_synonym: serine--tRNA ligase inhibitors
has_related_synonym: seryl-tRNA synthetase inhibitor
has_related_synonym: seryl-tRNA synthetase inhibitors
has_related_synonym: seryl-transfer RNA synthetase inhibitor
has_related_synonym: seryl-transfer RNA synthetase inhibitors
has_related_synonym: seryl-transfer ribonucleate synthetase inhibitor
has_related_synonym: seryl-transfer ribonucleate synthetase inhibitors
has_related_synonym: seryl-transfer ribonucleic acid synthetase inhibitor
has_related_synonym: seryl-transfer ribonucleic acid synthetase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 5.1.1.1 (alanine racemase) inhibitor
type: Class
subclass of: EC 5.1.1.* (racemases acting on amino acids and derivatives) inhibitor
definition: An EC 5.1.1.* (racemases acting on amino acids and derivatives) inhibitor that interferes with the action of alanine racemase (EC 5.1.1.1).
id: CHEBI:75595
has_related_synonym: EC 5.1.1.1 (alanine racemase) inhibitors
has_related_synonym: EC 5.1.1.1 inhibitor
has_related_synonym: EC 5.1.1.1 inhibitors
has_related_synonym: L-alanine racemase inhibitor
has_related_synonym: L-alanine racemase inhibitors
database_cross_reference: Wikipedia:Alanine_racemase
has_related_synonym: alanine racemase (EC 5.1.1.1) inhibitor
has_related_synonym: alanine racemase (EC 5.1.1.1) inhibitors
has_related_synonym: alanine racemase inhibitor
has_related_synonym: alanine racemase inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 5.* (isomerase) inhibitor
type: Class
subclass of: enzyme inhibitor
definition: An enzyme inhibitor that inhibits the action of an isomerase (EC 5.*.*.*).
id: CHEBI:75596
has_related_synonym: EC 5.* (isomerase) inhibitors
has_related_synonym: EC 5.* inhibitor
has_related_synonym: EC 5.* inhibitors
has_related_synonym: EC 5.*.*.* inhibitor
has_related_synonym: EC 5.*.*.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: isomerase (EC 5.*) inhibitor
has_related_synonym: isomerase (EC 5.*) inhibitors
has_related_synonym: isomerase inhibitor
has_related_synonym: isomerase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 6.3.2.4 (D-alanine--D-alanine ligase) inhibitor
type: Class
subclass of: EC 6.3.2.* (acid--D-amino-acid ligase) inhibitor
definition: An acid--amino-acid ligase inhibitor that inhibits the action of a D-alanine--D-alanine ligase (EC 6.3.2.4).
id: CHEBI:75598
has_related_synonym: D-alanine--D-alanine ligase (EC 6.3.2.4) inhibitor
has_related_synonym: D-alanine--D-alanine ligase (EC 6.3.2.4) inhibitors
has_related_synonym: D-alanine--D-alanine ligase inhibitor
has_related_synonym: D-alanine--D-alanine ligase inhibitors
has_related_synonym: D-alanine:D-alanine ligase (ADP-forming) inhibitor
has_related_synonym: D-alanine:D-alanine ligase (ADP-forming) inhibitors
has_related_synonym: EC 6.3.2.4 (D-alanine--D-alanine ligase) inhibitors
has_related_synonym: EC 6.3.2.4 inhibitor
has_related_synonym: EC 6.3.2.4 inhibitors
database_cross_reference: Wikipedia:D-alanine_ligase
has_related_synonym: alanine:alanine ligase (ADP-forming) inhibitor
has_related_synonym: alanine:alanine ligase (ADP-forming) inhibitors
has_related_synonym: alanylalanine synthetase inhibitor
has_related_synonym: alanylalanine synthetase inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 6.3.2.2 (glutamate--cysteine ligase) inhibitor
type: Class
subclass of: EC 6.3.2.* (acid--D-amino-acid ligase) inhibitor
definition: An acid--amino-acid ligase inhibitor that inhibits the action of a glutamate--cysteine ligase (EC 6.3.2.2)
id: CHEBI:75599
has_related_synonym: EC 6.3.2.2 (glutamate--cysteine ligase) inhibitors
has_related_synonym: EC 6.3.2.2 inhibitor
has_related_synonym: EC 6.3.2.2 inhibitors
database_cross_reference: Wikipedia:Glutamate-cysteine_ligase
has_obo_namespace: chebi_ontology
has_related_synonym: gamma-glutamyl-L-cysteine synthetase inhibitor
has_related_synonym: gamma-glutamyl-L-cysteine synthetase inhibitors
has_related_synonym: gamma-glutamylcysteine synthetase inhibitor
has_related_synonym: gamma-glutamylcysteine synthetase inhibitors
has_related_synonym: gamma-glutamylcysteinyl synthetase inhibitor
has_related_synonym: gamma-glutamylcysteinyl synthetase inhibitors
has_related_synonym: glutamate--cysteine ligase (EC 6.3.2.2) inhibitor
has_related_synonym: glutamate--cysteine ligase (EC 6.3.2.2) inhibitors
has_related_synonym: glutamate--cysteine ligase inhibitor
has_related_synonym: glutamate--cysteine ligase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 6.3.* (C-N bond-forming ligase) inhibitor
type: Class
subclass of: EC 6.* (ligase) inhibitor
definition: A ligase inhibitor that interferes with the action of a C-N bond-forming ligase (EC 6.3.*.*).
has_related_synonym: C--N bond-forming ligase inhibitor
has_related_synonym: C--N bond-forming ligase inhibitors
has_related_synonym: C-N bond-forming ligase (EC 6.3.*) inhibitor
has_related_synonym: C-N bond-forming ligase (EC 6.3.*) inhibitors
has_related_synonym: C-N bond-forming ligase inhibitor
has_related_synonym: C-N bond-forming ligase inhibitors
id: CHEBI:75600
has_related_synonym: EC 6.3.* (C-N bond-forming ligase) inhibitorS
has_related_synonym: EC 6.3.* inhibitor
has_related_synonym: EC 6.3.* inhibitors
has_related_synonym: EC 6.3.*.* inhibitor
has_related_synonym: EC 6.3.*.* inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 6.* (ligase) inhibitor
type: Class
subclass of: enzyme inhibitor
definition: Any enzyme inhibitor that interferes with the action of a ligase (EC 6.*.*.*). Ligases are enzymes that catalyse the joining of two molecules with concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
id: CHEBI:75603
has_related_synonym: EC 6.* (ligase) inhibitors
has_related_synonym: EC 6.* inhibitor
has_related_synonym: EC 6.* inhibitors
has_related_synonym: EC 6.*.*.* inhibitor
has_related_synonym: EC 6.*.*.* inhibitors
database_cross_reference: Wikipedia:Ligase
has_obo_namespace: chebi_ontology
has_related_synonym: ligase inhibitor
has_related_synonym: ligase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 6.4.* (C-C bond-forming ligase) inhibitor
type: Class
subclass of: EC 6.* (ligase) inhibitor
definition: A ligase inhibitor that interferes with the action of a C-C bond-forming ligase (EC 6.4.*.*).
has_related_synonym: C--C bond-forming ligase inhibitor
has_related_synonym: C--C bond-forming ligase inhibitors
has_related_synonym: C-C bond-forming ligase (EC 6.4.*) inhibitor
has_related_synonym: C-C bond-forming ligase (EC 6.4.*) inhibitorS
has_related_synonym: C-C bond-forming ligase inhibitor
has_related_synonym: C-C bond-forming ligase inhibitors
id: CHEBI:75604
has_related_synonym: EC 6.4.* (C-C bond-forming ligase) inhibitorS
has_related_synonym: EC 6.4.* inhibitor
has_related_synonym: EC 6.4.* inhibitors
has_related_synonym: EC 6.4.*.* inhibitor
has_related_synonym: EC 6.4.*.* inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 6.5.* (phosphoric ester bond-forming ligase) inhibitor
type: Class
subclass of: EC 6.* (ligase) inhibitor
definition: A ligase inhibitor which inhibits the action of a phosphoric ester bond-forming ligase (EC 6.5.*.*).
id: CHEBI:75605
has_related_synonym: EC 6.5.* (phosphoric ester bond-forming ligase) inhibitors
has_related_synonym: EC 6.5.* inhibitor
has_related_synonym: EC 6.5.* inhibitors
has_related_synonym: EC 6.5.*.* inhibitor
has_related_synonym: EC 6.5.*.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: phosphoric ester bond-forming ligase (EC 6.5.*) inhibitor
has_related_synonym: phosphoric ester bond-forming ligase (EC 6.5.*) inhibitors
has_related_synonym: phosphoric ester bond-forming ligase inhibitor
has_related_synonym: phosphoric ester bond-forming ligase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

nifedipine
type: Class
subclass of: molecular entity
charge: 0
monoisotopicmass: 346.11649
mass: 346.33460
has_related_synonym: 4-(2'-Nitrophenyl)-2,6-dimethyl-1,4-dihydropyridin-3,5-dicarbonsaeuredimethylester
has_related_synonym: Adalat
has_related_synonym: Adapine
database_cross_reference: Beilstein:497773
formula: C17H18N2O6
database_cross_reference: CAS:21829-25-4
id: CHEBI:7565
smiles: COC(=O)C1=C(C)NC(C)=C(C1c1ccccc1[N+]([O-])=O)C(=O)OC
has_related_synonym: Coracten
database_cross_reference: DrugBank:DB01115
database_cross_reference: Drug_Central:1922
inchikey: HYIMSNHJOBLJNT-UHFFFAOYSA-N
inchi: InChI=1S/C17H18N2O6/c1-9-13(16(20)24-3)15(14(10(2)18-9)17(21)25-4)11-7-5-6-8-12(11)19(22)23/h5-8,15,18H,1-4H3
database_cross_reference: KEGG:C07266
database_cross_reference: KEGG:D00437
database_cross_reference: LINCS:LSM-4176
has_related_synonym: Nifecard
has_related_synonym: Nifecor
has_exact_synonym: Nifedipine
has_related_synonym: Nifedipres
has_related_synonym: Procardia
database_cross_reference: Wikipedia:Nifedipine
has_obo_namespace: chebi_ontology
has_exact_synonym: dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
has_related_synonym: nifedipine
has_related_synonym: nifedipino
has_related_synonym: nifedipinum
in_subset: 3 STAR
imported from: chebi.owl

eukaryotic metabolite
type: Class
subclass of: metabolite
definition: Any metabolite produced during a metabolic reaction in eukaryotes, the taxon that include members of the fungi, plantae and animalia kingdoms.
id: CHEBI:75763
has_obo_namespace: chebi_ontology
has_related_synonym: eukaryotic metabolites
in_subset: 3 STAR
imported from: chebi.owl

animal metabolite
type: Class
subclass of: eukaryotic metabolite
definition: Any eukaryotic metabolite produced during a metabolic reaction in animals that include diverse creatures from sponges, insects to mammals.
id: CHEBI:75767
has_alternative_id: CHEBI:77721
has_alternative_id: CHEBI:77743
has_related_synonym: animal metabolites
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

mammalian metabolite
type: Class
subclass of: animal metabolite
definition: Any animal metabolite produced during a metabolic reaction in mammals.
id: CHEBI:75768
has_alternative_id: CHEBI:77464
has_alternative_id: CHEBI:77744
has_obo_namespace: chebi_ontology
has_related_synonym: mammalian metabolites
in_subset: 3 STAR
imported from: chebi.owl

mouse metabolite
type: Class
subclass of: mammalian metabolite
definition: Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
id: CHEBI:75771
has_related_synonym: Mus musculus metabolite
has_related_synonym: Mus musculus metabolites
has_obo_namespace: chebi_ontology
has_related_synonym: mouse metabolites
in_subset: 3 STAR
imported from: chebi.owl

Saccharomyces cerevisiae metabolite
type: Class
subclass of: fungal metabolite
definition: Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae).
id: CHEBI:75772
has_alternative_id: CHEBI:76949
has_alternative_id: CHEBI:76951
has_related_synonym: S. cerevisiae metabolite
has_related_synonym: S. cerevisiae metabolites
has_related_synonym: S. cerevisiae secondary metabolite
has_related_synonym: S. cerevisiae secondary metabolites
has_related_synonym: Saccharomyces cerevisiae metabolites
has_related_synonym: Saccharomyces cerevisiae secondary metabolites
has_related_synonym: baker's yeast metabolite
has_related_synonym: baker's yeast metabolites
has_related_synonym: baker's yeast secondary metabolite
has_related_synonym: baker's yeast secondary metabolites
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

prokaryotic metabolite
type: Class
subclass of: metabolite
definition: Any metabolite produced during a metabolic reaction in prokaryotes, the taxon that include members of domains such as the bacteria and archaea.
id: CHEBI:75787
has_obo_namespace: chebi_ontology
has_related_synonym: prokaryotic metabolites
in_subset: 3 STAR
imported from: chebi.owl

anti-anaemic agent
type: Class
subclass of: application
definition: A compound which increases either the number of red cells or the amount of haemoglobin in the blood.
id: CHEBI:75835
has_related_synonym: anti-anaemic agents
has_related_synonym: anti-anaemic drug
has_related_synonym: anti-anaemic drugs
has_related_synonym: anti-anemia agent
has_related_synonym: anti-anemia agents
has_related_synonym: anti-anemia drug
has_related_synonym: anti-anemia drugs
has_related_synonym: anti-anemic agent
has_related_synonym: anti-anemic agents
has_related_synonym: anti-anemic drug
has_related_synonym: anti-anemic drugs
has_related_synonym: antianaemia agent
has_related_synonym: antianaemia agents
has_related_synonym: antianaemia drug
has_related_synonym: antianaemia drugs
has_related_synonym: antianaemic agent
has_related_synonym: antianaemic agents
has_related_synonym: antianaemic drug
has_related_synonym: antianaemic drugs
has_related_synonym: antianemia drug
has_related_synonym: antianemia drugs
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 6.3.2.19 (ubiquitin--protein ligase) inhibitor
type: Class
subclass of: EC 6.3.2.* (acid--D-amino-acid ligase) inhibitor
definition: An enzyme inhibitor that interferes with the action of ubiquitin--protein ligase (EC 6.3.2.19).
id: CHEBI:75968
has_related_synonym: EC 6.3.2.19 (ubiquitin--protein ligase) inhibitors
has_related_synonym: EC 6.3.2.19 inhibitor
has_related_synonym: EC 6.3.2.19 inhibitors
has_related_synonym: S-phase kinase-associated protein 2 inhibitor
has_related_synonym: S-phase kinase-associated protein 2 inhibitors
has_related_synonym: Skp2 inhibitor
has_related_synonym: Skp2 inhibitors
database_cross_reference: Wikipedia:Ubiquitin_ligase
has_obo_namespace: chebi_ontology
has_related_synonym: ubiquitin--protein ligase inhibitor
has_related_synonym: ubiquitin--protein ligase inhibitors
has_related_synonym: ubiquitin-activating enzyme inhibitor
has_related_synonym: ubiquitin-activating enzyme inhibitors
has_related_synonym: ubiquitin:protein-lysine N-ligase (AMP-forming) inhibitor
has_related_synonym: ubiquitin:protein-lysine N-ligase (AMP-forming) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

soluble guanylate cyclase activator
type: Class
subclass of: enzyme activator
definition: Any compound that binds to and activates soluble guanylate cyclase (EC 4.6.1.2).
id: CHEBI:76022
database_cross_reference: Wikipedia:Soluble_guanylyl_cyclase
has_obo_namespace: chebi_ontology
has_related_synonym: sGC activator
has_related_synonym: sGC activators
has_related_synonym: soluble guanylate cyclase activators
has_related_synonym: soluble guanylyl cyclase activator
has_related_synonym: soluble guanylyl cyclase activators
in_subset: 3 STAR
imported from: chebi.owl

xenobiotic metabolite
type: Class
subclass of: metabolite
definition: Any metabolite produced by metabolism of a xenobiotic compound.
id: CHEBI:76206
has_obo_namespace: chebi_ontology
has_related_synonym: xenobiotic metabolites
in_subset: 3 STAR
imported from: chebi.owl

fluorogen
type: Class
subclass of: biological role
definition: A non-fluorescent small compound which become fluorescent only when complexed to a fluorogen activating protein (FAP).
id: CHEBI:76219
database_cross_reference: PMID:22135118
database_cross_reference: PMID:22191699
database_cross_reference: PMID:23325316
database_cross_reference: PMID:23404950
database_cross_reference: PMID:23506236
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 2.3.1.48 (histone acetyltransferase) inhibitor
type: Class
subclass of: EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor
definition: An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the function of histone acetyltransferase (EC 2.3.1.48).
id: CHEBI:76395
has_related_synonym: EC 2.3.1.48 (histone acetyltransferase) inhibitors
has_related_synonym: EC 2.3.1.48 inhibitor
has_related_synonym: EC 2.3.1.48 inhibitors
has_related_synonym: HAT inhibitor
has_related_synonym: HAT inhibitors
database_cross_reference: Wikipedia:Histone_acetyltransferase
has_related_synonym: acetyl-CoA:histone acetyltransferase inhibitor
has_related_synonym: acetyl-CoA:histone acetyltransferase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: histone acetokinase inhibitor
has_related_synonym: histone acetokinase inhibitors
has_related_synonym: histone acetylase inhibitor
has_related_synonym: histone acetylase inhibitors
has_related_synonym: histone acetyltransferase (EC 2.3.1.48) inhibitor
has_related_synonym: histone acetyltransferase (EC 2.3.1.48) inhibitors
has_related_synonym: histone acetyltransferase inhibitor
has_related_synonym: histone acetyltransferase inhibitors
has_related_synonym: histone transacetylase inhibitor
has_related_synonym: histone transacetylase inhibitors
has_related_synonym: nucleosome-histone acetyltransferase inhibitor
has_related_synonym: nucleosome-histone acetyltransferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

greenhouse gas
type: Class
subclass of: chemical role
definition: A gas in an atmosphere that absorbs and emits radiation within the thermal infrared range, so contributing to the 'greenhouse effect'.
id: CHEBI:76413
database_cross_reference: Wikipedia:Greenhouse_gas
has_obo_namespace: chebi_ontology
has_related_synonym: greenhouse gases
in_subset: 3 STAR
imported from: chebi.owl

propellant
type: Class
subclass of: application
definition: A compressed gas or liquid with a boiling point lower than room temperature which to used to propel and dispense liquids such as deodorants, insecticides, paints, etc. from aerosol cans.
id: CHEBI:76414
database_cross_reference: PMID:22519407
database_cross_reference: PMID:24001847
has_obo_namespace: chebi_ontology
has_related_synonym: propellants
in_subset: 3 STAR
imported from: chebi.owl

coral metabolite
type: Class
subclass of: animal metabolite
subclass of: marine metabolite
definition: Any animal metabolite produced during a metabolic reaction in corals (marine invertebrates).
id: CHEBI:76498
has_obo_namespace: chebi_ontology
has_related_synonym: coral metabolites
in_subset: 3 STAR
imported from: chebi.owl

marine metabolite
type: Class
subclass of: metabolite
definition: Any metabolite produced during a metabolic reaction in marine macro- and microorganisms.
id: CHEBI:76507
has_alternative_id: CHEBI:77078
has_obo_namespace: chebi_ontology
has_related_synonym: marine metabolites
in_subset: 3 STAR
imported from: chebi.owl

odorant receptor antagonist
type: Class
subclass of: antagonist
definition: An antagonist at the odorant receptor.
id: CHEBI:76531
has_obo_namespace: chebi_ontology
has_related_synonym: odorant receptor antagonists
has_related_synonym: odorant receptor blocker
has_related_synonym: odorant receptor blockers
in_subset: 3 STAR
imported from: chebi.owl

nephroprotective agent
type: Class
subclass of: protective agent
definition: Any protective agent that is able to prevent damage to the kidney.
id: CHEBI:76595
has_obo_namespace: chebi_ontology
has_related_synonym: nephroprotective agents
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor
type: Class
subclass of: tyrosine kinase inhibitor
subclass of: EC 2.7.10.* (protein-tyrosine kinase) inhibitor
has_related_synonym: ABL inhibitor
has_related_synonym: ABL inhibitors
has_related_synonym: ABL1 inhibitor
has_related_synonym: ABL1 inhibitors
has_related_synonym: ABL2 inhibitor
has_related_synonym: ABL2 inhibitors
has_related_synonym: ABLL inhibitor
has_related_synonym: ABLL inhibitors
has_related_synonym: ACK1 inhibitor
has_related_synonym: ACK1 inhibitors
has_related_synonym: ACK2 inhibitor
has_related_synonym: ACK2 inhibitors
has_related_synonym: AGMX1 inhibitor
has_related_synonym: AGMX1 inhibitors
has_related_synonym: ARG inhibitor
has_related_synonym: ARG inhibitors
has_related_synonym: ATK inhibitor
has_related_synonym: ATK inhibitors
has_related_synonym: ATP:[protein]-L-tyrosine O-phosphotransferase (non-specific) inhibitor
has_related_synonym: ATP:[protein]-L-tyrosine O-phosphotransferase (non-specific) inhibitors
definition: An EC 2.7.10.* (protein-tyrosine kinase) inhibitor that specifically blocks the action of non-specific protein-tyrosine kinase (EC 2.7.10.2).
has_related_synonym: BLK inhibitor
has_related_synonym: BLK inhibitors
has_related_synonym: BMX inhibitor
has_related_synonym: BMX inhibitors
has_related_synonym: BRK inhibitor
has_related_synonym: BRK inhibitors
has_related_synonym: BTK inhibitor
has_related_synonym: BTK inhibitors
has_related_synonym: BTKL inhibitor
has_related_synonym: BTKL inhibitors
has_related_synonym: Bmk inhibitor
has_related_synonym: Bmk inhibitors
has_related_synonym: Bruton's tyrosine kinase inhibitor
has_related_synonym: Bruton's tyrosine kinase inhibitors
has_related_synonym: Bsk inhibitor
has_related_synonym: Bsk inhibitors
has_related_synonym: CAKb inhibitor
has_related_synonym: CAKb inhibitors
has_alternative_id: CHEBI:66921
id: CHEBI:76617
has_related_synonym: CHK inhibitor
has_related_synonym: CHK inhibitors
has_related_synonym: CSK inhibitor
has_related_synonym: CSK inhibitors
has_related_synonym: CTK inhibitor
has_related_synonym: CTK inhibitors
has_related_synonym: CYL inhibitor
has_related_synonym: CYL inhibitors
has_related_synonym: Cdgip inhibitor
has_related_synonym: Cdgip inhibitors
has_related_synonym: EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitors
has_related_synonym: EC 2.7.10.2 inhibitor
has_related_synonym: EC 2.7.10.2 inhibitors
has_related_synonym: EMT inhibitor
has_related_synonym: EMT inhibitors
has_related_synonym: ETK inhibitor
has_related_synonym: ETK inhibitors
has_related_synonym: FAK inhibitor
has_related_synonym: FAK inhibitors
has_related_synonym: FAK2 inhibitor
has_related_synonym: FAK2 inhibitors
has_related_synonym: FER inhibitor
has_related_synonym: FER inhibitors
has_related_synonym: FES inhibitor
has_related_synonym: FES inhibitors
has_related_synonym: FGR inhibitor
has_related_synonym: FGR inhibitors
has_related_synonym: FPS inhibitor
has_related_synonym: FPS inhibitors
has_related_synonym: FRK inhibitor
has_related_synonym: FRK inhibitors
has_related_synonym: FYN inhibitor
has_related_synonym: FYN inhibitors
has_related_synonym: Fadk inhibitor
has_related_synonym: Fadk inhibitors

fluorescence quencher
type: Class
subclass of: chemical role
definition: A compound used to return an excited fluorophore to the ground state by transfer of energy from fluorophore to quencher without the emission of light, with the quencher being promoted to its own excited state.
id: CHEBI:76648
has_obo_namespace: chebi_ontology
has_related_synonym: fluorescence quenchers
in_subset: 3 STAR
imported from: chebi.owl

EC 2.1.* (C1-transferase) inhibitor
type: Class
subclass of: EC 2.* (transferase) inhibitor
definition: A transferase inhibitor inhibiting the action of transferase of a one-carbon-containing group (EC 2.1.*.*).
has_related_synonym: C1-transferase (EC 2.1.*) inhibitor
has_related_synonym: C1-transferase (EC 2.1.*) inhibitors
has_related_synonym: C1-transferase inhibitor
has_related_synonym: C1-transferase inhibitors
id: CHEBI:76655
has_related_synonym: EC 2.1.* (C1-transferase) inhibitors
has_related_synonym: EC 2.1.* inhibitor
has_related_synonym: EC 2.1.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: one-carbon-containing group transferase inhibitor
has_related_synonym: one-carbon-containing group transferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.2.* (aldehyde or ketone transferase) inhibitor
type: Class
subclass of: EC 2.* (transferase) inhibitor
definition: A transferase inhibitor interfering with the action of any transferase that transfers an aldehyde or ketone group (EC 2.2.*.*).
id: CHEBI:76660
has_related_synonym: EC 2.2.* (aldehyde or ketone transferase) inhibitors
has_related_synonym: EC 2.2.* inhibitor
has_related_synonym: EC 2.2.* inhibitors
has_related_synonym: aldehyde or ketone transferase inhibitor
has_related_synonym: aldehyde or ketone transferase inhibitors
has_related_synonym: aldehyde/ketone transferase (EC 2.2.*) inhibitor
has_related_synonym: aldehyde/ketone transferase (EC 2.2.*) inhibitors
has_related_synonym: aldehyde/ketone transferase inhibitor
has_related_synonym: aldehyde/ketone transferase inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 2.3.* (acyltransferase) inhibitor
type: Class
subclass of: EC 2.* (transferase) inhibitor
definition: A transferase inhibitor that interferes with the action of an acyltransferase (EC 2.3.*.*).
id: CHEBI:76661
has_related_synonym: EC 2.3.* (acyltransferase) inhibitors
has_related_synonym: EC 2.3.* inhibitor
has_related_synonym: EC 2.3.* inhibitors
has_related_synonym: acyltransferase inhibitor
has_related_synonym: acyltransferase inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 2.4.* (glycosyltransferase) inhibitor
type: Class
subclass of: EC 2.* (transferase) inhibitor
definition: A transferase inhibitor inhibiting the action of a glycosyltransferase (EC 2.4.*.*).
id: CHEBI:76662
has_related_synonym: EC 2.4.* (glycosyltransferase) inhibitors
has_related_synonym: EC 2.4.* inhibitor
has_related_synonym: EC 2.4.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: glycosyltransferase (EC 2.4.*) inhibitor
has_related_synonym: glycosyltransferase (EC 2.4.*) inhibitors
has_related_synonym: glycosyltransferase inhibitor
has_related_synonym: glycosyltransferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor
type: Class
subclass of: EC 2.5.* (non-methyl-alkyl or aryl transferase) inhibitor
definition: A transferase inhibitor that inhibits the transfer of an alkyl (other than methyl) or aryl group (EC 2.5.1.*).
id: CHEBI:76663
has_related_synonym: EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitors
has_related_synonym: EC 2.5.1.* inhibitor
has_related_synonym: EC 2.5.1.* inhibitors
has_related_synonym: alkyl/aryl (non-methyl) transferase inhibitor
has_related_synonym: alkyl/aryl (non-methyl) transferase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: non-methyl alkyl/aryl transferase (EC 2.5.1.*) inhibitor
has_related_synonym: non-methyl alkyl/aryl transferase (EC 2.5.1.*) inhibitors
has_related_synonym: non-methyl alkyl/aryl transferase inhibitor
has_related_synonym: non-methyl alkyl/aryl transferase inhibitors
has_related_synonym: non-methyl-alkyl or aryl transferase inhibitor
has_related_synonym: non-methyl-alkyl or aryl transferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.6.* (nitrogenous group transferase) inhibitor
type: Class
subclass of: EC 2.* (transferase) inhibitor
definition: A transferase inhibitor that inhibits a nitrogenous group transferase (EC 2.6.*.*).
id: CHEBI:76665
has_related_synonym: EC 2.6.* inhibitor
has_related_synonym: EC 2.6.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: nitrogenous group transferase (EC 2.6.*) inhibitor
has_related_synonym: nitrogenous group transferase (EC 2.6.*) inhibitors
has_related_synonym: nitrogenous group transferase inhibitor
has_related_synonym: nitrogenous group transferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.* (P-containing group transferase) inhibitor
type: Class
subclass of: EC 2.* (transferase) inhibitor
definition: A transferase inhibitor that inhibits the action of a phosphorus-containing group transferase (EC 2.7.*.*).
id: CHEBI:76668
has_related_synonym: EC 2.7.* (P-containing group transferase) inhibitors
has_related_synonym: EC 2.7.* (phosphorus-containing group transferase) inhibitor
has_related_synonym: EC 2.7.* (phosphorus-containing group transferase) inhibitors
has_related_synonym: EC 2.7.* inhibitor
has_related_synonym: EC 2.7.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: phosphorus-containing group transferase (EC 2.7.*) inhibitor
has_related_synonym: phosphorus-containing group transferase (EC 2.7.*) inhibitors
has_related_synonym: phosphorus-containing group transferase inhibitor
has_related_synonym: phosphorus-containing group transferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.8.* (S-containing group transferase) inhibitor
type: Class
subclass of: EC 2.* (transferase) inhibitor
definition: A transferase inhibitor that interferes with the action of a sulfur-containing group transferase (EC 2.8.*.*).
id: CHEBI:76676
has_exact_synonym: EC 2.8.* (S-containing group transferase) inhibitor
has_related_synonym: EC 2.8.* (S-containing group transferase) inhibitors
has_related_synonym: EC 2.8.* inhibitor
has_related_synonym: EC 2.8.* inhibitors
has_related_synonym: S-containing group transferase inhibitor
has_related_synonym: S-containing group transferase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: sulfur-containing group transferase (EC 2.8.*) inhibitor
has_related_synonym: sulfur-containing group transferase (EC 2.8.*) inhibitors
has_related_synonym: sulfur-containing group transferase inhibitor
has_related_synonym: sulfur-containing group transferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.9.* (Se-containing group transferase) inhibitor
type: Class
subclass of: EC 2.* (transferase) inhibitor
definition: A transferase inhibitor that interferes with the action of a selenium-containing group transferase (EC 2.9.*.*).
id: CHEBI:76677
has_related_synonym: EC 2.9.* (Se-containing group transferase) inhibitors
has_related_synonym: EC 2.9.* inhibitor
has_related_synonym: EC 2.9.* inhibitors
has_related_synonym: Se-containing group transferase inhibitor
has_related_synonym: Se-containing group transferase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: selenium-containing group transferase (EC 2.9.*) inhibitor
has_related_synonym: selenium-containing group transferase (EC 2.9.*) inhibitors
has_related_synonym: selenium-containing group transferase inhibitor
has_related_synonym: selenium-containing group transferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.10.* (Mo- or W-containing group transferase) inhibitor
type: Class
subclass of: EC 2.* (transferase) inhibitor
definition: A transferase inhibitor that interferes with the action of a molybdenum- or tungsten-containing group transferase (EC 2.10.*.*).
id: CHEBI:76681
has_related_synonym: EC 2.10.* (Mo- or W-containing group transferase) inhibitors
has_related_synonym: EC 2.10.* inhibitor
has_related_synonym: EC 2.10.* inhibitors
has_related_synonym: Mo- or W-containing group transferase (EC 2.10.*) inhibitor
has_related_synonym: Mo- or W-containing group transferase (EC 2.10.*) inhibitors
has_related_synonym: Mo- or W-containing group transferase inhibitor
has_related_synonym: Mo- or W-containing group transferase inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 5.1.* (racemase/epimerase) inhibitor
type: Class
subclass of: EC 5.* (isomerase) inhibitor
definition: An isomerase inhibitor interfering with the action of a racemase or epimerase (EC 5.1.*.*).
id: CHEBI:76692
has_related_synonym: EC 5.1.* (racemase/epimerase) inhibitors
has_related_synonym: EC 5.1.* inhibitor
has_related_synonym: EC 5.1.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: racemase and epimerase (EC 5.1*) inhibitor
has_related_synonym: racemase and epimerase (EC 5.1*) inhibitors
has_related_synonym: racemase and epimerase inhibitor
has_related_synonym: racemase and epimerase inhibitors
has_related_synonym: racemase/epimerase inhibitor
has_related_synonym: racemase/epimerase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 5.2.* (cis-trans-isomerase) inhibitor
type: Class
subclass of: EC 5.* (isomerase) inhibitor
definition: An isomerase inhibitor interfering with the action of a cis-trans-isomerase (EC 5.2.*.*).
id: CHEBI:76693
has_related_synonym: EC 5.2.* (cis-trans-isomerase) inhibitors
has_related_synonym: EC 5.2.* inhibitor
has_related_synonym: EC 5.2.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: cis-trans-isomerase (EC5.2.*) inhibitor
has_related_synonym: cis-trans-isomerase (EC5.2.*) inhibitors
has_related_synonym: cis-trans-isomerase inhibitor
has_related_synonym: cis-trans-isomerase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 5.3.* (intramolecular oxidoreductase) inhibitor
type: Class
subclass of: EC 5.* (isomerase) inhibitor
definition: An isomerase inhibitor that interferes with the action of an intramolecular oxidoreductase (EC 5.3.*.*).
id: CHEBI:76694
has_related_synonym: EC 5.3.* (intramolecular oxidoreductase) inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: intramolecular oxidoreductase (EC 5.3.*) inhibitor
has_related_synonym: intramolecular oxidoreductase (EC 5.3.*) inhibitors
has_related_synonym: intramolecular oxidoreductase inhibitor
has_related_synonym: intramolecular oxidoreductase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 5.4.* (intramolecular transferase) inhibitor
type: Class
subclass of: EC 5.* (isomerase) inhibitor
definition: An isomerase inhibitor that interferes with the action of an intramolecular transferase (EC 5.4.*.*).
id: CHEBI:76695
has_related_synonym: EC 5.4.* (intramolecular transferase) inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: intramolecular transferase (EC 5.4.*) inhibitor
has_related_synonym: intramolecular transferase (EC 5.4.*) inhibitors
has_related_synonym: intramolecular transferase inhibitor
has_related_synonym: intramolecular transferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 5.5.* (intramolecular lyase) inhibitor
type: Class
subclass of: EC 5.* (isomerase) inhibitor
definition: An isomerase inhibitor that interferes with the action of an intramolecular lyase (EC 5.5.*.*).
id: CHEBI:76696
has_related_synonym: EC 5.5.* (intramolecular lyase) inhibitors
has_related_synonym: EC 5.5.* inhibitor
has_related_synonym: EC 5.5.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: intramolecular lyase inhibitor
has_related_synonym: intramolecular lyase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 5.99.* (other isomerases) inhibitor
type: Class
subclass of: EC 5.* (isomerase) inhibitor
definition: An isomerase inhibitor that interferes with the action of any member of the group of 'other isomerases' (EC 5.99.*.*).
id: CHEBI:76697
has_related_synonym: EC 5.99.* (miscellaneous isomerases) inhibitor
has_related_synonym: EC 5.99.* (miscellaneous isomerases) inhibitors
has_related_synonym: EC 5.99.* (other isomerase) inhibitor
has_related_synonym: EC 5.99.* (other isomerase) inhibitors
has_related_synonym: EC 5.99.* (other isomerases) inhibitors
has_related_synonym: EC 5.99.* inhibitor
has_related_synonym: EC 5.99.* inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 6.1.* (C-O bond-forming ligase) inhibitor
type: Class
subclass of: EC 6.* (ligase) inhibitor
definition: A ligase inhibitor that interferes with the action of a C-O bond-forming ligase (EC 6.1.*.*).
has_related_synonym: C-O bond-forming ligase (EC 6.1.*) inhibitor
has_related_synonym: C-O bond-forming ligase (EC 6.1.*) inhibitors
has_related_synonym: C-O bond-forming ligase inhibitor
has_related_synonym: C-O bond-forming ligase inhibitors
id: CHEBI:76706
has_related_synonym: EC 6.1.* (C-O bond-forming ligase) inhibitors
has_related_synonym: EC 6.1.* inhibitor
has_related_synonym: EC 6.1.* inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 6.2.* (C-S bond-forming ligase) inhibitor
type: Class
subclass of: EC 6.* (ligase) inhibitor
definition: A ligase inhibitor that interferes with the action of a C-S bond-forming ligase (EC 6.2.*.*).
has_related_synonym: C-S bond-forming ligase (EC 6.2.*) inhibitor
has_related_synonym: C-S bond-forming ligase (EC 6.2.*) inhibitors
has_related_synonym: C-S bond-forming ligase inhibitor
has_related_synonym: C-S bond-forming ligase inhibitors
id: CHEBI:76707
has_related_synonym: EC 6.2.* (C-S bond-forming ligase) inhibitors
has_related_synonym: EC 6.2.* inhibitor
has_related_synonym: EC 6.2.* inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 6.6.* (N-metal bond-forming ligase) inhibitor
type: Class
subclass of: EC 6.* (ligase) inhibitor
definition: A ligase inhibitor which interferes with the action of a nitrogen-metal bond-forming ligase (EC 6.6.*.*).
id: CHEBI:76708
has_related_synonym: EC 6.6.* (N-metal bond-forming ligase) inhibitors
has_related_synonym: EC 6.6.* inhibitor
has_related_synonym: EC 6.6.* inhibitors
has_related_synonym: N-metal bond-forming ligase (EC 6.6.*) inhibitor
has_related_synonym: N-metal bond-forming ligase (EC 6.6.*) inhibitors
has_related_synonym: N-metal bond-forming ligase inhibitor
has_related_synonym: N-metal bond-forming ligase inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 4.* (lyase) inhibitor
type: Class
subclass of: enzyme inhibitor
definition: An enzyme inhibitor which interferes with the action of a lyase (EC 4.*.*.*). Lyases are enzymes cleaving C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation.
id: CHEBI:76710
has_related_synonym: EC 4.* (lyase) inhibitors
has_related_synonym: EC 4.* inhibitor
has_related_synonym: EC 4.* inhibitors
has_related_synonym: EC 4.*.*.* inhibitor
has_related_synonym: EC 4.*.*.* inhibitors
database_cross_reference: Wikipedia:Lyase
has_obo_namespace: chebi_ontology
has_related_synonym: lyase (EC 4.*) inhibitor
has_related_synonym: lyase (EC 4.*) inhibitorS
has_related_synonym: lyase inhibitor
has_related_synonym: lyase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 4.1.* (C-C lyase) inhibitor
type: Class
subclass of: EC 4.* (lyase) inhibitor
definition: A lyase inhibitor which inhibits the action of a C-C lyase (EC 4.1.*.*).
has_related_synonym: C-C lyase (EC 4.1.*) inhibitor
has_related_synonym: C-C lyase (EC 4.1.*) inhibitors
has_related_synonym: C-C lyase inhibitor
has_related_synonym: C-C lyase inhibitors
id: CHEBI:76711
has_related_synonym: EC 4.1.* (C-C lyase) inhibitors
has_related_synonym: EC 4.1.* inhibitor
has_related_synonym: EC 4.1.* inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 4.2.* (C-O lyase) inhibitor
type: Class
subclass of: EC 4.* (lyase) inhibitor
definition: A lyase inhibitor which inhibits the action of a C-O lyase (EC 4.2.*.*).
has_related_synonym: C-O lyase (EC 4.2.*) inhibitor
has_related_synonym: C-O lyase (EC 4.2.*) inhibitors
has_related_synonym: C-O lyase inhibitor
has_related_synonym: C-O lyase inhibitors
id: CHEBI:76712
has_related_synonym: EC 4.2.* (C-O lyase) inhibitors
has_related_synonym: EC 4.2.* inhibitor
has_related_synonym: EC 4.2.* inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 4.3.* (C-N lyase) inhibitor
type: Class
subclass of: EC 4.* (lyase) inhibitor
definition: A lyase inhibitor which inhibits the action of a C-N lyase (EC 4.3.*.*).
has_related_synonym: C-N lyase (EC 4.3.*) inhibitor
has_related_synonym: C-N lyase (EC 4.3.*) inhibitors
has_related_synonym: C-N lyase inhibitor
has_related_synonym: C-N lyase inhibitors
id: CHEBI:76713
has_related_synonym: EC 4.3.* (C-N lyase) inhibitors
has_related_synonym: EC 4.3.* inhibitor
has_related_synonym: EC 4.3.* inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 4.4.* (C-S lyase) inhibitor
type: Class
subclass of: EC 4.* (lyase) inhibitor
definition: A lyase inhibitor which inhibits the action of a C-S lyase (EC 4.4.*.*).
has_related_synonym: C-S lyase (EC 4.4.*) inhibitor
has_related_synonym: C-S lyase (EC 4.4.*) inhibitors
has_related_synonym: C-S lyase inhibitor
has_related_synonym: C-S lyase inhibitors
id: CHEBI:76714
has_related_synonym: EC 4.4.* (C-S lyase) inhibitors
has_related_synonym: EC 4.4.* inhibitor
has_related_synonym: EC 4.4.* inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 4.5.* (C-halide lyase) inhibitor
type: Class
subclass of: EC 4.* (lyase) inhibitor
definition: A lyase inhibitor which inhibits the action of a C-halide lyase (EC 4.5.*.*).
has_related_synonym: C-halide lyase (EC 4.5.*) inhibitor
has_related_synonym: C-halide lyase (EC 4.5.*) inhibitors
has_related_synonym: C-halide lyase inhibitor
has_related_synonym: C-halide lyase inhibitors
id: CHEBI:76715
has_related_synonym: EC 4.5.* (C-halide lyase) inhibitors
has_related_synonym: EC 4.5.* inhibitor
has_related_synonym: EC 4.5.* inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 4.6.* (P-O lyase) inhibitor
type: Class
subclass of: EC 4.* (lyase) inhibitor
definition: A lyase inhibitor which inhibits the action of a P-O lyase (EC 4.6.*.*).
id: CHEBI:76716
has_related_synonym: EC 4.6.* (P-O lyase) inhibitors
has_related_synonym: EC 4.6.* inhibitor
has_related_synonym: EC 4.6.* inhibitors
has_related_synonym: P-O lyase (EC 4.6.*) inhibitor
has_related_synonym: P-O lyase (EC 4.6.*) inhibitors
has_related_synonym: P-O lyase inhibitor
has_related_synonym: P-O lyase inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 4.7.* (C-P lyase) inhibitor
type: Class
subclass of: EC 4.* (lyase) inhibitor
definition: A lyase inhibitor which inhibits the action of a C-P lyase (EC 4.6.*.*).
has_related_synonym: C-P lyase (EC 4.7.*) inhibitor
has_related_synonym: C-P lyase (EC 4.7.*) inhibitors
has_related_synonym: C-P lyase inhibitor
has_related_synonym: C-P lyase inhibitors
id: CHEBI:76717
has_related_synonym: EC 4.7.* (C-P lyase) inhibitors
has_related_synonym: EC 4.7.* inhibitor
has_related_synonym: EC 4.7.* inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 4.99.* (miscellaneous lyase) inhibitor
type: Class
subclass of: EC 4.* (lyase) inhibitor
definition: A lyase inhibitor which interferes with the activity of a lyase in the EC 4.99.*.* group.
id: CHEBI:76718
has_related_synonym: EC 4.99.* (miscellaneous lyase) inhibitors
has_related_synonym: EC 4.99.* (other lyase) inhibitor
has_related_synonym: EC 4.99.* (other lyase) inhibitors
has_related_synonym: EC 4.99.* inhibitor
has_related_synonym: EC 4.99.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: miscellaneous lyase (EC 4.99.*) inhibitor
has_related_synonym: miscellaneous lyase (EC 4.99.*) inhibitors
has_related_synonym: miscellaneous lyase inhibitor
has_related_synonym: miscellaneous lyase inhibitors
has_related_synonym: other lyase (EC 4.99.*) inhibitor
has_related_synonym: other lyase (EC 4.99.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

antisense oligonucleotide
type: Class
subclass of: biochemical role
definition: A synthetic oligonucleotide whose base sequence is complementary to a gene's messenger RNA (mRNA) and which will bind with the mRNA inactivating it.
id: CHEBI:76720
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 1.* (oxidoreductase) inhibitor
type: Class
subclass of: enzyme inhibitor
definition: An enzyme inhibitor which interferes with the action of an oxidoreductase (EC 1.*.*.*).
id: CHEBI:76725
has_related_synonym: EC 1.* (oxidoreductase) inhibitors
has_related_synonym: EC 1.* inhibitor
has_related_synonym: EC 1.* inhibitors
database_cross_reference: Wikipedia:Oxidoreductase
has_obo_namespace: chebi_ontology
has_related_synonym: oxidoreductase (EC 1.*) inhibitor
has_related_synonym: oxidoreductase (EC 1.*) inhibitors
has_related_synonym: oxidoreductase inhibitor
has_related_synonym: oxidoreductase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.1.* (oxidoreductase acting on donor CH-OH group) inhibitor
type: Class
subclass of: EC 1.* (oxidoreductase) inhibitor
definition: An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the CH-OH group of donors (EC 1.1.*.*).
id: CHEBI:76726
has_related_synonym: EC 1.1.* (oxidoreductase acting on donor CH-OH group) inhibitors
has_related_synonym: EC 1.1.* inhibitor
has_related_synonym: EC 1.1.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of oxidoreductase acting on CH-OH group of donor
has_related_synonym: inhibitor of oxidoreductase acting on CH-OH group of donors
has_related_synonym: inhibitors of oxidoreductase acting on CH-OH group of donor
has_related_synonym: inhibitors of oxidoreductase acting on CH-OH group of donors
has_related_synonym: oxidoreductase acting on donor CH-OH group (EC 1.1.*) inhibitor
has_related_synonym: oxidoreductase acting on donor CH-OH group (EC 1.1.*) inhibitors
has_related_synonym: oxidoreductase acting on donor CH-OH group inhibitor
has_related_synonym: oxidoreductase acting on donor CH-OH group inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.2.* (oxidoreductase acting on donor aldehyde/oxo group) inhibitor
type: Class
subclass of: EC 1.* (oxidoreductase) inhibitor
definition: An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the aldehyde or oxo group of donors (EC 1.2.*.*).
id: CHEBI:76727
has_related_synonym: EC 1.2.* (oxidoreductase acting on donor aldehyde or oxo group) inhibitor
has_related_synonym: EC 1.2.* (oxidoreductase acting on donor aldehyde or oxo group) inhibitors
has_related_synonym: EC 1.2.* (oxidoreductase acting on donor aldehyde/oxo group) inhibitors
has_related_synonym: EC 1.2.* inhibitor
has_related_synonym: EC 1.2.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of oxidoreductase acting on aldehyde or oxo group of donor
has_related_synonym: inhibitor of oxidoreductase acting on aldehyde or oxo group of donors
has_related_synonym: inhibitor of oxidoreductase acting on aldehyde/oxo group of donor
has_related_synonym: inhibitor of oxidoreductase acting on aldehyde/oxo group of donors
has_related_synonym: inhibitors of oxidoreductase acting on aldehyde or oxo group of donor
has_related_synonym: inhibitors of oxidoreductase acting on aldehyde or oxo group of donors
has_related_synonym: inhibitors of oxidoreductase acting on aldehyde/oxo group of donor
has_related_synonym: inhibitors of oxidoreductase acting on aldehyde/oxo group of donors
has_related_synonym: oxidoreductase acting on donor aldehyde or oxo group (EC 1.2.*) inhibitor
has_related_synonym: oxidoreductase acting on donor aldehyde or oxo group (EC 1.2.*) inhibitors
has_related_synonym: oxidoreductase acting on donor aldehyde or oxo group inhibitor
has_related_synonym: oxidoreductase acting on donor aldehyde or oxo group inhibitors
has_related_synonym: oxidoreductase acting on donor aldehyde/oxo group (EC 1.2.*) inhibitor
has_related_synonym: oxidoreductase acting on donor aldehyde/oxo group (EC 1.2.*) inhibitors
has_related_synonym: oxidoreductase acting on donor aldehyde/oxo group inhibitor
has_related_synonym: oxidoreductase acting on donor aldehyde/oxo group inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor
type: Class
subclass of: EC 1.* (oxidoreductase) inhibitor
definition: An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the CH-CH group of donors (EC 1.3.*.*).
id: CHEBI:76729
has_related_synonym: EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitors
has_related_synonym: EC 1.3.* inhibitor
has_related_synonym: EC 1.3.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of oxidoreductase acting on CH-CH group of donor
has_related_synonym: inhibitor of oxidoreductase acting on CH-CH group of donors
has_related_synonym: inhibitors of oxidoreductase acting on CH-CH group of donor
has_related_synonym: inhibitors of oxidoreductase acting on CH-CH group of donors
has_related_synonym: oxidoreductase acting on donor CH-CH group (EC 1.3.*) inhibitor
has_related_synonym: oxidoreductase acting on donor CH-CH group (EC 1.3.*) inhibitors
has_related_synonym: oxidoreductase acting on donor CH-CH group inhibitor
has_related_synonym: oxidoreductase acting on donor CH-CH group inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor
type: Class
subclass of: EC 1.* (oxidoreductase) inhibitor
definition: An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the CH-NH2 group of donors (EC 1.4.*.*).
id: CHEBI:76730
has_exact_synonym: EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor
has_related_synonym: EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitors
has_related_synonym: EC 1.4.* inhibitor
has_related_synonym: EC 1.4.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of oxidoreductase acting on CH-NH2 group of donor
has_related_synonym: inhibitor of oxidoreductase acting on CH-NH2 group of donors
has_related_synonym: inhibitors of oxidoreductase acting on CH-NH2 group of donor
has_related_synonym: inhibitors of oxidoreductase acting on CH-NH2 group of donors
has_related_synonym: oxidoreductase acting on CH-NH2 group of donor inhibitor
has_related_synonym: oxidoreductase acting on CH-NH2 group of donor inhibitors
has_related_synonym: oxidoreductase acting on CH-NH2 group of donors (EC 1.4.*) inhibitor
has_related_synonym: oxidoreductase acting on CH-NH2 group of donors (EC 1.4.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.5.* (oxidoreductase acting on donor CH-NH group) inhibitor
type: Class
subclass of: EC 1.* (oxidoreductase) inhibitor
definition: An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the CH-NH group of donors (EC 1.5.*.*).
id: CHEBI:76731
has_related_synonym: EC 1.5.* (oxidoreductase acting on donor CH-NH group) inhibitors
has_related_synonym: EC 1.5.* inhibitor
has_related_synonym: EC 1.5.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of oxidoreductase acting on CH-NH group of donor
has_related_synonym: inhibitor of oxidoreductase acting on CH-NH group of donors
has_related_synonym: inhibitors of oxidoreductase acting on CH-NH group of donor
has_related_synonym: inhibitors of oxidoreductase acting on CH-NH group of donors
has_related_synonym: oxidoreductase acting on donor CH-NH group (EC 1.5.*) inhibitor
has_related_synonym: oxidoreductase acting on donor CH-NH group (EC 1.5.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.6.* (oxidoreductase acting on NADH or NADPH) inhibitor
type: Class
subclass of: EC 1.* (oxidoreductase) inhibitor
definition: An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on NADH or NADPH (EC 1.6.*.*).
id: CHEBI:76733
has_related_synonym: EC 1.6.* (oxidoreductase acting on NADH or NADPH) inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of oxidoreductase acting on NADH or NADPH
has_related_synonym: inhibitor of oxidoreductase acting on NADH or NADPH (EC 1.6.*)
has_related_synonym: inhibitors of oxidoreductase acting on NADH or NADPH
has_related_synonym: inhibitors of oxidoreductase acting on NADH or NADPH (EC 1.6.*)
has_related_synonym: oxidoreductase acting on NADH or NADPH (EC 1.6.*) inhibitor
has_related_synonym: oxidoreductase acting on NADH or NADPH (EC 1.6.*) inhibitors
has_related_synonym: oxidoreductase acting on NADH or NADPH inhibitor
has_related_synonym: oxidoreductase acting on NADH or NADPH inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.7.* (oxidoreductase acting on other nitrogenous compounds as donors) inhibitor
type: Class
subclass of: EC 1.* (oxidoreductase) inhibitor
definition: An oxidoreductase inhibitor which interferes with the action of an oxidoreductase of class EC 1.7.*.* (acting on other nitrogenous compounds as donors).
id: CHEBI:76734
has_related_synonym: EC 1.7.* (oxidoreductase acting on other nitrogenous compounds as donors) inhibitors
has_related_synonym: EC 1.7.* inhibitor
has_related_synonym: EC 1.7.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of oxidoreductase acting on other nitrogenous compounds as donors
has_related_synonym: inhibitor of oxidoreductase acting on other nitrogenous compounds as donors (EC 1.7.*)
has_related_synonym: inhibitors of oxidoreductase acting on other nitrogenous compounds as donors
has_related_synonym: inhibitors of oxidoreductase acting on other nitrogenous compounds as donors (EC 1.7.*)
in_subset: 3 STAR
imported from: chebi.owl

EC 1.8.* (oxidoreductase acting on sulfur group of donors) inhibitor
type: Class
subclass of: EC 1.* (oxidoreductase) inhibitor
definition: An oxidoreductase inhibitor which interferes with the action of an oxidoreductase of class EC 1.8.*.* (acting on a sulfur group of donors).
id: CHEBI:76735
has_related_synonym: EC 1.8.* (oxidoreductase acting on sulfur group of donors) inhibitors
has_related_synonym: EC 1.8.* inhibitor
has_related_synonym: EC 1.8.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: oxidoreductase acting on a sulfur group of donors (EC 1.8.*) inhibitor
has_related_synonym: oxidoreductase acting on a sulfur group of donors (EC 1.8.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.9.* (oxidoreductase acting on donor heme group) inhibitor
type: Class
subclass of: EC 1.* (oxidoreductase) inhibitor
definition: An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on a heme group of donors (EC 1.9.*.*).
id: CHEBI:76736
has_related_synonym: EC 1.9.* (oxidoreductase acting on a heme group of donors) inhibitor
has_related_synonym: EC 1.9.* (oxidoreductase acting on a heme group of donors) inhibitors
has_related_synonym: EC 1.9.* (oxidoreductase acting on donor heme group) inhibitors
has_related_synonym: EC 1.9.* inhibitor
has_related_synonym: EC 1.9.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: oxidoreductase acting on a heme group of donors (EC 1.9.*) inhibitor
has_related_synonym: oxidoreductase acting on a heme group of donors (EC 1.9.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.10.* (oxidoreductase acting on diphenols and related substances as donors) inhibitor
type: Class
subclass of: EC 1.* (oxidoreductase) inhibitor
definition: An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on diphenols and related substances as donors (EC 1.10.*.*).
id: CHEBI:76737
has_related_synonym: EC 1.10.* (oxidoreductase acting on diphenols and related substances as donors) inhibitors
has_related_synonym: EC 1.10.* (oxidoreductases acting on diphenols and related substances as donors) inhibitor
has_related_synonym: EC 1.10.* (oxidoreductases acting on diphenols and related substances as donors) inhibitors
has_related_synonym: EC 1.10.* inhibitor
has_related_synonym: EC 1.10.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of an oxidoreductase acting on diphenols and related substances as donor
has_related_synonym: inhibitor of an oxidoreductase acting on diphenols and related substances as donor (EC 1.10.*)
has_related_synonym: inhibitor of an oxidoreductase acting on diphenols and related substances as donors
has_related_synonym: inhibitors of an oxidoreductase acting on diphenols and related substances as donor
has_related_synonym: inhibitors of an oxidoreductase acting on diphenols and related substances as donor (EC 1.10.*)
has_related_synonym: inhibitors of an oxidoreductase acting on diphenols and related substances as donors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitor
type: Class
subclass of: EC 1.* (oxidoreductase) inhibitor
definition: An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on peroxide as donors (EC 1.11.*.*).
id: CHEBI:76738
has_related_synonym: EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitors
has_related_synonym: EC 1.11.* (oxidoreductases acting on peroxide as donors) inhibitor
has_related_synonym: EC 1.11.* (oxidoreductases acting on peroxide as donors) inhibitors
has_related_synonym: EC 1.11.* inhibitor
has_related_synonym: EC 1.11.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: oxidoreductase acting on peroxide as donors (EC 1.11.*) inhibitor
has_related_synonym: oxidoreductase acting on peroxide as donors (EC 1.11.*) inhibitors
has_related_synonym: oxidoreductases acting on peroxide as donors (EC 1.11.*) inhibitor
has_related_synonym: oxidoreductases acting on peroxide as donors (EC 1.11.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.12.* (oxidoreductase acting on hydrogen as donors) inhibitor
type: Class
subclass of: EC 1.* (oxidoreductase) inhibitor
definition: An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on hydrogen as donors (EC 1.12.*.*).
id: CHEBI:76739
has_related_synonym: EC 1.12.* (oxidoreductase acting on hydrogen as donors) inhibitors
has_related_synonym: EC 1.12.* (oxidoreductases acting on hydrogen as donors) inhibitor
has_related_synonym: EC 1.12.* (oxidoreductases acting on hydrogen as donors) inhibitors
has_related_synonym: EC 1.12.* inhibitor
has_related_synonym: EC 1.12.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of oxidoreductase acting on hydrogen as donors
has_related_synonym: inhibitor of oxidoreductase acting on hydrogen as donors (EC 1.12.*)
has_related_synonym: inhibitors of oxidoreductase acting on hydrogen as donors
has_related_synonym: inhibitors of oxidoreductase acting on hydrogen as donors (EC 1.12.*)
has_related_synonym: oxidoreductase acting on hydrogen as donors inhibitor
has_related_synonym: oxidoreductase acting on hydrogen as donors inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.13.* [oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases)] inhibitor
type: Class
subclass of: EC 1.* (oxidoreductase) inhibitor
definition: An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases), EC 1.13.*.*.
id: CHEBI:76740
has_related_synonym: EC 1.13.* [oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases)] inhibitors
has_related_synonym: EC 1.13.* inhibitor
has_related_synonym: EC 1.13.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases) (EC 1.13.*) inhibitor
has_related_synonym: oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases) (EC 1.13.*) inhibitors
has_related_synonym: oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases) inhibitor
has_related_synonym: oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor
type: Class
subclass of: EC 1.* (oxidoreductase) inhibitor
definition: An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on hydrogen as donors (EC 1.14.*.*).
id: CHEBI:76741
has_related_synonym: EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitors
has_related_synonym: EC 1.14.* inhibitor
has_related_synonym: EC 1.14.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*)
has_related_synonym: inhibitor of oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*)
has_related_synonym: inhibitors of oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*)
has_related_synonym: inhibitors of oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*)
has_related_synonym: oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*) inhibitor
has_related_synonym: oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*) inhibitors
has_related_synonym: oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen inhibitor
has_related_synonym: oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.15.* (oxidoreductase acting on superoxide as acceptor) inhibitor
type: Class
subclass of: EC 1.* (oxidoreductase) inhibitor
definition: An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on superoxide as acceptor (EC 1.15.*.*).
id: CHEBI:76742
has_related_synonym: EC 1.15.* (oxidoreductase acting on superoxide as acceptor) inhibitors
has_related_synonym: EC 1.15.* inhibitor
has_related_synonym: EC 1.15.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of oxidoreductase acting on superoxide as acceptor
has_related_synonym: inhibitor of oxidoreductase acting on superoxide as acceptor (EC 1.15.*)
has_related_synonym: inhibitors of oxidoreductase acting on superoxide as acceptor
has_related_synonym: inhibitors of oxidoreductase acting on superoxide as acceptor (EC 1.15.*)
has_related_synonym: oxidoreductase acting on superoxide as acceptor (EC 1.15.*) inhibitor
has_related_synonym: oxidoreductase acting on superoxide as acceptor (EC 1.15.*) inhibitors
has_related_synonym: oxidoreductase acting on superoxide as acceptor inhibitor
has_related_synonym: oxidoreductase acting on superoxide as acceptor inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.16.* (oxidoreductase oxidising metal ions) inhibitor
type: Class
subclass of: EC 1.* (oxidoreductase) inhibitor
definition: An oxidoreductase inhibitor which interferes with the action of an oxidoreductase oxidising metal ions (EC 1.16.*.*).
id: CHEBI:76743
has_related_synonym: EC 1.16.* (oxidoreductase oxidising metal ions) inhibitors
has_related_synonym: EC 1.16.* (oxidoreductase oxidizing metal ions) inhibitor
has_related_synonym: EC 1.16.* (oxidoreductase oxidizing metal ions) inhibitors
has_related_synonym: EC 1.16.* inhibitor
has_related_synonym: EC 1.16.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: oxidoreductase oxidising metal ions (EC 1.16.*) inhibitor
has_related_synonym: oxidoreductase oxidising metal ions (EC 1.16.*) inhibitors
has_related_synonym: oxidoreductase oxidising metal ions inhibitor
has_related_synonym: oxidoreductase oxidising metal ions inhibitors
has_related_synonym: oxidoreductase oxidizing metal ions (EC 1.16.*) inhibitor
has_related_synonym: oxidoreductase oxidizing metal ions (EC 1.16.*) inhibitors
has_related_synonym: oxidoreductase oxidizing metal ions inhibitor
has_related_synonym: oxidoreductase oxidizing metal ions inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitor
type: Class
subclass of: EC 1.* (oxidoreductase) inhibitor
definition: An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on CH or CH2 (EC 1.17.*.*).
id: CHEBI:76744
has_related_synonym: EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitors
has_related_synonym: EC 1.17.* inhibitor
has_related_synonym: EC 1.17.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: oxidoreductase acting on CH or CH2 (EC 1.17.*) inhibitor
has_related_synonym: oxidoreductase acting on CH or CH2 (EC 1.17.*) inhibitors
has_related_synonym: oxidoreductase acting on CH or CH2 inhibitor
has_related_synonym: oxidoreductase acting on CH or CH2 inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.18.* (oxidoreductase acting on Fe-S proteins as donors) inhibitor
type: Class
subclass of: EC 1.* (oxidoreductase) inhibitor
definition: An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on iron-sulfur proteins as donors (EC 1.18.*.*).
id: CHEBI:76745
has_related_synonym: EC 1.18.* (oxidoreductase acting on Fe-S proteins as donors) inhibitors
has_related_synonym: EC 1.18.* (oxidoreductase acting on iron-sulfur proteins as donors) inhibitor
has_related_synonym: EC 1.18.* (oxidoreductase acting on iron-sulfur proteins as donors) inhibitors
has_related_synonym: EC 1.18.* inhibitor
has_related_synonym: EC 1.18.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of oxidoreductase acting on Fe-S proteins as donors
has_related_synonym: inhibitor of oxidoreductase acting on iron-sulfur proteins as donors
has_related_synonym: inhibitors of oxidoreductase acting on Fe-S proteins as donors
has_related_synonym: inhibitors of oxidoreductase acting on iron-sulfur proteins as donors
has_related_synonym: inhibitors of oxidoreductases acting on iron-sulfur proteins as donors
has_related_synonym: oxidoreductase acting on Fe-S proteins as donors (EC 1.18.*) inhibitor
has_related_synonym: oxidoreductase acting on Fe-S proteins as donors (EC 1.18.*) inhibitors
has_related_synonym: oxidoreductase acting on iron-sulfur proteins as donors (EC 1.18.*) inhibitor
has_related_synonym: oxidoreductase acting on iron-sulfur proteins as donors (EC 1.18.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.19.* (oxidoreductase acting on reduced flavodoxin as donor) inhibitor
type: Class
subclass of: EC 1.* (oxidoreductase) inhibitor
definition: An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on reduced flavodoxin as donor (EC 1.19.*.*).
id: CHEBI:76746
has_related_synonym: EC 1.19.* (oxidoreductase acting on reduced flavodoxin as donor) inhibitors
has_related_synonym: EC 1.19.* inhibitor
has_related_synonym: EC 1.19.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of oxidoreductase acting on reduced flavodoxin as donor
has_related_synonym: inhibitor of oxidoreductase acting on reduced flavodoxin as donor (EC 1.19.*)
has_related_synonym: inhibitors of oxidoreductase acting on reduced flavodoxin as donor
has_related_synonym: inhibitors of oxidoreductase acting on reduced flavodoxin as donor (EC 1.19.*)
has_related_synonym: oxidoreductase acting on reduced flavodoxin as donor (EC 1.19.*) inhibitor
has_related_synonym: oxidoreductase acting on reduced flavodoxin as donor (EC 1.19.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.20.* (oxidoreductase acting on P or As in donors) inhibitor
type: Class
subclass of: EC 1.* (oxidoreductase) inhibitor
definition: An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on phosphorus or arsenic in donors (EC 1.20.*.*).
id: CHEBI:76747
has_related_synonym: EC 1.20.* (oxidoreductase acting on P or As in donors) inhibitors
has_related_synonym: EC 1.20.* (oxidoreductase acting on phosphorus or arsenic in donors) inhibitor
has_related_synonym: EC 1.20.* (oxidoreductase acting on phosphorus or arsenic in donors) inhibitors
has_related_synonym: EC 1.20.* inhibitor
has_related_synonym: EC 1.20.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: oxidoreductase acting on P or As in donors (EC 1.20.*) inhibitor
has_related_synonym: oxidoreductase acting on P or As in donors (EC 1.20.*) inhibitors
has_related_synonym: oxidoreductase acting on phosphorus or arsenic in donors (EC 1.20.*) inhibitor
has_related_synonym: oxidoreductase acting on phosphorus or arsenic in donors (EC 1.20.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.21.* (oxidoreductase acting on X-H and Y-H to form an X-Y bond) inhibitor
type: Class
subclass of: EC 1.* (oxidoreductase) inhibitor
definition: An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on X-H and Y-H to form an X-Y bond (EC 1.21.*.*).
id: CHEBI:76748
has_related_synonym: EC 1.21.* (oxidoreductase acting on X-H and Y-H to form an X-Y bond) inhibitors
has_related_synonym: EC 1.21.* inhibitor
has_related_synonym: EC 1.21.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: oxidoreductase acting on X-H and Y-H to form an X-Y bond (EC 1.21.*) inhibitor
has_related_synonym: oxidoreductase acting on X-H and Y-H to form an X-Y bond (EC 1.21.*) inhibitors
has_related_synonym: oxidoreductase acting on X-H and Y-H to form an X-Y bond inhibitor
has_related_synonym: oxidoreductase acting on X-H and Y-H to form an X-Y bond inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.22.* (oxidoreductase acting on halogen in donors) inhibitor
type: Class
subclass of: EC 1.* (oxidoreductase) inhibitor
definition: An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on halogen in donors (EC 1.22.*.*).
id: CHEBI:76750
has_related_synonym: EC 1.22.* (oxidoreductase acting on halogen in donors) inhibitors
has_related_synonym: EC 1.22.* inhibitor
has_related_synonym: EC 1.22.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of oxidoreductase acting on halogen in donors
has_related_synonym: inhibitor of oxidoreductase acting on halogen in donors (EC 1.22.*)
has_related_synonym: inhibitors of oxidoreductase acting on halogen in donors
has_related_synonym: inhibitors of oxidoreductase acting on halogen in donors (EC 1.22.*)
has_related_synonym: oxidoreductase acting on halogen in donors (EC 1.22.*) inhibitor
has_related_synonym: oxidoreductase acting on halogen in donors (EC 1.22.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.23.* (oxidoreductase acting on C-O-C group as acceptor) inhibitor
type: Class
subclass of: EC 1.* (oxidoreductase) inhibitor
definition: An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on C-O-C group as acceptor (EC 1.23.*.*).
id: CHEBI:76752
has_related_synonym: EC 1.23.* (oxidoreductase acting on C-O-C group as acceptor) inhibitors
has_related_synonym: EC 1.23.* inhibitor
has_related_synonym: EC 1.23.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of oxidoreductase acting on C-O-C group as acceptor
has_related_synonym: inhibitor of oxidoreductase acting on C-O-C group as acceptor (EC 1.23.*)
has_related_synonym: inhibitors of oxidoreductase acting on C-O-C group as acceptor
has_related_synonym: inhibitors of oxidoreductase acting on C-O-C group as acceptor (EC 1.23.*)
has_related_synonym: oxidoreductase acting on C-O-C group as acceptor (EC 1.23.*) inhibitor
has_related_synonym: oxidoreductase acting on C-O-C group as acceptor (EC 1.23.*) inhibitors
has_related_synonym: oxidoreductase acting on C-O-C group as acceptor inhibitor
has_related_synonym: oxidoreductase acting on C-O-C group as acceptor inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.97.* (other oxidoreductase) inhibitor
type: Class
subclass of: EC 1.* (oxidoreductase) inhibitor
definition: An oxidoreductase inhibitor which interferes with the action of any oxidoreductase that is classified as EC 1.97.*.*, (those oxidoreductases not included in any other EC 1.* category).
id: CHEBI:76753
has_related_synonym: EC 1.97.* (miscellaneous oxidoreductase) inhibitor
has_related_synonym: EC 1.97.* (miscellaneous oxidoreductase) inhibitors
has_related_synonym: EC 1.97.* (other oxidoreductase) inhibitors
has_related_synonym: EC 1.97.* inhibitor
has_related_synonym: EC 1.97.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of 'other' oxidoreductase (EC 1.97.*)
has_related_synonym: inhibitor of miscellaneous oxidoreductase (EC 1.97.*)
has_related_synonym: inhibitors of 'other' oxidoreductase (EC 1.97.*)
has_related_synonym: inhibitors of miscellaneous oxidoreductase (EC 1.97.*)
in_subset: 3 STAR
imported from: chebi.owl

EC 1.98.* (enzymes using H2 as reductant) inhibitor
type: Class
subclass of: EC 1.* (oxidoreductase) inhibitor
definition: An oxidoreductase inhibitor which interferes with the action of any oxidoreductase using H2 as reductant (EC 1.98.*.*).
id: CHEBI:76755
has_related_synonym: EC 1.98.* (enzymes using H2 as reductant) inhibitors
has_related_synonym: EC 1.98.* inhibitor
has_related_synonym: EC 1.98.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of enzymes using H2 as reductant (EC 1.98.*)
has_related_synonym: inhibitors of enzymes using H2 as reductant (EC 1.98.*)
in_subset: 3 STAR
imported from: chebi.owl

EC 1.99.* (other oxidoreductases using O2 as oxidant) inhibitor
type: Class
subclass of: EC 1.* (oxidoreductase) inhibitor
definition: An oxidoreductase inhibitor which interferes with the action of any oxidoreductase that is classified as EC 1.99.*.* (other oxidoreductases using O2 as oxidant).
id: CHEBI:76757
has_related_synonym: EC 1.99.* (other oxidoreductases using O2 as oxidant) inhibitors
has_related_synonym: EC 1.99.* inhibitor
has_related_synonym: EC 1.99.* inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 3.* (hydrolase) inhibitor
type: Class
subclass of: enzyme inhibitor
definition: Any enzyme inhibitor that interferes with the action of a hydrolase (EC 3.*.*.*).
id: CHEBI:76759
has_related_synonym: EC 3.* (hydrolase) inhibitors
has_related_synonym: EC 3.* inhibitor
has_related_synonym: EC 3.* inhibitors
has_related_synonym: EC 3.*.*.* inhibitor
has_related_synonym: EC 3.*.*.* inhibitors
database_cross_reference: Wikipedia:Hydrolase
has_obo_namespace: chebi_ontology
has_related_synonym: hydrolase (EC 3.*) inhibitor
has_related_synonym: hydrolase (EC 3.*) inhibitors
has_related_synonym: hydrolase inhibitor
has_related_synonym: hydrolase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.1.* (ester hydrolase) inhibitor
type: Class
subclass of: EC 3.* (hydrolase) inhibitor
definition: A hydrolase inhibitor that interferes with the action of any ester hydrolase (EC 3.1.*.*).
id: CHEBI:76760
has_related_synonym: EC 3.1.* (ester hydrolase) inhibitors
has_related_synonym: EC 3.1.* inhibitor
has_related_synonym: EC 3.1.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: ester hydrolase (EC 3.1.*) inhibitor
has_related_synonym: ester hydrolase (EC 3.1.*) inhibitors
has_related_synonym: ester hydrolase inhibitor
has_related_synonym: ester hydrolase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.2.* (glycosylase) inhibitor
type: Class
subclass of: EC 3.* (hydrolase) inhibitor
definition: A hydrolase inhibitor that interferes with the action of any glycosylase (EC 3.2.*.*).
id: CHEBI:76761
has_related_synonym: EC 3.2.* (glycosylase) inhibitors
has_related_synonym: EC 3.2.* inhibitor
has_related_synonym: EC 3.2.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: glycosylase (EC 3.2.*) inhibitor
has_related_synonym: glycosylase (EC 3.2.*) inhibitors
has_related_synonym: glycosylase inhibitor
has_related_synonym: glycosylase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.3.* (ether hydrolase) inhibitor
type: Class
subclass of: EC 3.* (hydrolase) inhibitor
definition: A hydrolase inhibitor that interferes with the action of any hydrolase acting on an ether bond (EC 3.3.*.*).
id: CHEBI:76762
has_related_synonym: EC 3.3.* (ether hydrolase) inhibitors
has_related_synonym: EC 3.3.* (hydrolase acting on ether bond) inhibitor
has_related_synonym: EC 3.3.* (hydrolase acting on ether bond) inhibitors
has_related_synonym: EC 3.3.* inhibitor
has_related_synonym: EC 3.3.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: ether hydrolase (EC 3.3.*) inhibitor
has_related_synonym: ether hydrolase (EC 3.3.*) inhibitors
has_related_synonym: ether hydrolase inhibitor
has_related_synonym: ether hydrolase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor
type: Class
subclass of: EC 3.* (hydrolase) inhibitor
definition: Any hydrolase inhibitor that interferes with the action of a hydrolase acting on C-N bonds, other than peptide bonds (EC 3.5.*.*).
id: CHEBI:76764
has_related_synonym: EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitor
has_related_synonym: EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitors
has_related_synonym: EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitor
has_related_synonym: EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitors
has_related_synonym: EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitors
has_related_synonym: EC 3.5.* inhibitor
has_related_synonym: EC 3.5.* inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 3.7.* (hydrolases acting on C-C bonds) inhibitor
type: Class
subclass of: EC 3.* (hydrolase) inhibitor
definition: Any hydrolase inhibitor that interferes with the action of a hydrolase acting on carbon-carbon bonds (EC 3.7.*.*).
id: CHEBI:76766
has_related_synonym: EC 3.7.* (hydrolases acting on C-C bonds) inhibitors
has_related_synonym: EC 3.7.* (hydrolases acting on carbon-carbon bonds) inhibitor
has_related_synonym: EC 3.7.* (hydrolases acting on carbon-carbon bonds) inhibitors
has_related_synonym: EC 3.7.* inhibitor
has_related_synonym: EC 3.7.* inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 3.8.* (hydrolases acting on halide bonds) inhibitor
type: Class
subclass of: EC 3.* (hydrolase) inhibitor
definition: Any hydrolase inhibitor that interferes with the action of a hydrolase acting on halide bonds (EC 3.8.*.*).
id: CHEBI:76767
has_related_synonym: EC 3.8.* (hydrolases acting on halide bonds) inhibitors
has_related_synonym: EC 3.8.* inhibitor
has_related_synonym: EC 3.8.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: hydrolases acting on halide bonds (EC 3.8.*) inhibitor
has_related_synonym: hydrolases acting on halide bonds (EC 3.8.*) inhibitors
has_related_synonym: inhibitor of hydrolases acting on halide bonds (EC 3.8.*)
has_related_synonym: inhibitors of hydrolases acting on halide bonds (EC 3.8.*)
in_subset: 3 STAR
imported from: chebi.owl

EC 3.9.* (hydrolases acting on P-N bonds) inhibitor
type: Class
subclass of: EC 3.* (hydrolase) inhibitor
definition: Any hydrolase inhibitor that interferes with the action of a hydrolase acting on phosphorus-nitrogen bonds (EC 3.9.*.*).
id: CHEBI:76768
has_related_synonym: EC 3.9.* (hydrolases acting on P-N bonds) inhibitors
has_related_synonym: EC 3.9.* (hydrolases acting on phosphorus-nitrogen bonds) inhibitor
has_related_synonym: EC 3.9.* (hydrolases acting on phosphorus-nitrogen bonds) inhibitors
has_related_synonym: EC 3.9.* inhibitor
has_related_synonym: EC 3.9.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: hydrolases acting on P-N bonds (EC 3.9.*) inhibitor
has_related_synonym: hydrolases acting on P-N bonds (EC 3.9.*) inhibitors
has_related_synonym: hydrolases acting on phosphorus-nitrogen bonds (EC 3.9.*) inhibitor
has_related_synonym: hydrolases acting on phosphorus-nitrogen bonds (EC 3.9.*) inhibitors
has_related_synonym: inhibitor of hydrolases acting on P-N bonds
has_related_synonym: inhibitor of hydrolases acting on P-N bonds (EC 3.9.*)
has_related_synonym: inhibitor of hydrolases acting on phosphorus-nitrogen bonds
has_related_synonym: inhibitor of hydrolases acting on phosphorus-nitrogen bonds (EC 3.9.*)
has_related_synonym: inhibitors of hydrolases acting on P-N bonds
has_related_synonym: inhibitors of hydrolases acting on P-N bonds (EC 3.9.*)
has_related_synonym: inhibitors of hydrolases acting on phosphorus-nitrogen bonds
has_related_synonym: inhibitors of hydrolases acting on phosphorus-nitrogen bonds (EC 3.9.*)
in_subset: 3 STAR
imported from: chebi.owl

EC 3.10.* (hydrolases acting on S-N bonds) inhibitor
type: Class
subclass of: EC 3.* (hydrolase) inhibitor
definition: Any hydrolase inhibitor that interferes with the action of a hydrolase acting on sulfur-nitrogen bonds (EC 3.10.*.*).
id: CHEBI:76769
has_related_synonym: EC 3.10.* (hydrolases acting on S-N bonds) inhibitors
has_related_synonym: EC 3.10.* (hydrolases acting on sulfur-nitrogen bonds) inhibitor
has_related_synonym: EC 3.10.* (hydrolases acting on sulfur-nitrogen bonds) inhibitors
has_related_synonym: EC 3.10.* inhibitor
has_related_synonym: EC 3.10.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: hydrolases acting on S-N bonds (EC 3.10.*) inhibitor
has_related_synonym: hydrolases acting on S-N bonds (EC 3.10.*) inhibitors
has_related_synonym: hydrolases acting on sulfur-nitrogen bonds (EC 3.10.*) inhibitor
has_related_synonym: hydrolases acting on sulfur-nitrogen bonds (EC 3.10.*) inhibitors
has_related_synonym: inhibitor of hydrolases acting on S-N bonds
has_related_synonym: inhibitor of hydrolases acting on S-N bonds (EC 3.10.*)
has_related_synonym: inhibitor of hydrolases acting on sulfur-nitrogen bonds
has_related_synonym: inhibitor of hydrolases acting on sulfur-nitrogen bonds (EC 3.10.*)
has_related_synonym: inhibitors of hydrolases acting on S-N bonds
has_related_synonym: inhibitors of hydrolases acting on S-N bonds (EC 3.10.*)
has_related_synonym: inhibitors of hydrolases acting on sulfur-nitrogen bonds
has_related_synonym: inhibitors of hydrolases acting on sulfur-nitrogen bonds (EC 3.10.*)
in_subset: 3 STAR
imported from: chebi.owl

EC 3.11.* (hydrolases acting on C-P bonds) inhibitor
type: Class
subclass of: EC 3.* (hydrolase) inhibitor
definition: Any hydrolase inhibitor that interferes with the action of a hydrolase acting on carbon-phosphorus bonds (EC 3.11.*.*).
id: CHEBI:76770
has_related_synonym: EC 3.11.* (hydrolases acting on C-P bonds) inhibitors
has_related_synonym: EC 3.11.* (hydrolases acting on carbon-phosphorus bonds) inhibitor
has_related_synonym: EC 3.11.* (hydrolases acting on carbon-phosphorus bonds) inhibitors
has_related_synonym: EC 3.11.* inhibitor
has_related_synonym: EC 3.11.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: hydrolases acting on C-P bonds (EC 3.11.*) inhibitor
has_related_synonym: hydrolases acting on C-P bonds (EC 3.11.*) inhibitors
has_related_synonym: hydrolases acting on carbon-phosphorus bonds (EC 3.11.*) inhibitor
has_related_synonym: hydrolases acting on carbon-phosphorus bonds (EC 3.11.*) inhibitors
has_related_synonym: inhibitor of hydrolases acting on C-P bonds
has_related_synonym: inhibitor of hydrolases acting on C-P bonds (EC 3.11.*)
has_related_synonym: inhibitor of hydrolases acting on carbon-phosphorus bonds
has_related_synonym: inhibitor of hydrolases acting on carbon-phosphorus bonds (EC 3.11.*)
has_related_synonym: inhibitors of hydrolases acting on C-P bonds
has_related_synonym: inhibitors of hydrolases acting on C-P bonds (EC 3.11.*)
has_related_synonym: inhibitors of hydrolases acting on carbon-phosphorus bonds
has_related_synonym: inhibitors of hydrolases acting on carbon-phosphorus bonds (EC 3.11.*)
in_subset: 3 STAR
imported from: chebi.owl

EC 3.12.* (hydrolases acting on S-S bonds) inhibitor
type: Class
subclass of: EC 3.* (hydrolase) inhibitor
definition: Any hydrolase inhibitor that interferes with the action of a hydrolase acting on sulfur-sulfur bonds (EC 3.12.*.*).
id: CHEBI:76771
has_related_synonym: EC 3.12.* (hydrolases acting on S-S bonds) inhibitors
has_related_synonym: EC 3.12.* (hydrolases acting on sulfur-sulfur bonds) inhibitor
has_related_synonym: EC 3.12.* (hydrolases acting on sulfur-sulfur bonds) inhibitors
has_related_synonym: EC 3.12.* inhibitor
has_related_synonym: EC 3.12.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: hydrolases acting on S-S bonds (EC 3.12.*) inhibitor
has_related_synonym: hydrolases acting on S-S bonds (EC 3.12.*) inhibitors
has_related_synonym: hydrolases acting on S-S bonds inhibitor
has_related_synonym: hydrolases acting on S-S bonds inhibitors
has_related_synonym: hydrolases acting on sulfur-sulfur bonds (EC 3.12.*) inhibitor
has_related_synonym: hydrolases acting on sulfur-sulfur bonds (EC 3.12.*) inhibitors
has_related_synonym: hydrolases acting on sulfur-sulfur bonds inhibitor
has_related_synonym: hydrolases acting on sulfur-sulfur bonds inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.13.* (hydrolases acting on C-S bonds) inhibitor
type: Class
subclass of: EC 3.* (hydrolase) inhibitor
definition: Any hydrolase inhibitor that interferes with the action of a hydrolase acting on carbon-sulfur bonds (EC 3.13.*.*).
id: CHEBI:76772
has_related_synonym: EC 3.13.* (hydrolases acting on C-S bonds) inhibitors
has_related_synonym: EC 3.13.* (hydrolases acting on carbon-sulfur bonds) inhibitor
has_related_synonym: EC 3.13.* (hydrolases acting on carbon-sulfur bonds) inhibitors
has_related_synonym: EC 3.13.* inhibitor
has_related_synonym: EC 3.13.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: hydrolases acting on C-S bonds (EC 3.13.*) inhibitor
has_related_synonym: hydrolases acting on C-S bonds (EC 3.13.*) inhibitors
has_related_synonym: hydrolases acting on C-S bonds inhibitor
has_related_synonym: hydrolases acting on C-S bonds inhibitors
has_related_synonym: hydrolases acting on carbon-sulfur bonds (EC 3.13.*) inhibitor
has_related_synonym: hydrolases acting on carbon-sulfur bonds (EC 3.13.*) inhibitors
has_related_synonym: hydrolases acting on carbon-sulfur bonds inhibitor
has_related_synonym: hydrolases acting on carbon-sulfur bonds inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.1.1.* (carboxylic ester hydrolase) inhibitor
type: Class
subclass of: EC 3.1.* (ester hydrolase) inhibitor
definition: An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of a carboxylic ester hydrolase (EC 3.1.1.*).
id: CHEBI:76773
has_related_synonym: EC 3.1.1.* (carboxylic ester hydrolase) inhibitors
has_related_synonym: EC 3.1.1.* inhibitor
has_related_synonym: EC 3.1.1.* inhibitors
has_related_synonym: carboxylic ester hydrolase (EC 3.1.1.*) inhibitor
has_related_synonym: carboxylic ester hydrolase (EC 3.1.1.*) inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor
type: Class
subclass of: EC 3.1.* (ester hydrolase) inhibitor
definition: An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of any phosphoric monoester hydrolase (EC 3.1.3.*).
id: CHEBI:76775
has_related_synonym: EC 3.1.3.* (phosphoric monoester hydrolase) inhibitors
has_related_synonym: EC 3.1.3.* inhibitor
has_related_synonym: EC 3.1.3.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of phosphoric monoester hydrolase
has_related_synonym: inhibitor of phosphoric monoester hydrolase (EC 3.1.3.*)
has_related_synonym: inhibitors of phosphoric monoester hydrolase
has_related_synonym: inhibitors of phosphoric monoester hydrolase (EC 3.1.3.*)
has_related_synonym: phosphoric monoester hydrolase (EC 3.1.3.*) inhibitor
has_related_synonym: phosphoric monoester hydrolase (EC 3.1.3.*) inhibitors
has_related_synonym: phosphoric monoester hydrolase inhibitor
has_related_synonym: phosphoric monoester hydrolase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
type: Class
subclass of: EC 3.4.21.* (serine endopeptidase) inhibitor
definition: Any EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of prolyl oligopeptidase (EC 3.4.21.26).
id: CHEBI:76779
has_related_synonym: EC 3.4.21.26 (prolyl oligopeptidase) inhibitors
has_related_synonym: EC 3.4.21.26 inhibitor
has_related_synonym: EC 3.4.21.26 inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: endoprolylpeptidase inhibitor
has_related_synonym: endoprolylpeptidase inhibitors
has_related_synonym: post-proline cleaving enzyme inhibitor
has_related_synonym: post-proline cleaving enzyme inhibitors
has_related_synonym: post-proline endopeptidase inhibitor
has_related_synonym: post-proline endopeptidase inhibitors
has_related_synonym: proline endopeptidase inhibitor
has_related_synonym: proline endopeptidase inhibitors
has_related_synonym: proline-specific endopeptidase inhibitor
has_related_synonym: proline-specific endopeptidase inhibitors
has_related_synonym: prolyl endopeptidase inhibitor
has_related_synonym: prolyl endopeptidase inhibitors
has_related_synonym: prolyl oligopeptidase (EC 3.4.21.26) inhibitor
has_related_synonym: prolyl oligopeptidase (EC 3.4.21.26) inhibitors
has_related_synonym: prolyl oligopeptidase inhibitor
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.15.* (peptidyl-dipeptidase) inhibitor
type: Class
subclass of: EC 3.4.* (hydrolases acting on peptide bond) inhibitor
definition: Any EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes with the activity of a peptidyl dipeptidase (EC 3.4.15.*).
id: CHEBI:76782
has_related_synonym: EC 3.4.15.* (peptidyl-dipeptidase) inhibitors
has_related_synonym: EC 3.4.15.* inhibitor
has_related_synonym: EC 3.4.15.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of peptidyl-dipeptidases
has_related_synonym: inhibitor of peptidyl-dipeptidases (EC 3.4.15.*)
has_related_synonym: inhibitors of peptidyl-dipeptidases
has_related_synonym: inhibitors of peptidyl-dipeptidases (EC 3.4.15.*)
has_related_synonym: peptidyl-dipeptidase (EC 3.4.15.*) inhibitor
has_related_synonym: peptidyl-dipeptidase (EC 3.4.15.*) inhibitors
has_related_synonym: peptidyl-dipeptidase inhibitor
has_related_synonym: peptidyl-dipeptidase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.1.26.* (endoribonucleases producing 5'-phosphomonoesters) inhibitor
type: Class
subclass of: EC 3.1.* (ester hydrolase) inhibitor
definition: An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of any endoribonuclease producing 5'-phosphomonoesters (EC 3.1.26.*).
id: CHEBI:76785
has_related_synonym: EC 3.1.26.* (endoribonucleases producing 5'-phosphomonoesters) inhibitors
has_related_synonym: EC 3.1.26.* inhibitor
has_related_synonym: EC 3.1.26.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: endoribonuclease producing 5'-phosphomonoesters (EC 3.1.26.*) inhibitor
has_related_synonym: endoribonuclease producing 5'-phosphomonoesters (EC 3.1.26.*) inhibitors
has_related_synonym: endoribonuclease producing 5'-phosphomonoesters inhibitor
has_related_synonym: endoribonuclease producing 5'-phosphomonoesters inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.11.* (aminopeptidase) inhibitor
type: Class
subclass of: EC 3.4.* (hydrolases acting on peptide bond) inhibitor
definition: An EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes wtih the action of any aminopeptidase (EC 3.4.11.*).
id: CHEBI:76787
has_related_synonym: EC 3.4.11.* (aminopeptidase) inhibitors
has_related_synonym: EC 3.4.11.* inhibitor
has_related_synonym: EC 3.4.11.* inhibitors
has_related_synonym: aminopeptidase (EC 3.4.11.*) inhibitor
has_related_synonym: aminopeptidase (EC 3.4.11.*) inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.14.* (dipeptidyl- and tripeptidyl-peptidases) inhibitor
type: Class
subclass of: EC 3.4.* (hydrolases acting on peptide bond) inhibitor
definition: An EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes with the activity of any dipeptidyl- and tripeptidyl-peptidase (EC 3.4.14.*).
id: CHEBI:76788
has_related_synonym: EC 3.4.14.* (dipeptidyl- and tripeptidyl-peptidases) inhibitors
has_related_synonym: EC 3.4.14.* inhibitor
has_related_synonym: EC 3.4.14.* inhibitors
has_related_synonym: EC 3.4.14.*(dipeptidyl-peptidases and tripeptidyl-peptidases) inhibitor
has_related_synonym: EC 3.4.14.*(dipeptidyl-peptidases and tripeptidyl-peptidases) inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: dipeptidyl- and tripeptidyl-peptidase (EC 3.4.14.*) inhibitor
has_related_synonym: dipeptidyl- and tripeptidyl-peptidase (EC 3.4.14.*) inhibitors
has_related_synonym: dipeptidyl- and tripeptidyl-peptidase inhibitor
has_related_synonym: dipeptidyl- and tripeptidyl-peptidase inhibitors
has_related_synonym: dipeptidyl- and tripeptidyl-peptidases (EC 3.4.14.*) inhibitor
has_related_synonym: dipeptidyl- and tripeptidyl-peptidases (EC 3.4.14.*) inhibitors
has_related_synonym: dipeptidyl- and tripeptidyl-peptidases inhibitor
has_related_synonym: dipeptidyl- and tripeptidyl-peptidases inhibitors
has_related_synonym: dipeptidyl-peptidases and tripeptidyl-peptidases (EC 3.4.14.*) inhibitor
has_related_synonym: dipeptidyl-peptidases and tripeptidyl-peptidases (EC 3.4.14.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.4.1.* (hexosyltransferase) inhibitor
type: Class
subclass of: EC 2.4.* (glycosyltransferase) inhibitor
definition: An EC 2.4.* (glycosyltransferase) inhibitor that interferes with the action of any hexosyltransferase (EC 2.4.1.*).
id: CHEBI:76789
has_related_synonym: EC 2.4.1.* (hexosyltransferase) inhibitors
has_related_synonym: EC 2.4.1.* inhibitor
has_related_synonym: EC 2.4.1.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: hexosyltransferase (EC 2.4.1.*) inhibitor
has_related_synonym: hexosyltransferase (EC 2.4.1.*) inhibitors
has_related_synonym: hexosyltransferase inhibitor
has_related_synonym: hexosyltransferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.4.2.* (pentosyltransferase) inhibitor
type: Class
subclass of: EC 2.4.* (glycosyltransferase) inhibitor
definition: An EC 2.4.* (glycosyltransferase) inhibitor that interferes with the action of any pentosyltransferase (EC 2.4.2.*).
id: CHEBI:76790
has_related_synonym: EC 2.4.2.* (pentosyltransferase) inhibitors
has_related_synonym: EC 2.4.2.* inhibitor
has_related_synonym: EC 2.4.2.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: pentosyltransferase (EC 2.4.2.*) inhibitor
has_related_synonym: pentosyltransferase (EC 2.4.2.*) inhibitors
has_related_synonym: pentosyltransferase inhibitor
has_related_synonym: pentosyltransferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.1.27.* (endoribonucleases producing other than 5'-phosphomonoesters) inhibitor
type: Class
subclass of: EC 3.1.* (ester hydrolase) inhibitor
definition: An EC 3.1.* (ester hydrolase) inhibitor that interferes with the activity of any endoribonuclease producing other than a 5'-phosphomonoesters (EC 3.1.27.*).
id: CHEBI:76791
has_related_synonym: EC 3.1.27.* (endoribonucleases producing other than 5'-phosphomonoesters) inhibitors
has_related_synonym: EC 3.1.27.* inhibitor
has_related_synonym: EC 3.1.27.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of endoribonucleases producing other than 5'-phosphomonoesters
has_related_synonym: inhibitor of endoribonucleases producing other than 5'-phosphomonoesters (EC 3.1.27.*)
has_related_synonym: inhibitors of endoribonucleases producing other than 5'-phosphomonoesters
has_related_synonym: inhibitors of endoribonucleases producing other than 5'-phosphomonoesters (EC 3.1.27.*)
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.22.36 (caspase-1) inhibitor
type: Class
subclass of: EC 3.4.22.* (cysteine endopeptidase) inhibitor
definition: Any EC 3.4.22.* (cysteine endopeptidase) inhibitor that interferes with the activity of caspase-1 (EC 3.4.22.36).
id: CHEBI:76795
has_related_synonym: EC 3.4.22.36 (caspase-1) inhibitors
has_related_synonym: EC 3.4.22.36 inhibitor
has_related_synonym: EC 3.4.22.36 inhibitors
has_related_synonym: ICE inhibitor
has_related_synonym: ICE inhibitors
database_cross_reference: Wikipedia:Caspase_1
has_related_synonym: caspase-1 (EC 3.4.22.36) inhibitor
has_related_synonym: caspase-1 (EC 3.4.22.36) inhibitors
has_related_synonym: caspase-1 inhibitor
has_related_synonym: caspase-1 inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: interleukin 1 converting enzyme inhibitor
has_related_synonym: interleukin 1 converting enzyme inhibitors
has_related_synonym: interleukin 1beta converting enzyme inhibitor
has_related_synonym: interleukin 1beta converting enzyme inhibitors
has_related_synonym: interleukin 1beta precursor proteinase inhibitor
has_related_synonym: interleukin 1beta precursor proteinase inhibitors
has_related_synonym: interleukin 1beta-converting endopeptidase inhibitor
has_related_synonym: interleukin 1beta-converting endopeptidase inhibitors
has_related_synonym: interleukin 1beta-converting enzyme inhibitor
has_related_synonym: interleukin 1beta-converting enzyme inhibitors
has_related_synonym: interleukin-1 beta convertase precursor inhibitor
has_related_synonym: interleukin-1 beta convertase precursor inhibitors
has_related_synonym: interleukin-1beta convertase inhibitor
has_related_synonym: interleukin-1beta convertase inhibitors
has_related_synonym: interleukin-1beta converting enzyme inhibitor
has_related_synonym: interleukin-1beta converting enzyme inhibitors
has_related_synonym: interleukin-1beta precursor proteinase inhibitor
has_related_synonym: interleukin-1beta precursor proteinase inhibitors
has_related_synonym: precursor interleukin-1beta converting enzyme inhibitor
has_related_synonym: precursor interleukin-1beta converting enzyme inhibitors
has_related_synonym: pro-interleukin 1beta proteinase inhibitor
has_related_synonym: pro-interleukin 1beta proteinase inhibitors
has_related_synonym: prointerleukin 1beta protease inhibitor
has_related_synonym: prointerleukin 1beta protease inhibitors
has_related_synonym: protease A inhibitor
has_related_synonym: protease A inhibitors
has_related_synonym: protease VII inhibitor
has_related_synonym: protease VII inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.22.* (cysteine endopeptidase) inhibitor
type: Class
subclass of: EC 3.4.* (hydrolases acting on peptide bond) inhibitor
definition: An EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes with the action of any cysteine endopeptidase (EC 3.4.22.*).
id: CHEBI:76796
has_related_synonym: EC 3.4.22.* (cysteine endopeptidase) inhibitors
has_related_synonym: EC 3.4.22.* inhibitor
has_related_synonym: EC 3.4.22.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: cysteine endopeptidase (EC 3.4.22.*) inhibitor
has_related_synonym: cysteine endopeptidase (EC 3.4.22.*) inhibitors
has_related_synonym: cysteine endopeptidase inhibitor
has_related_synonym: cysteine endopeptidase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.5.1.18 (glutathione transferase) inhibitor
type: Class
subclass of: EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor
definition: An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of a glutathione transferase (EC 2.5.1.18).
id: CHEBI:76797
has_related_synonym: EC 2.5.1.18 (glutathione transferase) inhibitors
has_related_synonym: EC 2.5.1.18 inhibitor
has_related_synonym: EC 2.5.1.18 inhibitors
has_related_synonym: RX:glutathione R-transferase inhibitor
has_related_synonym: RX:glutathione R-transferase inhibitors
has_related_synonym: S-(hydroxyalkyl)glutathione lyase inhibitor
has_related_synonym: S-(hydroxyalkyl)glutathione lyase inhibitors
database_cross_reference: Wikipedia:Glutathione_S-transferase
has_obo_namespace: chebi_ontology
has_related_synonym: glutathione S-alkyl transferase inhibitor
has_related_synonym: glutathione S-alkyl transferase inhibitors
has_related_synonym: glutathione S-alkyltransferase inhibitor
has_related_synonym: glutathione S-alkyltransferase inhibitors
has_related_synonym: glutathione S-aralkyltransferase inhibitor
has_related_synonym: glutathione S-aralkyltransferase inhibitors
has_related_synonym: glutathione S-aryltransferase inhibitor
has_related_synonym: glutathione S-aryltransferase inhibitors
has_related_synonym: glutathione S-transferase inhibitor
has_related_synonym: glutathione S-transferase inhibitors
has_related_synonym: glutathione transferase (EC 2.5.1.18) inhibitor
has_related_synonym: glutathione transferase (EC 2.5.1.18) inhibitors
has_related_synonym: glutathione transferase inhibitor
has_related_synonym: glutathione transferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.14.15.4 (steroid 11beta-monooxygenase) inhibitor
type: Class
subclass of: EC 1.14.15.* (oxidoreductase acting on paired donors, with reduced Fe-S protein as one donor, incorporating 1 O atom) inhibitor
definition: An EC 1.14.15.* (oxidoreductase acting on paired donors, with reduced iron-sulfur protein as one donor, incorporating 1 atom of oxygen) inhibitor that interferes with the action of steroid 11beta-monooxygenase (EC 1.14.15.4).
id: CHEBI:76798
has_related_synonym: EC 1.14.15.4 (steroid 11beta-monooxygenase) inhibitors
has_related_synonym: EC 1.14.15.4 inhibitor
has_related_synonym: EC 1.14.15.4 inhibitors
database_cross_reference: Wikipedia:Steroid_11-beta-hydroxylase
has_obo_namespace: chebi_ontology
has_related_synonym: cytochrome p450 XIB1 inhibitor
has_related_synonym: cytochrome p450 XIB1 inhibitors
has_related_synonym: steroid 11beta-hydroxylase inhibitor
has_related_synonym: steroid 11beta-hydroxylase inhibitors
has_related_synonym: steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor
has_related_synonym: steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitors
has_related_synonym: steroid 11beta-monooxygenase inhibitors
has_related_synonym: steroid 11beta/18-hydroxylase inhibitor
has_related_synonym: steroid 11beta/18-hydroxylase inhibitors
has_related_synonym: steroid,reduced-adrenodoxin:oxygen oxidoreductase (11beta-hydroxylating) inhibitor
has_related_synonym: steroid,reduced-adrenodoxin:oxygen oxidoreductase (11beta-hydroxylating) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor
type: Class
subclass of: EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor
definition: An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide linear amide C-N hydrolase (EC 3.5.1.*).
id: CHEBI:76807
has_related_synonym: EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitors
has_related_synonym: EC 3.5.1.* inhibitor
has_related_synonym: EC 3.5.1.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitor
has_related_synonym: non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.5.2.* (non-peptide cyclic amide C-N hydrolase) inhibitor
type: Class
subclass of: EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor
definition: An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide cyclic amide C-N hydrolase (EC 3.5.2.*).
id: CHEBI:76808
has_related_synonym: EC 3.5.2.* (non-peptide cyclic amide C-N hydrolase) inhibitors
has_related_synonym: EC 3.5.2.* inhibitor
has_related_synonym: EC 3.5.2.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: non-peptide cyclic amide C-N hydrolase (EC 3.5.2.*) inhibitor
has_related_synonym: non-peptide cyclic amide C-N hydrolase (EC 3.5.2.*) inhibitors
has_related_synonym: non-peptide cyclic amide C-N hydrolase inhibitor
has_related_synonym: non-peptide cyclic amide C-N hydrolase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.5.4.* (non-peptide cyclic amidine C-N hydrolase) inhibitor
type: Class
subclass of: EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor
definition: An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide cyclic amidine C-N hydrolase (EC 3.5.4.*).
id: CHEBI:76809
has_related_synonym: EC 3.5.4.* (non-peptide cyclic amidine C-N hydrolase) inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: non-peptide cyclic amidine C-N hydrolase (EC 3.5.4.*) inhibitor
has_related_synonym: non-peptide cyclic amidine C-N hydrolase (EC 3.5.4.*) inhibitors
has_related_synonym: non-peptide cyclic amidine C-N hydrolase inhibitor
has_related_synonym: non-peptide cyclic amidine C-N hydrolase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.1.4.12 (sphingomyelin phosphodiesterase) inhibitor
type: Class
subclass of: EC 3.1.4.* (phosphoric diester hydrolase) inhibitor
definition: An EC 3.1.4.* (phosphoric diester hydrolase) inhibitor that interferes with the action of sphingomyelin phosphodiesterase (EC 3.1.4.12).
id: CHEBI:76811
has_related_synonym: EC 3.1.4.12 (sphingomyelin phosphodiesterase) inhibitors
has_related_synonym: EC 3.1.4.12 inhibitor
has_related_synonym: EC 3.1.4.12 inhibitors
has_related_synonym: SMase inhibitor
has_related_synonym: SMase inhibitors
database_cross_reference: Wikipedia:Sphingomyelin_phosphodiesterase
has_related_synonym: acid sphingomyelinase inhibitor
has_related_synonym: acid sphingomyelinase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: neutral sphingomyelinase inhibitor
has_related_synonym: neutral sphingomyelinase inhibitors
has_related_synonym: sphingomyelin cholinephosphohydrolase inhibitor
has_related_synonym: sphingomyelin cholinephosphohydrolase inhibitors
has_related_synonym: sphingomyelin phosphodiesterase (EC 3.1.4.12) inhibitor
has_related_synonym: sphingomyelin phosphodiesterase (EC 3.1.4.12) inhibitors
has_related_synonym: sphingomyelin phosphodiesterase inhibitor
has_related_synonym: sphingomyelin phosphodiesterase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.11.* (protein-serine/threonine kinase) inhibitor
type: Class
subclass of: protein kinase inhibitor
subclass of: EC 2.7.* (P-containing group transferase) inhibitor
definition: An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any protein-serine/threonine kinase (EC 2.7.11.*).
id: CHEBI:76812
has_related_synonym: EC 2.7.11.* (protein-serine/threonine kinase) inhibitors
has_related_synonym: EC 2.7.11.* inhibitor
has_related_synonym: EC 2.7.11.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: protein-serine/threonine kinase (EC 2.7.11.*) inhibitor
has_related_synonym: protein-serine/threonine kinase (EC 2.7.11.*) inhibitors
has_related_synonym: protein-serine/threonine kinase inhibitor
has_related_synonym: protein-serine/threonine kinase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.7.* (nucleotidyltransferase) inhibitor
type: Class
subclass of: EC 2.7.* (P-containing group transferase) inhibitor
definition: An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any nucleotidyltransferase (EC 2.7.7.*).
id: CHEBI:76815
has_related_synonym: EC 2.7.7.* (nucleotidyltransferase) inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of nucleotidyltransferases
has_related_synonym: inhibitor of nucleotidyltransferases (EC 2.7.7.*)
has_related_synonym: inhibitors of nucleotidyltransferases
has_related_synonym: inhibitors of nucleotidyltransferases (EC 2.7.7.*)
has_related_synonym: nucleotidyltransferase (EC 2.7.7.*) inhibitor
has_related_synonym: nucleotidyltransferase (EC 2.7.7.*) inhibitors
has_related_synonym: nucleotidyltransferase inhibitor
has_related_synonym: nucleotidyltransferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.8.* (transferases for other substituted phosphate groups) inhibitor
type: Class
subclass of: EC 2.7.* (P-containing group transferase) inhibitor
definition: An EC 2.7.* (P-containing group transferase) inhibitor that interferes with any enzyme in the EC 2.7.8.* (transferases for other substituted phosphate groups) category.
id: CHEBI:76816
has_related_synonym: EC 2.7.8.* (transferases for other substituted phosphate groups) inhibitors
has_related_synonym: EC 2.7.8.* inhibitor
has_related_synonym: EC 2.7.8.* inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.10.* (protein-tyrosine kinase) inhibitor
type: Class
subclass of: protein kinase inhibitor
subclass of: EC 2.7.* (P-containing group transferase) inhibitor
definition: An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any protein-tyrosine kinase (EC 2.7.10.*).
id: CHEBI:76817
has_related_synonym: EC 2.7.10.* (protein-tyrosine kinase) inhibitors
has_related_synonym: EC 2.7.10.* inhibitor
has_related_synonym: EC 2.7.10.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: protein-tyrosine kinase (EC 2.7.10.*) inhibitor
has_related_synonym: protein-tyrosine kinase (EC 2.7.10.*) inhibitors
has_related_synonym: protein-tyrosine kinase inhibitor
has_related_synonym: protein-tyrosine kinase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.3.* (phosphotransferases with a nitrogenous group as acceptor) inhibitor
type: Class
subclass of: EC 2.7.* (P-containing group transferase) inhibitor
definition: An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any phosphotransferases with a nitrogenous group as acceptor (EC 2.7.3.*).
id: CHEBI:76818
has_related_synonym: EC 2.7.3.* (phosphotransferases with a nitrogenous group as acceptor) inhibitors
has_related_synonym: EC 2.7.3.* inhibitor
has_related_synonym: EC 2.7.3.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: phosphotransferases with a nitrogenous group as acceptor (EC 2.7.3.*) inhibitor
has_related_synonym: phosphotransferases with a nitrogenous group as acceptor (EC 2.7.3.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.2.1.31 (beta-glucuronidase) inhibitor
type: Class
subclass of: EC 3.2.1.* (glycosidase) inhibitor
definition: An EC 3.2.1.* (glycosidase) inhibitor that interferes with the action of beta-glucuronidase (EC 3.2.1.31).
id: CHEBI:76822
has_related_synonym: EC 3.2.1.31 (beta-glucuronidase) inhibitors
has_related_synonym: EC 3.2.1.31 inhibitor
has_related_synonym: EC 3.2.1.31 inhibitors
database_cross_reference: Wikipedia:Beta-glucuronidase
has_related_synonym: beta-D-glucuronoside glucuronosohydrolase inhibitor
has_related_synonym: beta-D-glucuronoside glucuronosohydrolase inhibitors
has_related_synonym: beta-glucuronidase (EC 3.2.1.31) inhibitor
has_related_synonym: beta-glucuronidase (EC 3.2.1.31) inhibitors
has_related_synonym: beta-glucuronidase inhibitor
has_related_synonym: beta-glucuronidase inhibitors
has_related_synonym: beta-glucuronide glucuronohydrolase inhibitor
has_related_synonym: beta-glucuronide glucuronohydrolase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: exo-beta-D-glucuronidase inhibitor
has_related_synonym: exo-beta-D-glucuronidase inhibitors
has_related_synonym: glucuronidase inhibitor
has_related_synonym: glucuronidase inhibitors
has_related_synonym: ketodase inhibitor
has_related_synonym: ketodase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 6.3.1.* (acid-ammonia/amine ligase) inhibitor
type: Class
subclass of: EC 6.3.* (C-N bond-forming ligase) inhibitor
definition: An EC 6.3.* (C-N bond-forming ligase) inhibitor that interferes with the action of any acid-ammonia (or amine) ligase (EC 6.3.1.*).
id: CHEBI:76823
has_related_synonym: EC 6.3.1.* (acid-ammonia/amine ligase) inhibitors
has_related_synonym: EC 6.3.1.* inhibitor
has_related_synonym: EC 6.3.1.* inhibitors
has_related_synonym: acid-ammonia (or amine) ligase inhibitor
has_related_synonym: acid-ammonia (or amine) ligase inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 6.4.1.* (carboxylase) inhibitor
type: Class
subclass of: EC 6.4.* (C-C bond-forming ligase) inhibitor
definition: An EC 6.4.* (C-C bond-forming ligase) inhibitor that interferes with the action of a carboxylating enzyme (EC 6.4.1.*).
id: CHEBI:76824
has_related_synonym: EC 6.4.1.* (C-C bond forming ligase) inhibitor
has_related_synonym: EC 6.4.1.* (C-C bond forming ligase) inhibitors
has_related_synonym: EC 6.4.1.* (C-C bond-forming ligase) inhibitors
has_related_synonym: EC 6.4.1.* (carboxylase) inhibitors
has_related_synonym: EC 6.4.1.* inhibitor
has_related_synonym: EC 6.4.1.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of ligases forming C-C bonds
has_related_synonym: inhibitor of ligases forming C-C bonds (EC 6.4.1.*)
has_related_synonym: inhibitors of ligases forming C-C bonds
has_related_synonym: inhibitors of ligases forming C-C bonds (EC 6.4.1.*)
in_subset: 3 STAR
imported from: chebi.owl

EC 6.5.1.* (DNA/RNA repair enzymes) inhibitor
type: Class
subclass of: EC 6.5.* (phosphoric ester bond-forming ligase) inhibitor
definition: An EC 6.5.* (phosphoric ester bond-forming ligase) inhibitor that inhibits the activity of and DNA or RNA repair enzyme (EC 6.5.1.*).
id: CHEBI:76827
has_related_synonym: EC 6.5.1.* (DNA/RNA repair enzymes) inhibitors
has_related_synonym: EC 6.5.1.* inhibitor
has_related_synonym: EC 6.5.1.* inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 5.1.1.* (racemases acting on amino acids and derivatives) inhibitor
type: Class
subclass of: EC 5.1.* (racemase/epimerase) inhibitor
definition: An EC 5.1.* (racemase/epimerase) inhibitor that interferes with the function of any racemase acting on amino acids or their derivatives (EC 5.1.1.*).
id: CHEBI:76828
has_related_synonym: EC 5.1.1.* (racemases acting on amino acids and derivatives) inhibitors
has_related_synonym: EC 5.1.1.* inhibitor
has_related_synonym: EC 5.1.1.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of racemases acting on amino acids and derivatives
has_related_synonym: inhibitor of racemases acting on amino acids and derivatives (EC 5.1.1.*)
has_related_synonym: inhibitors of racemases acting on amino acids and derivatives
has_related_synonym: inhibitors of racemases acting on amino acids and derivatives (EC 5.1.1.*)
in_subset: 3 STAR
imported from: chebi.owl

EC 5.4.3.* (intramolecular transferase transferring amino groups) inhibitor
type: Class
subclass of: EC 5.4.* (intramolecular transferase) inhibitor
definition: An EC 5.4.* (intramolecular transferase) inhibitor that interferes with the activity of any intramolecular transferase transferring amino groups (EC 5.4.3.*).
id: CHEBI:76829
has_related_synonym: EC 5.4.3.* (intramolecular transferase transferring amino groups) inhibitors
has_related_synonym: EC 5.4.3.* inhibitor
has_related_synonym: EC 5.4.3.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of intramolecular transferase transferring amino groups
has_related_synonym: inhibitor of intramolecular transferase transferring amino groups (EC 5.4.3.*)
has_related_synonym: inhibitors of intramolecular transferase transferring amino groups
has_related_synonym: inhibitors of intramolecular transferase transferring amino groups (EC 5.4.3.*)
in_subset: 3 STAR
imported from: chebi.owl

EC 5.99.1.* (miscellaneous isomerase) inhibitor
type: Class
subclass of: EC 5.99.* (other isomerases) inhibitor
definition: An EC 5.99.* (other isomerases) inhibitor that interferes with the activity of any enzyme in the EC 5.99.1.* class.
id: CHEBI:76830
has_related_synonym: EC 5.99.1.* (miscellaneous isomerase) inhibitors
has_related_synonym: EC 5.99.1.* inhibitor
has_related_synonym: EC 5.99.1.* inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 4.4.1.* (C-S lyase) inhibitor
type: Class
subclass of: EC 4.4.* (C-S lyase) inhibitor
definition: An EC 4.4.* (C-S lyase) inhibitor that interferes with the activity of any enzyme in the EC 4.4.1.* category.
has_related_synonym: C-S lyase (EC 4.4.1.*) inhibitor
has_related_synonym: C-S lyase (EC 4.4.1.*) inhibitors
id: CHEBI:76831
has_related_synonym: EC 4.4.1.* (C-S lyase) inhibitors
has_related_synonym: EC 4.4.1.* inhibitor
has_related_synonym: EC 4.4.1.* inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 4.3.1.* (ammonia-lyase) inhibitor
type: Class
subclass of: EC 4.3.* (C-N lyase) inhibitor
definition: An EC 4.3.* (C-N lyase) inhibitor that interferes with the action of any ammonia-lyase (EC 4.3.1.*).
id: CHEBI:76832
has_related_synonym: EC 4.3.1.* (ammonia-lyase) inhibitors
has_related_synonym: EC 4.3.1.* (ammonia-lyases) inhibitor
has_related_synonym: EC 4.3.1.* (ammonia-lyases) inhibitors
has_related_synonym: EC 4.3.1.* inhibitor
has_related_synonym: EC 4.3.1.* inhibitors
has_related_synonym: ammonia-lyase (EC 4.3.1.*) inhibitor
has_related_synonym: ammonia-lyase (EC 4.3.1.*) inhibitors
has_related_synonym: ammonia-lyase inhibitor
has_related_synonym: ammonia-lyase inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 2.5.* (non-methyl-alkyl or aryl transferase) inhibitor
type: Class
subclass of: EC 2.* (transferase) inhibitor
definition: An EC 2.5.* (transferase) inhibitor that inhibits the action of any transferase that transfers an alkyl (other than methyl) or aryl group (EC 2.5.*).
id: CHEBI:76834
has_related_synonym: EC 2.5.* (non-methyl-alkyl or aryl transferase) inhibitors
has_related_synonym: EC 2.5.* inhibitor
has_related_synonym: EC 2.5.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: non-methyl-alkyl or aryl transferase (EC 2.5.*) inhibitor
has_related_synonym: non-methyl-alkyl or aryl transferase (EC 2.5.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor
type: Class
subclass of: EC 1.1.* (oxidoreductase acting on donor CH-OH group) inhibitor
definition: An EC 1.1.* (oxidoreductase acting on donor CH-OH group) inhibitor that uses NAD(+) or NADP(+) as acceptor (EC 1.1.1.*).
id: CHEBI:76835
has_related_synonym: EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+)acceptor) inhibitors
has_related_synonym: EC 1.1.1.* inhibitor
has_related_synonym: EC 1.1.1.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor (EC 1.1.1.*) inhibitor
has_related_synonym: oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor (EC 1.1.1.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.1.3.* (oxidoreductase acting on donor CH-OH group, oxygen as acceptor) inhibitor
type: Class
subclass of: EC 1.1.* (oxidoreductase acting on donor CH-OH group) inhibitor
definition: An EC 1.1.* (oxidoreductase acting on donor CH-OH group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.1.3.*).
id: CHEBI:76836
has_related_synonym: EC 1.1.3.* (oxidoreductase acting on donor CH-OH group, oxygen as acceptor) inhibitors
has_related_synonym: EC 1.1.3.* inhibitor
has_related_synonym: EC 1.1.3.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: oxidoreductase acting on donor CH-OH group, oxygen as acceptor (EC 1.1.3.*) inhibitor
has_related_synonym: oxidoreductase acting on donor CH-OH group, oxygen as acceptor (EC 1.1.3.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitor
type: Class
subclass of: EC 1.13.* [oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases)] inhibitor
definition: An EC 1.13.* [oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases)] inhibitor that inhibits the action of any oxidoreductase incorporating 2 atoms of oxygen (EC 1.13.11.*).
id: CHEBI:76837
has_related_synonym: EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitors
has_related_synonym: EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 atoms of oxygen) inhibitor
has_related_synonym: EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 atoms of oxygen) inhibitors
has_related_synonym: EC 1.13.11.* inhibitor
has_related_synonym: EC 1.13.11.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: oxidoreductase acting on single donors and incorporating 2 atoms of oxygen (EC 1.13.11.*) inhibitor
has_related_synonym: oxidoreductase acting on single donors and incorporating 2 atoms of oxygen (EC 1.13.11.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor
type: Class
subclass of: EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor
definition: An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any such enzyme incorporating one atom of oxygen and using reduced flavin or flavoprotein as donor (EC 1.14.14.*).
id: CHEBI:76838
has_related_synonym: EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitors
has_related_synonym: EC 1.14.14.* (oxidoreductase acting on paired donors, with incorporation of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor
has_related_synonym: EC 1.14.14.* (oxidoreductase acting on paired donors, with incorporation of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitors
has_related_synonym: EC 1.14.14.* inhibitor
has_related_synonym: EC 1.14.14.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: oxidoreductase acting on paired donors, with incorporation of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor (EC 1.14.14.*) inhibitor
has_related_synonym: oxidoreductase acting on paired donors, with incorporation of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor (EC 1.14.14.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.14.99.* (miscellaneous oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor
type: Class
subclass of: EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor
definition: An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any enzyme in the EC 1.14.99.* (miscellaneous) category.
id: CHEBI:76840
has_related_synonym: EC 1.14.99.* (miscellaneous oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitors
has_related_synonym: EC 1.14.99.* inhibitor
has_related_synonym: EC 1.14.99.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: miscellaneous oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.99.*) inhibitor
has_related_synonym: miscellaneous oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.99.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor
type: Class
subclass of: EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor
definition: An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any such enzyme incorporating one atom of oxygen and using NADH or NADPH as one donor (EC 1.14.13.*).
id: CHEBI:76841
has_related_synonym: EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitors
has_related_synonym: EC 1.14.13.* inhibitor
has_related_synonym: EC 1.14.13.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor (EC 1.14.13.*) inhibitor
has_related_synonym: oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor (EC 1.14.13.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.14.15.* (oxidoreductase acting on paired donors, with reduced Fe-S protein as one donor, incorporating 1 O atom) inhibitor
type: Class
subclass of: EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor
definition: An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any such enzyme with reduced iron-sulfur protein as one donor and incorporating one atom of oxygen (EC 1.14.15.*).
id: CHEBI:76843
has_related_synonym: EC 1.14.15.* (oxidoreductase acting on paired donors, with reduced Fe-S protein as one donor, incorporating 1 O atom) inhibitors
has_related_synonym: EC 1.14.15.* (oxidoreductase acting on paired donors, with reduced iron-sulfur protein as one donor, incorporating 1 atom of oxygen) inhibitor
has_related_synonym: EC 1.14.15.* (oxidoreductase acting on paired donors, with reduced iron-sulfur protein as one donor, incorporating 1 atom of oxygen) inhibitors
has_related_synonym: EC 1.14.15.* inhibitor
has_related_synonym: EC 1.14.15.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: oxidoreductase acting on paired donors, with reduced iron-sulfur protein as one donor, incorporating 1 atom of oxygen (EC 1.14.15.*) inhibitor
has_related_synonym: oxidoreductase acting on paired donors, with reduced iron-sulfur protein as one donor, incorporating 1 atom of oxygen (EC 1.14.15.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.14.18.* (oxidoreductase acting on paired donors, miscellaneous compound as one donor, incorporating 1 atom of oxygen) inhibitor
type: Class
subclass of: EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor
definition: An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any such enzyme using a miscellaneous compound as one donor and incorporating one atom of oxygen (EC 1.14.18.*).
id: CHEBI:76845
has_related_synonym: EC 1.14.18.* (oxidoreductase acting on paired donors, miscellaneous compound as one donor, incorporating 1 atom of oxygen) inhibitors
has_related_synonym: EC 1.14.18.* inhibitor
has_related_synonym: EC 1.14.18.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: oxidoreductase acting on paired donors, miscellaneous compound as one donor, incorporating 1 atom of oxygen (EC 1.14.18.*) inhibitor
has_related_synonym: oxidoreductase acting on paired donors, miscellaneous compound as one donor, incorporating 1 atom of oxygen (EC 1.14.18.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.14.16.* (oxidoreductase acting on paired donors, reduced pteridine as one donor, incorporating 1 atom of oxygen) inhibitor
type: Class
subclass of: EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor
definition: An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any such enzyme using reduced pteridine as one donor and incorporating one atom of oxygen (EC 1.14.16.*).
id: CHEBI:76847
has_related_synonym: EC 1.14.16.* (oxidoreductase acting on paired donors, reduced pteridine as one donor, incorporating 1 atom of oxygen) inhibitors
has_related_synonym: EC 1.14.16.* inhibitor
has_related_synonym: EC 1.14.16.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: oxidoreductase acting on paired donors, reduced pteridine as one donor, incorporating 1 atom of oxygen (EC 1.14.16.*) inhibitor
has_related_synonym: oxidoreductase acting on paired donors, reduced pteridine as one donor, incorporating 1 atom of oxygen (EC 1.14.16.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.17.4.* (oxidoreductase acting on CH or CH2 with a disulfide as acceptor) inhibitor
type: Class
subclass of: EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitor
definition: An EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitor that interferes with the activity of any such enzyme that uses a disulfide as acceptor (EC 1.17.4.*).
id: CHEBI:76848
has_related_synonym: EC 1.17.4.* (oxidoreductase acting on CH or CH2 with a disulfide as acceptor) inhibitors
has_related_synonym: EC 1.17.4.* inhibitor
has_related_synonym: EC 1.17.4.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: oxidoreductase acting on CH or CH2 with a disulfide as acceptor (EC 1.17.4.*) inhibitor
has_related_synonym: oxidoreductase acting on CH or CH2 with a disulfide as acceptor (EC 1.17.4.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.17.3.* (oxidoreductase acting on CH or CH2 with oxygen as acceptor) inhibitor
type: Class
subclass of: EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitor
definition: An EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitor that interferes with the function of any such enzyme that uses oxygen as acceptor (EC 1.17.3.*).
id: CHEBI:76850
has_related_synonym: EC 1.17.3.* (oxidoreductase acting on CH or CH2 with oxygen as acceptor) inhibitors
has_related_synonym: EC 1.17.3.* inhibitor
has_related_synonym: EC 1.17.3.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: oxidoreductase acting on CH or CH2 with oxygen as acceptor (EC 1.17.3.*) inhibitor
has_related_synonym: oxidoreductase acting on CH or CH2 with oxygen as acceptor (EC 1.17.3.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.2.1.* (oxidoreductase acting on donor aldehyde/oxo group with NAD(+) or NADP(+) as acceptor) inhibitor
type: Class
subclass of: EC 1.2.* (oxidoreductase acting on donor aldehyde/oxo group) inhibitor
definition: An EC 1.2.* (oxidoreductase acting on donor aldehyde/oxo group) inhibitor that interferes with the action of any such enzyme using NAD(+) or NADP(+) as acceptor (EC 1.2.1.*).
id: CHEBI:76852
has_related_synonym: EC 1.2.1.* (oxidoreductase acting on donor aldehyde/oxo group with NAD(+) or NADP(+) as acceptor) inhibitors
has_related_synonym: EC 1.2.1.* inhibitor
has_related_synonym: EC 1.2.1.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: oxidoreductase acting on donor aldehyde/oxo group with NAD(+) or NADP(+) as acceptor (EC 1.2.1.*) inhibitor
has_related_synonym: oxidoreductase acting on donor aldehyde/oxo group with NAD(+) or NADP(+) as acceptor (EC 1.2.1.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.2.3.* (oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor) inhibitor
type: Class
subclass of: EC 1.2.* (oxidoreductase acting on donor aldehyde/oxo group) inhibitor
definition: An EC 1.2.* (oxidoreductase acting on donor aldehyde/oxo group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.2.3.*).
id: CHEBI:76853
has_related_synonym: EC 1.2.3.* (oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor) inhibitors
has_related_synonym: EC 1.2.3.* inhibitor
has_related_synonym: EC 1.2.3.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor (EC 1.2.3.*) inhibitor
has_related_synonym: oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor (EC 1.2.3.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor
type: Class
subclass of: EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor
definition: An EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor that interferes with the action of any such enzyme using NAD(+) or NADP(+) as acceptor (EC 1.3.1.*).
id: CHEBI:76857
has_related_synonym: EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor with NAD(+) or NADP(+) as acceptor) inhibitor
has_related_synonym: EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor with NAD(+) or NADP(+) as acceptor) inhibitors
has_related_synonym: EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor, NAD(+) or NADP(+) as acceptor) inhibitor
has_related_synonym: EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor, NAD(+) or NADP(+) as acceptor) inhibitors
has_related_synonym: EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitors
has_related_synonym: EC 1.3.1.* inhibitor
has_related_synonym: EC 1.3.1.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: oxidoreductase acting on CH-CH group of donor with NAD(+) or NADP(+) as acceptor (EC 1.3.1.*) inhibitor
has_related_synonym: oxidoreductase acting on CH-CH group of donor with NAD(+) or NADP(+) as acceptor (EC 1.3.1.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.3.98.* (oxidoreductase acting on donor CH-CH group, with other, known, acceptors) inhibitor
type: Class
subclass of: EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor
definition: An EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor that interferes with the function of any such enzyme in the EC 1.3.98.* (with other, known, acceptors) category.
id: CHEBI:76858
has_related_synonym: EC 1.3.98.* (oxidoreductase acting on CH-CH group of donors, with other, known, acceptors) inhibitor
has_related_synonym: EC 1.3.98.* (oxidoreductase acting on CH-CH group of donors, with other, known, acceptors) inhibitors
has_related_synonym: EC 1.3.98.* (oxidoreductase acting on donor CH-CH group, with other, known, acceptors) inhibitors
has_related_synonym: EC 1.3.98.* inhibitor
has_related_synonym: EC 1.3.98.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: oxidoreductase acting on CH-CH group of donors, with other, known, acceptors (EC 1.3.98.*) inhibitor
has_related_synonym: oxidoreductase acting on CH-CH group of donors, with other, known, acceptors (EC 1.3.98.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.3.99.* (oxidoreductase acting on donor CH-CH group, with other acceptors) inhibitor
type: Class
subclass of: EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor
definition: An EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor that interferes with the function of any such enzyme in the EC 1.3.98.* (with other acceptors) category.
id: CHEBI:76859
has_related_synonym: EC 1.3.99.* (oxidoreductase acting on donor CH-CH group with other acceptors) inhibitors
has_related_synonym: EC 1.3.99.* (oxidoreductase acting on donor CH-CH group, with other acceptors) inhibitors
has_related_synonym: EC 1.3.99.* inhibitor
has_related_synonym: EC 1.3.99.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: oxidoreductase acting on donor CH-CH group with other acceptors (EC 1.3.99.*) inhibitor
has_related_synonym: oxidoreductase acting on donor CH-CH group with other acceptors (EC 1.3.99.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.3.3.* (oxidoreductase acting on donor CH-CH group, oxygen as acceptor) inhibitor
type: Class
subclass of: EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor
definition: An EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.3.3.*).
id: CHEBI:76860
has_related_synonym: EC 1.3.3.* (oxidoreductase acting on donor CH-CH group with oxygen as acceptor) inhibitor
has_related_synonym: EC 1.3.3.* (oxidoreductase acting on donor CH-CH group with oxygen as acceptor) inhibitors
has_related_synonym: EC 1.3.3.* (oxidoreductase acting on donor CH-CH group, oxygen as acceptor) inhibitors
has_related_synonym: EC 1.3.3.* inhibitor
has_related_synonym: EC 1.3.3.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: oxidoreductase acting on donor CH-CH group with oxygen as acceptor (EC 1.3.3.*) inhibitor
has_related_synonym: oxidoreductase acting on donor CH-CH group with oxygen as acceptor (EC 1.3.3.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor
type: Class
subclass of: EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor
definition: An EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.4.3.*).
id: CHEBI:76861
has_related_synonym: EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitors
has_related_synonym: EC 1.4.3.* inhibitor
has_related_synonym: EC 1.4.3.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor (EC 1.4.3.*) inhibitor
has_related_synonym: oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor (EC 1.4.3.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.4.4.* (oxidoreductase acting on donor CH-NH2 group, a disulfide as acceptor) inhibitor
type: Class
subclass of: EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor
definition: An EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor that interferes with the action of any such enzyme using a disulfide as acceptor (EC 1.4.4.*).
id: CHEBI:76862
has_related_synonym: EC 1.4.4.* (oxidoreductase acting on donor CH-NH2 group, a disulfide as acceptor) inhibitors
has_related_synonym: EC 1.4.4.* inhibitor
has_related_synonym: EC 1.4.4.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: oxidoreductase acting on donor CH-NH2 group, a disulfide as acceptor (EC 1.4.4.*) inhibitor
has_related_synonym: oxidoreductase acting on donor CH-NH2 group, a disulfide as acceptor (EC 1.4.4.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor) inhibitor
type: Class
subclass of: EC 1.5.* (oxidoreductase acting on donor CH-NH group) inhibitor
definition: An EC 1.5.* (oxidoreductase acting on donor CH-NH group) inhibitor that interferes with the action of any such enzyme using NAD(+) or NADP(+) as acceptor (EC 1.5.1.*).
id: CHEBI:76863
has_related_synonym: EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor) inhibitors
has_related_synonym: EC 1.5.1.* inhibitor
has_related_synonym: EC 1.5.1.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor (EC 1.5.1.*) inhibitor
has_related_synonym: oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor (EC 1.5.1.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.6.5.* (oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor) inhibitor
type: Class
subclass of: EC 1.6.* (oxidoreductase acting on NADH or NADPH) inhibitor
definition: An EC 1.6.* (oxidoreductase acting on NADH or NADPH) inhibitor that interferes with the action of any such enzyme using a quinone or similar as acceptor (EC 1.6.5.*).
id: CHEBI:76866
has_related_synonym: EC 1.6.5.* (oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor) inhibitors
has_related_synonym: EC 1.6.5.* inhibitor
has_related_synonym: EC 1.6.5.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor (EC 1.6.5.*) inhibitor
has_related_synonym: oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor (EC 1.6.5.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.6.3.* (oxidoreductase acting on NADH or NADPH with oxygen as acceptor) inhibitor
type: Class
subclass of: EC 1.6.* (oxidoreductase acting on NADH or NADPH) inhibitor
definition: An EC 1.6.* (oxidoreductase acting on NADH or NADPH) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.6.3.*).
id: CHEBI:76867
has_related_synonym: EC 1.6.3.* (oxidoreductase acting on NADH or NADPH with oxygen as acceptor) inhibitors
has_related_synonym: EC 1.6.3.* inhibitor
has_related_synonym: EC 1.6.3.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: oxidoreductase acting on NADH or NADPH with oxygen as acceptor (EC 1.6.3.*) inhibitor
has_related_synonym: oxidoreductase acting on NADH or NADPH with oxygen as acceptor (EC 1.6.3.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD(+) or NADP(+) as acceptor) inhibitor
type: Class
subclass of: EC 1.8.* (oxidoreductase acting on sulfur group of donors) inhibitor
definition: An EC 1.8.* (oxidoreductase acting on sulfur group of donors) inhibitor that interferes with the action of any such enzyme using NAD(+) or NADP(+) as acceptor (EC 1.8.1.*).
id: CHEBI:76869
has_related_synonym: EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD(+) or NADP(+) as acceptor) inhibitors
has_related_synonym: EC 1.8.1.* inhibitor
has_related_synonym: EC 1.8.1.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: oxidoreductase acting on sulfur group of donors, NAD(+) or NADP(+) as acceptor (EC 1.8.1.*) inhibitor
has_related_synonym: oxidoreductase acting on sulfur group of donors, NAD(+) or NADP(+) as acceptor (EC 1.8.1.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.9.3.* (oxidoreductase acting on donor heme group, oxygen as acceptor) inhibitor
type: Class
subclass of: EC 1.9.* (oxidoreductase acting on donor heme group) inhibitor
definition: An EC 1.9.* (oxidoreductase acting on donor heme group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.9.3.*).
id: CHEBI:76870
has_related_synonym: EC 1.9.3.* (oxidoreductase acting on donor heme group, oxygen as acceptor) inhibitors
has_related_synonym: EC 1.9.3.* inhibitor
has_related_synonym: EC 1.9.3.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: oxidoreductase acting on donor heme group, oxygen as acceptor (EC 1.9.3.*) inhibitor
has_related_synonym: oxidoreductase acting on donor heme group, oxygen as acceptor (EC 1.9.3.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.1.1.* (methyltransferases) inhibitor
type: Class
subclass of: EC 2.1.* (C1-transferase) inhibitor
definition: An EC 2.1.* (C1-transferase) inhibitor that interferes with the action of any methyltransferase (EC 2.1.1.*).
id: CHEBI:76871
has_related_synonym: EC 2.1.1.* (methyltransferase) inhibitor
has_related_synonym: EC 2.1.1.* (methyltransferase) inhibitors
has_related_synonym: EC 2.1.1.* (methyltransferases) inhibitors
has_related_synonym: EC 2.1.1.* inhibitor
has_related_synonym: EC 2.1.1.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: methyltransferase (EC 2.1.1.*) inhibitor
has_related_synonym: methyltransferase (EC 2.1.1.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor
type: Class
subclass of: EC 2.1.* (C1-transferase) inhibitor
definition: An EC 2.1.* (C1-transferase) inhibitor that interferes with the action of any hydroxymethyl-, formyl- and related transferase (EC 2.1.2.*).
id: CHEBI:76874
has_related_synonym: EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitors
has_related_synonym: EC 2.1.2.* inhibitor
has_related_synonym: EC 2.1.2.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: hydroxymethyl-, formyl- and related transferases (EC 2.1.2.*) inhibitor
has_related_synonym: hydroxymethyl-, formyl- and related transferases (EC 2.1.2.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.2.1.* (transketolase/transaldolase) inhibitor
type: Class
subclass of: EC 2.2.* (aldehyde or ketone transferase) inhibitor
definition: An EC 2.2.* (aldehyde or ketone transferase) inhibitor that interferes with the action of any (transketolase or transaldolase (EC 2.2.1.*).
id: CHEBI:76876
has_related_synonym: EC 2.2.1.* (transketolase/transaldolase) inhibitors
has_related_synonym: EC 2.2.1.* (transketolases and transaldolases) inhibitor
has_related_synonym: EC 2.2.1.* (transketolases and transaldolases) inhibitors
has_related_synonym: EC 2.2.1.* inhibitor
has_related_synonym: EC 2.2.1.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: transketolase/transaldolase (EC 2.2.1.*) inhibitor
has_related_synonym: transketolase/transaldolase (EC 2.2.1.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.3.2.* (aminoacyltransferase) inhibitor
type: Class
subclass of: EC 2.3.* (acyltransferase) inhibitor
definition: An EC 2.3.* (acyltransferase) inhibitor that interferes with the action of any aminoacyltransferase (EC 2.3.2.*).
id: CHEBI:76877
has_related_synonym: EC 2.3.2.* (aminoacyltransferase) inhibitors
has_related_synonym: EC 2.3.2.* inhibitor
has_related_synonym: EC 2.3.2.* inhibitors
has_related_synonym: aminoacyltransferase (EC 2.3.2.*) inhibitor
has_related_synonym: aminoacyltransferase (EC 2.3.2.*) inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor
type: Class
subclass of: EC 2.3.* (acyltransferase) inhibitor
definition: An EC 2.3.* (acyltransferase) inhibitor that inhibits the action of any acyltransferase transferring groups other than amino-acyl groups (EC 2.3.1.*).
id: CHEBI:76878
has_related_synonym: EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitors
has_related_synonym: EC 2.3.1.* inhibitor
has_related_synonym: EC 2.3.1.* inhibitors
has_related_synonym: acyltransferase transferring other than amino-acyl group EC 2.3.1.* inhibitor
has_related_synonym: acyltransferase transferring other than amino-acyl group EC 2.3.1.* inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 2.6.1.* (transaminase) inhibitor
type: Class
subclass of: EC 2.6.* (nitrogenous group transferase) inhibitor
definition: An EC 2.6.* (nitrogenous group transferase) inhibitor that inhibits the action of any transaminase (EC 2.6.1.*).
id: CHEBI:76879
has_related_synonym: EC 2.6.1.* (transaminase) inhibitors
has_related_synonym: EC 2.6.1.* inhibitor
has_related_synonym: EC 2.6.1.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: transaminase (EC 2.6.1.*) inhibitor
has_related_synonym: transaminase (EC 2.6.1.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor
type: Class
subclass of: EC 2.7.* (P-containing group transferase) inhibitor
definition: An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any phosphotransferase with an alcohol group as acceptor (EC 2.7.1.*).
id: CHEBI:76881
has_related_synonym: EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitors
has_related_synonym: EC 2.7.1.* inhibitor
has_related_synonym: EC 2.7.1.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: phosphotransferases with an alcohol group as acceptor (EC 2.7.1.*) inhibitor
has_related_synonym: phosphotransferases with an alcohol group as acceptor (EC 2.7.1.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.4.99.* (glycosyltransferases transferring other glycosyl groups) inhibitor
type: Class
subclass of: EC 2.4.* (glycosyltransferase) inhibitor
definition: An EC 2.4.* (glycosyltransferase) inhibitor that interferes with the activity of any glycosyltransferase in the EC 2.4.99.* (transferring other glycosyl groups) category.
id: CHEBI:76882
has_related_synonym: EC 2.4.99.* (glycosyltransferases transferring other glycosyl groups) inhibitors
has_related_synonym: EC 2.4.99.* inhibitor
has_related_synonym: EC 2.4.99.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: glycosyltransferases transferring other glycosyl groups (EC 2.4.99.*) inhibitor
has_related_synonym: glycosyltransferases transferring other glycosyl groups (EC 2.4.99.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.11.1.* (hydrolases acting on C-P bonds of phosphono-acetaldehyde, -acetate, or -pyruvate) inhibitor
type: Class
subclass of: EC 3.11.* (hydrolases acting on C-P bonds) inhibitor
definition: An EC 3.11.* (hydrolases acting on C-P bonds) inhibitor that interferes with the activity of any phosphonoacetaldehyde, phosphonoacetate, or phosphonopyruvate hydrolase (EC 3.11.1.*).
id: CHEBI:76883
has_related_synonym: EC 3.11.1.* (hydrolases acting on C-P bonds of phosphono-acetaldehyde, -acetate, or -pyruvate) inhibitors
has_related_synonym: EC 3.11.1.* inhibitor
has_related_synonym: EC 3.11.1.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: hydrolases acting on C-P bonds of phosphono-acetaldehyde, -acetate, or -pyruvate (EC 3.11.1.*) inhibitor
has_related_synonym: hydrolases acting on C-P bonds of phosphono-acetaldehyde, -acetate, or -pyruvate (EC 3.11.1.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.23.* (aspartic endopeptidase) inhibitor
type: Class
subclass of: EC 3.4.* (hydrolases acting on peptide bond) inhibitor
definition: An EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes with the action of any aspartic endopeptidase (EC 3.4.23.*).
id: CHEBI:76885
has_related_synonym: EC 3.4.23.* (aspartic endopeptidase) inhibitors
has_related_synonym: EC 3.4.23.* (aspartic endopeptidases) inhibitor
has_related_synonym: EC 3.4.23.* (aspartic endopeptidases) inhibitors
has_related_synonym: EC 3.4.23.* inhibitor
has_related_synonym: EC 3.4.23.* inhibitors
has_related_synonym: aspartic endopeptidase (EC 3.4.23.*) inhibitor
has_related_synonym: aspartic endopeptidase (EC 3.4.23.*) inhibitors
has_related_synonym: aspartic endopeptidases (EC 3.4.23.*) inhibitor
has_related_synonym: aspartic endopeptidases (EC 3.4.23.*) inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.11.14 (cytosol alanyl aminopeptidase) inhibitor
type: Class
subclass of: EC 3.4.11.* (aminopeptidase) inhibitor
definition: An EC 3.4.11.* (aminopeptidase) inhibitor that interferes with the action of cytosol alanyl aminopeptidase (EC 3.4.11.14).
id: CHEBI:76891
has_related_synonym: EC 3.4.11.14 (cytosol alanyl aminopeptidase) inhibitors
has_related_synonym: EC 3.4.11.14 inhibitor
has_related_synonym: EC 3.4.11.14 inhibitors
database_cross_reference: Wikipedia:Cytosol_alanyl_aminopeptidase
has_related_synonym: alanine aminopeptidase inhibitor
has_related_synonym: alanine aminopeptidase inhibitors
has_related_synonym: aminopolypeptidase inhibitor
has_related_synonym: aminopolypeptidase inhibitors
has_related_synonym: arylamidase inhibitor
has_related_synonym: arylamidase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: cytosol alanyl aminopeptidase (EC 3.4.11.14) inhibitor
has_related_synonym: cytosol alanyl aminopeptidase (EC 3.4.11.14) inhibitors
has_related_synonym: cytosol alanyl aminopeptidase inhibitor
has_related_synonym: cytosol alanyl aminopeptidase inhibitors
has_related_synonym: cytosol aminopeptidase III inhibitor
has_related_synonym: cytosol aminopeptidase III inhibitors
has_related_synonym: human liver aminopeptidase inhibitor
has_related_synonym: human liver aminopeptidase inhibitors
has_related_synonym: puromycin-sensitive aminopeptidase inhibitor
has_related_synonym: puromycin-sensitive aminopeptidase inhibitors
has_related_synonym: soluble alanyl aminopeptidase inhibitor
has_related_synonym: soluble alanyl aminopeptidase inhibitors
has_related_synonym: thiol-activated aminopeptidase inhibitor
has_related_synonym: thiol-activated aminopeptidase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.14.2 (dipeptidyl-peptidase II) inhibitor
type: Class
subclass of: EC 3.4.14.* (dipeptidyl- and tripeptidyl-peptidases) inhibitor
definition: An EC 3.4.14.* (dipeptidyl- and tripeptidyl-peptidases) inhibitor that interferes with the action of dipeptidyl-peptidase II (EC 3.4.14.2).
id: CHEBI:76893
has_related_synonym: DAP II inhibitor
has_related_synonym: DAP II inhibitors
has_related_synonym: EC 3.4.14.2 (dipeptidyl-peptidase II) inhibitors
has_related_synonym: EC 3.4.14.2 inhibitor
has_related_synonym: EC 3.4.14.2 inhibitors
has_related_synonym: carboxytripeptidase inhibitor
has_related_synonym: carboxytripeptidase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: dipeptidyl aminopeptidase II inhibitor
has_related_synonym: dipeptidyl aminopeptidase II inhibitors
has_related_synonym: dipeptidyl arylamidase II inhibitor
has_related_synonym: dipeptidyl arylamidase II inhibitors
has_related_synonym: dipeptidyl peptidase II inhibitor
has_related_synonym: dipeptidyl peptidase II inhibitors
has_related_synonym: dipeptidyl(amino)peptidase II inhibitor
has_related_synonym: dipeptidyl(amino)peptidase II inhibitors
has_related_synonym: dipeptidyl-peptidase II (EC 3.4.14.2) inhibitor
has_related_synonym: dipeptidyl-peptidase II (EC 3.4.14.2) inhibitors
has_related_synonym: dipeptidyl-peptidase II inhibitor
has_related_synonym: dipeptidyl-peptidase II inhibitors
has_related_synonym: dipeptidylarylamidase inhibitor
has_related_synonym: dipeptidylarylamidase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor
type: Class
subclass of: EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor
definition: An EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor that interferes with the action of any such enzyme that catalyses transmembrane movement of substances (EC 3.6.3.*).
id: CHEBI:76895
has_related_synonym: EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitors
has_related_synonym: EC 3.6.3.* inhibitor
has_related_synonym: EC 3.6.3.* inhibitors
has_related_synonym: acid anhydride hydrolase catalysing transmembrane movement of substances (EC 3.6.3.*) inhibitor
has_related_synonym: acid anhydride hydrolase catalysing transmembrane movement of substances (EC 3.6.3.*) inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 1.14.14.1 (unspecific monooxygenase) inhibitor
type: Class
subclass of: EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor
definition: An EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor that interferes with the action of an unspecified monooxygenase (EC 1.14.14.1).
id: CHEBI:76898
has_related_synonym: EC 1.14.14.1 (unspecific monooxygenase) inhibitors
has_related_synonym: EC 1.14.14.1 inhibitor
has_related_synonym: EC 1.14.14.1 inhibitors
has_related_synonym: aryl hydrocarbon hydroxylase inhibitor
has_related_synonym: aryl hydrocarbon hydroxylase inhibitors
has_related_synonym: aryl-4-monooxygenase inhibitor
has_related_synonym: aryl-4-monooxygenase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: flavoprotein monooxygenase inhibitor
has_related_synonym: flavoprotein monooxygenase inhibitors
has_related_synonym: flavoprotein-linked monooxygenase inhibitor
has_related_synonym: flavoprotein-linked monooxygenase inhibitors
has_related_synonym: microsomal P-450 inhibitor
has_related_synonym: microsomal P-450 inhibitors
has_related_synonym: microsomal monooxygenase inhibitor
has_related_synonym: microsomal monooxygenase inhibitors
has_related_synonym: substrate,reduced-flavoprotein:oxygen oxidoreductase (RH-hydroxylating or -epoxidising) inhibitor
has_related_synonym: substrate,reduced-flavoprotein:oxygen oxidoreductase (RH-hydroxylating or -epoxidising) inhibitors
has_related_synonym: unspecific monooxygenase (EC 1.14.14.1) inhibitor
has_related_synonym: unspecific monooxygenase (EC 1.14.14.1) inhibitors
has_related_synonym: unspecific monooxygenase inhibitor
has_related_synonym: unspecific monooxygenase inhibitors
has_related_synonym: xenobiotic monooxygenase inhibitor
has_related_synonym: xenobiotic monooxygenase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor
type: Class
subclass of: EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor
definition: An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the function of any such enzyme using 2-oxoglutarate as one donor and incorporating one atom each of oxygen into both donors (EC 1.14.11.*).
id: CHEBI:76902
has_related_synonym: EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitors
has_related_synonym: EC 1.14.11.* (oxidoreductase acting on paired donors, with 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors) inhibitor
has_related_synonym: EC 1.14.11.* (oxidoreductase acting on paired donors, with 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors) inhibitors
has_related_synonym: EC 1.14.11.* inhibitor
has_related_synonym: EC 1.14.11.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors (EC 1.14.11.*) inhibitor
has_related_synonym: oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors (EC 1.14.11.*) inhibitors
has_related_synonym: oxidoreductase acting on paired donors, with 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors (EC 1.14.11.*) inhibitor
has_related_synonym: oxidoreductase acting on paired donors, with 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors (EC 1.14.11.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 4.1.1.* (carboxy-lyase) inhibitor
type: Class
subclass of: EC 4.1.* (C-C lyase) inhibitor
definition: An EC 4.1.* (C-C lyase) inhibitor that interferes with the action of any carboxy-lyase (EC 4.1.1.*).
id: CHEBI:76906
has_related_synonym: EC 4.1.1.* (carboxy-lyase) inhibitors
has_related_synonym: EC 4.1.1.* inhibitor
has_related_synonym: EC 4.1.1.* inhibitors
has_related_synonym: carboxy-lyase (EC 4.1.1.*) inhibitor
has_related_synonym: carboxy-lyase (EC 4.1.1.*) inhibitors
has_related_synonym: carboxy-lyases (EC 4.1.1.*) inhibitor
has_related_synonym: carboxy-lyases (EC 4.1.1.*) inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 4.2.1.* (hydro-lyases) inhibitor
type: Class
subclass of: EC 4.2.* (C-O lyase) inhibitor
definition: An EC 4.2.* (C-O lyase) inhibitor that interferes with the action of any hydro-lyase (EC 4.2.1.*).
id: CHEBI:76907
has_related_synonym: EC 4.2.1.* (hydro-lyase) inhibitor
has_related_synonym: EC 4.2.1.* (hydro-lyase) inhibitors
has_related_synonym: EC 4.2.1.* (hydro-lyases) inhibitors
has_related_synonym: EC 4.2.1.* inhibitor
has_related_synonym: EC 4.2.1.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: hydro-lyase (EC 4.2.1.*) inhibitor
has_related_synonym: hydro-lyase (EC 4.2.1.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

hyperglycemic agent
type: Class
subclass of: drug
definition: A drug which increases the blood glucose level.
id: CHEBI:76916
has_obo_namespace: chebi_ontology
has_related_synonym: diabetes inducer
has_related_synonym: hyperglycemic agents
in_subset: 3 STAR
imported from: chebi.owl

EC 1.1.3.9 (galactose oxidase) inhibitor
type: Class
subclass of: EC 1.1.3.* (oxidoreductase acting on donor CH-OH group, oxygen as acceptor) inhibitor
definition: An EC 1.1.3.* (oxidoreductase acting on donor CH-OH group, oxygen as acceptor) inhibitor that interferes with the action of galactose oxidase (EC 1.1.3.9).
id: CHEBI:76920
has_related_synonym: D-galactose oxidase inhibitor
has_related_synonym: D-galactose oxidase inhibitors
has_related_synonym: D-galactose:oxygen 6-oxidoreductase inhibitor
has_related_synonym: D-galactose:oxygen 6-oxidoreductase inhibitors
has_related_synonym: EC 1.1.3.9 (galactose oxidase) inhibitors
has_related_synonym: EC 1.1.3.9 inhibitor
has_related_synonym: EC 1.1.3.9 inhibitors
database_cross_reference: Wikipedia:Galactose_oxidase
has_related_synonym: beta-galactose oxidase inhibitor
has_related_synonym: beta-galactose oxidase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: galactose oxidase inhibitor
has_related_synonym: galactose oxidase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

plant metabolite
type: Class
subclass of: eukaryotic metabolite
definition: Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
has_alternative_id: CHEBI:75766
id: CHEBI:76924
has_alternative_id: CHEBI:76925
has_obo_namespace: chebi_ontology
has_related_synonym: plant metabolites
has_related_synonym: plant secondary metabolites
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.13.19 (membrane dipeptidase) inhibitor
type: Class
subclass of: EC 3.4.13.* (dipeptidase) inhibitor
definition: An EC 3.4.13.* (dipeptidase) inhibitor that interferes with the action of membrane dipeptidase (EC 3.4.13.19).
id: CHEBI:76926
has_related_synonym: DPH I inhibitors
has_related_synonym: EC 3.4.13.19 (membrane dipeptidase) inhibitors
has_related_synonym: EC 3.4.13.19 inhibitor
has_related_synonym: EC 3.4.13.19 inhibitors
has_related_synonym: MDP inhibitors
has_related_synonym: aminodipeptidase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: dehydropeptidase I (DPH I) inhibitors
has_related_synonym: dehydropeptidase I inhibitors
has_related_synonym: dipeptidase inhibitors
has_related_synonym: dipeptide hydrolase inhibitors
has_related_synonym: dipeptidyl hydrolase inhibitors
has_related_synonym: glycosyl-phosphatidylinositol-anchored renal dipeptidase inhibitors
has_related_synonym: membrane dipeptidase (EC 3.4.13.19) inhibitor
has_related_synonym: membrane dipeptidase (EC 3.4.13.19) inhibitors
has_related_synonym: membrane dipeptidase inhibitor
has_related_synonym: membrane dipeptidase inhibitors
has_related_synonym: microsomal dipeptidase inhibitors
has_related_synonym: nonspecific dipeptidase inhibitors
has_related_synonym: renal dipeptidase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

pathway inhibitor
type: Class
subclass of: enzyme inhibitor
definition: An enzyme inhibitor that interferes with one or more steps in a metabolic pathway.
id: CHEBI:76932
has_obo_namespace: chebi_ontology
has_related_synonym: metabolic pathway inhibitor
has_related_synonym: metabolic pathway inhibitors
has_related_synonym: pathway inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.6.4.* (hydrolases acting on ATP; involved in cellular and subcellular movement) inhibitor
type: Class
subclass of: EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor
definition: An EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor that interferes with the action of any such enzyme acting on ATP and involved in cellular and subcellular movement (EC 3.6.4.*).
id: CHEBI:76938
has_related_synonym: EC 3.6.4.* (hydrolase acting on ATP; involved in cellular and subcellular movement) inhibitor
has_related_synonym: EC 3.6.4.* (hydrolase acting on ATP; involved in cellular and subcellular movement) inhibitors
has_related_synonym: EC 3.6.4.* (hydrolases acting on ATP; involved in cellular and subcellular movement) inhibitors
has_related_synonym: EC 3.6.4.* inhibitor
has_related_synonym: EC 3.6.4.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: hydrolases acting on ATP; involved in cellular and subcellular movement (EC 3.6.4.*) inhibitor
has_related_synonym: hydrolases acting on ATP; involved in cellular and subcellular movement (EC 3.6.4.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.6.4.10 (non-chaperonin molecular chaperone ATPase) inhibitor
type: Class
subclass of: EC 3.6.4.* (hydrolases acting on ATP; involved in cellular and subcellular movement) inhibitor
has_related_synonym: ATP phosphohydrolase (polypeptide-polymerising) inhibitor
has_related_synonym: ATP phosphohydrolase (polypeptide-polymerising) inhibitors
has_related_synonym: ATP phosphohydrolase (polypeptide-polymerizing) inhibitor
has_related_synonym: ATP phosphohydrolase (polypeptide-polymerizing) inhibitors
definition: An EC 3.6.4.* (hydrolases acting on ATP; involved in cellular and subcellular movement) inhibitor that interferes with the action of a non-chaperonin molecular chaperone ATPase (EC 3.6.4.10).
id: CHEBI:76939
has_related_synonym: EC 3.6.4.10 (non-chaperonin molecular chaperone ATPase) inhibitors
has_related_synonym: EC 3.6.4.10 inhibitor
has_related_synonym: EC 3.6.4.10 inhibitors
database_cross_reference: Wikipedia:Non-chaperonin_molecular_chaperone_ATPase
has_obo_namespace: chebi_ontology
has_related_synonym: molecular chaperone Hsc70 ATPase inhibitor
has_related_synonym: molecular chaperone Hsc70 ATPase inhibitors
has_related_synonym: non-chaperonin molecular chaperone ATPase (EC 3.6.4.10) inhibitor
has_related_synonym: non-chaperonin molecular chaperone ATPase (EC 3.6.4.10) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.21.4 (trypsin) inhibitor
type: Class
subclass of: EC 3.4.21.* (serine endopeptidase) inhibitor
definition: An EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of trypsin (EC 3.4.21.4).
id: CHEBI:76940
has_related_synonym: EC 3.4.21.4 (trypsin) inhibitors
has_related_synonym: EC 3.4.21.4 inhibitor
has_related_synonym: EC 3.4.21.4 inhibitors
database_cross_reference: Wikipedia:Trypsin_inhibitor
has_related_synonym: alpha-trypsin inhibitor
has_related_synonym: alpha-trypsin inhibitors
has_related_synonym: beta-trypsin inhibitor
has_related_synonym: beta-trypsin inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: cocoonase inhibitor
has_related_synonym: cocoonase inhibitors
has_related_synonym: parenzyme inhibitor
has_related_synonym: parenzyme inhibitors
has_related_synonym: parenzymol inhibitor
has_related_synonym: parenzymol inhibitors
has_related_synonym: pseudotrypsin inhibitor
has_related_synonym: pseudotrypsin inhibitors
has_related_synonym: sperm receptor hydrolase inhibitor
has_related_synonym: sperm receptor hydrolase inhibitors
has_related_synonym: tripcellim inhibitor
has_related_synonym: tripcellim inhibitors
has_related_synonym: trypsin (EC 3.4.21.4) inhibitor
has_related_synonym: trypsin (EC 3.4.21.4) inhibitors
has_related_synonym: trypsin inhibitor
has_related_synonym: trypsin inhibitors
has_related_synonym: tryptar inhibitor
has_related_synonym: tryptar inhibitors
has_related_synonym: tryptase inhibitor
has_related_synonym: tryptase inhibitors
has_related_synonym: trypure inhibitor
has_related_synonym: trypure inhibitors
in_subset: 3 STAR
imported from: chebi.owl

fungal metabolite
type: Class
subclass of: eukaryotic metabolite
definition: Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds.
has_alternative_id: CHEBI:75765
id: CHEBI:76946
has_alternative_id: CHEBI:76947
has_obo_namespace: chebi_ontology
has_related_synonym: fungal metabolites
in_subset: 3 STAR
imported from: chebi.owl

Aspergillus metabolite
type: Class
subclass of: fungal metabolite
definition: Any fungal metabolite produced during a metabolic reaction in the mould, Aspergillus.
has_related_synonym: Aspergillus metabolites
has_alternative_id: CHEBI:75864
id: CHEBI:76956
has_alternative_id: CHEBI:76958
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

Chaetomium metabolite
type: Class
subclass of: fungal metabolite
definition: Any fungal metabolite produced during a metabolic reaction in the mould, Chaetomium.
has_alternative_id: CHEBI:75916
id: CHEBI:76960
has_alternative_id: CHEBI:76961
has_related_synonym: Chaetomium metabolites
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

Penicillium metabolite
type: Class
subclass of: fungal metabolite
definition: Any fungal metabolite produced during a metabolic reaction in Penicillium.
has_alternative_id: CHEBI:76205
has_alternative_id: CHEBI:76963
id: CHEBI:76964
has_related_synonym: Penicillium metabolites
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

human xenobiotic metabolite
type: Class
subclass of: xenobiotic metabolite
subclass of: human metabolite
definition: Any human metabolite produced by metabolism of a xenobiotic compound in humans.
id: CHEBI:76967
has_obo_namespace: chebi_ontology
has_related_synonym: human xenobiotic metabolites
in_subset: 3 STAR
imported from: chebi.owl

fungal xenobiotic metabolite
type: Class
subclass of: xenobiotic metabolite
subclass of: fungal metabolite
definition: Any fungal metabolite produced by metabolism of a xenobiotic compound in fungi.
id: CHEBI:76968
has_obo_namespace: chebi_ontology
has_related_synonym: fungal xenobiotic metabolites
in_subset: 3 STAR
imported from: chebi.owl

bacterial metabolite
type: Class
subclass of: prokaryotic metabolite
definition: Any prokaryotic metabolite produced during a metabolic reaction in bacteria.
has_alternative_id: CHEBI:75760
id: CHEBI:76969
has_alternative_id: CHEBI:76970
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

Escherichia coli metabolite
type: Class
subclass of: bacterial metabolite
definition: Any bacterial metabolite produced during a metabolic reaction in Escherichia coli.
id: CHEBI:76971
has_related_synonym: E.coli metabolite
has_related_synonym: E.coli metabolites
has_related_synonym: Escherichia coli metabolites
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

Streptococcus pneumoniae metabolite
type: Class
subclass of: bacterial metabolite
definition: Any bacterial metabolite produced during a metabolic reaction in Streptococcus pneumoniae.
has_alternative_id: CHEBI:75789
id: CHEBI:76973
has_alternative_id: CHEBI:76974
has_related_synonym: S. pneumoniae metabolite
has_related_synonym: S. pneumoniae metabolites
has_related_synonym: S. pneumoniae secondary metabolite
has_related_synonym: S. pneumoniae secondary metabolites
has_related_synonym: Streptococcus pneumoniae metabolites
has_related_synonym: Streptococcus pneumoniae secondary metabolites
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

bacterial xenobiotic metabolite
type: Class
subclass of: xenobiotic metabolite
subclass of: bacterial metabolite
definition: Any bacterial metabolite produced by metabolism of a xenobiotic compound in bacteria.
id: CHEBI:76976
has_related_synonym: bacterial xenobiotic metabolites
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

corticotropin-releasing factor receptor antagonist
type: Class
subclass of: hormone antagonist
definition: A hormone antagonist that blocks corticotropin-releasing factor receptors
id: CHEBI:76977
has_related_synonym: CRF antagonist
has_related_synonym: CRF antagonists
has_obo_namespace: chebi_ontology
has_related_synonym: corticotropin-releasing factor receptor antagonists
in_subset: 3 STAR
imported from: chebi.owl

xenoestrogen
type: Class
subclass of: endocrine disruptor
subclass of: estrogen
definition: A synthetic or semi-synthetic compound that has oestrogenic activity.
id: CHEBI:76988
database_cross_reference: Wikipedia:Xenoestrogen
has_obo_namespace: chebi_ontology
has_related_synonym: xenoestrogens
in_subset: 3 STAR
imported from: chebi.owl

phytoestrogen
type: Class
subclass of: estrogen
definition: Any compound produced by a plant that happens to have estrogenic activity.
id: CHEBI:76989
database_cross_reference: Wikipedia:Phytoestrogen
has_obo_namespace: chebi_ontology
has_related_synonym: phytoestrogens
in_subset: 3 STAR
imported from: chebi.owl

mycoestrogen
type: Class
subclass of: estrogen
definition: Any compound produced by a fungus that happens to have estrogenic activity.
id: CHEBI:76990
database_cross_reference: PMID:17291736
database_cross_reference: PMID:21392782
database_cross_reference: Wikipedia:Mycoestrogen
has_obo_namespace: chebi_ontology
has_related_synonym: mycoestrogens
in_subset: 3 STAR
imported from: chebi.owl

aryl hydrocarbon receptor antagonist
type: Class
subclass of: antagonist
has_related_synonym: AhR antagonist
has_related_synonym: AhR antagonists
has_related_synonym: AhR receptor antagonist
has_related_synonym: AhR receptor antagonists
definition: An antagonist that binds to and activates aryl hydrocarbon receptors (AhRs).
id: CHEBI:76998
has_related_synonym: aryl hydrocarbon receptor antagonists
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 1.10.99.* (oxidoreductases acting on diphenols and related substances as donors, other acceptors) inhibitor
type: Class
subclass of: EC 1.10.* (oxidoreductase acting on diphenols and related substances as donors) inhibitor
definition: An EC 1.10.* (oxidoreductase acting on diphenols and related substances as donors) inhibitor that interferes with the action of any such enzyme in the EC 1.10.99.* category.
id: CHEBI:77019
has_related_synonym: EC 1.10.99.* (oxidoreductases acting on diphenols and related substances as donors, other acceptors) inhibitors
has_related_synonym: EC 1.10.99.* inhibitor
has_related_synonym: EC 1.10.99.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: oxidoreductases acting on diphenols and related substances as donors, other acceptors (EC 1.10.99.*) inhibitor
has_related_synonym: oxidoreductases acting on diphenols and related substances as donors, other acceptors (EC 1.10.99.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor
type: Class
subclass of: EC 1.10.99.* (oxidoreductases acting on diphenols and related substances as donors, other acceptors) inhibitor
has_related_synonym: 1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide:quinone oxidoreductase inhibitor
has_related_synonym: 1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide:quinone oxidoreductase inhibitors
definition: An EC 1.10.99.* (oxidoreductases acting on diphenols and related substances as donors, other acceptors) inhibitor that interferes with the action of ribosyldihydronicotinamide dehydrogenase (quinone), EC 1.10.99.2.
id: CHEBI:77020
has_related_synonym: EC 1.10.99.2 (ribosyldihydronicotinamide dehydrogenase (quinone)) inhibitor
has_related_synonym: EC 1.10.99.2 (ribosyldihydronicotinamide dehydrogenase (quinone)) inhibitors
has_related_synonym: EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitors
has_related_synonym: EC 1.10.99.2 inhibitor
has_related_synonym: EC 1.10.99.2 inhibitors
has_related_synonym: N-ribosyldihydronicotinamide dehydrogenase (quinone) inhibitor
has_related_synonym: N-ribosyldihydronicotinamide dehydrogenase (quinone) inhibitors
has_related_synonym: NAD(P)H:quinone oxidoreductase-2 inhibitor
has_related_synonym: NAD(P)H:quinone oxidoreductase-2 inhibitors
has_related_synonym: NAD(P)H:quinone oxidoreductase2 inhibitor
has_related_synonym: NAD(P)H:quinone oxidoreductase2 inhibitors
has_related_synonym: NQO2 inhibitor
has_related_synonym: NQO2 inhibitors
has_related_synonym: NRH:quinone oxidoreductase 2 inhibitor
has_related_synonym: NRH:quinone oxidoreductase 2 inhibitors
has_related_synonym: QR2 inhibitor
has_related_synonym: QR2 inhibitors
database_cross_reference: Wikipedia:Ribosyldihydronicotinamide_dehydrogenase_(quinone)
has_obo_namespace: chebi_ontology
has_related_synonym: quinone reductase 2 inhibitor
has_related_synonym: quinone reductase 2 inhibitors
has_related_synonym: ribosyldihydronicotinamide dehydrogenase (quinone) (EC 1.10.99.2) inhibitor
has_related_synonym: ribosyldihydronicotinamide dehydrogenase (quinone) (EC 1.10.99.2) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.3.3.* (acyltransferase converting acyl to alkyl group on transfer) inhibitor
type: Class
subclass of: EC 2.3.* (acyltransferase) inhibitor
definition: An EC 2.3.* (acyltransferase) inhibitor that interferes with the action of an acyltransferase which converts the acyl group to an alkyl group on transfer (EC 2.3.3.*).
id: CHEBI:77022
has_related_synonym: EC 2.3.3.* (acyltransferase converting acyl to alkyl group on transfer) inhibitors
has_related_synonym: EC 2.3.3.* inhibitor
has_related_synonym: EC 2.3.3.* inhibitors
has_related_synonym: acyltransferase converting acyl to alkyl group on transfer (EC 2.3.3.*) inhibitor
has_related_synonym: acyltransferase converting acyl to alkyl group on transfer (EC 2.3.3.*) inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 2.3.3.1 [citrate (Si)-synthase] inhibitor
type: Class
subclass of: EC 2.3.3.* (acyltransferase converting acyl to alkyl group on transfer) inhibitor
has_related_synonym: (R)-citrate synthase inhibitor
has_related_synonym: (R)-citrate synthase inhibitors
definition: An EC 2.3.3.* (acyltransferase converting acyl to alkyl group on transfer) inhibitor that interferes with the action of citrate (Si)-synthase, EC 2.3.3.1.
id: CHEBI:77023
has_related_synonym: EC 2.3.3.1 (citrate (Si)-synthase) inhibitor
has_related_synonym: EC 2.3.3.1 (citrate (Si)-synthase) inhibitors
has_related_synonym: EC 2.3.3.1 [citrate (Si)-synthase] inhibitors
has_related_synonym: EC 2.3.3.1 inhibitor
has_related_synonym: EC 2.3.3.1 inhibitors
database_cross_reference: Wikipedia:Citrate_synthase
has_related_synonym: acetyl-CoA:oxaloacetate C-acetyltransferase [thioester-hydrolysing, (pro-S)-carboxymethyl forming] inhibitor
has_related_synonym: acetyl-CoA:oxaloacetate C-acetyltransferase [thioester-hydrolysing, (pro-S)-carboxymethyl forming] inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: citrate (Si)-synthase (EC 2.3.3.1) inhibitor
has_related_synonym: citrate (Si)-synthase (EC 2.3.3.1) inhibitors
has_related_synonym: citrate condensing enzyme inhibitor
has_related_synonym: citrate condensing enzyme inhibitors
has_related_synonym: citrate oxaloacetate-lyase [(pro-3S)-CH2COO->acetyl-CoA] inhibitor
has_related_synonym: citrate oxaloacetate-lyase [(pro-3S)-CH2COO->acetyl-CoA] inhibitors
has_related_synonym: citrate oxaloacetate-lyase, CoA-acetylating inhibitor
has_related_synonym: citrate oxaloacetate-lyase, CoA-acetylating inhibitors
has_related_synonym: citrate synthase inhibitor
has_related_synonym: citrate synthase inhibitors
has_related_synonym: citrate synthetase inhibitor
has_related_synonym: citrate synthetase inhibitors
has_related_synonym: citric synthase inhibitor
has_related_synonym: citric synthase inhibitors
has_related_synonym: citric-condensing enzyme inhibitor
has_related_synonym: citric-condensing enzyme inhibitors
has_related_synonym: citrogenase inhibitor
has_related_synonym: citrogenase inhibitors
has_related_synonym: condensing enzyme inhibitor
has_related_synonym: condensing enzyme inhibitors
has_related_synonym: oxalacetic transacetase inhibitor
has_related_synonym: oxalacetic transacetase inhibitors
has_related_synonym: oxaloacetate transacetase inhibitor
has_related_synonym: oxaloacetate transacetase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor
type: Class
subclass of: EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor
has_related_synonym: 4-nitrophenylphosphatase (EC 3.1.3.41) inhibitor
has_related_synonym: 4-nitrophenylphosphatase (EC 3.1.3.41) inhibitors
has_related_synonym: 4-nitrophenylphosphate phosphohydrolase inhibitor
has_related_synonym: 4-nitrophenylphosphate phosphohydrolase inhibitors
definition: An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of 4-nitrophenylphosphatase (EC 3.1.3.41).
id: CHEBI:77024
has_related_synonym: EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitors
has_related_synonym: EC 3.1.3.41 inhibitor
has_related_synonym: EC 3.1.3.41 inhibitors
has_related_synonym: Ecto-p-nitrophenyl phosphatase inhibitor
has_related_synonym: Ecto-p-nitrophenyl phosphatase inhibitors
has_related_synonym: K-pNPPase inhibitor
has_related_synonym: K-pNPPase inhibitors
has_related_synonym: NPPase inhibitor
has_related_synonym: NPPase inhibitors
has_related_synonym: PNPPase inhibitor
has_related_synonym: PNPPase inhibitors
database_cross_reference: Wikipedia:4-nitrophenylphosphatase
has_obo_namespace: chebi_ontology
has_related_synonym: nitrophenyl phosphatase inhibitor
has_related_synonym: nitrophenyl phosphatase inhibitors
has_related_synonym: p-nitrophenylphosphatase inhibitor
has_related_synonym: p-nitrophenylphosphatase inhibitors
has_related_synonym: p-nitrophenylphosphate phosphohydrolase inhibitor
has_related_synonym: p-nitrophenylphosphate phosphohydrolase inhibitors
has_related_synonym: para-nitrophenyl phosphatase inhibitor
has_related_synonym: para-nitrophenyl phosphatase inhibitors
has_related_synonym: xK-pNPPase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

mucolytic
type: Class
subclass of: drug
definition: A compound that alters the structure of mucus so as to decrease its viscosity and thereby facilitate its removal by ciliary action and expectoration. Compare with antitussives, which suppress the cough reflex, and expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing.
id: CHEBI:77034
database_cross_reference: PMID:17419975
database_cross_reference: PMID:17594730
database_cross_reference: PMID:20031934
database_cross_reference: PMID:2117172
database_cross_reference: PMID:22895919
has_obo_namespace: chebi_ontology
has_related_synonym: mucolytics
in_subset: 3 STAR
imported from: chebi.owl

expectorant
type: Class
subclass of: drug
id: CHEBI:77035
definition: Compounds that are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing. Compare with mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration, and antitussives, which suppress the cough reflex.
database_cross_reference: PMID:17594730
has_obo_namespace: chebi_ontology
has_related_synonym: expectorants
in_subset: 3 STAR
imported from: chebi.owl

EC 1.4.7.* (oxidoreductase acting on donor CH-NH2 group, Fe-S protein as acceptor) inhibitor
type: Class
subclass of: EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor
definition: An EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor that interferes with the action of any such enzyme using a iron-sulfur protein as acceptor (EC 1.4.7.*).
id: CHEBI:77088
has_related_synonym: EC 1.4.7.* (oxidoreductase acting on donor CH-NH2 group, Fe-S protein as acceptor) inhibitors
has_related_synonym: EC 1.4.7.* inhibitor
has_related_synonym: EC 1.4.7.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of oxidoreductase acting on donor CH-NH2 group, Fe-S protein as acceptor
has_related_synonym: inhibitors of oxidoreductase acting on donor CH-NH2 group, Fe-S protein as acceptor
has_related_synonym: oxidoreductase acting on donor CH-NH2 group, Fe-S protein as acceptor (EC 1.4.7.*) inhibitor
has_related_synonym: oxidoreductase acting on donor CH-NH2 group, Fe-S protein as acceptor (EC 1.4.7.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.5.1.49 (O-acetylhomoserine aminocarboxypropyltransferase) inhibitor
type: Class
subclass of: EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor
definition: An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of O-acetylhomoserine aminocarboxypropyltransferase (EC 2.5.1.49).
id: CHEBI:77089
has_related_synonym: EC 2.5.1.49 (O-acetylhomoserine aminocarboxypropyltransferase) inhibitors
has_related_synonym: EC 2.5.1.49 inhibitor
has_related_synonym: EC 2.5.1.49 inhibitors
has_related_synonym: O-acetyl-L-homoserine acetate-lyase (adding methanethiol) inhibitor
has_related_synonym: O-acetyl-L-homoserine acetate-lyase (adding methanethiol) inhibitors
has_related_synonym: O-acetyl-L-homoserine sulfhydrolase inhibitor
has_related_synonym: O-acetyl-L-homoserine sulfhydrolase inhibitors
has_related_synonym: O-acetyl-L-homoserine:methanethiol 3-amino-3-carboxypropyltransferase inhibitor
has_related_synonym: O-acetyl-L-homoserine:methanethiol 3-amino-3-carboxypropyltransferase inhibitors
has_related_synonym: O-acetylhomoserine (thiol)-lyase inhibitor
has_related_synonym: O-acetylhomoserine (thiol)-lyase inhibitors
has_related_synonym: O-acetylhomoserine aminocarboxypropyltransferase (EC 2.5.1.49) inhibitor
has_related_synonym: O-acetylhomoserine aminocarboxypropyltransferase (EC 2.5.1.49) inhibitors
has_related_synonym: O-acetylhomoserine aminocarboxypropyltransferase inhibitor
has_related_synonym: O-acetylhomoserine aminocarboxypropyltransferase inhibitors
has_related_synonym: O-acetylhomoserine sulfhydrolase inhibitor
has_related_synonym: O-acetylhomoserine sulfhydrolase inhibitors
database_cross_reference: Wikipedia:O-acetylhomoserine_aminocarboxypropyltransferase
has_obo_namespace: chebi_ontology
has_related_synonym: methionine synthase inhibitor
has_related_synonym: methionine synthase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor
type: Class
subclass of: EC 4.3.1.* (ammonia-lyase) inhibitor
has_related_synonym: (L-SOS)lyase inhibitor
has_related_synonym: (L-SOS)lyase inhibitors
definition: An EC 4.3.1.* (ammonia-lyase) inhibitor that interferes with the action of serine-sulfate ammonia-lyase (EC 4.3.1.10).
id: CHEBI:77090
has_related_synonym: EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitors
has_related_synonym: EC 4.3.1.10 inhibitor
has_related_synonym: EC 4.3.1.10 inhibitors
has_related_synonym: L-serine-O-sulfate ammonia-lyase (pyruvate-forming) inhibitor
has_related_synonym: L-serine-O-sulfate ammonia-lyase (pyruvate-forming) inhibitors
database_cross_reference: Wikipedia:Serine-sulfate_ammonia-lyase
has_obo_namespace: chebi_ontology
has_related_synonym: serine-sulfate ammonia-lyase (EC 4.3.1.10) inhibitor
has_related_synonym: serine-sulfate ammonia-lyase (EC 4.3.1.10) inhibitors
has_related_synonym: serine-sulfate ammonia-lyase inhibitor
has_related_synonym: serine-sulfate ammonia-lyase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.3.5.* (oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor) inhibitor
type: Class
subclass of: EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor
definition: An EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor that interferes with the action of any such enzyme using a quinone or related compound as acceptor (EC 1.3.5.*).
id: CHEBI:77102
has_related_synonym: EC 1.3.5.* (oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor) inhibitors
has_related_synonym: EC 1.3.5.* inhibitor
has_related_synonym: EC 1.3.5.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor
has_related_synonym: inhibitor of oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor (EC 1.3.5.*)
has_related_synonym: inhibitors of oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor
has_related_synonym: inhibitors of oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor (EC 1.3.5.*)
has_related_synonym: oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor (EC 1.3.5.*) inhibitor
has_related_synonym: oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor (EC 1.3.5.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.3.5.2 [dihydroorotate dehydrogenase (quinone)] inhibitor
type: Class
subclass of: EC 1.3.5.* (oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor) inhibitor
has_related_synonym: (S)-dihydroorotate:(acceptor) oxidoreductase inhibitor
has_related_synonym: (S)-dihydroorotate:(acceptor) oxidoreductase inhibitors
has_related_synonym: (S)-dihydroorotate:acceptor oxidoreductase inhibitor
has_related_synonym: (S)-dihydroorotate:acceptor oxidoreductase inhibitors
has_related_synonym: (S)-dihydroorotate:quinone oxidoreductase inhibitor
has_related_synonym: (S)-dihydroorotate:quinone oxidoreductase inhibitors
definition: An EC 1.3.5.* (oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor) inhibitor that interferes with the action of dihydroorotate dehydrogenase (quinone), EC 1.3.5.2.
id: CHEBI:77103
has_related_synonym: DHOD inhibitor
has_related_synonym: DHOD inhibitors
has_related_synonym: DHODH inhibitor
has_related_synonym: DHODH inhibitors
has_related_synonym: DHOdehase inhibitor
has_related_synonym: DHOdehase inhibitors
has_related_synonym: EC 1.3.5.2 (dihydroorotate dehydrogenase (quinone)) inhibitor
has_related_synonym: EC 1.3.5.2 (dihydroorotate dehydrogenase (quinone)) inhibitors
has_related_synonym: EC 1.3.5.2 [dihydroorotate dehydrogenase (quinone)] inhibitors
has_related_synonym: EC 1.3.5.2 inhibitor
has_related_synonym: EC 1.3.5.2 inhibitors
database_cross_reference: Wikipedia:Dihydroorotate_dehydrogenase_(quinone)
has_obo_namespace: chebi_ontology
has_related_synonym: dihydroorotate:ubiquinone oxidoreductase inhibitor
has_related_synonym: dihydroorotate:ubiquinone oxidoreductase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.10.2.* (oxidoreductase acting on diphenols and related substances as donors with a cytochrome as acceptor) inhibitor
type: Class
subclass of: EC 1.10.* (oxidoreductase acting on diphenols and related substances as donors) inhibitor
definition: An EC 1.10.* (oxidoreductase acting on diphenols and related substances as donors) inhibitor that interferes with the action of any such enzyme using a cytochrome as acceptor (EC 1.10.2.*).
id: CHEBI:77105
has_related_synonym: EC 1.10.2.* (oxidoreductase acting on diphenols and related substances as donors with a cytochrome as acceptor) inhibitors
has_related_synonym: EC 1.10.2.* inhibitor
has_related_synonym: EC 1.10.2.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of an oxidoreductase acting on diphenols and related substances as donors with a cytochrome as acceptor (EC 1.10.2.*)
has_related_synonym: inhibitors of an oxidoreductase acting on diphenols and related substances as donors with a cytochrome as acceptor (EC 1.10.2.*)
has_related_synonym: oxidoreductase acting on diphenols and related substances as donors with a cytochrome as acceptor (EC 1.10.2.*) inhibitor
has_related_synonym: oxidoreductase acting on diphenols and related substances as donors with a cytochrome as acceptor (EC 1.10.2.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.10.2.2 (quinol--cytochrome-c reductase) inhibitor
type: Class
subclass of: EC 1.10.2.* (oxidoreductase acting on diphenols and related substances as donors with a cytochrome as acceptor) inhibitor
definition: An EC 1.10.2.* (oxidoreductase acting on diphenols and related substances as donors with a cytochrome as acceptor) inhibitor that interferes with the action of quinol--cytochrome-c reductase (EC 1.10.2.2).
id: CHEBI:77106
has_related_synonym: EC 1.10.2.2 (quinol--cytochrome-c reductase) inhibitors
has_related_synonym: EC 1.10.2.2 inhibitor
has_related_synonym: EC 1.10.2.2 inhibitors
database_cross_reference: Wikipedia:Coenzyme_Q_-_cytochrome_c_reductase
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of quinol--cytochrome-c reductase (EC 1.10.2.2)
has_related_synonym: inhibitors of quinol--cytochrome-c reductase (EC 1.10.2.2)
has_related_synonym: quinol--cytochrome-c reductase (EC 1.10.2.2) inhibitor
has_related_synonym: quinol--cytochrome-c reductase (EC 1.10.2.2) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.1.1.141 [15-hydroxyprostaglandin dehydrogenase (NAD(+))] inhibitor
type: Class
subclass of: EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor
has_related_synonym: (5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-13-enoate:NAD(+) 15-oxidoreductase inhibitor
has_related_synonym: (5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-13-enoate:NAD(+) 15-oxidoreductase inhibitors
has_related_synonym: (5Z,13E,15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate:NAD(+) 15-oxidoreductase inhibitor
has_related_synonym: (5Z,13E,15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate:NAD(+) 15-oxidoreductase inhibitors
has_related_synonym: 11alpha,15-dihydroxy-9-oxoprost-13-enoate:NAD(+) 15-oxidoreductase inhibitor
has_related_synonym: 11alpha,15-dihydroxy-9-oxoprost-13-enoate:NAD(+) 15-oxidoreductase inhibitors
has_related_synonym: 15-OH-PGDH inhibitor
has_related_synonym: 15-OH-PGDH inhibitors
has_related_synonym: 15-hydroxyprostaglandin dehydrogenase (NAD(+)) (EC 1.1.1.141) inhibitor
has_related_synonym: 15-hydroxyprostaglandin dehydrogenase (NAD(+)) (EC 1.1.1.141) inhibitors
has_related_synonym: 15-hydroxyprostaglandin dehydrogenase (NAD(+)) inhibitor
has_related_synonym: 15-hydroxyprostaglandin dehydrogenase (NAD(+)) inhibitors
has_related_synonym: 15-hydroxyprostaglandin dehydrogenase inhibitor
has_related_synonym: 15-hydroxyprostaglandin dehydrogenase inhibitors
has_related_synonym: 15-hydroxyprostanoic dehydrogenase inhibitor
has_related_synonym: 15-hydroxyprostanoic dehydrogenase inhibitors
definition: An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of 15-hydroxyprostaglandin dehydrogenase (NAD(+)) (EC 1.1.1.141).
id: CHEBI:77108
has_related_synonym: EC 1.1.1.141 [15-hydroxyprostaglandin dehydrogenase (NAD(+))] inhibitors
has_related_synonym: EC 1.1.1.141 inhibitor
has_related_synonym: EC 1.1.1.141 inhibitors
has_related_synonym: NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase (type I) inhibitor
has_related_synonym: NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase (type I) inhibitors
has_related_synonym: NAD-specific 15-hydroxyprostaglandin dehydrogenase inhibitor
has_related_synonym: NAD-specific 15-hydroxyprostaglandin dehydrogenase inhibitors
has_related_synonym: PGDH inhibitor
has_related_synonym: PGDH inhibitors
database_cross_reference: PMID:21072165
database_cross_reference: Wikipedia:15-hydroxyprostaglandin_dehydrogenase_(NAD%2B)
has_obo_namespace: chebi_ontology
has_related_synonym: prostaglandin dehydrogenase inhibitor
has_related_synonym: prostaglandin dehydrogenase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.21.3.* (oxidoreductase acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor) inhibitor
type: Class
subclass of: EC 1.21.* (oxidoreductase acting on X-H and Y-H to form an X-Y bond) inhibitor
definition: An EC 1.21.* (oxidoreductase acting on X-H and Y-H to form an X-Y bond) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.21.3.*).
id: CHEBI:77109
has_related_synonym: EC 1.21.3.* (oxidoreductase acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor) inhibitors
has_related_synonym: EC 1.21.3.* inhibitor
has_related_synonym: EC 1.21.3.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of oxidoreductase acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor
has_related_synonym: inhibitor of oxidoreductase acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor (EC 1.21.3.*)
has_related_synonym: inhibitors of oxidoreductase acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor
has_related_synonym: inhibitors of oxidoreductase acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor (EC 1.21.3.*)
has_related_synonym: oxidoreductase acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor (EC 1.21.3.*) inhibitor
has_related_synonym: oxidoreductase acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor (EC 1.21.3.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.21.3.3 (reticuline oxidase) inhibitor
type: Class
subclass of: EC 1.21.3.* (oxidoreductase acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor) inhibitor
has_related_synonym: (S)-reticuline:oxygen oxidoreductase (methylene-bridge-forming) inhibitor
has_related_synonym: (S)-reticuline:oxygen oxidoreductase (methylene-bridge-forming) inhibitors
definition: An EC 1.21.3.* (oxidoreductase acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor) inhibitor that interferes with the action of reticuline oxidase (EC 1.21.3.3, previously EC 1.5.3.9).
has_related_synonym: BBE inhibitor
has_related_synonym: BBE inhibitors
id: CHEBI:77110
has_related_synonym: EC 1.21.3.3 (reticuline oxidase) inhibitors
has_related_synonym: EC 1.21.3.3 inhibitor
has_related_synonym: EC 1.21.3.3 inhibitors
has_related_synonym: EC 1.5.3.9 inhibitor
has_related_synonym: EC 1.5.3.9 inhibitors
database_cross_reference: Wikipedia:Reticuline_oxidase
has_related_synonym: berberine bridge enzyme inhibitor
has_related_synonym: berberine bridge enzyme inhibitors
has_related_synonym: berberine-bridge-forming enzyme inhibitor
has_related_synonym: berberine-bridge-forming enzyme inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: reticuline oxidase (EC 1.21.3.3) inhibitor
has_related_synonym: reticuline oxidase (EC 1.21.3.3) inhibitors
has_related_synonym: reticuline oxidase inhibitor
has_related_synonym: reticuline oxidase inhibitors
has_related_synonym: tetrahydroprotoberberine synthase inhibitor
has_related_synonym: tetrahydroprotoberberine synthase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.1.1.116 [3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase] inhibitor
type: Class
subclass of: EC 2.1.1.* (methyltransferases) inhibitor
has_related_synonym: 3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase (EC 2.1.1.116) inhibitor
has_related_synonym: 3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase (EC 2.1.1.116) inhibitors
definition: An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of 3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase (EC 2.1.1.116).
id: CHEBI:77111
has_related_synonym: EC 2.1.1.116 [3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase] inhibitors
has_related_synonym: EC 2.1.1.116 inhibitor
has_related_synonym: EC 2.1.1.116 inhibitors
has_related_synonym: S-adenosyl-L-methionine:3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase inhibitor
has_related_synonym: S-adenosyl-L-methionine:3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase inhibitors
database_cross_reference: Wikipedia:3'-hydroxy-N-methyl-(S)-coclaurine_4'-O-methyltransferase
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.11.10 (IkappaB kinase) inhibitor
type: Class
subclass of: EC 2.7.11.* (protein-serine/threonine kinase) inhibitor
has_related_synonym: ATP:[IkappaB protein] phosphotransferase
has_related_synonym: ATP:[IkappaB protein] phosphotransferase inhibitor
definition: An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of IkappaB kinase (EC 2.7.11.10).
id: CHEBI:77113
has_related_synonym: CHUK inhibitor
has_related_synonym: CHUK inhibitors
has_related_synonym: EC 2.7.11.10 (IkappaB kinase) inhibitors
has_related_synonym: EC 2.7.11.10 inhibitor
has_related_synonym: EC 2.7.11.10 inhibitors
has_related_synonym: IKBKA inhibitor
has_related_synonym: IKBKA inhibitors
has_related_synonym: IKBKB inhibitor
has_related_synonym: IKBKB inhibitors
has_related_synonym: IKK inhibitor
has_related_synonym: IKK inhibitors
has_related_synonym: IKK-1 inhibitor
has_related_synonym: IKK-1 inhibitors
has_related_synonym: IKK-2 inhibitor
has_related_synonym: IKK-2 inhibitors
has_related_synonym: IkappaB kinase (EC 2.7.11.10) inhibitor
has_related_synonym: IkappaB kinase (EC 2.7.11.10) inhibitors
has_related_synonym: IkappaB kinase inhibitor
has_related_synonym: IkappaB kinase inhibitors
has_related_synonym: STK12 inhibitor
has_related_synonym: STK12 inhibitors
has_related_synonym: TANK-binding kinase 1 inhibitor
has_related_synonym: TANK-binding kinase 1 inhibitors
has_related_synonym: TBK1 inhibitor
has_related_synonym: TBK1 inhibitors
database_cross_reference: Wikipedia:IkappaB_kinase
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor
type: Class
subclass of: EC 2.1.1.* (methyltransferases) inhibitor
has_related_synonym: (S)-tetrahydroprotoberberine N-methyltransferase (EC 2.1.1.122) inhibitor
has_related_synonym: (S)-tetrahydroprotoberberine N-methyltransferase (EC 2.1.1.122) inhibitors
has_related_synonym: (S)-tetrahydroprotoberberine N-methyltransferase inhibitor
has_related_synonym: (S)-tetrahydroprotoberberine N-methyltransferase inhibitors
definition: An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of (S)-tetrahydroprotoberberine N-methyltransferase (EC 2.1.1.122).
id: CHEBI:77115
has_related_synonym: EC 2.1.1.122 ((S)-tetrahydroprotoberberine N-methyltransferase) inhibitor
has_related_synonym: EC 2.1.1.122 ((S)-tetrahydroprotoberberine N-methyltransferase) inhibitors
has_related_synonym: EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitors
has_related_synonym: EC 2.1.1.122 inhibitor
has_related_synonym: EC 2.1.1.122 inhibitors
has_related_synonym: S-adenosyl-L-methionine:(S)-7,8,13,14-tetrahydroprotoberberine cis-N-methyltransferase inhibitor
has_related_synonym: S-adenosyl-L-methionine:(S)-7,8,13,14-tetrahydroprotoberberine cis-N-methyltransferase inhibitors
database_cross_reference: Wikipedia:(S)-tetrahydroprotoberberine_N-methyltransferase
has_obo_namespace: chebi_ontology
has_related_synonym: tetrahydroprotoberberine cis-N-methyltransferase inhibitor
has_related_synonym: tetrahydroprotoberberine cis-N-methyltransferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.5.5.* (hydrolase acting on C-N bonds in nitriles) inhibitor
type: Class
subclass of: EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor
definition: An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any such enzyme acting on the C-N bond of nitriles (EC 3.5.5.*).
id: CHEBI:77117
has_related_synonym: EC 3.5.5.* (hydrolase acting on C-N bonds in nitriles) inhibitors
has_related_synonym: EC 3.5.5.* inhibitor
has_related_synonym: EC 3.5.5.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: hydrolase acting on C-N bonds in nitriles (EC 3.5.5.*) inhibitor
has_related_synonym: hydrolase acting on C-N bonds in nitriles (EC 3.5.5.*) inhibitors
has_related_synonym: inhibitor of hydrolases acting on C-N bonds in nitriles
has_related_synonym: inhibitors of hydrolases acting on C-N bonds in nitriles
in_subset: 3 STAR
imported from: chebi.owl

EC 3.5.5.1 (nitrilase) inhibitor
type: Class
subclass of: EC 3.5.5.* (hydrolase acting on C-N bonds in nitriles) inhibitor
definition: An EC 3.5.5.* (hydrolase acting on C-N bonds in nitriles) inhibitor that interferes with the action of nitrilase (EC 3.5.5.1).
id: CHEBI:77118
has_related_synonym: EC 3.5.5.1 (nitrilase) inhibitors
has_related_synonym: EC 3.5.5.1 inhibitor
has_related_synonym: EC 3.5.5.1 inhibitors
database_cross_reference: Wikipedia:Nitrilase
has_related_synonym: acetonitrilase inhibitor
has_related_synonym: acetonitrilase inhibitors
has_related_synonym: benzonitrilase inhibitor
has_related_synonym: benzonitrilase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: nitrilase (EC 3.5.5.1) inhibitor
has_related_synonym: nitrilase (EC 3.5.5.1) inhibitors
has_related_synonym: nitrile aminohydrolase inhibitor
has_related_synonym: nitrile aminohydrolase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.1.1.189 (prostaglandin-E2 9-reductase) inhibitor
type: Class
subclass of: EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor
has_related_synonym: (5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP(+) 9-oxidoreductase inhibitor
has_related_synonym: (5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP(+) 9-oxidoreductase inhibitors
has_related_synonym: 9-keto-prostaglandin E2 reductase inhibitor
has_related_synonym: 9-keto-prostaglandin E2 reductase inhibitors
has_related_synonym: 9-ketoprostaglandin reductase inhibitor
has_related_synonym: 9-ketoprostaglandin reductase inhibitors
definition: An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of prostaglandin-E2 9-reductase (EC 1.1.1.189).
id: CHEBI:77119
has_related_synonym: EC 1.1.1.189 (prostaglandin-E2 9-reductase) inhibitors
has_related_synonym: EC 1.1.1.189 inhibitor
has_related_synonym: EC 1.1.1.189 inhibitors
has_related_synonym: PGE-9-ketoreductase inhibitor
has_related_synonym: PGE-9-ketoreductase inhibitors
has_related_synonym: PGE2 9-oxoreductase inhibitor
has_related_synonym: PGE2 9-oxoreductase inhibitors
has_related_synonym: PGE2-9-OR inhibitor
has_related_synonym: PGE2-9-OR inhibitors
has_related_synonym: PGE2-9-ketoreductase inhibitor
has_related_synonym: PGE2-9-ketoreductase inhibitors
database_cross_reference: Wikipedia:Prostaglandin-E2_9-reductase
has_obo_namespace: chebi_ontology
has_related_synonym: prostaglandin 9-ketoreductase inhibitor
has_related_synonym: prostaglandin 9-ketoreductase inhibitors
has_related_synonym: prostaglandin E 9-ketoreductase inhibitor
has_related_synonym: prostaglandin E 9-ketoreductase inhibitors
has_related_synonym: prostaglandin E2-9-oxoreductase inhibitor
has_related_synonym: prostaglandin E2-9-oxoreductase inhibitors
has_related_synonym: prostaglandin-E2 9-reductase (EC 1.1.1.189) inhibitor
has_related_synonym: prostaglandin-E2 9-reductase (EC 1.1.1.189) inhibitors
has_related_synonym: reductase, 15-hydroxy-9-oxoprostaglandin inhibitor
has_related_synonym: reductase, 15-hydroxy-9-oxoprostaglandin inhibitors
in_subset: 3 STAR
imported from: chebi.owl

Toll-like receptor 2 agonist
type: Class
subclass of: agonist
definition: An agonist that selectively binds to and activates the Toll-like receptor 2 (TLR 2, TLR-2) protein.
id: CHEBI:77161
database_cross_reference: PMID:24434326
has_related_synonym: TLR 2 agonist
has_related_synonym: TLR 2 agonists
has_related_synonym: TLR-2 agonist
has_related_synonym: TLR-2 agonists
has_related_synonym: Toll-like receptor 2 agonists
has_related_synonym: Toll-like receptor-2 agonist
has_related_synonym: Toll-like receptor-2 agonists
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

histological dye
type: Class
subclass of: dye
definition: A dye used in microscopic or electron microscopic examination of cells and tissues to give contrast and to highlight particular features of interest, such as nuclei and cytoplasm.
id: CHEBI:77178
database_cross_reference: PMID:21756020
database_cross_reference: PMID:21838612
database_cross_reference: PMID:23901948
has_related_synonym: biological stain
has_related_synonym: biological stains
has_obo_namespace: chebi_ontology
has_related_synonym: histological dyes
has_related_synonym: histological stain
has_related_synonym: histological stains
in_subset: 3 STAR
imported from: chebi.owl

food colouring
type: Class
subclass of: food additive
definition: A food additive that imparts colour to food. In European countries, E-numbers for permitted food colours are from E 100 to E 199, divided into yellows (E 100-109), oranges (E 110-119), reds (E 120-129), blues and violets (E 130-139), greens (E 140-149), browns and blacks (E 150-159), and others (E 160-199).
id: CHEBI:77182
database_cross_reference: Wikipedia:Food_coloring
has_obo_namespace: chebi_ontology
has_related_synonym: food coloring
has_related_synonym: food colorings
has_related_synonym: food colourings
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.1.33 (pantothenate kinase) inhibitor
type: Class
subclass of: EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor
has_related_synonym: ATP:(R)-pantothenate 4'-phosphotransferase inhibitor
has_related_synonym: ATP:(R)-pantothenate 4'-phosphotransferase inhibitors
has_related_synonym: ATP:pantothenate 4'-phosphotransferase inhibitor
has_related_synonym: ATP:pantothenate 4'-phosphotransferase inhibitors
definition: An EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor that interferes with the action of pantothenate kinase (EC 2.7.1.33).
id: CHEBI:77194
has_related_synonym: D-pantothenate kinase inhibitor
has_related_synonym: D-pantothenate kinase inhibitors
has_related_synonym: EC 2.7.1.33 (pantothenate kinase) inhibitors
has_related_synonym: EC 2.7.1.33 inhibitor
has_related_synonym: EC 2.7.1.33 inhibitors
database_cross_reference: Wikipedia:Pantothenate_kinase
has_obo_namespace: chebi_ontology
has_related_synonym: pantothenate kinase (EC 2.7.1.33) inhibitor
has_related_synonym: pantothenate kinase (EC 2.7.1.33) inhibitors
has_related_synonym: pantothenate kinase (phosphorylating) inhibitor
has_related_synonym: pantothenate kinase (phosphorylating) inhibitors
has_related_synonym: pantothenic acid kinase inhibitor
has_related_synonym: pantothenic acid kinase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor
type: Class
subclass of: EC 3.4.24.* (metalloendopeptidase) inhibitor
definition: An EC 3.4.24.* (metalloendopeptidase) inhibitor that interferes with the action of anthrax lethal factor endopeptidase (EC 3.4.24.83).
id: CHEBI:77255
has_related_synonym: EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitors
has_related_synonym: EC 3.4.24.83 inhibitor
has_related_synonym: EC 3.4.24.83 inhibitors
database_cross_reference: Wikipedia:Anthrax_lethal_factor_endopeptidase
has_related_synonym: anthrax lethal factor endopeptidase (EC 3.4.24.83) inhibitor
has_related_synonym: anthrax lethal factor endopeptidase (EC 3.4.24.83) inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: lethal toxin inhibitor
has_related_synonym: lethal toxin inhibitors
in_subset: 3 STAR
imported from: chebi.owl

cardioprotective agent
type: Class
subclass of: protective agent
definition: Any protective agent that is able to prevent damage to the heart.
id: CHEBI:77307
has_related_synonym: cardioprotective agents
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

pregnane X receptor agonist
type: Class
subclass of: agonist
definition: An agonist that selectively binds to and activates a pregnane X receptor.
id: CHEBI:77318
has_related_synonym: PXR agonist
has_related_synonym: PXR agonists
database_cross_reference: Wikipedia:Pregnane_X_receptor
has_obo_namespace: chebi_ontology
has_related_synonym: pregnane X receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

UDP-glucuronosyltransferase activator
type: Class
subclass of: enzyme activator
definition: Any compound that activates UDP-glucuronosyltransferase (EC 2.4.1.17).
id: CHEBI:77324
has_related_synonym: UDP-glucuronosyltransferase activators
database_cross_reference: Wikipedia:Glucuronosyltransferase
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

androstane receptor agonist
type: Class
subclass of: agonist
definition: An agonist that selectively binds to and activates androstane receptors.
has_related_synonym: CAR agonist
has_related_synonym: CAR agonists
id: CHEBI:77326
database_cross_reference: Wikipedia:Constitutive_androstane_receptor
has_related_synonym: androstane receptor agonists
has_obo_namespace: chebi_ontology
has_related_synonym: constitutive androstane receptor agonist
has_related_synonym: constitutive androstane receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor
type: Class
subclass of: EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD(+) or NADP(+) as acceptor) inhibitor
definition: An EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of trypanothione-disulfide reductase (EC 1.8.1.12).
id: CHEBI:77402
has_related_synonym: EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitors
has_related_synonym: EC 1.8.1.12 inhibitor
has_related_synonym: EC 1.8.1.12 inhibitors
has_related_synonym: N(1),N(8)-bis(glutathionyl)spermidine reductase inhibitor
has_related_synonym: N(1),N(8)-bis(glutathionyl)spermidine reductase inhibitors
has_related_synonym: NADPH2:trypanothione oxidoreductase inhibitor
has_related_synonym: NADPH2:trypanothione oxidoreductase inhibitors
has_related_synonym: NADPH:trypanothione oxidoreductase inhibitor
has_related_synonym: NADPH:trypanothione oxidoreductase inhibitors
database_cross_reference: Wikipedia:Trypanothione-disulfide_reductase
has_obo_namespace: chebi_ontology
has_related_synonym: trypanothione reductase inhibitor
has_related_synonym: trypanothione reductase inhibitors
has_related_synonym: trypanothione-disulfide reductase (EC 1.8.1.12) inhibitor
has_related_synonym: trypanothione-disulfide reductase (EC 1.8.1.12) inhibitors
has_related_synonym: trypanothione:NADP(+) oxidoreductase inhibitor
has_related_synonym: trypanothione:NADP(+) oxidoreductase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.1.1.188 (prostaglandin-F synthase) inhibitor
type: Class
subclass of: EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor
has_related_synonym: (5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP(+) 11-oxidoreductase inhibitor
has_related_synonym: (5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP(+) 11-oxidoreductase inhibitors
definition: An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of prostaglandin-F synthase (EC 1.1.1.188).
id: CHEBI:77425
has_related_synonym: EC 1.1.1.188 (prostaglandin-F synthase) inhibitors
has_related_synonym: EC 1.1.1.188 inhibitor
has_related_synonym: EC 1.1.1.188 inhibitors
has_related_synonym: NADPH-dependent prostaglandin D2 11-keto reductase inhibitor
has_related_synonym: NADPH-dependent prostaglandin D2 11-keto reductase inhibitors
has_related_synonym: PGD2 11-ketoreductase inhibitor
has_related_synonym: PGD2 11-ketoreductase inhibitors
has_related_synonym: PGF synthetase inhibitor
has_related_synonym: PGF synthetase inhibitors
has_related_synonym: PGF2alpha synthetase inhibitor
has_related_synonym: PGF2alpha synthetase inhibitors
database_cross_reference: Wikipedia:Prostaglandin-F_synthase
has_obo_namespace: chebi_ontology
has_related_synonym: prostaglandin 11-keto reductase inhibitor
has_related_synonym: prostaglandin 11-keto reductase inhibitors
has_related_synonym: prostaglandin 11-ketoreductase inhibitor
has_related_synonym: prostaglandin 11-ketoreductase inhibitors
has_related_synonym: prostaglandin D2-ketoreductase inhibitor
has_related_synonym: prostaglandin D2-ketoreductase inhibitors
has_related_synonym: prostaglandin F synthase inhibitor
has_related_synonym: prostaglandin F synthase inhibitors
has_related_synonym: prostaglandin F synthetase inhibitor
has_related_synonym: prostaglandin F synthetase inhibitors
has_related_synonym: prostaglandin-D2 11-reductase inhibitor
has_related_synonym: prostaglandin-D2 11-reductase inhibitors
has_related_synonym: reductase, 15-hydroxy-11-oxoprostaglandin inhibitor
has_related_synonym: reductase, 15-hydroxy-11-oxoprostaglandin inhibitors
has_related_synonym: synthetase, prostaglandin F2alpha inhibitor
has_related_synonym: synthetase, prostaglandin F2alpha inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.1.1.25 (shikimate dehydrogenase) inhibitor
type: Class
subclass of: EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor
has_related_synonym: 5-dehydroshikimate reductase inhibitor
has_related_synonym: 5-dehydroshikimate reductase inhibitors
has_related_synonym: 5-dehydroshikimic reductase inhibitor
has_related_synonym: 5-dehydroshikimic reductase inhibitors
definition: An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of shikimate dehydrogenase (EC 1.1.1.25).
has_related_synonym: AroE inhibitor
has_related_synonym: AroE inhibitors
id: CHEBI:77484
has_related_synonym: DHS reductase inhibitor
has_related_synonym: DHS reductase inhibitors
has_related_synonym: EC 1.1.1.25 (shikimate dehydrogenase) inhibitors
has_related_synonym: EC 1.1.1.25 inhibitor
has_related_synonym: EC 1.1.1.25 inhibitors
database_cross_reference: Wikipedia:Shikimate_dehydrogenase
has_obo_namespace: chebi_ontology
has_related_synonym: dehydroshikimic reductase inhibitor
has_related_synonym: dehydroshikimic reductase inhibitors
has_related_synonym: shikimate 5-dehydrogenase inhibitor
has_related_synonym: shikimate 5-dehydrogenase inhibitors
has_related_synonym: shikimate dehydrogenase (EC 1.1.1.25) inhibitor
has_related_synonym: shikimate dehydrogenase (EC 1.1.1.25) inhibitors
has_related_synonym: shikimate dehydrogenase inhibitor
has_related_synonym: shikimate dehydrogenase inhibitors
has_related_synonym: shikimate oxidoreductase inhibitor
has_related_synonym: shikimate oxidoreductase inhibitors
has_related_synonym: shikimate:NADP(+) 3-oxidoreductase inhibitor
has_related_synonym: shikimate:NADP(+) 3-oxidoreductase inhibitors
has_related_synonym: shikimate:NADP(+) 5-oxidoreductase inhibitor
has_related_synonym: shikimate:NADP(+) 5-oxidoreductase inhibitors
has_related_synonym: shikimate:NADP(+) oxidoreductase inhibitor
has_related_synonym: shikimate:NADP(+) oxidoreductase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

bradykinin receptor agonist
type: Class
subclass of: agonist
definition: An agonist that binds to and activates bradykinin receptors
id: CHEBI:77495
database_cross_reference: Wikipedia:Bradykinin_receptor
has_related_synonym: bradykinin receptor agonists
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

bradykinin receptor B2 agonist
type: Class
subclass of: bradykinin receptor agonist
definition: A bradykinin agonist that binds to and activates bradykinin B2 receptors.
has_related_synonym: B2 receptor agonist
has_related_synonym: B2 receptor agonists
has_related_synonym: B2R agonist
has_related_synonym: B2R agonists
id: CHEBI:77496
database_cross_reference: Wikipedia:Bradykinin_receptor_B2
has_related_synonym: bradykinin receptor B2 agonists
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

thermal degradation product
type: Class
subclass of: chemical role
definition: Any product obtained as a result of thermally induced non-enzymatic degradation.
id: CHEBI:77521
has_obo_namespace: chebi_ontology
has_related_synonym: thermal artefact
has_related_synonym: thermal artefacts
has_related_synonym: thermal degradation products
in_subset: 3 STAR
imported from: chebi.owl

Maillard reaction product
type: Class
subclass of: thermal degradation product
definition: Any thermal degradation product obtained as a result of a chemical reaction between an amino acid and a reducing sugar (Maillard reaction, a non-enzymatic browning procedure that usually imparts flavour to starch-based food products).
id: CHEBI:77523
has_related_synonym: Maillard product
has_related_synonym: Maillard products
database_cross_reference: PMID:23588491
database_cross_reference: PMID:23612540
database_cross_reference: PMID:24246231
database_cross_reference: Wikipedia:Maillard_reaction
has_obo_namespace: chebi_ontology
has_related_synonym: maillard reaction products
in_subset: 3 STAR
imported from: chebi.owl

eugeroic
type: Class
subclass of: psychotropic drug
definition: A phsychotropic drug that improves wakefulness and alertness, and reduces tiredness, drowsiness, and the need for sleep. Eugeroics are relatively non-addictive and are used in the treatment of narcolepsy and other sleep disorders.
id: CHEBI:77567
database_cross_reference: Wikipedia:Wakefulness-promoting_agent
has_obo_namespace: chebi_ontology
has_related_synonym: eugeroics
has_related_synonym: vigilance promoting agent
has_related_synonym: vigilance promoting agents
has_related_synonym: vigilance promoting drug
has_related_synonym: vigilance promoting drugs
has_related_synonym: vigilance-promoting agent
has_related_synonym: vigilance-promoting agents
has_related_synonym: vigilance-promoting drug
has_related_synonym: vigilance-promoting drugs
has_related_synonym: wake-promoting agent
has_related_synonym: wake-promoting agents
has_related_synonym: wake-promoting drug
has_related_synonym: wake-promoting drugs
has_related_synonym: wakefulness-promoting agent
has_related_synonym: wakefulness-promoting agents
has_related_synonym: wakefulness-promoting drug
has_related_synonym: wakefulness-promoting drugs
in_subset: 3 STAR
imported from: chebi.owl

loop diuretic
type: Class
subclass of: diuretic
definition: A diuretic that acts on the ascending loop of Henle in the kidney.
id: CHEBI:77608
database_cross_reference: Wikipedia:Loop_diuretic
has_obo_namespace: chebi_ontology
has_related_synonym: loop diuretics
in_subset: 3 STAR
imported from: chebi.owl

EC 1.1.1.267 (1-deoxy-D-xylulose-5-phosphate reductoisomerase) inhibitor
type: Class
subclass of: EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor
has_related_synonym: 1-deoxy-D-xylulose-5-phosphate isomeroreductase inhibitor
has_related_synonym: 1-deoxy-D-xylulose-5-phosphate isomeroreductase inhibitors
has_related_synonym: 1-deoxy-D-xylulose-5-phosphate reductoisomerase (EC 1.1.1.267) inhibitor
has_related_synonym: 1-deoxy-D-xylulose-5-phosphate reductoisomerase (EC 1.1.1.267) inhibitors
has_related_synonym: 1-deoxy-D-xylulose-5-phosphate reductoisomerase inhibitor
has_related_synonym: 1-deoxy-D-xylulose-5-phosphate reductoisomerase inhibitors
has_related_synonym: 1-deoxyxylulose-5-phosphate reductoisomerase inhibitor
has_related_synonym: 1-deoxyxylulose-5-phosphate reductoisomerase inhibitors
has_related_synonym: 2-C-methyl-D-erythritol-4-phosphate:NADP(+) oxidoreductase (isomerising) inhibitor
has_related_synonym: 2-C-methyl-D-erythritol-4-phosphate:NADP(+) oxidoreductase (isomerising) inhibitors
has_related_synonym: 2-C-methyl-D-erythritol-4-phosphate:NADP(+) oxidoreductase (isomerizing) inhibitor
has_related_synonym: 2-C-methyl-D-erythritol-4-phosphate:NADP(+) oxidoreductase (isomerizing) inhibitors
has_related_synonym: 2C-methyl-D-erythritol-4-phosphate (MEP) synthase inhibitor
has_related_synonym: 2C-methyl-D-erythritol-4-phosphate (MEP) synthase inhibitors
definition: An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of 1-deoxy-D-xylulose-5-phosphate reductoisomerase (EC 1.1.1.267).
id: CHEBI:77654
has_related_synonym: DXP-reductoisomerase inhibitor
has_related_synonym: DXP-reductoisomerase inhibitors
has_related_synonym: EC 1.1.1.267 (1-deoxy-D-xylulose-5-phosphate reductoisomerase) inhibitors
has_related_synonym: EC 1.1.1.267 inhibitor
has_related_synonym: EC 1.1.1.267 inhibitors
database_cross_reference: Wikipedia:DXP_reductoisomerase
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 4.3.1.3 (histidine ammonia-lyase) inhibitor
type: Class
subclass of: EC 4.3.1.* (ammonia-lyase) inhibitor
definition: An EC 4.3.1.* (ammonia-lyase) inhibitor that interferes with the action of histidine ammonia-lyase (EC 4.3.1.3).
id: CHEBI:77703
has_related_synonym: EC 4.3.1.3 (histidine ammonia-lyase) inhibitors
has_related_synonym: EC 4.3.1.3 inhibitor
has_related_synonym: EC 4.3.1.3 inhibitors
has_related_synonym: L-histidine ammonia-lyase (urocanate-forming) inhibitor
has_related_synonym: L-histidine ammonia-lyase (urocanate-forming) inhibitors
has_related_synonym: L-histidine ammonia-lyase inhibitor
has_related_synonym: L-histidine ammonia-lyase inhibitors
database_cross_reference: Wikipedia:Histidine_ammonia-lyase
has_obo_namespace: chebi_ontology
has_related_synonym: histidase inhibitor
has_related_synonym: histidase inhibitors
has_related_synonym: histidinase inhibitor
has_related_synonym: histidinase inhibitors
has_related_synonym: histidine alpha-deaminase inhibitor
has_related_synonym: histidine alpha-deaminase inhibitors
has_related_synonym: histidine ammonia-lyase (EC 4.3.1.3) inhibitor
has_related_synonym: histidine ammonia-lyase (EC 4.3.1.3) inhibitors
has_related_synonym: histidine ammonia-lyase inhibitor
has_related_synonym: histidine ammonia-lyase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.19.* (omega-peptidase) inhibitor
type: Class
subclass of: EC 3.4.* (hydrolases acting on peptide bond) inhibitor
definition: Any EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes with the action of any omega-peptidase (EC 3.4.19.*).
id: CHEBI:77705
has_related_synonym: EC 3.4.19.* (omega-peptidase) inhibitors
has_related_synonym: EC 3.4.19.* inhibitor
has_related_synonym: EC 3.4.19.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: omega-peptidase (EC 3.4.19.*) inhibitor
has_related_synonym: omega-peptidase (EC 3.4.19.*) inhibitors
has_related_synonym: omega-peptidase inhibitor
has_related_synonym: omega-peptidase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.19.3 (pyroglutamyl-peptidase I) inhibitor
type: Class
subclass of: EC 3.4.19.* (omega-peptidase) inhibitor
has_related_synonym: 5-oxoprolyl-peptidase inhibitors
definition: An EC 3.4.19.* (omega-peptidase) inhibitor that interferes with the action of pyroglutamyl-peptidase I (EC 3.4.19.3).
id: CHEBI:77706
has_related_synonym: EC 3.4.19.3 (pyroglutamyl-peptidase I) inhibitors
has_related_synonym: EC 3.4.19.3 inhibitor
has_related_synonym: EC 3.4.19.3 inhibitors
has_related_synonym: L-pyroglutamyl peptide hydrolase inhibitor
has_related_synonym: L-pyroglutamyl peptide hydrolase inhibitors
has_related_synonym: L-pyrrolidonecarboxylate peptidase inhibitor
has_related_synonym: L-pyrrolidonecarboxylate peptidase inhibitors
database_cross_reference: Wikipedia:Pyroglutamyl-peptidase_I
has_obo_namespace: chebi_ontology
has_related_synonym: pyrase inhibitor
has_related_synonym: pyrase inhibitors
has_related_synonym: pyroglutamate aminopeptidase inhibitor
has_related_synonym: pyroglutamate aminopeptidase inhibitors
has_related_synonym: pyroglutamidase inhibitor
has_related_synonym: pyroglutamidase inhibitors
has_related_synonym: pyroglutamyl aminopeptidase inhibitor
has_related_synonym: pyroglutamyl aminopeptidase inhibitors
has_related_synonym: pyroglutamyl-peptidase I (EC 3.4.19.3) inhibitor
has_related_synonym: pyroglutamyl-peptidase I (EC 3.4.19.3) inhibitors
has_related_synonym: pyroglutamyl-peptidase I inhibitor
has_related_synonym: pyroglutamyl-peptidase I inhibitors
has_related_synonym: pyrrolidone-carboxyl peptidase inhibitor
has_related_synonym: pyrrolidone-carboxyl peptidase inhibitors
has_related_synonym: pyrrolidonecarboxylyl peptidase inhibitor
has_related_synonym: pyrrolidonecarboxylyl peptidase inhibitors
has_related_synonym: pyrrolidonyl peptidase inhibitor
has_related_synonym: pyrrolidonyl peptidase inhibitors5-oxoprolyl-peptidase inhibitor
in_subset: 3 STAR
imported from: chebi.owl

nasal decongestant
type: Class
subclass of: drug
definition: A drug used to relieve nasal congestion in the upper respiratory tract.
id: CHEBI:77715
database_cross_reference: Wikipedia:Decongestant
has_obo_namespace: chebi_ontology
has_related_synonym: decongestant
has_related_synonym: decongestants
has_related_synonym: nasal decongestants
in_subset: 3 STAR
imported from: chebi.owl

p53 activator
type: Class
subclass of: activator
definition: Any activator of tumour protein p53.
id: CHEBI:77731
database_cross_reference: Wikipedia:P53
has_related_synonym: cellular tumor antigen p53 activator
has_related_synonym: cellular tumor antigen p53 activators
has_obo_namespace: chebi_ontology
has_related_synonym: p53 activators
has_related_synonym: phosphoprotein p53 activator
has_related_synonym: phosphoprotein p53 activators
has_related_synonym: tumor protein p53 activator
has_related_synonym: tumor protein p53 activators
has_related_synonym: tumour protein p53 activator
has_related_synonym: tumour protein p53 activators
has_related_synonym: tumour suppressor p53 activator
has_related_synonym: tumour suppressor p53 activators
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.24.18 (meprin A) inhibitor
type: Class
subclass of: EC 3.4.24.* (metalloendopeptidase) inhibitor
definition: An EC 3.4.24.* (metalloendopeptidase) inhibitor that inhibits the action of meprin A (EC 3.4.24.18).
id: CHEBI:77745
has_related_synonym: EC 3.4.24.18 (meprin A) inhibitors
has_related_synonym: EC 3.4.24.18 inhibitor
has_related_synonym: EC 3.4.24.18 inhibitors
has_related_synonym: N-benzoyl-L-tyrosyl-p-aminobenzoic acid hydrolase inhibitor
has_related_synonym: N-benzoyl-L-tyrosyl-p-aminobenzoic acid hydrolase inhibitors
has_related_synonym: PABA-peptide hydrolase inhibitor
has_related_synonym: PABA-peptide hydrolase inhibitors
has_related_synonym: PPH inhibitor
has_related_synonym: PPH inhibitors
database_cross_reference: Wikipedia:Meprin_A
has_obo_namespace: chebi_ontology
has_related_synonym: endopeptidase-2 inhibitor
has_related_synonym: endopeptidase-2 inhibitors
has_related_synonym: meprin A (EC 3.4.24.18) inhibitor
has_related_synonym: meprin A (EC 3.4.24.18) inhibitors
has_related_synonym: meprin A inhibitor
has_related_synonym: meprin A inhibitors
has_related_synonym: meprin inhibitor
has_related_synonym: meprin inhibitors
has_related_synonym: meprin-a inhibitor
has_related_synonym: meprin-a inhibitors
in_subset: 3 STAR
imported from: chebi.owl

human metabolite
type: Class
subclass of: mammalian metabolite
definition: Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
has_alternative_id: CHEBI:75770
has_alternative_id: CHEBI:77123
id: CHEBI:77746
has_related_synonym: H. sapiens metabolite
has_related_synonym: H. sapiens metabolites
has_related_synonym: Homo sapiens metabolite
has_related_synonym: Homo sapiens metabolites
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 3.6.3.1 (phospholipid-translocating ATPase) inhibitor
type: Class
subclass of: EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor
has_related_synonym: ATP phosphohydrolase (phospholipid-flipping) inhibitor
has_related_synonym: ATP phosphohydrolase (phospholipid-flipping) inhibitors
definition: An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of phospholipid-translocating ATPase (EC 3.6.3.1).
id: CHEBI:77747
has_related_synonym: EC 3.6.3.1 (phospholipid-translocating ATPase) inhibitors
has_related_synonym: EC 3.6.3.1 inhibitor
has_related_synonym: EC 3.6.3.1 inhibitors
has_related_synonym: Mg(2)(+)-ATPase inhibitor
has_related_synonym: Mg(2)(+)-ATPase inhibitors
database_cross_reference: Wikipedia:Phospholipid-translocating_ATPase
has_related_synonym: aminophospholipid-transporting ATPase inhibitor
has_related_synonym: aminophospholipid-transporting ATPase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: flippase inhibitor
has_related_synonym: flippase inhibitors
has_related_synonym: magnesium-ATPase inhibitor
has_related_synonym: magnesium-ATPase inhibitors
has_related_synonym: phospholipid-translocating ATPase (EC 3.6.3.1) inhibitor
has_related_synonym: phospholipid-translocating ATPase (EC 3.6.3.1) inhibitors
has_related_synonym: phospholipid-translocating ATPase inhibitor
has_related_synonym: phospholipid-translocating ATPase inhibitors
has_related_synonym: phospholipid-transporting ATPase inhibitor
has_related_synonym: phospholipid-transporting ATPase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor
type: Class
subclass of: EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor
has_related_synonym: ATP phosphohydrolase (steroid-exporting) inhibitor
has_related_synonym: ATP phosphohydrolase (steroid-exporting) inhibitors
has_related_synonym: ATP phosphohydrolase (xenobiotic-exporting) inhibitor
has_related_synonym: ATP phosphohydrolase (xenobiotic-exporting) inhibitors
definition: An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of xenobiotic-transporting ATPase (EC 3.6.3.44).
id: CHEBI:77748
has_related_synonym: EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitors
has_related_synonym: EC 3.6.3.44 inhibitor
has_related_synonym: EC 3.6.3.44 inhibitors
has_related_synonym: MDR protein inhibitor
has_related_synonym: MDR protein inhibitors
has_related_synonym: P-glycoprotein inhibitor
has_related_synonym: P-glycoprotein inhibitors
has_related_synonym: PDR protein inhibitor
has_related_synonym: PDR protein inhibitors
database_cross_reference: Wikipedia:Xenobiotic-transporting_ATPase
has_obo_namespace: chebi_ontology
has_related_synonym: multidrug-resistance protein inhibitor
has_related_synonym: multidrug-resistance protein inhibitors
has_related_synonym: pleiotropic-drug-resistance protein inhibitor
has_related_synonym: pleiotropic-drug-resistance protein inhibitors
has_related_synonym: steroid-transporting ATPase inhibitor
has_related_synonym: steroid-transporting ATPase inhibitors
has_related_synonym: xenobiotic-transporting ATPase (EC 3.6.3.44) inhibitor
has_related_synonym: xenobiotic-transporting ATPase (EC 3.6.3.44) inhibitors
has_related_synonym: xenobiotic-transporting ATPase inhibitor
has_related_synonym: xenobiotic-transporting ATPase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

ATP/ADP translocase inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
has_related_synonym: ATP-ADP translocase inhibitor
has_related_synonym: ATP-ADP translocase inhibitors
has_related_synonym: ATP/ADP translocase inhibitors
definition: Any inhibitor of the trasporter protein ATP/ADP translocase.
id: CHEBI:77750
database_cross_reference: Wikipedia:ATP-ADP_translocase
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 3.1.4.53 (3',5'-cyclic-AMP phosphodiesterase) inhibitor
type: Class
subclass of: EC 3.1.4.* (phosphoric diester hydrolase) inhibitor
has_related_synonym: 3',5'-cyclic-AMP 5'-nucleotidohydrolase inhibitor
has_related_synonym: 3',5'-cyclic-AMP 5'-nucleotidohydrolase inhibitors
has_related_synonym: 3',5'-cyclic-AMP phosphodiesterase (EC 3.1.4.53) inhibitor
has_related_synonym: 3',5'-cyclic-AMP phosphodiesterase (EC 3.1.4.53) inhibitors
has_related_synonym: 3',5'-cyclic-AMP phosphodiesterase inhibitor
has_related_synonym: 3',5'-cyclic-AMP phosphodiesterase inhibitors
definition: An EC 3.1.4.* (phosphoric diester hydrolase) inhibitor that interferes with the action of a 3',5'-cyclic-AMP phosphodiesterase (EC 3.1.4.53).
id: CHEBI:77758
has_related_synonym: EC 3.1.4.53 (3',5'-cyclic-AMP phosphodiesterase) inhibitors
has_related_synonym: EC 3.1.4.53 inhibitor
has_related_synonym: EC 3.1.4.53 inhibitors
database_cross_reference: Wikipedia:3',5'-cyclic-AMP_phosphodiesterase
has_related_synonym: cAMP-specific PDE inhibitor
has_related_synonym: cAMP-specific PDE inhibitors
has_related_synonym: cAMP-specific phosphodiesterase inhibitor
has_related_synonym: cAMP-specific phosphodiesterase inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 1.2.1.88 (L-glutamate gamma-semialdehyde dehydrogenase) inhibitor
type: Class
subclass of: EC 1.2.1.* (oxidoreductase acting on donor aldehyde/oxo group with NAD(+) or NADP(+) as acceptor) inhibitor
has_related_synonym: 1-pyrroline dehydrogenase inhibitor
has_related_synonym: 1-pyrroline dehydrogenase inhibitors
has_related_synonym: 1-pyrroline-5-carboxylate dehydrogenase inhibitor
has_related_synonym: 1-pyrroline-5-carboxylate dehydrogenase inhibitors
has_related_synonym: 1-pyrroline-5-carboxylate:NAD(+) oxidoreductase inhibitor
has_related_synonym: 1-pyrroline-5-carboxylate:NAD(+) oxidoreductase inhibitors
definition: An EC 1.2.1.* (oxidoreductase acting on donor aldehyde/oxo group with NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88).
id: CHEBI:77763
has_related_synonym: Delta(1)-pyrroline-5-carboxylate dehydrogenase inhibitor
has_related_synonym: Delta(1)-pyrroline-5-carboxylate dehydrogenase inhibitors
has_related_synonym: Delta(1)-pyrroline-5-carboxylic acid dehydrogenase inhibitor
has_related_synonym: Delta(1)-pyrroline-5-carboxylic acid dehydrogenase inhibitors
has_related_synonym: EC 1.2.1.88 (L-glutamate gamma-semialdehyde dehydrogenase) inhibitors
has_related_synonym: EC 1.2.1.88 inhibitor
has_related_synonym: EC 1.2.1.88 inhibitors
has_related_synonym: L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88) inhibitor
has_related_synonym: L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88) inhibitors
has_related_synonym: L-glutamate gamma-semialdehyde dehydrogenase inhibitor
has_related_synonym: L-glutamate gamma-semialdehyde dehydrogenase inhibitors
has_related_synonym: L-glutamate gamma-semialdehyde:NAD(+) oxidoreductase inhibitor
has_related_synonym: L-glutamate gamma-semialdehyde:NAD(+) oxidoreductase inhibitors
has_related_synonym: L-pyrroline-5-carboxylate-NAD(+) oxidoreductase inhibitor
has_related_synonym: L-pyrroline-5-carboxylate-NAD(+) oxidoreductase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: pyrroline-5-carboxylate dehydrogenase inhibitor
has_related_synonym: pyrroline-5-carboxylate dehydrogenase inhibitors
has_related_synonym: pyrroline-5-carboxylic acid dehydrogenase inhibitor
has_related_synonym: pyrroline-5-carboxylic acid dehydrogenase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

sulfaphenazole
type: Class
subclass of: molecular entity
charge: 0
has_related_synonym: 1-phenyl-5-sulfanilamidopyrazole
has_related_synonym: 3-(p-aminobenzenesulfonamido)-2-phenylpyrazole
monoisotopicmass: 314.08375
mass: 314.36200
has_exact_synonym: 4-amino-N-(1-phenyl-1H-pyrazol-5-yl)benzenesulfonamide
has_related_synonym: 5-sulfanilamido-1-phenylpyrazole
definition: A sulfonamide that is sulfanilamide in which the sulfonamide nitrogen is substituted by a 1-phenyl-1H-pyrazol-5-yl group. It is a selective inhibitor of cytochrome P450 (CYP) 2C9 isozyme, and antibacterial agent.
formula: C15H14N4O2S
database_cross_reference: CAS:526-08-9
id: CHEBI:77780
database_cross_reference: DrugBank:DB06729
database_cross_reference: Drug_Central:2523
database_cross_reference: HMDB:HMDB0015667
inchi: InChI=1S/C15H14N4O2S/c16-12-6-8-14(9-7-12)22(20,21)18-15-10-11-17-19(15)13-4-2-1-3-5-13/h1-11,18H,16H2
database_cross_reference: KEGG:D01954
database_cross_reference: LINCS:LSM-5279
has_related_synonym: N'-(1-phenylpyrazol-5-yl)sulfanilamide
has_related_synonym: N(1)-(1-phenylpyrazol-5-yl)sulfanilamide
smiles: Nc1ccc(cc1)S(=O)(=O)Nc1ccnn1-c1ccccc1
database_cross_reference: PMID:13873771
database_cross_reference: PMID:18845175
database_cross_reference: PMID:22785021
database_cross_reference: PMID:24519941
database_cross_reference: PMID:9864343
database_cross_reference: Patent:US2858309
inchikey: QWCJHSGMANYXCW-UHFFFAOYSA-N
database_cross_reference: Reaxys:308518
has_related_synonym: Sulfabid
database_cross_reference: Wikipedia:Sulfaphenazole
has_obo_namespace: chebi_ontology
has_related_synonym: sulfafenazol
has_related_synonym: sulfaphenazol
has_related_synonym: sulfaphenazole
has_related_synonym: sulfaphenazolum
has_related_synonym: sulphaphenazole
in_subset: 3 STAR
imported from: chebi.owl

EC 1.14.13.181 (13-deoxydaunorubicin hydroxylase) inhibitor
type: Class
subclass of: EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor
has_related_synonym: 13-deoxydaunorubicin hydroxylase (EC 1.14.13.181) inhibitor
has_related_synonym: 13-deoxydaunorubicin hydroxylase (EC 1.14.13.181) inhibitors
has_related_synonym: 13-deoxydaunorubicin hydroxylase inhibitor
has_related_synonym: 13-deoxydaunorubicin hydroxylase inhibitors
has_related_synonym: 13-deoxydaunorubicin,NADPH:oxygen oxidoreductase (13-hydroxylating) inhibitor
has_related_synonym: 13-deoxydaunorubicin,NADPH:oxygen oxidoreductase (13-hydroxylating) inhibitors
definition: An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of 13-deoxydaunorubicin hydroxylase (EC 1.14.13.181).
id: CHEBI:77781
has_related_synonym: DoxA inhibitor
has_related_synonym: DoxA inhibitors
has_related_synonym: EC 1.14.13.181 (13-deoxydaunorubicin hydroxylase) inhibitors
has_related_synonym: EC 1.14.13.181 inhibitor
has_related_synonym: EC 1.14.13.181 inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 1.14.13.67 (quinine 3-monooxygenase) inhibitor
type: Class
subclass of: EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor
definition: An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of quinine 3-monooxygenase (EC 1.14.13.67).
id: CHEBI:77783
has_related_synonym: EC 1.14.13.67 (quinine 3-monooxygenase) inhibitors
has_related_synonym: EC 1.14.13.67 inhibitor
has_related_synonym: EC 1.14.13.67 inhibitors
database_cross_reference: Wikipedia:Quinine_3-monooxygenase
has_obo_namespace: chebi_ontology
has_related_synonym: quinine 3-hydroxylase inhibitor
has_related_synonym: quinine 3-hydroxylase inhibitors
has_related_synonym: quinine 3-monooxygenase (EC 1.14.13.67) inhibitor
has_related_synonym: quinine 3-monooxygenase (EC 1.14.13.67) inhibitors
has_related_synonym: quinine 3-monooxygenase inhibitor
has_related_synonym: quinine 3-monooxygenase inhibitors
has_related_synonym: quinine,NADPH:oxygen oxidoreductase inhibitor
has_related_synonym: quinine,NADPH:oxygen oxidoreductase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

persistent organic pollutant
type: Class
subclass of: environmental contaminant
definition: Any environmental contaminant that is resistant to environmental degradation through photolytic, biological or chemical processes. Such substances can have significant impact on health and the environment, as they persist in the environment, bioaccumulate in animal tissue and so biomagnify in food chains.
id: CHEBI:77853
has_related_synonym: POP
has_related_synonym: POPs
database_cross_reference: Wikipedia:Persistant_organic_pollutant
has_obo_namespace: chebi_ontology
has_related_synonym: persistent organic pollutants
in_subset: 3 STAR
imported from: chebi.owl

EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor
type: Class
subclass of: EC 4.3.1.* (ammonia-lyase) inhibitor
has_related_synonym: 2,3-diaminopropanoate ammonia-lyase (adding H2O; pyruvate-forming) inhibitor
has_related_synonym: 2,3-diaminopropanoate ammonia-lyase (adding H2O; pyruvate-forming) inhibitors
has_related_synonym: 2,3-diaminopropanoate ammonia-lyase (adding water; pyruvate-forming) inhibitor
has_related_synonym: 2,3-diaminopropanoate ammonia-lyase (adding water; pyruvate-forming) inhibitors
has_related_synonym: 2,3-diaminopropanoate ammonia-lyase inhibitor
has_related_synonym: 2,3-diaminopropanoate ammonia-lyase inhibitors
has_related_synonym: 2,3-diaminopropionate ammonia-lyase inhibitor
has_related_synonym: 2,3-diaminopropionate ammonia-lyase inhibitors
definition: An EC 4.3.1.* (ammonia-lyase) inhibitor that interferes with the action of diaminopropionate ammonia-lyase (EC 4.3.1.15).
id: CHEBI:77881
has_related_synonym: EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitors
has_related_synonym: EC 4.3.1.15 inhibitor
has_related_synonym: EC 4.3.1.15 inhibitors
database_cross_reference: Wikipedia:Diaminopropionate_ammonia-lyase
has_related_synonym: alpha,beta-diaminopropionate ammonia-lyase inhibitor
has_related_synonym: alpha,beta-diaminopropionate ammonia-lyase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: diaminopropionatase inhibitor
has_related_synonym: diaminopropionatase inhibitors
has_related_synonym: diaminopropionate ammonia-lyase (EC 4.3.1.15) inhibitor
has_related_synonym: diaminopropionate ammonia-lyase (EC 4.3.1.15) inhibitors
has_related_synonym: diaminopropionate ammonia-lyase inhibitor
has_related_synonym: diaminopropionate ammonia-lyase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor
type: Class
subclass of: EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor
subclass of: sterol demethylation inhibitor
definition: An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of EC 1.14.13.70 (sterol 14alpha-demethylase).
id: CHEBI:77884
has_related_synonym: EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitors
has_related_synonym: EC 1.14.13.70 inhibitor
has_related_synonym: EC 1.14.13.70 inhibitors
database_cross_reference: Wikipedia:Sterol_14-demethylase
has_obo_namespace: chebi_ontology
has_related_synonym: cytochrome P450 51 inhibitor
has_related_synonym: cytochrome P450 51 inhibitors
has_related_synonym: lanosterol 14-demethylase inhibitor
has_related_synonym: lanosterol 14-demethylase inhibitors
has_related_synonym: lanosterol 14alpha-demethylase inhibitor
has_related_synonym: lanosterol 14alpha-demethylase inhibitors
has_related_synonym: obtusufoliol 14-demethylase inhibitor
has_related_synonym: obtusufoliol 14-demethylase inhibitors
has_related_synonym: sterol 14-demethylase inhibitor
has_related_synonym: sterol 14-demethylase inhibitors
has_related_synonym: sterol 14alpha-demethylase inhibitor
has_related_synonym: sterol 14alpha-demethylase inhibitors
has_related_synonym: sterol,NADPH:oxygen oxidoreductase (14-methyl cleaving) inhibitor
has_related_synonym: sterol,NADPH:oxygen oxidoreductase (14-methyl cleaving) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.5.1.4 (amidase) inhibitor
type: Class
subclass of: EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor
definition: An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of amidase (EC 3.5.1.4).
id: CHEBI:77941
has_related_synonym: EC 3.5.1.4 (amidase) inhibitors
has_related_synonym: EC 3.5.1.4 inhibitor
has_related_synonym: EC 3.5.1.4 inhibitors
has_related_synonym: N-acetylaminohydrolase inhibitor
has_related_synonym: N-acetylaminohydrolase inhibitors
database_cross_reference: Wikipedia:Amidase
has_related_synonym: acylamidase inhibitor
has_related_synonym: acylamidase inhibitors
has_related_synonym: acylamide amidohydrolase inhibitor
has_related_synonym: acylamide amidohydrolase inhibitors
has_related_synonym: amidase (EC 3.5.1.4) inhibitor
has_related_synonym: amidase (EC 3.5.1.4) inhibitors
has_related_synonym: amidase inhibitor
has_related_synonym: amidase inhibitors
has_related_synonym: amidohydrolase inhibitor
has_related_synonym: amidohydrolase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: deaminase inhibitor
has_related_synonym: deaminase inhibitors
has_related_synonym: fatty acylamidase inhibitor
has_related_synonym: fatty acylamidase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 6.1.1.4 (leucine--tRNA ligase) inhibitor
type: Class
subclass of: EC 6.1.1.* (ligases forming aminoacyl tRNA and related compounds) inhibitor
definition: An EC 6.1.1.* (ligases forming aminoacyl tRNA and related compounds) inhibitor that inhibits the action of leucine--tRNA synthetase (EC 6.1.1.4).
id: CHEBI:77953
has_related_synonym: EC 6.1.1.4 (leucine--tRNA ligase) inhibitors
has_related_synonym: EC 6.1.1.4 inhibitor
has_related_synonym: EC 6.1.1.4 inhibitors
has_related_synonym: L-leucine:tRNA(Leu) ligase (AMP-forming) inhibitor
has_related_synonym: L-leucine:tRNA(Leu) ligase (AMP-forming) inhibitors
database_cross_reference: Wikipedia:Leucyl-tRNA_synthetase
has_obo_namespace: chebi_ontology
has_related_synonym: leucine translase inhibitor
has_related_synonym: leucine translase inhibitors
has_related_synonym: leucine--tRNA ligase inhibitor
has_related_synonym: leucine--tRNA ligase inhibitors
has_related_synonym: leucine--tRNA synthetase inhibitor
has_related_synonym: leucine--tRNA synthetase inhibitors
has_related_synonym: leucyl--tRNA synthetase inhibitor
has_related_synonym: leucyl--tRNA synthetase inhibitors
has_related_synonym: leucyl-transfer RNA synthetase inhibitor
has_related_synonym: leucyl-transfer RNA synthetase inhibitors
has_related_synonym: leucyl-transfer ribonucleate synthetase inhibitor
has_related_synonym: leucyl-transfer ribonucleate synthetase inhibitors
has_related_synonym: leucyl-transfer ribonucleic acid synthetase inhibitor
has_related_synonym: leucyl-transfer ribonucleic acid synthetase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

food firming agent
type: Class
subclass of: food additive
definition: A food additive that is used to make or keep fruit or vegetable tissues firm and crisp. or which interacts with gelling agents such as pectin to produce or strengthen a gel.
id: CHEBI:77960
database_cross_reference: Wikipedia:Firming_agent
has_obo_namespace: chebi_ontology
has_related_synonym: firming agent
has_related_synonym: firming agents
has_related_synonym: food firming agents
in_subset: 3 STAR
imported from: chebi.owl

food antioxidant
type: Class
subclass of: antioxidant
subclass of: food preservative
definition: An antioxidant that used as a food additives to help guard against food deterioration.
id: CHEBI:77962
has_obo_namespace: chebi_ontology
has_related_synonym: food antioxidants
in_subset: 3 STAR
imported from: chebi.owl

sequestrant
type: Class
subclass of: chelator
subclass of: food preservative
definition: A food preservative that acts by chelating with metal cations (particularly those of copper, iron and nickel) that catalyse the oxidation of fats in food.
id: CHEBI:77963
database_cross_reference: Wikipedia:Sequestrant
has_obo_namespace: chebi_ontology
has_related_synonym: sequestrants
in_subset: 3 STAR
imported from: chebi.owl

anticaking agent
type: Class
subclass of: application
definition: A substance added to powdered or granulated materials in order to prevent the formation of lumps and so facilitate its packaging or transport.
id: CHEBI:77964
database_cross_reference: Wikipedia:Anti-caking_agent
has_related_synonym: anti-caking agent
has_related_synonym: anti-caking agents
has_related_synonym: anticaking agents
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

food anticaking agent
type: Class
subclass of: food additive
subclass of: anticaking agent
definition: An anticaking agent that is used to reduced the tendency of particles of food to adhere to one another.
id: CHEBI:77965
has_obo_namespace: chebi_ontology
has_related_synonym: food anti-caking agent
has_related_synonym: food anti-caking agents
has_exact_synonym: food anticaking agent
in_subset: 3 STAR
imported from: chebi.owl

food stabiliser
type: Class
subclass of: food additive
definition: A food additive that is used to preserve the structure of food.
id: CHEBI:77966
database_cross_reference: Wikipedia:Stabiliser_(food)
has_obo_namespace: chebi_ontology
has_related_synonym: food stabilisers
has_related_synonym: food stabilizer
has_related_synonym: food stabilizers
has_related_synonym: stabiliser
has_related_synonym: stabilisers
has_related_synonym: stabilizer
has_related_synonym: stabilizers
in_subset: 3 STAR
imported from: chebi.owl

humectant
type: Class
subclass of: application
definition: A compound that is used to keep a substance moist.
id: CHEBI:77968
database_cross_reference: Wikipedia:humectant
has_obo_namespace: chebi_ontology
has_related_synonym: humectants
in_subset: 3 STAR
imported from: chebi.owl

food humectant
type: Class
subclass of: food additive
subclass of: humectant
definition: A humectant that is used as a food additive to prevent foodstuffs from drying out.
id: CHEBI:77969
has_obo_namespace: chebi_ontology
has_related_synonym: food humectants
in_subset: 3 STAR
imported from: chebi.owl

food thickening agent
type: Class
subclass of: food additive
definition: A food additive that is used to increase the viscosity of foodstuffs.
id: CHEBI:77970
has_obo_namespace: chebi_ontology
has_related_synonym: food thickening agents
has_related_synonym: thickening agent
has_related_synonym: thickening agents
in_subset: 3 STAR
imported from: chebi.owl

raising agent
type: Class
subclass of: food additive
definition: A food additive which liberates gas so as to increase the volume of a dough or batter, resulting in a lighter and softer finished product.
id: CHEBI:77971
database_cross_reference: Wikipedia:Leavening_agent
has_obo_namespace: chebi_ontology
has_related_synonym: food raising agent
has_related_synonym: food raising agents
has_related_synonym: leavening agent
has_related_synonym: leavening agents
has_related_synonym: raising agents
in_subset: 3 STAR
imported from: chebi.owl

food glazing agent
type: Class
subclass of: food additive
definition: A food additive that is applied to the external surface or a food in order to give a smooth shiny appearance and/or to provide a protective coating to foodstuffs.
id: CHEBI:77972
database_cross_reference: Wikipedia:Glazing_agent
has_obo_namespace: chebi_ontology
has_related_synonym: food glazing agents
has_related_synonym: glazing agent
has_related_synonym: glazing agents
in_subset: 3 STAR
imported from: chebi.owl

antifoaming agent
type: Class
subclass of: application
definition: A substance that reduces and hinders the formation of foam in solutions and other liquids during their industrial or laboratory processing.
id: CHEBI:77973
database_cross_reference: Wikipedia:Defoamer
has_related_synonym: antifoaming agents
has_obo_namespace: chebi_ontology
has_related_synonym: defoamer
has_related_synonym: defoamers
in_subset: 3 STAR
imported from: chebi.owl

food packaging gas
type: Class
subclass of: food additive
definition: A food additive that is a (generally inert) gas which is used to envelop foodstuffs during packing and so protect them from unwanted chemical reactions such as food spoilage or oxidation during subsequent transport and storage. The term includes propellant gases, used to expel foods from a container.
id: CHEBI:77974
database_cross_reference: Wikipedia:Packaging_gas
has_obo_namespace: chebi_ontology
has_related_synonym: food packaging gases
in_subset: 3 STAR
imported from: chebi.owl

food bleaching agent
type: Class
subclass of: bleaching agent
subclass of: food additive
definition: A food additive that is used for the purpose of decolourising food.
id: CHEBI:78003
has_obo_namespace: chebi_ontology
has_related_synonym: food bleaching agents
in_subset: 3 STAR
imported from: chebi.owl

food bulking agent
type: Class
subclass of: food additive
definition: A food additive that contributes to the bulk of a food without significantly contributing to its available energy value.
id: CHEBI:78004
has_obo_namespace: chebi_ontology
has_related_synonym: filler
has_related_synonym: fillers
has_related_synonym: food bulking agents
in_subset: 3 STAR
imported from: chebi.owl

food colour retention agent
type: Class
subclass of: food additive
definition: A food additive that intensifies, retains or stabilises the colour of a food.
id: CHEBI:78006
database_cross_reference: Wikipedia:Colour_retention_agent
has_obo_namespace: chebi_ontology
has_related_synonym: color retention agent
has_related_synonym: color retention agents
has_related_synonym: colour retention agent
has_related_synonym: colour retention agents
has_related_synonym: food color retention agent
has_related_synonym: food color retention agents
has_related_synonym: food colour retention agents
in_subset: 3 STAR
imported from: chebi.owl

foaming agent
type: Class
subclass of: food additive
definition: A food additive that makes it possible to form or maintain a uniform dispersion of a gaseous phase in a liquid or solid phase.
id: CHEBI:78007
has_obo_namespace: chebi_ontology
has_related_synonym: foaming agents
in_subset: 3 STAR
imported from: chebi.owl

Wiskott-Aldrich syndrome protein inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
definition: Any inhibitor of Wiskott-Aldrich syndrome protein.
id: CHEBI:78009
has_related_synonym: N-WASP inhibitor
has_related_synonym: N-WASP inhibitors
has_related_synonym: WASP inhibitor
has_related_synonym: WASP inhibitors
database_cross_reference: Wikipedia:Wiskott-Aldrich_syndrome_protein
has_related_synonym: Wiskott-Aldrich syndrome protein inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

food gelling agent
type: Class
subclass of: food additive
definition: A food additive that enhances the texture of a foodstuff by gel formation.
id: CHEBI:78016
has_obo_namespace: chebi_ontology
has_related_synonym: food gelling agents
in_subset: 3 STAR
imported from: chebi.owl

food propellant
type: Class
subclass of: food additive
subclass of: propellant
definition: A propellant that is used to expel foods from an aerosol container.
id: CHEBI:78017
has_obo_namespace: chebi_ontology
has_related_synonym: food propellants
in_subset: 3 STAR
imported from: chebi.owl

EC 4.1.1.50 (adenosylmethionine decarboxylase) inhibitor
type: Class
subclass of: EC 4.1.1.* (carboxy-lyase) inhibitor
definition: An EC 4.1.1.* (carboxy-lyase) inhibitor that interferes with the action of adenosylmethionine decarboxylase (EC 4.1.1.50).
id: CHEBI:78024
has_related_synonym: EC 4.1.1.50 (adenosylmethionine decarboxylase) inhibitors
has_related_synonym: EC 4.1.1.50 inhibitor
has_related_synonym: EC 4.1.1.50 inhibitors
has_related_synonym: S-adenosyl-L-methionine carboxy-lyase [(5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium-salt-forming] inhibitor
has_related_synonym: S-adenosyl-L-methionine carboxy-lyase [(5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium-salt-forming] inhibitors
has_related_synonym: S-adenosyl-L-methionine carboxy-lyase [S-adenosyl 3-(methylthio)propylamine-forming] inhibitor
has_related_synonym: S-adenosyl-L-methionine carboxy-lyase [S-adenosyl 3-(methylthio)propylamine-forming] inhibitors
has_related_synonym: S-adenosyl-L-methionine carboxy-lyase inhibitor
has_related_synonym: S-adenosyl-L-methionine carboxy-lyase inhibitors
has_related_synonym: S-adenosyl-L-methionine decarboxylase inhibitor
has_related_synonym: S-adenosyl-L-methionine decarboxylase inhibitors
has_related_synonym: S-adenosylmethionine decarboxylase inhibitor
has_related_synonym: S-adenosylmethionine decarboxylase inhibitors
database_cross_reference: Wikipedia:Adenosylmethionine_decarboxylase
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

Wnt signalling inhibitor
type: Class
subclass of: inhibitor
definition: A substance that inhibits any of the Wnt signalling pathway, a group of signal transduction pathways made of proteins that pass signals from outside of a cell through cell surface receptors to the inside of the cell.
id: CHEBI:78031
has_related_synonym: Wnt signaling inhibitor
has_related_synonym: Wnt signaling inhibitors
has_related_synonym: Wnt signalling inhibitors
has_related_synonym: Wnt-signaling inhibitor
has_related_synonym: Wnt-signaling inhibitors
has_related_synonym: Wnt-signalling inhibitor
has_related_synonym: Wnt-signalling inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

food antifoaming agent
type: Class
subclass of: food additive
subclass of: antifoaming agent
definition: A food additive that is used to reduce or prevent foaming during the processing or manufacture of foodstuffs.
id: CHEBI:78058
has_obo_namespace: chebi_ontology
has_related_synonym: food antifoaming agents
has_related_synonym: food defoamer
has_related_synonym: food defoamers
in_subset: 3 STAR
imported from: chebi.owl

food additive carrier
type: Class
subclass of: food additive
definition: A food additive that is used to dilute, disperse or dissolve a food additive or nutrient without altering its function. Carriers are used to facilitate the handling or use of the food additive or nutrient.
has_alternative_id: CHEBI:78005
id: CHEBI:78059
has_related_synonym: carrier
has_related_synonym: carriers
has_obo_namespace: chebi_ontology
has_related_synonym: food additive carriers
in_subset: 3 STAR
imported from: chebi.owl

enzyme mimic
type: Class
subclass of: application
definition: Any small molecule that mimics the action of an enzyme.
id: CHEBI:78152
has_obo_namespace: chebi_ontology
has_related_synonym: enzyme mimetic
has_related_synonym: enzyme mimetics
has_related_synonym: enzyme mimics
in_subset: 3 STAR
imported from: chebi.owl

oxazepam
type: Class
subclass of: molecular entity
has_related_synonym: (+-)-Oxazepam
has_related_synonym: (RS)-Oxazepam
charge: 0
monoisotopicmass: 286.05091
mass: 286.71300
has_exact_synonym: 7-chloro-3-hydroxy-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one
definition: A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a hydroxy group at position 3 and phenyl group at position 5.
inchikey: ADIMAYPTOBDMTL-UHFFFAOYSA-N
formula: C15H11ClN2O2
database_cross_reference: CAS:604-75-1
id: CHEBI:7823
database_cross_reference: DrugBank:DB00842
database_cross_reference: Drug_Central:2015
database_cross_reference: HMDB:HMDB0014980
inchi: InChI=1S/C15H11ClN2O2/c16-10-6-7-12-11(8-10)13(9-4-2-1-3-5-9)18-15(20)14(19)17-12/h1-8,15,20H,(H,17,19)
database_cross_reference: KEGG:C07359
database_cross_reference: KEGG:D00464
smiles: OC1N=C(c2ccccc2)c2cc(Cl)ccc2NC1=O
has_exact_synonym: Oxazepam
database_cross_reference: PMID:17456431
database_cross_reference: PMID:9811432
database_cross_reference: Patent:CN1543961
database_cross_reference: Reaxys:754065
has_related_synonym: Serax
has_related_synonym: Tazepam
database_cross_reference: Wikipedia:Oxazepam
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

vitamin B1 antagonist
type: Class
subclass of: antagonist
definition: An antagonist which acts by inhibiting the action of vitamin B1
id: CHEBI:78248
has_obo_namespace: chebi_ontology
has_related_synonym: vitamin B1 antagonists
in_subset: 3 STAR
imported from: chebi.owl

food component
type: Class
subclass of: physiological role
definition: A physiological role played by any substance that is distributed in foodstuffs. It includes materials derived from plants or animals, such as vitamins or minerals, as well as environmental contaminants.
id: CHEBI:78295
has_obo_namespace: chebi_ontology
has_related_synonym: dietary component
has_related_synonym: dietary components
has_related_synonym: food components
in_subset: 3 STAR
imported from: chebi.owl

environmental contaminant
type: Class
subclass of: chemical role
definition: Any minor or unwanted substance introduced into the environment that can have undesired effects.
id: CHEBI:78298
has_obo_namespace: chebi_ontology
has_related_synonym: environmental contaminants
in_subset: 3 STAR
imported from: chebi.owl

environmental food contaminant
type: Class
subclass of: food component
subclass of: environmental contaminant
definition: Any unwanted chemical in food. The term includes agrochemicals and industrial chemicals that may contaminate foodstuffs during their production, transportation or storage.
id: CHEBI:78299
has_obo_namespace: chebi_ontology
has_related_synonym: environmental food contaminants
in_subset: 3 STAR
imported from: chebi.owl

lichen metabolite
type: Class
subclass of: metabolite
definition: Any metabolite that is produced during a metabolite reaction in lichens (composite organisms consisting of a fungus and a photosynthetic partner co-existing in a symbiotic relationship).
id: CHEBI:78361
has_obo_namespace: chebi_ontology
has_related_synonym: lichen metabolites
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.1.1 (hexokinase) inhibitor
type: Class
subclass of: lipid kinase inhibitor
subclass of: EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor
has_related_synonym: ATP-dependent hexokinase inhibitor
has_related_synonym: ATP-dependent hexokinase inhibitors
has_related_synonym: ATP:D-hexose 6-phosphotransferase inhibitor
has_related_synonym: ATP:D-hexose 6-phosphotransferase inhibitors
definition: An EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor that interferes with the action of hexokinase, EC 2.7.1.1, an enzyme that phosphorylates hexoses forming hexose phosphate.
id: CHEBI:78366
has_related_synonym: EC 2.7.1.1 (hexokinase) inhibitors
has_related_synonym: EC 2.7.1.1 inhibitor
has_related_synonym: EC 2.7.1.1 inhibitors
database_cross_reference: Wikipedia:Hexokinase
has_obo_namespace: chebi_ontology
has_related_synonym: glucose ATP phosphotransferase inhibitor
has_related_synonym: glucose ATP phosphotransferase inhibitors
has_related_synonym: hexokinase (phosphorylating) inhibitor
has_related_synonym: hexokinase (phosphorylating) inhibitors
has_related_synonym: hexokinase D inhibitor
has_related_synonym: hexokinase D inhibitors
has_related_synonym: hexokinase inhibitor
has_related_synonym: hexokinase inhibitors
has_related_synonym: hexokinase type I inhibitor
has_related_synonym: hexokinase type I inhibitors
has_related_synonym: hexokinase type II inhibitor
has_related_synonym: hexokinase type II inhibitors
has_related_synonym: hexokinase type III inhibitor
has_related_synonym: hexokinase type III inhibitors
has_related_synonym: hexokinase type IV glucokinase inhibitor
has_related_synonym: hexokinase type IV glucokinase inhibitors
has_related_synonym: hexokinase type IV inhibitor
has_related_synonym: hexokinase type IV inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.1.1.5 (lysophospholipase) inhibitor
type: Class
subclass of: EC 3.1.1.* (carboxylic ester hydrolase) inhibitor
has_related_synonym: 2-lysophosphatidylcholine acylhydrolase inhibitor
has_related_synonym: 2-lysophosphatidylcholine acylhydrolase inhibitors
definition: An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of the enzyme lysophospholipase (EC 3.1.1.5), which catalyses the release of fatty acids from lysophospholipids.
id: CHEBI:78372
has_related_synonym: EC 3.1.1.5 (lysophospholipase) inhibitors
has_related_synonym: EC 3.1.1.5 inhibitor
has_related_synonym: EC 3.1.1.5 inhibitors
has_related_synonym: NTE inhibitor
has_related_synonym: NTE inhibitors
has_related_synonym: NTE-LysoPLA inhibitor
has_related_synonym: NTE-LysoPLA inhibitors
has_related_synonym: NTE-lysophospholipase inhibitor
has_related_synonym: NTE-lysophospholipase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: lecithinase B inhibitor
has_related_synonym: lecithinase B inhibitors
has_related_synonym: lecitholipase inhibitor
has_related_synonym: lecitholipase inhibitors
has_related_synonym: lysolecithinase inhibitor
has_related_synonym: lysolecithinase inhibitors
has_related_synonym: lysophopholipase L2 inhibitor
has_related_synonym: lysophopholipase L2 inhibitors
has_related_synonym: lysophosphatidase inhibitor
has_related_synonym: lysophosphatidase inhibitors
has_related_synonym: lysophosphatidylcholine hydrolase inhibitor
has_related_synonym: lysophosphatidylcholine hydrolase inhibitors
has_related_synonym: lysophospholipase (EC 3.1.1.5) inhibitor
has_related_synonym: lysophospholipase (EC 3.1.1.5) inhibitors
has_related_synonym: lysophospholipase A1 inhibitor
has_related_synonym: lysophospholipase A1 inhibitors
has_related_synonym: lysophospholipase inhibitor
has_related_synonym: lysophospholipase inhibitors
has_related_synonym: lysophospholipase transacylase inhibitor
has_related_synonym: lysophospholipase transacylase inhibitors
has_related_synonym: neuropathy target esterase inhibitor
has_related_synonym: neuropathy target esterase inhibitors
has_related_synonym: phosphatidase B inhibitor
has_related_synonym: phosphatidase B inhibitors
has_related_synonym: phospholipase B inhibitor
has_related_synonym: phospholipase B inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor
type: Class
subclass of: EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor
has_related_synonym: 2-enoyl-CoA reductase inhibitor
has_related_synonym: 2-enoyl-CoA reductase inhibitors
definition: An EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of acyl-CoA dehydrogenase (NADP(+)), EC 1.3.1.8.
id: CHEBI:78377
has_related_synonym: EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitors
has_related_synonym: EC 1.3.1.8 inhibitor
has_related_synonym: EC 1.3.1.8 inhibitors
database_cross_reference: Wikipedia:Acyl-CoA_dehydrogenase_(NADP%2B)
has_related_synonym: acyl-CoA dehydrogenase (NADP(+)) (EC 1.3.1.8) inhibitor
has_related_synonym: acyl-CoA dehydrogenase (NADP(+)) (EC 1.3.1.8) inhibitors
has_related_synonym: acyl-CoA dehydrogenase (NADP(+)) inhibitor
has_related_synonym: acyl-CoA dehydrogenase (NADP(+)) inhibitors
has_related_synonym: acyl-CoA:NADP(+) 2-oxidoreductase inhibitor
has_related_synonym: acyl-CoA:NADP(+) 2-oxidoreductase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: crotonyl coenzyme A reductase inhibitor
has_related_synonym: crotonyl coenzyme A reductase inhibitors
has_related_synonym: crotonyl-CoA reductase inhibitor
has_related_synonym: crotonyl-CoA reductase inhibitors
has_related_synonym: dehydrogenase, acyl coenzyme A (nicotinamide adenine dinucleotide phosphate) inhibitor
has_related_synonym: dehydrogenase, acyl coenzyme A (nicotinamide adenine dinucleotide phosphate) inhibitors
has_related_synonym: enoyl coenzyme A reductase inhibitor
has_related_synonym: enoyl coenzyme A reductase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.5.1.7 (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) inhibitor
type: Class
subclass of: EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor
definition: An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC 2.5.1.7).
id: CHEBI:78379
has_related_synonym: EC 2.5.1.7 (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) inhibitors
has_related_synonym: EC 2.5.1.7 inhibitor
has_related_synonym: EC 2.5.1.7 inhibitors
has_related_synonym: MurA transferase inhibitor
has_related_synonym: MurA transferase inhibitors
has_related_synonym: UDP-N-acetylglucosamine 1-carboxyvinyl-transferase inhibitor
has_related_synonym: UDP-N-acetylglucosamine 1-carboxyvinyl-transferase inhibitors
has_related_synonym: UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC 2.5.1.7) inhibitor
has_related_synonym: UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC 2.5.1.7) inhibitors
has_related_synonym: UDP-N-acetylglucosamine 1-carboxyvinyltransferase inhibitor
has_related_synonym: UDP-N-acetylglucosamine 1-carboxyvinyltransferase inhibitors
has_related_synonym: UDP-N-acetylglucosamine enoylpyruvyltransferase inhibitor
has_related_synonym: UDP-N-acetylglucosamine enoylpyruvyltransferase inhibitors
database_cross_reference: Wikipedia:UDP-N-acetylglucosamine_1-carboxyvinyltransferase
has_obo_namespace: chebi_ontology
has_related_synonym: enoylpyruvate transferase inhibitor
has_related_synonym: enoylpyruvate transferase inhibitors
has_related_synonym: phosphoenolpyruvate-UDP-acetylglucosamine-3-enolpyruvyltransferase inhibitor
has_related_synonym: phosphoenolpyruvate-UDP-acetylglucosamine-3-enolpyruvyltransferase inhibitors
has_related_synonym: phosphoenolpyruvate:UDP-2-acetamido-2-deoxy-D-glucose 2-enoyl-1-carboxyethyltransferase inhibitor
has_related_synonym: phosphoenolpyruvate:UDP-2-acetamido-2-deoxy-D-glucose 2-enoyl-1-carboxyethyltransferase inhibitors
has_related_synonym: phosphoenolpyruvate:UDP-N-acetyl-D-glucosamine 1-carboxyvinyltransferase inhibitor
has_related_synonym: phosphoenolpyruvate:UDP-N-acetyl-D-glucosamine 1-carboxyvinyltransferase inhibitors
has_related_synonym: phosphoenolpyruvate:UDP-N-acetyl-alpha-D-glucosamine 1-carboxyvinyltransferase inhibitor
has_related_synonym: phosphoenolpyruvate:UDP-N-acetyl-alpha-D-glucosamine 1-carboxyvinyltransferase inhibitors
has_related_synonym: phosphoenolpyruvate:uridine diphosphate N-acetylglucosamine enolpyruvyltransferase inhibitor
has_related_synonym: phosphoenolpyruvate:uridine diphosphate N-acetylglucosamine enolpyruvyltransferase inhibitors
has_related_synonym: phosphoenolpyruvate:uridine-5'-diphospho-N-acetyl-2-amino-2-deoxyglucose 3-enolpyruvyltransferase inhibitor
has_related_synonym: phosphoenolpyruvate:uridine-5'-diphospho-N-acetyl-2-amino-2-deoxyglucose 3-enolpyruvyltransferase inhibitors
has_related_synonym: phosphopyruvate-uridine diphosphoacetylglucosamine pyruvatetransferase inhibitor
has_related_synonym: phosphopyruvate-uridine diphosphoacetylglucosamine pyruvatetransferase inhibitors
has_related_synonym: pyruvate-UDP-acetylglucosamine transferase inhibitor
has_related_synonym: pyruvate-UDP-acetylglucosamine transferase inhibitors
has_related_synonym: pyruvate-uridine diphospho-N-acetyl-glucosamine transferase inhibitor
has_related_synonym: pyruvate-uridine diphospho-N-acetyl-glucosamine transferase inhibitors
has_related_synonym: pyruvate-uridine diphospho-N-acetylglucosamine transferase inhibitor
has_related_synonym: pyruvate-uridine diphospho-N-acetylglucosamine transferase inhibitors
has_related_synonym: pyruvic-uridine diphospho-N-acetylglucosaminyltransferase inhibitor
has_related_synonym: pyruvic-uridine diphospho-N-acetylglucosaminyltransferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.5.4.1 (cytosine deaminase) inhibitor
type: Class
subclass of: EC 3.5.4.* (non-peptide cyclic amidine C-N hydrolase) inhibitor
definition: An EC 3.5.4.* (non-peptide cyclic amidine C-N hydrolase) inhibitor that interferes with the action of cytosine deaminase (EC 3.5.4.1).
id: CHEBI:78380
has_related_synonym: EC 3.5.4.1 (cytosine deaminase) inhibitors
has_related_synonym: EC 3.5.4.1 inhibitor
has_related_synonym: EC 3.5.4.1 inhibitors
database_cross_reference: Wikipedia:Cytosine_deaminase
has_obo_namespace: chebi_ontology
has_related_synonym: cytosine aminohydrolase inhibitor
has_related_synonym: cytosine aminohydrolase inhibitors
has_related_synonym: cytosine deaminase (EC 3.5.4.1) inhibitor
has_related_synonym: cytosine deaminase (EC 3.5.4.1) inhibitors
has_related_synonym: cytosine deaminase inhibitor
has_related_synonym: cytosine deaminase inhibitors
has_related_synonym: isocytosine deaminase inhibitor
has_related_synonym: isocytosine deaminase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 5.1.2.* (racemases acting on hydroxy acids and derivatives) inhibitor
type: Class
subclass of: EC 5.1.* (racemase/epimerase) inhibitor
definition: An EC 5.1.* (racemase/epimerase) inhibitor that interferes with the action of any such enzyme acting on hydroxy acids and their derivatives (EC 5.1.2.*).
id: CHEBI:78381
has_related_synonym: EC 5.1.2.* (racemases acting on hydroxy acids and derivatives) inhibitors
has_related_synonym: EC 5.1.2.* inhibitor
has_related_synonym: EC 5.1.2.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of racemases acting on hydroxy acids and derivatives
has_related_synonym: inhibitor of racemases acting on hydroxy acids and derivatives (EC 5.1.2.*)
has_related_synonym: inhibitors of racemases acting on hydroxy acids and derivatives
has_related_synonym: inhibitors of racemases acting on hydroxy acids and derivatives (EC 5.1.2.*)
in_subset: 3 STAR
imported from: chebi.owl

EC 5.1.3.* (racemases acting on carbohydrates and derivatives) inhibitor
type: Class
subclass of: EC 5.1.* (racemase/epimerase) inhibitor
definition: An EC 5.1.* (racemase/epimerase) inhibitor that interferes with the action of any such enzyme acting on carbohydrates and their derivatives (EC 5.1.3.*).
id: CHEBI:78382
has_related_synonym: EC 5.1.3.* (racemases acting on carbohydrates and derivatives) inhibitors
has_related_synonym: EC 5.1.3.* inhibitor
has_related_synonym: EC 5.1.3.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of racemases acting on carbohydrates and derivatives
has_related_synonym: inhibitor of racemases acting on carbohydrates and derivatives (EC 5.1.3.*)
has_related_synonym: inhibitors of racemases acting on carbohydrates and derivatives
has_related_synonym: inhibitors of racemases acting on carbohydrates and derivatives (EC 5.1.3.*)
in_subset: 3 STAR
imported from: chebi.owl

EC 5.1.99.* (racemases acting on other compounds) inhibitor
type: Class
subclass of: EC 5.1.* (racemase/epimerase) inhibitor
definition: An EC 5.1.* (racemase/epimerase) inhibitor that interferes with the action of any such enzyme acting compounds other than amino acids and their derivatives, hydroxy acids and their derivatives, or carbohydrates and their derivatives (EC 5.1.99.*).
id: CHEBI:78383
has_related_synonym: EC 5.1.99.* (racemases acting on other compounds) inhibitors
has_related_synonym: EC 5.1.99.* inhibitor
has_related_synonym: EC 5.1.99.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of racemases acting on other compounds (EC 5.1.99.*)
has_related_synonym: inhibitors of racemases acting on other compounds (EC 5.1.99.*)
in_subset: 3 STAR
imported from: chebi.owl

EC 5.1.3.2 (UDP-glucose 4-epimerase) inhibitor
type: Class
subclass of: EC 5.1.3.* (racemases acting on carbohydrates and derivatives) inhibitor
has_related_synonym: 4-epimerase inhibitor
has_related_synonym: 4-epimerase inhibitors
definition: An EC 5.1.3.* (racemases acting on carbohydrates and derivatives) inhibitor that interferes with the action of UDP-glucose 4-epimerase (EC 5.1.3.2).
id: CHEBI:78384
has_related_synonym: EC 5.1.3.2 (UDP-glucose 4-epimerase) inhibitors
has_related_synonym: EC 5.1.3.2 inhibitor
has_related_synonym: EC 5.1.3.2 inhibitors
has_related_synonym: UDP-D-galactose 4-epimerase inhibitor
has_related_synonym: UDP-D-galactose 4-epimerase inhibitors
has_related_synonym: UDP-alpha-D-glucose 4-epimerase inhibitor
has_related_synonym: UDP-alpha-D-glucose 4-epimerase inhibitors
has_related_synonym: UDP-galactose 4-epimerase inhibitor
has_related_synonym: UDP-galactose 4-epimerase inhibitors
has_related_synonym: UDP-glucose 4-epimerase (EC 5.1.3.2) inhibitor
has_related_synonym: UDP-glucose 4-epimerase (EC 5.1.3.2) inhibitors
has_related_synonym: UDP-glucose 4-epimerase inhibitor
has_related_synonym: UDP-glucose 4-epimerase inhibitors
has_related_synonym: UDP-glucose epimerase inhibitor
has_related_synonym: UDP-glucose epimerase inhibitors
has_related_synonym: UDPG-4-epimerase inhibitor
has_related_synonym: UDPG-4-epimerase inhibitors
has_related_synonym: UDPgalactose 4-epimerase inhibitor
has_related_synonym: UDPgalactose 4-epimerase inhibitors
has_related_synonym: UDPglucose 4-epimerase inhibitor
has_related_synonym: UDPglucose 4-epimerase inhibitors
database_cross_reference: Wikipedia:UDP-glucose_4-epimerase
has_obo_namespace: chebi_ontology
has_related_synonym: galactowaldenase inhibitor
has_related_synonym: galactowaldenase inhibitors
has_related_synonym: uridine diphosphate galactose 4-epimerase inhibitor
has_related_synonym: uridine diphosphate galactose 4-epimerase inhibitors
has_related_synonym: uridine diphosphate glucose 4-epimerase inhibitor
has_related_synonym: uridine diphosphate glucose 4-epimerase inhibitors
has_related_synonym: uridine diphospho-galactose-4-epimerase inhibitor
has_related_synonym: uridine diphospho-galactose-4-epimerase inhibitors
has_related_synonym: uridine diphosphoglucose 4-epimerase inhibitor
has_related_synonym: uridine diphosphoglucose 4-epimerase inhibitors
has_related_synonym: uridine diphosphoglucose epimerase inhibitor
has_related_synonym: uridine diphosphoglucose epimerase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

refrigerant
type: Class
subclass of: application
definition: A substance used in a thermodynamic heat pump cycle or refrigeration cycle that undergoes a phase change from a gas to a liquid and back. Refrigerants are used in air-conditioning systems and freezers or refrigerators and are assigned a "R" number (by ASHRAE - formerly the American Society of Heating, Refrigerating and Air Conditioning Engineers), which is determined systematically according to their molecular structure.
id: CHEBI:78433
database_cross_reference: Wikipedia:Refrigerant
has_obo_namespace: chebi_ontology
has_related_synonym: refrigerants
in_subset: 3 STAR
imported from: chebi.owl

EC 3.1.1.1 (carboxylesterase) inhibitor
type: Class
subclass of: EC 3.1.1.* (carboxylic ester hydrolase) inhibitor
has_related_synonym: Alpha-carboxylesterase inhibitor
has_related_synonym: Alpha-carboxylesterase inhibitors
definition: Any EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that inhibits the action of carboxylesterase (EC 3.1.1.1 ).
has_related_synonym: Beta-esterase inhibitor
has_related_synonym: Beta-esterase inhibitors
id: CHEBI:78444
has_related_synonym: EC 3.1.1.1 (carboxylesterase) inhibitors
has_related_synonym: ali-esterase inhibitor
has_related_synonym: ali-esterase inhibitors
has_related_synonym: butyrate esterase inhibitor
has_related_synonym: butyrate esterase inhibitors
has_related_synonym: butyryl esterase inhibitor
has_related_synonym: butyryl esterase inhibitors
has_related_synonym: carboxyl ester hydrolase inhibitor
has_related_synonym: carboxyl ester hydrolase inhibitors
has_related_synonym: carboxylate esterase inhibitor
has_related_synonym: carboxylate esterase inhibitors
has_related_synonym: carboxylesterase inhibitor
has_related_synonym: carboxylesterase inhibitors
has_related_synonym: carboxylic acid esterase inhibitor
has_related_synonym: carboxylic acid esterase inhibitors
has_related_synonym: carboxylic esterase inhibitor
has_related_synonym: carboxylic esterase inhibitors
has_related_synonym: carboxylic-ester hydrolase inhibitor
has_related_synonym: carboxylic-ester hydrolase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: cocaine esterase inhibitor
has_related_synonym: cocaine esterase inhibitors
has_related_synonym: esterase A inhibitor
has_related_synonym: esterase A inhibitors
has_related_synonym: esterase B inhibitor
has_related_synonym: esterase B inhibitors
has_related_synonym: esterase D inhibitor
has_related_synonym: esterase D inhibitors
has_related_synonym: methylbutyrase inhibitor
has_related_synonym: methylbutyrase inhibitors
has_related_synonym: methylbutyrate esterase inhibitor
has_related_synonym: methylbutyrate esterase inhibitors
has_related_synonym: monobutyrase inhibitor
has_related_synonym: monobutyrase inhibitors
has_related_synonym: nonspecific carboxylesterase inhibitor
has_related_synonym: nonspecific carboxylesterase inhibitors
has_related_synonym: procaine esterase inhibitor
has_related_synonym: procaine esterase inhibitors
has_related_synonym: propionyl esterase inhibitor
has_related_synonym: propionyl esterase inhibitors
has_related_synonym: serine esterase inhibitor
has_related_synonym: serine esterase inhibitors
has_related_synonym: triacetin esterase inhibitor
has_related_synonym: triacetin esterase inhibitors
has_related_synonym: vitamin A esterase inhibitor
has_related_synonym: vitamin A esterase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

venom
type: Class
subclass of: toxin
definition: A toxin used by animals and injected into their victims by a bite or sting.
id: CHEBI:78505
database_cross_reference: Wikipedia:Venom
has_obo_namespace: chebi_ontology
has_related_synonym: venoms
in_subset: 3 STAR
imported from: chebi.owl

protein kinase A agonist
type: Class
subclass of: protein kinase agonist
definition: A protein kinase agonist that selectively binds to and activates a protein kinase A receptor
id: CHEBI:78547
has_obo_namespace: chebi_ontology
has_related_synonym: protein kinase A agonists
in_subset: 3 STAR
imported from: chebi.owl

adenylate cyclase agonist
type: Class
subclass of: agonist
definition: Any agonist of one or more of the isoforms of adenylate cyclase (EC 4.6.1.1).
id: CHEBI:78548
has_related_synonym: adenylate cyclase agonists
has_related_synonym: adenylyl cyclase agonist
has_related_synonym: adenylyl cyclase agonists
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

vesicant
type: Class
subclass of: biophysical role
definition: Any compound that causes severe skin, eye and mucosal pain and irritation.
id: CHEBI:78592
database_cross_reference: PMID:16168310
database_cross_reference: Wikipedia:Blister_agent
has_related_synonym: blister agent
has_related_synonym: blister agents
has_obo_namespace: chebi_ontology
has_related_synonym: vesicants
in_subset: 3 STAR
imported from: chebi.owl

Hsp70 inducer
type: Class
subclass of: activator
definition: Any inducer of heat shock protein 70.
id: CHEBI:78606
has_related_synonym: Hsp70 activator
has_related_synonym: Hsp70 activators
has_related_synonym: Hsp70 inducers
database_cross_reference: Wikipedia:Hsp70
has_obo_namespace: chebi_ontology
has_related_synonym: heat shock protein 70 activator
has_related_synonym: heat shock protein 70 activators
has_related_synonym: heat shock protein 70 inducer
has_related_synonym: heat shock protein 70 inducers
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.11.31 {[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase} inhibitor
type: Class
subclass of: EC 2.7.11.* (protein-serine/threonine kinase) inhibitor
has_related_synonym: 3-hydroxy-3-methylglutaryl coenzyme A reductase kinase inhibitor
has_related_synonym: 3-hydroxy-3-methylglutaryl coenzyme A reductase kinase inhibitors
has_related_synonym: 3-hydroxy-3-methylglutaryl-CoA reductase kinase inhibitor
has_related_synonym: 3-hydroxy-3-methylglutaryl-CoA reductase kinase inhibitors
has_related_synonym: AMP-activated protein kinase inhibitor
has_related_synonym: AMP-activated protein kinase inhibitors
has_related_synonym: AMPK inhibitor
has_related_synonym: AMPK inhibitors
has_related_synonym: ATP:[hydroxymethylglutaryl-CoA reductase (NADPH)] phosphotransferase inhibitor
has_related_synonym: ATP:[hydroxymethylglutaryl-CoA reductase (NADPH)] phosphotransferase inhibitors
definition: An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of any [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase (EC 2.7.11.31).
id: CHEBI:78622
has_related_synonym: EC 2.7.11.31 ([hydroxymethylglutaryl-CoA reductase (NADPH)] kinase) inhibitor
has_related_synonym: EC 2.7.11.31 ([hydroxymethylglutaryl-CoA reductase (NADPH)] kinase) inhibitors
has_related_synonym: EC 2.7.11.31 inhibitor
has_related_synonym: EC 2.7.11.31 inhibitors
has_related_synonym: EC 2.7.11.31 {[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase} inhibitors
has_related_synonym: HMG-CoA reductase kinase inhibitor
has_related_synonym: HMG-CoA reductase kinase inhibitors
has_related_synonym: STK29 inhibitor
has_related_synonym: STK29 inhibitors
database_cross_reference: Wikipedia:AMP-activated_protein_kinase
has_related_synonym: [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase inhibitor
has_related_synonym: [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase inhibitors
has_related_synonym: [hydroxymethylglutaryl-CoA reductase (NADPH2)] kinase inhibitor
has_related_synonym: [hydroxymethylglutaryl-CoA reductase (NADPH2)] kinase inhibitors
has_related_synonym: beta-hydroxy-beta-methylglutaryl-CoA reductase kinase inhibitor
has_related_synonym: beta-hydroxy-beta-methylglutaryl-CoA reductase kinase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: hydroxymethylglutaryl coenzyme A reductase kinase (phosphorylating) inhibitor
has_related_synonym: hydroxymethylglutaryl coenzyme A reductase kinase (phosphorylating) inhibitors
has_related_synonym: hydroxymethylglutaryl coenzyme A reductase kinase inhibitor
has_related_synonym: hydroxymethylglutaryl coenzyme A reductase kinase inhibitors
has_related_synonym: hydroxymethylglutaryl-CoA reductase kinase inhibitor
has_related_synonym: hydroxymethylglutaryl-CoA reductase kinase inhibitors
has_related_synonym: reductase kinase inhibitor
has_related_synonym: reductase kinase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

bone morphogenetic protein receptor antagonist
type: Class
subclass of: antagonist
definition: An antagonist at the bone morphogenetic protein receptor.
has_related_synonym: BMP antagonist
has_related_synonym: BMP antagonists
has_related_synonym: BMP receptor inhibitor
has_related_synonym: BMP receptor inhibitors
id: CHEBI:78623
has_related_synonym: bone morphogenetic protein antagonists
has_related_synonym: bone morphogenetic protein inhibitor
has_related_synonym: bone morphogenetic protein receptor inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

fundamental metabolite
type: Class
subclass of: metabolite
definition: Any metabolite produced by all living cells.
id: CHEBI:78675
has_obo_namespace: chebi_ontology
has_related_synonym: essential metabolite
has_related_synonym: essential metabolites
has_related_synonym: fundamental metabolites
in_subset: 3 STAR
imported from: chebi.owl

EC 4.6.1.2 (guanylate cyclase) inhibitor
type: Class
subclass of: EC 4.6.* (P-O lyase) inhibitor
definition: An EC 4.6.* (P-O lyase) inhibitor that interferes with the action of enzyme guanylate cyclase (EC 4.6.1.2).
id: CHEBI:78678
has_related_synonym: EC 4.6.1.2 (guanylate cyclase) inhibitors
has_related_synonym: EC 4.6.1.2 inhibitor
has_related_synonym: EC 4.6.1.2 inhibitors
has_related_synonym: GTP diphosphate-lyase (cyclizing) inhibitor
has_related_synonym: GTP diphosphate-lyase (cyclizing) inhibitors
has_related_synonym: GTP diphosphate-lyase (cyclizing; 3',5'-cyclic-GMP-forming) inhibitor
has_related_synonym: GTP diphosphate-lyase (cyclizing; 3',5'-cyclic-GMP-forming) inhibitors
database_cross_reference: Wikipedia:Guanylate_cyclase
has_obo_namespace: chebi_ontology
has_related_synonym: guanyl cyclase inhibitor
has_related_synonym: guanyl cyclase inhibitors
has_related_synonym: guanylyl cyclase inhibitor
has_related_synonym: guanylyl cyclase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

tropomyosin-related kinase B receptor antagonist
type: Class
subclass of: antagonist
definition: An antagonist that binds to and deactivates the tropomyosin-related kinase B (TrkB) receptor, the main signaling receptor of the neurotrophin brain-derived neurotrophic factor (BDNF).
id: CHEBI:78681
has_related_synonym: TrkB receptor antagonist
has_related_synonym: TrkB receptor antagonists
has_obo_namespace: chebi_ontology
has_related_synonym: tropomyosin-related kinase B receptor antagonists
in_subset: 3 STAR
imported from: chebi.owl

EC 2.3.1.97 (glycylpeptide N-tetradecanoyltransferase) inhibitor
type: Class
subclass of: EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor
definition: An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of glycylpeptide N-tetradecanoyltransferase (EC 2.3.1.97).
id: CHEBI:78691
has_related_synonym: EC 2.3.1.97 (glycylpeptide N-tetradecanoyltransferase) inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: myristoyl-CoA-protein N-myristoyltransferase inhibitor
has_related_synonym: myristoyl-CoA-protein N-myristoyltransferase inhibitors
has_related_synonym: myristoyl-coenzyme A:protein N-myristoyl transferase inhibitor
has_related_synonym: myristoyl-coenzyme A:protein N-myristoyl transferase inhibitors
has_related_synonym: peptide N-myristoyltransferase inhibitor
has_related_synonym: peptide N-myristoyltransferase inhibitors
has_related_synonym: protein N-myristoyltransferase inhibitor
has_related_synonym: protein N-myristoyltransferase inhibitors
has_related_synonym: tetradecanoyl-CoA:glycylpeptide N-tetradecanoyltransferase inhibitor
has_related_synonym: tetradecanoyl-CoA:glycylpeptide N-tetradecanoyltransferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.3.1.72 (Delta(24)-sterol reductase) inhibitor
type: Class
subclass of: EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor
definition: An EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of Delta(24)-sterol reductase (EC 1.3.1.72).
id: CHEBI:78728
has_related_synonym: Delta(24)-sterol reductase (EC 1.3.1.72) inhibitor
has_related_synonym: Delta(24)-sterol reductase (EC 1.3.1.72) inhibitors
has_related_synonym: Delta(24)-sterol reductase inhibitor
has_related_synonym: Delta(24)-sterol reductase inhibitors
has_related_synonym: EC 1.3.1.72 (Delta(24)-sterol reductase) inhibitors
has_related_synonym: EC 1.3.1.72 inhibitor
has_related_synonym: EC 1.3.1.72 inhibitors
database_cross_reference: Wikipedia:Delta24-sterol_reductase
has_obo_namespace: chebi_ontology
has_related_synonym: lanosterol Delta (24)-reductase
has_related_synonym: sterol:NADP(+) Delta(24)-oxidoreductase
in_subset: 3 STAR
imported from: chebi.owl

EC 2.5.1.6 (methionine adenosyltransferase) inhibitor
type: Class
subclass of: EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor
has_related_synonym: ATP-methionine adenosyltransferase inhibitor
has_related_synonym: ATP-methionine adenosyltransferase inhibitors
has_related_synonym: ATP:L-methionine S-adenosyltransferase inhibitor
has_related_synonym: ATP:L-methionine S-adenosyltransferase inhibitors
has_related_synonym: AdoMet synthetase inhibitor
has_related_synonym: AdoMet synthetase inhibitors
definition: An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of methionine adenosyltransferase (EC 2.5.1.6).
id: CHEBI:78756
has_related_synonym: EC 2.5.1.6 (methionine adenosyltransferase) inhibitors
has_related_synonym: EC 2.5.1.6 inhibitor
has_related_synonym: EC 2.5.1.6 inhibitors
has_related_synonym: S-adenosyl-L-methionine synthetase inhibitor
has_related_synonym: S-adenosyl-L-methionine synthetase inhibitors
has_related_synonym: S-adenosylmethionine synthase inhibitor
has_related_synonym: S-adenosylmethionine synthase inhibitors
has_related_synonym: S-adenosylmethionine synthetase inhibitor
has_related_synonym: S-adenosylmethionine synthetase inhibitors
database_cross_reference: Wikipedia:S-adenosylmethionine_synthetase_enzyme
has_related_synonym: adenosylmethionine synthetase inhibitor
has_related_synonym: adenosylmethionine synthetase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: methionine S-adenosyltransferase inhibitor
has_related_synonym: methionine S-adenosyltransferase inhibitors
has_related_synonym: methionine-activating enzyme inhibitor
has_related_synonym: methionine-activating enzyme inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.1.91 (sphingosine kinase) inhibitor
type: Class
subclass of: EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor
has_related_synonym: ATP:sphinganine 1-phosphotransferase inhibitor
has_related_synonym: ATP:sphinganine 1-phosphotransferase inhibitors
definition: An EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor that interferes with the action of sphinganine kinase (EC 2.7.1.91).
id: CHEBI:78760
has_related_synonym: EC 2.7.1.91 (sphinganine kinase) inhibitor
has_related_synonym: EC 2.7.1.91 (sphinganine kinase) inhibitors
has_related_synonym: EC 2.7.1.91 (sphingosine kinase) inhibitors
has_related_synonym: EC 2.7.1.91 inhibitor
has_related_synonym: EC 2.7.1.91 inhibitors
has_related_synonym: SGK inhibitor
has_related_synonym: SGK inhibitors
has_related_synonym: SK inhibitor
has_related_synonym: SK inhibitors
database_cross_reference: Wikipedia:Sphingosine_kinase
has_obo_namespace: chebi_ontology
has_related_synonym: dihydrosphingosine kinase (phosphorylating) inhibitor
has_related_synonym: dihydrosphingosine kinase (phosphorylating) inhibitors
has_related_synonym: dihydrosphingosine kinase inhibitor
has_related_synonym: dihydrosphingosine kinase inhibitors
has_related_synonym: sphinganine kinase inhibitor
has_related_synonym: sphinganine kinase inhibitors
has_related_synonym: sphingoid base kinase inhibitor
has_related_synonym: sphingoid base kinase inhibitors
has_related_synonym: sphingosine kinase (phosphorylating) inhibitor
has_related_synonym: sphingosine kinase (phosphorylating) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.11.18 (myosin-light-chain kinase) inhibitor
type: Class
subclass of: EC 2.7.11.* (protein-serine/threonine kinase) inhibitor
has_related_synonym: ATP:[myosin-light-chain] O-phosphotransferase inhibitor
has_related_synonym: ATP:[myosin-light-chain] O-phosphotransferase inhibitors
has_related_synonym: ATP:myosin-light-chain O-phosphotransferase inhibitor
has_related_synonym: ATP:myosin-light-chain O-phosphotransferase inhibitors
definition: An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of myosin-light-chain kinase (EC 2.7.11.18).
id: CHEBI:78763
has_related_synonym: EC 2.7.11.18 (myosin-light-chain kinase) inhibitors
has_related_synonym: EC 2.7.11.18 inhibitor
has_related_synonym: EC 2.7.11.18 inhibitors
has_related_synonym: MLCK inhibitor
has_related_synonym: MLCK inhibitors
has_related_synonym: MLCkase inhibitor
has_related_synonym: MLCkase inhibitors
database_cross_reference: Wikipedia:Myosin_light-chain_kinase
has_related_synonym: [myosin-light-chain] kinase inhibitor
has_related_synonym: [myosin-light-chain] kinase inhibitors
has_related_synonym: calcium/calmodulin-dependent myosin light chain kinase inhibitor
has_related_synonym: calcium/calmodulin-dependent myosin light chain kinase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: myosin kinase inhibitor
has_related_synonym: myosin kinase inhibitors
has_related_synonym: myosin light chain kinase inhibitor
has_related_synonym: myosin light chain kinase inhibitors
has_related_synonym: myosin light chain protein kinase inhibitor
has_related_synonym: myosin light chain protein kinase inhibitors
has_related_synonym: myosin light-chain kinase (phosphorylating) inhibitor
has_related_synonym: myosin light-chain kinase (phosphorylating) inhibitors
has_related_synonym: myosin light-chain kinase inhibitor
has_related_synonym: myosin light-chain kinase inhibitors
has_related_synonym: myosin-light-chain kinase (EC 2.7.11.18) inhibitor
has_related_synonym: myosin-light-chain kinase (EC 2.7.11.18) inhibitors
has_related_synonym: myosin-light-chain kinase inhibitor
has_related_synonym: myosin-light-chain kinase inhibitors
has_related_synonym: smooth-muscle-myosin-light-chain kinase inhibitor
has_related_synonym: smooth-muscle-myosin-light-chain kinase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

nematode metabolite
type: Class
subclass of: animal metabolite
definition: An animal metabolite produced by any member of the phylum Nematoda.
id: CHEBI:78803
has_obo_namespace: chebi_ontology
has_related_synonym: nematode metabolites
in_subset: 3 STAR
imported from: chebi.owl

Caenorhabditis elegans metabolite
type: Class
subclass of: nematode metabolite
definition: A nematode metabolite produced by Caenorhabditis elegans.
has_related_synonym: C. elegans metabolite
has_related_synonym: C. elegans metabolites
id: CHEBI:78804
has_related_synonym: Caenorhabditis elegans metabolites
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

survivin dimerisation modulator
type: Class
subclass of: pharmacological role
definition: Any compound that affects the dimerisation of the protein survivin.
id: CHEBI:78926
database_cross_reference: PMID:23968825
database_cross_reference: PMID:26924735
database_cross_reference: Patent:FR2955113
has_obo_namespace: chebi_ontology
has_related_synonym: survivin dimerisation modulators
has_related_synonym: survivin modulator
has_related_synonym: survivin modulators
in_subset: 3 STAR
imported from: chebi.owl

EC 3.6.1.* (hydrolases acting on acid anhydrides in P-containing anhydrides) inhibitor
type: Class
subclass of: EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor
definition: Any EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor that interferes with the action of any such enzyme acting on phosphorus-containing anhydrides.
id: CHEBI:78927
has_related_synonym: EC 3.6.1.* (hydrolases acting on acid anhydrides in P-containing anhydrides) inhibitors
has_related_synonym: EC 3.6.1.* (hydrolases acting on acid anhydrides in phosphorus-containing anhydrides) inhibitor
has_related_synonym: EC 3.6.1.* (hydrolases acting on acid anhydrides in phosphorus-containing anhydrides) inhibitors
has_related_synonym: EC 3.6.1.* inhibitor
has_related_synonym: EC 3.6.1.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: hydrolases acting on acid anhydrides in P-containing anhydrides (EC 3.6.1.*) inhibitor
has_related_synonym: hydrolases acting on acid anhydrides in P-containing anhydrides (EC 3.6.1.*) inhibitors
has_related_synonym: hydrolases acting on acid anhydrides in phosphorus-containing anhydrides (EC 3.6.1.*) inhibitor
has_related_synonym: hydrolases acting on acid anhydrides in phosphorus-containing anhydrides (EC 3.6.1.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.6.1.3 (adenosinetriphosphatase) inhibitor
type: Class
subclass of: EC 3.6.1.* (hydrolases acting on acid anhydrides in P-containing anhydrides) inhibitor
has_related_synonym: (Ca(2+) + Mg(2+))-ATPase inhibitor
has_related_synonym: (Ca(2+) + Mg(2+))-ATPase inhibitors
has_related_synonym: ATP hydrolase inhibitor
has_related_synonym: ATP hydrolase inhibitors
has_related_synonym: ATP monophosphatase inhibitor
has_related_synonym: ATP monophosphatase inhibitors
has_related_synonym: ATP phosphohydrolase inhibitor
has_related_synonym: ATP phosphohydrolase inhibitors
has_related_synonym: ATPase inhibitor
has_related_synonym: ATPase inhibitors
definition: An EC 3.6.1.* (hydrolases acting on acid anhydrides in P-containing anhydrides) inhibitor that interferes with the action of adenosinetriphosphatase (EC 3.6.1.3).
id: CHEBI:78928
has_related_synonym: EC 3.6.1.3 (adenosinetriphosphatase) inhibitors
has_related_synonym: EC 3.6.1.3 inhibitor
has_related_synonym: EC 3.6.1.3 inhibitors
has_related_synonym: HCO3(-)-ATPase inhibitor
has_related_synonym: HCO3(-)-ATPase inhibitors
has_related_synonym: SV40 T-antigen inhibitor
has_related_synonym: SV40 T-antigen inhibitors
database_cross_reference: Wikipedia:ATPase
has_related_synonym: adenosine 5'-triphosphatase inhibitor
has_related_synonym: adenosine 5'-triphosphatase inhibitors
has_related_synonym: adenosine triphosphatase inhibitor
has_related_synonym: adenosine triphosphatase inhibitors
has_related_synonym: adenosinetriphosphatase (EC 3.6.1.3) inhibitor
has_related_synonym: adenosinetriphosphatase (EC 3.6.1.3) inhibitors
has_related_synonym: adenosinetriphosphatase inhibitor
has_related_synonym: adenosinetriphosphatase inhibitors
has_related_synonym: adenylpyrophosphatase inhibitor
has_related_synonym: adenylpyrophosphatase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: complex V (mitochondrial electron transport) inhibitor
has_related_synonym: complex V (mitochondrial electron transport) inhibitors
has_related_synonym: triphosphatase inhibitor
has_related_synonym: triphosphatase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

archaeal metabolite
type: Class
subclass of: prokaryotic metabolite
definition: Any prokaryotic metabolite produced during a metabolic reaction in single-celled microorganisms, archaea.
id: CHEBI:78947
has_related_synonym: archaeal metabolites
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

melatonin receptor agonist
type: Class
subclass of: agonist
definition: An agonist that binds to and activates melatonin receptors.
id: CHEBI:79046
database_cross_reference: Wikipedia:Melatonin_receptor_agonist
has_obo_namespace: chebi_ontology
has_related_synonym: melatonin receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.22.52 (calpain-1) inhibitor
type: Class
subclass of: calpain inhibitor
definition: A calpain inhibitor that interferes with the action of calpain-1 (EC 3.4.22.52).
id: CHEBI:79050
has_related_synonym: EC 3.4.22.52 (calpain-1) inhibitors
has_related_synonym: EC 3.4.22.52 inhibitor
has_related_synonym: EC 3.4.22.52 inhibitors
database_cross_reference: Wikipedia:Calpain-1
has_related_synonym: calcium-activated neutral protease I inhibitor
has_related_synonym: calcium-activated neutral protease I inhibitors
has_related_synonym: calpain-1 (EC 3.4.22.52) inhibitor
has_related_synonym: calpain-1 (EC 3.4.22.52) inhibitors
has_related_synonym: calpain-1 inhibitor
has_related_synonym: calpain-1 inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: mu-calpain inhibitor
has_related_synonym: mu-calpain inhibitors
in_subset: 3 STAR
imported from: chebi.owl

plasticiser
type: Class
subclass of: application
definition: Any compound that is used as an additive to increase the plasticity or fluidity of a substance, particularly but not exclusively to synthetic polymers.
id: CHEBI:79056
database_cross_reference: Wikipedia:Plasticizer
has_obo_namespace: chebi_ontology
has_related_synonym: plasticisers
has_related_synonym: plasticizer
has_related_synonym: plasticizers
in_subset: 3 STAR
imported from: chebi.owl

potassium channel opener
type: Class
subclass of: potassium channel modulator
definition: A potassium channel modulator that opens the potassium channel.
id: CHEBI:79085
database_cross_reference: Wikipedia:Potassium_channel_opener
has_obo_namespace: chebi_ontology
has_related_synonym: potassium channel activator
has_related_synonym: potassium channel activators
has_related_synonym: potassium channel agonist
has_related_synonym: potassium channel agonists
has_related_synonym: potassium channel openers
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.24.35 (gelatinase B) inhibitor
type: Class
subclass of: matrix metalloproteinase inhibitor
subclass of: EC 3.4.24.* (metalloendopeptidase) inhibitor
has_related_synonym: 92-kDa gelatinase inhibitor
has_related_synonym: 92-kDa gelatinase inhibitors
has_related_synonym: 92-kDa type IV collagenase inhibitor
has_related_synonym: 92-kDa type IV collagenase inhibitors
has_related_synonym: 95 kDa type IV collagenase/gelatinase inhibitor
has_related_synonym: 95 kDa type IV collagenase/gelatinase inhibitors
definition: An EC 3.4.24.* (metalloendopeptidase) inhibitor that interferes with the action of gelatinase B (EC 3.4.24.35).
id: CHEBI:79088
has_related_synonym: EC 3.4.24.35 (gelatinase B) inhibitors
has_related_synonym: EC 3.4.24.35 inhibitor
has_related_synonym: EC 3.4.24.35 inhibitors
has_related_synonym: MMP 9 inhibitor
has_related_synonym: MMP 9 inhibitors
database_cross_reference: Wikipedia:Gelatinase_B
has_obo_namespace: chebi_ontology
has_related_synonym: collagenase IV inhibitor
has_related_synonym: collagenase IV inhibitors
has_related_synonym: collagenase type IV inhibitor
has_related_synonym: collagenase type IV inhibitors
has_related_synonym: gelatinase B (EC 3.4.24.35) inhibitor
has_related_synonym: gelatinase B (EC 3.4.24.35) inhibitors
has_related_synonym: gelatinase B inhibitor
has_related_synonym: gelatinase B inhibitors
has_related_synonym: gelatinase MMP 9 inhibitor
has_related_synonym: gelatinase MMP 9 inhibitors
has_related_synonym: macrophage gelatinase inhibitor
has_related_synonym: macrophage gelatinase inhibitors
has_related_synonym: matrix metalloproteinase 9 inhibitor
has_related_synonym: matrix metalloproteinase 9 inhibitors
has_related_synonym: type IV collagen metalloproteinase inhibitor
has_related_synonym: type IV collagen metalloproteinase inhibitors
has_related_synonym: type V collagenase inhibitor
has_related_synonym: type V collagenase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
type: Class
subclass of: protein kinase inhibitor
subclass of: EC 2.7.11.* (protein-serine/threonine kinase) inhibitor
has_related_synonym: ATP:protein phosphotransferase (MAPKK-activated) inhibitor
has_related_synonym: ATP:protein phosphotransferase (MAPKK-activated) inhibitors
definition: An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of mitogen-activated protein kinase (EC 2.7.11.24).
has_alternative_id: CHEBI:75997
id: CHEBI:79091
has_related_synonym: Dp38 inhibitor
has_related_synonym: Dp38 inhibitors
has_related_synonym: EC 2.7.11.24 (mitogen-activated protein kinase) inhibitors
has_related_synonym: EC 2.7.11.24 inhibitor
has_related_synonym: EC 2.7.11.24 inhibitors
has_related_synonym: ERK inhibitor
has_related_synonym: ERK inhibitors
has_related_synonym: ERK1 inhibitor
has_related_synonym: ERK1 inhibitors
has_related_synonym: ERK2 inhibitor
has_related_synonym: ERK2 inhibitors
has_related_synonym: JNK inhibitor
has_related_synonym: JNK inhibitors
has_related_synonym: JNK3alpha1 inhibitor
has_related_synonym: JNK3alpha1 inhibitors
has_related_synonym: LeMPK3 inhibitor
has_related_synonym: LeMPK3 inhibitors
has_related_synonym: MAP kinase inhibitor
has_related_synonym: MAP kinase inhibitors
has_related_synonym: MAP-2 kinase inhibitor
has_related_synonym: MAP-2 kinase inhibitors
has_related_synonym: MAPK inhibitor
has_related_synonym: MAPK inhibitors
has_related_synonym: MBP kinase I inhibitor
has_related_synonym: MBP kinase I inhibitors
has_related_synonym: MBP kinase II inhibitor
has_related_synonym: MBP kinase II inhibitors
has_related_synonym: MEK inhibitor
has_related_synonym: MEK inhibitors
has_related_synonym: PMK-1 inhibitor
has_related_synonym: PMK-1 inhibitors
has_related_synonym: PMK-2 inhibitor
has_related_synonym: PMK-2 inhibitors
has_related_synonym: PMK-3 inhibitor
has_related_synonym: PMK-3 inhibitors
has_related_synonym: SAPK inhibitor
has_related_synonym: SAPK inhibitors
has_related_synonym: STK26 inhibitor
has_related_synonym: STK26 inhibitors
database_cross_reference: Wikipedia:MEK_inhibitor
database_cross_reference: Wikipedia:Mitogen-activated_protein_kinase
has_related_synonym: c-Jun N-terminal kinase inhibitor
has_related_synonym: c-Jun N-terminal kinase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: extracellular signal-regulated kinase inhibitor
has_related_synonym: extracellular signal-regulated kinase inhibitors
has_related_synonym: microtubule-associated protein 2 kinase inhibitor
has_related_synonym: microtubule-associated protein 2 kinase inhibitors
has_related_synonym: microtubule-associated protein kinase inhibitor
has_related_synonym: microtubule-associated protein kinase inhibitors
has_related_synonym: mitogen-activated protein kinase (EC 2.7.11.24) inhibitor
has_related_synonym: mitogen-activated protein kinase (EC 2.7.11.24) inhibitors
has_related_synonym: mitogen-activated protein kinase inhibitor
has_related_synonym: mitogen-activated protein kinase inhibitors
has_related_synonym: myelin basic protein kinase inhibitor
has_related_synonym: myelin basic protein kinase inhibitors
has_related_synonym: p38-2 inhibitor
has_related_synonym: p38-2 inhibitors
has_related_synonym: p38delta inhibitor
has_related_synonym: p38delta inhibitors
has_related_synonym: p42 mitogen-activated protein kinase inhibitor
has_related_synonym: p42 mitogen-activated protein kinase inhibitors
has_related_synonym: p42(mapk) inhibitor
has_related_synonym: p42(mapk) inhibitors
has_related_synonym: p44mpk inhibitor
has_related_synonym: p44mpk inhibitors
has_related_synonym: pp42 inhibitor
has_related_synonym: pp42 inhibitors
has_related_synonym: pp44(mapk) inhibitor
has_related_synonym: pp44(mapk) inhibitors
has_related_synonym: stress-activated protein kinase inhibitor

EC 1.11.2.* (oxidoreductase with H2O2 as acceptor, incorporating 1 O atom into product) inhibitor
type: Class
subclass of: EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitor
definition: An EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitor that interferes with the action of any such enzyme using H2O2 as acceptor and incorporating one oxygen atom of the H2O2 into the product (EC 1.11.2.*).
id: CHEBI:79092
has_related_synonym: EC 1.11.2.* (oxidoreductase with H2O2 as acceptor, incorporating 1 O atom into product) inhibitors
has_related_synonym: EC 1.11.2.* inhibitor
has_related_synonym: EC 1.11.2.* inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 1.11.2.2 (myeloperoxidase) inhibitor
type: Class
subclass of: EC 1.11.2.* (oxidoreductase with H2O2 as acceptor, incorporating 1 O atom into product) inhibitor
definition: An EC 1.11.2.* (oxidoreductase with H2O2 as acceptor, incorporating 1 O atom into product) inhibitor that interferes with the action of myeloperoxidase (EC 1.11.2.2).
id: CHEBI:79093
has_related_synonym: EC 1.11.2.2 (myeloperoxidase) inhibitors
has_related_synonym: EC 1.11.2.2 inhibitor
has_related_synonym: EC 1.11.2.2 inhibitors
has_related_synonym: MPO inhibitor
has_related_synonym: MPO inhibitors
database_cross_reference: Wikipedia:Myeloperoxidase
has_obo_namespace: chebi_ontology
has_related_synonym: chloride:hydrogen-peroxide oxidoreductase (hypochlorite-forming) inhibitor
has_related_synonym: chloride:hydrogen-peroxide oxidoreductase (hypochlorite-forming) inhibitors
has_related_synonym: myeloperoxidase (EC 1.11.2.2) inhibitor
has_related_synonym: myeloperoxidase (EC 1.11.2.2) inhibitors
has_related_synonym: myeloperoxidase inhibitor
has_related_synonym: myeloperoxidase inhibitors
has_related_synonym: verdoperoxidase inhibitor
has_related_synonym: verdoperoxidase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

flame retardant
type: Class
subclass of: application
definition: Any compound that is added to manufactured materials to inhibit, suppress, or delay the production of flames and so prevent the spread of fire.
id: CHEBI:79314
database_cross_reference: Wikipedia:Flame_retardant
has_obo_namespace: chebi_ontology
has_related_synonym: flame retardants
in_subset: 3 STAR
imported from: chebi.owl

paroxetine
type: Class
subclass of: molecular entity
has_exact_synonym: (3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine
has_related_synonym: (3S-trans)-3-((1,3-benzodioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine
charge: 0
monoisotopicmass: 329.14272
mass: 329.36540
definition: A benzodioxole that consists of piperidine bearing 1,3-benzodioxol-5-yloxy)methyl and 4-fluorophenyl substituents at positions 3 and 4 respectively; the (3S,4R)-diastereomer. Highly potent and selective 5-HT uptake inhibitor that binds with high affinity to the serotonin transporter (Ki = 0.05 nM). Ki values are 1.1, 350 and 1100 nM for inhibition of [3H]-5-HT, [3H]-l-NA and [3H]-DA uptake respectively. Displays minimal affinity for alpha1-, alpha2- or beta-adrenoceptors, 5-HT2A, 5-HT1A, D2 or H1 receptors at concentrations below 1000 nM, however displays weak affinity for muscarinic ACh receptors (Ki = 42 nM). Antidepressant and anxiolytic in vivo.
inchikey: AHOUBRCZNHFOSL-YOEHRIQHSA-N
formula: C19H20FNO3
database_cross_reference: CAS:61869-08-7
id: CHEBI:7936
database_cross_reference: DrugBank:DB00715
database_cross_reference: Drug_Central:2068
inchi: InChI=1S/C19H20FNO3/c20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-6-18-19(9-16)24-12-23-18/h1-6,9,14,17,21H,7-8,10-12H2/t14-,17-/m0/s1
database_cross_reference: KEGG:C07415
database_cross_reference: KEGG:D02362
database_cross_reference: LINCS:LSM-2843
database_cross_reference: PMID:11009210
database_cross_reference: PMID:11169163
database_cross_reference: PMID:11271409
database_cross_reference: PMID:11281965
database_cross_reference: PMID:11324355
database_cross_reference: PMID:11360029
database_cross_reference: PMID:11513198
database_cross_reference: PMID:11563413
database_cross_reference: PMID:11565622
database_cross_reference: PMID:11819027
database_cross_reference: PMID:11893234
database_cross_reference: PMID:11910269
database_cross_reference: PMID:12027788
database_cross_reference: PMID:12088162
database_cross_reference: PMID:12369443
database_cross_reference: PMID:12421645
database_cross_reference: PMID:12818234
database_cross_reference: PMID:12820211
database_cross_reference: PMID:12906023
database_cross_reference: PMID:12920419
database_cross_reference: PMID:14516531
database_cross_reference: PMID:14521492
database_cross_reference: PMID:14566196
database_cross_reference: PMID:14566200
database_cross_reference: PMID:14619895
database_cross_reference: PMID:14624192
database_cross_reference: PMID:14673053
database_cross_reference: PMID:14689334
database_cross_reference: PMID:14978354
database_cross_reference: PMID:15048901
database_cross_reference: PMID:15199661
database_cross_reference: PMID:15241233
database_cross_reference: PMID:15264994
database_cross_reference: PMID:15374134
database_cross_reference: PMID:15376524
database_cross_reference: PMID:15544025
database_cross_reference: PMID:15613191
database_cross_reference: PMID:15845695
database_cross_reference: PMID:15853570
database_cross_reference: PMID:15903129
database_cross_reference: PMID:15963219
database_cross_reference: PMID:15992089
database_cross_reference: PMID:16395417
database_cross_reference: PMID:16397315
database_cross_reference: PMID:16426087
database_cross_reference: PMID:16765127
database_cross_reference: PMID:16822276
database_cross_reference: PMID:16913391
database_cross_reference: PMID:17122538
database_cross_reference: PMID:17162096
database_cross_reference: PMID:17219219
database_cross_reference: PMID:17286545
database_cross_reference: PMID:17452166
database_cross_reference: PMID:17559097
database_cross_reference: PMID:17612590
database_cross_reference: PMID:17652957
database_cross_reference: PMID:17874333
database_cross_reference: PMID:18273418
database_cross_reference: PMID:18345955
database_cross_reference: PMID:18808757
database_cross_reference: PMID:18983224

glycerophosphoinositol synthesis inhibitor
type: Class
subclass of: pathway inhibitor
definition: A pathway inhibitor that disrupts the synthesis of glycerophosphoinositol
id: CHEBI:79386
has_related_synonym: GPI synthesis inhibitor
has_related_synonym: GPI synthesis inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: glycerophosphoinositol synthesis inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 6.1.1.2 (tryptophan--tRNA ligase) inhibitor
type: Class
subclass of: EC 6.1.1.* (ligases forming aminoacyl tRNA and related compounds) inhibitor
definition: An EC 6.1.1.* (ligases forming aminoacyl tRNA and related compounds) inhibitor that interferes with the action of any tryptophan--tRNA ligase (EC 6.1.1.2).
id: CHEBI:79392
has_related_synonym: EC 6.1.1.2 (tryptophan--tRNA ligase) inhibitors
has_related_synonym: EC 6.1.1.2 inhibitor
has_related_synonym: EC 6.1.1.2 inhibitors
has_related_synonym: L-tryptophan-tRNA(Trp) ligase (AMP-forming) inhibitor
has_related_synonym: L-tryptophan-tRNA(Trp) ligase (AMP-forming) inhibitors
has_related_synonym: L-tryptophan:tRNA(Trp) ligase (AMP-forming) inhibitor
has_related_synonym: L-tryptophan:tRNA(Trp) ligase (AMP-forming) inhibitors
has_related_synonym: TrpRS inhibitor
has_related_synonym: TrpRS inhibitors
database_cross_reference: Wikipedia:Tryptophan-tRNA_ligase
has_obo_namespace: chebi_ontology
has_related_synonym: tryptophan translase inhibitor
has_related_synonym: tryptophan translase inhibitors
has_related_synonym: tryptophan--tRNA ligase (EC 6.1.1.2) inhibitor
has_related_synonym: tryptophan--tRNA ligase (EC 6.1.1.2) inhibitors
has_related_synonym: tryptophanyl ribonucleic synthetase inhibitor
has_related_synonym: tryptophanyl ribonucleic synthetase inhibitors
has_related_synonym: tryptophanyl-tRNA synthase inhibitor
has_related_synonym: tryptophanyl-tRNA synthase inhibitors
has_related_synonym: tryptophanyl-tRNA synthetase inhibitor
has_related_synonym: tryptophanyl-tRNA synthetase inhibitors
has_related_synonym: tryptophanyl-transfer RNA synthetase inhibitor
has_related_synonym: tryptophanyl-transfer RNA synthetase inhibitors
has_related_synonym: tryptophanyl-transfer ribonucleate synthetase inhibitor
has_related_synonym: tryptophanyl-transfer ribonucleate synthetase inhibitors
has_related_synonym: tryptophanyl-transfer ribonucleic acid synthetase inhibitor
has_related_synonym: tryptophanyl-transfer ribonucleic acid synthetase inhibitors
has_related_synonym: tryptophanyl-transfer ribonucleic synthetase inhibitor
has_related_synonym: tryptophanyl-transfer ribonucleic synthetase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

phenacetin
type: Class
subclass of: molecular entity
charge: 0
has_related_synonym: 1-Acetamido-4-ethoxybenzene
monoisotopicmass: 179.09463
mass: 179.216
has_related_synonym: 4-Ethoxyacetanilide
definition: A member of the class of acetamides that is acetamide in which one of the hydrogens attached to the nitrogen is substituted by a 4-ethoxyphenyl group.
has_related_synonym: Acetophenetidin
has_related_synonym: Acetophenetidine
has_related_synonym: Acetophenetin
has_related_synonym: Acetphenetidin
has_related_synonym: Achrocidin
formula: C10H13NO2
smiles: C=1C=C(OCC)C=CC1NC(C)=O
database_cross_reference: CAS:62-44-2
id: CHEBI:8050
inchikey: CPJSUEIXXCENMM-UHFFFAOYSA-N
has_related_synonym: Codempiral
has_related_synonym: Commotional
has_related_synonym: Contradol
has_related_synonym: Contradouleur
database_cross_reference: DrugBank:DB03783
database_cross_reference: Drug_Central:2115
has_related_synonym: Fenacetina
inchi: InChI=1S/C10H13NO2/c1-3-13-10-6-4-9(5-7-10)11-8(2)12/h4-7H,3H2,1-2H3,(H,11,12)
database_cross_reference: KEGG:C07591
database_cross_reference: KEGG:D00569
database_cross_reference: LINCS:LSM-2851
has_exact_synonym: N-(4-ethoxyphenyl)acetamide
has_related_synonym: N-(4-ethoxyphenyl)acetamide
database_cross_reference: PDBeChem:N4E
database_cross_reference: PMID:24201458
database_cross_reference: PMID:24447449
database_cross_reference: Patent:US2887513
has_exact_synonym: Phenacetin
has_related_synonym: Phenacetine
has_related_synonym: Phenacetinum
database_cross_reference: Reaxys:1869238
database_cross_reference: Wikipedia:Phenacetin
has_obo_namespace: chebi_ontology
has_related_synonym: phenacetin
in_subset: 3 STAR
imported from: chebi.owl

phytochrome chromophore
type: Class
subclass of: chromophore
definition: A chromophore that is a linear tetrapyrrolic prosthetic group covalently attached to a large soluble protein phytochrome. Light absorption by the phytochrome chromophore triggers photoconversion between two spectrally distinct forms of the photoreceptor: Pr, the red light absorbing form, and Pfr, the far-red light absorbing form.
id: CHEBI:82632
database_cross_reference: PMID:2909515
has_obo_namespace: chebi_ontology
has_related_synonym: phytochrome chromophores
in_subset: 3 STAR
imported from: chebi.owl

animal growth promotant
type: Class
subclass of: agrochemical
id: CHEBI:82655
database_cross_reference: PMID:22444918
database_cross_reference: PMID:2745641
database_cross_reference: PMID:6226938
definition: Substances that are administered to farmed animals to improve productivity by promoting weight gain, increasing muscle mass, limiting fat deposition, reducing feed consumption, and reducing waste production.
has_related_synonym: animal growth promotants
has_related_synonym: animal growth promoter
has_related_synonym: animal growth promoters
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
type: Class
subclass of: EC 2.7.11.* (protein-serine/threonine kinase) inhibitor
has_related_synonym: ATP:cyclin phosphotransferase inhibitor
has_related_synonym: ATP:cyclin phosphotransferase inhibitors
definition: An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of cyclin-dependent kinase (EC 2.7.11.22).
has_related_synonym: Bur1 Cdk inhibitor
has_related_synonym: Bur1 Cdk inhibitors
has_related_synonym: Bur1 inhibitor
has_related_synonym: Bur1 inhibitors
has_related_synonym: CDK inhibitor
has_related_synonym: CDK inhibitors
id: CHEBI:82665
has_related_synonym: Cak1 inhibitor
has_related_synonym: Cak1 inhibitors
has_related_synonym: Cak1p inhibitor
has_related_synonym: Cak1p inhibitors
has_related_synonym: Cdc28p inhibitor
has_related_synonym: Cdc28p inhibitors
has_related_synonym: Cdk-activating protein kinase inhibitors
has_related_synonym: Cdk1 inhibitor
has_related_synonym: Cdk1 inhibitors
has_related_synonym: Cdk19 inhibitor
has_related_synonym: Cdk19 inhibitors
has_related_synonym: Cdk2 inhibitor
has_related_synonym: Cdk2 inhibitors
has_related_synonym: Cdk3 inhibitor
has_related_synonym: Cdk3 inhibitors
has_related_synonym: Cdk4 inhibitor
has_related_synonym: Cdk4 inhibitors
has_related_synonym: Cdk5 inhibitor
has_related_synonym: Cdk5 inhibitors
has_related_synonym: Cdk6 inhibitor
has_related_synonym: Cdk6 inhibitors
has_related_synonym: Cdk7 inhibitor
has_related_synonym: Cdk7 inhibitors
has_related_synonym: Cdk8 inhibitor
has_related_synonym: Cdk8 inhibitors
has_related_synonym: Cdk9 inhibitor
has_related_synonym: Cdk9 inhibitors
has_related_synonym: D-type cyclin kinase inhibitor
has_related_synonym: D-type cyclin kinase inhibitors
has_related_synonym: EC 2.7.11.22 (cyclin-dependent kinase) inhibitors
has_related_synonym: EC 2.7.11.22 inhibitor
has_related_synonym: EC 2.7.11.22 inhibitors
has_related_synonym: PCTAIRE-1 inhibitor
has_related_synonym: PCTAIRE-1 inhibitors
has_related_synonym: STK25 inhibitor
has_related_synonym: STK25 inhibitors
has_related_synonym: cdc2 inhibitor
has_related_synonym: cdc2 inhibitors
has_related_synonym: cdc2 kinase inhibitor
has_related_synonym: cdc2 kinase inhibitors
has_related_synonym: cdk-activating kinase inhibitor
has_related_synonym: cdk-activating kinase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: cyclin A-activated cdc2 inhibitor
has_related_synonym: cyclin A-activated cdc2 inhibitors
has_related_synonym: cyclin A-activated cdk2 inhibitor
has_related_synonym: cyclin A-activated cdk2 inhibitors
has_related_synonym: cyclin D-cdk6 kinase inhibitor
has_related_synonym: cyclin D-cdk6 kinase inhibitors
has_related_synonym: cyclin D-dependent kinase inhibitor
has_related_synonym: cyclin D-dependent kinase inhibitors
has_related_synonym: cyclin E kinase inhibitor
has_related_synonym: cyclin E kinase inhibitors
has_related_synonym: cyclin-A associated kinase inhibitor
has_related_synonym: cyclin-A associated kinase inhibitors
has_related_synonym: cyclin-dependent kinase 6 inhibitor
has_related_synonym: cyclin-dependent kinase 6 inhibitors
has_related_synonym: cyclin-dependent kinase inhibitor
has_related_synonym: cyclin-dependent kinase inhibitors
has_related_synonym: cyclin-dependent kinase-2 inhibitor
has_related_synonym: cyclin-dependent kinase-2 inhibitors
has_related_synonym: cyclin-dependent kinase-4 inhibitor
has_related_synonym: cyclin-dependent kinase-4 inhibitors
has_related_synonym: cyclin-dependent protein kinase activating kinase inhibitor
has_related_synonym: cyclin-dependent protein kinase activating kinase inhibitors
has_related_synonym: cyk inhibitor
has_related_synonym: cyk inhibitors

EC 6.1.1.12 (aspartate--tRNA ligase) inhibitor
type: Class
subclass of: EC 6.1.1.* (ligases forming aminoacyl tRNA and related compounds) inhibitor
definition: An EC 6.1.1.* (ligases forming aminoacyl tRNA and related compounds) inhibitor that specifically inhibits the action of aspartate--tRNA ligase (EC 6.1.1.12).
id: CHEBI:82756
has_related_synonym: EC 6.1.1.12 (aspartate--tRNA ligase) inhibitors
has_related_synonym: EC 6.1.1.12 inhibitor
has_related_synonym: EC 6.1.1.12 inhibitors
has_related_synonym: L-aspartate:tRNA(Asp) ligase (AMP-forming) inhibitor
has_related_synonym: L-aspartate:tRNA(Asp) ligase (AMP-forming) inhibitors
has_related_synonym: aspartic acid translase inhibitor
has_related_synonym: aspartic acid translase inhibitors
has_related_synonym: aspartyl ribonucleate synthetase inhibitor
has_related_synonym: aspartyl ribonucleate synthetase inhibitors
has_related_synonym: aspartyl ribonucleic synthetase inhibitor
has_related_synonym: aspartyl ribonucleic synthetase inhibitors
has_related_synonym: aspartyl-tRNA synthetase inhibitors
has_related_synonym: aspartyl-transfer RNA synthetase inhibitor
has_related_synonym: aspartyl-transfer RNA synthetase inhibitors
has_related_synonym: aspartyl-transfer ribonucleic acid synthetase inhibitor
has_related_synonym: aspartyl-transfer ribonucleic acid synthetase inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.22.53 (calpain-2) inhibitor
type: Class
subclass of: calpain inhibitor
definition: A calpain inhibitor that interferes with the action of calpain-2 (EC 3.4.22.53).
id: CHEBI:82821
has_related_synonym: EC 3.4.22.53 (calpain-2) inhibitors
has_related_synonym: EC 3.4.22.53 inhibitor
has_related_synonym: EC 3.4.22.53 inhibitors
database_cross_reference: Wikipedia:Calpain-2
has_related_synonym: calcium-activated neutral protease II inhibitor
has_related_synonym: calcium-activated neutral protease II inhibitors
has_related_synonym: calpain-2 (EC 3.4.22.53) inhibitor
has_related_synonym: calpain-2 (EC 3.4.22.53) inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: m-calpain inhibitor
has_related_synonym: m-calpain inhibitors
has_related_synonym: milli-calpain inhibitor
has_related_synonym: milli-calpain inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.22.54 (calpain-3) inhibitor
type: Class
subclass of: calpain inhibitor
definition: An EC 3.4.22.* (cysteine endopeptidase) inhibitor that interferes with the action of calpain-3 (EC 3.4.22.54).
has_related_synonym: CANP 3 inhibitor
has_related_synonym: CANP 3 inhibitors
has_related_synonym: CAPN3 inhibitor
has_related_synonym: CAPN3 inhibitors
id: CHEBI:82823
has_related_synonym: EC 3.4.22.54 (calpain-3) inhibitors
has_related_synonym: EC 3.4.22.54 inhibitor
has_related_synonym: EC 3.4.22.54 inhibitors
database_cross_reference: Wikipedia:Calpain-3
has_related_synonym: calcium-activated neutral proteinase 3 inhibitor
has_related_synonym: calcium-activated neutral proteinase 3 inhibitors
has_related_synonym: calpain 3 inhibitor
has_related_synonym: calpain 3 inhibitors
has_related_synonym: calpain L3 inhibitor
has_related_synonym: calpain L3 inhibitors
has_related_synonym: calpain p94 inhibitor
has_related_synonym: calpain p94 inhibitors
has_related_synonym: calpain-3 (EC 3.4.22.54) inhibitor
has_related_synonym: calpain-3 (EC 3.4.22.54) inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: muscle calpain inhibitor
has_related_synonym: muscle calpain inhibitors
has_related_synonym: muscle-specific calcium-activated neutral protease 3 inhibitor
has_related_synonym: muscle-specific calcium-activated neutral protease 3 inhibitors
has_related_synonym: p94 inhibitor
has_related_synonym: p94 inhibitors
in_subset: 3 STAR
imported from: chebi.owl

calpain inhibitor
type: Class
subclass of: cysteine protease inhibitor
subclass of: EC 3.4.22.* (cysteine endopeptidase) inhibitor
definition: An EC 3.4.22.* (cysteine endopeptidase) inhibitor that interferes with the action of any calpain.
id: CHEBI:82824
database_cross_reference: PMID:22253611
database_cross_reference: PMID:22863139
database_cross_reference: Wikipedia:Calpain
has_related_synonym: calpain inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

glucocorticoid receptor antagonist
type: Class
subclass of: antagonist
definition: An antagonist that binds to and deactivates glucocorticoid receptors.
id: CHEBI:82891
has_obo_namespace: chebi_ontology
has_related_synonym: glucocorticoid receptor antagonists
in_subset: 3 STAR
imported from: chebi.owl

gut flora metabolite
type: Class
subclass of: metabolite
id: CHEBI:82933
definition: Metabolites produced by the gut microbiota or microorganisms (e.g. bacteria and fungi) that live in the digestive tracts of animals.
database_cross_reference: Wikipedia:Gut_flora
has_obo_namespace: chebi_ontology
has_related_synonym: gut flora metabolites
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.24.11 (neprilysin) inhibitor
type: Class
subclass of: EC 3.4.24.* (metalloendopeptidase) inhibitor
definition: An EC 3.4.24.* (metalloendopeptidase) inhibitor that interferes with the action of neprilysin (EC 3.4.24.11).
has_related_synonym: CALLA (common acute lymphoblastic leukemia-associated) antigens inhibitor
has_related_synonym: CALLA (common acute lymphoblastic leukemia-associated) antigens inhibitors
has_related_synonym: CALLA antigen inhibitor
has_related_synonym: CALLA antigen inhibitors
has_related_synonym: CALLA glycoprotein inhibitor
has_related_synonym: CALLA glycoprotein inhibitors
has_related_synonym: CALLA glycoproteins inhibitor
has_related_synonym: CALLA glycoproteins inhibitors
has_related_synonym: CALLA inhibitor
has_related_synonym: CALLA inhibitors
has_related_synonym: CD10 inhibitor
has_related_synonym: CD10 inhibitors
id: CHEBI:82973
has_related_synonym: EC 3.4.24.11 (neprilysin) inhibitors
has_related_synonym: EC 3.4.24.11 inhibitor
has_related_synonym: EC 3.4.24.11 inhibitors
has_related_synonym: NEP inhibitor
has_related_synonym: NEP inhibitors
database_cross_reference: Wikipedia:Neprilysin
has_related_synonym: acute lymphoblastic leukemia antigen inhibitor
has_related_synonym: acute lymphoblastic leukemia antigen inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: common acute lymphoblastic leukemia antigen inhibitor
has_related_synonym: common acute lymphoblastic leukemia antigen inhibitors
has_related_synonym: common acute lymphoblastic leukemia-associated antigens inhibitor
has_related_synonym: common acute lymphoblastic leukemia-associated antigens inhibitors
has_related_synonym: endopeptidase 24.11 inhibitor
has_related_synonym: endopeptidase 24.11 inhibitors
has_related_synonym: endopeptidase inhibitor
has_related_synonym: endopeptidase inhibitors
has_related_synonym: endopeptidase-2 inhibitor
has_related_synonym: endopeptidase-2 inhibitors
has_related_synonym: enkephalinase inhibitor
has_related_synonym: enkephalinase inhibitors
has_related_synonym: kidney-brush-border neutral endopeptidase inhibitor
has_related_synonym: kidney-brush-border neutral endopeptidase inhibitors
has_related_synonym: kidney-brush-border neutral peptidase inhibitor
has_related_synonym: kidney-brush-border neutral peptidase inhibitors
has_related_synonym: kidney-brush-border neutral proteinase inhibitor
has_related_synonym: kidney-brush-border neutral proteinase inhibitors
has_related_synonym: membrane metalloendopeptidase inhibitor
has_related_synonym: membrane metalloendopeptidase inhibitors
has_related_synonym: neprilysin (EC 3.4.24.11) inhibitor
has_related_synonym: neprilysin (EC 3.4.24.11) inhibitors
has_related_synonym: neprilysin inhibitor
has_related_synonym: neprilysin inhibitors
has_related_synonym: neutral endopeptidase 24.11 inhibitor
has_related_synonym: neutral endopeptidase 24.11 inhibitors
has_related_synonym: neutral endopeptidase inhibitor
has_related_synonym: neutral endopeptidase inhibitors
has_related_synonym: neutral metallendopeptidase inhibitor
has_related_synonym: neutral metallendopeptidase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.24.71 (endothelin-converting enzyme 1) inhibitor
type: Class
subclass of: EC 3.4.24.* (metalloendopeptidase) inhibitor
definition: An EC 3.4.24.* (metalloendopeptidase) inhibitor that interferes with the action of endothelin-converting enzyme 1 (EC 3.4.24.71).
id: CHEBI:82974
has_related_synonym: EC 3.4.24.71 (endothelin-converting enzyme 1) inhibitors
has_related_synonym: EC 3.4.24.71 inhibitor
has_related_synonym: EC 3.4.24.71 inhibitors
has_related_synonym: ECE-1 inhibitor
has_related_synonym: ECE-1 inhibitors
database_cross_reference: Wikipedia:Endothelin-converting_enzyme_1
has_obo_namespace: chebi_ontology
has_related_synonym: endothelin-converting enzyme 1 (EC 3.4.24.71) inhibitor
has_related_synonym: endothelin-converting enzyme 1 (EC 3.4.24.71) inhibitors
has_related_synonym: endothelin-converting enzyme 1 inhibitor
has_related_synonym: endothelin-converting enzyme 1 inhibitors
has_related_synonym: endothelin-converting enzyme inhibitor
has_related_synonym: endothelin-converting enzyme inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 4.1.2.27 (sphinganine-1-phosphate aldolase) inhibitor
type: Class
subclass of: EC 4.1.2.* (aldehyde-lyase) inhibitor
definition: An EC 4.1.2.* (aldehyde-lyase) inhibitor that interferes with the action of sphinganine-1-phosphate aldolase (EC 4.1.2.27).
id: CHEBI:83034
has_related_synonym: EC 4.1.2.27 (sphinganine-1-phosphate aldolase) inhibitors
has_related_synonym: EC 4.1.2.27 inhibitor
has_related_synonym: EC 4.1.2.27 inhibitors
has_related_synonym: S1P lyase inhibitor
has_related_synonym: S1P lyase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: dihydrosphingosine 1-phosphate aldolase inhibitor
has_related_synonym: dihydrosphingosine 1-phosphate aldolase inhibitors
has_related_synonym: sphinganine-1-phosphate alkanal-lyase inhibitor
has_related_synonym: sphinganine-1-phosphate alkanal-lyase inhibitors
has_related_synonym: sphinganine-1-phosphate lyase inhibitor
has_related_synonym: sphinganine-1-phosphate lyase inhibitors
has_related_synonym: sphinganine-1-phosphate palmitaldehyde-lyase (phosphoethanolamine-forming) inhibitor
has_related_synonym: sphinganine-1-phosphate palmitaldehyde-lyase (phosphoethanolamine-forming) inhibitors
has_related_synonym: sphinganine-1-phosphate palmitaldehyde-lyase inhibitor
has_related_synonym: sphinganine-1-phosphate palmitaldehyde-lyase inhibitors
has_related_synonym: sphingosine-1-phosphate aldolase inhibitor
has_related_synonym: sphingosine-1-phosphate aldolase inhibitors
has_related_synonym: sphingosine-1-phosphate lyase inhibitor
has_related_synonym: sphingosine-1-phosphate lyase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 4.1.2.* (aldehyde-lyase) inhibitor
type: Class
subclass of: EC 4.1.1.* (carboxy-lyase) inhibitor
definition: An EC 4.1.* (C-C lyase) inhibitor that interferes with the action of any aldehyde-lyase (EC 4.1.2.*).
id: CHEBI:83035
has_related_synonym: EC 4.1.2.* (aldehyde-lyase) inhibitors
has_related_synonym: EC 4.1.2.* (aldehyde-lyases) inhibitor
has_related_synonym: EC 4.1.2.* (aldehyde-lyases) inhibitors
has_related_synonym: EC 4.1.2.* inhibitor
has_related_synonym: EC 4.1.2.* inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

Daphnia galeata metabolite
type: Class
subclass of: Daphnia metabolite
definition: A Daphnia metabolite produced by the species Daphnia galeata.
id: CHEBI:83038
has_related_synonym: Daphnia galeata metabolites
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

crustacean metabolite
type: Class
subclass of: animal metabolite
definition: An animal metabolite produced by arthropods such as crabs, lobsters, crayfish, shrimps and krill.
id: CHEBI:83039
has_obo_namespace: chebi_ontology
has_related_synonym: crustacean metabolites
in_subset: 3 STAR
imported from: chebi.owl

Daphnia magna metabolite
type: Class
subclass of: Daphnia metabolite
definition: A Daphnia metabolite produced by the species Daphnia magna.
id: CHEBI:83056
has_related_synonym: Daphnia magna metabolites
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

Daphnia metabolite
type: Class
subclass of: crustacean metabolite
definition: A crustacean metabolite produced by the genus of small planktonic arthropods, Daphnia
id: CHEBI:83057
has_related_synonym: Daphnia metabolites
database_cross_reference: Wikipedia:Daphnia
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor
type: Class
subclass of: EC 1.3.5.* (oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor) inhibitor
definition: An EC 1.3.5.* (oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor) inhibitor that interferes with the action of succinate dehydrogenase (quinone), EC 1.3.5.1.
id: CHEBI:83072
has_related_synonym: EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitors
has_related_synonym: EC 1.3.5.1 inhibitor
has_related_synonym: EC 1.3.5.1 inhibitors
has_related_synonym: SDH inhibitor
has_related_synonym: SDH inhibitors
database_cross_reference: Wikipedia:Succinate_dehydrogenase
has_obo_namespace: chebi_ontology
has_related_synonym: complex II inhibitor
has_related_synonym: complex II inhibitors
has_related_synonym: succinate dehydrogenase (ubiquinone) inhibitor
has_related_synonym: succinate dehydrogenase (ubiquinone) inhibitors
has_related_synonym: succinate dehydrogenase complex inhibitor
has_related_synonym: succinate dehydrogenase complex inhibitors
has_related_synonym: succinate dehydrogenase inhibitor
has_related_synonym: succinate dehydrogenase inhibitors
has_related_synonym: succinate:quinone oxidoreductase inhibitor
has_related_synonym: succinate:quinone oxidoreductase inhibitors
has_related_synonym: succinate:ubiquinone oxidoreductase inhibitor
has_related_synonym: succinate:ubiquinone oxidoreductase inhibitors
has_related_synonym: succinic dehydrogenase inhibitor
has_related_synonym: succinic dehydrogenase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

kairomone
type: Class
subclass of: semiochemical
definition: A semiochemical used for inter-species chemical communication in a way that benefits an individual of another species that receives the chemical signal.
id: CHEBI:83074
database_cross_reference: Wikipedia:Kairomone
has_obo_namespace: chebi_ontology
has_related_synonym: kairomones
in_subset: 3 STAR
imported from: chebi.owl

Daphnia pulex metabolite
type: Class
subclass of: Daphnia metabolite
definition: A Daphnia metabolite produced by the species Daphnia pulex.
id: CHEBI:83075
has_related_synonym: Daphnia pulex metabolites
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

Daphnia tenebrosa metabolite
type: Class
subclass of: Daphnia metabolite
definition: A Daphnia metabolite produced by the species Daphnia tenebrosa.
id: CHEBI:83146
has_related_synonym: Daphnia tenebrosa metabolites
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 6.2.1.* (acid-thiol ligase) inhibitor
type: Class
subclass of: EC 6.2.* (C-S bond-forming ligase) inhibitor
definition: An EC 6.2.* (C-S bond-forming ligase) inhibitor that interferes with the action of an acid-thiol ligase inhibitor (EC 6.2.1.*).
id: CHEBI:83156
has_related_synonym: EC 6.2.1.* (acid-thiol ligase) inhibitors
has_related_synonym: EC 6.2.1.* (acid-thiol ligases) inhibitor
has_related_synonym: EC 6.2.1.* (acid-thiol ligases) inhibitors
has_related_synonym: EC 6.2.1.* inhibitor
has_related_synonym: EC 6.2.1.* inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitor
type: Class
subclass of: EC 6.2.1.* (acid-thiol ligase) inhibitor
has_related_synonym: ACS3 inhibitor
has_related_synonym: ACS3 inhibitors
definition: An EC 6.2.1.* (acid-thiol ligase) inhibitor that interferes with the action of a long-chain-fatty-acid--CoA ligase (EC 6.2.1.3).
id: CHEBI:83157
has_related_synonym: EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitors
has_related_synonym: EC 6.2.1.3 inhibitor
has_related_synonym: EC 6.2.1.3 inhibitors
has_related_synonym: FAA1 inhibitor
has_related_synonym: FAA1 inhibitors
has_related_synonym: LCFA synthetase inhibitor
has_related_synonym: LCFA synthetase inhibitors
database_cross_reference: Wikipedia:Long-chain-fatty-acid-CoA_ligase
has_related_synonym: acyl coenzyme A synthetase inhibitor
has_related_synonym: acyl coenzyme A synthetase inhibitors
has_related_synonym: acyl-CoA ligase inhibitor
has_related_synonym: acyl-CoA ligase inhibitors
has_related_synonym: acyl-CoA synthetase inhibitor
has_related_synonym: acyl-CoA synthetase inhibitors
has_related_synonym: acyl-activating enzyme inhibitor
has_related_synonym: acyl-activating enzyme inhibitors
has_related_synonym: acyl-coenzyme A ligase inhibitor
has_related_synonym: acyl-coenzyme A ligase inhibitors
has_related_synonym: arachidonyl-CoA synthetase inhibitor
has_related_synonym: arachidonyl-CoA synthetase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: fatty acid CoA ligase inhibitor
has_related_synonym: fatty acid CoA ligase inhibitors
has_related_synonym: fatty acid elongase inhibitor
has_related_synonym: fatty acid elongase inhibitors
has_related_synonym: fatty acid thiokinase (long chain) inhibitor
has_related_synonym: fatty acid thiokinase (long chain) inhibitors
has_related_synonym: fatty acyl-coenzyme A synthetase inhibitor
has_related_synonym: fatty acyl-coenzyme A synthetase inhibitors
has_related_synonym: lignoceroyl-CoA synthase inhibitor
has_related_synonym: lignoceroyl-CoA synthase inhibitors
has_related_synonym: long chain fatty acyl-CoA synthetase inhibitor
has_related_synonym: long chain fatty acyl-CoA synthetase inhibitors
has_related_synonym: long-chain acyl CoA synthetase inhibitor
has_related_synonym: long-chain acyl CoA synthetase inhibitors
has_related_synonym: long-chain acyl-CoA synthetase I inhibitor
has_related_synonym: long-chain acyl-CoA synthetase I inhibitors
has_related_synonym: long-chain acyl-CoA synthetase II inhibitor
has_related_synonym: long-chain acyl-CoA synthetase II inhibitors
has_related_synonym: long-chain acyl-coenzyme A synthetase inhibitor
has_related_synonym: long-chain acyl-coenzyme A synthetase inhibitors
has_related_synonym: long-chain fatty acid:CoA ligase (AMP-forming) inhibitor
has_related_synonym: long-chain fatty acid:CoA ligase (AMP-forming) inhibitors
has_related_synonym: long-chain fatty acyl coenzyme A synthetase inhibitor
has_related_synonym: long-chain fatty acyl coenzyme A synthetase inhibitors
has_related_synonym: oleoyl-CoA synthetase inhibitor
has_related_synonym: oleoyl-CoA synthetase inhibitors
has_related_synonym: palmitoyl coenzyme A synthetase inhibitor
has_related_synonym: palmitoyl coenzyme A synthetase inhibitors
has_related_synonym: palmitoyl-CoA ligase inhibitor
has_related_synonym: palmitoyl-CoA ligase inhibitors
has_related_synonym: palmitoyl-CoA synthase inhibitor
has_related_synonym: palmitoyl-CoA synthase inhibitors
has_related_synonym: pristanoyl-CoA synthetase inhibitor
has_related_synonym: pristanoyl-CoA synthetase inhibitors
has_related_synonym: stearoyl-CoA synthetase inhibitor
has_related_synonym: stearoyl-CoA synthetase inhibitors
has_related_synonym: thiokinase inhibitor
has_related_synonym: thiokinase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

orexin receptor antagonist
type: Class
subclass of: antagonist
definition: An antagonist that binds to and deactivates orexin receptors.
id: CHEBI:83296
database_cross_reference: Wikipedia:Orexin_antagonist
has_obo_namespace: chebi_ontology
has_related_synonym: orexin receptor antagonists
in_subset: 3 STAR
imported from: chebi.owl

protease-activated receptor-1 antagonist
type: Class
subclass of: G-protein-coupled receptor antagonist
definition: An antagonist at the protease-activated receptor-1.
id: CHEBI:83313
has_related_synonym: PAR-1 antagonist
has_related_synonym: PAR-1 antagonists
has_related_synonym: PAR-1 receptor antagonist
has_related_synonym: PAR-1 receptor antagonists
has_related_synonym: PAR1 antagonist
has_related_synonym: PAR1 antagonists
database_cross_reference: PMID:20655904
database_cross_reference: PMID:25777282
database_cross_reference: PMID:35349275
database_cross_reference: Wikipedia:Coagulation_factor_II_receptor
has_obo_namespace: chebi_ontology
has_related_synonym: coagulation factor II (thrombin) receptor antagonist
has_related_synonym: coagulation factor II (thrombin) receptor antagonists
has_related_synonym: coagulation factor II receptor antagonist
has_related_synonym: coagulation factor II receptor antagonists
has_related_synonym: coagulation factor II thrombin receptor antagonist
has_related_synonym: coagulation factor II thrombin receptor antagonists
has_related_synonym: protease activated receptor 1 antagonist
has_related_synonym: protease activated receptor 1 antagonists
has_related_synonym: protease-activated receptor 1 antagonist
has_related_synonym: protease-activated receptor 1 antagonists
has_related_synonym: protease-activated receptor-1 antagonists
has_related_synonym: proteinase-activated receptor 1 antagonist
has_related_synonym: proteinase-activated receptor 1 antagonists
in_subset: 3 STAR
imported from: chebi.owl

EC 1.14.13.72 (methylsterol monooxygenase) inhibitor
type: Class
subclass of: EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor
has_related_synonym: 4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,NAD(P)H:oxygen oxidoreductase (hydroxylating) inhibitor
has_related_synonym: 4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,NAD(P)H:oxygen oxidoreductase (hydroxylating) inhibitors
has_related_synonym: 4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,hydrogen-donor:oxygen oxidoreductase (hydroxylating) inhibitor
has_related_synonym: 4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,hydrogen-donor:oxygen oxidoreductase (hydroxylating) inhibitors
has_related_synonym: 4-methylsterol oxidase inhibitor
has_related_synonym: 4-methylsterol oxidase inhibitors
definition: An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of methylsterol monooxygenase (EC 1.14.13.72).
id: CHEBI:83316
has_related_synonym: EC 1.14.13.72 (ethylsterol monooxygenase) inhibitors
has_related_synonym: EC 1.14.13.72 inhibitor
has_related_synonym: EC 1.14.13.72 inhibitors
database_cross_reference: Wikipedia:Methylsterol_monooxygenase
has_obo_namespace: chebi_ontology
has_related_synonym: methylsterol hydroxylase inhibitor
has_related_synonym: methylsterol hydroxylase inhibitors
has_related_synonym: methylsterol monooxygenase (EC 1.14.13.72) inhibitor
has_related_synonym: methylsterol monooxygenase (EC 1.14.13.72) inhibitors
has_related_synonym: methylsterol monooxygenase inhibitor
has_related_synonym: methylsterol monooxygenase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

sterol biosynthesis inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
definition: Any compound that inhibits the biosynthesis of any sterol.
id: CHEBI:83317
has_obo_namespace: chebi_ontology
has_related_synonym: sterol biosynthesis inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.3.1.70 (Delta(14)-sterol reductase) inhibitor
type: Class
subclass of: EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor
has_related_synonym: 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol:NADP(+) Delta(14)-oxidoreductase inhibitor
has_related_synonym: 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol:NADP(+) Delta(14)-oxidoreductase inhibitors
definition: An EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of Delta(14)-sterol reductase (EC 1.3.1.70).
has_related_synonym: C-14 sterol reductase inhibitor
has_related_synonym: C-14 sterol reductase inhibitors
id: CHEBI:83319
has_related_synonym: Delta(14)-sterol reductase (EC 1.3.1.70) inhibitor
has_related_synonym: Delta(14)-sterol reductase (EC 1.3.1.70) inhibitors
has_related_synonym: Delta(14)-sterol reductase inhibitor
has_related_synonym: Delta(14)-sterol reductase inhibitors
has_related_synonym: EC 1.3.1.70 (Delta(14)-sterol reductase) inhibitors
has_related_synonym: EC 1.3.1.70 inhibitor
has_related_synonym: EC 1.3.1.70 inhibitors
database_cross_reference: Wikipedia:Delta14-sterol_reductase
has_obo_namespace: chebi_ontology
has_related_synonym: sterol C14-reductase inhibitor
has_related_synonym: sterol C14-reductase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

marine xenobiotic metabolite
type: Class
subclass of: xenobiotic metabolite
subclass of: marine metabolite
definition: Any metabolite produced by metabolism of a xenobiotic compound in marine macro- and microorganisms.
id: CHEBI:83399
has_obo_namespace: chebi_ontology
has_related_synonym: marine xenobiotic metabolites
in_subset: 3 STAR
imported from: chebi.owl

steatosis inducing agent
type: Class
subclass of: biochemical role
definition: Any agent capable of inducing steatosis, a pathological condition characterised by accumulation or abnormal retention of fats within a cell.
id: CHEBI:83609
database_cross_reference: Wikipedia:Steatosis
has_obo_namespace: chebi_ontology
has_related_synonym: steatosis inducing agents
has_related_synonym: steatosis inducing drug
has_related_synonym: steatosis inducing drugs
in_subset: 3 STAR
imported from: chebi.owl

hepatic steatosis inducing agent
type: Class
subclass of: hepatotoxic agent
subclass of: steatosis inducing agent
definition: Any hepatotoxic agent capable of inducing liver steatosis or fatty liver disease.
id: CHEBI:83612
has_obo_namespace: chebi_ontology
has_related_synonym: hepatic steatosis inducing agents
has_related_synonym: hepatic steatosis inducing drug
has_related_synonym: hepatic steatosis inducing drugs
in_subset: 3 STAR
imported from: chebi.owl

sterol demethylation inhibitor
type: Class
subclass of: antifungal agent
subclass of: sterol biosynthesis inhibitor
definition: A sterol biosynthesis inhibitor that acts by inhibiting the C14 demethylation step within fungal steroid biosynthesis.
id: CHEBI:83734
has_obo_namespace: chebi_ontology
has_related_synonym: sterol demethylation inhibitors
in_subset: 3 STAR
imported from: chebi.owl

phospholipid biosynthesis inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
definition: Any compound that inhibits the biosynthesis of any phospholipid.
id: CHEBI:83741
has_obo_namespace: chebi_ontology
has_related_synonym: phospholipid biosynthesis inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.4.1.231 [alpha,alpha-trehalose phosphorylase (configuration-retaining)] inhibitor
type: Class
subclass of: EC 2.4.1.* (hexosyltransferase) inhibitor
definition: An EC 2.4.1.* (hexosyltransferase) inhibitor that interferes with the action of alpha,alpha-trehalose phosphorylase (configuration-retaining) (EC 2.4.1.231).
id: CHEBI:83757
has_related_synonym: EC 2.4.1.231 [alpha,alpha-trehalose phosphorylase (configuration-retaining)] inhibitors
has_related_synonym: EC 2.4.1.231 inhibitor
has_related_synonym: EC 2.4.1.231 inhibitors
database_cross_reference: Wikipedia:Alpha,alpha-trehalose_phosphorylase_(configuration-retaining)
has_related_synonym: alpha,alpha-trehalose phosphorylase (configuration-retaining) (EC 2.4.1.231) inhibitor
has_related_synonym: alpha,alpha-trehalose phosphorylase (configuration-retaining) (EC 2.4.1.231) inhibitors
has_related_synonym: alpha,alpha-trehalose phosphorylase (configuration-retaining) inhibitor
has_related_synonym: alpha,alpha-trehalose phosphorylase (configuration-retaining) inhibitors
has_related_synonym: alpha,alpha-trehalose:phosphate alpha-D-glucosyltransferase inhibitor
has_related_synonym: alpha,alpha-trehalose:phosphate alpha-D-glucosyltransferase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: trehalose phosphorylase inhibitor
has_related_synonym: trehalose phosphorylase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.4.1.64 (alpha,alpha-trehalose phosphorylase) inhibitor
type: Class
subclass of: EC 2.4.1.* (hexosyltransferase) inhibitor
definition: An EC 2.4.1.* (hexosyltransferase) inhibitor that interferes with the action of alpha,alpha-trehalose phosphorylase (EC 2.4.1.64).
id: CHEBI:83760
has_related_synonym: EC 2.4.1.64 (alpha,alpha-trehalose phosphorylase) inhibitors
has_related_synonym: EC 2.4.1.64 inhibitor
has_related_synonym: EC 2.4.1.64 inhibitors
database_cross_reference: Wikipedia:Alpha,alpha-trehalose_phosphorylase
has_related_synonym: alpha,alpha-trehalose phosphorylase (EC 2.4.1.64) inhibitor
has_related_synonym: alpha,alpha-trehalose phosphorylase (EC 2.4.1.64) inhibitors
has_related_synonym: alpha,alpha-trehalose phosphorylase inhibitor
has_related_synonym: alpha,alpha-trehalose phosphorylase inhibitors
has_related_synonym: alpha,alpha-trehalose:phosphate beta-D-glucosyltransferase inhibitor
has_related_synonym: alpha,alpha-trehalose:phosphate beta-D-glucosyltransferase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: trehalose phosphorylase inhibitor
has_related_synonym: trehalose phosphorylase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.2.1.28 (alpha,alpha-trehalase) inhibitor
type: Class
subclass of: EC 2.4.1.* (hexosyltransferase) inhibitor
definition: An EC 2.4.1.* (hexosyltransferase) inhibitor that interferes with the action of alpha,alpha-trehalase (EC 2.4.1.28).
id: CHEBI:83762
has_related_synonym: EC 3.2.1.28 (alpha,alpha-trehalase) inhibitors
has_related_synonym: EC 3.2.1.28 inhibitor
has_related_synonym: EC 3.2.1.28 inhibitors
database_cross_reference: Wikipedia:Alpha,alpha-trehalase
has_related_synonym: alpha,alpha-trehalase (EC 3.2.1.28) inhibitor
has_related_synonym: alpha,alpha-trehalase (EC 3.2.1.28) inhibitors
has_related_synonym: alpha,alpha-trehalase inhibitor
has_related_synonym: alpha,alpha-trehalase inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

nonstructural protein 5A inhibitor
type: Class
subclass of: antiviral agent
subclass of: inhibitor
subclass of: biochemical role
definition: Any inhibitor of nonstructural protein 5A.
id: CHEBI:83799
has_related_synonym: HCV non-structural protein 5A inhibitor
has_related_synonym: HCV non-structural protein 5A inhibitors
has_related_synonym: NS5A inhibitor
has_related_synonym: NS5A inhibitors
has_related_synonym: NS5A replication complex inhibitor
has_related_synonym: NS5A replication complex inhibitors
database_cross_reference: Wikipedia:NS5A
has_obo_namespace: chebi_ontology
has_related_synonym: nonstructural protein 5A inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 4.2.1.94 (scytalone dehydratase) inhibitor
type: Class
subclass of: EC 4.2.1.* (hydro-lyases) inhibitor
definition: An EC 4.2.1.* (hydro-lyases) inhibitor that interferes with the action of scytalone dehydratase (EC 4.2.1.94).
id: CHEBI:84012
has_related_synonym: EC 4.2.1.94 (scytalone dehydratase) inhibitors
has_related_synonym: EC 4.2.1.94 inhibitor
has_related_synonym: EC 4.2.1.94 inhibitors
database_cross_reference: Wikipedia:Scytalone_dehydratase
has_obo_namespace: chebi_ontology
has_related_synonym: scytalone 7,8-hydro-lyase (1,3,8-trihydroxynaphthalene-forming) inhibitor
has_related_synonym: scytalone 7,8-hydro-lyase (1,3,8-trihydroxynaphthalene-forming) inhibitors
has_related_synonym: scytalone 7,8-hydro-lyase inhibitor
has_related_synonym: scytalone 7,8-hydro-lyase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.24.24 (gelatinase A) inhibitor
type: Class
subclass of: EC 3.4.24.* (metalloendopeptidase) inhibitor
has_related_synonym: 72 kDa gelatinase inhibitor
has_related_synonym: 72 kDa gelatinase inhibitors
has_related_synonym: 72 kDa gelatinase type A inhibitor
has_related_synonym: 72 kDa gelatinase type A inhibitors
definition: An EC 3.4.24.* (metalloendopeptidase) inhibitor that interferes with the action of gelatinase A (EC 3.4.24.24).
id: CHEBI:84036
has_related_synonym: EC 3.4.24.35 (gelatinase B) inhibitors
has_related_synonym: EC 3.4.24.35 inhibitor
has_related_synonym: EC 3.4.24.35 inhibitors
has_related_synonym: MMP 2 inhibitor
has_related_synonym: MMP 2 inhibitors
database_cross_reference: Wikipedia:MMP2
has_obo_namespace: chebi_ontology
has_related_synonym: collagenase IV inhibitor
has_related_synonym: collagenase IV inhibitors
has_related_synonym: collagenase type IV inhibitor
has_related_synonym: collagenase type IV inhibitors
has_related_synonym: matrix metalloproteinase 2 inhibitor
has_related_synonym: matrix metalloproteinase 2 inhibitors
has_related_synonym: type IV collagen metalloproteinase inhibitor
has_related_synonym: type IV collagen metalloproteinase inhibitors
has_related_synonym: type IV collagenase inhibitor
has_related_synonym: type IV collagenase inhibitors
has_related_synonym: type IV collagenase/gelatinase inhibitor
has_related_synonym: type IV collagenase/gelatinase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

human urinary metabolite
type: Class
subclass of: human metabolite
definition: Any metabolite (endogenous or exogenous) found in human urine samples.
id: CHEBI:84087
has_obo_namespace: chebi_ontology
has_related_synonym: human urinary metabolites
in_subset: 3 STAR
imported from: chebi.owl

EC 3.5.1.19 (nicotinamidase) inhibitor
type: Class
subclass of: EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor
definition: An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of nicotinamidase (EC 3.5.1.19).
id: CHEBI:84264
has_related_synonym: EC 3.5.1.19 (nicotinamidase) inhibitors
has_related_synonym: EC 3.5.1.19 inhibitor
has_related_synonym: EC 3.5.1.19 inhibitors
database_cross_reference: Wikipedia:Nicotinamidase
has_related_synonym: YNDase inhibitor
has_related_synonym: YNDase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: nicotinamidase (EC 3.5.1.19) inhibitor
has_related_synonym: nicotinamidase (EC 3.5.1.19) inhibitors
has_related_synonym: nicotinamidase inhibitor
has_related_synonym: nicotinamidase inhibitors
has_related_synonym: nicotinamide amidase inhibitor
has_related_synonym: nicotinamide amidase inhibitors
has_related_synonym: nicotinamide amidohydrolase inhibitor
has_related_synonym: nicotinamide amidohydrolase inhibitors
has_related_synonym: nicotinamide deaminase inhibitor
has_related_synonym: nicotinamide deaminase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.21.64 (peptidase K) inhibitor
type: Class
subclass of: protease inhibitor
subclass of: EC 3.4.21.* (serine endopeptidase) inhibitor
definition: An EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of peptidase K (EC 3.4.21.64).
id: CHEBI:84297
has_related_synonym: EC 3.4.21.64 (peptidase K) inhibitors
has_related_synonym: EC 3.4.21.64 inhibitor
has_related_synonym: EC 3.4.21.64 inhibitors
has_related_synonym: Tritirachium album proteinase K inhibitor
has_related_synonym: Tritirachium album proteinase K inhibitors
has_related_synonym: Tritirachium album serine proteinase inhibitor
has_related_synonym: Tritirachium album serine proteinase inhibitors
database_cross_reference: Wikipedia:Proteinase_K
has_obo_namespace: chebi_ontology
has_related_synonym: endopeptidase K inhibitor
has_related_synonym: endopeptidase K inhibitors
has_related_synonym: peptidase K inhibitor
has_related_synonym: peptidase K inhibitors
has_related_synonym: proteinase K inhibitor
has_related_synonym: proteinase K inhibitors
in_subset: 3 STAR
imported from: chebi.owl

algal metabolite
type: Class
subclass of: eukaryotic metabolite
definition: Any eukaryotic metabolite produced during a metabolic reaction in algae including unicellular organisms like chlorella and diatoms to multicellular organisms like giant kelps and brown algae.
id: CHEBI:84735
has_related_synonym: algal metabolites
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 2.3.1.5 (arylamine N-acetyltransferase) inhibitor
type: Class
subclass of: EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor
has_related_synonym: 2-naphthylamine N-acetyltransferase inhibitor
has_related_synonym: 2-naphthylamine N-acetyltransferase inhibitors
has_related_synonym: 4-aminobiphenyl N-acetyltransferase inhibitor
has_related_synonym: 4-aminobiphenyl N-acetyltransferase inhibitors
definition: An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of arylamine N-acetyltransferase (EC 2.3.1.5).
id: CHEBI:84799
has_related_synonym: EC 2.3.1.5 (arylamine N-acetyltransferase) inhibitors
has_related_synonym: EC 2.3.1.5 inhibitor
has_related_synonym: EC 2.3.1.5 inhibitora
has_related_synonym: N-acetyltransferase inhibitor
has_related_synonym: N-acetyltransferase inhibitors
database_cross_reference: PMID:18642144
database_cross_reference: PMID:21204000
database_cross_reference: Wikipedia:Arylamine_N-acetyltransferase
has_related_synonym: acetyl CoA-arylamine N-acetyltransferase inhibitor
has_related_synonym: acetyl CoA-arylamine N-acetyltransferase inhibitors
has_related_synonym: acetyl-CoA:arylamine N-acetyltransferase inhibitor
has_related_synonym: acetyl-CoA:arylamine N-acetyltransferase inhibitors
has_related_synonym: arylamine N-acetyltransferase (EC 2.3.1.5) inhibitor
has_related_synonym: arylamine N-acetyltransferase (EC 2.3.1.5) inhibitors
has_related_synonym: arylamine N-acetyltransferase inhibitor
has_related_synonym: arylamine N-acetyltransferase inhibitors
has_related_synonym: arylamine acetylase inhibitor
has_related_synonym: arylamine acetylase inhibitors
has_related_synonym: arylamine acetyltransferase inhibitor
has_related_synonym: arylamine acetyltransferase inhibitors
has_related_synonym: beta-naphthylamine N-acetyltransferase inhibitor
has_related_synonym: beta-naphthylamine N-acetyltransferase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: indoleamine N-acetyltransferase inhibitor
has_related_synonym: indoleamine N-acetyltransferase inhibitors
has_related_synonym: p-aminosalicylate N-acetyltransferase inhibitor
has_related_synonym: p-aminosalicylate N-acetyltransferase inhibitors
has_related_synonym: serotonin N-acetyltransferase inhibitor
has_related_synonym: serotonin N-acetyltransferase inhibitors
has_related_synonym: serotonin acetyltransferase inhibitor
has_related_synonym: serotonin acetyltransferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.4.1.1 (glycogen phosphorylase) inhibitor
type: Class
subclass of: EC 2.4.1.* (hexosyltransferase) inhibitor
has_related_synonym: (1->4)-alpha-D-glucan:phosphate alpha-D-glucosyltransferase inhibitor
has_related_synonym: (1->4)-alpha-D-glucan:phosphate alpha-D-glucosyltransferase inhibitors
has_related_synonym: 1,4-alpha-D-glucan:phosphate alpha-D-glucosyltransferase inhibitor
has_related_synonym: 1,4-alpha-D-glucan:phosphate alpha-D-glucosyltransferase inhibitors
has_related_synonym: 1,4-alpha-glucan phosphorylase inhibitor
has_related_synonym: 1,4-alpha-glucan phosphorylase inhibitors
definition: Any EC 2.4.1.* (hexosyltransferase) inhibitor that interferes with the action of glycogen phosphorylase (EC 2.4.1.1).
id: CHEBI:84800
has_related_synonym: EC 2.4.1.1 (glycogen phosphorylase) inhibitors
has_related_synonym: EC 2.4.1.1 inhibitor
has_related_synonym: EC 2.4.1.1 inhibitors
database_cross_reference: Wikipedia:Glycogen_phosphorylase
has_related_synonym: alpha-glucan phosphorylase inhibitor
has_related_synonym: alpha-glucan phosphorylase inhibitors
has_related_synonym: amylopectin phosphorylase inhibitor
has_related_synonym: amylopectin phosphorylase inhibitors
has_related_synonym: amylophosphorylase inhibitor
has_related_synonym: amylophosphorylase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: glucan phosphorylase inhibitor
has_related_synonym: glucan phosphorylase inhibitors
has_related_synonym: glucosan phosphorylase inhibitor
has_related_synonym: glucosan phosphorylase inhibitors
has_related_synonym: glycogen phosphorylase (EC 2.4.1.1) inhibitor
has_related_synonym: glycogen phosphorylase (EC 2.4.1.1) inhibitors
has_related_synonym: glycogen phosphorylase inhibitor
has_related_synonym: glycogen phosphorylase inhibitors
has_related_synonym: granulose phosphorylase inhibitor
has_related_synonym: granulose phosphorylase inhibitors
has_related_synonym: maltodextrin phosphorylase inhibitor
has_related_synonym: maltodextrin phosphorylase inhibitors
has_related_synonym: muscle phosphorylase a and b inhibitor
has_related_synonym: muscle phosphorylase a and b inhibitors
has_related_synonym: muscle phosphorylase inhibitor
has_related_synonym: muscle phosphorylase inhibitors
has_related_synonym: myophosphorylase inhibitor
has_related_synonym: myophosphorylase inhibitors
has_related_synonym: phosphorylase inhibitor
has_related_synonym: phosphorylase inhibitors
has_related_synonym: polyphosphorylase inhibitor
has_related_synonym: polyphosphorylase inhibitors
has_related_synonym: potato phosphorylase inhibitor
has_related_synonym: potato phosphorylase inhibitors
has_related_synonym: starch phosphorylase inhibitor
has_related_synonym: starch phosphorylase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.1.127 (inositol-trisphosphate 3-kinase) inhibitor
type: Class
subclass of: EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor
has_related_synonym: 1D-myo-inositol-trisphosphate 3-kinase inhibitor
has_related_synonym: 1D-myo-inositol-trisphosphate 3-kinase inhibitors
has_related_synonym: ATP:1D-myo-inositol-1,4,5-trisphosphate 3-phosphotransferase inhibitor
has_related_synonym: ATP:1D-myo-inositol-1,4,5-trisphosphate 3-phosphotransferase inhibitors
definition: Any EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor that interferes with the action of inositol-trisphosphate 3-kinase (EC 2.7.1.127).
id: CHEBI:84801
has_related_synonym: EC 2.7.1.127 (inositol-trisphosphate 3-kinase) inhibitors
has_related_synonym: EC 2.7.1.127 inhibitor
has_related_synonym: EC 2.7.1.127 inhibitors
has_related_synonym: IP3 3-kinase inhibitor
has_related_synonym: IP3 3-kinase inhibitors
has_related_synonym: IP3K inhibitor
has_related_synonym: IP3K inhibitors
has_related_synonym: Ins(1,4,5)P3 3-kinase inhibitor
has_related_synonym: Ins(1,4,5)P3 3-kinase inhibitors
database_cross_reference: Wikipedia:Inositol-trisphosphate_3-kinase
has_obo_namespace: chebi_ontology
has_related_synonym: inositol 1,4,5-trisphosphate 3-kinase inhibitor
has_related_synonym: inositol 1,4,5-trisphosphate 3-kinase inhibitors
has_related_synonym: inositol-trisphosphate 3-kinase (EC 2.7.1.127) inhibitor
has_related_synonym: inositol-trisphosphate 3-kinase (EC 2.7.1.127) inhibitors
has_related_synonym: inositol-trisphosphate 3-kinase inhibitor
has_related_synonym: inositol-trisphosphate 3-kinase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.1.151 (inositol-polyphosphate multikinase) inhibitor
type: Class
subclass of: EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor
has_related_synonym: ATP:1D-myo-inositol-1,4,5-trisphosphate 6-phosphotransferase inhibitor
has_related_synonym: ATP:1D-myo-inositol-1,4,5-trisphosphate 6-phosphotransferase inhibitors
definition: Any EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor that interferes with the action of inositol-polyphosphate multikinase (EC 2.7.1.151).
has_related_synonym: ArgRIII inhibitor
has_related_synonym: ArgRIII inhibitors
has_related_synonym: AtIpk2alpha inhibitor
has_related_synonym: AtIpk2alpha inhibitors
has_related_synonym: AtIpk2beta inhibitor
has_related_synonym: AtIpk2beta inhibitors
id: CHEBI:84802
has_related_synonym: EC 2.7.1.151 (inositol-polyphosphate multikinase) inhibitors
has_related_synonym: EC 2.7.1.151 inhibitor
has_related_synonym: EC 2.7.1.151 inhibitors
has_related_synonym: IP3/IP4 6-/3-kinase inhibitor
has_related_synonym: IP3/IP4 6-/3-kinase inhibitors
has_related_synonym: IP3/IP4 dual-specificity 6-/3-kinase inhibitor
has_related_synonym: IP3/IP4 dual-specificity 6-/3-kinase inhibitors
has_related_synonym: IpK2 inhibitor
has_related_synonym: IpK2 inhibitors
has_related_synonym: IpmK inhibitor
has_related_synonym: IpmK inhibitors
database_cross_reference: Wikipedia:Inositol-polyphosphate_multikinase
has_obo_namespace: chebi_ontology
has_related_synonym: inositol polyphosphate 6-/3-/5-kinase inhibitor
has_related_synonym: inositol polyphosphate 6-/3-/5-kinase inhibitors
has_related_synonym: inositol-polyphosphate multikinase (EC 2.7.1.151) inhibitor
has_related_synonym: inositol-polyphosphate multikinase (EC 2.7.1.151) inhibitors
has_related_synonym: inositol-polyphosphate multikinase inhibitor
has_related_synonym: inositol-polyphosphate multikinase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.4.* (phosphotransferases with a phosphate group as acceptor) inhibitor
type: Class
subclass of: EC 2.7.* (P-containing group transferase) inhibitor
definition: Any EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any phosphotransferase with a phosphate group as acceptor (EC 2.7.4.*).
id: CHEBI:84803
has_related_synonym: EC 2.7.4.* (phosphotransferases with a phosphate group as acceptor) inhibitors
has_related_synonym: EC 2.7.4.* inhibitor
has_related_synonym: EC 2.7.4.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: phosphotransferases with a phosphate group as acceptor (EC 2.7.4.*) inhibitor
has_related_synonym: phosphotransferases with a phosphate group as acceptor (EC 2.7.4.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.4.6 (nucleoside-diphosphate kinase) inhibitor
type: Class
subclass of: EC 2.7.4.* (phosphotransferases with a phosphate group as acceptor) inhibitor
has_related_synonym: ATP:nucleoside-diphosphate phosphotransferase inhibitor
has_related_synonym: ATP:nucleoside-diphosphate phosphotransferase inhibitors
definition: Any EC 2.7.4.* (phosphotransferases with a phosphate group as acceptor) inhibitor that interferes with the action of nucleoside-diphosphate kinase (EC 2.7.4.6).
id: CHEBI:84804
has_related_synonym: EC 2.7.4.6 (nucleoside-diphosphate kinase) inhibitors
has_related_synonym: EC 2.7.4.6 inhibitor
has_related_synonym: EC 2.7.4.6 inhibitors
has_related_synonym: UDP kinase inhibitor
has_related_synonym: UDP kinase inhibitors
database_cross_reference: Wikipedia:Nucleoside-diphosphate_kinase
has_obo_namespace: chebi_ontology
has_related_synonym: nucleoside 5'-diphosphate kinase inhibitor
has_related_synonym: nucleoside 5'-diphosphate kinase inhibitors
has_related_synonym: nucleoside diphosphate (UDP) kinase inhibitor
has_related_synonym: nucleoside diphosphate (UDP) kinase inhibitors
has_related_synonym: nucleoside diphosphokinase inhibitor
has_related_synonym: nucleoside diphosphokinase inhibitors
has_related_synonym: nucleoside-diphosphate kinase (EC 2.7.4.6) inhibitor
has_related_synonym: nucleoside-diphosphate kinase (EC 2.7.4.6) inhibitors
has_related_synonym: nucleoside-diphosphate kinase inhibitor
has_related_synonym: nucleoside-diphosphate kinase inhibitors
has_related_synonym: nucleotide phosphate kinase inhibitor
has_related_synonym: nucleotide phosphate kinase inhibitors
has_related_synonym: uridine diphosphate kinase inhibitor
has_related_synonym: uridine diphosphate kinase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.6.1.16 (glutamine--fructose-6-phosphate transaminase (isomerizing)) inhibitor
type: Class
subclass of: EC 2.6.1.* (transaminase) inhibitor
definition: An EC 2.6.1.* (transaminase) inhibitor that interferes with the action of glutamine--fructose-6-phosphate transaminase (isomerizing) (EC 2.6.1.19).
id: CHEBI:85011
has_related_synonym: D-fructose-6-phosphate amidotransferase inhibitor
has_related_synonym: D-fructose-6-phosphate amidotransferase inhibitors
has_related_synonym: EC 2.6.1.16 (glutamine--fructose-6-phosphate transaminase (isomerizing)) inhibitors
has_related_synonym: EC 2.6.1.16 inhibitor
has_related_synonym: EC 2.6.1.16 inhibitors
has_related_synonym: GlcN6P synthase inhibitor
has_related_synonym: GlcN6P synthase inhibitors
has_related_synonym: L-glutamine-D-fructose-6-phosphate amidotransferase inhibitor
has_related_synonym: L-glutamine-D-fructose-6-phosphate amidotransferase inhibitors
has_related_synonym: L-glutamine:D-fructose-6-phosphate isomerase (deaminating) inhibitor
has_related_synonym: L-glutamine:D-fructose-6-phosphate isomerase (deaminating) inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: glucosamine 6-phosphate synthase inhibitor
has_related_synonym: glucosamine 6-phosphate synthase inhibitors
has_related_synonym: glucosamine-6-phosphate isomerase (glutamine-forming) inhibitor
has_related_synonym: glucosamine-6-phosphate isomerase (glutamine-forming) inhibitors
has_related_synonym: glucosamine-6-phosphate synthase inhibitor
has_related_synonym: glucosamine-6-phosphate synthase inhibitors
has_related_synonym: glucosaminephosphate isomerase inhibitor
has_related_synonym: glucosaminephosphate isomerase inhibitors
has_related_synonym: hexosephosphate aminotransferase inhibitor
has_related_synonym: hexosephosphate aminotransferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

thrombopoietin receptor agonist
type: Class
subclass of: agonist
definition: An agonist that selectively binds to and activates the thrombopoietin receptor [myeloproliferative leukemia protein or CD110 (Cluster of Differentiation 110)].
id: CHEBI:85012
has_related_synonym: TPO receptor agonist
has_related_synonym: TPO receptor agonists
has_obo_namespace: chebi_ontology
has_related_synonym: thrombopoietin receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

skin lightening agent
type: Class
subclass of: cosmetic
definition: Any cosmetic used to lighten the colour of skin by reducing the concentration of melanin.
id: CHEBI:85046
database_cross_reference: PMID:21265866
database_cross_reference: PMID:22132817
database_cross_reference: PMID:22314516
database_cross_reference: PMID:23891889
database_cross_reference: PMID:23974587
database_cross_reference: PMID:25535470
database_cross_reference: PMID:25574195
database_cross_reference: PMID:25643794
database_cross_reference: Wikipedia:Skin_whitening
has_obo_namespace: chebi_ontology
has_related_synonym: melanogenesis inhibitor
has_related_synonym: melanogenesis inhibitors
has_related_synonym: skin bleaching agent
has_related_synonym: skin bleaching agents
has_related_synonym: skin depigmenting agent
has_related_synonym: skin depigmenting agents
has_related_synonym: skin lightening agents
has_related_synonym: skin whitening agent
has_related_synonym: skin whitening agents
in_subset: 3 STAR
imported from: chebi.owl

EC 1.10.3.* (oxidoreductase acting on diphenols and related substances as donors with oxygen as acceptor) inhibitor
type: Class
subclass of: EC 1.10.* (oxidoreductase acting on diphenols and related substances as donors) inhibitor
definition: An EC 1.10.* (oxidoreductase acting on diphenols and related substances as donors) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.10.3.*).
id: CHEBI:85048
has_related_synonym: EC 1.10.3.* (oxidoreductase acting on diphenols and related substances as donors with oxygen as acceptor) inhibitors
has_related_synonym: EC 1.10.3.* inhibitor
has_related_synonym: EC 1.10.3.* inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 1.10.3.1 (catechol oxidase) inhibitor
type: Class
subclass of: EC 1.10.3.* (oxidoreductase acting on diphenols and related substances as donors with oxygen as acceptor) inhibitor
has_related_synonym: 1,2-benzenediol:oxygen oxidoreductase inhibitor
has_related_synonym: 1,2-benzenediol:oxygen oxidoreductase inhibitors
definition: Any EC 1.10.3.* (oxidoreductase acting on diphenols and related substances as donors with oxygen as acceptor) inhibitor that interferes with the action of catechol oxidase (EC 1.10.3.1).
id: CHEBI:85049
has_related_synonym: Dopa oxidase inhibitor
has_related_synonym: Dopa oxidase inhibitors
has_related_synonym: EC 1.10.3.1 (catechol oxidase) inhibitors
has_related_synonym: EC 1.10.3.1 inhibitor
has_related_synonym: EC 1.10.3.1 inhibitors
database_cross_reference: Wikipedia:Catechol_oxidase
has_related_synonym: catechol oxidase (EC 1.10.3.1) inhibitor
has_related_synonym: catechol oxidase (EC 1.10.3.1) inhibitors
has_related_synonym: catechol oxidase inhibitor
has_related_synonym: catechol oxidase inhibitors
has_related_synonym: catecholase inhibitor
has_related_synonym: catecholase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: diphenol oxidase inhibitor
has_related_synonym: diphenol oxidase inhibitors
has_related_synonym: o-diphenol oxidoreductase inhibitor
has_related_synonym: o-diphenol oxidoreductase inhibitors
has_related_synonym: o-diphenol:oxygen oxidoreductase inhibitor
has_related_synonym: o-diphenol:oxygen oxidoreductase inhibitors
has_related_synonym: o-diphenolase inhibitor
has_related_synonym: o-diphenolase inhibitors
has_related_synonym: phenolase inhibitor
has_related_synonym: phenolase inhibitors
has_related_synonym: polyphenol oxidase inhibitor
has_related_synonym: polyphenol oxidase inhibitors
has_related_synonym: pyrocatechol oxidase inhibitor
has_related_synonym: pyrocatechol oxidase inhibitors
has_related_synonym: tyrosinase inhibitor
has_related_synonym: tyrosinase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.10.3.2 (laccase) inhibitor
type: Class
subclass of: EC 1.10.3.* (oxidoreductase acting on diphenols and related substances as donors with oxygen as acceptor) inhibitor
definition: Any EC 1.10.3.* (oxidoreductase acting on diphenols and related substances as donors with oxygen as acceptor) inhibitor that interferes with the action of laccase (EC 1.10.3.2).
id: CHEBI:85050
has_related_synonym: EC 1.10.3.2 (laccase) inhibitors
has_related_synonym: EC 1.10.3.2 inhibitor
has_related_synonym: EC 1.10.3.2 inhibitors
database_cross_reference: Wikipedia:Laccase
has_related_synonym: benzenediol:oxygen oxidoreductase inhibitor
has_related_synonym: benzenediol:oxygen oxidoreductase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: laccase (EC 1.10.3.2) inhibitor
has_related_synonym: laccase (EC 1.10.3.2) inhibitors
has_related_synonym: laccase inhibitor
has_related_synonym: laccase inhibitors
has_related_synonym: p-diphenol oxidase inhibitor
has_related_synonym: p-diphenol oxidase inhibitors
has_related_synonym: urishiol oxidase inhibitor
has_related_synonym: urishiol oxidase inhibitors
has_related_synonym: urushiol oxidase inhibitor
has_related_synonym: urushiol oxidase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.13.11.24 (quercetin 2,3-dioxygenase) inhibitor
type: Class
subclass of: EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitor
definition: Any EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitor that interferes with the action of quercetin 2,3-dioxygenase (EC 1.13.1.24).
id: CHEBI:85051
has_related_synonym: EC 1.13.11.24 (quercetin 2,3-dioxygenase) inhibitors
has_related_synonym: EC 1.13.11.24 inhibitor
has_related_synonym: EC 1.13.11.24 inhibitors
database_cross_reference: Wikipedia:Quercetin_2,3-dioxygenase
has_obo_namespace: chebi_ontology
has_related_synonym: flavonol 2,4-oxygenase inhibitor
has_related_synonym: flavonol 2,4-oxygenase inhibitors
has_related_synonym: quercetin 2,3-dioxygenase (EC 1.13.11.24) inhibitor
has_related_synonym: quercetin 2,3-dioxygenase (EC 1.13.11.24) inhibitors
has_related_synonym: quercetin 2,3-dioxygenase inhibitor
has_related_synonym: quercetin 2,3-dioxygenase inhibitors
has_related_synonym: quercetin:oxygen 2,3-oxidoreductase (decyclising) inhibitor
has_related_synonym: quercetin:oxygen 2,3-oxidoreductase (decyclising) inhibitors
has_related_synonym: quercetin:oxygen 2,3-oxidoreductase (decyclizing) inhibitor
has_related_synonym: quercetin:oxygen 2,3-oxidoreductase (decyclizing) inhibitors
has_related_synonym: quercetin:oxygen 2,3-oxidoreductase (ring-opening) inhibitor
has_related_synonym: quercetin:oxygen 2,3-oxidoreductase (ring-opening) inhibitors
has_related_synonym: quercetinase inhibitor
has_related_synonym: quercetinase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.4.3.3 (D-amino-acid oxidase) inhibitor
type: Class
subclass of: EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor
definition: Any EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor that interferes with the action of D-amino-acid oxidase (EC 1.4.3.3).
id: CHEBI:85052
has_related_synonym: D-amino-acid oxidase (EC 1.4.3.3) inhibitor
has_related_synonym: D-amino-acid oxidase (EC 1.4.3.3) inhibitors
has_related_synonym: D-amino-acid oxidase inhibitor
has_related_synonym: D-amino-acid oxidase inhibitors
has_related_synonym: D-amino-acid:oxygen oxidoreductase (deaminating) inhibitor
has_related_synonym: D-amino-acid:oxygen oxidoreductase (deaminating) inhibitors
has_related_synonym: EC 1.4.3.3 (D-amino-acid oxidase) inhibitors
has_related_synonym: EC 1.4.3.3 inhibitor
has_related_synonym: EC 1.4.3.3 inhibitors
has_related_synonym: L-amino acid:O2 oxidoreductase inhibitor
has_related_synonym: L-amino acid:O2 oxidoreductase inhibitors
database_cross_reference: Wikipedia:D-amino_acid_oxidase
has_obo_namespace: chebi_ontology
has_related_synonym: new yellow enzyme inhibitor
has_related_synonym: new yellow enzyme inhibitors
has_related_synonym: ophio-amino-acid oxidase inhibitor
has_related_synonym: ophio-amino-acid oxidase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.11.31 {[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase} activator
type: Class
subclass of: enzyme activator
has_related_synonym: 3-hydroxy-3-methylglutaryl coenzyme A reductase kinase activator
has_related_synonym: 3-hydroxy-3-methylglutaryl coenzyme A reductase kinase activators
has_related_synonym: 3-hydroxy-3-methylglutaryl-CoA reductase kinase activator
has_related_synonym: 3-hydroxy-3-methylglutaryl-CoA reductase kinase activators
has_related_synonym: AMP-activated protein kinase activator
has_related_synonym: AMP-activated protein kinase activators
has_related_synonym: AMPK activator
has_related_synonym: AMPK activators
has_related_synonym: ATP:[hydroxymethylglutaryl-CoA reductase (NADPH)] phosphotransferase activator
has_related_synonym: ATP:[hydroxymethylglutaryl-CoA reductase (NADPH)] phosphotransferase activators
definition: Any compound that binds to and activates the enzyme [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase (EC 2.7.11.31).
id: CHEBI:85053
has_related_synonym: EC 2.7.11.31 ([hydroxymethylglutaryl-CoA reductase (NADPH)] kinase) activator
has_related_synonym: EC 2.7.11.31 ([hydroxymethylglutaryl-CoA reductase (NADPH)] kinase) activators
has_related_synonym: EC 2.7.11.31 activator
has_related_synonym: EC 2.7.11.31 activators
has_related_synonym: EC 2.7.11.31 {[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase} activators
has_related_synonym: HMG-CoA reductase kinase activator
has_related_synonym: HMG-CoA reductase kinase activators
has_related_synonym: STK29 activator
has_related_synonym: STK29 activators
has_related_synonym: [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activator
has_related_synonym: [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activators
has_related_synonym: [hydroxymethylglutaryl-CoA reductase (NADPH2)] kinase activator
has_related_synonym: [hydroxymethylglutaryl-CoA reductase (NADPH2)] kinase activators
has_related_synonym: beta-hydroxy-beta-methylglutaryl-CoA reductase kinase activator
has_related_synonym: beta-hydroxy-beta-methylglutaryl-CoA reductase kinase activators
has_obo_namespace: chebi_ontology
has_related_synonym: hydroxymethylglutaryl coenzyme A reductase kinase (phosphorylating) activator
has_related_synonym: hydroxymethylglutaryl coenzyme A reductase kinase (phosphorylating) activators
has_related_synonym: hydroxymethylglutaryl coenzyme A reductase kinase activator
has_related_synonym: hydroxymethylglutaryl coenzyme A reductase kinase activators
has_related_synonym: hydroxymethylglutaryl-CoA reductase kinase activator
has_related_synonym: hydroxymethylglutaryl-CoA reductase kinase activators
has_related_synonym: reductase kinase activator
has_related_synonym: reductase kinase activators
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.11.11 (cAMP-dependent protein kinase) inhibitor
type: Class
subclass of: EC 2.7.11.* (protein-serine/threonine kinase) inhibitor
has_related_synonym: ATP:protein phosphotransferase (cAMP-dependent) inhibitor
has_related_synonym: ATP:protein phosphotransferase (cAMP-dependent) inhibitors
definition: An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of cAMP-dependent protein kinase (EC 2.7.11.11).
id: CHEBI:85094
has_related_synonym: EC 2.7.11.11 (cAMP-dependent protein kinase) inhibitors
has_related_synonym: EC 2.7.11.11 inhibitor
has_related_synonym: EC 2.7.11.11 inhibitors
has_related_synonym: PKA C inhibitor
has_related_synonym: PKA C inhibitors
has_related_synonym: PKA inhibitor
has_related_synonym: PKA inhibitors
has_related_synonym: STK22 inhibitor inhibitor
has_related_synonym: STK22 inhibitors inhibitors
database_cross_reference: Wikipedia:Protein_kinase_A
has_related_synonym: cAMP-dependent protein kinase (EC 2.7.11.11) inhibitor
has_related_synonym: cAMP-dependent protein kinase (EC 2.7.11.11) inhibitors
has_related_synonym: cAMP-dependent protein kinase inhibitor
has_related_synonym: cAMP-dependent protein kinase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: protein kinase A inhibitor
has_related_synonym: protein kinase A inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.11.12 (cGMP-dependent protein kinase) inhibitor
type: Class
subclass of: EC 2.7.11.* (protein-serine/threonine kinase) inhibitor
has_related_synonym: 3':5'-cyclic GMP-dependent protein kinase inhibitor
has_related_synonym: 3':5'-cyclic GMP-dependent protein kinase inhibitors
has_related_synonym: ATP:protein phosphotransferase (cGMP-dependent) inhibitor
has_related_synonym: ATP:protein phosphotransferase (cGMP-dependent) inhibitors
definition: An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of cGMP-dependent protein kinase (EC 2.7.11.12).
id: CHEBI:85113
has_related_synonym: EC 2.7.11.12 (cGMP-dependent protein kinase) inhibitors
has_related_synonym: EC 2.7.11.12 inhibitor
has_related_synonym: EC 2.7.11.12 inhibitors
has_related_synonym: PKG 1alpha inhibitor
has_related_synonym: PKG 1alpha inhibitors
has_related_synonym: PKG 1beta inhibitor
has_related_synonym: PKG 1beta inhibitors
has_related_synonym: PKG II inhibitor
has_related_synonym: PKG II inhibitors
has_related_synonym: PKG inhibitor
has_related_synonym: PKG inhibitors
has_related_synonym: STK23 inhibitor
has_related_synonym: STK23 inhibitors
database_cross_reference: Wikipedia:CGMP-dependent_protein_kinase
has_related_synonym: cGMP-dependent protein kinase (EC 2.7.11.12) inhibitor
has_related_synonym: cGMP-dependent protein kinase (EC 2.7.11.12) inhibitors
has_related_synonym: cGMP-dependent protein kinase Ibeta inhibitor
has_related_synonym: cGMP-dependent protein kinase Ibeta inhibitors
has_related_synonym: cGMP-dependent protein kinase inhibitor
has_related_synonym: cGMP-dependent protein kinase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: guanosine 3':5'-cyclic monophosphate-dependent protein kinase inhibitor
has_related_synonym: guanosine 3':5'-cyclic monophosphate-dependent protein kinase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

nonnucleoside hepatitis C virus polymerase inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
definition: Any inhibitor of nonnucleoside hepatitis C virus polymerase.
id: CHEBI:85180
has_related_synonym: NS5B inhibitor
has_related_synonym: NS5B inhibitors
database_cross_reference: Wikipedia:NS5B
has_obo_namespace: chebi_ontology
has_related_synonym: nonnucleoside hepatitis C virus polymerase inhibitors
has_related_synonym: nonstructural protein 5B inhibitor
has_related_synonym: nonstructural protein 5B inhibitors
in_subset: 3 STAR
imported from: chebi.owl

hepatitis C virus nonstructural protein 5A inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
definition: Any inhibitor of hepatitis C virus nonstructural protein 5A.
id: CHEBI:85185
has_related_synonym: NS5A inhibitor
has_related_synonym: NS5A inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: hepatitis C virus nonstructural protein 5A inhibitors
has_related_synonym: nonstructural protein 5A inhibitor
has_related_synonym: nonstructural protein 5A inhibitors
in_subset: 3 STAR
imported from: chebi.owl

human blood serum metabolite
type: Class
subclass of: human metabolite
definition: Any metabolite (endogenous or exogenous) found in human blood serum samples.
id: CHEBI:85234
has_obo_namespace: chebi_ontology
has_related_synonym: human blood serum metabolites
in_subset: 3 STAR
imported from: chebi.owl

GABA reuptake inhibitor
type: Class
subclass of: neurotransmitter agent
definition: A compound that inhibits the re-uptake of the neurotransmitter GABA from the synapse into the pre-synaptic neuron, so increasing the extracellular concentrations of the neurotransmitter and hence increasing neurotransmission.
id: CHEBI:85384
has_related_synonym: GABA re-uptake inhibitor
has_related_synonym: GABA re-uptake inhibitors
has_related_synonym: GABA reuptake inhibitors
database_cross_reference: Wikipedia:GABA_reuptake_inhibitor
has_obo_namespace: chebi_ontology
has_related_synonym: gamma-aminobutyric acid re-uptake inhibitor
has_related_synonym: gamma-aminobutyric acid re-uptake inhibitors
has_related_synonym: gamma-aminobutyric acid reuptake inhibitor
has_related_synonym: gamma-aminobutyric acid reuptake inhibitors
in_subset: 3 STAR
imported from: chebi.owl

glycine transporter 2 inhibitor
type: Class
subclass of: glycine transporter inhibitor
definition: Any glycine transporter inhibitor that interferes with the action of glycine 2 transporters.
id: CHEBI:85424
has_related_synonym: GlyT2 inhibitor
has_related_synonym: GlyT2 inhibitors
database_cross_reference: Wikipedia:Glycine_transporter_2
has_obo_namespace: chebi_ontology
has_related_synonym: glycine transporter 2 inhibitors
in_subset: 3 STAR
imported from: chebi.owl

glycine transporter inhibitor
type: Class
subclass of: inhibitor
definition: Any substance that inhibits the action of glycine transporters.
id: CHEBI:85425
has_obo_namespace: chebi_ontology
has_related_synonym: glycine transporter inhibitors
in_subset: 3 STAR
imported from: chebi.owl

thromboxane A2 antagonist
type: Class
subclass of: antagonist
definition: An antagonist that binds to and deactivates thromboxane A2 receptors.
id: CHEBI:85540
has_related_synonym: TXA2/PGH2 antagonist
has_related_synonym: TXA2/PGH2 antagonists
has_related_synonym: TXA2/PGH2 receptor antagonist
has_related_synonym: TXA2/PGH2 receptor antagonists
has_obo_namespace: chebi_ontology
has_related_synonym: thromboxane A2 antagonists
has_related_synonym: thromboxane A2 receptor antagonist
has_related_synonym: thromboxane A2 receptor antagonists
in_subset: 3 STAR
imported from: chebi.owl

EC 2.5.1.31 {ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific]} inhibitor
type: Class
subclass of: EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor
has_related_synonym: (2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate cistransferase (adding 8 isopentenyl units) inhibitor
has_related_synonym: (2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate cistransferase (adding 8 isopentenyl units) inhibitors
definition: An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific].
id: CHEBI:85618
has_related_synonym: EC 2.5.1.31 inhibitor
has_related_synonym: EC 2.5.1.31 inhibitors
has_related_synonym: EC 2.5.1.31 {ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific]} inhibitors
has_related_synonym: UPP synthetase inhibitor
has_related_synonym: UPP synthetase inhibitors
has_related_synonym: bactoprenyl-diphosphate synthase inhibitor
has_related_synonym: bactoprenyl-diphosphate synthase inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: ditrans,polycis-undecaprenyl-diphosphate synthase inhibitor
has_related_synonym: ditrans,polycis-undecaprenyl-diphosphate synthase inhibitors
has_related_synonym: ditrans,polycis-undecaprenylcistransferase inhibitor
has_related_synonym: ditrans,polycis-undecaprenylcistransferase inhibitors
has_related_synonym: undecaprenyl diphosphate synthetase inhibitor
has_related_synonym: undecaprenyl diphosphate synthetase inhibitors
has_related_synonym: undecaprenyl pyrophosphate synthase inhibitor
has_related_synonym: undecaprenyl pyrophosphate synthase inhibitors
has_related_synonym: undecaprenyl pyrophosphate synthetase inhibitor
has_related_synonym: undecaprenyl pyrophosphate synthetase inhibitors
has_related_synonym: undecaprenyl-diphosphate synthase inhibitor
has_related_synonym: undecaprenyl-diphosphate synthase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.4.1.* (oxidoreductase acting on donor CH-NH2 group; NAD(+) or NADP(+) as acceptor) inhibitor
type: Class
subclass of: EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor
definition: Any EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor that interferes with the action any such enzyme that has NAD(+) or NADP(+) as acceptor.
id: CHEBI:86009
has_related_synonym: EC 1.4.1.* (oxidoreductase acting on donor CH-NH2 group with NAD(+) or NADP(+) as acceptor) inhibitor
has_related_synonym: EC 1.4.1.* (oxidoreductase acting on donor CH-NH2 group with NAD(+) or NADP(+) as acceptor) inhibitors
has_related_synonym: EC 1.4.1.* (oxidoreductase acting on donor CH-NH2 group; NAD(+) or NADP(+) as acceptor) inhibitors
has_related_synonym: EC 1.4.1.* inhibitor
has_related_synonym: EC 1.4.1.* inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 1.4.1.3 {glutamate dehydrogenase [NAD(P)(+)]} inhibitor
type: Class
subclass of: EC 1.4.1.* (oxidoreductase acting on donor CH-NH2 group; NAD(+) or NADP(+) as acceptor) inhibitor
definition: An EC 1.4.1.* (oxidoreductase acting on donor CH-NH2 group; NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of glutamate dehydrogenase [NAD(P)(+)] (EC 1.4.1.3).
id: CHEBI:86010
has_related_synonym: EC 1.4.1.3 inhibitor
has_related_synonym: EC 1.4.1.3 inhibitors
has_related_synonym: EC 1.4.1.3 {glutamate dehydrogenase [NAD(P)(+)]} inhibitors
has_related_synonym: L-glutamate:NAD(P)(+) oxidoreductase (deaminating) inhibitor
has_related_synonym: L-glutamate:NAD(P)(+) oxidoreductase (deaminating) inhibitors
database_cross_reference: Wikipedia:Glutamate_dehydrogenase_1
has_obo_namespace: chebi_ontology
has_related_synonym: glutamate dehydrogenase [NAD(P)(+)] (EC 1.4.1.3) inhibitor
has_related_synonym: glutamate dehydrogenase [NAD(P)(+)] (EC 1.4.1.3) inhibitors
has_related_synonym: glutamate dehydrogenase [NAD(P)(+)] inhibitor
has_related_synonym: glutamate dehydrogenase [NAD(P)(+)] inhibitors
has_related_synonym: glutamic dehydrogenase inhibitor
has_related_synonym: glutamic dehydrogenase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

liver X receptor agonist
type: Class
subclass of: agonist
definition: Any compound that acts as an agonist towards the liver X receptors.
id: CHEBI:86029
has_related_synonym: LXR agonist
has_related_synonym: LXR agonists
database_cross_reference: Wikipedia:Liver_X_receptor
has_obo_namespace: chebi_ontology
has_related_synonym: liver X receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

rat metabolite
type: Class
subclass of: mammalian metabolite
definition: Any mammalian metabolite produced during a metabolic reaction in rat (Rattus norvegicus).
id: CHEBI:86264
has_related_synonym: Rattus norvegicus metabolite
has_related_synonym: Rattus norvegicus metabolites
has_obo_namespace: chebi_ontology
has_related_synonym: rat metabolites
in_subset: 3 STAR
imported from: chebi.owl

antifungal drug
type: Class
subclass of: drug
subclass of: antiinfective agent
subclass of: antifungal agent
definition: Any antifungal agent used to prevent or treat fungal infections in humans or animals.
id: CHEBI:86327
database_cross_reference: Wikipedia:Antifungal
has_related_synonym: anti-fungal drug
has_related_synonym: anti-fungal drugs
has_related_synonym: anti-fungal medication
has_related_synonym: anti-fungal medications
has_related_synonym: antifungal drugs
has_related_synonym: antifungal medication
has_related_synonym: antifungal medications
has_obo_namespace: chebi_ontology
has_related_synonym: pharmaceutical fungicide
has_related_synonym: pharmaceutical fungicides
in_subset: 3 STAR
imported from: chebi.owl

antifungal agrochemical
type: Class
subclass of: fungicide
subclass of: pesticide
subclass of: agrochemical
definition: Any substance used in acriculture, horticulture, forestry, etc. for its fungicidal properties.
id: CHEBI:86328
has_related_synonym: agrichemical fungicide
has_related_synonym: agrichemical fungicides
has_related_synonym: agrochemical fungicide
has_related_synonym: agrochemical fungicides
has_related_synonym: anti-fungal agrichemical
has_related_synonym: anti-fungal agrichemicals
has_related_synonym: anti-fungal agrochemical
has_related_synonym: anti-fungal agrochemicals
has_related_synonym: antifungal agrichemical
has_related_synonym: antifungal agrichemicals
has_related_synonym: antifungal agrochemicals
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 5.3.3.* (intramolecular oxidase transposing C=C bonds) inhibitor
type: Class
subclass of: EC 5.3.* (intramolecular oxidoreductase) inhibitor
definition: An EC 5.3.* (intramolecular oxidoreductase) inhibitor that inhibits the action of any such enzyme that transposes C=C bonds (EC 5.3.3.*).
id: CHEBI:86383
has_related_synonym: EC 5.3.3.* (intramolecular oxidase transposing C=C bonds) inhibitors
has_related_synonym: EC 5.3.3.* inhibitor
has_related_synonym: EC 5.3.3.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: intramolecular oxidase transposing C=C bonds inhibitor (EC 5.3.3.*) inhibitor
has_related_synonym: intramolecular oxidase transposing C=C bonds inhibitor (EC 5.3.3.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor
type: Class
subclass of: EC 5.3.3.* (intramolecular oxidase transposing C=C bonds) inhibitor
definition: An EC 5.3.3.* (intramolecular oxidase transposing C=C bonds) inhibitor that interferes with the action of a cholestenol Delta-isomerase (EC 5.3.3.5).
id: CHEBI:86385
has_related_synonym: Delta(7)-cholestenol Delta(7)-Delta(8)-isomerase inhibitor
has_related_synonym: Delta(7)-cholestenol Delta(7)-Delta(8)-isomerase inhibitors
has_related_synonym: EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitors
has_related_synonym: EC 5.3.3.5 inhibitor
has_related_synonym: EC 5.3.3.5 inhibitors
database_cross_reference: Wikipedia:Cholestenol_Delta-isomerase
has_obo_namespace: chebi_ontology
has_related_synonym: cholestenol Delta-isomerase (EC 5.3.3.5) inhibitor
has_related_synonym: cholestenol Delta-isomerase (EC 5.3.3.5) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.14.13.78 (ent-kaurene oxidase) inhibitor
type: Class
subclass of: EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor
definition: An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of ent-kaurene oxidase (E.C. 1.14.13.78).
id: CHEBI:86430
has_related_synonym: EC 1.14.13.78 (ent-kaurene oxidase) inhibitors
has_related_synonym: EC 1.14.13.78 inhibitor
has_related_synonym: EC 1.14.13.78 inhibitors
database_cross_reference: Wikipedia:Ent-kaurene_oxidase
has_obo_namespace: chebi_ontology
has_related_synonym: ent-kaurene oxidase (EC 1.14.13.78) inhibitor
has_related_synonym: ent-kaurene oxidase (EC 1.14.13.78) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.14.13.97 (taurochenodeoxycholate 6alpha-hydroxylase) inhibitor
type: Class
subclass of: EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor
definition: An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of EC 1.14.13.97 (taurochenodeoxycholate 6alpha-hydroxylase).
id: CHEBI:86501
has_related_synonym: CYP3A4 inhibitor
has_related_synonym: CYP3A4 inhibitors
has_related_synonym: CYP4A21 inhibitor
has_related_synonym: CYP4A21 inhibitors
has_related_synonym: EC 1.14.13.97 (taurochenodeoxycholate 6alpha-hydroxylase) inhibitors
has_related_synonym: EC 1.14.13.97 inhibitor
has_related_synonym: EC 1.14.13.97 inhibitors
database_cross_reference: Wikipedia:CYP3A4
has_obo_namespace: chebi_ontology
has_related_synonym: cytochrome P450 3A4 inhibitor
has_related_synonym: cytochrome P450 3A4 inhibitors
has_related_synonym: taurochenodeoxycholate 6alpha-hydroxylase inhibitor
has_related_synonym: taurochenodeoxycholate 6alpha-hydroxylase inhibitors
has_related_synonym: taurochenodeoxycholate 6alpha-monooxygenase inhibitor
has_related_synonym: taurochenodeoxycholate 6alpha-monooxygenase inhibitors
has_related_synonym: taurochenodeoxycholate,NADPH:oxygen oxidoreductase (6alpha-hydroxylating) inhibitor
has_related_synonym: taurochenodeoxycholate,NADPH:oxygen oxidoreductase (6alpha-hydroxylating) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 3.4.21.92 (endopeptidase Clp) inhibitor
type: Class
subclass of: EC 3.4.21.* (serine endopeptidase) inhibitor
has_related_synonym: ATP-dependent Clp protease inhibitor
has_related_synonym: ATP-dependent Clp protease inhibitors
definition: Any EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of endopeptidase Clp (EC 3.4.21.92).
id: CHEBI:86966
has_related_synonym: Clp protease inhibitor
has_related_synonym: Clp protease inhibitors
has_related_synonym: ClpP inhibitor
has_related_synonym: ClpP inhibitors
has_related_synonym: EC 3.4.21.92 (endopeptidase Clp) inhibitors
has_related_synonym: EC 3.4.21.92 inhibitor
has_related_synonym: EC 3.4.21.92 inhibitors
database_cross_reference: Wikipedia:ATP-dependent_Clp_protease_proteolytic_subunit
has_related_synonym: caseinolytic protease inhibitor
has_related_synonym: caseinolytic protease inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: endopeptidase Ti inhibitor
has_related_synonym: endopeptidase Ti inhibitors
has_related_synonym: protease Ti inhibitor
has_related_synonym: protease Ti inhibitors
in_subset: 3 STAR
imported from: chebi.owl

STAT3 inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
definition: An inhibitor of signal transducer and activator of transcription 3 (STAT3)
id: CHEBI:87183
has_related_synonym: STAT3 inhibitors
database_cross_reference: Wikipedia:STAT3
has_obo_namespace: chebi_ontology
has_related_synonym: signal transducer and activator of transcription 3 inhibitor
has_related_synonym: signal transducer and activator of transcription 3 inhibitors
in_subset: 3 STAR
imported from: chebi.owl

Smad3 inhibitor
type: Class
subclass of: inhibitor
definition: An inhibitor of the SMAD3 protein.
id: CHEBI:87588
has_related_synonym: Mothers against decapentaplegic homolog 3 inhibitors
has_related_synonym: Mothers against decapentaplegic homologue 3 inhibitor
has_related_synonym: Mothers against decapentaplegic homologue 3 inhibitors
has_related_synonym: SMAD family member 3 inhibitor
has_related_synonym: SMAD family member 3 inhibitors
has_related_synonym: SMAD3 inhibitors
has_exact_synonym: Smad3 inhibitor
has_related_synonym: Smad3 inhibitors
database_cross_reference: Wikipedia:Mothers_against_decapentaplegic_homolog_3
has_obo_namespace: chebi_ontology
has_related_synonym: mothers against decapentaplegic homolog 3 inhibitor
in_subset: 3 STAR
imported from: chebi.owl

signal transducer and activator of transcription 5 protein inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
definition: Any inhibitor of signal transducer and activator of transcription 5 protein
id: CHEBI:87786
has_related_synonym: STAT5 inhibitor
has_related_synonym: STAT5 inhibitors
database_cross_reference: Wikipedia:STAT5
has_obo_namespace: chebi_ontology
has_related_synonym: signal transducer and activator of transcription 5 protein inhibitors
in_subset: 3 STAR
imported from: chebi.owl

cyanotoxin
type: Class
subclass of: toxin
subclass of: bacterial metabolite
definition: Any toxin produced by cyanobacteria (blue-green algae).
id: CHEBI:88048
database_cross_reference: Wikipedia:Cyanotoxin
has_obo_namespace: chebi_ontology
has_related_synonym: cyanotoxins
in_subset: 3 STAR
imported from: chebi.owl

drug allergen
type: Class
subclass of: drug
subclass of: allergen
definition: Any drug which causes the onset of an allergic reaction.
id: CHEBI:88188
has_related_synonym: allergenic drug
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

potassium ionophore
type: Class
subclass of: ionophore
definition: Any ionophore capable of transportation of potassium ions across membranes.
id: CHEBI:88227
database_cross_reference: PMID:11841304
has_obo_namespace: chebi_ontology
has_related_synonym: potassium ionophores
in_subset: 3 STAR
imported from: chebi.owl

autophagy inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
definition: Any compound that inhibits the process of autophagy (the self-digestion of one or more components of a cell through the action of enzymes originating within the same cell).
id: CHEBI:88230
database_cross_reference: PMID:24830781
database_cross_reference: PMID:25727221
database_cross_reference: PMID:25793774
database_cross_reference: PMID:25896709
database_cross_reference: Wikipedia:Autophagy
has_related_synonym: autophagocytosis inhibitor
has_related_synonym: autophagocytosis inhibitors
has_related_synonym: autophagy inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.12.* [dual-specificity kinases (those acting on Ser/Thr and Tyr residues)] inhibitor
type: Class
subclass of: EC 2.7.* (P-containing group transferase) inhibitor
definition: An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of duals specificity kinases acting on Ser/Thr and Tyr residues.
id: CHEBI:88285
has_related_synonym: EC 2.7.12.* [dual-specificity kinases (those acting on Ser/Thr and Tyr residues)] inhibitors
has_related_synonym: EC 2.7.12.* inhibitor
has_related_synonym: EC 2.7.12.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: inhibitor of dual-specificity kinases (those acting on Ser/Thr and Tyr residues) (EC 2.7.12.*)
has_related_synonym: inhibitors of dual-specificity kinases (those acting on Ser/Thr and Tyr residues) (EC 2.7.12.*)
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.12.2 (mitogen-activated protein kinase kinase) inhibitor
type: Class
subclass of: EC 2.7.12.* [dual-specificity kinases (those acting on Ser/Thr and Tyr residues)] inhibitor
has_related_synonym: ATP:protein phosphotransferase (MAPKKK-activated) inhibitor
has_related_synonym: ATP:protein phosphotransferase (MAPKKK-activated) inhibitors
definition: An EC 2.7.12.* [dual-specificity kinases (those acting on Ser/Thr and Tyr residues)] inhibitor that inhibits the action of mitogen-activated protein kinase kinase (EC 2.7.12.2).
id: CHEBI:88286
has_related_synonym: EC 2.7.12.2 (mitogen-activated protein kinase kinase) inhibitors
has_related_synonym: EC 2.7.12.2 inhibitor
has_related_synonym: EC 2.7.12.2 inhibitors
has_related_synonym: MAP kinase kinase 4 inhibitor
has_related_synonym: MAP kinase kinase 4 inhibitors
has_related_synonym: MAP kinase kinase 7 inhibitor
has_related_synonym: MAP kinase kinase 7 inhibitors
has_related_synonym: MAP kinase kinase inhibitor
has_related_synonym: MAP kinase kinase inhibitors
has_related_synonym: MAP kinase or ERK kinase inhibitor
has_related_synonym: MAP kinase or ERK kinase inhibitors
has_related_synonym: MAP2K inhibitor
has_related_synonym: MAP2K inhibitors
has_related_synonym: MAPKK inhibitor
has_related_synonym: MAPKK inhibitors
has_related_synonym: MAPKK1 inhibitor
has_related_synonym: MAPKK1 inhibitors
has_related_synonym: MEK inhibitor
has_related_synonym: MEK inhibitors
has_related_synonym: MEK1 inhibitor
has_related_synonym: MEK1 inhibitors
has_related_synonym: MEK2 inhibitor
has_related_synonym: MEK2 inhibitors
has_related_synonym: MKK inhibitor
has_related_synonym: MKK inhibitors
has_related_synonym: MKK2 inhibitor
has_related_synonym: MKK2 inhibitors
has_related_synonym: MKK4 inhibitor
has_related_synonym: MKK4 inhibitors
has_related_synonym: MKK6 inhibitor
has_related_synonym: MKK6 inhibitors
has_related_synonym: MKK7 inhibitor
has_related_synonym: MKK7 inhibitors
has_related_synonym: STK27 inhibitor
has_related_synonym: STK27 inhibitors
database_cross_reference: Wikipedia:Mitogen-activated_protein_kinase_kinase
has_obo_namespace: chebi_ontology
has_related_synonym: mitogen-activated protein kinase kinase (EC 2.7.12.2) inhibitor
has_related_synonym: mitogen-activated protein kinase kinase (EC 2.7.12.2) inhibitors
has_related_synonym: mitogen-activated protein kinase kinase inhibitor
has_related_synonym: mitogen-activated protein kinase kinase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

G-protein-coupled receptor antagonist
type: Class
subclass of: antagonist
definition: An antagonist at G-protein-coupled receptor.
id: CHEBI:88295
has_related_synonym: G-protein-coupled receptor antagonists
has_related_synonym: GPCR antagonist
has_related_synonym: GPCR antagonists
database_cross_reference: Wikipedia:G_protein-coupled_receptor
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

retinoic acid receptor gamma agonist
type: Class
subclass of: retinoic acid receptor agonist
definition: Any retinoic acid receptor (RAR) agonist with specificity for RARgamma.
id: CHEBI:88336
has_related_synonym: NR1B3 agonist
has_related_synonym: NR1B3 agonists
database_cross_reference: PMID:11829754
has_related_synonym: RARgamma agonist
has_related_synonym: RARgamma agonists
database_cross_reference: Wikipedia:Retinoic_acid_receptor_gamma
has_obo_namespace: chebi_ontology
has_related_synonym: nuclear receptor subfamily 1, group B, member 3 agonist
has_related_synonym: nuclear receptor subfamily 1, group B, member 3 agonists
has_related_synonym: retinoic acid receptor gamma agonists
in_subset: 3 STAR
imported from: chebi.owl

alpha-secretase activator
type: Class
subclass of: enzyme activator
definition: An activator of alpha-secretase, one of the three endopeptidases that are specific for amyloid protein precursor and which have been identified based upon the region of the amyloid protein precursor which they cleave.
id: CHEBI:88355
database_cross_reference: PMID:19655822
database_cross_reference: PMID:22202113
database_cross_reference: Wikipedia:Alpha_secretase
has_related_synonym: alpha-secretase activators
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 1.1.1.170 [3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)] inhibitor
type: Class
subclass of: EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor
has_related_synonym: 3beta-hydroxy-4alpha-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating) inhibitor
has_related_synonym: 3beta-hydroxy-4alpha-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating) inhibitors
has_related_synonym: 3beta-hydroxy-4beta-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating) inhibitor
has_related_synonym: 3beta-hydroxy-4beta-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating) inhibitors
has_related_synonym: 3beta-hydroxy-4beta-methylcholestenoate dehydrogenase inhibitor
has_related_synonym: 3beta-hydroxy-4beta-methylcholestenoate dehydrogenase inhibitors
has_related_synonym: 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating) (EC 1.1.1.170) inhibitor
has_related_synonym: 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating) (EC 1.1.1.170) inhibitors
has_related_synonym: 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating) inhibitor
has_related_synonym: 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating) inhibitors
has_related_synonym: 3beta-hydroxysteroid-4alpha-carboxylate:NAD(P)(+) 3-oxidoreductase (decarboxylating) inhibitor
has_related_synonym: 3beta-hydroxysteroid-4alpha-carboxylate:NAD(P)(+) 3-oxidoreductase (decarboxylating) inhibitors
definition: An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating) (EC 1.1.1.170).
id: CHEBI:90113
has_related_synonym: EC 1.1.1.170 [3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)] inhibitors
has_related_synonym: EC 1.1.1.170 inhibitor
has_related_synonym: EC 1.1.1.170 inhibitors
database_cross_reference: Wikipedia:Sterol-4alpha-carboxylate_3-dehydrogenase_(decarboxylating)
has_obo_namespace: chebi_ontology
has_related_synonym: sterol 4alpha-carboxylic decarboxylase inhibitor
has_related_synonym: sterol 4alpha-carboxylic decarboxylase inhibitors
has_related_synonym: sterol-4alpha-carboxylate 3-dehydrogenase (decarboxylating) inhibitor
has_related_synonym: sterol-4alpha-carboxylate 3-dehydrogenase (decarboxylating) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

c-Jun N-terminal kinase inhibitor
type: Class
subclass of: EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
definition: An EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor that inhibits the action of c-Jun N-terminal kinase.
id: CHEBI:90172
has_related_synonym: JNK inhibitor
has_related_synonym: JNK inhibitors
database_cross_reference: Wikipedia:C-Jun_N-terminal_kinases
has_related_synonym: c-Jun N-terminal kinase inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 2.1.1.37 [DNA (cytosine-5-)-methyltransferase] inhibitor
type: Class
subclass of: EC 2.1.1.* (methyltransferases) inhibitor
definition: An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of DNA (cytosine-5-)-methyltransferase (EC 2.1.1.37).
id: CHEBI:90190
has_related_synonym: DNA 5-cytosine methylase inhibitor
has_related_synonym: DNA 5-cytosine methylase inhibitors
has_related_synonym: DNA cytosine c(5) methylase inhibitor
has_related_synonym: DNA cytosine c(5) methylase inhibitors
has_related_synonym: DNA cytosine methylase inhibitor
has_related_synonym: DNA cytosine methylase inhibitors
has_related_synonym: DNA methylase inhibitor
has_related_synonym: DNA methylase inhibitors
has_related_synonym: DNA methyltransferase inhibitor
has_related_synonym: DNA methyltransferase inhibitors
has_related_synonym: DNA transmethylase inhibitor
has_related_synonym: DNA transmethylase inhibitors
has_related_synonym: DNA-cytosine 5-methylase inhibitor
has_related_synonym: DNA-cytosine 5-methylase inhibitors
has_related_synonym: DNA-cytosine methyltransferase inhibitor
has_related_synonym: DNA-cytosine methyltransferase inhibitors
has_related_synonym: EC 2.1.1.37 [DNA (cytosine-5-)-methyltransferase] inhibitors
has_related_synonym: EC 2.1.1.37 inhibitor
has_related_synonym: EC 2.1.1.37 inhibitors
has_related_synonym: EcoRI methylase inhibitor
has_related_synonym: EcoRI methylase inhibitors
has_related_synonym: HpaII methylase inhibitor
has_related_synonym: HpaII methylase inhibitors
has_related_synonym: HpaII' methylase inhibitor
has_related_synonym: HpaII' methylase inhibitors
has_related_synonym: M.BsuRIa inhibitor
has_related_synonym: M.BsuRIa inhibitors
has_related_synonym: M.BsuRIb inhibitor
has_related_synonym: M.BsuRIb inhibitors
has_related_synonym: S-adenosyl-L-methionine:DNA (cytosine-5-)-methyltransferase inhibitor
has_related_synonym: S-adenosyl-L-methionine:DNA (cytosine-5-)-methyltransferase inhibitors
has_related_synonym: Typ II DNA methylase inhibitor
has_related_synonym: Typ II DNA methylase inhibitors
database_cross_reference: Wikipedia:DNMT1
has_obo_namespace: chebi_ontology
has_related_synonym: cytosine 5-methyltransferase inhibitor
has_related_synonym: cytosine 5-methyltransferase inhibitors
has_related_synonym: cytosine DNA methylase inhibitors
has_related_synonym: cytosine DNA methyltransferase inhibitor
has_related_synonym: cytosine DNA methyltransferase inhibitors
has_related_synonym: cytosine-specific DNA methyltransferase inhibitor
has_related_synonym: cytosine-specific DNA methyltransferase inhibitors
has_related_synonym: deoxyribonucleate methylase inhibitor
has_related_synonym: deoxyribonucleate methylase inhibitors
has_related_synonym: deoxyribonucleate methyltransferase inhibitor
has_related_synonym: deoxyribonucleate methyltransferase inhibitors
has_related_synonym: deoxyribonucleic (cytosine-5-)-methyltransferase inhibitor
has_related_synonym: deoxyribonucleic (cytosine-5-)-methyltransferase inhibitors
has_related_synonym: deoxyribonucleic acid (cytosine-5-)-methyltransferase inhibitor
has_related_synonym: deoxyribonucleic acid (cytosine-5-)-methyltransferase inhibitors
has_related_synonym: deoxyribonucleic acid methylase inhibitor
has_related_synonym: deoxyribonucleic acid methylase inhibitors
has_related_synonym: deoxyribonucleic acid methyltransferase inhibitor
has_related_synonym: deoxyribonucleic acid methyltransferase inhibitors
has_related_synonym: deoxyribonucleic acid modification methylase inhibitor
has_related_synonym: deoxyribonucleic acid modification methylase inhibitors
has_related_synonym: deoxyribonucleic methylase inhibitor
has_related_synonym: deoxyribonucleic methylase inhibitors
has_related_synonym: methylphosphotriester-DNA methyltransferase inhibitor
has_related_synonym: methylphosphotriester-DNA methyltransferase inhibitors
has_related_synonym: modification methylase inhibitor
has_related_synonym: modification methylase inhibitors
has_related_synonym: restriction-modification system inhibitor
has_related_synonym: restriction-modification system inhibitors
has_related_synonym: site-specific DNA-methyltransferase (cytosine-specific) inhibitor
has_related_synonym: site-specific DNA-methyltransferase (cytosine-specific) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

c-Met tyrosine kinase inhibitor
type: Class
subclass of: EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
definition: An EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor that interferes with the action of c-Met tyrosine kinase.
id: CHEBI:90199
has_related_synonym: MET inhibitor
has_related_synonym: MET inhibitors
has_related_synonym: MET proto-oncogene, receptor tyrosine kinase inhibitor
has_related_synonym: MET proto-oncogene, receptor tyrosine kinase inhibitors
database_cross_reference: Wikipedia:C-Met_inhibitors
has_related_synonym: c-Met inhibitor
has_related_synonym: c-Met inhibitors
has_related_synonym: c-Met tyrosine kinase inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

EC 4.1.1.23 (orotidine-5'-phosphate decarboxylase) inhibitor
type: Class
subclass of: EC 4.1.1.* (carboxy-lyase) inhibitor
definition: Any EC 4.1.1.* (carboxy-lyase) inhibitor that interferes with the action of orotidine-5'-phosphate decarboxylase (EC 4.1.1.23).
id: CHEBI:90285
has_related_synonym: EC 4.1.1.23 (orotidine-5'-phosphate decarboxylase) inhibitors
has_related_synonym: EC 4.1.1.23 inhibitor
has_related_synonym: EC 4.1.1.23 inhibitors
has_related_synonym: ODCase inhibitor
has_related_synonym: ODCase inhibitors
has_related_synonym: OMP decarboxylase inhibitor
has_related_synonym: OMP decarboxylase inhibitors
has_related_synonym: OMP-DC inhibitor
has_related_synonym: OMP-DC inhibitors
has_related_synonym: OMPdcase inhibitor
has_related_synonym: OMPdcase inhibitors
has_related_synonym: UMP synthase inhibitor
has_related_synonym: UMP synthase inhibitors
database_cross_reference: Wikipedia:Orotidine_5'-phosphate_decarboxylase
has_obo_namespace: chebi_ontology
has_related_synonym: orotate decarboxylase inhibitor
has_related_synonym: orotate decarboxylase inhibitors
has_related_synonym: orotate monophosphate decarboxylase inhibitor
has_related_synonym: orotate monophosphate decarboxylase inhibitors
has_related_synonym: orotic decarboxylase inhibitor
has_related_synonym: orotic decarboxylase inhibitors
has_related_synonym: orotidine 5'-phosphate decarboxylase inhibitor
has_related_synonym: orotidine 5'-phosphate decarboxylase inhibitors
has_related_synonym: orotidine monophosphate decarboxylase inhibitor
has_related_synonym: orotidine monophosphate decarboxylase inhibitors
has_related_synonym: orotidine phosphate decarboxylase inhibitor
has_related_synonym: orotidine phosphate decarboxylase inhibitors
has_related_synonym: orotidine-5'-monophosphate decarboxylase inhibitor
has_related_synonym: orotidine-5'-monophosphate decarboxylase inhibitors
has_related_synonym: orotidine-5'-phosphate carboxy-lyase (UMP-forming) inhibitor
has_related_synonym: orotidine-5'-phosphate carboxy-lyase (UMP-forming) inhibitors
has_related_synonym: orotidine-5'-phosphate carboxy-lyase inhibitor
has_related_synonym: orotidine-5'-phosphate carboxy-lyase inhibitors
has_related_synonym: orotidine-5'-phosphate decarboxylase (EC 4.1.1.23) inhibitor
has_related_synonym: orotidine-5'-phosphate decarboxylase (EC 4.1.1.23) inhibitors
has_related_synonym: orotidylic acid decarboxylase inhibitor
has_related_synonym: orotidylic acid decarboxylase inhibitors
has_related_synonym: orotidylic decarboxylase inhibitor
has_related_synonym: orotidylic decarboxylase inhibitors
has_related_synonym: orotodylate decarboxylase inhibitor
has_related_synonym: orotodylate decarboxylase inhibitors
has_related_synonym: uridine 5'-monophosphate synthase inhibitor
has_related_synonym: uridine 5'-monophosphate synthase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 6.4.1.1 (pyruvate carboxylase) inhibitor
type: Class
subclass of: EC 6.4.1.* (carboxylase) inhibitor
definition: An EC 6.4.1.* (carboxylase) inhibitor that interferes with the action of pyruvate carboxylase (EC 6.4.1.1).
id: CHEBI:90318
has_related_synonym: EC 6.4.1.1 (pyruvate carboxylase) inhibitors
has_related_synonym: EC 6.4.1.1 inhibitor
has_related_synonym: EC 6.4.1.1 inhibitors
database_cross_reference: Wikipedia:Pyruvate_carboxylase
has_obo_namespace: chebi_ontology
has_related_synonym: pyruvate carboxylase (EC 6.4.1.1) inhibitor
has_related_synonym: pyruvate carboxylase (EC 6.4.1.1) inhibitors
has_related_synonym: pyruvate carboxylase inhibitor
has_related_synonym: pyruvate carboxylase inhibitors
has_related_synonym: pyruvate:carbon-dioxide ligase (ADP-forming) inhibitor
has_related_synonym: pyruvate:carbon-dioxide ligase (ADP-forming) inhibitors
has_related_synonym: pyruvic carboxylase inhibitor
has_related_synonym: pyruvic carboxylase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 4.6.1.1 (adenylate cyclase) inhibitor
type: Class
subclass of: EC 4.6.* (P-O lyase) inhibitor
has_related_synonym: 3',5'-cyclic AMP synthetase inhibitor
has_related_synonym: 3',5'-cyclic AMP synthetase inhibitors
has_related_synonym: ATP diphosphate-lyase (cyclising) inhibitor
has_related_synonym: ATP diphosphate-lyase (cyclising) inhibitors
has_related_synonym: ATP diphosphate-lyase (cyclising; 3',5'-cyclic-AMP-forming) inhibitor
has_related_synonym: ATP diphosphate-lyase (cyclising; 3',5'-cyclic-AMP-forming) inhibitors
has_related_synonym: ATP diphosphate-lyase (cyclizing) inhibitor
has_related_synonym: ATP diphosphate-lyase (cyclizing) inhibitors
has_related_synonym: ATP diphosphate-lyase (cyclizing; 3',5'-cyclic-AMP-forming) inhibitor
has_related_synonym: ATP diphosphate-lyase (cyclizing; 3',5'-cyclic-AMP-forming) inhibitors
has_related_synonym: ATP pyrophosphate-lyase inhibitor
has_related_synonym: ATP pyrophosphate-lyase inhibitors
definition: An EC 4.6.* (P-O lyase) inhibitor that interferes with the action of enzyme adenylate cyclase (EC 4.6.1.1).
id: CHEBI:90365
has_related_synonym: EC 4.6.1.1 (adenylate cyclase) inhibitors
has_related_synonym: EC 4.6.1.1 inhibitor
has_related_synonym: EC 4.6.1.1 inhibitors
database_cross_reference: PMID:14979
database_cross_reference: PMID:24006339
database_cross_reference: PMID:25273392
database_cross_reference: PMID:25319071
database_cross_reference: Wikipedia:Adenylyl_cyclase
has_related_synonym: adenyl cyclase inhibitor
has_related_synonym: adenylate cyclase (EC 4.6.1.1) inhibitor
has_related_synonym: adenylate cyclase (EC 4.6.1.1) inhibitors
has_related_synonym: adenylate cyclase inhibitor
has_related_synonym: adenylate cyclase inhibitors
has_related_synonym: adenylyl cyclase inhibitor
has_related_synonym: adenylyl cyclase inhibitors
has_related_synonym: adenylylcyclase inhibitor
has_related_synonym: adenylylcyclase inhibitors
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

histone acetyltransferase activator
type: Class
subclass of: enzyme activator
definition: Any compound that binds to and activates the enzyme histone acetyltransferase (EC 2.3.1.48).
id: CHEBI:90374
has_related_synonym: HAT activator
has_related_synonym: HAT activators
database_cross_reference: Wikipedia:Histone_acetyltransferase
has_obo_namespace: chebi_ontology
has_related_synonym: histone acetyltransferase activators
in_subset: 3 STAR
imported from: chebi.owl

Sir1 inhibitor
type: Class
subclass of: EC 3.5.1.98 (histone deacetylase) inhibitor
definition: An EC 3.5.1.98 (histone deacetylase) inhibitor that interferes with the action of Sir1.
id: CHEBI:90375
has_related_synonym: SIRT1 inhibitor
has_related_synonym: SIRT1 inhibitors
has_related_synonym: Sir1 inhibitors
database_cross_reference: Wikipedia:Sirtuin_1
has_obo_namespace: chebi_ontology
has_related_synonym: sirtuin 1 inhibitor
has_related_synonym: sirtuin 1 inhibitors
in_subset: 3 STAR
imported from: chebi.owl

secretagogue
type: Class
subclass of: biochemical role
definition: A substance that causes another substance to be secreted.
id: CHEBI:90414
database_cross_reference: Wikipedia:Secretagogue
has_obo_namespace: chebi_ontology
has_related_synonym: secretagogues
in_subset: 3 STAR
imported from: chebi.owl

insulin secretagogue
type: Class
subclass of: secretagogue
definition: A secretagogue that causes the secretion of insulin.
id: CHEBI:90415
database_cross_reference: PMID:11235637
database_cross_reference: PMID:12365816
database_cross_reference: PMID:15989662
database_cross_reference: PMID:21185798
database_cross_reference: PMID:22563104
database_cross_reference: PMID:26229480
has_obo_namespace: chebi_ontology
has_related_synonym: insulin secretagogues
in_subset: 3 STAR
imported from: chebi.owl

EC 5.3.1.* (intramolecular oxidoreductase interconverting aldoses and ketoses) inhibitor
type: Class
subclass of: EC 5.3.* (intramolecular oxidoreductase) inhibitor
id: CHEBI:90689
has_obo_namespace: chebi_ontology
in_subset: 1 STAR
imported from: chebi.owl

EC 5.3.1.1 (triose-phosphate isomerase) inhibitor
type: Class
subclass of: EC 5.3.1.* (intramolecular oxidoreductase interconverting aldoses and ketoses) inhibitor
definition: Any EC 5.3.1.* (intramolecular oxidoreductase interconverting aldoses and ketoses) inhibitor that interferes with the action of a triose-phosphate isomerase (EC 5.3.1.1).
id: CHEBI:90691
has_related_synonym: D-glyceraldehyde-3-phosphate ketol-isomerase inhibitor
has_related_synonym: D-glyceraldehyde-3-phosphate ketol-isomerase inhibitors
has_related_synonym: EC 5.3.1.1 (triose-phosphate isomerase) inhibitors
has_related_synonym: EC 5.3.1.1 inhibitor
has_related_synonym: EC 5.3.1.1 inhibitors
database_cross_reference: Wikipedia:Triosephosphate_isomerase
has_obo_namespace: chebi_ontology
has_related_synonym: phosphotriose isomerase inhibitor
has_related_synonym: phosphotriose isomerase inhibitors
has_related_synonym: triose phosphate mutase inhibitor
has_related_synonym: triose phosphate mutase inhibitors
has_related_synonym: triose phosphoisomerase inhibitor
has_related_synonym: triose phosphoisomerase inhibitors
has_related_synonym: triose-phosphate isomerase (EC 5.3.1.1) inhibitor
has_related_synonym: triose-phosphate isomerase (EC 5.3.1.1) inhibitors
has_related_synonym: triose-phosphate isomerase inhibitor
has_related_synonym: triose-phosphate isomerase inhibitors
has_related_synonym: triosephosphate isomerase inhibitor
has_related_synonym: triosephosphate isomerase inhibitors
has_related_synonym: triosephosphate mutase inhibitor
has_related_synonym: triosephosphate mutase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

retinoic acid receptor modulator
type: Class
subclass of: nuclear receptor modulator
definition: A nuclear receptor modulator that affects the retinoic acid receptor
id: CHEBI:90708
has_obo_namespace: chebi_ontology
has_related_synonym: retinoic acid receptor modulators
in_subset: 3 STAR
imported from: chebi.owl

nuclear receptor modulator
type: Class
subclass of: receptor modulator
definition: Any receptor modulator acting on nuclear receptors
id: CHEBI:90709
has_obo_namespace: chebi_ontology
has_related_synonym: nuclear receptor modulators
in_subset: 3 STAR
imported from: chebi.owl

receptor modulator
type: Class
subclass of: drug
definition: A drug that acts as an antagonist, agonist, reverse agonist, or in some other fashion when interacting with cellular receptors.
has_alternative_id: CHEBI:189678
id: CHEBI:90710
database_cross_reference: Wikipedia:Receptor_modulator
has_obo_namespace: chebi_ontology
has_related_synonym: receptor modulators
in_subset: 3 STAR
imported from: chebi.owl

retinoic acid receptor alpha antagonist
type: Class
subclass of: retinoic acid receptor antagonist
definition: A retinoic acid receptor antagonist that antagonises retinoic acid receptor alpha.
id: CHEBI:90713
has_related_synonym: RAR alpha antagonist
has_related_synonym: RAR alpha antagonists
has_related_synonym: RARalpha antagonist
has_related_synonym: RARalpha antagonists
has_obo_namespace: chebi_ontology
has_related_synonym: retinoic acid receptor alpha antagonists
in_subset: 3 STAR
imported from: chebi.owl

retinoic acid receptor antagonist
type: Class
subclass of: antagonist
subclass of: retinoic acid receptor modulator
definition: An antagonist that acts at the retinoic acid receptor.
id: CHEBI:90714
has_related_synonym: RAR antagonist
has_related_synonym: RAR antagonists
has_obo_namespace: chebi_ontology
has_related_synonym: retinoic acid receptor antagonists
in_subset: 3 STAR
imported from: chebi.owl

retinoic acid receptor beta agonist
type: Class
subclass of: retinoic acid receptor agonist
definition: Any retinoic acid receptor (RAR) agonist with specificity for RARbeta.
id: CHEBI:90742
has_related_synonym: RAR beta agonist
has_related_synonym: RAR beta agonists
has_related_synonym: RARbeta agonist
has_related_synonym: RARbeta agonists
has_obo_namespace: chebi_ontology
has_related_synonym: retinoic acid receptor beta agonists
in_subset: 3 STAR
imported from: chebi.owl

retinoic acid receptor gamma antagonist
type: Class
subclass of: retinoic acid receptor antagonist
definition: A retinoic acid receptor antagonist that antagonises retinoic acid receptor gamma.
id: CHEBI:90744
has_related_synonym: RAR gamma antagonist
has_related_synonym: RAR gamma antagonists
has_related_synonym: RARgamma antagonist
has_related_synonym: RARgamma antagonists
has_obo_namespace: chebi_ontology
has_related_synonym: retinoic acid receptor gamma antagonists
in_subset: 3 STAR
imported from: chebi.owl

antidote to cyanide poisoning
type: Class
subclass of: antidote
definition: A role borne by a molecule that acts to counteract or neutralize the deleterious effects of cyanide.
id: CHEBI:90749
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

antidote to organophosphate poisoning
type: Class
subclass of: antidote
definition: A role borne by a molecule that acts to counteract or neutralise the deleterious effects of organophosphates or acetylcholinesterase inhibitors (nerve agents).
id: CHEBI:90753
has_alternative_id: CHEBI:90758
has_related_synonym: antidote to acetylcholinesterase inhibitor poisoning
has_related_synonym: antidote to nerve agents
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

antidote to opioid poisoning
type: Class
subclass of: antidote
definition: A role borne by a molecule that acts to counteract or neutralise the deleterious effects of opioids.
id: CHEBI:90755
database_cross_reference: PMID:24510187
database_cross_reference: PMID:24868924
has_related_synonym: antidote to opioid overdose
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

antidote to benzodiazepine poisoning
type: Class
subclass of: antidote
definition: A role borne by a molecule that acts to counteract or neutralise the deleterious effects of benzodiazepines.
id: CHEBI:90757
has_related_synonym: antidote to benzodiazepine overdose
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

eukaryotic translation elongation factor 1alpha 1 inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
definition: Any compound that inihibits the human protein, eukaryotic translation elongation factor 1alpha 1.
id: CHEBI:90767
has_related_synonym: EEF1A1 inhibitor
has_related_synonym: EEF1A1 inhibitors
database_cross_reference: Wikipedia:Eukaryotic_translation_elongation_factor_1_alpha_1
has_obo_namespace: chebi_ontology
has_related_synonym: eEF1A inhibitor
has_related_synonym: eEF1A inhibitors
has_related_synonym: eukaryotic translation elongation factor 1alpha 1 inhibitors
in_subset: 3 STAR
imported from: chebi.owl

AKT1 kinase inhibitor
type: Class
subclass of: EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor
definition: A serine/threonine kinase inhibitor that specifically inhibits RAC-alpha serine/threonine-protein kinase (ATK1).
has_related_synonym: AKT1 kinase inhibitors
id: CHEBI:90780
has_related_synonym: RAC-alpha serine/threonine-protein kinase inhibitor
has_related_synonym: RAC-alpha serine/threonine-protein kinase inhibitors
database_cross_reference: Wikipedia:AKT1
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

prostacyclin receptor agonist
type: Class
subclass of: agonist
definition: An agonist that binds to and activates prostacyclin receptors
id: CHEBI:90845
has_related_synonym: IP receptor agonist
has_related_synonym: IP receptor agonists
has_related_synonym: IP1 agonist
has_related_synonym: IP1 agonists
database_cross_reference: Wikipedia:Prostacyclin_receptor
has_obo_namespace: chebi_ontology
has_related_synonym: prostacyclin receptor I2 agonist
has_related_synonym: prostacyclin receptor I2 agonists
has_related_synonym: prostacyclin receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

liver X receptor inverse agonist
type: Class
subclass of: inverse agonist
definition: An inverse agonist that binds to the same receptor as a liver X receptor agonist, but which induces a pharmacological response opposite to that agonist.
id: CHEBI:90846
has_related_synonym: LXR inverse agonist
has_related_synonym: LXR inverse agonists
database_cross_reference: PMID:23237488
database_cross_reference: PMID:23665929
database_cross_reference: PMID:25830098
has_obo_namespace: chebi_ontology
has_related_synonym: liver X receptor inverse agonists
in_subset: 3 STAR
imported from: chebi.owl

inverse agonist
type: Class
subclass of: pharmacological role
definition: A substance that binds to the same receptor binding-site as an agonist for that receptor, but which exerts the opposite pharmacological effect.
id: CHEBI:90847
database_cross_reference: Wikipedia:Inverse_agonist
has_obo_namespace: chebi_ontology
has_related_synonym: inverse agonists
in_subset: 3 STAR
imported from: chebi.owl

EC 2.4.2.4 (thymidine phosphorylase) inhibitor
type: Class
subclass of: EC 2.4.2.* (pentosyltransferase) inhibitor
definition: An EC 2.4.2.* (pentosyltransferase) inhibitor that interferes with the action of thymidine phosphorylase (EC 2.4.2.4).
id: CHEBI:90878
has_related_synonym: EC 2.4.2.4 (thymidine phosphorylase) inhibitors
has_related_synonym: EC 2.4.2.4 inhibitor
has_related_synonym: EC 2.4.2.4 inhibitors
database_cross_reference: Wikipedia:Thymidine_phosphorylase
has_obo_namespace: chebi_ontology
has_related_synonym: deoxythymidine phosphorylase inhibitor
has_related_synonym: deoxythymidine phosphorylase inhibitors
has_related_synonym: pyrimidine deoxynucleoside phosphorylase inhibitor
has_related_synonym: pyrimidine deoxynucleoside phosphorylase inhibitors
has_related_synonym: pyrimidine phosphorylase inhibitor
has_related_synonym: pyrimidine phosphorylase inhibitors
has_related_synonym: thymidine phosphorylase inhibitor
has_related_synonym: thymidine phosphorylase inhibitors
has_related_synonym: thymidine-orthophosphate deoxyribosyltransferase inhibitor
has_related_synonym: thymidine-orthophosphate deoxyribosyltransferase inhibitors
has_related_synonym: thymidine:phosphate deoxy-D-ribosyltransferase inhibitor
has_related_synonym: thymidine:phosphate deoxy-D-ribosyltransferase inhibitors
has_related_synonym: thymidine:phosphate deoxy-alpha-D-ribosyltransferase inhibitor
has_related_synonym: thymidine:phosphate deoxy-alpha-D-ribosyltransferase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.8.5.* (oxidoreductase acting on sulfur group donors, quinone or similar as acceptor) inhibitor
type: Class
subclass of: EC 1.8.* (oxidoreductase acting on sulfur group of donors) inhibitor
definition: Any EC 1.8.* (oxidoreductase acting on sulfur group of donors) inhibitor that interferes with the action of any such enzyme using a quinone or similar compound as an acceptor.
id: CHEBI:90920
has_related_synonym: EC 1.8.5.* (oxidoreductase acting on sulfur group donors, quinone or similar as acceptor) inhibitors
has_related_synonym: EC 1.8.5.* inhibitor
has_related_synonym: EC 1.8.5.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: oxidoreductase acting on sulfur group donors, quinone or similar as acceptor (EC 1.8.5.*) inhibitor
has_related_synonym: oxidoreductase acting on sulfur group donors, quinone or similar as acceptor (EC 1.8.5.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.8.5.4 (sulfide:quinone reductase) inhibitor
type: Class
subclass of: EC 1.8.5.* (oxidoreductase acting on sulfur group donors, quinone or similar as acceptor) inhibitor
definition: An EC 1.8.5.* (oxidoreductase acting on sulfur group donors, quinone or similar as acceptor) inhibitor that interferes with the action of sulfide:quinone reductase (EC 1.8.5.4).
id: CHEBI:90921
has_related_synonym: EC 1.8.5.4 (sulfide:quinone reductase) inhibitors
has_related_synonym: EC 1.8.5.4 inhibitor
has_related_synonym: EC 1.8.5.4 inhibitors
database_cross_reference: Wikipedia:Sulfide:quinone_reductase
has_obo_namespace: chebi_ontology
has_related_synonym: sulfide:quinone oxidoreductase inhibitor
has_related_synonym: sulfide:quinone oxidoreductase inhibitors
has_related_synonym: sulfide:quinone reductase (EC 1.8.5.4) inhibitor
has_related_synonym: sulfide:quinone reductase (EC 1.8.5.4) inhibitors
has_related_synonym: sulfide:quinone reductase inhibitor
has_related_synonym: sulfide:quinone reductase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

ERK dimerisation inhibitor
type: Class
subclass of: inhibitor
definition: An inhibitor that interferes with the dimerisation of extracellular signal-regulated kinase (ERK).
id: CHEBI:90961
has_related_synonym: ERK dimerisation inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: extracellular signal-regulated kinase dimerisation inhibitor
has_related_synonym: extracellular signal-regulated kinase dimerisation inhibitors
in_subset: 3 STAR
imported from: chebi.owl

steroid receptor coactivator stimulator
type: Class
subclass of: biochemical role
definition: A compound that enhances the activity of a steroid receptor coactivator.
id: CHEBI:90991
database_cross_reference: PMID:26267537
has_related_synonym: SRC stimulator
has_related_synonym: SRC stimulators
has_obo_namespace: chebi_ontology
has_related_synonym: steroid receptor coactivator small molecule stimulator
has_related_synonym: steroid receptor coactivator small molecule stimulators
has_related_synonym: steroid receptor coactivator stimulators
in_subset: 3 STAR
imported from: chebi.owl

corrosion inhibitor
type: Class
subclass of: chemical role
definition: A chemical compound that, when added to a liquid or gas, decreases the corrosion rate of a material, typically a metal or an alloy.
id: CHEBI:91015
database_cross_reference: PMID:23636692
database_cross_reference: PMID:25594340
database_cross_reference: PMID:25839822
database_cross_reference: PMID:25912625
database_cross_reference: PMID:25955130
database_cross_reference: PMID:26160863
database_cross_reference: PMID:26343626
database_cross_reference: PMID:26347374
database_cross_reference: PMID:26364631
database_cross_reference: PMID:26727190
database_cross_reference: Wikipedia:Corrosion_inhibitor
has_obo_namespace: chebi_ontology
has_related_synonym: corrosion inhibitors
in_subset: 3 STAR
imported from: chebi.owl

GABAA receptor agonist
type: Class
subclass of: GABA agonist
definition: A GABA receptor agonist specific for GABAA receptors, ligand-gated ion channels (also known as ionotropic receptors).
id: CHEBI:91016
has_related_synonym: GABAA receptor agonists
has_obo_namespace: chebi_ontology
in_subset: 3 STAR
imported from: chebi.owl

erythropoietin inhibitor
type: Class
subclass of: inhibitor
definition: Any inhibitor of erythropoietin, a glycoprotein hormone that controls erythropoiesis (red blood cell production).
id: CHEBI:91025
has_related_synonym: EPO inhibitor
has_related_synonym: EPO inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: erythropoietin inhibitors
in_subset: 3 STAR
imported from: chebi.owl

purinergic receptor P2 antagonist
type: Class
subclass of: antagonist
definition: An antagonist at purinergic P2 receptors
id: CHEBI:91079
has_related_synonym: P2 antagonist
has_related_synonym: P2 antagonists
database_cross_reference: Wikipedia:Purinergic_receptor
has_obo_namespace: chebi_ontology
has_related_synonym: non-selective P2 purinergic antagonist
has_related_synonym: non-selective P2 purinergic antagonists
has_related_synonym: purinergic receptor P2 antagonists
in_subset: 3 STAR
imported from: chebi.owl

purinergic receptor P2X antagonist
type: Class
subclass of: purinergic receptor P2 antagonist
definition: An antagonist at purinergic P2X receptors
id: CHEBI:91081
has_related_synonym: P2X antagonist
has_related_synonym: P2X antagonists
has_obo_namespace: chebi_ontology
has_related_synonym: purinergic receptor P2X antagonists
in_subset: 3 STAR
imported from: chebi.owl

collagen cross-linking inhibitor
type: Class
subclass of: inhibitor
definition: Any compound that inhibits collagen cross-linking.
id: CHEBI:91085
has_obo_namespace: chebi_ontology
has_related_synonym: collagen cross-linking inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 2.7.11.26 (tau-protein kinase) inhibitor
type: Class
subclass of: EC 2.7.11.* (protein-serine/threonine kinase) inhibitor
has_related_synonym: ATP:[tau-protein] O-phosphotransferase inhibitor
has_related_synonym: ATP:[tau-protein] O-phosphotransferase inhibitors
has_related_synonym: ATP:tau-protein O-phosphotransferase inhibitor
has_related_synonym: ATP:tau-protein O-phosphotransferase inhibitors
definition: An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of tau-protein kinase inhibitor (EC 2.7.11.26).
has_related_synonym: CDK5/p23 inhibitor
has_related_synonym: CDK5/p23 inhibitors
id: CHEBI:91092
has_related_synonym: EC 2.7.11.26 (tau-protein kinase) inhibitors
has_related_synonym: EC 2.7.11.26 inhibitor
has_related_synonym: EC 2.7.11.26 inhibitors
has_related_synonym: GSK inhibitor
has_related_synonym: GSK inhibitors
has_related_synonym: GSK-3 inhibitor
has_related_synonym: GSK-3 inhibitors
has_related_synonym: STK31 inhibitor
has_related_synonym: STK31 inhibitors
has_related_synonym: TPK I inhibitor
has_related_synonym: TPK I inhibitors
has_related_synonym: TPK II inhibitor
has_related_synonym: TPK II inhibitors
has_related_synonym: TPK inhibitor
has_related_synonym: TPK inhibitors
has_related_synonym: TTK inhibitor
has_related_synonym: TTK inhibitors
database_cross_reference: Wikipedia:GSK-3
has_related_synonym: [tau-protein] kinase inhibitor
has_related_synonym: [tau-protein] kinase inhibitors
has_related_synonym: brain protein kinase PK40erk inhibitor
has_related_synonym: brain protein kinase PK40erk inhibitors
has_related_synonym: cdk5/p20 inhibitor
has_related_synonym: cdk5/p20 inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: glycogen synthase kinase-3beta inhibitor
has_related_synonym: glycogen synthase kinase-3beta inhibitors
has_related_synonym: protein tau kinase inhibitor
has_related_synonym: protein tau kinase inhibitors
has_related_synonym: tau kinase inhibitor
has_related_synonym: tau kinase inhibitors
has_related_synonym: tau-protein kinase I inhibitor
has_related_synonym: tau-protein kinase I inhibitors
has_related_synonym: tau-protein kinase II inhibitor
has_related_synonym: tau-protein kinase II inhibitors
has_related_synonym: tau-tubulin inhibitor
has_related_synonym: tau-tubulin inhibitors
in_subset: 3 STAR
imported from: chebi.owl

elastin-laminin receptor agonist
type: Class
subclass of: agonist
definition: An agonist that selectively binds to and activates elastin-laminin receptors.
id: CHEBI:91139
has_related_synonym: ELR agonist
has_related_synonym: ELR agonists
database_cross_reference: PMID:9856283
has_obo_namespace: chebi_ontology
has_related_synonym: elastin-laminin receptor agonists
in_subset: 3 STAR
imported from: chebi.owl

EC 1.1.5.3 (glycerol-3-phosphate dehydrogenase) inhibitor
type: Class
subclass of: EC 1.1.5.* (oxidoreductase acting on donor CH-OH group, quinone or similar compound as acceptor) inhibitor
definition: An EC 1.1.5.* (oxidoreductase acting on donor CH-OH group, quinone or similar compound as acceptor) inhibitor that interferes with the action of glycerol-3-phosphate dehydrogenase (EC 1.1.5.3).
id: CHEBI:91141
has_related_synonym: EC 1.1.5.3 (glycerol-3-phosphate dehydrogenase) inhibitors
has_related_synonym: EC 1.1.5.3 inhibitor
has_related_synonym: EC 1.1.5.3 inhibitors
database_cross_reference: Wikipedia:Glycerol-3-phosphate_dehydrogenase
has_obo_namespace: chebi_ontology
has_related_synonym: glycerol-3-phosphate dehydrogenase inhibitor
has_related_synonym: glycerol-3-phosphate dehydrogenase inhibitors
in_subset: 3 STAR
imported from: chebi.owl

EC 1.1.5.* (oxidoreductase acting on donor CH-OH group, quinone or similar compound as acceptor) inhibitor
type: Class
subclass of: EC 1.1.* (oxidoreductase acting on donor CH-OH group) inhibitor
definition: An EC 1.1.* (oxidoreductase acting on donor CH-OH group) inhibitor that interferes with the action of any such enzyme using a quinone or similar compound as acceptor (EC 1.1.5.*).
id: CHEBI:91142
has_related_synonym: EC 1.1.5.* (oxidoreductase acting on donor CH-OH group, quinone or simliar compound as acceptor) inhibitors
has_related_synonym: EC 1.1.5.* inhibitor
has_related_synonym: EC 1.1.5.* inhibitors
has_obo_namespace: chebi_ontology
has_related_synonym: oxidoreductase acting on donor CH-OH group, quinone or simliar compound as acceptor (EC 1.1.5.*) inhibitor
has_related_synonym: oxidoreductase acting on donor CH-OH group, quinone or simliar compound as acceptor (EC 1.1.5.*) inhibitors
in_subset: 3 STAR
imported from: chebi.owl

VEGF activator
type: Class
subclass of: activator
definition: Any activator of vascular endothelial growth factor (VEGF).
id: CHEBI:91189
has_related_synonym: VEGF activators
has_related_synonym: VEGF inducer
has_related_synonym: VEGF inducers
database_cross_reference: Wikipedia:Vascular_endothelial_growth_factor
has_obo_namespace: chebi_ontology
has_related_synonym: vascular endothelial growth factor activator
has_related_synonym: vascular endothelial growth factor activators
has_related_synonym: vascular endothelial growth factor inducer
has_related_synonym: vascular endothelial growth factor inducers
in_subset: 3 STAR
imported from: chebi.owl

lysophosphatidic acid receptor antagonist
type: Class
subclass of: antagonist
definition: An antagonist that binds to and deactivates lysophosphatidic acid receptors.
id: CHEBI:91193
has_related_synonym: LPA receptor antagonist
has_related_synonym: LPA receptor antagonists
has_related_synonym: LPAR antagonist
has_related_synonym: LPAR antagonists
has_obo_namespace: chebi_ontology
has_related_synonym: lysophosphatidic acid receptor antagonists
in_subset: 3 STAR
imported from: chebi.owl

TGFbeta receptor antagonist
type: Class
subclass of: EC 2.7.11.30 (receptor protein serine/threonine kinase) inhibitor
subclass of: antagonist
definition: An antagonist that binds to and deactivates TGFbeta receptors.
id: CHEBI:91202
has_related_synonym: TGFR antagonist
has_related_synonym: TGFR antagonists
has_related_synonym: TGFbeta receptor antagonists
database_cross_reference: Wikipedia:TGF_beta_receptors
has_obo_namespace: chebi_ontology
has_related_synonym: transforming growth factor receptor antagonist
has_related_synonym: transforming growth factor receptor antagonists
in_subset: 3 STAR
imported from: chebi.owl

macrophage migration inhibitory factor inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
definition: Any inhibitor of macrophage migration inhibitory factor (MIF).
id: CHEBI:91214
has_related_synonym: MIF inhibitor
has_related_synonym: MIF inhibitors
database_cross_reference: Wikipedia:Macrophage_migration_inhibitory_factor
has_obo_namespace: chebi_ontology
has_related_synonym: macrophage migration inhibitory factor inhibitors
in_subset: 3 STAR
imported from: chebi.owl

tienilic acid
type: Class
subclass of: molecular entity
has_related_synonym: (2,3-Dichloro-4-(2-thenoyl)phenoxy)acetic acid
has_related_synonym: (2,3-Dichloro-4-(2-thiophenecarbonyl)phenoxy)acetic acid
charge: 0
monoisotopicmass: 329.95204
mass: 331.17100
has_related_synonym: 4-(2-Theonyl)-2,3-dichlorphenoxyessigsaeure
has_related_synonym: 4-(2-Thienylketo)-2,3-dichlorophenoxyacetic acid
inchikey: AGHANLSBXUWXTB-UHFFFAOYSA-N
definition: An aromatic ketone that is 2,3-dichlorophenoxyacetic acid in which the hydrogen at position 4 on the benzene ring is replaced by a thiophenecarbonyl group. A loop diuretic used to treat hypertension, it was withdrawn from the market in 1982 due to links with hepatitis.
formula: C13H8Cl2O4S
database_cross_reference: CAS:40180-04-9
id: CHEBI:9590
database_cross_reference: DrugBank:DB04831
database_cross_reference: Drug_Central:2658
inchi: InChI=1S/C13H8Cl2O4S/c14-11-7(13(18)9-2-1-5-20-9)3-4-8(12(11)15)19-6-10(16)17/h1-5H,6H2,(H,16,17)
database_cross_reference: KEGG:C11702
database_cross_reference: KEGG:D02386
database_cross_reference: LINCS:LSM-5478
smiles: OC(=O)COc1ccc(C(=O)c2cccs2)c(Cl)c1Cl
database_cross_reference: PMID:22462724
database_cross_reference: PMID:23013248
database_cross_reference: PMID:24575896
database_cross_reference: PMID:2714684
database_cross_reference: PMID:41229
database_cross_reference: PMID:471149
database_cross_reference: PMID:471154
database_cross_reference: PMID:504040
database_cross_reference: PMID:6996137
database_cross_reference: PMID:7004678
database_cross_reference: PMID:7074982
database_cross_reference: PMID:7128663
database_cross_reference: PMID:7398677
database_cross_reference: PMID:8823314
database_cross_reference: PMID:913063
database_cross_reference: Reaxys:1260086
has_related_synonym: Thienylic acid
has_related_synonym: Ticrynafen
database_cross_reference: Wikipedia:Tienilic_acid
has_exact_synonym: [2,3-dichloro-4-(2-thienylcarbonyl)phenoxy]acetic acid
has_related_synonym: acide tienilique
has_related_synonym: acido tienilico
has_related_synonym: acidum tienilicum
has_obo_namespace: chebi_ontology
has_related_synonym: tienilic acid
in_subset: 3 STAR
imported from: chebi.owl