imported from
EC 5.4.99.7 (lanosterol synthase) inhibitor
An EC 5.4.99.* (intramolecular transferase transferring other groups) inhibitor that interferes with the action of lanosterol synthase (EC 5.4.99.7).
EC 5.4.99.* (intramolecular transferase transferring other groups) inhibitor
An EC 5.4.* (intramolecular transferase) inhibitor that interferes with the activity of any intramolecular transferase transferring other groups (EC 5.4.99.*).
EC 5.4.99.* (intramolecular transferase transferring other groups) inhibitors
inhibitor of intramolecular transferase transferring other groups
inhibitors of intramolecular transferase transferring other groups
intramolecular transferase transferring other groups inhibitor
intramolecular transferase transferring other groups inhibitors
A pyrimidine 2',3'-dideoxyribonucleoside compound having a 3'-azido substituent and thymine as the nucleobase.
EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitor
An EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor that interferes with the action of hypoxia-inducible factor-proline dioxygenase (EC 1.14.11.29).
EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitors
hypoxia-inducible factor-L-proline, 2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) inhibitor
hypoxia-inducible factor-L-proline, 2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) inhibitors
EC 2.6.1.40 [(R)-3-amino-2-methylpropionate--pyruvate transaminase] inhibitor
(R)-3-amino-2-methylpropanoate:pyruvate aminotransferase inhibitor
(R)-3-amino-2-methylpropanoate:pyruvate aminotransferase inhibitors
(R)-3-amino-2-methylpropionate transaminase inhibitor
(R)-3-amino-2-methylpropionate transaminase inhibitors
(R)-3-amino-2-methylpropionate--pyruvate aminotransferase inhibitor
(R)-3-amino-2-methylpropionate--pyruvate aminotransferase inhibitors
An EC 2.6.1.* (transaminase) inhibitor that interferes with the action of (R)-3-amino-2-methylpropionate--pyruvate transaminase (EC 2.6.1.40).
D-3-aminoisobutyrate--pyruvate aminotransferase inhibitor
D-3-aminoisobutyrate--pyruvate aminotransferase inhibitors
D-3-aminoisobutyrate--pyruvate transaminase inhibitor
D-3-aminoisobutyrate--pyruvate transaminase inhibitors
D-3-aminoisobutyrate-pyruvate aminotransferase inhibitor
D-3-aminoisobutyrate-pyruvate aminotransferase inhibitors
D-3-aminoisobutyrate-pyruvate transaminase inhibitor
D-3-aminoisobutyrate-pyruvate transaminase inhibitors
D-beta-aminoisobutyrate:pyruvate aminotransferase inhibitor
D-beta-aminoisobutyrate:pyruvate aminotransferase inhibitors
EC 2.6.1.40 [(R)-3-amino-2-methylpropionate--pyruvate transaminase] inhibitors
beta-aminoisobutyrate--pyruvate aminotransferase inhibitor
beta-aminoisobutyrate--pyruvate aminotransferase inhibitors
beta-aminoisobutyrate--pyruvate transaminase inhibitor
beta-aminoisobutyrate--pyruvate transaminase inhibitors
beta-aminoisobutyrate-pyruvate aminotransferase inhibitor
beta-aminoisobutyrate-pyruvate aminotransferase inhibitors
EC 2.1.1.8 (histamine N-methyltransferase) inhibitor
An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of histamine N-methyltransferase (EC 2.1.1.8).
EC 2.1.1.8 (histamine N-methyltransferase) inhibitors
S-adenosyl-L-methionine:histamine N-tele-methyltransferase inhibitor
S-adenosyl-L-methionine:histamine N-tele-methyltransferase inhibitors
S-adenosylmethionine-histamine N-methyltransferase inhibitor
S-adenosylmethionine-histamine N-methyltransferase inhibitors
histamine 1-methyltransferase inhibitors
An antagonist that interferes with the action of the calcium-binding messenger protein calmodulin.
An antagonist that binds to and deactivates IP3 receptors.
D-myo-inositol 1,4,5-trisphosphate receptor antagonist
D-myo-inositol 1,4,5-trisphosphate receptor antagonists
inositol trisphosphate receptor antagonist
inositol trisphosphate receptor antagonists
A substance that activates any of the Wnt signalling pathway, a group of signal transduction pathways made of proteins that pass signals from outside of a cell through cell surface receptors to the inside of the cell.
An agonist that binds to and activates formyl peptide receptors.
EC 1.14.99.66 (lysine-specific histone demethylase 1A) inhibitor
An EC 1.14.99.* (miscellaneous oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of lysine-specific histone demethylase 1A (EC 1.14.99.66).
EC 1.14.99.66 (lysine-specific histone demethylase 1A) inhibitors
[histone H3]-dimethyl-L-lysine(4)FAD-dependent demethylase 1A inhibitor
[histone H3]-dimethyl-L-lysine(4)FAD-dependent demethylase 1A inhibitors
amine oxidase (flavin containing) domain 2 inhibitor
amine oxidase (flavin containing) domain 2 inhibitors
lysine (K)-specific demethylase 1A inhibitor
lysine (K)-specific demethylase 1A inhibitors
lysine-specific demethylase 1A inhibitor
lysine-specific demethylase 1A inhibitors
lysine-specific histone demethylase 1A inhibitor
lysine-specific histone demethylase 1A inhibitors
Any compound that inhibits one or more steps in the pathway leading to the synthesis of hyaluronic acid.
Any bacterial metabolite produced during a metabolic reaction in Mycoplasma genitalium.
Any compound that inhibits the biosynthesis of teichoic acid.
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor
A DNA polymerase inhibitor that interferes with the action of a DNA-directed DNA polymerase (EC 2.7.7.7).
DNA nucleotidyltransferase (DNA-directed) inhibitor
DNA nucleotidyltransferase (DNA-directed) inhibitors
DNA-directed DNA polymerase (EC 2.7.7.7) inhibitor
DNA-directed DNA polymerase (EC 2.7.7.7) inhibitors
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitors
deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) inhibitor
deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) inhibitors
deoxyribonucleate nucleotidyltransferase inhibitor
deoxyribonucleate nucleotidyltransferase inhibitors
deoxyribonucleic acid duplicase inhibitor
deoxyribonucleic acid duplicase inhibitors
deoxyribonucleic acid polymerase inhibitor
deoxyribonucleic acid polymerase inhibitors
deoxyribonucleic polymerase I inhibitors
EC 2.7.11.20 (elongation factor 2 kinase) inhibitor
ATP:[elongation factor 2] phosphotransferase inhibitor
ATP:[elongation factor 2] phosphotransferase inhibitors
Any EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of elongation factor 2 kinase (EC 2.7.11.20).
EC 2.7.11.20 (elongation factor 2 kinase) inhibitors
calmodulin-dependent protein kinase III inhibitor
calmodulin-dependent protein kinase III inhibitors
elongation factor 2 kinase (EC 2.7.11.20) inhibitor
elongation factor 2 kinase (EC 2.7.11.20) inhibitors
EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor
A EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of channel-conductance-controlling ATPase (EC 3.6.3.49, also known as cystic fibrosis conductance regulator, CFCR).
ATP phosphohydrolase (channel-conductance-controlling) inhibitor
ATP phosphohydrolase (channel-conductance-controlling) inhibitors
EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitors
channel-conductance-controlling ATPase (EC 3.6.3.49) inhibitor
channel-conductance-controlling ATPase (EC 3.6.3.49) inhibitors
channel-conductance-controlling ATPase inhibitor
channel-conductance-controlling ATPase inhibitors
cystic fibrosis conductance regulator inhibitor
cystic fibrosis conductance regulator inhibitors
cystic fibrosis transmembrane conductance regulator inhibitor
cystic fibrosis transmembrane conductance regulator inhibitors
cystic-fibrosis membrane-conductance-regulating protein inhibitor
cystic-fibrosis membrane-conductance-regulating protein inhibitors
An antagonist that binds to and deactivates the dopamine receptor D2, the main receptor for all antipsychotic drugs.
An inhibitor that interferes with RUNX1 (runt-related transcription factor 1), a transcription factor protein that regulates the differentiation of haematopoietic stem cells into mature blood cells.
acute myeloid leukemia 1 protein inhibitor
acute myeloid leukemia 1 protein inhibitors
core-binding factor subunit alpha-2 inhibitor
core-binding factor subunit alpha-2 inhibitors
core-binding factor subunit alpha2 inhibitor
core-binding factor subunit alpha2 inhibitors
runt-related transcription factor 1 inhibitor
runt-related transcription factor 1 inhibitors
An antagonist that binds to and deactivates melatonin receptors.
An inhibitor of gene expression of human immunodeficiency virus type 1 (HIV-1) at the transcriptional level through interference with Tat-mediated transactivation.
HIV-1 trans-activator of transcription antagonist
HIV-1 trans-activator of transcription antagonists
human immunodeficiency virus type 1 Tat antagonist
human immunodeficiency virus type 1 Tat antagonists
human immunodeficiency virus type 1 Tat inhibitor
human immunodeficiency virus type 1 Tat inhibitors
human immunodeficiency virus type 1 trans-activator of transcription antagonist
human immunodeficiency virus type 1 trans-activator of transcription antagonists
EC 2.7.11.17 (Ca(2+)/calmodulin-dependent protein kinase) inhibitor
ATP:caldesmon O-phosphotransferase inhibitor
ATP:caldesmon O-phosphotransferase inhibitors
ATP:protein phosphotransferase ((2+)/calmodulin-dependent) inhibitor
ATP:protein phosphotransferase ((2+)/calmodulin-dependent) inhibitors
Any EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of a Ca(2+)/calmodulin-dependent protein kinase (EC 2.7.11.17).
Ca(2+)/calmodulin-dependent microtubule-associated protein 2 kinase inhibitor
Ca(2+)/calmodulin-dependent microtubule-associated protein 2 kinase inhibitors
Ca(2+)/calmodulin-dependent protein kinase (EC 2.7.11.17) inhibitor
Ca(2+)/calmodulin-dependent protein kinase (EC 2.7.11.17) inhibitors
Ca(2+)/calmodulin-dependent protein kinase 1 inhibitor
Ca(2+)/calmodulin-dependent protein kinase 1 inhibitors
Ca(2+)/calmodulin-dependent protein kinase II inhibitor
Ca(2+)/calmodulin-dependent protein kinase II inhibitors
Ca(2+)/calmodulin-dependent protein kinase IV inhibitor
Ca(2+)/calmodulin-dependent protein kinase IV inhibitors
Ca(2+)/calmodulin-dependent protein kinase inhibitor
Ca(2+)/calmodulin-dependent protein kinase inhibitors
Ca(2+)/calmodulin-dependent protein kinase kinase beta inhibitor
Ca(2+)/calmodulin-dependent protein kinase kinase beta inhibitors
Ca(2+)/calmodulin-dependent protein kinase kinase inhibitor
Ca(2+)/calmodulin-dependent protein kinase kinase inhibitors
CaM-regulated serine/threonine kinase inhibitor
CaM-regulated serine/threonine kinase inhibitors
EC 2.7.11.17 (Ca(2+)/calmodulin-dependent protein kinase) inhibitors
caldesmon kinase (phosphorylating) inhibitor
caldesmon kinase (phosphorylating) inhibitors
calmodulin-dependent kinase II inhibitor
calmodulin-dependent kinase II inhibitors
microtubule-associated protein 2 kinase inhibitor
microtubule-associated protein 2 kinase inhibitors
A dopamine agonist that binds to and activates the dopamine receptor D1.
An agonist that enhances the action of smoothened (SMO) receptor.
EC 1.14.11.1 (gamma-butyrobetaine dioxygenase) inhibitor
4-trimethylammoniobutanoate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) inhibitor
4-trimethylammoniobutanoate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) inhibitors
An EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor that interferes with the action of gamma-butyrobetaine dioxygenase (EC 1.14.11.1).
EC 1.14.11.1 (gamma-butyrobetaine dioxygenase) inhibitors
alpha-butyrobetaine hydroxylase inhibitor
alpha-butyrobetaine hydroxylase inhibitors
gamma-butyrobetaine hydroxylase inhibitor
gamma-butyrobetaine hydroxylase inhibitors
EC 1.13.11.11 (tryptophan 2,3-dioxygenase) inhibitor
An EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitor that interferes with the action of tryptophan 2,3-dioxygenase (EC 1.13.11.11).
EC 1.13.11.11 (tryptophan 2,3-dioxygenase) inhibitors
L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing) inhibitor
L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing) inhibitors
L-tryptophan:oxygen 2,3-oxidoreductase (ring-opening) inhibitor
L-tryptophan:oxygen 2,3-oxidoreductase (ring-opening) inhibitors
tryptophan 2,3-dioxygenase (EC 1.13.11.11) inhibitor
tryptophan 2,3-dioxygenase (EC 1.13.11.11) inhibitors
A compound used with herbicides that reduces the effect of the herbicide on crop plants or otherwise improves the selectivity of the herbicide for weed species over the crop plant.
EC 1.14.11.2 (procollagen-proline dioxygenase) inhibitor
An EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor that interferes with the action of procollagen-proline dioxygenase (EC 1.14.11.2).
EC 1.14.11.2 (procollagen-proline dioxygenase) inhibitors
hydroxylase, collagen proline inhibitors
procollagen-L-proline,2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) inhibitor
procollagen-L-proline,2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) inhibitors
procollagen-proline 4-dioxygenase inhibitor
procollagen-proline 4-dioxygenase inhibitors
procollagen-proline dioxygenase (EC 1.14.11.2) inhibitor
procollagen-proline dioxygenase (EC 1.14.11.2) inhibitors
procollagen-proline dioxygenase inhibitor
procollagen-proline dioxygenase inhibitors
procollagen-proline,2-oxoglutarate-4-dioxygenase inhibitor
procollagen-proline,2-oxoglutarate-4-dioxygenase inhibitors
proline protocollagen hydroxylase inhibitor
proline protocollagen hydroxylase inhibitors
proline, 2-oxoglutarate dioxygenase inhibitor
proline, 2-oxoglutarate dioxygenase inhibitors
proline,2-oxoglutarate 4-dioxygenase inhibitor
proline,2-oxoglutarate 4-dioxygenase inhibitors
prolyl-glycyl-peptide, 2-oxoglutarate:oxygen oxidoreductase, 4-hydroxylating inhibitor
prolyl-glycyl-peptide, 2-oxoglutarate:oxygen oxidoreductase, 4-hydroxylating inhibitors
prolylprotocollagen dioxygenase inhibitor
prolylprotocollagen dioxygenase inhibitors
prolylprotocollagen hydroxylase inhibitor
prolylprotocollagen hydroxylase inhibitors
protocollagen proline 4-hydroxylase inhibitor
protocollagen proline 4-hydroxylase inhibitors
protocollagen proline dioxygenase inhibitor
protocollagen proline dioxygenase inhibitors
protocollagen proline hydroxylase inhibitor
protocollagen proline hydroxylase inhibitors
protocollagen prolyl hydroxylase inhibitor
protocollagen prolyl hydroxylase inhibitors
EC 3.2.1.23 (beta-galactosidase) inhibitor
An EC 3.2.1.* (glycosidase) inhibitor that interferes with the action of beta-galactosidase (EC 3.2.1.23).
EC 3.2.1.23 (beta-galactosidase) inhibitors
beta-D-galactoside galactohydrolase inhibitor
beta-D-galactoside galactohydrolase inhibitors
exo-(1->4)-beta-D-galactanase inhibitors
An inhibitor of transient receptor potential cation channel subfamily M member 4.
Transient receptor potential cation channel subfamily M member 4 inhibitor
Transient receptor potential cation channel subfamily M member 4 inhibitors
An antigen that is found in more than one species.
A reagent that lightens or whitens a substrate through chemical reaction. Bleaching reactions usually involve oxidative or reductive processes that degrade colour systems. Bleaching can occur by destroying one or more of the double bonds in the conjugated chain, by cleaving the conjugated chain, or by oxidation of one of the other moieties in the conjugated chain. Their reactivity results in many bleaches having strong bactericidal, disinfecting, and sterilising properties.
EC 3.6.5.* (hydrolases acting on GTP; involved in cellular and subcellular movement) inhibitor
Any EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor that interferes with the action of any such enzyme acting on GTP that is involved in cellular and subcellular movement (EC 3.6.5.*).
EC 3.6.5.* (hydrolases acting on GTP; involved in cellular and subcellular movement) inhibitors
An EC 3.6.5.* (hydrolases acting on GTP; involved in cellular and subcellular movement) inhibitor that interferes with the action of dynamin GTPase (EC 3.6.5.5).
GTP phosphohydrolase (vesicle-releasing) inhibitor
GTP phosphohydrolase (vesicle-releasing) inhibitors
An agonist that binds to and activates farnesoid X receptors
A drug that makes increases the sensitivity of tumour cells to radiation therapy.
5-hydroxytryptamine 2A receptor inverse agonist
5-hydroxytryptamine (2A) receptor inverse agonist
5-hydroxytryptamine (2A) receptor inverse agonists
5-hydroxytryptamine 2A receptor inverse agonists
An inverse agonist that binds to the same receptor as a 5-hydroxytryptamine 2A receptor agonist, but which induces a pharmacological response opposite to that agonist.
Any inhibitor of B-cell lymphoma 2 protein.
lymphocyte function-associated antigen-1 antagonist
Any antagonist of lymphocyte function-associated antigen-1
lymphocyte function-associated antigen-1 antagonists
A plant growth regulator that produces male sterility in plants by preventing pollen development, pollen shed, or pollen viability. This makes the plant adaptable to hybridization without the need for laborious hand pollination.
A compound that inhibits the oxidation of any fatty acid.
EC 2.4.1.17 (glucuronosyltransferase) inhibitor
1-naphthol glucuronyltransferase inhibitor
1-naphthol glucuronyltransferase inhibitors
1-naphthol-UDP-glucuronosyltransferase inhibitor
1-naphthol-UDP-glucuronosyltransferase inhibitors
17beta-hydroxysteroid UDP-glucuronosyltransferase inhibitor
17beta-hydroxysteroid UDP-glucuronosyltransferase inhibitors
3alpha-hydroxysteroid UDP-glucuronosyltransferase inhibitor
3alpha-hydroxysteroid UDP-glucuronosyltransferase inhibitors
4-hydroxybiphenyl UDP-glucuronosyltransferase inhibitor
4-hydroxybiphenyl UDP-glucuronosyltransferase inhibitors
A EC 2.4.1.* (hexosyltransferase) inhibitor that inhibits the action of glucuronosyltransferase (EC 2.4.1.17).
EC 2.4.1.17 (glucuronosyltransferase) inhibitors
UDP glucuronic acid transferase inhibitors
UDP-alpha-D-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific; conformation-inverting) inhibitor
UDP-alpha-D-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific; conformation-inverting) inhibitors
UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) inhibitor
UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) inhibitors
uridine 5'-diphosphoglucuronyltransferase inhibitor
uridine 5'-diphosphoglucuronyltransferase inhibitors
uridine diphosphate glucuronyltransferase inhibitor
uridine diphosphate glucuronyltransferase inhibitors
uridine diphosphoglucuronosyltransferase inhibitor
uridine diphosphoglucuronosyltransferase inhibitors
uridine diphosphoglucuronyltransferase inhibitor
uridine diphosphoglucuronyltransferase inhibitors
An antagonist that binds to and deactivates neuropeptide Y receptors.
Any protein kinase inhibitor that interferes with the action of salt-inducible kinase 2.
serine/threonine-protein kinase SIK2 inhibitor
EC 2.5.1.46 (deoxyhypusine synthase) inhibitor
(4-aminobutyl)lysine synthase inhibitors
An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of deoxyhypusine synthase (EC 2.5.1.46).
EC 2.5.1.46 (deoxyhypusine synthase) inhibitors
[eIF-5A]-deoxyhypusine synthase inhibitor
[eIF-5A]-deoxyhypusine synthase inhibitors
[eIF5A-precursor]-lysine:spermidine 4-aminobutyltransferase (propane-1,3-diamine-forming) inhibitor
[eIF5A-precursor]-lysine:spermidine 4-aminobutyltransferase (propane-1,3-diamine-forming) inhibitors
spermidine:eIF5A-lysine 4-aminobutyltransferase (propane-1,3-diamine-forming) inhibitor
spermidine:eIF5A-lysine 4-aminobutyltransferase (propane-1,3-diamine-forming) inhibitors
hypoxia-inducible factor pathway activator
An activator that activates the hypoxia inducible factor (HIF) pathway.
hypoxia-inducible factor pathway activators
EC 1.15.1.1 (superoxide dismutase) inhibitor
lipopolysaccharide biosynthesis inhibitor
Any compound that inhibits the biosynthesis of any lipopolysaccharide.
lipopolysaccharide biosynthesis inhibitors
EC 3.5.1.108 (UDP-3-O-acyl-N-acetylglucosamine deacetylase) inhibitor
An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of UDP-3-O-acyl-N-acetylglucosamine deacetylase (EC 3.5.1.108).
EC 3.5.1.108 (UDP-3-O-acyl-N-acetylglucosamine deacetylase) inhibitors
UDP-(3-O-(R-3-hydroxymyristoyl))-N-acetylglucosamine deacetylase inhibitor
UDP-(3-O-(R-3-hydroxymyristoyl))-N-acetylglucosamine deacetylase inhibitors
UDP-(3-O-acyl)-N-acetylglucosamine deacetylase inhibitor
UDP-(3-O-acyl)-N-acetylglucosamine deacetylase inhibitors
UDP-3-O-((R)-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase inhibitor
UDP-3-O-((R)-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase inhibitors
UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase inhibitor
UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase inhibitors
UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetyl-alpha-D-glucosamine amidohydrolase inhibitor
UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetyl-alpha-D-glucosamine amidohydrolase inhibitors
UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetylglucosamine amidohydrolase inhibitor
UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetylglucosamine amidohydrolase inhibitors
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase inhibitor
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase inhibitors
UDP-3-O-acyl-GlcNAc deacetylase inhibitor
UDP-3-O-acyl-GlcNAc deacetylase inhibitors
A role borne by a molecule that acts to counteract or neutralise the deleterious effects of barbiturates.
platelet-activating factor receptor antagonist
An antagonist that acts at the platelet-activating factor receptor.
platelet-activating factor receptor antagonists
EC 1.8.1.4 (dihydrolipoyl dehydrogenase) inhibitor
An EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of dihydrolipoyl dehydrogenase (EC 1.8.1.4).
E3 component of alpha-ketoacid dehydrogenase complexes inhibitor
E3 component of alpha-ketoacid dehydrogenase complexes inhibitors
EC 1.8.1.4 (dihydrolipoyl dehydrogenase) inhibitors
dihydrolipoamide dehydrogenase inhibitor
dihydrolipoamide dehydrogenase inhibitors
dihydrolipoamide:NAD(+) oxidoreductase inhibitor
dihydrolipoamide:NAD(+) oxidoreductase inhibitors
dihydrothioctic dehydrogenase inhibitors
glycine-cleavage system L-protein inhibitor
glycine-cleavage system L-protein inhibitors
lipoamide dehydrogenase (NADH) inhibitor
lipoamide dehydrogenase (NADH) inhibitors
lipoamide oxidoreductase (NADH) inhibitor
lipoamide oxidoreductase (NADH) inhibitors
protein-6-N-(dihydrolipoyl)lysine:NAD(+) oxidoreductase inhibitor
protein-6-N-(dihydrolipoyl)lysine:NAD(+) oxidoreductase inhibitors
protein-N(6)-(dihydrolipoyl)lysine:NAD(+) oxidoreductase inhibitor
protein-N(6)-(dihydrolipoyl)lysine:NAD(+) oxidoreductase inhibitors
EC 2.4.2.8 (hypoxanthine phosphoribosyltransferase) inhibitor
6-hydroxypurine phosphoribosyltransferase inhibitor
6-mercaptopurine phosphoribosyltransferase inhibitor
An EC 2.4.2.* (pentosyltransferase) inhibitor that interferes with the action of hypoxanthine phosphoribosyltransferase (EC 2.4.2.8).
EC 2.4.2.8 (hypoxanthine phosphoribosyltransferase) inhibitors
IMP:diphosphate phospho-D-ribosyltransferase inhibitor
guanine phosphoribosyltransferase inhibitor
guanine-hypoxanthine phosphoribosyltransferase inhibitor
guanosine 5'-phosphate pyrophosphorylase inhibitor
guanosine phosphoribosyltransferase inhibitor
hypoxanthine phosphoribosyltransferase (EC 2.4.2.8) inhibitor
hypoxanthine phosphoribosyltransferase (EC 2.4.2.8) inhibitors
hypoxanthine phosphoribosyltransferase inhibitor
hypoxanthine phosphoribosyltransferase inhibitors
hypoxanthine-guanine phosphoribosyltransferase inhibitor
inosine 5'-phosphate pyrophosphorylas inhibitore
inosinic acid pyrophosphorylase inhibitor
purine-6-thiol phosphoribosyltransferase inhibitor
An inhibitor of peroxidases (EC 1.11.1.*) that inhibits the action of peroxidase (EC 1.11.1.7).
Arthromyces ramosus peroxidase inhibitor
Arthromyces ramosus peroxidase inhibitors
phenolic donor:hydrogen-peroxide oxidoreductase inhibitor
phenolic donor:hydrogen-peroxide oxidoreductase inhibitors
An antagonist that acts at the liver receptor homologue-1.
nuclear receptor subfamily 5 group A member 2 antagonist
nuclear receptor subfamily 5 group A member 2 antagonists
A prodrug that, on administration, undergoes chemical conversion by biochemical (enzymatic), chemical (possibly following an enzymatic step), or physical (e.g. photochemical) activation processes before becoming the pharmacologically active pesticide for which it is a propesticide.
A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active insecticide for which it is a proinsecticide.
A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active fungicide for which it is a profungicide.
A compound that, on administration, must undergo chemical conversion by biochemical (enzymatic), chemical (possibly following an enzymatic step), or physical (e.g. photochemical) activation processes before becoming the pharmacologically active herbicide for which it is a proherbicide.
A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active insecticide for which it is a proacaricide.
A compound that, on administration, must undergo chemical conversion by biochemical (enzymatic), chemical (possibly following an enzymatic step), or physical (e.g. photochemical) activation processes before becoming the pharmacologically active herbicide savener for which it is a prosafener.
S100 calcium-binding protein B inhibitor
Any inhibitor of S100 calcium-binding protein B.
S100 calcium-binding protein B inhibitors
A compound that, on administration, undergoes conversion by biochemical (enzymatic), chemical (possibly following an enzymatic step), or physical (e.g. photochemical) activation processes before becoming the active agent for which it is a pro-agent.
A role borne by a molecule that acts to counteract or neutralise the nerve agent sarin.
EC 4.4.1.14 (1-aminocyclopropane-1-carboxylate synthase) inhibitor
1-aminocyclopropane-1-carboxylate synthase inhibitor
1-aminocyclopropane-1-carboxylate synthase inhibitors
1-aminocyclopropane-1-carboxylate synthetase inhibitor
1-aminocyclopropane-1-carboxylate synthetase inhibitors
1-aminocyclopropane-1-carboxylic acid synthase inhibitor
1-aminocyclopropane-1-carboxylic acid synthase inhibitors
1-aminocyclopropanecarboxylate synthase inhibitor
1-aminocyclopropanecarboxylate synthase inhibitors
An EC 4.4.1.* (C-S lyase) inhibitor that interferes with the action of 1-aminocyclopropane-1-carboxylate synthase (EC 4.4.1.14).
EC 4.4.1.14 (1-aminocyclopropane-1-carboxylate synthase) inhibitors
S-adenosyl-L-methionine methylthioadenosine-lyase (1-aminocyclopropane-1-carboxylate-forming) inhibitor
S-adenosyl-L-methionine methylthioadenosine-lyase (1-aminocyclopropane-1-carboxylate-forming) inhibitors
S-adenosyl-L-methionine methylthioadenosine-lyase inhibitor
S-adenosyl-L-methionine methylthioadenosine-lyase inhibitors
aminocyclopropanecarboxylate synthase inhibitor
aminocyclopropanecarboxylate synthase inhibitors
aminocyclopropanecarboxylic acid synthase inhibitor
aminocyclopropanecarboxylic acid synthase inhibitors
eukaryotic initiation factor 4F inhibitor
Any compound that inihibits the mammalian protein, eukaryotic initiation factor 4F.
eukaryotic initiation factor 4F inhibitors
bromodomain-containing protein 4 inhibitor
Any inhibitor of bromodomain-containing protein 4 (BRD4).
bromodomain-containing protein 4 inhibitors
EC 2.7.11.30 (receptor protein serine/threonine kinase) inhibitor
ATP:[receptor-protein] phosphotransferase inhibitor
ATP:[receptor-protein] phosphotransferase inhibitors
An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the activity of receptor protein serine/threonine kinase (EC 2.7.11.30).
EC 2.7.11.30 (receptor protein serine/threonine kinase) inhibitors
inhibitor of receptor protein serine/threonine kinase
receptor protein serine/threonine kinase (EC 2.7.11.30) inhibitor
receptor protein serine/threonine kinase (EC 2.7.11.30) inhibitors
receptor protein serine/threonine kinase inhibitor
receptor protein serine/threonine kinase inhibitors
receptor serine/threonine protein kinase inhibitor
receptor serine/threonine protein kinase inhibitors
receptor type I serine/threonine protein kinase inhibitor
receptor type I serine/threonine protein kinase inhibitors
receptor type II serine/threonine protein kinase inhibitor
receptor type II serine/threonine protein kinase inhibitors
An agonist that binds to and activates capsaicin receptors
transient receptor potential cation channel subfamily V member 1 agonist
transient receptor potential cation channel subfamily V member 1 agonists
A cardiovascular drug that tends to raise reduced blood pressure.
An agonist at the transient receptor potential cation channel A1 (TRPA1).
transient receptor potential ankyrin 1 agonist
transient receptor potential ankyrin 1 agonists
transient receptor potential cation channel A1 agonist
transient receptor potential cation channel A1 agonists
EC 2.5.1.48 (cystathionine gamma-synthase) inhibitor
4-O-succinyl-L-homoserine:L-cysteine S-(3-amino-3-carboxypropyl)transferase inhibitor
4-O-succinyl-L-homoserine:L-cysteine S-(3-amino-3-carboxypropyl)transferase inhibitors
An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of cystathionine gamma-synthase (EC 2.5.1.48).
EC 2.5.1.48 (cystathionine gamma-synthase) inhibitors
O(4)-succinyl-L-homoserine:L-cysteine S-(3-amino-3-carboxypropyl)transferase inhibitor
O(4)-succinyl-L-homoserine:L-cysteine S-(3-amino-3-carboxypropyl)transferase inhibitors
O-succinyl-L-homoserine succinate-lyase (adding cysteine) inhibitor
O-succinyl-L-homoserine succinate-lyase (adding cysteine) inhibitors
O-succinylhomoserine (thiol)-lyase inhibitor
O-succinylhomoserine (thiol)-lyase inhibitors
O-succinylhomoserine synthase inhibitors
O-succinylhomoserine synthetase inhibitor
O-succinylhomoserine synthetase inhibitors
homoserine O-transsuccinylase inhibitors
EC 1.1.1.146 (11beta-hydroxysteroid dehydrogenase) inhibitor
11beta-hydroxy steroid dehydrogenase inhibitor
11beta-hydroxy steroid dehydrogenase inhibitors
11beta-hydroxysteroid dehydrogenase inhibitor
11beta-hydroxysteroid dehydrogenase inhibitors
11beta-hydroxysteroid dehydrogenase type 1 inhibitor
11beta-hydroxysteroid dehydrogenase type 1 inhibitors
11beta-hydroxysteroid:NADP(+) 11-oxidoreductase inhibitor
11beta-hydroxysteroid:NADP(+) 11-oxidoreductase inhibitors
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of 11beta-hydroxysteroid dehydrogenase (EC 1.1.1.146).
EC 1.1.1.146 (11beta-hydroxysteroid dehydrogenase) inhibitors
beta-hydroxysteroid dehydrogenase inhibitor
beta-hydroxysteroid dehydrogenase inhibitors
corticosteroid 11beta-dehydrogenase inhibitor
corticosteroid 11beta-dehydrogenase inhibitors
dehydrogenase, 11beta-hydroxy steroid inhibitor
dehydrogenase, 11beta-hydroxy steroid inhibitors
Any mammalian metabolite produced during a metabolic reaction in Papio hamadryas.
Any psychotropic drug that induces anxiety or panic.
An EC 3.4.22.* (cysteine endopeptidase) inhibitor that interferes with the action of caspase-3 (EC 3.4.22.56).
Any compound that can disrupt the functions of the endocrine (hormone) system
ATPase motor cytoplasmic dynein inhibitor
ATPase motor cytoplasmic dynein inhibitors
Any inhibitor of ATPase motor cytoplasmic dynein.
A Bronsted acid derived from one or more inorganic compounds. Inorganic acids (also known as mineral acids) form hydrons and conjugate base ions when dissolved in water.
Any pathway inhibitor that acts on the carotenoid biosynthesis pathway.
Any inhibitor that interferes with the action of the protein RhoA.
Ras homolog gene family, member A inhibitor
Ras homolog gene family, member A inhibitors
Any inhibitor that interferes with the action of the protein RhoC.
Ras homolog gene family, member C inhibitor
Ras homolog gene family, member C inhibitors
EC 1.1.1.159 (7alpha-hydroxysteroid dehydrogenase) inhibitor
7alpha-hydroxy steroid dehydrogenase inhibitor
7alpha-hydroxy steroid dehydrogenase inhibitors
7alpha-hydroxysteroid dehydrogenase inhibitor
7alpha-hydroxysteroid dehydrogenase inhibitors
7alpha-hydroxysteroid:NAD+ 7-oxidoreductase inhibitor
7alpha-hydroxysteroid:NAD+ 7-oxidoreductase inhibitors
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD+ or NADP+ acceptor) inhibitor that interferes with the action of 7alpha-hydroxysteroid dehydrogenase (EC 1.1.1.159).
EC 1.1.1.159 (7alpha-hydroxysteroid dehydrogenase) inhibitors
A hormone antagonist that acts at angiotensin receptors.
Any compound that induces the process of autophagy (the self-digestion of one or more components of a cell through the action of enzymes originating within the same cell).
An antagonist that binds to and blocks the activity of prostaglandin receptors.
EC 6.3.5.* (carbon-nitrogen ligases with glutamine as amido-N-donor) inhibitor
An EC 6.3.* (C-N bond-forming ligase) inhibitor that interferes with the action of any carbon-nitrogen ligases with glutamine as amido-N-donor (EC 6.3.5.*).
EC 6.3.5.* (carbon-nitrogen ligases with glutamine as amido-N-donor) inhibitors
EC 6.3.5.5 [carbamoyl-phosphate synthase (glutamine-hydrolysing)] inhibitor
An EC 6.3.5.* (carbon-nitrogen ligases with glutamine as amido-N-donor) inhibitor that interferes with the action of carbamoyl-phosphate synthase (glutamine-hydrolysing) (EC 6.3.5.5).
EC 6.3.5.5 [carbamoyl-phosphate synthase (glutamine-hydrolysing)] inhibitors
HCO3(-):L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) inhibitor
HCO3(-):L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) inhibitors
carbamoyl phosphate synthetase inhibitor
carbamoyl phosphate synthetase inhibitors
carbamoyl-phosphate synthase (glutamine-hydrolysing) (EC 6.3.5.5) inhibitor
carbamoyl-phosphate synthase (glutamine-hydrolysing) (EC 6.3.5.5) inhibitors
carbamoyl-phosphate synthetase (glutamine-hydrolysing) inhibitor
carbamoyl-phosphate synthetase (glutamine-hydrolysing) inhibitors
carbamoylphosphate synthetase II inhibitor
carbamoylphosphate synthetase II inhibitors
carbamyl phosphate synthetase (glutamine) inhibitor
carbamyl phosphate synthetase (glutamine) inhibitors
carbon-dioxide:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) inhibitor
carbon-dioxide:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) inhibitors
glutamine-dependent carbamoyl-phosphate synthase inhibitor
glutamine-dependent carbamoyl-phosphate synthase inhibitors
glutamine-dependent carbamyl phosphate synthetase inhibitor
glutamine-dependent carbamyl phosphate synthetase inhibitors
hydrogen-carbonate:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) inhibitor
hydrogen-carbonate:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) inhibitors
EC 6.3.4.* (other carbon--nitrogen ligases) inhibitor
Any EC 6.3.* (C-N bond-forming ligase) inhibitor that interferes with the action of 'other carbon--nitrogen ligases.
EC 6.3.4.* (other carbon--nitrogen ligases) inhibitors
EC 6.3.4.2 [CTP synthase (glutamine hydrolyzing)] inhibitor
Any EC 6.3.4.* (other carbon--nitrogen ligases) inhibitor that interferes with the action of CTP synthase (glutamine hydrolyzing) (EC 6.3.4.2).
CTP synthase (glutamine hydrolyzing) (EC6.3.4.2) inhibitor
CTP synthase (glutamine hydrolyzing) (EC6.3.4.2) inhibitors
CTP synthase (glutamine hydrolyzing) inhibitor
CTP synthase (glutamine hydrolyzing) inhibitors
EC 6.3.4.2 [CTP synthase (glutamine hydrolyzing)] inhibitors
UTP:L-glutamine amido-ligase (ADP-forming) inhibitor
UTP:L-glutamine amido-ligase (ADP-forming) inhibitors
cytidine triphosphate synthetase inhibitor
cytidine triphosphate synthetase inhibitors
EC 6.3.5.3 (phosphoribosylformylglycinamidine synthase) inhibitor
2-N-formyl-1-N-(5-phospho-D-ribosyl)glycinamide:L-glutamine amido-ligase (ADP-forming) inhibitor
2-N-formyl-1-N-(5-phospho-D-ribosyl)glycinamide:L-glutamine amido-ligase (ADP-forming) inhibitors
5'-phosphoribosylformylglycinamide:L-glutamine amido-ligase (ADP-forming) inhibitor
5'-phosphoribosylformylglycinamide:L-glutamine amido-ligase (ADP-forming) inhibitors
Any EC 6.3.5.* (carbon-nitrogen ligases with glutamine as amido-N-donor) inhibitor that interferes with the action of phosphoribosylformylglycinamidine synthase (EC 6.3.5.3).
EC 6.3.5.3 (phosphoribosylformylglycinamidine synthase) inhibitors
N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide:L-glutamine amido-ligase (ADP-forming) inhibitor
N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide:L-glutamine amido-ligase (ADP-forming) inhibitors
formylglycinamide ribonucloetide amidotransferase inhibitor
formylglycinamide ribonucloetide amidotransferase inhibitors
formylglycinamide ribotide amidotransferase inhibitor
formylglycinamide ribotide amidotransferase inhibitors
phosphoribosylformylglycinamidine synthase inhibitor
phosphoribosylformylglycinamidine synthase inhibitors
phosphoribosylformylglycinamidine synthetase inhibitor
phosphoribosylformylglycinamidine synthetase inhibitors
phosphoribosylformylglycineamidine synthetase inhibitor
phosphoribosylformylglycineamidine synthetase inhibitors
EC 6.3.5.2 [GMP synthase (glutamine-hydrolysing)] inhibitor
An EC 6.3.5.* (carbon-nitrogen ligases with glutamine as amido-N-donor) inhibitor that interferes with the action of GMP synthase (glutamine-hydrolysing) (EC 6.3.5.2).
EC 6.3.5.2 [GMP synthase (glutamine-hydrolysing)] inhibitors
GMP synthase (glutamine-hydrolysing) inhibitor
GMP synthase (glutamine-hydrolysing) inhibitors
GMP synthetase (glutamine-hydrolysing) inhibitor
GMP synthetase (glutamine-hydrolysing) inhibitors
guanosine 5'-monophosphate synthetase inhibitor
guanosine 5'-monophosphate synthetase inhibitors
guanosine monophosphate synthetase (glutamine-hydrolyzing) inhibitor
guanosine monophosphate synthetase (glutamine-hydrolyzing) inhibitors
guanylate synthetase (glutamine-hydrolyzing) inhibitor
guanylate synthetase (glutamine-hydrolyzing) inhibitors
xanthosine 5'-phosphate amidotransferase inhibitor
xanthosine 5'-phosphate amidotransferase inhibitors
xanthosine-5'-phosphate:L-glutamine amido-ligase (AMP-forming) inhibitor
xanthosine-5'-phosphate:L-glutamine amido-ligase (AMP-forming) inhibitors
An antagonist that acts on glutamine receptors.
EC 4.1.1.39 (ribulose-bisphosphate carboxylase) inhibitor
3-phospho-D-glycerate carboxy-lyase (dimerizing) inhibitor
3-phospho-D-glycerate carboxy-lyase (dimerizing) inhibitors
3-phospho-D-glycerate carboxy-lyase (dimerizing; D-ribulose-1,5-bisphosphate-forming) inhibitor
3-phospho-D-glycerate carboxy-lyase (dimerizing; D-ribulose-1,5-bisphosphate-forming) inhibitors
An EC 4.1.1.* (carboxy-lyase) inhibitor that interferes with the action of ribulose-bisphosphate carboxylase (EC 4.1.1.39).
D-ribulose 1,5-bisphosphate carboxylase inhibitor
D-ribulose 1,5-bisphosphate carboxylase inhibitors
D-ribulose 1,5-diphosphate carboxylase inhibitor
D-ribulose 1,5-diphosphate carboxylase inhibitors
EC 4.1.1.39 (ribulose-bisphosphate carboxylase) inhibitors
diphosphoribulose carboxylase inhibitors
ribulose 1,5-bisphosphate carboxylase inhibitor
ribulose 1,5-bisphosphate carboxylase inhibitors
ribulose 1,5-bisphosphate carboxylase/oxygenase inhibitor
ribulose 1,5-bisphosphate carboxylase/oxygenase inhibitors
ribulose 1,5-diphosphate carboxylase inhibitor
ribulose 1,5-diphosphate carboxylase inhibitors
ribulose 1,5-diphosphate carboxylase/oxygenase inhibitor
ribulose 1,5-diphosphate carboxylase/oxygenase inhibitors
ribulose bisphosphate carboxylase/oxygenase inhibitor
ribulose bisphosphate carboxylase/oxygenase inhibitors
ribulose diphosphate carboxylase inhibitor
ribulose diphosphate carboxylase inhibitors
ribulose diphosphate carboxylase/oxygenase inhibitor
ribulose diphosphate carboxylase/oxygenase inhibitors
ribulose-bisphosphate carboxylase inhibitor
ribulose-bisphosphate carboxylase inhibitors
EC 2.4.2.14 (amidophosphoribosyltransferase) inhibitor
5'-phosphoribosylpyrophosphate amidotransferase inhibitor
5'-phosphoribosylpyrophosphate amidotransferase inhibitors
5-phospho-beta-D-ribosylamine:diphosphate phospho-alpha-D-ribosyltransferase (glutamate-amidating) inhibitor
5-phospho-beta-D-ribosylamine:diphosphate phospho-alpha-D-ribosyltransferase (glutamate-amidating) inhibitors
5-phosphoribosyl-1-pyrophosphate amidotransferase inhibitor
5-phosphoribosyl-1-pyrophosphate amidotransferase inhibitors
5-phosphoribosylamine:diphosphate phospho-alpha-D-ribosyltransferase (glutamate-amidating) inhibitor
5-phosphoribosylamine:diphosphate phospho-alpha-D-ribosyltransferase (glutamate-amidating) inhibitors
5-phosphororibosyl-1-pyrophosphate amidotransferase inhibitor
5-phosphororibosyl-1-pyrophosphate amidotransferase inhibitors
Any EC 2.4.2.* (pentosyltransferase) inhibitor that interferes with the action of amidophosphoribosyltransferase (EC 2.4.2.14).
EC 2.4.2.14 (amidophosphoribosyltransferase) inhibitors
alpha-5-phosphoribosyl-1-pyrophosphate amidotransferase inhibitor
alpha-5-phosphoribosyl-1-pyrophosphate amidotransferase inhibitors
amidophosphoribosyltransferase (EC 2.4.2.14) inhibitor
amidophosphoribosyltransferase (EC 2.4.2.14) inhibitors
amidophosphoribosyltransferase inhibitor
amidophosphoribosyltransferase inhibitors
glutamine 5-phosphoribosylpyrophosphate amidotransferase inhibitor
glutamine 5-phosphoribosylpyrophosphate amidotransferase inhibitors
glutamine phosphoribosyldiphosphate amidotransferase inhibitor
glutamine phosphoribosyldiphosphate amidotransferase inhibitors
glutamine phosphoribosylpyrophosphate amidotransferase inhibitor
glutamine phosphoribosylpyrophosphate amidotransferase inhibitors
glutamine ribosylpyrophosphate 5-phosphate amidotransferase inhibitor
glutamine ribosylpyrophosphate 5-phosphate amidotransferase inhibitors
phosphoribose pyrophosphate amidotransferase inhibitor
phosphoribose pyrophosphate amidotransferase inhibitors
phosphoribosyl pyrophosphate amidotransferase inhibitor
phosphoribosyl pyrophosphate amidotransferase inhibitors
phosphoribosyldiphosphate 5-amidotransferase inhibitor
phosphoribosyldiphosphate 5-amidotransferase inhibitors
phosphoribosylpyrophosphate glutamyl amidotransferase inhibitor
phosphoribosylpyrophosphate glutamyl amidotransferase inhibitors
EC 6.3.5.1 [NAD(+) synthase (glutamine-hydrolysing)] inhibitor
Any EC 6.3.5.* (carbon-nitrogen ligases with glutamine as amido-N-donor) inhibitor that interferes with the action of NAD(+) synthase (glutamine-hydrolysing) (EC 6.3.5.1).
EC 6.3.5.1 [NAD(+) synthase (glutamine-hydrolysing)] inhibitors
NAD synthetase (glutamine-hydrolysing) inhibitor
NAD synthetase (glutamine-hydrolysing) inhibitors
NAD(+) synthase (glutamine-hydrolysing) (EC 6.3.5.1) inhibitor
NAD(+) synthase (glutamine-hydrolysing) (EC 6.3.5.1) inhibitors
NAD(+) synthase (glutamine-hydrolysing) inhibitor
NAD(+) synthase (glutamine-hydrolysing) inhibitors
NAD(+) synthetase (glutamine-hydrolyzing) inhibitor
NAD(+) synthetase (glutamine-hydrolyzing) inhibitors
deamido-NAD(+):L-glutamine amido-ligase (AMP-forming) inhibitor
deamido-NAD(+):L-glutamine amido-ligase (AMP-forming) inhibitors
desamidonicotinamide adenine dinucleotide amidotransferase inhibitor
desamidonicotinamide adenine dinucleotide amidotransferase inhibitors
nicotinamide adenine dinucleotide synthetase (glutamine) inhibitor
nicotinamide adenine dinucleotide synthetase (glutamine) inhibitors
EC 6.3.5.4 [asparagine synthase (glutamine-hydrolysing)] inhibitor
Any EC 6.3.5.* (carbon-nitrogen ligases with glutamine as amido-N-donor) inhibitor that interferes with the action of asparagine synthase (glutamine-hydrolysing), EC 6.3.5.4.
EC 6.3.5.4 [asparagine synthase (glutamine-hydrolysing)] inhibitors
L-aspartate:L-glutamine amido-ligase (AMP-forming) inhibitor
L-aspartate:L-glutamine amido-ligase (AMP-forming) inhibitors
asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) inhibitor
asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) inhibitors
asparagine synthase (glutamine-hydrolysing) inhibitor
asparagine synthase (glutamine-hydrolysing) inhibitors
asparagine synthetase (glutamine-hydrolysing) inhibitor
asparagine synthetase (glutamine-hydrolysing) inhibitors
glutamine-dependent asparagine synthetase inhibitor
glutamine-dependent asparagine synthetase inhibitors
Any compound that interferes with bacterial communication (quorum sensing, QS).
An agonist that binds to and activates thromboxane A2 receptors.
An EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor that inhibits the expression of protein kinase RNA-like endoplasmic reticulum kinase.
PKR-like endoplasmic reticulum kinase inhibitor
PKR-like endoplasmic reticulum kinase inhibitors
protein kinase R-like endoplasmic reticulum kinase inhibitor
protein kinase R-like endoplasmic reticulum kinase inhibitors
An that interferes with the activity of any of the actin-binding kinases that phosphorylate members of the ADF/cofilin family of actin binding and filament severing proteins.
An agonist that activates IP3 receptors.
D-myo-inositol 1,4,5-trisphosphate receptor agonist
D-myo-inositol 1,4,5-trisphosphate receptor agonists
inositol trisphosphate receptor agonists
EC 2.4.1.255 (protein O-GlcNAc transferase) inhibitor
An EC 2.4.1.* (hexosyltransferase) inhibitor that interferes with the action of protein O-GlcNAc transferase (EC 2.4.1.255).
EC 2.4.1.255 (protein O-GlcNAc transferase) inhibitors
O-linked N-acetylglucosaminyltransferase inhibitor
O-linked N-acetylglucosaminyltransferase inhibitors
UDP-N-acetyl-D-glucosamine:protein-O-beta-N-acetyl-D-glucosaminyl transferase inhibitor
UDP-N-acetyl-D-glucosamine:protein-O-beta-N-acetyl-D-glucosaminyl transferase inhibitors
protein O-GlcNAc transferase (EC 2.4.1.255) inhibitor
protein O-GlcNAc transferase (EC 2.4.1.255) inhibitors
protein O-linked beta-N-acetylglucosamine transferase inhibitor
protein O-linked beta-N-acetylglucosamine transferase inhibitors
uridine diphospho-N-acetylglucosamine:polypeptide beta-N-acetylglucosaminyltransferase inhibitor
uridine diphospho-N-acetylglucosamine:polypeptide beta-N-acetylglucosaminyltransferase inhibitors
melanin-concentrating hormone receptor antagonist
An antagonist that attaches to and blocks melanin-concentrating hormone receptors.
melanin-concentrating hormone receptor antagonists
nicotinic acid adenine dinucleotide phosphate receptor antagonist
An antagonist that attaches to and blocks nicotinic acid adenine dinucleotide phosphate receptors.
nicotinic acid adenine dinucleotide phosphate receptor antagonists
A probe that is a small labelled and chemical active peptide which has been structurally modified for reacting with, for example, the beta-lactam moieties of various penicillin-type compounds.
EC 1.14.17.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen and with reduced ascorbate as one donor, and incorporation of one atom of oxygen) inhibitor
EC 1.14.17.1 (dopamine beta-monooxygenase) inhibitor
(3,4-dihydroxyphenethylamine)beta-mono-oxygenase inhibitor
(3,4-dihydroxyphenethylamine)beta-mono-oxygenase inhibitors
3,4-dihydroxyphenethylamine beta-oxidase inhibitor
3,4-dihydroxyphenethylamine beta-oxidase inhibitors
3,4-dihydroxyphenethylamine,ascorbate:oxygen oxidoreductase (beta-hydroxylating) inhibitor
3,4-dihydroxyphenethylamine,ascorbate:oxygen oxidoreductase (beta-hydroxylating) inhibitors
4-(2-aminoethyl)pyrocatechol beta-oxidase inhibitor
4-(2-aminoethyl)pyrocatechol beta-oxidase inhibitors
An EC 1.14.17.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen and with reduced ascorbate as one donor, and incorporation of one atom of oxygen) inhibitor that interferes with the action of dopamine monooxygenase (EC 1.14.17.1).
EC 1.14.17.1 (dopamine beta-monooxygenase) inhibitors
MDBH (membrane-associated dopamine beta-monooxygenase) inhibitor
MDBH (membrane-associated dopamine beta-monooxygenase) inhibitors
SDBH (soluble dopamine beta-monooxygenase) inhibitor
SDBH (soluble dopamine beta-monooxygenase) inhibitors
dopamine beta-monooxygenase (EC 1.14.17.1) inhibitor
dopamine beta-monooxygenase (EC 1.14.17.1) inhibitors
oxygenase, dopamine beta-mono-phenylamine beta-hydroxylase inhibitor
oxygenase, dopamine beta-mono-phenylamine beta-hydroxylase inhibitors
An agent that inhibits the passage of cations through the transient receptor potential (TRP) channels.
transient receptor potential channel blocker
transient receptor potential channel blockers
A chemical compound that causes a substantial proportion of exposed people or animals to develop an allergic reaction in normal tissue after repeated exposure to the compound.
An agonist that binds to and activates vitamin D receptors
EC 1.3.1.9 [enoyl-[acyl-carrier-protein] reductase (NADH)] inhibitor
An EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of enoyl-[acyl-carrier-protein] reductase (NADH), EC 1.3.1.9.
EC 1.3.1.9 [enoyl-[acyl-carrier-protein] reductase (NADH)] inhibitors
NADH-enoyl acyl carrier protein reductase inhibitor
NADH-enoyl acyl carrier protein reductase inhibitors
NADH-specific enoyl-ACP reductase inhibitor
NADH-specific enoyl-ACP reductase inhibitors
acyl-[acyl-carrier-protein]:NAD+ oxidoreductase inhibitor
acyl-[acyl-carrier-protein]:NAD+ oxidoreductase inhibitors
enoyl-[acyl carrier protein] reductase inhibitor
enoyl-[acyl carrier protein] reductase inhibitors
EC 4.1.1.17 (ornithine decarboxylase) inhibitor
An EC 4.1.1.* (carboxy-lyase) inhibitor that interferes with the action of ornithine decarboxylase (EC 4.1.1.17).
EC 4.1.1.17 (ornithine decarboxylase) inhibitors
L-ornithine carboxy-lyase (putrescine-forming) inhibitor
L-ornithine carboxy-lyase (putrescine-forming) inhibitors
Any plant metabolite that is produced by the genus Jacobaea.
lysophosphatidic acid receptor 3 agonist
An agonist that binds to and activates lysophosphatidic acid 3 receptors.
lysophosphatidic acid receptor 3 agonists
An apoptosis inducer that works by selectively inhibiting survivin (BIRC5) gene promoter activity so as to down-regulate survivin, a protein that inhibits apoptosis, so leading to induction of apoptosis.
An agonist at the transient receptor potential vanilloid 4 (TRPV4).
OSM9-like transient receptor potential channel, member 4 agonist
OSM9-like transient receptor potential channel, member 4 agonists
transient receptor potential cation channel subfamily V member 4 agonist
transient receptor potential cation channel subfamily V member 4 agonists
transient receptor potential vanilloid 4 agonists
vanilloid-receptor related osmotically activated channel agonist
vanilloid-receptor related osmotically activated channel agonists
Any plant metabolite that is produced by Camellia sinensis.
Any plant metabolite that is produced by rapeseed (Brassica napus).
Any antimicrobial agent whose activity is dependent on the presence of calcium ions.
EC 1.1.1.37 (malate dehydrogenase) inhibitor
(S)-malate:NAD(+) oxidoreductase inhibitor
(S)-malate:NAD(+) oxidoreductase inhibitors
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of any malate dehydrogenase (EC 1.1.1.37).
EC 1.1.1.37 (malate dehydrogenase) inhibitors
L-malate-NAD(+) oxidoreductase inhibitor
L-malate-NAD(+) oxidoreductase inhibitors
NAD-dependent malate dehydrogenase inhibitor
NAD-dependent malate dehydrogenase inhibitors
NAD-dependent malic dehydrogenase inhibitor
NAD-dependent malic dehydrogenase inhibitors
NAD-linked malate dehydrogenase inhibitor
NAD-linked malate dehydrogenase inhibitors
NAD-specific malate dehydrogenase inhibitor
NAD-specific malate dehydrogenase inhibitors
malate dehydrogenase (EC 1.1.1.37) inhibitor
malate dehydrogenase (EC 1.1.1.37) inhibitors
A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation.
An antagonist at the neurokinin-3 receptor.
tropomyosin-related kinase B receptor agonist
An agonist that binds to and deactivates the tropomyosin-related kinase B (TrkB) receptor, the main signaling receptor of the neurotrophin brain-derived neurotrophic factor (BDNF).
tropomyosin-related kinase B receptor agonists
An agonist at the transient receptor potential vanilloid 1 (TRPV1).
transient receptor potential vanilloid 1 agonist
transient receptor potential vanilloid 1 agonists
Any plant metabolite that is produced by Arabidopsis thaliana.
secreted frizzled-related protein 1 inhibitor
Any inhibitor of secreted frizzled-related protein 1 (SFRP1). The level of SFRP1 affects osteoblast apoptosis and proliferation, so SFRP1 inhibitors have the potential to be used for the treatment of osteoporosis or other bone related disorders.
secreted frizzled-related protein 1 inhibitors
secreted frizzled-related protein-1 inhibitor
secreted frizzled-related protein-1 inhibitors
Any pathway inhibitor that inhibits the Hedgehog signalling pathway.
An inhibitor of any of the glioma-associated oncogene (GLI) proteins.
An antagonist that binds to and deactivates neuropeptide FF receptors.
An agonist that activates neuropeptide FF (NPFF) receptors.
An agonist that acts at the kisspeptin receptor (KISS1R).
A mitochondrial cytochrome-bc1 complex inhibitor that acts at the Quinone 'outer' (Qo) binding site of the cytochrome-bc1 complex.
A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active nematicide for which it is a pronematicide.
5-hydroxytryptamine 2B receptor agonists
5-hydroxytryptamine receptor 2B agonists
An agonist at the 5-hydroxytryptamine 2B (5-HT2B) receptor.
5-hydroxytryptamine 2C receptor agonists
5-hydroxytryptamine receptor 2C agonists
An agonist at the 5-hydroxytryptamine 2B (5-HT2C) receptor.
EC 1.14.14.94 (leukotriene-B4 20-monooxygenase) inhibitor
(6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (20-hydroxylating) inhibitor
(6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (20-hydroxylating) inhibitors
Any EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor that interferes with the action of leukotriene-B4 20-monooxygenase (EC 1.14.14.94).
EC 1.14.14.94 (leukotriene-B4 20-monooxygenase) inhibitors
leucotriene-B4 omega-hydroxylase inhibitor
leucotriene-B4 omega-hydroxylase inhibitors
leukotriene-B4 20-hydroxylase inhibitors
leukotriene-B4 20-monooxygenase (EC 1.14.14.94) inhibitors
leukotriene-B4 20-monooxygenase inhibitor
leukotriene-B4 20-monooxygenase inhibitors
EC 1.14.15.3 (alkane 1-monooxygenase) inhibitor
Any EC 1.14.15.* (oxidoreductase acting on paired donors, with reduced Fe-S protein as one donor, incorporating 1 O atom) inhibitor that interferes with the action of alkane 1-monooxygenase (EC 1.14.15.3).
EC 1.14.15.3 (alkane 1-monooxygenase) inhibitors
alkane 1-monooxygenase (EC 1.14.15.3) inhibitor
alkane 1-monooxygenase (EC 1.14.15.3) inhibitors
alkane,reduced-rubredoxin:oxygen 1-oxidoreductase inhibitor
alkane,reduced-rubredoxin:oxygen 1-oxidoreductase inhibitors
EC 4.1.1.15 (glutamate decarboxylase) inhibitor
An EC 4.1.1.* (carboxy-lyase) inhibitor that interferes with the action of glutamate decarboxylase (EC 4.1.1.15).
EC 4.1.1.15 (glutamate decarboxylase) inhibitors
L-aspartate-alpha-decarboxylase inhibitor
L-aspartate-alpha-decarboxylase inhibitors
L-glutamate 1-carboxy-lyase (4-aminobutanoate-forming) inhibitor
L-glutamate 1-carboxy-lyase (4-aminobutanoate-forming) inhibitors
L-glutamate alpha-decarboxylase inhibitor
L-glutamate alpha-decarboxylase inhibitors
L-glutamic acid decarboxylase inhibitors
gamma-glutamate decarboxylase inhibitors
glutamate decarboxylase (EC 4.1.1.15) inhibitor
glutamate decarboxylase (EC 4.1.1.15) inhibitors
A chemical that inhibits the aggregation of the tau protein (HGNC:MAPT) and its distinct morphological forms (e.g. paired helical fragments (PHFs), straight filaments (SFs), oligomers, or larger aggregates).
EC 2.5.1.117 (homogentisate solanesyltransferase) inhibitor
Any transient receptor potential (TRP) channel modulator that modulates the TRPV channels (V = vanilloid). There is strong evidence that action at one or more of this class of proteins is responsible for the insecticidal action of pymetrozine, pyrifluquinazon, and afidopyropen.
transient receptor potential (vanilloid) channel modulator
transient receptor potential (vanilloid) channel modulators
An agent that modulates the passage of cations through the transient receptor potential (TRP) channels.
EC 3.3.2.10 (soluble epoxide hydrolase) inhibitor
Any inhibitor of soluble epoxide hydrolase, a bifunctional enzyme that in humans is encoded by the EPHX2 gene.Found in both the cytosol and peroxisomes it binds to specific epoxides and converts them into the corresponding diols.
EC 2.1.3.* (carboxy- and carbamoyltransferases) inhibitor
An EC 2.1.* (C1-transferase) inhibitor that interferes with the action of any carboxy- and carbamoyltransferases (EC 2.1.3.*).
EC 2.1.3.* (carboxy- and carbamoyltransferases) inhibitors
EC 2.1.3.* (carboxytransferase and carbamoyltransferase) inhibitor
EC 2.1.3.* (carboxytransferase and carbamoyltransferase) inhibitors
carboxy- and carbamoyltransferase (EC 2.1.3.*) inhibitor
carboxy- and carbamoyltransferase (EC 2.1.3.*) inhibitors
EC 2.1.3.3 (ornithine carbamoyltransferase) inhibitor
Any EC 2.1.3.* (carboxy- and carbamoyltransferases) inhibitor that inhibits the action of ornithine carbamoyltransferase (EC 2.1.3.3).
EC 2.1.3.3 (ornithine carbamoyltransferase) inhibitors
L-ornithine carbamoyltransferase inhibitor
L-ornithine carbamoyltransferase inhibitors
L-ornithine carbamyltransferase inhibitor
L-ornithine carbamyltransferase inhibitors
carbamoyl-phosphate:L-ornithine carbamoyltransferase inhibitor
carbamoyl-phosphate:L-ornithine carbamoyltransferase inhibitors
carbamylphosphate-ornithine transcarbamylase inhibitor
carbamylphosphate-ornithine transcarbamylase inhibitors
ornithine carbamoyltransferase (EC 2.1.3.3) inhibitor
ornithine carbamoyltransferase (EC 2.1.3.3) inhibitors
ornithine carbamoyltransferase inhibitor
ornithine carbamoyltransferase inhibitors
ornithine carbamyltransferase inhibitors
A chemical role played by any unwanted chemical substance inside a confined amount of liquid, gas, or solid, which differs from the chemical composition of the material or compound. For example, an impurity can be an undesired by-product of a chemical reaction or manufacturing process, a drug contaminant, or can be created upon degradation during storage.
Any peptide which causes the onset of an allergic reaction.
Any carbohydrate, carbohydrate derivative or derived substituent group which causes the onset of an allergic reaction.
Any ceramide which causes the onset of an allergic reaction.
EC 1.14.14.154 (sterol 14alpha-demethylase) inhibitor
Any EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor that interferes with the action of sterol 14alpha-demethylase (EC 1.14.14.154).
EC 1.14.14.154 (sterol 14alpha-demethylase) inhibitors
lanosterol 14alpha-demethylase inhibitor
lanosterol 14alpha-demethylase inhibitors
oxidoreductase (14-methyl cleaving) inhibitors
sterol 14alpha-demethylase (EC 1.14.14.154) inhibitor
sterol 14alpha-demethylase (EC 1.14.14.154) inhibitors
sterol,[reduced NADPH--hemoprotein reductase]:oxygen inhibitor
sterol,[reduced NADPH--hemoprotein reductase]:oxygen oxidoreductase (14-methyl cleaving) inhibitor
An EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor that interferes with the action of pyruvate kinase (EC 2.7.1.40).
phosphoenol transphosphorylase inhibitor
phosphoenol transphosphorylase inhibitors
EC 1.14.15.6 cholesterol monooxygenase (side-chain-cleaving) inhibitor
Any EC 1.14.15.* (oxidoreductase acting on paired donors, with reduced Fe-S protein as one donor, incorporating 1 O atom) inhibitor that interferes with the action of cholesterol monooxygenase (side-chain-cleaving) (EC 1.14.15.6).
C27-side chain cleavage enzyme inhibitor
C27-side chain cleavage enzyme inhibitors
cholesterol monooxygenase (side-chain-cleaving) inhibitor
cholesterol monooxygenase (side-chain-cleaving) inhibitors
cholesterol side-chain cleavage enzyme inhibitor
cholesterol side-chain cleavage enzyme inhibitors
cholesterol side-chain-cleaving enzyme inhibitor
cholesterol side-chain-cleaving enzyme inhibitors
EC 1.4.3.2 (L-amino-acid oxidase) inhibitor
Any EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor that interferes with the action of L-amino-acid oxidase (EC 1.4.3.2).
EC 1.4.3.2 (L-amino-acid oxidase) inhibitors
L-amino-acid oxidase inhibitor (EC 1.4.3.2) inhibitor
L-amino-acid oxidase inhibitor (EC 1.4.3.2) inhibitors
L-amino-acid:oxygen oxidoreductase (deaminating) inhibitor
L-amino-acid:oxygen oxidoreductase (deaminating) inhibitors
EC 2.6.1.2 (alanine transaminase) inhibitor
EC 2.7.1.105 (6-phosphofructo-2-kinase) inhibitor
6-phosphofructo-2-kinase (phosphorylating) inhibitor
6-phosphofructo-2-kinase (phosphorylating) inhibitors
An EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor that interferes with the action of 6-phosphofructo-2-kinase (EC 2.7.1.105).
fructose 6-phosphate 2-kinase inhibitors
EC 3.1.1.64 (retinoid isomerohydrolase) inhibitor
An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of retinoid isomerohydrolase (EC 3.1.1.64).
EC 3.1.1.64 (retinoid isomerohydrolase) inhibitors
all-trans-retinol isomerase:hydrolase inhibitor
all-trans-retinol isomerase:hydrolase inhibitors
all-trans-retinyl-palmitate hydrolase inhibitor
all-trans-retinyl-palmitate hydrolase inhibitors
all-trans-retinylester 11-cis isomerohydrolase inhibitor
all-trans-retinylester 11-cis isomerohydrolase inhibitors
An antigenic substance produced in tumour cells, which triggers an immune response in the host.
cluster of differentiation 88 antagonist
cluster of differentiation 88 antagonists
complement component 5a receptor 1 antagonist
complement component 5a receptor 1 antagonists
EC 3.6.5.2 (small monomeric GTPase) inhibitor
sphingosine-1-phosphate receptor antagonist
An antagonist that binds to and blocks sphingosine 1-phosphate receptors, a class of G protein-coupled receptors that are targets of the lipid signalling molecule sphingosine-1-phosphate (S1P).
sphingosine 1-phosphate receptor antagonist
sphingosine 1-phosphate receptor antagonists
sphingosine-1-phosphate receptor antagonists
sphingosine-1-phosphate receptor 3 antagonist
Any sphingosine-1-phosphate receptor (S1PR) antagonist that acts as an antagonist towards the subtype 3 receptors (S1PR3).
sphingosine-1-phosphate receptor 3 antagonists
sphingosine-1-phosphate receptor 1 antagonist
Any sphingosine-1-phosphate receptor (S1PR) antagonist that acts as an antagonist for the subtype 1 receptors (S1PR1).
sphingosine-1-phosphate receptor 1 antagonists
An agent that destroy spermatozoa in the male genitalia and block spermatogenesis.
Any inhibitor that interferes with the synthesis of hyaluronic acid (HA, also known as hyaluronan).
EC 1.1.1.42 (isocitrate dehydrogenase) inhibitor
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of any isocitrate dehydrogenase (EC 1.1.1.42).
NADP(+)-linked isocitrate dehydrogenase inhibitor
NADP(+)-linked isocitrate dehydrogenase inhibitors
NADP-dependent isocitrate dehydrogenase inhibitor
NADP-dependent isocitrate dehydrogenase inhibitors
NADP-dependent isocitric dehydrogenase inhibitor
NADP-dependent isocitric dehydrogenase inhibitors
NADP-linked isocitrate dehydrogenase inhibitor
NADP-linked isocitrate dehydrogenase inhibitors
NADP-specific isocitrate dehydrogenase inhibitor
NADP-specific isocitrate dehydrogenase inhibitors
dual-cofactor-specific isocitrate dehydrogenase inhibitor
dual-cofactor-specific isocitrate dehydrogenase inhibitors
isocitrate (NADP) dehydrogenase inhibitor
isocitrate (NADP) dehydrogenase inhibitors
isocitrate (nicotinamide adenine dinucleotide phosphate) dehydrogenase inhibitor
isocitrate (nicotinamide adenine dinucleotide phosphate) dehydrogenase inhibitors
isocitrate dehydrogenase (NADP(+)) inhibitor
isocitrate dehydrogenase (NADP(+)) inhibitors
isocitrate dehydrogenase (NADP-dependent) inhibitor
isocitrate dehydrogenase (NADP-dependent) inhibitors
triphosphopyridine nucleotide-linked isocitrate dehydrogenase-oxalosuccinate carboxylase inhibitor
triphosphopyridine nucleotide-linked isocitrate dehydrogenase-oxalosuccinate carboxylase inhibitors
An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of any polo kinase (EC 2.7.11.21).
serine/threonine-specific Drosophila kinase polo inhibitor
serine/threonine-specific Drosophila kinase polo inhibitors
Any inhibitor that acts on uncoupling protein.
mitochondrial uncoupling protein inhibitor
mitochondrial uncoupling protein inhibitors
C-X-C chemokine receptor type 4 antagonist
An antogonist that blocks C-X-C chemokine receptor type 4 (CXCR-4).
C-X-C chemokine receptor type 4 antagonists
C-X-C motif chemokine receptor 4 antagonist
C-X-C motif chemokine receptor 4 antagonists
chemokine (C-X-C motif) receptor 4 antagonist
chemokine (C-X-C motif) receptor 4 antagonists
Any inhibitor that acts on forkhead box protein O1 (FOXO1).
EC 1.2.1.11 (aspartate-semialdehyde dehydrogenase) inhibitor
Any EC 1.2.1.* (oxidoreductase acting on donor aldehyde/oxo group with NAD(+) or NADP(+) as acceptor) inhibitor that inhibits the action of aspartate-semialdehyde dehydrogenase (EC 1.2.1.11).
EC 1.2.1.11 (aspartate-semialdehyde dehydrogenase) inhibitors
L-aspartate-4-semialdehyde:NADP+ oxidoreductase (phosphorylating) inhibitor
L-aspartate-4-semialdehyde:NADP+ oxidoreductase (phosphorylating) inhibitors
L-aspartate-beta-semialdehyde:NADP oxidoreductase (phosporylating) inhibitor
L-aspartate-beta-semialdehyde:NADP oxidoreductase (phosporylating) inhibitors
aspartate semialdehyde dehydrogenase inhibitor
aspartate semialdehyde dehydrogenase inhibitors
aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) inhibitor
aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) inhibitors
aspartate-semialdehyde dehydrogenase inhibitor
aspartate-semialdehyde dehydrogenase inhibitors
aspartic beta-semialdehyde dehydrogenase inhibitor
aspartic beta-semialdehyde dehydrogenase inhibitors
aspartic semialdehyde dehydrogenase inhibitor
aspartic semialdehyde dehydrogenase inhibitors
A cardiovascular drug that prevents atherosclerosis (a disease in which the inside of an artery narrows due to the build up of plaque). Compare with antiatherogenic agent.
5-hydroxytryptamine 2A receptor agonists
5-hydroxytryptamine receptor 2A agonists
An agonist at the 5-hydroxytryptamine 2A (5-HT2A) receptor.
A cannabinoid receptor agonist that binds to and activates type 2 cannabinoid receptors.
Any substance that produces or enhances dream-like states of consciousness.
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor
An EC 3.4.22.* (cysteine endopeptidase) inhibitor that interferes with the action of SARS coronavirus main proteinase (EC 3.4.22.69).
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitors
SARS coronavirus 3CL protease inhibitors
SARS coronavirus main peptidase inhibitor
SARS coronavirus main peptidase inhibitors
SARS coronavirus main protease inhibitor
SARS coronavirus main protease inhibitors
SARS coronavirus main proteinase inhibitor
SARS coronavirus main proteinase inhibitors
severe acute respiratory syndrome coronavirus main protease inhibitor
severe acute respiratory syndrome coronavirus main protease inhibitors
EC 3.4.17.23 (angiotensin-converting enzyme 2) inhibitor
Any EC 3.4.17.* (metallocarboxypeptidase) inhibitor that inhibits the action of angiotensin-converting enzyme 2 (EC 3.4.17.23).
EC 3.4.17.23 (angiotensin-converting enzyme 2) inhibitors
angiotensin converting enzyme 2 inhibitor
angiotensin converting enzyme 2 inhibitors
angiotensin converting enzyme-2 inhibitor
angiotensin converting enzyme-2 inhibitors
angiotensin-converting enzyme 2 inhibitor
angiotensin-converting enzyme 2 inhibitors
EC 3.4.17* (metallocarboxypeptidase) inhibitor
Any EC 3.4.* (hydrolases acting on peptide bond) inhibitor that inhibits the action of a metallocarboxypeptidase (EC 3.4.17.*).
EC 3.4.17* (metallocarboxypeptidase) inhibitors
Any inhibitor added to nitrogen fertilizers which can reduce the rate at which ammonium is converted to nitrate. Under appropriate conditions, this can help reduce nitrogen losses through denitrification and leaching.
A reagent used in electron paramagnetic resonance (EPR) spectroscopy to react covalently with radical products whose half-life is be too short to detect. The resulting adducts are more stable enabling their paramagnetic resonance spectra to be obtained.
Any agent that induces nausea and vomiting.
Any antiviral agent which inhibits the activity of coronaviruses.
EC 2.3.3.8 (ATP citrate synthase) inhibitor
ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO(-)->acetyl-CoA] (ATP-dephosphorylating) inhibitor
ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO(-)->acetyl-CoA] (ATP-dephosphorylating) inhibitors
An EC 2.3.3.* (acyltransferase converting acyl to alkyl group on transfer) inhibitor that interferes with the action of ATP citrate synthase (EC 2.3.3.8).
EC 2.3.3.8 (ATP citrate synthase) inhibitors
acetyl-CoA:oxaloacetate acetyltransferase (isomerizing, ADP-phosphorylating) inhibitor
acetyl-CoA:oxaloacetate acetyltransferase (isomerizing, ADP-phosphorylating) inhibitors
adenosine triphosphate citrate lyase inhibitor
adenosine triphosphate citrate lyase inhibitors
EC 3.4.21.36 (pancreatic elastase) inhibitor
An EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the activity of pancreatic elastase (EC 3.4.21.36).
EC 3.4.21.36 (pancreatic elastase) inhibitors
pancreatic elastase (EC 3.4.21.36) inhibitor
pancreatic elastase (EC 3.4.21.36) inhibitors
An antogonist that blocks chemokine receptor 2 (CCR2).
C-C chemokine receptor type 2 antagonist
C-C chemokine receptor type 2 antagonists
Any compound that activates Sarcoplasmic/Endoplasmic Reticulum Calcium-ATPase (EC 7.2.2.10).
Sarcoplasmic/Endoplasmic Reticulum Calcium-ATPase activator
Sarcoplasmic/Endoplasmic Reticulum Calcium-ATPase activators
A molecular entity that can transfer an electron to another molecular entity.
A molecular entity that can accept an electron, a pair of electrons, an atom or a group from another molecular entity.
A topoisomerase inhibitor that inhibits DNA topoisomerase II.
An agonist that selectively binds to and activates mucosal associated invariant T cells (MAIT cells).
mucosal associated invariant T cell agonist
mucosal associated invariant T cell agonists
An EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of furin (EC 3.4.21.75).
paired basic amino acid cleaving enzyme inhibitor
paired basic amino acid cleaving enzyme inhibitors
paired basic amino acid converting enzyme inhibitor
paired basic amino acid converting enzyme inhibitors
EC 2.4.1.109 (dolichyl-phosphate-mannose-protein mannosyltransferase) inhibitor
An EC 2.4.1.* (hexosyltransferase) inhibitor that interferes with the action of dolichyl-phosphate-mannose-protein mannosyltransferase (EC 2.4.1.109).
EC 2.4.1.109 (dolichyl-phosphate-mannose-protein mannosyltransferase) inhibitors
dolichol phosphomannose-protein mannosyltransferase inhibitor
dolichol phosphomannose-protein mannosyltransferase inhibitors
dolichyl-D-mannosyl-phosphate:protein O-D-mannosyltransferase inhibitor
dolichyl-D-mannosyl-phosphate:protein O-D-mannosyltransferase inhibitors
dolichyl-phosphate-D-mannose:protein O-D-mannosyltransferase inhibitor
dolichyl-phosphate-D-mannose:protein O-D-mannosyltransferase inhibitors
dolichyl-phosphate-mannose--protein mannosyltransferase inhibitor
dolichyl-phosphate-mannose--protein mannosyltransferase inhibitors
protein O-D-mannosyltransferase inhibitor
protein O-D-mannosyltransferase inhibitors
Any member of the class of organooxygen compounds that is a polyhydroxy-aldehyde or -ketone or a lactol resulting from their intramolecular condensation (monosaccharides); substances derived from these by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom; and polymeric products arising by intermolecular acetal formation between two or more such molecules (disaccharides, polysaccharides and oligosaccharides). Carbohydrates contain only carbon, hydrogen and oxygen atoms; prior to any oxidation or reduction, most have the empirical formula Cm(H2O)n. Compounds obtained from carbohydrates by substitution, etc., are known as carbohydrate derivatives and may contain other elements. Cyclitols are generally not regarded as carbohydrates.
An EC 3.4.23.* (aspartic endopeptidase) inhibitor that interferes with the activity of renin (EC 3.4.23.15).
A chelator that is any compound containing a ligand (typically organic) which is able to form a bond to a central copper atom at two or more points.
An antagonist that binds to and deactivates neuropilin receptors.
Any compound that exhibits antagonist activity at the kappa-opioid receptor.
A substance which is poisonous to fish and is primarily used to eliminate dominant species of fish in water.
Any insecticide that is capable of killing egg cells.
Any inhibitor which inhibits the activity of cleavage and polyadenylation specificity factor subunit 3 protein (CPSF3).
cleavage and polyadenylation specific factor 3 inhibitor
cleavage and polyadenylation specific factor 3 inhibitors
cleavage and polyadenylation specificity factor 73 KDa subunit inhibitor
cleavage and polyadenylation specificity factor 73 KDa subunit inhibitors
cleavage and polyadenylation specificity factor subunit 3 inhibitor
cleavage and polyadenylation specificity factor subunit 3 inhibitors
EC 6.1.1.6 (lysine--tRNA ligase) inhibitor
An EC 6.1.1.* (ligases forming aminoacyl tRNA and related compounds) inhibitor that specifically inhibits the action of lysine-tRNA ligase (EC 6.1.1.6).
EC 6.1.1.6 (lysine--tRNA ligase) inhibitors
L-lysine:tRNA(Lys) ligase (AMP-forming) inhibitor
L-lysine:tRNA(Lys) ligase (AMP-forming) inhibitors
lysyl-transfer RNA synthetase inhibitors
lysyl-transfer ribonucleate synthetase inhibitor
lysyl-transfer ribonucleate synthetase inhibitors
EC 2.1.1.43 (enhancer of zeste homolog 2) inhibitor
An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of Enhancer of zeste homolog 2 (EZH2), a histone-lysine N-methyltransferase (EC 2.1.1.43).
EC 2.1.1.43 (enhancer of zeste homolog 2) inhibitors
Any substance that inhibits the process of necroptosis (programmed form of necrosis) in organisms.
EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor
A DNA polymerase inhibitor that interferes with the action of a RNA-directed RNA polymerase (EC 2.7.7.48).
EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitors
RNA nucleotidyltransferase (RNA-directed) inhibitor
RNA nucleotidyltransferase (RNA-directed) inhibitors
RNA-dependent ribonucleate nucleotidyltransferase inhibitor
RNA-dependent ribonucleate nucleotidyltransferase inhibitors
ribonucleic acid-dependent ribonucleate nucleotidyltransferase inhibitor
ribonucleic acid-dependent ribonucleate nucleotidyltransferase inhibitors
ribonucleic acid-dependent ribonucleic acid polymeras inhibitor
ribonucleic acid-dependent ribonucleic acid polymeras inhibitors
An antiparasitic agent which is effective against amoeba, a genus of single-celled amoeboids in the family Amoebidae.
EC 2.1.1.348 (mRNA m6A methyltransferase) inhibitor
An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of mRNA m6A methyltransferase (EC 2.1.1.348).
EC 2.1.1.348 (mRNA m6A methyltransferase) inhibitors
EC 2.6.1.11 (acetylornithine transaminase) inhibitor
2-N-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase inhibitor
2-N-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase inhibitors
An EC 2.6.1.* (transaminase) inhibitor that interferes with the action of acetylornithine transaminase (EC 2.6.1.11).
EC 2.6.1.11 (acetylornithine transaminase) inhibitors
N(2)-acetyl-L-ornithine:2-oxoglutarate aminotransferase inhibitor
N(2)-acetyl-L-ornithine:2-oxoglutarate aminotransferase inhibitors
N(2)-acetylornithine 5-transaminase inhibitor
N(2)-acetylornithine 5-transaminase inhibitors
N-acetylornithine aminotransferase inhibitor
N-acetylornithine aminotransferase inhibitors
N-acetylornithine-delta-transaminase inhibitor
N-acetylornithine-delta-transaminase inhibitors
acetylornithine 5-aminotransferase inhibitor
acetylornithine 5-aminotransferase inhibitors
acetylornithine aminotransferase inhibitor
acetylornithine aminotransferase inhibitors
acetylornithine delta-transaminase inhibitor
acetylornithine delta-transaminase inhibitors
succinylornithine aminotransferase inhibitor
succinylornithine aminotransferase inhibitors
An antimicrobial agent that is added to cosmetic formulations to maintain the microbiological safety of the products by inhibiting the growth of fungi or bacteria.
Any substance that inhibits the process of ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms.
Any substance that induces or promotes ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms.
EC 3.1.3.25 (inositol-phosphate phosphatase) inhibitor
An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of inositol-phosphate phosphatase (EC 3.1.3.25).
EC 3.1.3.25 (inositol-phosphate phosphatase) inhibitors
L-myo-inositol-1-phosphate phosphatase inhibitor
L-myo-inositol-1-phosphate phosphatase inhibitors
inositol monophosphate phosphatase inhibitor
inositol monophosphate phosphatase inhibitors
inositol phosphate phosphatase inhibitor
inositol phosphate phosphatase inhibitors
inositol-1(or 4)-monophosphatase inhibitor
inositol-1(or 4)-monophosphatase inhibitors
inositol-phosphate phosphatase inhibitor
inositol-phosphate phosphatase inhibitors
myo-inositol-1(or 4)-monophosphatase inhibitor
myo-inositol-1(or 4)-monophosphatase inhibitors
myo-inositol-1(or 4)-phosphate phosphohydrolase inhibitor
myo-inositol-1(or 4)-phosphate phosphohydrolase inhibitors
voltage-dependent anion channel inhibitor
Any agent that inhibits voltage-dependent anion channels.
voltage-dependent anion channel blockers
voltage-dependent anion channel inhibitors
voltage-dependent anion-selective channel blocker
voltage-dependent anion-selective channel blockers
voltage-dependent anion-selective channel inhibitor
voltage-dependent anion-selective channel inhibitors
Any substance which inhibits thioredoxin, a group of small redox proteins.
An androstanoid having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5..
EC 1.11.1.9 (glutathione peroxidase) inhibitor
An inhibitor of peroxidases (EC 1.11.1.*) that inhibits the action of glutathione peroxidase (EC 1.11.1.9).
EC 1.11.1.9 (glutathione peroxidase) inhibitors
reduced glutathione peroxidase inhibitor
reduced glutathione peroxidase inhibitors
selenium-glutathione peroxidase inhibitor
selenium-glutathione peroxidase inhibitors
Any substance that induces the polymerisation of the protein actin.
Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.
ferroptosis suppressor protein 1 inhibitor
An inhibitor which inhibits the action of ferroptosis suppressor protein 1.
apoptosis-inducing factor mitochondria-associated 2 inhibitor
apoptosis-inducing factor mitochondria-associated 2 inhibitors
ferroptosis suppressor protein 1 inhibitors
A substance to which an electron may be transferred.
EC 2.7.11.2 - [pyruvate dehydrogenase (acetyl-transferring)] kinase inhibitor
An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of pyruvate dehydrogenase (acetyl-transferring) kinase (EC 2.7.11.2).
EC 2.7.11.2 - [pyruvate dehydrogenase (acetyl-transferring)] kinase inhibitors
[pyruvate dehydrogenase (acetyl-transferring)] kinase inhibitor
[pyruvate dehydrogenase (acetyl-transferring)] kinase inhibitors
pyruvate dehydrogenase (acetyl-transferring) kinase inhibitor
pyruvate dehydrogenase (acetyl-transferring) kinase inhibitors
pyruvate dehydrogenase kinase (phosphorylating) inhibitor
pyruvate dehydrogenase kinase (phosphorylating) inhibitors
pyruvate dehydrogenase kinase activator protein inhibitor
pyruvate dehydrogenase kinase activator protein inhibitors
pyruvate dehydrogenase kinase inhibitors
An agonist that binds to and activates somatostatin receptors.
A molecular entity that can transfer ("donate") an electron, a pair of electrons, an atom or a group to another molecular entity.
A mainly tumour-specific antigen generated by mutations in tumour cells. Neoantigens are only expressed in tumour cells.
EC 3.2.1.52 (beta-N-acetylhexosaminidase) inhibitor
An EC 3.2.1.* (glycosidase) inhibitor that interferes with the action of beta-N-acetylhexosaminidase (EC 3.2.1.52).
EC 3.2.1.52 (beta-N-acetylhexosaminidase) inhibitors
N-acetyl-beta-D-hexosaminidase inhibitor
N-acetyl-beta-D-hexosaminidase inhibitors
beta-D-N-acetylhexosaminidase inhibitors
beta-N-acetyl-D-hexosaminidase inhibitor
beta-N-acetyl-D-hexosaminidase inhibitors
beta-acetylaminodeoxyhexosidase inhibitor
beta-acetylaminodeoxyhexosidase inhibitors
EC 1.14.14.91 ( trans-cinnamate 4-monooxygenase) inhibitor
Any EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor that interferes with the action of trans-cinnamate 4-monooxygenase (EC 1.14.14.91).
EC 1.14.14.91 ( trans-cinnamate 4-monooxygenase) inhibitors
cinnamic acid 4-monooxygenase inhibitors
cytochrome P450 cinnamate 4-hydroxylase inhibitor
cytochrome P450 cinnamate 4-hydroxylase inhibitors
trans-cinnamate 4-hydroxylase inhibitors
trans-cinnamate 4-monooxygenase inhibitor
trans-cinnamate 4-monooxygenase inhibitors
trans-cinnamic acid 4-hydroxylase inhibitor
trans-cinnamic acid 4-hydroxylase inhibitors
Any herbicide composed of urea or substituted urea substructure.
An EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of kexin (EC 3.4.21.61).
Kex2-like precursor protein processing endoprotease inhibitor
Kex2-like precursor protein processing endoprotease inhibitors
andrenorphin-Gly-generating enzyme inhibitor
andrenorphin-Gly-generating enzyme inhibitors
prohormone-processing KEX2 proteinase inhibitor
prohormone-processing KEX2 proteinase inhibitors
prohormone-processing endoprotease inhibitor
prohormone-processing endoprotease inhibitors
prohormone-processing proteinase inhibitor
prohormone-processing proteinase inhibitors
a group of substances that bind to a receptor to change that receptor's response to stimulus.
protease-activated receptor-2 antagonist
An antagonist at the protease-activated receptor-2.
G-protein coupled receptor 11 antagonist
G-protein coupled receptor 11 antagonists
coagulation factor II (thrombin) receptor-like 1 antagonist
coagulation factor II (thrombin) receptor-like 1 antagonists
protease-activated receptor 2 antagonist
protease-activated receptor 2 antagonists
protease-activated receptor-2 antagonists
Any receptor modulator acting on sigma receptors.
A sigma receptor modulator that activates the sigma-2 receptor.
Any compound that mimics the activity of a ceramide, e.g. by inducing tumor cell death or suppression.
EC 3.2.1.24 (alpha-mannosidase) inhibitor
An EC 3.2.1.* (glycosidase) inhibitor that interferes with the action of alpha-mannosidase (EC 3.2.1.24).
EC 3.2.1.24 (alpha-mannosidase) inhibitors
p-nitrophenyl-alpha-mannosidase inhibitor
p-nitrophenyl-alpha-mannosidase inhibitors
A cannabinoid receptor agonist that binds to and activates type 1 cannabinoid receptors.
A chemical or biochemical compound that is introduced in small concentrations to a living system to promote the biosynthesis of the target bioactive compound.
EC 6.2.1.45 (E1 ubiquitin-activating enzyme) inhibitor
An EC 6.2.1.* (acid-thiol ligase) inhibitor that interferes with the action of E1 ubiquitin-activating enzyme (EC 6.2.1.45).
E1 ubiquitin-activating enzyme inhibitor
E1 ubiquitin-activating enzyme inhibitors
EC 6.2.1.45 (E1 ubiquitin-activating enzyme) inhibitors
ubiquitin-activating enzyme E1 inhibitor
ubiquitin-activating enzyme E1 inhibitors
An agonist at the neurokinin-1 receptor.
An agonist at the protease-activated receptor-1.
coagulation factor II (thrombin) receptor agonist
coagulation factor II (thrombin) receptor agonists
coagulation factor II thrombin receptor agonist
coagulation factor II thrombin receptor agonists
proteinase-activated receptor 1 agonists
An agonist that binds to and activates piezo1 receptors.
piezo type mechanosensitive ion channel component 1 agonist
piezo type mechanosensitive ion channel component 1 agonists
piezo-type mechanosensitive ion channel component 1 agonist
piezo-type mechanosensitive ion channel component 1 agonists
mitochondrial calcium uniporter inhibitor
Any inhibitor of mitochondrial calcium uniporter.
mitochondrial calcium uniporter blockers
mitochondrial calcium uniporter inhibitors
gastric inhibitory polypeptide receptor agonist
An agonist that binds to and activates gastric inhibitory polypeptide (GIP) receptors.
gastric inhibitory polypeptide receptor agonists
glucose-dependent insulinotropic polypeptide receptor agonist
glucose-dependent insulinotropic polypeptide receptor agonists
Any agent that interferes with the activity of T-type calcium channels.
A class of diuretics which promote aquaresis (the excretion of water without electrolyte loss).
An agonist that activates NOD1 receptors.
caspase recruitment domain-containing protein 4 agonist
caspase recruitment domain-containing protein 4 agonists
nucleotide binding oligomerization domain containing 1 agonist
nucleotide binding oligomerization domain containing 1 agonists
nucleotide-binding oligomerization domain-containing protein 1 agonist
nucleotide-binding oligomerization domain-containing protein 1 agonists
A substance that increases the rate of a chemical reaction.
An activator of an enzyme-catalysed reaction.
EC 2.6.1.13 (ornithine aminotransferase) inhibitor
An EC 2.6.1.* (transaminase) inhibitor that interferes with the action of ornithine aminotransferase (EC 2.6.1.13).
EC 2.6.1.13 (ornithine aminotransferase) inhibitors
L-ornithine 5-aminotransferase inhibitor
L-ornithine 5-aminotransferase inhibitors
L-ornithine:alpha-ketoglutarate -aminotransferase inhibitor
L-ornithine:alpha-ketoglutarate -aminotransferase inhibitors
ornithine--oxo-acid transaminase inhibitor
ornithine--oxo-acid transaminase inhibitors
ornithine-2-oxoacid aminotransferase inhibitor
ornithine-2-oxoacid aminotransferase inhibitors
ornithine-alpha-ketoglutarate aminotransferase inhibitor
ornithine-alpha-ketoglutarate aminotransferase inhibitors
ornithine-keto acid aminotransferase inhibitor
ornithine-keto acid aminotransferase inhibitors
ornithine-keto acid transaminase inhibitor
ornithine-keto acid transaminase inhibitors
ornithine-ketoglutarate aminotransferase inhibitor
ornithine-ketoglutarate aminotransferase inhibitors
ornithine-oxo acid aminotransferase inhibitor
ornithine-oxo acid aminotransferase inhibitors
ornithine:alpha-oxoglutarate transaminase inhibitor
ornithine:alpha-oxoglutarate transaminase inhibitors
insulin-like growth factor-binding protein inhibitor
Any inhibitor that acts on insulin-like growth factor-binding proteins.
insulin-like growth factor-binding protein inhibitors
EC 2.7.12.1 (dual-specificity kinase) inhibitor
An EC 2.7.12.* [dual-specificity kinases (those acting on Ser/Thr and Tyr residues)] inhibitor that inhibits the action of dual-specificity kinase (EC 2.7.12.1).
Arabidopsis dual specificity kinase 1 inhibitor
Arabidopsis dual specificity kinase 1 inhibitors
EC 2.7.12.1 (dual-specificity kinase) inhibitors
An inhibitor that interferes with the action of PCNA.
proliferating cell nuclear antigen inhibitor
proliferating cell nuclear antigen inhibitors
sphingosine-1-phosphate receptor 2 antagonist
Any sphingosine-1-phosphate receptor (S1PR) antagonist that acts as an antagonist for the subtype 2 receptors (S1PR2).
sphingosine-1-phosphate receptor 2 antagonists
An EC 3.5.3.* (non-peptide linear amidine C-N hydrolase) inhibitor that interferes with the action of arginase (EC 3.5.3.1).
EC 3.5.3.* (non-peptide linear amidine C-N hydrolase) inhibitor
An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide linear amidine C-N hydrolase (EC 3.5.3.*).
EC 3.5.3.* (non-peptide linear amidine C-N hydrolase) inhibitors
non-peptide linear amidine C-N hydrolase (EC 3.5.3.*) inhibitor
non-peptide linear amidine C-N hydrolase (EC 3.5.3.*) inhibitors
calcitonin gene-related peptide receptor antagonist
An antagonist at any calcitonin gene-related peptide receptor.
calcitonin gene-related peptide receptor antagonists
Ras-related C3 botulinum toxin substrate 1 inhibitor
Ras-related C3 botulinum toxin substrate 1 inhibitors
A solvent used in nuclear magnetic resonance (NMR) spectroscopy.
EC 2.5.1.19 (3-phosphoshikimate 1-carboxyvinyltransferase) inhibitor
3-enol-pyruvoylshikimate-5-phosphate synthase inhibitor
3-enol-pyruvoylshikimate-5-phosphate synthase inhibitors
3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) inhibitor
3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) inhibitors
3-phosphoshikimate 1-carboxyvinyltransferase inhibitor
3-phosphoshikimate 1-carboxyvinyltransferase inhibitors
5-enolpyruvylshikimate-3-phosphate synthase inhibitor
5-enolpyruvylshikimate-3-phosphate synthase inhibitors
An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19).
EC 2.5.1.19 (3-phosphoshikimate 1-carboxyvinyltransferase) inhibitors
phosphoenolpyruvate:3-phosphoshikimate 5-O-(1-carboxyvinyl)-transferase inhibitor
phosphoenolpyruvate:3-phosphoshikimate 5-O-(1-carboxyvinyl)-transferase inhibitors
A mitochondrial respiratory-chain inhibitor that interferes with the action of ATP synthase.
A substance used to destroy pests of the subclass Acari (mites and ticks).
EC 2.2.1.6 (acetolactate synthase) inhibitor
An EC 2.2.1.* (transketolase/transaldolase) inhibitor that interferes with the action of acetolactate synthase (EC 2.2.1.6).
EC 2.2.1.6 (acetolactate synthase) inhibitors
acetolactate pyruvate-lyase (carboxylating) inhibitor
acetolactate pyruvate-lyase (carboxylating) inhibitors
acetolactate synthase (EC 2.2.1.6) inhibitor
acetolactate synthase (EC 2.2.1.6) inhibitors
alpha-acetohydroxy acid synthetase inhibitor
alpha-acetohydroxy acid synthetase inhibitors
alpha-acetohydroxyacid synthase inhibitor
alpha-acetohydroxyacid synthase inhibitors
alpha-acetolactate synthetase inhibitors
pyruvate:pyruvate acetaldehydetransferase (decarboxylating) inhibitor
pyruvate:pyruvate acetaldehydetransferase (decarboxylating) inhibitors
Highly reactive chemical that introduces alkyl radicals into biologically active molecules and thereby prevents their proper functioning. It could be used as an antineoplastic agent, but it might be very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. It could also be used as a component of poison gases.
alpha-1-microglobulin-Ig alpha complex chromophores
A substance that prevents pests from feeding.
A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides.
A substance that destroys or inhibits replication of viruses.
Any of a group of compounds, both naturally occurring and synthetic, that induce cell elongation in plant stems (from Greek alphaupsilonxialphanuomega, "to grow").
A molecular entity having an available pair of electrons capable of forming a covalent bond with a hydron (Bronsted base) or with the vacant orbital of some other molecular entity (Lewis base).
complement component 3a receptor 1 antagonist
complement component 3a receptor 1 antagonists
A sigma receptor modulator that activates the sigma-1 receptor.
Benzoic acid, 2-phenoxy-, 2-[(5-methyl-2-furanyl)methylene]hydrazide
beta-catenin - TCF interaction inhibitor
EC 2.1.1.354 ([histone H3]-lysine(4) N-trimethyltransferase) inhibitor
An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of [histone H3]-lysine(4) N-trimethyltransferase (EC 2.1.1.354).
EC 2.1.1.354 ([histone H3]-lysine(4) N-trimethyltransferase) inhibitors
[histone H3]-lysine(4) N-trimethyltransferase inhibitor
[histone H3]-lysine(4) N-trimethyltransferase inhibitors
A substance that inhibits any of the WNK signalling pathway.
lysine deficient protein kinase (WNK) signaling inhibitor
lysine deficient protein kinase (WNK) signaling inhibitors
with no lysine [K] (WNK) pathway inhibitor
with no lysine [K] (WNK) pathway inhibitors
with-no-lysine (WNK) protein kinase signaling inhibitor
with-no-lysine (WNK) protein kinase signaling inhibitors
trace amine-associated receptor 1 agonist
An agonist that selectively binds to and activates trace amine-associated receptor 1.
trace amine associated receptor 1 agonist
trace amine associated receptor 1 agonists
trace amine-associated receptor 1 agonists
Any compound that produces a peak used as reference frequency in the delta chemical shift scale.
Any inhibitor that interferes with the action of heat shock factor 1.
An insecticide compound naturally occurring in plants.
sodium-glucose transport protein subtype 1 inhibitor
Any inhibitor that interferes with the action of sodium-glucose transport protein subtype 1.
sodium glucose co-transporter 1 inhibitor
sodium glucose co-transporter 1 inhibitors
sodium-glucose transport protein subtype 1 inhibitors
sodium/glucose cotransporter 1 inhibitor
sodium/glucose cotransporter 1 inhibitors
solute carrier family 5 member 1 inhibitor
solute carrier family 5 member 1 inhibitors
EC 2.7.1.153 (phosphatidylinositol-4,5-bisphosphate 3-kinase) inhibitor
ATP:1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 3-phosphotransferase inhibitor
ATP:1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 3-phosphotransferase inhibitors
Any EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor that interferes with the action of phosphatidylinositol-4,5-bisphosphate 3-kinase (EC 2.7.1.153).
phosphatidylinositol-4,5-bisphosphate 3-kinase inhibitor
phosphatidylinositol-4,5-bisphosphate 3-kinase inhibitors
type I phosphoinositide 3-kinase inhibitor
type I phosphoinositide 3-kinase inhibitors
Any inhibitor of complement component 5.
An antagonist of the inhibitor of apoptosis proteins. Inhibitors of apoptosis proteins (IAP) are a family of functionally and structurally related proteins that serve as endogenous inhibitors of programmed cell death (apoptosis).
inhibitor of apoptosis protein antagonist
inhibitor of apoptosis protein antagonists
chromosomal region maintenance 1 inhibitor
chromosomal region maintenance 1 inhibitors
Any substance that inhibits the action of glucose transporters.
Any glucose transporter inhibitor that interferes with the action of glucose transporter 1.
solute carrier family 2, facilitated glucose transporter member 1 inhibitor
solute carrier family 2, facilitated glucose transporter member 1 inhibitors
EC 4.2.1.1 (carbonic anhydrase) inhibitor
An EC 4.2.1.* (hydro-lyases) inhibitor that interferes with the action of carbonic anhydrase (EC 4.2.1.1). Such compounds reduce the secretion of H(+) ions by the proximal kidney tubule.
EC 4.2.1.1 (carbonic anhydrase) inhibitors
carbonate hydro-lyase (carbon-dioxide-forming) inhibitor
carbonate hydro-lyase (carbon-dioxide-forming) inhibitors
carbonic anhydrase (EC 4.2.1.1) inhibitor
carbonic anhydrase (EC 4.2.1.1) inhibitors
EC 2.4.1.34 (1,3-beta-glucan synthase) inhibitor
(1,3)-beta-glucan (callose) synthase inhibitor
(1,3)-beta-glucan (callose) synthase inhibitors
1,3-beta-D-glucan--UDP glucosyltransferase inhibitor
1,3-beta-D-glucan--UDP glucosyltransferase inhibitors
1,3-beta-D-glucan-UDP glucosyltransferase inhibitor
1,3-beta-D-glucan-UDP glucosyltransferase inhibitors
1,3-beta-glucan-uridine diphosphoglucosyltransferase inhibitor
1,3-beta-glucan-uridine diphosphoglucosyltransferase inhibitors
A EC 2.4.1.* (hexosyltransferase) inhibitor that inhibits the action of 1,3-beta-glucan synthase (EC 2.4.1.34).
EC 2.4.1.34 (1,3-beta-glucan synthase) inhibitors
UDP-glucose--1,3-beta-D-glucan glucosyltransferase inhibitor
UDP-glucose--1,3-beta-D-glucan glucosyltransferase inhibitors
UDP-glucose-1,3-beta-D-glucan glucosyltransferase inhibitor
UDP-glucose-1,3-beta-D-glucan glucosyltransferase inhibitors
UDP-glucose-1,3-beta-glucan glucosyltransferase inhibitor
UDP-glucose-1,3-beta-glucan glucosyltransferase inhibitors
UDP-glucose-beta-glucan glucosyltransferase inhibitor
UDP-glucose-beta-glucan glucosyltransferase inhibitors
UDP-glucose:(1,3)beta-glucan synthase inhibitor
UDP-glucose:(1,3)beta-glucan synthase inhibitors
UDP-glucose:1,3-beta-D-glucan 3-beta-D-glucosyltransferase inhibitor
UDP-glucose:1,3-beta-D-glucan 3-beta-D-glucosyltransferase inhibitors
uridine diphosphoglucose-1,3-beta-glucan glucosyltransferase inhibitor
uridine diphosphoglucose-1,3-beta-glucan glucosyltransferase inhibitors
A substance intended to sterilize any organism.
EC 2.4.2.12 (nicotinamide phosphoribosyltransferase) inhibitor
An EC 2.4.2.* (pentosyltransferase) inhibitor that interferes with the action of nicotinamide phosphoribosyltransferase (EC 2.4.2.12).
EC 2.4.2.12 (nicotinamide phosphoribosyltransferase) inhibitor inhibitors
nicotinamide mononucleotide pyrophosphorylase inhibitor
nicotinamide mononucleotide pyrophosphorylase inhibitors
nicotinamide mononucleotide synthetase inhibitor
nicotinamide mononucleotide synthetase inhibitors
nicotinamide phosphoribosyltransferase inhibitor
nicotinamide phosphoribosyltransferase inhibitors
nicotinamide-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase inhibitor
nicotinamide-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase inhibitors
Bromo- and Extra-Terminal domain inhibitor
Bromo- and Extra-Terminal domain inhibitors
interleukin 8 receptor, beta antagonists
EC 1.3.1.6 (fumarate reductase (NADH)) inhibitor
An EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of fumarate reductase (NADH) (EC 1.3.1.6).
EC 1.3.1.6 (fumarate reductase (NADH)) inhibitors
NADH-dependent fumarate reductase inhibitor
NADH-dependent fumarate reductase inhibitors
A drug that induces seizures or increases their severity.
Any compound that is able to prevent damage to the kidneys.
NACHT, LRR and PYD domains-containing protein 3 inhibitor
NACHT, LRR and PYD domains-containing protein 3 inhibitors
NLR family pyrin domain containing 3 inhibitor
NLR family pyrin domain containing 3 inhibitors
PYRIN-containing APAF1-like protein 1 inhibitor
PYRIN-containing APAF1-like protein 1 inhibitors
1-cyclopropyl-6,8-difluoro-7-(4-hydroxyphenyl)-4-oxoquinoline-3-carboxylic acid
bathophenanthrolinedisulfonic acid disodium salt
bathophenanthrolinedisulfonic acid disodium salt hydrate
cyclohexylmethyl-[(2S)-3-[[(1S)-1-(3,4-dichlorophenyl)ethyl]amino]-2-hydroxypropyl]phosphinic acid
The part (atom or group of atoms) of a molecular entity in which the electronic transition responsible for a given spectral band is approximately localized.
5-(5-(7-(Trifluoromethyl)quinolin-4-ylthio)pentyloxy)-2-(morpholinomethyl)-4H-pyran-4-one dihydrochloride
A chelator that is any compound containing a ligand (typically organic) which is able to form a bond to a central calcium atom at two or more points.
Any product obtained as a result of mass spectrometer degradation.
G protein-coupled receptor 105 antagonist
G protein-coupled receptor 105 antagonists
EC 1.14.11.68 ([histone H3]-trimethyl-L-lysine(27) demethylase) inhibitor
An EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor that interferes with the action of [histone H3]-trimethyl-L-lysine(27) demethylase (EC 1.14.11.68).
EC 1.14.11.68 ([histone H3]-trimethyl-L-lysine(27) demethylase) inhibitors
[histone H3]-N(6),N(6),N(6)-trimethyl-L-lysine-27,2-oxoglutarate:oxygen oxidoreductase inhibitor
[histone H3]-N(6),N(6),N(6)-trimethyl-L-lysine-27,2-oxoglutarate:oxygen oxidoreductase inhibitors
[histone H3]-trimethyl-L-lysine(27) demethylase inhibitor
[histone H3]-trimethyl-L-lysine(27) demethylase inhibitors
Any agent which acts to reduce fibrosis.
Any compound that can sensitise tumour cells to chemotherapy.
A low-molecular-weight, non-protein organic compound participating in enzymatic reactions as dissociable acceptor or donor of chemical groups or electrons.
An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group).
Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity.
EC 3.2.1.169 (protein O-GlcNAcase) inhibitor
An EC 3.2.1.* (glycosidase) inhibitor that interferes with the action of protein O-GlcNAcase (EC 3.2.1.169).
EC 3.2.1.169 (protein O-GlcNAcase) inhibitors
[protein]-3-O-(N-acetyl-beta-D-glucosaminyl)-L-serine/threonine N-acetylglucosaminyl hydrolase inhibitor
[protein]-3-O-(N-acetyl-beta-D-glucosaminyl)-L-serine/threonine N-acetylglucosaminyl hydrolase inhibitors
glycoside hydrolase O-GlcNAcase inhibitor
glycoside hydrolase O-GlcNAcase inhibitors
oligodendrocyte lineage transcription factor 2 inhibitor
oligodendrocyte lineage transcription factor 2 inhibitors
oligodendrocyte transcription factor 2 inhibitor
oligodendrocyte transcription factor 2 inhibitors
oligodendrocyte transcription factor inhibitor
oligodendrocyte transcription factor inhibitors
A phytohormone that promote cell division, or cytokinesis, in plant roots and shoots.
A herbicide which when sprayed or dusted on plants causes its leaves to fall off.
Any substance which when absorbed into a living organism may modify one or more of its functions. The term is generally accepted for a substance taken for a therapeutic purpose, but is also commonly used for abused substances.
A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
A 3-hydroxy steroid that is estra-1,3,5(10)-triene substituted by hydroxy groups at positions 3 and 17.
Any vitamin that dissolves in fats and are stored in body tissues. Unlike the water-soluble vitamins, they are stored in the body for long periods of time and generally pose a greater risk for toxicity when consumed in excess.
A substance used to destroy fungal pests.
EC 6.3.1.2 (glutamate--ammonia ligase) inhibitor
An EC 6.3.* (C-N bond-forming ligase) inhibitor that interferes with the action of glutamate--ammonia ligase (EC 6.3.1.2).
EC 6.3.1.2 (glutamate--ammonia ligase) inhibitors
L-glutamate:ammonia ligase (ADP-forming) inhibitor
L-glutamate:ammonia ligase (ADP-forming) inhibitors
glutamate--ammonia ligase (EC 6.3.1.2) inhibitor
glutamate--ammonia ligase (EC 6.3.1.2) inhibitors
glutamylhydroxamic synthetase inhibitors
A role played by the molecular entity or part thereof within a biological context.
A substance used to destroy plant pests.
Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds.
A growth regulator that inhibits the life cycle of an insect.
Strictly, a substance intended to kill members of the class Insecta. In common usage, any substance used for preventing, destroying, repelling or controlling insects.
A role played by a chemical agent which exhibits the capability of occupying space between DNA base pairs due to particular properties in size, shape and charge. Intercalation of chemical compounds in DNA helix can result in replication errors (shift, mutation) or DNA damages.
A compound which can carry specific ions through membranes of cells or organelles.
Any ionophore capable of transportation of iron ions across membranes.
The jasmonates (JAs) are a group of plant hormones which help regulate plant growth and development.
A low-molecular-mass compound present in bioluminescent organisms that emits light when oxidized in presence of enzyme luciferase.
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
mitochondrial respiratory-chain inhibitor
mitochondrial electron transport chain inhibitors
mitochondrial electron-transport chain inhibitor
mitochondrial respiratory chain inhibitors
An agent that increases the frequency of mutations above the normal background level, usually by interacting directly with DNA and causing it damage, including base substitution.
A substance used to destroy pests of the phylum Nematoda (roundworms).
An endogenous compound that is used to transmit information across the synapse between a neuron and another cell.
A class of neuro-active insecticides that act at the nicotinic acetylcholine receptor.
A role played by signal molecules produced by the symbiotic bacteria that trigger nodule formation (typically on the host plant roots).
A solute used by a cell under water stress to maintain cell volume.
A substance that increases the efficacy of a pesticide.
Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests.
A semiochemical used in olfactory communication between organisms of the same species eliciting a change in sexual or social behaviour.
photosynthetic electron-transport chain inhibitor
A toxin made by a plant that acts against an organism attacking it.
An endogenous molecular entity that results in a colour of an organism as the consequence of the selective absorption of light.
A chemical, natural or artificial, that can affect the rate of growth of a plant.
A tightly bound, specific nonpolypeptide unit in a protein determining and involved in its biological activity.
A molecular messenger released by an organism that affects the behaviour within or between species.
Any of low-molecular-mass iron(III)-chelating compounds produced by microorganisms for the purpose of the transport and sequestration of iron.
A quinoline having a chloro group at the 7-position and an aryl amino group at the 4-position.
A synthetic compound exhibiting auxin activity.
systemic acquired resistance inducing compounds
Poisonous substance produced by a biological organism such as a microbe, animal or plant.
Any nutrient required in small quantities by organisms throughout their life in order to orchestrate a range of physiological functions.
Any plant metabolite that is found naturally as a component of a volatile oil.
Any vitamin that dissolves in water and readily absorbed into tissues for immediate use. Unlike the fat-soluble vitamins, they are not stored in the body and need to be replenished regularly in the diet and will rarely accumulate to toxic levels since they are quickly excreted from the body via urine.
A surfactant (or a mixture containing one or more surfactants) having cleaning properties in dilute solutions.
A cinchona alkaloid consisting of cinchonine with the hydrogen at the 6-position of the quinoline ring substituted by methoxy.
An aromatic ketone that is propiophenone carrying a tert-butylamino group at position 2 and a chloro substituent at position 3 on the phenyl ring.
A biochemical role played by any micronutrient that is an organic compound. Vitamins are present in foods in small amounts and are essential to normal metabolism and biochemical functions, usually as coenzymes. The term "vitamines" (from vita + amines) was coined in 1912 by Casimir Funk, who believed that these compounds were amines.
A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis.
Intended use of the molecular entity or part thereof by humans.
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
A substance (or active part thereof) that kills or slows the growth of bacteria.
A nutrient is a food component that an organism uses to survive and grow.
An agrochemical is a substance that is used in agriculture or horticulture.
A fertilizer is any substance that is added to soil or water to assist the growth of plants.
A substance used to destroy rodent pests.
A substance used to destroy bird pests (class Aves).
A physiological role played by any substance of either plant, animal or artificial origin which contains essential body nutrients that can be ingested by an organism to provide energy, promote growth, and maintain the processes of life.
An energy-rich substance that can be transformed with release of usable energy.
A substance administered to aid diagnosis of a disease.
A substance used in a chemical reaction to detect, measure, examine, or produce other substances.
A substance used to destroy pests of the phylum Mollusca.
Any nutrient required in large quantities by organisms throughout their life in order to orchestrate a range of physiological functions. Macronutrients are usually chemical elements (carbon, hydrogen, nitrogen, oxygen, phosphorus and sulfur) that humans consume in the largest quantities. Calcium, sodium, magnesium and potassium are sometimes included as macronutrients because they are required in relatively large quantities compared with other vitamins and minerals.
A substance which lowers the surface tension of the medium in which it is dissolved, and/or the interfacial tension with other phases, and, accordingly, is positively adsorbed at the liquid/vapour and/or at other interfaces.
A part of a molecular entity (atom or group of atoms) in which electronic excitation associated with a given emission band is approximately localized.
A role played by a foreign substance mixed with or attached to a given substance to enable the distribution or location of the latter to be determined subsequently.
A role played by a chemical compound with properties similar to those of the substance being traced with which it is mixed homogeneously.
A tracer which only differs in isotopic composition from the substance to be traced.
A tracer containing a radioactive label.
A physical tracer is one that is attached by physical means to the object being traced.
A role played by a part of a molecular entity distinguishable by the observer but not by the system and used to identify a tracer.
A role played by a stable paramagnetic group that is attached to a part of a molecular entity whose microscopic environment is of interest and may be revealed by the electron spin resonance (ESR) spectroscopy.
A substance which is structurally similar to a metabolite but which competes with it or replaces it, and so prevents or reduces its normal utilization.
A substance that diminishes the rate of a chemical reaction.
A substance that increases the rate of a reaction without modifying the overall standard Gibbs energy change in the reaction.
A small molecule which increases (activator) or decreases (inhibitor) the activity of an (allosteric) enzyme by binding to the enzyme at the regulatory site (which is different from the substrate-binding catalytic site).
Any substance or mixture of substances that, in solution (typically aqueous), resists change in pH upon addition of small amounts of acid or base.
A role played by a stable paramagnetic molecular entity used to study the microscopic environment by electron paramagnetic resonance (EPR) spectroscopy without covalent attachment to the molecular entity of interest.
A fuel such as coal, oil and natural gas which has formed over many years through the decomposition of deposited vegetation which was under extreme pressure of an overburden of earth.
Material containing fissile nuclides, which when placed in a reactor, enables a chain reaction to be achieved.
Any pharmaceutical compound containing a radioisotope.
Any drug that enhances the activity of the central nervous system.
A substance used in the prophylaxis or therapy of infectious diseases.
A substance used to treat or prevent parasitic infections.
Substance intended to kill parasitic worms (helminths).
A substance used in the treatment or control of nematode infestations.
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor
An EC 3.4.15.* (peptidyl-dipeptidase) inhibitor that interferes with the action of peptidyl-dipeptidase A (EC 3.4.15.1).
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitors
angiotensin I-converting enzyme inhibitor
angiotensin I-converting enzyme inhibitors
angiotensin-converting enzyme inhibitors
dipeptidyl carboxypeptidase I inhibitors
endothelial cell peptidyl dipeptidase inhibitor
endothelial cell peptidyl dipeptidase inhibitors
peptidyl-dipeptidase A (EC 3.4.15.1) inhibitor
peptidyl-dipeptidase A (EC 3.4.15.1) inhibitors
Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.
A class of drugs producing both physiological and psychological effects through a variety of mechanisms involving the central nervous system.
A loosely defined grouping of drugs that have effects on psychological function.
A substance that reduces or suppresses inflammation.
A traditional grouping of drugs said to have a soothing or calming effect on mood, thought or behaviour.
Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions.
An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.
Antimanic drugs are agents used to treat bipolar disorders or mania associated with other affective disorders.
An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms.
A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
A narcotic or opioid substance, synthetic or semisynthetic agent producing profound analgesia, drowsiness, and changes in mood.
EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor
An EC 1.2.1.* (oxidoreductase acting on donor aldehyde/oxo group with NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of aldehyde dehydrogenase (NAD(+)), EC 1.2.1.3.
CoA-independent aldehyde dehydrogenase inhibitor
CoA-independent aldehyde dehydrogenase inhibitors
EC 1.2.1.3 (aldehyde dehydrogenase (NAD(+))) inhibitor
EC 1.2.1.3 (aldehyde dehydrogenase (NAD(+))) inhibitors
EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitors
NAD-dependent 4-hydroxynonenal dehydrogenase inhibitor
NAD-dependent 4-hydroxynonenal dehydrogenase inhibitors
NAD-dependent aldehyde dehydrogenase inhibitor
NAD-dependent aldehyde dehydrogenase inhibitors
NAD-linked aldehyde dehydrogenase inhibitor
NAD-linked aldehyde dehydrogenase inhibitors
aldehyde dehydrogenase (NAD(+)) (EC 1.2.1.3) inhibitor
aldehyde dehydrogenase (NAD(+)) (EC 1.2.1.3) inhibitors
aldehyde dehydrogenase (NAD(+)) inhibitor
aldehyde dehydrogenase (NAD(+)) inhibitors
m-methylbenzaldehyde dehydrogenase inhibitor
m-methylbenzaldehyde dehydrogenase inhibitors
propionaldehyde dehydrogenase inhibitors
A loosely defined group of drugs that tend to reduce the activity of the central nervous system.
A drug that prevents or reduces fever by lowering the body temperature from a raised state. An antipyretic will not affect the normal body temperature if one does not have fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever.
A compound which inhibits or antagonises the biosynthesis or actions of androgens.
An agent that promotes the excretion of urine through its effects on kidney function.
Drugs capable of inducing illusions, hallucinations, delusions, paranoid ideations and other alterations of mood and thinking.
An agent that selectively binds to and activates beta-adrenergic receptors.
An agent that causes an increase in the expansion of a bronchus or bronchial tubes.
A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.
A drug which lowers the blood glucose level.
An agent that binds to but does not activate beta-adrenergic receptors thereby blocking the actions of endogenous or exogenous beta-adrenergic agonists. beta-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety.
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor
(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate,hydrogen-donor:oxygen oxidoreductase inhibitor
(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate,hydrogen-donor:oxygen oxidoreductase inhibitors
A compound or agent that combines with cyclooxygenases (EC 1.14.99.1) and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of icosanoids, prostaglandins, and thromboxanes.
EC 1.14.99.1 (cyclooxygenase) inhibitors
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitors
cyclooxygenase (EC 1.14.99.1) inhibitors
prostaglandin endoperoxide synthetase inhibitor
prostaglandin endoperoxide synthetase inhibitors
A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume.
An agent that selectively binds to and activates alpha-adrenergic receptors.
EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor
An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor which interferes with the activity of the enzyme protein tyrosine phosphatases (PTPs), EC 3.1.3.48, involved in the removal of phosphate groups from phosphorylated tyrosine residues on proteins.
EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitors
[phosphotyrosine]protein phosphatase inhibitor
[phosphotyrosine]protein phosphatase inhibitors
phosphoprotein phosphatase (phosphotyrosine) inhibitor
phosphoprotein phosphatase (phosphotyrosine) inhibitors
phosphotyrosine histone phosphatase inhibitor
phosphotyrosine histone phosphatase inhibitors
phosphotyrosine protein phosphatase inhibitor
phosphotyrosine protein phosphatase inhibitors
phosphotyrosylprotein phosphatase inhibitor
phosphotyrosylprotein phosphatase inhibitors
protein phosphotyrosine phosphatase inhibitor
protein phosphotyrosine phosphatase inhibitors
protein-tyrosine-phosphatase (EC 3.1.3.48) inhibitor
protein-tyrosine-phosphatase (EC 3.1.3.48) inhibitors
protein-tyrosine-phosphate phosphohydrolase inhibitor
protein-tyrosine-phosphate phosphohydrolase inhibitors
tyrosine O-phosphate phosphatase inhibitor
tyrosine O-phosphate phosphatase inhibitors
A substance that inhibits or prevents the proliferation of neoplasms.
A food additive that is used to added improve the taste or odour of a food.
A drug used to cause dilation of the blood vessels.
A drug used to prevent seizures or reduce their severity.
An EC 3.5.2.* (non-peptide cyclic amide C-N hydrolase) inhibitor that interferes with the action of beta-lactamase (EC 3.5.2.6).
penicillin amido-beta-lactamhydrolase inhibitor
penicillin amido-beta-lactamhydrolase inhibitors
EC 1.17.3.2 (xanthine oxidase) inhibitor
An EC 1.17.3.* (oxidoreductase acting on CH or CH2 with oxygen as acceptor) inhibitor that interferes with the action of xanthine oxidase (EC 1.17.3.2).
EC 1.17.3.2 (xanthine oxidase) inhibitors
hypoxanthine-xanthine oxidase inhibitors
hypoxanthine:oxygen oxidoreductase inhibitor
hypoxanthine:oxygen oxidoreductase inhibitors
xanthine oxidase (EC 1.17.3.2) inhibitor
xanthine oxidase (EC 1.17.3.2) inhibitors
xanthine:oxygen oxidoreductase inhibitor
xanthine:oxygen oxidoreductase inhibitors
Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin.
An inhibitor of HIV protease, an enzyme required for production of proteins needed for viral assembly.
EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor
Any EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that inhibits HMG-CoA reductases. Hydroxymethylglutaryl-CoA reductase inhibitors have been shown to lower directly cholesterol synthesis. The Enzyme Commission designation is EC 1.1.1.34 for the NADPH-dependent enzyme and EC 1.1.1.88 for an NADH-dependent enzyme.
hydroxymethylglutaryl-CoA reductase inhibitor
hydroxymethylglutaryl-CoA reductase inhibitors
Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
A drug that binds to and activates histamine receptors. Although they have been suggested for a variety of clinical applications, histamine agonists have so far been more widely used in research than therapeutically.
A substance used to treat hyperlipidemia (an excess of lipids in the blood).
An agent used to treat cestode, trematode, or other flatworm infestations in man or animals.
A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means.
An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.
An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.
A substance that suppresses Mycobacterium leprae, ameliorates the clinical manifestations of leprosy, and/or reduces the incidence and severity of leprous reactions.
An agent useful in the treatment or prevention of coccidiosis in man or animals.
Any antimicrobial drug which is used to treat or prevent protozoal infections.
A substance used to lower plasma cholesterol levels.
A gout suppressant that acts directly on the renal tubule to increase the excretion of uric acid, thus reducing its concentrations in plasma.
A drug used to treat rheumatoid arthritis.
A drug that increases uric acid excretion by the kidney (uricosuric drug), decreases uric acid production (antihyperuricemic), or alleviates the pain and inflammation of acute attacks of gout.
A drug used for its effect on the kidneys' regulation of body fluid composition and volume.
A compound or agent that combines with lipoxygenase and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of the icosanoid products hydroxyicosatetraenoic acid and various leukotrienes.
An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders.
A substance used for its pharmacological action on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function.
A drug used to treat or prevent microbial infections.
A substance used in the prophylaxis or therapy of virus diseases.
A drug used to treat or prevent bacterial infections.
A drug used in the treatment of infections with bacteria of the genus Treponema.
A substance that is used in the treatment of syphilis.
A drug used to treat infestations with arthropods of the subclass Acari (mites and ticks).
A drug that stimulates contraction of the myometrium. Oxytocics are used to induce labour, obstetric at term, to prevent or control postpartum or postabortion haemorrhage, and to assess foetal status in high risk pregnancies. They may also be used alone or with other drugs to induce abortions (abortifacients).
An organosulfonate oxoanion that is the conjugate base of taurocholic acid.
Any member of a group of drugs that reversibly inhibit the propagation of signals along nerves. Wide variations in potency, stability, toxicity, water-solubility and duration of action determine the route used for administration, e.g. topical, intravenous, epidural or spinal block.
A drug used to treat or prevent infections caused by protozoal organisms belonging to the suborder Trypanosomatida.
A compound which stimulates anabolism and inhibits catabolism. Anabolic agents stimulate the development of muscle mass, strength, and power.
An agent that promotes the production and release of interferons.
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor
3-hydroxy 3-methylglutaryl coenzymeA reductase phosphatase inhibitor
3-hydroxy 3-methylglutaryl coenzymeA reductase phosphatase inhibitors
Any EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of phosphoprotein phosphatase (EC 3.1.3.16).
Aspergillus awamori acid protein phosphatase inhibitor
Aspergillus awamori acid protein phosphatase inhibitors
EC 3.1.3.16 (protein serine/threonine phosphatase) inhibitors
HMG-CoA reductase phosphatase inhibitors
branched-chain alpha-keto acid dehydrogenase phosphatase inhibitor
branched-chain alpha-keto acid dehydrogenase phosphatase inhibitors
phosphoprotein phosphatase (EC 3.1.3.16) inhibitor
phosphoprotein phosphatase (EC 3.1.3.16) inhibitors
phosphoprotein phosphohydrolase inhibitor
phosphoprotein phosphohydrolase inhibitors
phosphopyruvate dehydrogenase phosphatase inhibitor
phosphopyruvate dehydrogenase phosphatase inhibitors
polycation modulated (PCM-) phosphatase inhibitor
polycation modulated (PCM-) phosphatase inhibitors
protein serine/threonine phosphatase (EC 3.1.3.16) inhibitors
protein serine/threonine phosphatase inhibitor
protein serine/threonine phosphatase inhibitors
serine/threonine specific protein phosphatase inhibitor
serine/threonine specific protein phosphatase inhibitors
A substance administered to enhance contrast in images of the inside of the body obtained using X-rays, gamma-rays, sound waves, radio waves (MRI), or radioactive particles in order to diagnose disease.
A substance having the property of absorbing, and therefore being opaque to, electromagnetic radiation, particularly X-rays.
An EC 2.7.7.* (nucleotidyltransferase) inhibitor that interferes with the action of RNA polymerase (EC 2.7.7.6).
C ribonucleic acid formation factors inhibitor
C ribonucleic acid formation factors inhibitors
DNA-dependent RNA nucleotidyltransferase inhibitor
DNA-dependent RNA nucleotidyltransferase inhibitors
DNA-dependent ribonucleate nucleotidyltransferase inhibitor
DNA-dependent ribonucleate nucleotidyltransferase inhibitors
DNA-directed nucleoside-triphosphate:RNA nucleotidyltransferase inhibitor
DNA-directed nucleoside-triphosphate:RNA nucleotidyltransferase inhibitors
RNA nucleotidyltransferase (DNA-directed) inhibitor
RNA nucleotidyltransferase (DNA-directed) inhibitors
deoxyribonucleic acid-dependent ribonucleic acid polymerase inhibitor
deoxyribonucleic acid-dependent ribonucleic acid polymerase inhibitors
nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed) inhibitor
nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed) inhibitors
ribonucleate nucleotidyltransferase inhibitor
ribonucleate nucleotidyltransferase inhibitors
ribonucleic acid nucleotidyltransferase inhibitor
ribonucleic acid nucleotidyltransferase inhibitors
ribonucleic acid transcriptase inhibitor
ribonucleic acid transcriptase inhibitors
An acid is a molecular entity capable of donating a hydron (Bronsted acid) or capable of forming a covalent bond with an electron pair (Lewis acid).
A compound which inhibits or antagonizes the biosynthesis or actions of proteases (endopeptidases).
An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of protein kinases.
EC 2.7.11.13 (protein kinase C) inhibitor
ATP:protein phosphotransferase (diacylglycerol-dependent) inhibitor
ATP:protein phosphotransferase (diacylglycerol-dependent) inhibitors
An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of protein kinase C (EC 2.7.11.13).
EC 2.7.11.13 (protein kinase C) inhibitors
calcium-dependent protein kinase C inhibitor
calcium-dependent protein kinase C inhibitors
calcium-independent protein kinase C inhibitor
calcium-independent protein kinase C inhibitors
calcium/phospholipid dependent protein kinase inhibitor
calcium/phospholipid dependent protein kinase inhibitors
protein kinase C (EC 2.7.11.13) inhibitor
protein kinase C (EC 2.7.11.13) inhibitors
An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of cholinesterase (EC 3.1.1.8).
choline esterase II (unspecific) inhibitor
choline esterase II (unspecific) inhibitors
A hormone that specifically regulates growth.
A plant growth regulator that modulates the formation of stems, leaves and flowers, as well as the development and ripening of fruit. The term includes endogenous and non-endogenous compounds (e.g. active compounds produced by bacteria on the leaf surface) as well as semi-synthetic and fully synthetic compounds.
An agent that selectively binds to and activates adrenergic receptors.
An agent that binds to but does not activate adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists.
An agent that binds to but does not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous alpha-adrenergic agonists. alpha-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.
H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists.
Drugs used for their actions on histaminergic systems.
H2-receptor antagonists are the drugs that selectively bind to but do not activate histamine H2 receptors, thereby blocking the actions of endogenous histamine.
Any agent that acts on an adrenergic receptor or affects the life cycle of an adrenergic transmitter.
A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human.
A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres.
A drug that has a strengthening effect on the heart or that can increase cardiac output.
Any of low-molecular-mass iron(III)-chelating compounds produced by plants for the purpose of the transport and sequestration of iron.
A ligand with two or more separate binding sites that can bind to a single metallic central atom, forming a chelate.
One of a class of drugs that acts by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools.
EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor
4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) inhibitor
4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) inhibitors
4-hydroxyphenylpyruvate dioxygenase inhibitor
4-hydroxyphenylpyruvate dioxygenase inhibitors
4-hydroxyphenylpyruvate hydroxylase inhibitor
4-hydroxyphenylpyruvate hydroxylase inhibitors
4-hydroxyphenylpyruvate:oxygen oxidoreductase (hydroxylating, decarboxylating) inhibitor
4-hydroxyphenylpyruvate:oxygen oxidoreductase (hydroxylating, decarboxylating) inhibitors
4-hydroxyphenylpyruvic acid dioxygenase inhibitor
4-hydroxyphenylpyruvic acid dioxygenase inhibitors
An EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 atoms of oxygen) inhibitor that interferes with the activity of 4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27).
EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitors
p-hydroxyphenylpyruvate dioxygenase inhibitor
p-hydroxyphenylpyruvate dioxygenase inhibitors
p-hydroxyphenylpyruvate hydroxylase inhibitor
p-hydroxyphenylpyruvate hydroxylase inhibitors
p-hydroxyphenylpyruvate oxidase inhibitor
p-hydroxyphenylpyruvate oxidase inhibitors
p-hydroxyphenylpyruvic acid hydroxylase inhibitor
p-hydroxyphenylpyruvic acid hydroxylase inhibitors
p-hydroxyphenylpyruvic hydroxylase inhibitor
p-hydroxyphenylpyruvic hydroxylase inhibitors
p-hydroxyphenylpyruvic oxidase inhibitor
p-hydroxyphenylpyruvic oxidase inhibitors
Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons.
Any drug that binds to and activates cholinergic receptors.
Any drug that binds to and activates a muscarinic cholinergic receptor.
muscarinic acetylcholine receptor agonist
Derivatives of carbamic acid with insecticidal properties of general formula ROC(=O)NR(1)R(2), where ROH is an alcohol, oxime, or phenol and R(1) is hydrogen or methyl. Like organophosphate insecticides, they are cholinesterase inhibitors, but carbamate insecticides differ in action from the organophosphates in that the inhibitory effect on cholinesterase is generally brief.
EC 3.1.1.7 (acetylcholinesterase) inhibitor
An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of enzyme acetylcholinesterase (EC 3.1.1.7), which helps breaking down of acetylcholine into choline and acetic acid.
EC 3.1.1.7 (acetylcholinesterase) inhibitors
acetyl.beta-methylcholinesterase inhibitor
acetyl.beta-methylcholinesterase inhibitors
acetylcholine acetylhydrolase inhibitors
acetylcholinesterase (EC 3.1.1.7) inhibitor
acetylcholinesterase (EC 3.1.1.7) inhibitors
mitochondrial NADH:ubiquinone reductase inhibitor
mitochondrial NADH dehydrogenase inhibitor
mitochondrial cytochrome-bc1 complex inhibitor
EC 1.9.3.1 (cytochrome c oxidase) inhibitor
An EC 1.9.3.* (oxidoreductase acting on donor heme group, oxygen as acceptor) inhibitor that interferes with the action of cytochrome c oxidase (EC 1.9.3.1).
EC 1.9.3.1 (cytochrome c oxidase) inhibitors
complex IV (mitochondrial electron transport) inhibitor
complex IV (mitochondrial electron transport) inhibitors
cytochrome c oxidase (EC 1.9.3.1) inhibitor
cytochrome c oxidase (EC 1.9.3.1) inhibitors
ferrocytochrome-c:oxygen oxidoreductase inhibitor
ferrocytochrome-c:oxygen oxidoreductase inhibitors
mitochondrial cytochrome-c oxidase inhibitors
EC 1.6.5.3 [NADH:ubiquinone reductase (H(+)-translocating)] inhibitor
A respiratory-chain inhibitor that interferes with the action of the the enzyme NADH:ubiquinone reductase (H(+)-translocating), EC 1.6.5.3.
EC 1.6.5.3 (NADH:ubiquinone reductase (H(+)-translocating)) inhibitor
EC 1.6.5.3 (NADH:ubiquinone reductase (H(+)-translocating)) inhibitors
EC 1.6.5.3 [NADH:ubiquinone reductase (H(+)-translocating)] inhibitors
NADH dehydrogenase (ubiquinone) inhibitor
NADH dehydrogenase (ubiquinone) inhibitors
NADH-coenzyme Q oxidoreductase inhibitors
NADH-ubiquinone oxidoreductase inhibitor
NADH-ubiquinone oxidoreductase inhibitors
NADH2 dehydrogenase (ubiquinone) inhibitor
NADH:ubiquinone oxidoreductase complex inhibitor
NADH:ubiquinone oxidoreductase inhibitor
NADH:ubiquinone oxidoreductase inhibitors
NADH:ubiquinone reductase (H(+)-translocating) inhibitor
NADH:ubiquinone reductase (H(+)-translocating) inhibitors
NADH:ubiquinone reductase (H+-translocating) inhibitor
complex I (NADH:Q1 oxidoreductase) inhibitors
complex I (electron transport chain) inhibitors
complex I (mitochondrial electron transport) inhibitors
dihydronicotinamide adenine dinucleotide-coenzyme Q reductase inhibitor
mitochondrial electron transport complex 1 inhibitor
mitochondrial electron transport complex I inhibitor
mitochondrial electron transport complex I inhibitors
reduced nicotinamide adenine dinucleotide-coenzyme Q reductase inhibitor
reduced nicotinamide adenine dinucleotide-coenzyme Q reductase inhibitors
(3R,5S,6E)-7-(4-(4-fluorophenyl)-6-(1-methylethyl)-2-(ethyl(methylsulfonyl)amino)-5-pyrimidinyl)-3,5-dihydroxy-6-heptenoic acid
(3R,5S,6E)-7-{4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid
(3R,5S,6E)-7-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid
A dihydroxy monocarboxylic acid that is (6E)-7-{4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidin-5-yl} hept-6-enoic acid carrying two hydroxy substituents at positions 3 and 5 (the 3R,5S-diastereomer).
EC 1.4.3.4 (monoamine oxidase) inhibitor
An EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor that interferes with the action of monoamine oxidase (EC 1.4.3.4).
EC 1.4.3.4 (monoamine oxidase) inhibitors
amine oxidase (flavin-containing) inhibitor
amine oxidase (flavin-containing) inhibitors
amine:oxygen oxidoreductase (deaminating) (flavin-containing) inhibitor
amine:oxygen oxidoreductase (deaminating) (flavin-containing) inhibitors
amine:oxygen oxidoreductase (deaminating) inhibitor
amine:oxygen oxidoreductase (deaminating) inhibitors
monoamine oxidase (EC 1.4.3.4) inhibitor
monoamine oxidase (EC 1.4.3.4) inhibitors
monoamine:O2 oxidoreductase (deaminating) inhibitor
monoamine:O2 oxidoreductase (deaminating) inhibitors
Any agent that affects the transport of molecular entities across a biological membrane.
An agent that inhibits sodium influx through cell membranes.
Any sodium channel blocker that interferes with the activity of voltage-gated sodium channels.
voltage-dependent sodium channel blockers
Any protein kinase inhibitor that interferes with the action of tyrosine kinase.
Substance used to treat lice (genus Pediculus) infestation.
Agents that increase calcium influx into calcium channels of excitable tissues.
A membrane transport modulator that is able to regulate intracellular calcium levels.
ryanodine-sensitive calcium channel modulator
ryanodine-sensitive calcium-release channel modulator
A surfactant with an uncharged hydrophilic headgroup.
A substance that can carry oxygen to and carbon dioxide away from the tissues when introduced into the blood stream. Blood substitutes are used to replace hemoglobin in severe hemorrhage and also to perfuse isolated organs.
Substance which produces loss of feeling or sensation.
Substance that produces loss of consciousness.
Drugs that used to treat infestations by flukes (trematodes) of the genus Schistosoma.
Any member of a collection of zwitterionic buffer substances selected or devised for suitability in experimental biological systems according to a number of predetermined criteria. Named after Dr. Norman Good.
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
A molecular entity that is an electron-pair acceptor and therefore able to form a covalent bond with an electron-pair donor (Lewis base), thereby producing a Lewis adduct.
A molecular entity able to provide a pair of electrons and thus capable of forming a covalent bond with an electron-pair acceptor (Lewis acid), thereby producing a Lewis adduct.
A volatile or volatilizable chemical compound utilized for control of pests in buildings, soil, grain, as well as during processing of goods to be imported or exported to prevent transfer of exotic organisms.
Any chemical substance that inhibits the life-cycle of an organism.
homopteran inhibitor of chitin biosynthesis
lepidopteran inhibitor of chitin biosynthesis
A role played by a fluorescent molecular entity used to study the microscopic environment by fluorescence spectroscopy.
Any drug which can be used to prevent or alleviate glaucoma, a disease in which the optic nerve is damaged, resulting in progressive, irreversible loss of vision. It is often, though not always, associated with increased pressure of the fluid in the eye.
A 6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene in which the sterocenters at positions 4a, 10 and 10a have S-configuration. It is a prodrug of dextrorphan and used as an antitussive drug for suppressing cough.
A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
(3R,5R,6S,7R,8R,11R,12S,13R,14S,15S)-12-[(4-O-acetyl-2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)oxy]-14-{[2-O-acetyl-3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy}-5,7,8,11,13,15-hexamethyl-4,10-dioxo-1,9-dioxaspiro[2.13]hexadecan-6-yl acetate
A semi-synthetic macrolide antibiotic obtained by acetylation of the three free hydroxy groups of oleandomycin. Troleandomycin is only found in individuals that have taken the drug.
A member of the class of phenothiazines that is phenothiazine having a trifluoromethyl subsitituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at the N-10 position.
A liquid that can dissolve other substances (solutes) without any change in their chemical composition.
2-((2,6-dichlorophenyl)amino)benzeneacetic acid
2-[(2,6-dichlorophenyl)amino]benzeneacetic acid
A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
[2-(2,6-dichloroanilino)phenyl]acetic acid
{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid
Anything used in a scientific experiment to indicate the presence of a substance or quality, change in a body, etc.
A chemical compound that can be excited by light of a specific wavelength and subsequently transfer energy to a chosen reactant. This is commonly molecular oxygen within a cancer tissue, which is converted to (highly rective) singlet state oxygen. This rapidly reacts with any nearby biomolecules, ultimately killing the cancer cells.
nicotinic acetylcholine receptor agonist
An agonist that selectively binds to and activates a nicotinic acetylcholine receptor.
nicotinic acetylcholine receptor agonists
A compound, usually an anti-bacterial agent or a toxin, which inhibits the synthesis of a protein.
A substance used locally on humans and other animals to destroy harmful microorganisms or to inhibit their activity (cf. disinfectants, which destroy microorganisms found on non-living objects, and antibiotics, which can be transported through the lymphatic system to destroy bacteria within the body).
An antimicrobial agent that is applied to non-living objects to destroy harmful microorganisms or to inhibit their activity.
Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.
A substance, extract, or preparation for diffusing or imparting an agreeable or attractive smell.
An exogenous or endogenous compound which inhibits serine endopeptidases.
A solvent that is composed of polar molecules. Polar solvents can dissolve ionic compounds or ionisable covalent compounds.
A polar solvent that is capable of acting as a hydron (proton) donor.
A solvent with a comparatively high relative permittivity (or dielectric constant), greater than ca. 15, and a sizable permanent dipole moment, that cannot donate suitably labile hydrogen atoms to form strong hydrogen bonds.
Solvent that is capable of acting as a hydron (proton) acceptor.
Self-ionizing solvent possessing both characteristics of Bronsted acids and bases.
EC 2.1.1.6 (catechol O-methyltransferase) inhibitor
An EC 2.1.1.* (methyltransferase) inhibitor that interferes with the action of catechol O-methyltransferase (EC 2.1.1.6).
EC 2.1.1.6 (catechol O-methyltransferase) inhibitors
S-adenosyl-L-methionine:catechol O-methyltransferase inhibitor
S-adenosyl-L-methionine:catechol O-methyltransferase inhibitors
catechol O-methyltransferase (EC 2.1.1.6) inhibitor
catechol O-methyltransferase (EC 2.1.1.6) inhibitors
catecholamine O-methyltransferase inhibitor
catecholamine O-methyltransferase inhibitors
A drug used in the treatment of Parkinson's disease.
An agent and endogenous substances that antagonize or inhibit the development of new blood vessels.
A local anesthetic that is used to numb the surface of a body part.
A drug that it mimics the action of calcium on tissues.
Any drug that acts on an alpha-adrenergic receptor.
Any of the drugs that act on beta-adrenergic receptors.
EC 1.1.1.21 (aldehyde reductase) inhibitor
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of aldehyde reductase (EC 1.1.1.21).
EC 1.1.1.21 (aldehyde reductase) inhibitors
aldehyde reductase (EC 1.1.1.21) inhibitor
aldehyde reductase (EC 1.1.1.21) inhibitors
alditol:NAD(P)(+) 1-oxidoreductase inhibitor
alditol:NAD(P)(+) 1-oxidoreductase inhibitors
alditol:NADP(+) 1-oxidoreductase inhibitor
alditol:NADP(+) 1-oxidoreductase inhibitors
polyol dehydrogenase (NADP(+)) inhibitor
polyol dehydrogenase (NADP(+)) inhibitors
A drug used for its effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons.
A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
A role played by a substance that can react readily with, and thereby eliminate, radicals.
A modulator of gamma-secretase, one of the three endopeptidases that are specific for amyloid protein precursor and which have been identified based upon the region of the amyloid protein precursor which they cleave.
A drug that prevent fibrinolysis or lysis of a blood clot or thrombus.
A drug that affects the function of fibrin in blood coagulation.
Substance which binds to cell receptors normally responding to naturally occurring substances and which produces a response of its own.
Substance that attaches to and blocks cell receptors that normally bind naturally occurring substances.
Any drug that binds to but does not activate cholinergic receptors, thereby blocking the actions of acetylcholine or cholinergic agonists.
A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
muscarinic acetylcholine receptor antagonist
An antagonist at the nicotinic cholinergic receptor.
nicotinic acetylcholine receptor antagonist
nicotinic acetylcholine receptor antagonists
Metabolites of bile acids, four-ringed steroid acids formed along the cholesterol degradation pathway.
A chemical substance which inhibits the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites.
A compound that inhibits the action of prostaglandins.
A drug that acts principally at one or more sites within the peripheral neuroeffector systems, the autonomic system, and motor nerve-skeletal system.
A drug designed to prevent leukotriene synthesis or activity by blocking binding at the receptor level.
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor
ATP phosphohydrolase (H(+)/K(+)-exchanging) inhibitor
ATP phosphohydrolase (H(+)/K(+)-exchanging) inhibitors
An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that inhibits H(+)/K(+)-exchanging ATPase, EC 3.6.3.10. Such compounds are also known as proton pump inhibitors.
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitors
One of various classes of drugs with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract.
Any inhibitor of cholesterylester transfer protein (CETP), which transfers cholesterol from high density lipoproteins (HDL, the 'good' cholesterol-containing particles) to low or very low density lipoproteins (LDL or VLDL, the 'bad' cholesterol-containing particles). Inhibition of this process results in higher HDL levels and lower LDL levels. CETP inhibitors are under investigation as potential drugs to reduce the risk of arteriosclerotic vascular disease (atherosclerosis).
cholesteryl ester transfer protein inhibitor
A chemical substance that prevents or reduces the probability of conception.
A chemical substance or agent with contraceptive activity in females.
A compound, usually hormonal, taken orally in order to block ovulation and prevent the occurrence of pregnancy.
An oral contraceptive which owes its effectiveness to synthetic preparation.
An agent that binds to and activates excitatory amino acid receptors.
Any hormone that is responsible for controlling sexual characteristics and reproductive function.
A sex hormone that stimulates or controls the development and maintenance of masculine characteristics in vertebrates by binding to androgen receptors.
A hormone that stimulates or controls the development and maintenance of female sex characteristics in mammals by binding to oestrogen receptors. The oestrogens are named for their importance in the oestrous cycle. The oestrogens that occur naturally in the body, notably estrone, estradiol, estriol, and estetrol are steroids. Other compounds with oestrogenic activity are produced by plants (phytoestrogens) and fungi (mycoestrogens); synthetic compounds with oestrogenic activity are known as xenoestrogens.
Any compound that exhibits antagonist activity at the mu-opioid receptor
A drug which causes a narrowing of the lumen of a bronchus or bronchiole.
A drug that softens, separates, and causes desquamation of the cornified epithelium or horny layer of skin. Keratolytic drugs are used to expose mycelia of infecting fungi or to treat corns, warts, and certain other skin diseases.
A drug used to treat or prevent skin disorders or for the routine care of skin.
An enzyme inhibitor that interferes with the activity of cytochrome P450 involved in catalysis of organic substances.
A compound which inhibits the movement of an ion across an energy-transducing cell membrane.
Any pathway inhibitor that inhibits the synthesis of fatty acids.
A substance that can be converted into a vitamin by animal tissues.
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor
An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of a phosphoric diester hydrolase (EC 3.1.4.*).
EC 3.1.4.* (phosphoric diester hydrolase) inhibitors
phosphoric diester hydrolase (EC 3.1.4.*) inhibitor
phosphoric diester hydrolase (EC 3.1.4.*) inhibitors
A drug used to reverse the inactivation of cholinesterase caused by organophosphates or sulfonates.
Compound which restore enzymatic activity by removing an inhibitory group bound to the reactive site of the enzyme.
Any protective agent counteracting or neutralizing the action of poisons.
Drug that acts on blood and blood-forming organs and those that affect the hemostatic system.
A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.
Synthetic or natural substance which is given to prevent a disease or disorder or are used in the process of treating a disease or injury due to a poisonous agent.
A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
EC 1.1.1.1 (alcohol dehydrogenase) inhibitor
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of alcohol dehydrogenase (EC 1.1.1.1).
EC 1.1.1.1 (alcohol dehydrogenase) inhibitors
NAD-dependent alcohol dehydrogenase inhibitor
NAD-dependent alcohol dehydrogenase inhibitors
NAD-specific aromatic alcohol dehydrogenase inhibitor
NAD-specific aromatic alcohol dehydrogenase inhibitors
alcohol dehydrogenase (EC 1.1.1.1) inhibitor
alcohol dehydrogenase (EC 1.1.1.1) inhibitors
aliphatic alcohol dehydrogenase inhibitor
aliphatic alcohol dehydrogenase inhibitors
primary alcohol dehydrogenase inhibitors
A 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole that has S configuration at the sulfur atom. An inhibitor of gastric acid secretion, it is used (generally as its sodium or magnesium salt) for the treatment of gastro-oesophageal reflux disease, dyspepsia, peptic ulcer disease, and Zollinger-Ellison syndrome.
EC 5.99.1.2 (DNA topoisomerase) inhibitor
A topoisomerase inhibitor that inhibits the bacterial enzymes of the DNA topoisomerases, Type I class (EC 5.99.1.2) that catalyze ATP-independent breakage of one of the two strands of DNA, passage of the unbroken strand through the break, and rejoining of the broken strand. These bacterial enzymes reduce the topological stress in the DNA structure by relaxing negatively, but not positively, supercoiled DNA.
EC 5.99.1.2 (DNA topoisomerase) inhibitors
EC 5.99.1.2 (topoisomerase I) inhibitors
topoisomerase I (EC 5.99.1.2) inhibitors
Any cholinergic antagonist that inhibits the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the muscarinic antagonists.
EC 2.4.1.80 (ceramide glucosyltransferase) inhibitor
An EC 2.4.1.* (hexosyltransferase) inhibitor that interferes with the activity of ceramide glucosyltransferase (EC 2.4.1.80).
EC 2.4.1.80 (ceramide glucosyltransferase) inhibitors
UDP-glucose:N-acylsphingosine D-glucosyltransferase inhibitor
UDP-glucose:N-acylsphingosine D-glucosyltransferase inhibitors
UDP-glucose:ceramide glucosyltransferase inhibitor
UDP-glucose:ceramide glucosyltransferase inhibitors
ceramide glucosyltransferase (EC 2.4.1.80) inhibitor
ceramide glucosyltransferase (EC 2.4.1.80) inhibitors
ceramide:UDP-glucose glucosyltransferase inhibitor
ceramide:UDP-glucose glucosyltransferase inhibitors
ceramide:UDPGlc glucosyltransferase inhibitor
ceramide:UDPGlc glucosyltransferase inhibitors
uridine diphosphoglucose-ceramide glucosyltransferase inhibitor
uridine diphosphoglucose-ceramide glucosyltransferase inhibitors
EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor
An EC 1.6.5.* (oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor) inhibitor that interferes with the action of NAD(P)H dehydrogenase (quinone), EC 1.6.5.2.
EC 1.6.5.2 (NAD(P)H dehydrogenase (quinone)) inhibitor
EC 1.6.5.2 (NAD(P)H dehydrogenase (quinone)) inhibitors
EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitors
NAD(P)H dehydrogenase (quinone) (EC 1.6.5.2) inhibitor
NAD(P)H dehydrogenase (quinone) (EC 1.6.5.2) inhibitors
NAD(P)H dehydrogenase (quinone) inhibitor
NAD(P)H dehydrogenase (quinone) inhibitors
NAD(P)H-quinone dehydrogenase inhibitors
NAD(P)H-quinone oxidoreductase inhibitor
NAD(P)H-quinone oxidoreductase inhibitors
NAD(P)H2 dehydrogenase (quinone) inhibitor
NAD(P)H2 dehydrogenase (quinone) inhibitors
NAD(P)H: menadione oxidoreductase inhibitor
NAD(P)H: menadione oxidoreductase inhibitors
NAD(P)H:(quinone-acceptor)oxidoreductase inhibitor
NAD(P)H:(quinone-acceptor)oxidoreductase inhibitors
NAD(P)H:quinone oxidoreductase inhibitor
NAD(P)H:quinone oxidoreductase inhibitors
dehydrogenase, reduced nicotinamide adenine dinucleotide (phosphate, quinone) inhibitor
dehydrogenase, reduced nicotinamide adenine dinucleotide (phosphate, quinone) inhibitors
flavoprotein NAD(P)H-quinone reductase inhibitor
flavoprotein NAD(P)H-quinone reductase inhibitors
reduced NAD(P)H dehydrogenase inhibitors
reduced nicotinamide-adenine dinucleotide (phosphate) dehydrogenase inhibitor
reduced nicotinamide-adenine dinucleotide (phosphate) dehydrogenase inhibitors
viologen accepting pyridine nucleotide oxidoreductase inhibitor
viologen accepting pyridine nucleotide oxidoreductase inhibitors
A role played by a molecular entity used to study the microscopic environment.
An acid or base which exhibits a colour change on neutralization by the basic or acidic titrant at or near the equivalence point of a titration.
Anything used in a scientific experiment that gives a visual change to indicate the presence of a substance or quality, change in a body, etc.
A substance which is adsorbed or desorbed with concomitant colour change at or near the equivalence point of a titration.
A colour indicator that is colourless on one side of the transition interval.
A colour indicator that possesses a different colour on each side of the transition interval.
EC 1.6.3.1. [NAD(P)H oxidase (H2O2-forming)] inhibitor
An EC 1.6.3.* (oxidoreductase acting on NADH or NADPH with oxygen as acceptor) inhibitor that interferes with the action of NAD(P)H oxidase (H2O2-forming), EC 1.6.3.1.
EC 1.6.3.1. (NAD(P)H oxidase (H2O2-forming)) inhibitor
EC 1.6.3.1. (NAD(P)H oxidase (H2O2-forming)) inhibitors
EC 1.6.3.1. [NAD(P)H oxidase (H2O2-forming)] inhibitors
NAD(P)H oxidase (H2O2-forming) (EC 1.6.3.1) inhibitor
NAD(P)H oxidase (H2O2-forming) (EC 1.6.3.1) inhibitors
NAD(P)H oxidase (H2O2-forming) inhibitor
NAD(P)H oxidase (H2O2-forming) inhibitors
NAD(P)H:oxygen oxidoreductase (H2O2-forming) inhibitor
NAD(P)H:oxygen oxidoreductase (H2O2-forming) inhibitors
NAD(P)H:oxygen oxidoreductase inhibitors
A drug or agent which antagonizes or impairs any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
platelet glycoprotein-IIb/IIIa receptor antagonist
Antagonist of platelet surface glycoprotein-IIb/IIIa which has a key role in hemostasis and thrombosis such as platelet adhesion and aggregation.
glycoprotein-IIb/IIIa receptor antagonist
glycoprotein-IIb/IIIa receptor antagonists
platelet glycoprotein-IIb/IIIa receptor antagonists
EC 3.5.4.4 (adenosine deaminase) inhibitor
An EC 3.5.4.* (non-peptide cyclic amidine C-N hydrolase) inhibitor that interferes with the action of adenosine deaminase (EC 3.5.4.4).
EC 3.5.4.4 (adenosine deaminase) inhibitors
adenosine deaminase (EC 3.5.4.4) inhibitor
adenosine deaminase (EC 3.5.4.4) inhibitors
An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of phospholipase A2 (EC 3.1.1.4).
EC 3.1.1.4 (phospholipase A2) inhibitors
phosphatidylcholine 2-acylhydrolase inhibitor
phosphatidylcholine 2-acylhydrolase inhibitors
phospholipase A2 (EC 3.1.1.4) inhibitors
EC 2.5.1.15 (dihydropteroate synthase) inhibitor
(2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl-diphosphate:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase inhibitor
(2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl-diphosphate:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase inhibitors
2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine-diphosphate:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase inhibitor
2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine-diphosphate:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase inhibitors
7,8-dihydropteroate synthetase inhibitor
7,8-dihydropteroate synthetase inhibitors
7,8-dihydropteroic acid synthetase inhibitor
7,8-dihydropteroic acid synthetase inhibitors
An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of dihydropteroate synthase (EC 2.5.1.15), an enzyme that catalyzes the formation of dihydropteroate from p-aminobenzoic acid and dihydropteridine-hydroxymethyl-pyrophosphate.
EC 2.5.1.15 (dihydropteroate synthase) inhibitors
dihydropteroate diphosphorylase inhibitor
dihydropteroate diphosphorylase inhibitors
dihydropteroate pyrophosphorylase inhibitor
dihydropteroate pyrophosphorylase inhibitors
dihydropteroate synthase (EC 2.5.1.15) inhibitor
dihydropteroate synthase (EC 2.5.1.15) inhibitors
An agent that produces a soft formed stool, and relaxes and loosens the bowels, typically used over a protracted period, to relieve constipation. Compare with cathartic, which is a substance that accelerates defecation. A substances can be both a laxative and a cathartic.
Compound that increase urine volume by increasing the amount of osmotically active solute in the urine. It also increases the osmolarity of plasma.
Substance that sweeten food, beverages, medications, etc.
Any agent that is used to decrease appetite.
An agent that inhibits cell membrane glycoproteins that are selectively permeable to potassium ions.
Agent that dilates the pupil. Used in eye diseases and to facilitate eye examination. It may be either a sympathomimetic or parasympatholytic. The latter cause cycloplegia or paralysis of accommodation at high doses and may precipitate glaucoma.
Drug used to cause constriction of the blood vessels.
An agent, with unique chemical structure and biochemical requirements, which generates nitric oxide.
EC 3.1.4.17 (3',5'-cyclic-nucleotide phosphodiesterase) inhibitor
3',5'-cyclic nucleoside monophosphate phosphodiesterase inhibitor
3',5'-cyclic nucleoside monophosphate phosphodiesterase inhibitors
3',5'-cyclic-nucleotide 5'-nucleotidohydrolase inhibitor
3',5'-cyclic-nucleotide 5'-nucleotidohydrolase inhibitors
3',5'-cyclic-nucleotide phosphodiesterase inhibitor
3',5'-cyclic-nucleotide phosphodiesterase inhibitors
3',5'-cyclonucleotide phosphodiesterase inhibitor
3',5'-cyclonucleotide phosphodiesterase inhibitors
3',5'-nucleotide phosphodiesterase inhibitor
3',5'-nucleotide phosphodiesterase inhibitors
3': 5'-monophosphate phosphodiesterase (cyclic CMP) inhibitor
3': 5'-monophosphate phosphodiesterase (cyclic CMP) inhibitors
3':5'-cyclic nucleotide 5'-nucleotidohydrolase inhibitor
3':5'-cyclic nucleotide 5'-nucleotidohydrolase inhibitors
An EC 3.1.4.* (phosphoric diester hydrolase) inhibitor which interferes with the action of 3',5'-cyclic-nucleotide phosphodiesterase (EC 3.1.4.17).
EC 3.1.4.17 (3',5'-cyclic-nucleotide phosphodiesterase) inhibitors
cyclic 3',5'-mononucleotide phosphodiesterase inhibitor
cyclic 3',5'-mononucleotide phosphodiesterase inhibitors
cyclic 3',5'-nucleotide phosphodiesterase inhibitor
cyclic 3',5'-nucleotide phosphodiesterase inhibitors
cyclic 3',5'-phosphodiesterase inhibitor
cyclic 3',5'-phosphodiesterase inhibitors
cyclic 3',5-nucleotide monophosphate phosphodiesterase inhibitor
cyclic 3',5-nucleotide monophosphate phosphodiesterase inhibitors
cyclic nucleotide phosphodiesterase inhibitor
cyclic nucleotide phosphodiesterase inhibitors
cytidine 3':5'-monophosphate phosphodiesterase (cyclic CMP) inhibitor
cytidine 3':5'-monophosphate phosphodiesterase (cyclic CMP) inhibitors
nucleoside 3',5'-cyclic phosphate diesterase inhibitor
nucleoside 3',5'-cyclic phosphate diesterase inhibitors
nucleoside-3',5-monophosphate phosphodiesterase inhibitor
nucleoside-3',5-monophosphate phosphodiesterase inhibitors
1,4-alpha-D-glucan glucanohydrolase inhibitor
1,4-alpha-D-glucan glucanohydrolase inhibitors
4-alpha-D-glucan glucanohydrolase inhibitor
4-alpha-D-glucan glucanohydrolase inhibitors
An EC 3.2.1.* (glycosidase) inhibitor that interferes with the action of alpha-amylase (EC 3.2.1.1).
A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 2.
prostaglandin-endoperoxide synthase 2 inhibitor
prostaglandin-endoperoxide synthase 2 inhibitors
A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 1.
prostaglandin-endoperoxide synthase 1 inhibitor
prostaglandin-endoperoxide synthase 1 inhibitors
EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the activity of urease (EC 3.5.1.5), reducing hydrolysis.
EC 2.5.1.1 (dimethylallyltranstransferase) inhibitor
(2E,6E)-farnesyl diphosphate synthetase inhibitor
(2E,6E)-farnesyl diphosphate synthetase inhibitors
An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of dimethylallyltranstransferase (EC 2.5.1.1).
DMAPP:IPP-dimethylallyltransferase inhibitor
DMAPP:IPP-dimethylallyltransferase inhibitors
EC 2.5.1.1 (dimethylallyltranstransferase) inhibitors
dimethylallyl-diphosphate:isopentenyl-diphosphate dimethylallyltranstransferase inhibitor
dimethylallyl-diphosphate:isopentenyl-diphosphate dimethylallyltranstransferase inhibitors
dimethylallyltranstransferase (EC 2.5.1.1) inhibitor
dimethylallyltranstransferase (EC 2.5.1.1) inhibitors
dimethylallyltranstransferase inhibitors
geranyl pyrophosphate synthase inhibitor
geranyl pyrophosphate synthase inhibitors
geranyl pyrophosphate synthetase inhibitor
geranyl pyrophosphate synthetase inhibitors
trans-farnesyl pyrophosphate synthetase inhibitor
trans-farnesyl pyrophosphate synthetase inhibitors
An agent that inhibits bone resorption and/or favor bone mineralization and bone regeneration. Used to heal bone fractures and to treat bone diseases such as osteopenia and osteoporosis.
A drug used to treat hyperthyroidism by reducing the excessive production of thyroid hormones.
EC 1.5.1.3 (dihydrofolate reductase) inhibitor
An EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of dihydrofolate reductase (EC 1.5.1.3).
EC 1.5.1.3 (dihydrofolate reductase) inhibitors
NADPH-dihydrofolate reductase inhibitors
dihydrofolate reductase (EC 1.5.1.3) inhibitor
dihydrofolate reductase (EC 1.5.1.3) inhibitors
tetrahydrofolate dehydrogenase inhibitor
tetrahydrofolate dehydrogenase inhibitors
A reagent with two reactive groups, usually at opposite ends of the molecule, that are capable of reacting with and thereby forming bridges between macromolecules, principally side chains of amino acids in proteins, allowing the locations of naturally reactive areas within the proteins to be identified.
A drug used to treat trichomonas infections.
A substance used either in the prevention or facilitation of pregnancy.
A chemical substance that interrupts pregnancy after implantation.
EC 2.4.1.129 (peptidoglycan glycosyltransferase) inhibitor
An EC 2.4.1.* (hexosyltransferase) inhibitor that interferes with the action of peptidoglycan glycosyltransferase (EC 2.4.1.129).
EC 2.4.1.129 (peptidoglycan glycosyltransferase) inhibitors
[poly-N-acetyl-D-glucosaminyl-(1->4)-(N-acetyl-D-muramoylpentapeptide)]-diphosphoundecaprenol:[N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide]-diphosphoundecaprenol disaccharidetransferase inhibitor
[poly-N-acetyl-D-glucosaminyl-(1->4)-(N-acetyl-D-muramoylpentapeptide)]-diphosphoundecaprenol:[N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide]-diphosphoundecaprenol disaccharidetransferase inhibitors
bactoprenyldiphospho-N-acetylmuramoyl-(N-acetyl-D-glucosaminyl)-pentapeptide:peptidoglycan N-acetylmuramoyl-N-acetyl-D-glucosaminyltransferase inhibitor
bactoprenyldiphospho-N-acetylmuramoyl-(N-acetyl-D-glucosaminyl)-pentapeptide:peptidoglycan N-acetylmuramoyl-N-acetyl-D-glucosaminyltransferase inhibitors
penicillin binding protein 1B inhibitors
peptidoglycan glycosyltransferase (EC 2.4.1.129) inhibitor
peptidoglycan glycosyltransferase (EC 2.4.1.129) inhibitors
peptidoglycan glycosyltransferase inhibitor
peptidoglycan glycosyltransferase inhibitors
peptidoglycan transglycosylase inhibitor
peptidoglycan transglycosylase inhibitors
undecaprenyldiphospho-(N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide):undecaprenyldiphospho-(N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide) disaccharidetransferase inhibitor
undecaprenyldiphospho-(N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide):undecaprenyldiphospho-(N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide) disaccharidetransferase inhibitors
(R-(E))-1-(((1-(3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropaneacetic acid
1-[[[(1 R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl] phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]sulfanyl]methyl]cyclopropaneacetic acid
{1-[({(1R)-1-{3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl}-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl}sulfanyl)methyl]cyclopropyl}acetic acid
A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance.
A substance that possess antiestrogenic actions but can also produce estrogenic effects as well. It acts as complete or partial agonist or as antagonist. It can be either steroidal or nonsteroidal in structure.
retinoic acid receptor alpha/beta agonist
Any retinoic acid receptor (RAR) agonist with specificity for RARalpha and RARbeta.
A compound that interacts with progesterone receptors in target tissues to bring about effects similar to those of progesterone.
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
A topoisomerase inhibitor that inhibits DNA topoisomerase (ATP-hydrolysing), EC 5.99.1.3 (also known as topoisomerase II and as DNA gyrase), which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands.
DNA topoisomerase (ATP-hydrolysing) (EC 5.99.1.3) inhibitor
DNA topoisomerase (ATP-hydrolysing) (EC 5.99.1.3) inhibitors
DNA topoisomerase (ATP-hydrolysing) inhibitor
DNA topoisomerase (ATP-hydrolysing) inhibitors
EC 5.99.1.3 (DNA topoisomerase (ATP-hydrolysing)) inhibitor
EC 5.99.1.3 (DNA topoisomerase (ATP-hydrolysing)) inhibitors
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitors
A drug which acts to reduce estrogenic activity in the body, either by reducing the amount of estrogen or by reducing the activity of whatever estrogen is present.
An agent which regulates the physiologic mechanisms that control the appetite and food intake.
EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor
3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+)) (EC 1.3.1.22) inhibitor
3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+)) (EC 1.3.1.22) inhibitors
3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+)) inhibitor
3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+)) inhibitors
3-oxo-5alpha-steroid 4-dehydrogenase inhibitor
3-oxo-5alpha-steroid 4-dehydrogenase inhibitors
3-oxo-5alpha-steroid:NADP+ Delta(4)-oxidoreductase inhibitor
3-oxo-5alpha-steroid:NADP+ Delta(4)-oxidoreductase inhibitors
3-oxosteroid Delta4-dehydrogenase inhibitor
4-ene-3-oxosteroid 5alpha-reductase inhibitor
An EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor, NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of of 3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+)), EC 1.3.1.22, the enzyme which converts testosterone (CHEBI:17347) into the more potent androgen 5alpha-dihydrotestosterone.
Delta(4)-3-ketosteroid 5alpha-oxidoreductase inhibitor
Delta(4)-3-ketosteroid 5alpha-oxidoreductase inhibitors
EC 1.3.1.22 (3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))) inhibitor
EC 1.3.1.22 (3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))) inhibitors
EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitors
cholest-4-en-3-one 5alpha-reductase inhibitor
cholestenone 5alpha-reductase inhibitors
reduced nicotinamide adenine dinucleotide phosphate:Delta(4)-3-ketosteroid 5alpha-oxidoreductase inhibitor
reduced nicotinamide adenine dinucleotide phosphate:Delta(4)-3-ketosteroid 5alpha-oxidoreductase inhibitors
testosterone 5alpha-reductase inhibitors
testosterone Delta(4)-5alpha-reductase inhibitor
testosterone Delta(4)-5alpha-reductase inhibitors
testosterone Delta(4)-hydrogenase inhibitor
testosterone Delta(4)-hydrogenase inhibitors
EC 1.1.1.210 [3beta(or 20alpha)-hydroxysteroid dehydrogenase] inhibitor
3beta (or 20alpha)-hydroxysteroid dehydrogenase inhibitor
3beta (or 20alpha)-hydroxysteroid dehydrogenase inhibitors
3beta(or 20alpha)-hydroxysteroid dehydrogenase (EC 1.1.1.210) inhibitor
3beta(or 20alpha)-hydroxysteroid dehydrogenase (EC 1.1.1.210) inhibitors
3beta(or 20alpha)-hydroxysteroid dehydrogenase inhibitor
3beta(or 20alpha)-hydroxysteroid dehydrogenase inhibitors
3beta(or 20alpha)-hydroxysteroid:NADP(+) oxidoreductase inhibitor
3beta(or 20alpha)-hydroxysteroid:NADP(+) oxidoreductase inhibitors
3beta,20alpha-hydroxysteroid oxidoreductase inhibitor
3beta,20alpha-hydroxysteroid oxidoreductase inhibitors
3beta-hydroxysteroid dehydrogenase inhibitor
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor which interferes with the action of 3beta-hydroxysteroid dehydrogenase (EC 1.1.1.210), a group of steroidogenic enzymes.
EC 1.1.1.210 (3beta(or 20alpha)-hydroxysteroid dehydrogenase) inhibitor
EC 1.1.1.210 (3beta(or 20alpha)-hydroxysteroid dehydrogenase) inhibitors
EC 1.1.1.210 [3beta(or 20alpha)-hydroxysteroid dehydrogenase] inhibitors
dehydrogenase, 3beta,20alpha-hydroxy steroid inhibitor
dehydrogenase, 3beta,20alpha-hydroxy steroid inhibitors
An EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor which interferes with the action of aromatase (EC 1.14.14.14) and so reduces production of estrogenic steroid hormones.
A drug used to treat hyperparathyroidism by reducing the excessive production of parathyroid hormones.
A compound which inhibits or antagonises the biosynthesis or actions of estrogens.
A compound which inhibits or antagonizes the biosynthesis or actions of mineralocorticoids, a class of steroid hormones characterised by their similarity to aldosterone and their influence on salt and water balance.
Biologically active substance whose activity affects or plays a role in the functioning of the immune system.
A substance that augments, stimulates, activates, potentiates, or modulates the immune response at either the cellular or humoral level. A classical agent (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contains bacterial antigens. It could also be endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Its mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy is related to its antigen-specific immunoadjuvanticity.
A cardiovascular drug that prevents atherogenesis, the accumulation of lipid-containing plaques on the innermost layers of the arteries. Compare with antiatherosclerotic agent.
A drug used to treat allergic reactions.
An agent which overcomes insulin resistance by activation of the peroxisome proliferator activated receptor gamma (PPAR-gamma).
peroxisome proliferator-activated receptor gamma agonist
peroxisome proliferator-activated receptor gamma agonists
proliferator activated receptor gamma agonist
proliferator activated receptor gamma agonists
A role played by a chemical compound to induce direct or indirect DNA damage. Such damage can potentially lead to the formation of a malignant tumour, but DNA damage does not lead inevitably to the creation of cancerous cells.
A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities.
A chemical compound, or part thereof, which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy.
A role played by a chemical compound in biological systems with adverse consequences in embryo developments, leading to birth defects, embryo death or altered development, growth retardation and functional defect.
A deaminating agent is a role played by a chemical agent which exhibits the capability of causing the loss of an amine functional group on another molecular entity (e.g. DNA or protein).
A role played by a chemical compound exhibiting itself through the ability to induce damage to the liver in animals.
A role played by any chemical compound (natural or synthetic) exhibiting itself through the ability to induce damage to the kidneys.
A poison that interferes with the functions of the nervous system.
A role played by a chemical compound exhibiting itself through the ability to induce damage to the heart and cardiomyocytes.
Any compound used for the purpose of preserving biological tissues from decay in such a way as to allow for the preparation of thin, stained sections for subsequent histological study.
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
1-phosphatidylinositol 3-kinase inhibitor
1-phosphatidylinositol 3-kinase inhibitors
ATP:1-phosphatidyl-1D-myo-inositol 3-phosphotransferase inhibitor
ATP:1-phosphatidyl-1D-myo-inositol 3-phosphotransferase inhibitors
An inhibitor of phosphatidylinositol 3-kinase, EC 2.7.1.137, a family of related enzymes capable of phosphorylating the 3 position hydroxy group of the inositol ring of a phosphatidylinositol.
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitors
phosphatidylinositol 3-kinase (EC 2.7.1.137) inhibitor
phosphatidylinositol 3-kinase (EC 2.7.1.137) inhibitors
phosphatidylinositol 3-kinase inhibitors
phosphatidylinositol-3-OH kinase inhibitor
phosphatidylinositol-3-OH kinase inhibitors
type I phosphatidylinositol kinase inhibitor
type I phosphatidylinositol kinase inhibitors
type III phosphoinositide 3-kinase inhibitor
type III phosphoinositide 3-kinase inhibitors
An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of lipid kinases.
A drug used to prevent nausea or vomiting. An antiemetic may act by a wide range of mechanisms: it might affect the medullary control centres (the vomiting centre and the chemoreceptive trigger zone) or affect the peripheral receptors.
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor
ATP-protein transphosphorylase inhibitor
ATP-protein transphosphorylase inhibitors
ATP:protein phosphotransferase (non-specific) inhibitor
ATP:protein phosphotransferase (non-specific) inhibitors
An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of non-specific serine/threonine protein kinase (EC 2.7.11.1), a kinase enzyme involved in phosphorylation of hydroxy group of serine or threonine.
BR serine/threonine-protein kinase 2 inhibitor
BR serine/threonine-protein kinase 2 inhibitors
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitors
cAMP-dependent protein kinase A inhibitor
cAMP-dependent protein kinase A inhibitors
cAMP-dependent protein kinase inhibitors
cGMP-dependent protein kinase inhibitors
calcium/phospholipid-dependent protein kinase inhibitor
calcium/phospholipid-dependent protein kinase inhibitors
casein kinase (phosphorylating) inhibitor
casein kinase (phosphorylating) inhibitors
cyclic AMP-dependent protein kinase A inhibitor
cyclic AMP-dependent protein kinase A inhibitors
cyclic AMP-dependent protein kinase inhibitor
cyclic AMP-dependent protein kinase inhibitors
cyclic monophosphate-dependent protein kinase inhibitor
cyclic monophosphate-dependent protein kinase inhibitors
cyclic nucleotide-dependent protein kinase inhibitor
cyclic nucleotide-dependent protein kinase inhibitors
non-specific serine/threonine protein kinase (EC 2.7.11.1) inhibitor
non-specific serine/threonine protein kinase (EC 2.7.11.1) inhibitors
non-specific serine/threonine protein kinase inhibitor
non-specific serine/threonine protein kinase inhibitors
phosphorylase b kinase kinase inhibitors
protein kinase (phosphorylating) inhibitor
protein kinase (phosphorylating) inhibitors
protein serine-threonine kinase inhibitor
protein serine-threonine kinase inhibitors
protein-serine/threonine kinase inhibitors
ribosomal protein S6 kinase II inhibitor
ribosomal protein S6 kinase II inhibitors
serine(threonine) protein kinase inhibitor
serine(threonine) protein kinase inhibitors
serine-specific protein kinase inhibitor
serine-specific protein kinase inhibitors
serine/threonine protein kinase inhibitor
serine/threonine protein kinase inhibitors
threonine-specific protein kinase inhibitor
threonine-specific protein kinase inhibitors
An agent that modulates the physiologic angiogenesis process. This is accomplished by endogenous angiogenic proteins and a variety of other chemicals and pharmaceutical agents.
A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent.
A dopaminergic agent that blocks the transport of dopamine into axon terminals or into storage vesicles within terminals. Most of the adrenergic uptake inhibitors also inhibit dopamine uptake.
A chemical substance which binds to specific hormone receptors activating the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites.
A drug that modulates the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites.
A drug that binds to and activates dopamine receptors.
An agent causing contraction of the pupil of the eye. Because the size of the pupil is under the antagonistic control of the sympathetic and parasympathetic systems, drugs affecting either system can cause miosis. Drugs that mimic or potentiate the parasympathetic input to the circular constrictor muscle and drugs that inhibit sympathetic input to the radial dilator muscle tend to contract the pupils.
A compound that inhibits the growth of marine organisms.
A role played by the molecular entity or part thereof within a chemical context.
A group that is introduced into a molecule by chemical modification of a functional group in order to obtain chemoselectivity in a subsequent chemical reaction.
A role played by a phosphonium ylide in a Wittig reaction.
An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
A fluorescent dye used to stain biological specimens.
A role played by an organomagnesium halide in a Grignard reaction.
A role played by a compound in a fluid state in swelling a gel, network, or solid.
A role played by a compound that facilitates the rapid drying of gels without their cracking.
A drug used to produce muscle relaxation (excepting neuromuscular blocking agents). Its primary clinical and therapeutic use is the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. Also used for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in multiple sclerosis.
A drug used for its actions on skeletal muscle.
A drug that binds to and activates gamma-aminobutyric acid receptors.
gamma-aminobutyric acid receptor agonist
gamma-aminobutyric acid receptor agonists
A substance, such as agonists, antagonists, degradation or uptake inhibitors, depleters, precursors, and modulators of receptor function, used for its pharmacological actions on GABAergic systems.
A hormone antagonist that blocks endothelin receptors.
A endothelin receptor antagonist is a drug which selectively blocks endothelin A receptors.
A compound which binds and activates the prostacyclin receptor IP1, but has only partial efficacy at the receptor relative to a full agonist.
A biological role played by the molecular entity or part thereof within a biochemical context.
A role played by the molecular entity or part thereof which causes the development of a pathological process.
A biological role which describes how a drug interacts within a biological system and how the interactions affect its medicinal properties.
Any molecule or ion capable of binding to a central metal atom to form coordination complexes.
A chemical role played by the molecular entity or part thereof in a photochemical process.
A role played by a molecular entity or part thereof in a photobiochemical process.
Any substance introduced into a living organism with therapeutic or diagnostic purpose.
An organic dye characterized by an aromatic four-membered ring system derived from squaric acid.
A chemical substance that encourages a cell to commence cell division, triggering mitosis.
An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of sterol methyltransferase.
An EC 3.2.* (glycosylase) inhibitor that interferes with the action of any glycosidase (i.e. enzymes hydrolysing O- and S-glycosyl compounds, EC 3.2.1.*).
EC 3.2.1.18 (exo-alpha-sialidase) inhibitor
An antiviral drug targeted at influenza viruses. Its mode of action consists of blocking the function of the viral neuraminidase protein (EC 3.2.1.18), thus preventing the virus from budding from the host cell.
EC 3.2.1.18 (exo-alpha-sialidase) inhibitors
N-acylneuraminate glycohydrolase inhibitor
N-acylneuraminate glycohydrolase inhibitors
exo-alpha-sialidase (EC 3.2.1.18) inhibitor
exo-alpha-sialidase (EC 3.2.1.18) inhibitors
EC 3.1.26.13 (retroviral ribonuclease H) inhibitor
An inhibitor of ribonuclease H (EC 3.1.26.13), an enzyme required for specific hydrolysis of the RNA strand of an RNA/DNA hybrid.
EC 3.1.26.13 (retroviral ribonuclease H) inhibitors
retroviral reverse transcriptase RNaseH inhibitor
retroviral reverse transcriptase RNaseH inhibitors
retroviral ribonuclease H (EC 3.1.26.13) inhibitor
retroviral ribonuclease H (EC 3.1.26.13) inhibitors
A drug that blocks the action of proteasomes, cellular complexes that break down proteins.
A group that serves to protect a phosphate group in the context of a synthesis.
A group that serves to protect a carboxylic acid function in the context of a synthesis.
The biological role played by a material entity when bound by a receptor of the adaptive immune system. Specific site on an antigen to which an antibody binds.
A compound that exhibits agonist activity at the P2Y2 receptor.
A substance used to cause adherence of tissue to tissue or tissue to non-tissue surfaces, as for prostheses.
A drug that binds to and activates gamma-hydroxybutyric acid receptors.
The role played by a molecular entity, such as an atom or free radical, which is involved in chain-propagating reactions.
A topoisomerase inhibitor that inhibits DNA topoisomerase IV, which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands.
An EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor that interferes with the action of diamine oxidase (EC 1.4.3.22).
EC 1.4.3.22 (diamine oxidase) inhibitors
diamine oxidase (EC 1.4.3.22) inhibitors
histamine:oxygen oxidoreductase (deaminating) inhibitor
histamine:oxygen oxidoreductase (deaminating) inhibitors
EC 1.1.1.205 (IMP dehydrogenase) inhibitor
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of IMP dehydrogenase (EC 1.1.1.205), so blocking de novo biosynthesis of purine nucleotides.
EC 1.1.1.205 (IMP dehydrogenase) inhibitors
IMP dehydrogenase (EC 1.1.1.205) inhibitor
IMP dehydrogenase (EC 1.1.1.205) inhibitors
inosine 5'-monophosphate dehydrogenase inhibitors
inosine monophosphate dehydrogenase inhibitor
inosine monophosphate dehydrogenase inhibitors
inosine monophosphate oxidoreductase inhibitor
inosine monophosphate oxidoreductase inhibitors
An entity which inhibits the activity of HIV-1 reverse transcriptase.
A drug that suppresses spasms. These are usually caused by smooth muscle contraction, especially in tubular organs. The effect is to prevent spasms of the stomach, intestine or urinary bladder.
A compound that exhibits agonist activity at the mu-opioid receptor.
Any drug found useful in the symptomatic treatment of diarrhoea.
A drug used for its effects on the gastrointestinal system, e.g. controlling gastric acidity, regulating gastrointestinal motility and water flow, and improving digestion.
A class of anticoagulants which act by inhibiting the action of vitamin K.
An antagonist at the neurokinin-1 receptor.
An antagonist at the substance P receptor.
A drug or agent applied to the skin to control seborrhea or seborrheic dermatitis.
EC 6.3.2.* (acid--D-amino-acid ligase) inhibitor
Any inhibitor of an acid--D-amino-acid ligase (EC 6.3.2.*).
EC 6.3.2.* (acid--D-amino-acid ligase (peptide synthase)) inhibitor
EC 6.3.2.* (acid--D-amino-acid ligase (peptide synthase)) inhibitors
EC 6.3.2.* (acid--D-amino-acid ligase) inhibitors
EC 6.3.2.* (acid--amino-acid ligase) inhibitor
EC 6.3.2.* (acid--amino-acid ligase) inhibitors
EC 6.3.2.* [acid--D-amino-acid ligase (peptide synthase)] inhibitor
EC 6.3.2.* [acid--D-amino-acid ligase (peptide synthase)] inhibitors
EC 3.4.24.* (metalloendopeptidase) inhibitor
Any EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes with the activity of a metalloendopeptidase (EC 3.4.24.*).
EC 3.4.24.* (metalloendopeptidase) inhibitors
inhibitor of metalloendopeptidases (EC 3.4.24.*)
inhibitors of metalloendopeptidases (EC 3.4.24.*)
metalloendopeptidase (EC 3.4.24.*) inhibitor
metalloendopeptidase (EC 3.4.24.*) inhibitors
Any substance that stimulates an immune response in the body, such as through antibody production or by presentation to a T-cell receptor after binding to a major histocompability complex (MHC).
A substance used as an indicator of a biological state.
Any substance capable of eliciting an immune response only when attached to a large carrier such as a protein. Examples include dinitrophenols; oligosaccharides; peptides; and heavy metals.
A chemical substance which inhibits the function of gonadotrophin-releasing hormone (GnRH).
gonadotrophin-releasing hormone antagonist
gonadotrophin-releasing hormone antagonists
EC 3.4.21.* (serine endopeptidase) inhibitor
Any EC 3.4.* (hydrolases acting on peptide bond) inhibitor that inhibits the activity of a serine endopeptidase (EC 3.4.21.*).
EC 3.4.21.* (serine endopeptidase) inhibitors
inhibitor of serine endopeptidase (EC 3.4.21.*)
inhibitor of serine endopeptidase (EC 3.4.21.*)s
A compound that exhibits agonist activity at the kappa-opioid receptor.
Any compound that exhibits antagonist activity at the delta-opioid receptor.
EC 1.14.13.132 (squalene monooxygenase) inhibitor
An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of squalene monooxygenase (EC 1.14.13.132).
EC 1.14.13.132 (squalene monooxygenase) inhibitors
squalene monooxygenase (EC 1.14.13.132) inhibitor
squalene monooxygenase (EC 1.14.13.132) inhibitors
EC 4.1.1.28 (aromatic-L-amino-acid decarboxylase) inhibitor
5-hydroxytryptophan decarboxylase inhibitor
5-hydroxytryptophan decarboxylase inhibitors
An EC 4.1.1.* (carboxy-lyase) inhibitor that interferes with the action of aromatic-L-amino-acid decarboxylase (EC 4.1.1.28).
EC 4.1.1.28 (aromatic-L-amino-acid decarboxylase) inhibitors
aromatic amino acid decarboxylase inhibitor
aromatic amino acid decarboxylase inhibitors
aromatic-L-amino-acid decarboxylase (EC 4.1.1.28) inhibitor
aromatic-L-amino-acid decarboxylase (EC 4.1.1.28) inhibitors
aromatic-L-amino-acid decarboxylase inhibitor
aromatic-L-amino-acid decarboxylase inhibitors
hydroxytryptophan decarboxylase inhibitor
hydroxytryptophan decarboxylase inhibitors
Any EC 3.4.* (hydrolases acting on peptide bond) inhibitor that inhibits the action of a dipeptidase (EC 3.4.13.*).
Any substance that inhibits the synthesis of DNA.
Any antigen that is a phosphorylated microbial metabolite which activates an immune response in humans.
EC 2.3.1.50 (serine C-palmitoyltransferase) inhibitor
An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of serine palmitoyltransferase (EC 2.3.1.50).
EC 2.3.1.50 (serine C-palmitoyltransferase) inhibitors
acyl-CoA:serine C-2 acyltransferase (decarboxylating) inhibitor
acyl-CoA:serine C-2 acyltransferase (decarboxylating) inhibitors
palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) inhibitor
palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) inhibitors
serine C-palmitoyltransferase (EC 2.3.1.50) inhibitor
serine C-palmitoyltransferase (EC 2.3.1.50) inhibitors
serine C-palmitoyltransferase inhibitors
A EC 2.4.1.* (hexosyltransferase) inhibitor that inhibits the action of chitin synthase (EC 2.4.1.16).
EC 2.4.1.16 (chitin synthase) inhibitors
UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyl-transferase inhibitor
UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyl-transferase inhibitors
chitin synthase (EC 2.4.1.16) inhibitors
chitin-UDP N-acetylglucosaminyltransferase inhibitor
chitin-UDP N-acetylglucosaminyltransferase inhibitors
chitin-UDP acetyl-glucosaminyl transferase inhibitor
chitin-UDP acetyl-glucosaminyl transferase inhibitors
chitin-uridine diphosphate acetylglucosaminyltransferase inhibitor
chitin-uridine diphosphate acetylglucosaminyltransferase inhibitors
trans-N-acetylglucosaminosylase inhibitor
trans-N-acetylglucosaminosylase inhibitors
Any drug which blocks vasopressin receptors.
arginine vasopressin receptor antagonist
arginine vasopressin receptor antagonists
A drug, usually applied topically, that relieves pruritus (itching).
Any drug which binds to vasopressin receptors and triggers a response.
A reagent that forms a bond to its reaction partner (the nucleophile) by accepting both bonding electrons from that reaction partner.
A reagent that forms a bond to its reaction partner (the electrophile) by donating both bonding electrons.
A reagent used to improve selectivity in chromatographic analyses or separations, e.g. by formation of a derivative or by modification of the mobile phase.
A surfactant molecule with hydrophilic groups at both ends of a hydrophobic hydrocarbon chain
A drug used for the treatment of hyperplasia (increaced cell production within an organ or tissue).
Any drug used to depigment skin, normally by decreasing the excretion of melanin from melanocytes.
A drug which interferes with the binding, fusion and entry of an HIV virion to a human cell. By blocking this step in HIV's replication cycle, such agents slow the progression from HIV infection to AIDS.
EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor
A DNA polymerase inhibitor that interferes with the activity of reverse transcriptase, EC 2.7.7.49, a viral DNA polymerase enzyme that retroviruses need in order to reproduce.
DNA nucleotidyltransferase (RNA-directed) inhibitor
DNA nucleotidyltransferase (RNA-directed) inhibitors
EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitors
RNA-dependent deoxyribonucleate nucleotidyltransferase inhibitor
RNA-dependent deoxyribonucleate nucleotidyltransferase inhibitors
RNA-directed DNA polymerase (EC 2.7.7.49) inhibitor
RNA-directed DNA polymerase (EC 2.7.7.49) inhibitors
RNA-instructed DNA polymerase inhibitors
deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (RNA-directed) inhibitor
deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (RNA-directed) inhibitors
A surfactant molecule possessing both hydrophilic and lipophilic properties.
Any EC 1.14.18.* (oxidoreductase acting on paired donors, miscellaneous compound as one donor, incorporating 1 atom of oxygen) inhibitor that interferes with the action of tyrosinase (monophenol monooxygenase), EC 1.14.18.1, an enzyme that catalyses the oxidation of phenols (such as tyrosine) and is widespread in plants and animals.
L-tyrosine,L-dopa:oxygen oxidoreductase inhibitor
L-tyrosine,L-dopa:oxygen oxidoreductase inhibitors
NN-acetyl-6-hydroxytryptophan oxidase inhibitor
NN-acetyl-6-hydroxytryptophan oxidase inhibitors
monophenol dihydroxyphenylalanine:oxygen oxidoreductase inhibitor
monophenol dihydroxyphenylalanine:oxygen oxidoreductase inhibitors
monophenol, dihydroxy-L-phenylalanine oxygen oxidoreductase inhibitor
monophenol, dihydroxy-L-phenylalanine oxygen oxidoreductase inhibitors
EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor
ATP phosphohydrolase (Ca(2+)-transporting) inhibitor
ATP phosphohydrolase (Ca(2+)-transporting) inhibitors
An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of Ca(2+)-transporting ATPase (EC 3.6.3.8).
Ca(2+)-transporting ATPase (EC 3.6.3.8) inhibitor
Ca(2+)-transporting ATPase (EC 3.6.3.8) inhibitors
EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitors
sarco(endo)plasmic reticulum Ca(2+)-ATPase inhibitor
sarco(endo)plasmic reticulum Ca(2+)-ATPase inhibitors
sarcoplasmic reticulum ATPase inhibitors
Any macromolecule whose structure mimics that of an epitope. When applied to immunisation, a mimotope induces the desired antibody specificities exclusively based on the principle of molecular mimicry.
EC 3.4.* (hydrolases acting on peptide bond) inhibitor
A hydrolase inhibitor that interferes with the action of any hydrolase acting on peptide bonds (peptidase), EC 3.4.*.*).
EC 3.4.* (hydrolase acting on peptide bond) inhibitor
EC 3.4.* (hydrolase acting on peptide bonds) inhibitors
EC 3.4.* (hydrolases acting on peptide bond) inhibitors
inhibitor of hydrolases acting on peptide bond (EC 3.4.*)
inhibitors of hydrolases acting on peptide bond (EC 3.4.*)
Any EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the activity of a glutaminase (EC 3.5.1.2) and thus the generation of glutamate from glutamine.
Any hormone produced by the thyroid gland
Any member of the class of herbicides whose members contain a phenoxy or substituted phenoxy group.
Any agent that acts on an opioid receptor or affects the life cycle of an opioid transmitter.
Any agent that acts on a mu-opioid receptor.
Any agent that acts on a delta-opioid receptor.
Any agent that acts on a kappa-opioid receptor.
An agent that binds to but does not activate an opioid receptor thereby blocking the actions of endogenous or exogenous opioid receptor agonists.
An agent that selectively binds to and activates an opioid receptor.
Any substance that inhibits the action of N-methyl-D-aspartate (NMDA) receptors. They tend to induce a state known as dissociative anesthesia, marked by catalepsy, amnesia, and analgesia, while side effects can include hallucinations, nightmares, and confusion. Due to their psychotomimetic effects, many NMDA receptor antagonists are used as recreational drugs.
N-methyl-D-aspartate receptor antagonist
N-methyl-D-aspartate receptor antagonists
A chiral compound used to induce stereoselectivity into a reaction.
An agent which blocks glucagon receptors.
EC 4.2.1.20 (tryptophan synthase) inhibitor
An EC 4.2.1.* (hydro-lyases) inhibitor that interferes with the action of tryptophan synthase (EC 4.2.1.20).
EC 4.2.1.20 (tryptophan synthase) inhibitors
L-serine hydro-lyase (adding indoleglycerol-phosphate) inhibitor
L-serine hydro-lyase (adding indoleglycerol-phosphate) inhibitors
indoleglycerol phosphate aldolase inhibitor
indoleglycerol phosphate aldolase inhibitors
tryptophan synthase (EC 4.2.1.20) inhibitor
tryptophan synthase (EC 4.2.1.20) inhibitors
An enzyme inhibitor, generally irreversible, that is similar in structure to a particular substrate for a specific enzyme.
Any substance which inhibits the action of receptors for excitatory amino acids.
excitatory amino acid receptor antagonist
excitatory amino acid receptor antagonists
Any substance that possesses little anaesthetic effect by itself, but which enhances or potentiates the anaesthetic action of other drugs when given at the same time.
Any pharmacological or immunological agent that modifies the effect of other agents such as drugs or vaccines while having few if any direct effects when given by itself.
An antigen capable, on its own, of inducing an immune response.
Any substance that interacts with tubulin to inhibit or promote polymerisation of microtubules.
EC 2.5.1.9 (riboflavin synthase) inhibitor
6,7-dimethyl-8-(1-D-ribityl)lumazine:6,7-dimethyl-8-(1-D-ribityl)lumazine 2,3-butanediyltransferase inhibitor
6,7-dimethyl-8-(1-D-ribityl)lumazine:6,7-dimethyl-8-(1-D-ribityl)lumazine 2,3-butanediyltransferase inhibitors
An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that inhibits the action of riboflavin synthase (EC 2.5.1.9).
EC 2.5.1.9 (riboflavin synthase) inhibitors
riboflavin synthase (EC 2.5.1.9) inhibitor
riboflavin synthase (EC 2.5.1.9) inhibitors
A toxin that is produced by a biological organism such as a microbe, animal or plant which interferes with the function of the kidney in animals.
A hormone antagonist that blocks angiotensin receptors.
A drug used in the treatment of bile or liver disorders.
EC 3.5.1.98 (histone deacetylase) inhibitor
An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the function of histone deacetylase (EC 3.5.1.98).
EC 3.5.1.98 (histone deacetylase) inhibitors
histone deacetylase (EC 3.5.1.98) inhibitor
histone deacetylase (EC 3.5.1.98) inhibitors
inositol phosphorylceramide synthase inhibitor
An enzyme inhibitor that inhibits the action of inositol phosphorylceramide synthase.
EC 1.14.13.39 (nitric oxide synthase) inhibitor
An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of nitric oxide synthase (EC 1.14.13.39).
EC 1.14.13.39 (nitric oxide synthase) inhibitors
endothelium-derived relaxation factor-forming enzyme inhibitor
endothelium-derived relaxation factor-forming enzyme inhibitors
endothelium-derived relaxing factor synthase inhibitor
endothelium-derived relaxing factor synthase inhibitors
nitric oxide synthase (EC 1.14.13.39) inhibitor
nitric oxide synthase (EC 1.14.13.39) inhibitors
Any substance that interacts with tubulin to promote polymerisation of microtubules.
Any substance that interacts with tubulin to inhibit polymerisation of microtubules.
An agonist that selectively binds to and activates a metabotropic glutamate receptor.
metabotropic glutamate receptor agonists
Any donor that can transfer acyl groups between molecular entities.
EC 1.4.7.1 [glutamate synthase (ferredoxin)] inhibitor
An EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor that interferes with the action of any glutamate synthase.
EC 1.4.7.1 [glutamate synthase (ferredoxin)] inhibitors
L-glutamate:ferredoxin oxidoreductase (transaminating) inhibitor
L-glutamate:ferredoxin oxidoreductase (transaminating) inhibitors
ferredoxin-dependent glutamate synthase inhibitor
ferredoxin-dependent glutamate synthase inhibitors
ferredoxin-glutamate synthase inhibitors
glutamate synthase (ferredoxin) (EC 1.4.7.1) inhibitor
glutamate synthase (ferredoxin) (EC 1.4.7.1) inhibitors
glutamate synthase (ferredoxin) inhibitor
glutamate synthase (ferredoxin) inhibitors
glutamate synthase (ferredoxin-dependent) inhibitor
glutamate synthase (ferredoxin-dependent) inhibitors
A class of secondary metabolites developed by many plants to influence the behaviour, growth or survival of herbivores, and thus acting as a defence against herbivory.
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
ATP:[protein]-L-tyrosine O-phosphotransferase (receptor-type) inhibitor
ATP:[protein]-L-tyrosine O-phosphotransferase (receptor-type) inhibitors
An EC 2.7.10.* (protein-tyrosine kinase) inhibitor that interferes with the action of receptor protein-tyrosine kinase (EC 2.7.10.1).
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitors
ephrin-B3 receptor tyrosine kinase inhibitor
insulin receptor protein-tyrosine kinase inhibitor
neurite outgrowth regulating kinase inhibitor
novel oncogene with kinase-domain inhibitor
receptor protein tyrosine kinase inhibitor
receptor protein-tyrosine kinase (EC 2.7.10.1) inhibitor
receptor protein-tyrosine kinase (EC 2.7.10.1) inhibitors
receptor protein-tyrosine kinase inhibitor
receptor protein-tyrosine kinase inhibitors
A molecular messenger in which the molecule is specifically involved in transmitting information between cells. Such molecules are released from the cell sending the signal, cross over the gap between cells by diffusion, and interact with specific receptors in another cell, triggering a response in that cell by activating a series of enzyme controlled reactions which lead to changes inside the cell.
EC 2.3.1.24 (sphingosine N-acyltransferase) inhibitor
An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of sphingosine N-acyltransferase (EC 2.3.1.24).
EC 2.3.1.24 (sphingosine N-acyltransferase) inhibitors
acyl-CoA:sphingosine N-acyltransferase inhibitor
acyl-CoA:sphingosine N-acyltransferase inhibitors
sphingosine N-acyltransferase (EC 2.3.1.24) inhibitor
sphingosine N-acyltransferase (EC 2.3.1.24) inhibitors
sphingosine N-acyltransferase inhibitors
EC 4.2.1.3 (aconitate hydratase) inhibitor
An EC 4.2.1.* (hydro-lyases) inhibitor that interferes with the function of aconitase (EC 4.2.1.3).
EC 4.2.1.3 (aconitate hydratase) inhibitors
aconitate hydratase (EC 4.2.1.3) inhibitor
aconitate hydratase (EC 4.2.1.3) inhibitors
citrate(isocitrate) hydro-lyase (cis-aconitate-forming) inhibitor
citrate(isocitrate) hydro-lyase (cis-aconitate-forming) inhibitors
citrate(isocitrate) hydro-lyase inhibitor
citrate(isocitrate) hydro-lyase inhibitors
EC 3.11.1.3 (phosphonopyruvate hydrolase) inhibitor
An EC 3.11.1.* (hydrolases acting on C-P bonds of phosphono-acetaldehyde, -acetate, or -pyruvate) inhibitor that interferes with the action of phosphonopyruvate hydrolase (EC 3.11.1.3).
EC 3.11.1.3 (phosphonopyruvate hydrolase) inhibitors
phosphonopyruvate hydrolase (EC 3.11.1.3) inhibitor
phosphonopyruvate hydrolase (EC 3.11.1.3) inhibitors
An antagonist that blocks glycine receptors.
Any additive that enhances the efficiency of fuel.
Any compound that is able to prevent damage to the liver.
EC 4.3.1.24 (phenylalanine ammonia-lyase) inhibitor
An EC 4.3.* (C-N lyase) inhibitor that interferes with the action of phenylalanine ammonia-lyase (EC 4.3.1.24).
EC 4.3.1.24 (phenylalanine ammonia-lyase) inhibitors
L-phenylalanine ammonia-lyase (trans-cinnamate-forming) inhibitor
L-phenylalanine ammonia-lyase (trans-cinnamate-forming) inhibitors
L-phenylalanine ammonia-lyase inhibitors
phenylalanine ammonia-lyase (EC 4.3.1.24) inhibitor
phenylalanine ammonia-lyase (EC 4.3.1.24) inhibitors
An EC 1.2.3.* (oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor) inhibitor which interferes with the action of aldehyde oxidase (EC 1.2.3.1).
EC 1.2.3.1 (aldehyde oxidase) inhibitors
aldehyde oxidase (EC 1.2.3.1) inhibitors
aldehyde:oxygen oxidoreductase inhibitor
aldehyde:oxygen oxidoreductase inhibitors
An agonist that selectively binds to and activates an odorant receptor.
Any compound that inhibits the action of tankyrase.
EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor
ADP-ribosyltransferase (polymerising) inhibitor
ADP-ribosyltransferase (polymerising) inhibitors
ADP-ribosyltransferase (polymerizing) inhibitor
ADP-ribosyltransferase (polymerizing) inhibitors
An EC 2.4.2.* (pentosyltransferase) inhibitor that interferes with the action of a NAD(+) ADP-ribosyltransferase (EC 2.4.2.30).
EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitors
NAD(+) ADP-ribosyltransferase (EC 2.4.2.30) inhibitor
NAD(+) ADP-ribosyltransferase (EC 2.4.2.30) inhibitors
NAD(+) ADP-ribosyltransferase inhibitors
NAD(+):poly(ADP-D-ribosyl)-acceptor ADP-D-ribosyl-transferase inhibitor
NAD(+):poly(ADP-D-ribosyl)-acceptor ADP-D-ribosyl-transferase inhibitors
NAD(+):poly(adenosine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase inhibitor
NAD(+):poly(adenosine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase inhibitors
poly(adenosine diphosphate ribose) polymerase inhibitor
poly(adenosine diphosphate ribose) polymerase inhibitors
An EC 2.4.99.* (glycosyltransferases transferring other glycosyl groups) inhibitor that interferes with the action of a sialyltransferase.
The chemical role played by a substance that stabilizes an emulsion by increasing its kinetic stability.
A food additive used to form or maintain a uniform emulsion of two (or more) phases in a food.
Any compound that induces or regulates osteogenesis.
A catalyst that facilitates the migration of a reactant from one phase into another phase where reaction occurs.
Chemical role played by a material when used to promote crystallisation.
EC 2.4.2.1 (purine-nucleoside phosphorylase) inhibitor
An EC 2.4.2.* (pentosyltransferase) inhibitor that interferes with the action of purine nucleoside phosphorylase (EC 2.4.2.1).
EC 2.4.2.1 (purine-nucleoside phosphorylase) inhibitors
inosine-guanosine phosphorylase inhibitor
inosine-guanosine phosphorylase inhibitors
purine deoxynucleoside phosphorylase inhibitor
purine deoxynucleoside phosphorylase inhibitors
purine deoxyribonucleoside phosphorylase inhibitor
purine deoxyribonucleoside phosphorylase inhibitors
purine nucleoside phosphorylase inhibitor
purine nucleoside phosphorylase inhibitors
purine ribonucleoside phosphorylase inhibitor
purine ribonucleoside phosphorylase inhibitors
purine-nucleoside phosphorylase (EC 2.4.2.1) inhibitor
purine-nucleoside phosphorylase (EC 2.4.2.1) inhibitors
purine-nucleoside phosphorylase inhibitor
purine-nucleoside phosphorylase inhibitors
purine-nucleoside:phosphate ribosyltransferase inhibitor
purine-nucleoside:phosphate ribosyltransferase inhibitors
sphingosine-1-phosphate receptor agonist
An agonist that binds to and activates sphingosine 1-phosphate receptors.
sphingosine 1-phosphate receptor agonist
sphingosine 1-phosphate receptor agonists
sphingosine-1-phosphate receptor agonists
Any substance that inhibits the release of insulin
An EC 1.1.3.* (oxidoreductase acting on donor CH-OH group, oxygen as acceptor) inhibitor that interferes with the action of alcohol oxidase (EC 1.1.3.13).
EC 1.1.3.13 (alcohol oxidase) inhibitors
alcohol oxidase (EC 1.1.3.13) inhibitors
alcohol:oxygen oxidoreductase inhibitors
EC 4.2.1.22 (cystathionine beta-synthase) inhibitor
An EC 4.2.1.* (hydro-lyases) inhibitor that interferes with the action of cystathionine beta-synthase (EC 4.2.1.22).
EC 4.2.1.22 (cystathionine beta-synthase) inhibitors
L-serine hydro-lyase (adding homocysteine) inhibitor
L-serine hydro-lyase (adding homocysteine) inhibitors
L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming) inhibitor
L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming) inhibitors
cystathionine beta-synthase (EC 4.2.1.22) inhibitor
cystathionine beta-synthase (EC 4.2.1.22) inhibitors
EC 2.3.1.21 (carnitine O-palmitoyltransferase) inhibitor
An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of mitochondrial carnitine O-palmitoyltransferase (EC 2.3.1.21).
CPT I (outer membrane carnitine palmitoyl transferase) inhibitor
CPT I (outer membrane carnitine palmitoyl transferase) inhibitors
EC 2.3.1.21 (carnitine O-palmitoyltransferase) inhibitors
L-carnitine palmitoyltransferase inhibitor
L-carnitine palmitoyltransferase inhibitors
carnitine O-palmitoyltransferase (EC 2.3.1.21) inhibitor
carnitine O-palmitoyltransferase (EC 2.3.1.21) inhibitors
carnitine O-palmitoyltransferase inhibitor
carnitine O-palmitoyltransferase inhibitors
carnitine palmitoyltransferase II inhibitor
carnitine palmitoyltransferase II inhibitors
carnitine palmitoyltransferase inhibitor
carnitine palmitoyltransferase inhibitors
carnitine palmitoyltransferase-1 inhibitor
carnitine palmitoyltransferase-1 inhibitors
carnitine palmitoyltransferase-A inhibitor
carnitine palmitoyltransferase-A inhibitors
mitochondrial carnitine palmitoyltransferase-1 inhibitor
mitochondrial carnitine palmitoyltransferase-1 inhibitors
outer malonyl-CoA inhibitable carnitine palmitoyltransferase inhibitor
outer malonyl-CoA inhibitable carnitine palmitoyltransferase inhibitors
palmitoyl-CoA:L-carnitine O-palmitoyltransferase inhibitor
palmitoyl-CoA:L-carnitine O-palmitoyltransferase inhibitors
palmitoylcarnitine transferase inhibitor
palmitoylcarnitine transferase inhibitors
An inhibitor that interferes with the process of T-cell proliferation.
A small protein-like chain designed to mimic a peptide.
The element or compound in a reduction-oxidation (redox) reaction that donates an electron to another species.
A substance that removes electrons from another reactant in a redox reaction.
sodium-dependent Pi-transporter inhibitor
Any substance that inhibits the action of sodium-dependent Pi-transporters.
sodium-dependent inorganic phosphate cotransporter inhibitor
sodium-dependent inorganic phosphate transporter inhibitor
EC 3.1.3.1 (alkaline phosphatase) inhibitor
An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of alkaline phosphatase (EC 3.1.3.1).
EC 3.1.3.1 (alkaline phosphatase) inhibitors
alkaline phosphatase (EC 3.1.3.1) inhibitor
alkaline phosphatase (EC 3.1.3.1) inhibitors
orthophosphoric-monoester phosphohydrolase (alkaline optimum) inhibitor
orthophosphoric-monoester phosphohydrolase (alkaline optimum) inhibitors
phosphate-monoester phosphohydrolase (alkaline optimum) inhibitor
phosphate-monoester phosphohydrolase (alkaline optimum) inhibitors
fibroblast growth factor receptor antagonist
An antagonist at the fibroblast growth factor receptor.
fibroblast growth factor receptor antagonists
fibroblast growth factor receptor inhibitor
fibroblast growth factor receptor inhibitors
A substance capable of undergoing rapid and highly exothermic decomposition.
EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor
An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of Na(+)/K(+)-transporting ATPase (EC 3.6.3.9).
EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitors
Na(+)/K(+)-transporting ATPase (EC 3.6.3.9) inhibitor
Na(+)/K(+)-transporting ATPase (EC 3.6.3.9) inhibitors
Na(+)/K(+)-transporting ATPase inhibitor
Na(+)/K(+)-transporting ATPase inhibitors
sodium-potassium adenosine triphosphatase inhibitor
sodium-potassium adenosine triphosphatase inhibitors
Any drug which binds to gonadotropin-releasing hormone receptors and triggers a response.
gonadotrophin releasing hormone agonists
An agonist that selectively binds to and activates a glucocorticoid receptor.
An antogonist that blocks chemokine receptor 5 (CCR5).
EC 2.6.1.19 (4-aminobutyrate--2-oxoglutarate transaminase) inhibitor
4-aminobutanoate:2-oxoglutarate aminotransferase inhibitor
4-aminobutanoate:2-oxoglutarate aminotransferase inhibitors
4-aminobutyrate aminotransferase inhibitor
4-aminobutyrate aminotransferase inhibitors
4-aminobutyrate--2-ketoglutarate aminotransferase inhibitor
4-aminobutyrate--2-ketoglutarate aminotransferase inhibitors
4-aminobutyrate--2-oxoglutarate aminotransferase inhibitor
4-aminobutyrate--2-oxoglutarate aminotransferase inhibitors
4-aminobutyrate--2-oxoglutarate transaminase (EC 2.6.1.19) inhibitor
4-aminobutyrate--2-oxoglutarate transaminase (EC 2.6.1.19) inhibitors
4-aminobutyrate--2-oxoglutarate transaminase inhibitor
4-aminobutyrate--2-oxoglutarate transaminase inhibitors
4-aminobutyrate-2-oxoglutarate transaminase inhibitor
4-aminobutyrate-2-oxoglutarate transaminase inhibitors
4-aminobutyric acid 2-ketoglutaric acid aminotransferase inhibitor
4-aminobutyric acid 2-ketoglutaric acid aminotransferase inhibitors
4-aminobutyric acid aminotransferase inhibitor
4-aminobutyric acid aminotransferase inhibitors
An EC 2.6.1.* (transaminase) inhibitor that interferes with the action of 4-aminobutyrate--2-oxoglutarate transaminase (EC 2.6.1.19).
EC 2.6.1.19 (4-aminobutyrate--2-oxoglutarate transaminase) inhibitors
GABA--2-oxoglutarate aminotransferase inhibitor
GABA--2-oxoglutarate aminotransferase inhibitors
GABA--2-oxoglutarate transaminase inhibitor
GABA--2-oxoglutarate transaminase inhibitors
GABA--alpha-ketoglutarate aminotransferase inhibitors
GABA--alpha-ketoglutarate transaminase inhibitor
GABA--alpha-ketoglutarate transaminase inhibitors
GABA--alpha-ketoglutaric acid transaminase inhibitor
GABA--alpha-ketoglutaric acid transaminase inhibitors
GABA--alpha-oxoglutarate aminotransferase inhibitor
GABA--alpha-oxoglutarate aminotransferase inhibitors
GABA--oxoglutarate aminotransferase inhibitor
GABA--oxoglutarate aminotransferase inhibitors
GABA--oxoglutarate transaminase inhibitor
GABA--oxoglutarate transaminase inhibitors
aminobutyrate aminotransferase inhibitor
aminobutyrate aminotransferase inhibitors
beta-alanine aminotransferase inhibitors
beta-alanine--oxoglutarate aminotransferase inhibitor
beta-alanine--oxoglutarate aminotransferase inhibitors
beta-alanine--oxoglutarate transaminase inhibitor
beta-alanine--oxoglutarate transaminase inhibitors
gamma-amino-N-butyrate transaminase inhibitor
gamma-amino-N-butyrate transaminase inhibitors
gamma-aminobutyrate aminotransaminase inhibitor
gamma-aminobutyrate aminotransaminase inhibitors
gamma-aminobutyrate transaminase inhibitor
gamma-aminobutyrate transaminase inhibitors
gamma-aminobutyrate--alpha-ketoglutarate aminotransferase inhibitor
gamma-aminobutyrate--alpha-ketoglutarate aminotransferase inhibitors
gamma-aminobutyrate--alpha-ketoglutarate transaminase inhibitor
gamma-aminobutyrate--alpha-ketoglutarate transaminase inhibitors
gamma-aminobutyrate:alpha-oxoglutarate aminotransferase inhibitor
gamma-aminobutyrate:alpha-oxoglutarate aminotransferase inhibitors
gamma-aminobutyric acid aminotransferase inhibitor
gamma-aminobutyric acid aminotransferase inhibitors
gamma-aminobutyric acid pyruvate transaminase inhibitor
gamma-aminobutyric acid pyruvate transaminase inhibitors
gamma-aminobutyric acid transaminase inhibitor
gamma-aminobutyric acid transaminase inhibitors
gamma-aminobutyric acid--2-oxoglutarate transaminase inhibitor
gamma-aminobutyric acid--2-oxoglutarate transaminase inhibitors
gamma-aminobutyric acid--alpha-ketoglutarate transaminase inhibitor
gamma-aminobutyric acid--alpha-ketoglutarate transaminase inhibitors
gamma-aminobutyric acid--alpha-ketoglutaric acid aminotransferase inhibitor
gamma-aminobutyric acid--alpha-ketoglutaric acid aminotransferase inhibitors
gamma-aminobutyric transaminase inhibitor
gamma-aminobutyric transaminase inhibitors
glutamate--succinic semialdehyde transaminase inhibitor
glutamate--succinic semialdehyde transaminase inhibitors
EC 2.1.1.45 (thymidylate synthase) inhibitor
5,10-methylenetetrahydrofolate:dUMP C-methyltransferase inhibitor
5,10-methylenetetrahydrofolate:dUMP C-methyltransferase inhibitors
An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of thymidylate synthase (EC 2.1.1.45).
EC 2.1.1.45 (thymidylate synthase) inhibitors
methylenetetrahydrofolate:dUMP C-methyltransferase inhibitor
methylenetetrahydrofolate:dUMP C-methyltransferase inhibitors
EC 2.1.2.2 (phosphoribosylglycinamide formyltransferase) inhibitor
10-formyltetrahydrofolate:5'-phosphoribosylglycinamide N-formyltransferase inhibitors
2-amino-N-ribosylacetamide 5'-phosphate transformylase inhibitor
5,10-methenyltetrahydrofolate:2-amino-N-ribosylacetamide ribonucleotide transformylase inhibitor
5,10-methenyltetrahydrofolate:2-amino-N-ribosylacetamide ribonucleotide transformylase inhibitors
An EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor that interferes with the action of phosphoribosylglycinamide formyltransferase (EC 2.1.2.2).
EC 2.1.2.2 (phosphoribosylglycinamide formyltransferase) inhibitors
glycinamide ribonucleotide formyltransferase inhibitor
glycinamide ribonucleotide formyltransferase inhibitors
glycinamide ribonucleotide transformylase inhibitor
glycinamide ribonucleotide transformylase inhibitors
phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) inhibitor
phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) inhibitors
phosphoribosylglycinamide formyltransferase inhibitor
phosphoribosylglycinamide formyltransferase inhibitors
Any compound that can be used for the treatment of neurodegenerative disorders.
An agonist that selectively binds to and activates a retinoid X receptor.
Any compound that leaves a pliable, cohesive, and continuous covering over a surface when applied to it.
A sclerotherapy agent is used to treat blood vessels or blood vessel malformations (vascular malformations) and also those of the lymphatic system by injection into the vessels, which makes them shrink.
EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitor
An EC 1.14.16.* (oxidoreductase acting on paired donors, reduced pteridine as one donor, incorporating 1 atom of oxygen) inhibitor that interferes with the action of tyrosine 3-monooxygenase (EC 1.14.16.2).
EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitors
L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating) inhibitor
L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating) inhibitors
tyrosine 3-monooxygenase (EC 1.14.16.2) inhibitor
tyrosine 3-monooxygenase (EC 1.14.16.2) inhibitors
An antagonist at the alpha1B-adrenoceptor.
An pathway inhibitor that inhibits the synthesis of cellulose.
An EC 3.6.4.10 (non-chaperonin molecular chaperone ATPase) inhibitor that blocks the action of heat shock protein 90.
metabotropic glutamate receptor antagonist
An antagonist at the metabotropic glutamate receptor.
metabotropic glutamate receptor antagonists
An agonist that selectively binds to and activates a protein kinase C receptor
EC 3.5.1.99 (fatty acid amide hydrolase) inhibitor
An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of fatty acid amide hydrolase (EC 3.5.1.99).
EC 3.5.1.99 (fatty acid amide hydrolase) inhibitors
arachidonoylethanolamide amidohydrolase inhibitor
arachidonoylethanolamide amidohydrolase inhibitors
fatty acid amide hydrolase (EC 3.5.1.99) inhibitor
fatty acid amide hydrolase (EC 3.5.1.99) inhibitors
fatty acylamide amidohydrolase inhibitor
fatty acylamide amidohydrolase inhibitors
Any substance which is added to food to preserve or enhance its flavour and/or appearance.
A food additive that is used to change or otherwise control the acidity or alkalinity of foods. They may be acids, bases, neutralising agents or buffering agents.
A compound that exhibits agonist activity at the delta-opioid receptor.
Any compound that mimics the action of incretins, gastrointestinal hormones that cause an increase in the amount of insulin released from the beta cells of the islets of Langerhans after eating, even before blood glucose levels become elevated.
An agonist that selectively binds to and activates AMPA receptors.
alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor agonist
An agonist that selectively binds to and activates a protein kinase G receptor.
An agonist that selectively binds to and activates a protein kinase receptor.
EC 2.5.1.58 (protein farnesyltransferase) inhibitor
An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of protein farnesyltransferase (EC 2.5.1.58), one of the three enzymes in the prenyltransferase group.
EC 2.5.1.58 (protein farnesyltransferase) inhibitors
farnesyl-diphosphate:protein-cysteine farnesyltransferase inhibitor
farnesyl-diphosphate:protein-cysteine farnesyltransferase inhibitors
protein farnesyltransferase (EC 2.5.1.58) inhibitor
protein farnesyltransferase (EC 2.5.1.58) inhibitors
Any protease inhibitor that restricts the action of a cysteine protease.
A histamine agonist that binds to and activates histamine H3-receptors.
A histamine agonist that binds to and activates H4-receptors.
A histamine antagonist that selectively binds to but does not activate histamine H3 receptors, thereby blocking the actions of endogenous histamine.
EC 2.7.8.15 (UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase) inhibitor
An EC 2.7.8.* (transferases for other substituted phosphate groups) inhibitor that interferes with the action of any UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.15), preventing formation of N-acetylglucosamine lipid intermediates and glycosylation of newly synthesised glycoproteins.
EC 2.7.8.15 (UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase) inhibitors
N-acetylglucosamine phosphotransferase inhibitor
N-acetylglucosamine transferase inhibitors
N-acetylglucosamine-1-phosphate transferase inhibitor
N-acetylglucosamine-1-phosphate transferase inhibitors
UDP-D-N-acetylglucosamine N-acetylglucosamine 1-phosphate transferase inhibitor
UDP-D-N-acetylglucosamine N-acetylglucosamine 1-phosphate transferase inhibitors
UDP-GlcNAc:dolichyl-phosphate GlcNAc-1-phosphate transferase inhibitor
UDP-GlcNAc:dolichyl-phosphate GlcNAc-1-phosphate transferase inhibitors
UDP-N-acetyl-D-glucosamine:dolichol phosphate N-acetyl-D-glucosamine-1-phosphate transferase inhibitor
UDP-N-acetyl-D-glucosamine:dolichol phosphate N-acetyl-D-glucosamine-1-phosphate transferase inhibitors
UDP-N-acetyl-D-glucosamine:dolichyl-phosphate N-acetyl-D-glucosaminephosphotransferase inhibitor
UDP-N-acetyl-D-glucosamine:dolichyl-phosphate N-acetyl-D-glucosaminephosphotransferase inhibitors
UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.15) inhibitor
UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.15) inhibitors
UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase inhibitor
UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase inhibitors
UDP-acetylglucosamine--dolichol phosphate acetylglucosamine phosphotransferase inhibitor
UDP-acetylglucosamine--dolichol phosphate acetylglucosamine phosphotransferase inhibitors
UDP-acetylglucosamine--dolichol phosphate acetylglucosamine-1-phosphotransferase inhibitor
UDP-acetylglucosamine--dolichol phosphate acetylglucosamine-1-phosphotransferase inhibitors
chitobiosylpyrophosphoryldolichol synthase inhibitor
chitobiosylpyrophosphoryldolichol synthase inhibitors
dolichol phosphate N-acetylglucosamine-1-phosphotransferase inhibitor
dolichol phosphate N-acetylglucosamine-1-phosphotransferase inhibitors
uridine diphosphoacetylglucosamine--dolichyl phosphate acetylglucosamine-1-phosphotransferase inhibitor
uridine diphosphoacetylglucosamine--dolichyl phosphate acetylglucosamine-1-phosphotransferase inhibitors
Any chemical substance produced during the conversion of a reactant to a product.
A compound which acts as an agonist at the ATP-sensitive K+ channel.
'matrix-assisted laser desorption/ionization' matrix material
'matrix-assisted laser desorption/ionization' matrix materials
A compound used to form the matrix for MALDI (matrix-assisted laser desorption/ionization) mass spectrometry. MALDI matrix materials are crystalline compounds with a fairly low molecular weight, so as to allow facile vaporization, have strong absorption at UV or IR wavelengths (to rapidly and efficiently absorb laser irradiation), generally contain polar groups (enabling them to be used in aqueous solutions) and are frequently acidic (so assisting ionisation of the compound being studied, which is contained within the matrix material).
A neurotransmitter transporter modulator that activates glutamate transporters.
excitatory amino-acid transporter activator
excitatory amino-acid transporter activators
A membrane transport modulator that affects the transport of neurotransmitters.
A cysteine protease inhibitor which inhibits cathepsin K (EC 3.4.22.38).
EC 2.5.1.29 (geranylgeranyl diphosphate synthase) inhibitor
(2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase inhibitor
(2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase inhibitors
An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of geranylgeranyl diphosphate synthase (EC 2.5.1.29).
EC 2.5.1.29 (geranylgeranyl diphosphate synthase) inhibitors
geranylgeranyl diphosphate synthase (EC 2.5.1.29) inhibitor
geranylgeranyl diphosphate synthase (EC 2.5.1.29) inhibitors
geranylgeranyl diphosphate synthase inhibitor
geranylgeranyl diphosphate synthase inhibitors
geranylgeranyl pyrophosphate synthase inhibitor
geranylgeranyl pyrophosphate synthase inhibitors
geranylgeranyl pyrophosphate synthetase inhibitor
geranylgeranyl pyrophosphate synthetase inhibitors
EC 1.3.1.43 (arogenate dehydrogenase) inhibitor
An EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor, NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of arogenate dehydrogenase (EC 1.3.1.43).
EC 1.3.1.43 (arogenate dehydrogenase) inhibitors
L-arogenate:NAD(+) oxidoreductase (decarboxylating) inhibitor
L-arogenate:NAD(+) oxidoreductase (decarboxylating) inhibitors
L-arogenate:NAD+ oxidoreductase (decarboxylating) inhibitor
L-arogenate:NAD+ oxidoreductase (decarboxylating) inhibitors
L-arogenate:NAD+ oxidoreductase inhibitor
L-arogenate:NAD+ oxidoreductase inhibitors
arogenate dehydrogenase (EC 1.3.1.43) inhibitor
arogenate dehydrogenase (EC 1.3.1.43) inhibitors
cyclohexadienyl dehydrogenase inhibitors
A metabolite of plant origin (phytochemical) which acts as a source material for biosynthesis of both lignans and lignin.
EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor
5,10-methylenetetrahydrofolate:glycine hydroxymethyltransferase inhibitor
5,10-methylenetetrahydrofolate:glycine hydroxymethyltransferase inhibitors
An EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor that interferes with the action of glycine hydroxymethyltransferase (EC 2.1.2.1).
EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitors
L-serine hydroxymethyltransferase inhibitor
L-serine hydroxymethyltransferase inhibitors
glycine hydroxymethyltransferase (EC 2.1.2.1) inhibitor
glycine hydroxymethyltransferase (EC 2.1.2.1) inhibitors
glycine hydroxymethyltransferase inhibitor
glycine hydroxymethyltransferase inhibitors
serine hydroxymethyltransferase inhibitor
serine hydroxymethyltransferase inhibitors
An excitatory amino acid agonist which binds to NMDA receptors and triggers a response.
A food additive which is added to flour or dough to improve baking quality and/or colour.
A toxin that accumulates in patients with chronic kidney disease.
Any glycine transporter inhibitor that interferes with the action of glycine 1 transporters.
An agonist that binds to and activates glycine receptors
EC 1.8.1.9 (thioredoxin reductase) inhibitor
An EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of thioredoxin reductase (EC 1.8.1.9).
EC 1.8.1.9 (thioredoxin reductase) inhibitors
NADPH2:oxidized thioredoxin oxidoreductase inhibitor
NADPH2:oxidized thioredoxin oxidoreductase inhibitors
thioredoxin reductase (EC 1.8.1.9) inhibitor
thioredoxin reductase (EC 1.8.1.9) inhibitors
thioredoxin reductase (NADPH) inhibitors
thioredoxin-disulfide reductase inhibitor
thioredoxin-disulfide reductase inhibitors
thioredoxin:NADP+ oxidoreductase inhibitor
thioredoxin:NADP+ oxidoreductase inhibitors
EC 2.3.1.26 (sterol O-acyltransferase) inhibitor
An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of acyl-CoA:cholesterol acyltransferase (EC 2.3.1.26).
EC 2.3.1.26 (sterol O-acyltransferase) inhibitors
acyl coenzyme A-cholesterol-O-acyltransferase inhibitor
acyl coenzyme A-cholesterol-O-acyltransferase inhibitors
acyl-CoA:cholesterol O-acyltransferase inhibitor
acyl-CoA:cholesterol acyltransferase inhibitor
acyl-CoA:cholesterol acyltransferase inhibitors
acylcoenzyme A:cholesterol O-acyltransferase inhibitor
acylcoenzyme A:cholesterol O-acyltransferase inhibitors
sterol O-acyltransferase (EC 2.3.1.26) inhibitor
sterol O-acyltransferase (EC 2.3.1.26) inhibitors
acyl-CoA:cholesterol acyltransferase 2 inhibitor
A sterol O-acyltransferase inhibitor that specifically inhibits acyl-CoA:cholesterol acyltransferase 2.
acyl-CoA:cholesterol acyltransferase 2 inhibitors
EC 3.1.4.11 (phosphoinositide phospholipase C) inhibitor
1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase inhibitor
1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase inhibitors
1-phosphatidyl-D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase inhibitor
1-phosphatidyl-D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase inhibitors
1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase inhibitor
1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase inhibitors
An EC 3.1.4.* (phosphoric diester hydrolase) inhibitor that interferes with the action of phosphatidylinositol-specific phospholipase C (EC 3.1.4.11).
EC 3.1.4.11 (phosphoinositide phospholipase C) inhibitors
monophosphatidylinositol phosphodiesterase inhibitor
monophosphatidylinositol phosphodiesterase inhibitors
phosphatidylinositol phospholipase C inhibitor
phosphatidylinositol phospholipase C inhibitors
phosphatidylinositol-specific phospholipase C inhibitor
phosphatidylinositol-specific phospholipase C inhibitors
phosphoinositide phospholipase C (EC 3.1.4.11) inhibitor
phosphoinositide phospholipase C (EC 3.1.4.11) inhibitors
phosphoinositide phospholipase C inhibitor
phosphoinositide phospholipase C inhibitors
triphosphoinositide phosphodiesterase inhibitor
triphosphoinositide phosphodiesterase inhibitors
The role played by a substance in enhancing the appearance or odour of the human body; a name given to the substance itself or to a component of it.
Any substance that causes disturbance to organisms by chemical reaction or other activity on the molecular scale, when a sufficient quantity is absorbed by the organism.
Any compound that inhibits cell division (mitosis).
A drug used to treat or prevent infections caused by Mycobacteria, a genus of actinobacteria. Aerobic and nonmotile, members of the genus include the pathogens responsible for causing tuberculosis and leprosy.
An antiparasitic drug which is effective against Apicomplexan parasites in the genus Plasmodium. The genus contains over 200 species and includes those responsible for malaria.
EC 2.3.1.20 (diacylglycerol O-acyltransferase) inhibitor
1,2-diacylglycerol acyltransferase inhibitor
1,2-diacylglycerol acyltransferase inhibitors
An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of diacylglycerol O-acyltransferase (EC 2.3.1.20).
EC 2.3.1.20 (diacylglycerol O-acyltransferase) inhibitors
acyl-CoA:1,2-diacylglycerol O-acyltransferase inhibitor
acyl-CoA:1,2-diacylglycerol O-acyltransferase inhibitors
diacylglycerol O-acyltransferase (EC 2.3.1.20) inhibitor
diacylglycerol O-acyltransferase (EC 2.3.1.20) inhibitors
diacylglycerol O-acyltransferase inhibitor
diacylglycerol O-acyltransferase inhibitors
diacylglycerol acyltransferase inhibitor
diacylglycerol acyltransferase inhibitors
diglyceride O-acyltransferase inhibitors
palmitoyl-CoA-sn-1,2-diacylglycerol acyltransferase inhibitor
palmitoyl-CoA-sn-1,2-diacylglycerol acyltransferase inhibitors
An EC 6.5.1.* (DNA/RNA repair enzymes) inhibitor that interferes with the action of DNA ligase (ATP), EC 6.5.1.1.
DNA ligase (ATP) (EC 6.5.1.1) inhibitors
EC 6.5.1.1 (DNA ligase (ATP)) inhibitors
EC 6.5.1.1 [DNA ligase (ATP)] inhibitors
deoxyribonucleic acid joinase inhibitors
deoxyribonucleic acid repair enzyme inhibitor
deoxyribonucleic acid repair enzyme inhibitors
deoxyribonucleic acid-joining enzyme inhibitor
deoxyribonucleic acid-joining enzyme inhibitors
deoxyribonucleic repair enzyme inhibitor
deoxyribonucleic repair enzyme inhibitors
deoxyribonucleic-joining enzyme inhibitor
deoxyribonucleic-joining enzyme inhibitors
polydeoxyribonucleotide synthase (ATP) inhibitor
EC 3.4.21.37 (leukocyte elastase) inhibitor
An EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the activity of leukocyte elastase (EC 3.4.21.37).
EC 3.4.21.37 (leukocyte elastase) inhibitors
leukocyte elastase (EC 3.4.21.37) inhibitor
leukocyte elastase (EC 3.4.21.37) inhibitors
polymorphonuclear leukocyte elastase inhibitor
polymorphonuclear leukocyte elastase inhibitors
An inhibitor of hepatitis C protease, an enzyme required for production of proteins needed for viral assembly.
Any protease inhibitor that restricts the action of a serine protease.
A cysteine protease inhibitor which inhibits cathepsin B (EC 3.4.22.1).
A depigmentation agent which inhibits the synthesis of melanin.
An EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of chymotrypsin (EC 3.4.21.1).
An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus.
An anti-HIV agent that destroys or inhibits the replication of HIV-1, the more infective and more virulent of the two types of HIV virus.
An anti-HIV agent that destroys or inhibits the replication of HIV-2, the less infective and less virulent of the two types of HIV virus.
An antiviral agent that destroys or inhibits the replication of the hepatitis B virus.
An antiviral agent that destroys or inhibits the replication of the herpes simplex virus (also known as the human herpes virus).
An anti-HSV agent agent that destroys or inhibits the replication of herpes simplex virus-1.
An anti-HSV agent agent that destroys or inhibits the replication of herpes simplex virus-2.
An EC 3.2.1.* (glycosidase) inhibitor that interferes with the action of heparanase (EC 3.2.1.166).
heparan sulfate N-sulfo-D-glucosamine endoglucanase inhibitor
heparan sulfate N-sulfo-D-glucosamine endoglucanase inhibitors
An EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of chymase (EC 3.4.21.39).
skeletal muscle (SK) protease inhibitors
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor
A lipoxygenase inhibitor that interferes with the action of arachidonate 5-lipoxygenase (EC 1.13.11.34).
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitors
arachidonate 5-lipoxygenase (EC 1.13.11.34) inhibitor
arachidonate 5-lipoxygenase (EC 1.13.11.34) inhibitors
arachidonic acid 5-lipoxygenase inhibitor
arachidonic acid 5-lipoxygenase inhibitors
EC 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitor
A lipoxygenase inhibitor that interferes with the action of arachidonate 12-lipoxygenase (EC 1.13.11.31).
EC 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitors
arachidonate 12-lipoxygenase (EC 1.13.11.31) inhibitor
arachidonate 12-lipoxygenase (EC 1.13.11.31) inhibitors
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor
A lipoxygenase inhibitor that interferes with the action of arachidonate 15-lipoxygenase (EC 1.13.11.33).
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitors
arachidonate 15-lipoxygenase (EC 1.13.11.33) inhibitor
arachidonate 15-lipoxygenase (EC 1.13.11.33) inhibitors
arachidonate:oxygen 15-oxidoreductase inhibitor
arachidonate:oxygen 15-oxidoreductase inhibitors
linoleic acid omega(6)-lipoxygenase inhibitor
linoleic acid omega(6)-lipoxygenase inhibitors
EC 3.1.1.3 (triacylglycerol lipase) inhibitor
Any EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that inhibits the action of triacylglycerol lipase (EC 3.1.1.3).
EC 3.1.1.3 (triacylglycerol lipase) inhibitors
heparin releasable hepatic lipase inhibitor
heparin releasable hepatic lipase inhibitors
hepatic monoacylglycerol acyltransferase inhibitor
hepatic monoacylglycerol acyltransferase inhibitors
pancreatic triacylglycerol lipase inhibitor
pancreatic triacylglycerol lipase inhibitors
post-heparin plasma protamine-resistant lipase inhibitor
post-heparin plasma protamine-resistant lipase inhibitors
salt-resistant post-heparin lipase inhibitor
salt-resistant post-heparin lipase inhibitors
triacylglycerol ester hydrolase inhibitor
triacylglycerol ester hydrolase inhibitors
triacylglycerol lipase (EC 3.1.1.3) inhibitor
triacylglycerol lipase (EC 3.1.1.3) inhibitors
Any compound that has anti-asthmatic effects.
EC 4.1.1.19 (arginine decarboxylase) inhibitor
An EC 4.1.1.* (carboxy-lyase) inhibitor that interferes with the action of arginine decarboxylase (EC 4.1.1.19).
EC 4.1.1.19 (arginine decarboxylase) inhibitors
L-arginine carboxy-lyase (agmatine-forming) inhibitor
L-arginine carboxy-lyase (agmatine-forming) inhibitors
arginine decarboxylase (EC 4.1.1.19) inhibitor
arginine decarboxylase (EC 4.1.1.19) inhibitors
EC 3.1.3.11 (fructose-bisphosphatase) inhibitor
An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of fructose-bisphosphatase (EC 3.1.3.11).
D-fructose-1,6-bisphosphate 1-phosphohydrolase inhibitor
D-fructose-1,6-bisphosphate 1-phosphohydrolase inhibitors
D-fructose-1,6-bisphosphate phosphatase inhibitor
D-fructose-1,6-bisphosphate phosphatase inhibitors
EC 3.1.3.11 (fructose-bisphosphatase) inhibitors
fructose 1,6-bisphosphate 1-phosphatase inhibitor
fructose 1,6-bisphosphate 1-phosphatase inhibitors
fructose 1,6-bisphosphate phosphatase inhibitor
fructose 1,6-bisphosphate phosphatase inhibitors
fructose 1,6-diphosphate phosphatase inhibitor
fructose 1,6-diphosphate phosphatase inhibitors
fructose bisphosphate phosphatase inhibitor
fructose bisphosphate phosphatase inhibitors
fructose diphosphate phosphatase inhibitor
fructose diphosphate phosphatase inhibitors
fructose-bisphosphatase (EC 3.1.3.11) inhibitor
fructose-bisphosphatase (EC 3.1.3.11) inhibitors
EC 2.1.1.79 (cyclopropane-fatty-acyl-phospholipid synthase) inhibitor
An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of cyclopropane fatty acid synthase (EC 2.1.1.79).
EC 2.1.1.79 (cyclopropane-fatty-acyl-phospholipid synthase) inhibitors
S-adenosyl-L-methionine:unsaturated-phospholipid methyltransferase (cyclising) inhibitor
S-adenosyl-L-methionine:unsaturated-phospholipid methyltransferase (cyclising) inhibitors
S-adenosyl-L-methionine:unsaturated-phospholipid methyltransferase (cyclizing) inhibitor
S-adenosyl-L-methionine:unsaturated-phospholipid methyltransferase (cyclizing) inhibitors
cyclopropane fatty acid synthase inhibitors
cyclopropane fatty acid synthetase inhibitor
cyclopropane fatty acid synthetase inhibitors
cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79) inhibitor
cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79) inhibitors
cyclopropane-fatty-acyl-phospholipid synthase inhibitor
cyclopropane-fatty-acyl-phospholipid synthase inhibitors
unsaturated-phospholipid methyltransferase inhibitor
unsaturated-phospholipid methyltransferase inhibitors
EC 2.1.1.72 [site-specific DNA-methyltransferase (adenine-specific)] inhibitor
An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of site-specific DNA-methyltransferase (adenine-specific), EC 2.1.1.72.
DNA adenine methyltransferase inhibitors
EC 2.1.1.72 (site-specific DNA-methyltransferase (adenine-specific)) inhibitor
EC 2.1.1.72 (site-specific DNA-methyltransferase (adenine-specific)) inhibitors
EC 2.1.1.72 [site-specific DNA-methyltransferase (adenine-specific)] inhibitors
restriction-modification system inhibitor
restriction-modification system inhibitors
site-specific DNA-methyltransferase (adenine-specific) (EC 2.1.1.72) inhibitor
site-specific DNA-methyltransferase (adenine-specific) (EC 2.1.1.72) inhibitors
site-specific DNA-methyltransferase (adenine-specific) inhibitor
site-specific DNA-methyltransferase (adenine-specific) inhibitors
Antipsychotic drugs which can have different modes of action but which tend to be more likely than second generation antipsychotics to cause extrapyramidal motor control disabilities such as body rigidity or Parkinson's disease-type movements; such body movements can become permanent even after treatment has ceased.
Antipsychotic drugs which can have different modes of action but which tend to be less likely than first generation antipsychotics to cause extrapyramidal motor control disabilities such as body rigidity or Parkinson's disease-type movements.
vascular endothelial growth factor receptor antagonist
An antagonist at the vascular endothelial growth factor receptor.
vascular endothelial growth factor receptor antagonists
vascular endothelial growth factor receptor inhibitor
vascular endothelial growth factor receptor inhibitors
An EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of thrombin (EC 3.4.21.5).
activated blood-coagulation factor II inhibitor
activated blood-coagulation factor II inhibitors
EC 3.2.1.114 (mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase) inhibitor
(1->3)-(1->6)-mannosyl-oligosaccharide alpha-D-mannohydrolase inhibitor
(1->3)-(1->6)-mannosyl-oligosaccharide alpha-D-mannohydrolase inhibitors
1,3-(1,6-)mannosyl-oligosaccharide alpha-D-mannohydrolase inhibitor
1,3-(1,6-)mannosyl-oligosaccharide alpha-D-mannohydrolase inhibitors
An enzyme inhibitor that interferes with the action of mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase (EC 3.2.1.114), a key enzyme target in the development of anti-cancer therapies.
EC 3.2.1.114 (mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase) inhibitors
GlcNAc transferase I-dependent alpha1,3[alpha1,6]mannosidase inhibitor
GlcNAc transferase I-dependent alpha1,3[alpha1,6]mannosidase inhibitors
exo-1,3-1,6-alpha-mannosidase inhibitors
mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase (EC 3.2.1.114) inhibitor
mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase (EC 3.2.1.114) inhibitors
mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase inhibitor
mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase inhibitors
An agonist that binds to and activates liver receptor homologue-1 (LRH-1).
nuclear receptor subfamily 5 group A member 2 agonist
nuclear receptor subfamily 5 group A member 2 agonists
Substances which are added to food in order to prevent decomposition caused by microbial growth or by undesirable chemical changes.
A food preservative which prevents decomposition of food by preventing the growth of fungi or bacteria. In European countries, E-numbers for permitted food preservatives are from E200 to E299, divided into sorbates (E200-209), benzoates (E210-219), sulfites (E220-229), phenols and formates (E230-239), nitrates (E240-259), acetates (E260-269), lactates (E270-279), propionates (E280-289) and others (E290-299).
A compound that inhibits the action of gamma-aminobutyric acid.
gamma-aminobutyric acid receptor antagonist
gamma-aminobutyric acid receptor antagonists
Any substance which is used to neutralise stomach acidity.
An agonist that binds to and activates erythropeotin receptors.
An agonist that binds to and activates prostaglandin receptors.
A membrane transport modulator that restores the chloride ion transport ability of defective cystic fibrosis transmembrane conductance regulator (CFTR) genes.
cystic fibrosis transmembrane conductance regulator potentiator
cystic fibrosis transmembrane conductance regulator potentiators
An antagonist that interferes with the action of smoothened (SMO) receptor.
Any compound which can be used to treat or alleviate the symptoms of dyskinesia.
Any compound that improves mental functions such as cognition, memory, intelligence, motivation, attention, and concentration.
Any compound used for the treatment of eye conditions or eye diseases.
Any compound that is able to protect normal cells from the damage caused by radiation therapy.
Any compound which inhibits the postganglionic functioning of the sympathetic nervous system (SNS).
Any compound used to suppress premature labour and immature birth by suppressing uterine contractions.
An agonist that binds to and activates cannabinoid receptors.
Any compound that has anti-inflammatory effects.
A chemosterilant intended to sterilize insects.
A ryanodine receptor modulator which activates the receptor. Ryanodine receptors (RyRs) act as selective ion channels, modulating the release of calcium. Activating the receptors causes the release of calcium, so depleting internal calcium and ultimately preventing further muscle contraction.
A reagent used in the determination of the concentration of a coloured chemical element or chemical compound in solution.
In NMR spectroscopy a reagent added to a solution to induce chemical shifts and thus simplify complex spectra.
nuclear magnetic resonance shift reagent
nuclear magnetic resonance shift reagents
EC 3.4.24.3 (microbial collagenase) inhibitor
Achromobacter iophagus collagenase inhibitor
Achromobacter iophagus collagenase inhibitors
An EC 3.4.24.* (metalloendopeptidase) inhibitor which interferes with the action of microbial collagenase (EC 3.4.24.3, also formerly EC 3.4.4.19 and EC 3.4.99.5).
Clostridium histolyticum collagenase inhibitor
Clostridium histolyticum collagenase inhibitors
Clostridium histolyticum proteinase A inhibitor
Clostridium histolyticum proteinase A inhibitors
EC 3.4.24.3 (microbial collagenase) inhibitors
microbial collagenase (EC 3.4.24.3) inhibitor
microbial collagenase (EC 3.4.24.3) inhibitors
gap junctional intercellular communication inhibitor
An inhibitor that interferes with the process of gap junctional intercellular communication.
gap junctional intercellular communication inhibitors
An agonist that selectively binds to and activates a retinoic acid receptor.
An antogonist that interferes with the action of activator protein 1 (AP-1).
A provitamin that can be converted into vitamin A by enzymes from animal tissues.
EC 3.2.1.45 (glucosylceramidase) inhibitor
An EC 3.2.1.* (glycosidase) inhibitor that interferes with the action of glucosylceramidase (EC 3.2.1.45).
D-glucosyl-N-acylsphingosine glucohydrolase inhibitor
D-glucosyl-N-acylsphingosine glucohydrolase inhibitors
EC 3.2.1.45 (glucosylceramidase) inhibitors
glucosphingosine glucosylhydrolase inhibitor
glucosphingosine glucosylhydrolase inhibitors
glucosylceramidase (EC 3.2.1.45) inhibitor
glucosylceramidase (EC 3.2.1.45) inhibitors
glucosylsphingosine beta-D-glucosidase inhibitor
glucosylsphingosine beta-D-glucosidase inhibitors
glucosylsphingosine beta-glucosidase inhibitor
glucosylsphingosine beta-glucosidase inhibitors
EC 3.2.1.48 (sucrose alpha-glucosidase) inhibitor
An EC 3.2.1.* (glycosidase) inhibitor that interferes with the action of sucrose alpha-glucosidase (EC 3.2.1.48).
EC 3.2.1.48 (sucrose alpha-glucosidase) inhibitors
sucrose alpha-glucosidase (EC 3.2.1.48) inhibitor
sucrose alpha-glucosidase (EC 3.2.1.48) inhibitors
sucrose-alpha-D-glucohydrolase inhibitor
sucrose-alpha-D-glucohydrolase inhibitors
EC 3.2.1.10 (oligo-1,6-glucosidase) inhibitor
An EC 3.2.1.* (glycosidase) inhibitor that inhibits the action of sucrose oligo-1,6-glucosidase (EC 3.2.1.10).
EC 3.2.1.10 (oligo-1,6-glucosidase) inhibitors
dextrin 6alpha-glucanohydrolase inhibitor
dextrin 6alpha-glucanohydrolase inhibitors
oligo-1,6-glucosidase (EC 3.2.1.10) inhibitor
oligo-1,6-glucosidase (EC 3.2.1.10) inhibitors
oligosaccharide alpha-1,6-glucohydrolase inhibitor
oligosaccharide alpha-1,6-glucohydrolase inhibitors
EC 3.2.1.20 (alpha-glucosidase) inhibitor
An EC 3.2.1.* (glycosidase) inhibitor that interferes with the action of alpha-glucosidase (EC 3.2.1.20).
EC 3.2.1.20 (alpha-glucosidase) inhibitors
alpha-glucosidase (EC 3.2.1.20) inhibitor
alpha-glucosidase (EC 3.2.1.20) inhibitors
EC 2.5.1.59 (protein geranylgeranyltransferase type I) inhibitor
An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of protein geranylgeranyltransferase type I (EC 2.5.1.59).
EC 2.5.1.59 (protein geranylgeranyltransferase type I) inhibitors
geranylgeranyl-diphosphate:protein-cysteine geranyltransferase inhibitor
geranylgeranyl-diphosphate:protein-cysteine geranyltransferase inhibitors
geranylgeranyltransferase type I inhibitor
geranylgeranyltransferase type I inhibitors
protein geranylgeranyltransferase type I (EC 2.5.1.59) inhibitor
protein geranylgeranyltransferase type I (EC 2.5.1.59) inhibitors
protein geranylgeranyltransferase type I inhibitor
protein geranylgeranyltransferase type I inhibitors
An inhibitor of HIV-1 integrase, an enzyme required for the integration of the genetic material of the retrovirus into the DNA of the infected cells.
A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
A protein kinase inhibitor of the mammalian target of rapamycin (mTOR), a protein that regulates cell growth, cell proliferation, cell motility, cell survival, protein synthesis and transcription. mTOR inhibitors are used to prevent transplant rejection and in treatment of cancer.
mammalian target of rapamycin inhibitors
Any substance that inhibits the process of apoptosis (programmed cell death) in multi-celled organisms.
Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
A compound which causes a reduction in the levels of glutathione in cells.
EC 1.3.98.1 [dihydroorotate oxidase (fumarate)] inhibitor
(S)-dihydroorotate:fumarate oxidoreductase inhibitor
(S)-dihydroorotate:fumarate oxidoreductase inhibitors
An EC 1.3.98.* (oxidoreductase acting on CH-CH group of donors, with other, known, acceptors) inhibitor that interferes with the action of dihydroorotate oxidase (fumarate), EC 1.3.98.1 (formerly EC 1.3.3.1).
EC 1.3.98.1 (dihydroorotate oxidase (fumarate)) inhibitor
EC 1.3.98.1 (dihydroorotate oxidase (fumarate)) inhibitors
EC 1.3.98.1 [dihydroorotate oxidase (fumarate)] inhibitors
dihydroorotate oxidase (fumarate) (EC 1.3.98.1) inhibitor
dihydroorotate oxidase (fumarate) (EC 1.3.98.1) inhibitors
dihydroorotate oxidase (fumarate) inhibitor
dihydroorotate oxidase (fumarate) inhibitors
A pathway inhibitor that inhibits the synthesis of pyrimidine.
An agonist that selectively binds to and activates guanylate cyclase 2C receptors.
An antagonist at the bradykinin receptor.
purinergic receptor subtype P2Y12 antagonist
purinergic receptor subtype P2Y12 antagonists
EC 3.4.21.6 (coagulation factor Xa) inhibitor
An EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of coagulation factor Xa (EC 3.4.21.6).
EC 3.4.21.6 (coagulation factor Xa) inhibitors
activated Stuart-Prower factor inhibitor
activated Stuart-Prower factor inhibitors
activated blood-coagulation factor X inhibitor
activated blood-coagulation factor X inhibitors
coagulation factor Xa (EC 3.4.21.6) inhibitor
coagulation factor Xa (EC 3.4.21.6) inhibitors
EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor
An EC 3.4.14.* (dipeptidyl- and tripeptidyl-peptidases) inhibitor that specifically inhibits dipeptidyl peptidase-4 (EC 3.4.14.5).
EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitors
T cell triggering molecule Tp103 inhibitor
T cell triggering molecule Tp103 inhibitors
X-prolyl dipeptidyl aminopeptidase inhibitor
X-prolyl dipeptidyl aminopeptidase inhibitors
Xaa-Pro-dipeptidyl-aminopeptidase inhibitor
Xaa-Pro-dipeptidyl-aminopeptidase inhibitors
amino acyl-prolyl dipeptidyl aminopeptidase inhibitor
amino acyl-prolyl dipeptidyl aminopeptidase inhibitors
dipeptidyl-peptidase IV (EC 3.4.14.5) inhibitor
dipeptidyl-peptidase IV (EC 3.4.14.5) inhibitors
glycylprolyl dipeptidylaminopeptidase inhibitor
glycylprolyl dipeptidylaminopeptidase inhibitors
postproline dipeptidyl aminopeptidase IV inhibitor
postproline dipeptidyl aminopeptidase IV inhibitors
EC 1.14.99.9 (steroid 17alpha-monooxygenase) inhibitor
17-alpha-hydroxylase/C17,20-lyase inhibitor
17-alpha-hydroxylase/C17,20-lyase inhibitors
17alpha-hydroxylase-C17,20 lyase inhibitor
17alpha-hydroxylase-C17,20 lyase inhibitors
An EC 1.14.99.* (miscellaneous oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of cytochrome P450 17-alpha-hydroxylase/C17,20-lyase (EC 1.14.99.9).
EC 1.14.99.9 (steroid 17alpha-monooxygenase) inhibitors
cytochrome P450 (P-45017alpha,lyase) inhibitor
cytochrome P450 (P-45017alpha,lyase) inhibitors
cytochrome P450 17-alpha-hydroxylase/C17,20-lyase inhibitor
cytochrome P450 17-alpha-hydroxylase/C17,20-lyase inhibitors
steroid 17alpha-monooxygenase (EC 1.14.99.9) inhibitor
steroid 17alpha-monooxygenase (EC 1.14.99.9) inhibitors
steroid 17alpha-monooxygenase inhibitors
steroid 17alphahydroxylase/17,20 lyase inhibitor
steroid 17alphahydroxylase/17,20 lyase inhibitors
steroid,NADPH--hemoprotein reductase:oxygen oxidoreductase (17alpha-hydroxylating) inhibitor
steroid,NADPH--hemoprotein reductase:oxygen oxidoreductase (17alpha-hydroxylating) inhibitors
An EC 3.1.4.53 (3',5'-cyclic-AMP phosphodiesterase) inhibitor that specifically blocks the action of phosphodiesterase IV.
An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
A hormone agonist that binds to and activates progesterone receptors.
EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor
An EC 6.4.1.* (C-C bond-forming ligase) inhibitor that interferes with the action of acetyl-CoA carboxylase (EC 6.4.1.2).
EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitors
acetyl coenzyme A carboxylase inhibitors
acetyl-CoA carboxylase (EC 6.4.1.2) inhibitor
acetyl-CoA carboxylase (EC 6.4.1.2) inhibitors
acetyl-CoA:carbon-dioxide ligase (ADP-forming) inhibitor
acetyl-CoA:carbon-dioxide ligase (ADP-forming) inhibitors
Any compound which induces a partially or terminally differentiated cell to revert to an earlier developmental stage.
An EC 5.99.1.* (miscellaneous isomerase) inhibitor that interferes with the action of any of the topoisomerases (enzymes that regulate the overwinding or underwinding of DNA).
Any substance that inhibits the polymerisation of the protein actin.
Any protein kinase inhibitor that inhibits the action of an Aurora kinase (a group of serine/threonine kinases that are essential for cell proliferation).
Any substance which blocks the painful sensation of heat caused by capsaicin acting on the TRPV1 ion channel.
transient receptor potential cation channel subfamily V member 1 antagonist
transient receptor potential cation channel subfamily V member 1 antagonists
Any compound which acts on the peroxisome proliferator-activated receptor.
peroxisome proliferator-activated receptor modulator
peroxisome proliferator-activated receptor modulators
A PPAR modulator which activates the peroxisome proliferator-activated receptor-alpha.
peroxisome proliferator-activated receptor-alpha agonist
peroxisome proliferator-activated receptor-alpha agonists
EC 1.2.1.12 [glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)] inhibitor
3-phosphoglyceraldehyde dehydrogenase inhibitor
3-phosphoglyceraldehyde dehydrogenase inhibitors
An EC 1.2.1.* (oxidoreductase acting on donor aldehyde/oxo group with NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12).
D-glyceraldehyde-3-phosphate:NAD(+) oxidoreductase (phosphorylating) inhibitor
D-glyceraldehyde-3-phosphate:NAD(+) oxidoreductase (phosphorylating) inhibitors
EC 1.2.1.12 (glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)) inhibitor
EC 1.2.1.12 (glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)) inhibitors
EC 1.2.1.12 [glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)] inhibitors
NAD-dependent glyceraldehyde phosphate dehydrogenase inhibitor
NAD-dependent glyceraldehyde phosphate dehydrogenase inhibitors
NADH-glyceraldehyde phosphate dehydrogenase inhibitor
NADH-glyceraldehyde phosphate dehydrogenase inhibitors
dehydrogenase, glyceraldehyde phosphate inhibitor
dehydrogenase, glyceraldehyde phosphate inhibitors
glyceraldehyde phosphate dehydrogenase (NAD) inhibitor
glyceraldehyde phosphate dehydrogenase (NAD) inhibitors
glyceraldehyde-3-P-dehydrogenase inhibitor
glyceraldehyde-3-P-dehydrogenase inhibitors
glyceraldehyde-3-phosphate dehydrogenase (NAD) inhibitor
glyceraldehyde-3-phosphate dehydrogenase (NAD) inhibitors
glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) (EC 1.2.1.12) inhibitor
glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) (EC 1.2.1.12) inhibitors
glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) inhibitor
glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) inhibitors
glyceraldehyde-3-phosphate dehydrogenase inhibitor
glyceraldehyde-3-phosphate dehydrogenase inhibitors
phosphoglyceraldehyde dehydrogenase inhibitor
phosphoglyceraldehyde dehydrogenase inhibitors
triosephosphate dehydrogenase inhibitors
Aldrichina grahami cysteine proteinase inhibitor
Aldrichina grahami cysteine proteinase inhibitors
An EC 3.4.22.* (cysteine endopeptidase) inhibitor which interferes with the action of cathepsin L (EC 3.4.22.15).
A cysteine protease inhibitor which inhibits papain (EC 3.4.22.2).
An antiprotozoal drug used to treat or prevent infections caused by protozoan parasites that belong to the genus Leishmania.
Any entity used to generate reactive oxygen species.
An agonist that binds to and activates G-protein-coupled receptors
alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonist
alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonists
A hormone receptor modulator that acts as a complete or partial agonist or as an antagonist at the progesterone receptor.
Any drug that has been developed specifically for treatment of a rare medical condition, the condition itself being known as an orphan disease.
carbamylphosphate synthetase I activator
Any compound that binds and activates the enzyme carbamylphosphate synthetase I.
carbamylphosphate synthetase I activators
A compound that blocks the processing of the Gag precursor protein in HIV-1 by the viral protease enzyme, leading to the formation of noninfectious, immature virus particles that are incapable of infecting other cells.
A histamine agonist that binds to and activates H1-receptors.
EC 2.1.1.4 (acetylserotonin O-methyltransferase) inhibitor
An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of N-acetylserotonin methyltransferase (EC 2.1.1.4).
EC 2.1.1.4 (acetylserotonin O-methyltransferase) inhibitors
N-acetylserotonin O-methyltransferase inhibitor
N-acetylserotonin O-methyltransferase inhibitors
N-acetylserotonin methyltransferase inhibitor
N-acetylserotonin methyltransferase inhibitors
S-adenosyl-L-methionine:N-acetylserotonin O-methyltransferase inhibitor
S-adenosyl-L-methionine:N-acetylserotonin O-methyltransferase inhibitors
acetylserotonin O-methyltransferase (EC 2.1.1.4) inhibitor
acetylserotonin O-methyltransferase (EC 2.1.1.4) inhibitors
acetylserotonin O-methyltransferase inhibitor
acetylserotonin O-methyltransferase inhibitors
acetylserotonin methyltransferase inhibitor
acetylserotonin methyltransferase inhibitors
hydroxyindole O-methyltransferase inhibitor
hydroxyindole O-methyltransferase inhibitors
hydroxyindole methyltransferase inhibitor
hydroxyindole methyltransferase inhibitors
An EC 3.5.1.98 (histone deacetylase) inhibitor that interferes with the action of Sir2.
glucagon-like peptide-1 receptor agonist
An agonist that binds to and activates glucagon-like peptide-1 (GLP-1) receptors.
glucagon-like peptide-1 receptor agonists
Any intra-glandular substance that acts as a precursor of a hormone, usually having minimal hormonal effect itself. Prohormones generally help in amplifying the effect of existing hormones.
An antagonist at any adenosine receptor.
An enzyme inhibitor that inhibits the action of a transferase (EC 2.*)
A signalling molecule produced and used by bacteria participating in quorum sensing, that is, in cell-cell communication to coordinate community-wide regulation of processes such as biofilm formation, virulence, and bioluminescence in populations of bacteria. Such communication can occur both within and between different species of bacteria.
EC 2.3.1.85 (fatty acid synthase) inhibitor
An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of fatty acid synthase (EC 2.3.1.85), a multi-enzyme protein involved in fatty acid synthesis.
EC 2.3.1.85 (fatty acid synthase) inhibitors
acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing) inhibitor
acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing) inhibitors
fatty acid synthase (EC 2.3.1.85) inhibitor
fatty acid synthase (EC 2.3.1.85) inhibitors
An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of ceramidase (EC 3.5.1.23).
N-acylsphingosine amidohydrolase inhibitor
N-acylsphingosine amidohydrolase inhibitors
glycosphingolipid ceramide deacylase inhibitor
glycosphingolipid ceramide deacylase inhibitors
A PPAR modulator which activates the peroxisome proliferator-activated receptor-gamma.
peroxisome proliferator-activated receptor-gamma agonist
peroxisome proliferator-activated receptor-gamma agonists
An insecticide that acts as a repellent to insects.
EC 3.1.4.35 (3',5'-cyclic-GMP phosphodiesterase) inhibitor
3',5'-cyclic-GMP 5'-nucleotidohydrolase inhibitor
3',5'-cyclic-GMP 5'-nucleotidohydrolase inhibitors
3',5'-cyclic-GMP phosphodiesterase (EC 3.1.4.35) inhibitor
3',5'-cyclic-GMP phosphodiesterase (EC 3.1.4.35) inhibitors
An EC 3.1.4.* (phosphoric diester hydrolase) inhibitor that blocks the action of 3',5'-cyclic-GMP phosphodiesterase (EC 3.1.4.35).
EC 3.1.4.35 (3',5'-cyclic-GMP phosphodiesterase) inhibitors
cyclic 3',5'-GMP phosphodiesterase inhibitor
cyclic 3',5'-GMP phosphodiesterase inhibitors
cyclic guanosine 3',5'-monophosphate phosphodiesterase inhibitor
cyclic guanosine 3',5'-monophosphate phosphodiesterase inhibitors
cyclic guanosine 3',5'-phosphate phosphodiesterase inhibitor
cyclic guanosine 3',5'-phosphate phosphodiesterase inhibitors
guanosine cyclic 3',5'-phosphate phosphodiesterase inhibitor
guanosine cyclic 3',5'-phosphate phosphodiesterase inhibitors
EC 3.5.1.88 (peptide deformylase) inhibitor
An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of peptide deformylase (EC 3.5.1.88), involved in the catalytic removal of the N-terminal formyl group of nascent proteins.
EC 3.5.1.88 (peptide deformylase) inhibitors
formyl-L-methionyl peptide amidohydrolase inhibitor
formyl-L-methionyl peptide amidohydrolase inhibitors
peptide deformylase (EC 3.5.1.88) inhibitor
peptide deformylase (EC 3.5.1.88) inhibitors
Any molecule shown to have the potentiality in stimulating the effect of nerve growth factor.
An inhibitor that interferes with the action of MTP.
microsomal triglyceride transfer protein inhibitor
microsomal triglyceride transfer protein inhibitors
glucagon-like peptide-2 receptor agonist
An agonist that binds to and activates glucagon-like peptide-2 (GLP-2) receptors.
glucagon-like peptide-2 receptor agonists
Any toxin secreted by bacteria, viruses, fungi or protozoa enabling them to achieve colonisation of a niche in the host, inhibit or evade the host's immune response, enter and exit cells, or obtain nutrition from the host.
A provitamin that can be converted into vitamin B1 by enzymes from animal tissues.
An inhibitor that interferes with vesicular glutamate transport.
vesicular glutamate transport inhibitors
vesicular glutamate transporter 1 inhibitor
vesicular glutamate transporter 1 inhibitors
Any compound that promotes the growth of new blood vessels from pre-existing vessels.
A pheromone which is released by an organism when damaged by a predator which warns other individuals that there is a danger.
EC 2.3.2.13 (protein-glutamine gamma-glutamyltransferase) inhibitor
An EC 2.3.2.* (aminoacyltransferase) inhibitor that interferes with the action of protein-glutamine gamma-glutamyltransferase (EC 2.3.2.13).
EC 2.3.2.13 (protein-glutamine gamma-glutamyltransferase) inhibitors
R-glutaminyl-peptide:amine gamma-glutamyl transferase inhibitor
glutaminylpeptide gamma-glutamyltransferase inhibitor
glutaminylpeptide gamma-glutamyltransferase inhibitors
protein-glutamine gamma-glutamyltransferase (EC 2.3.2.13) inhibitor
protein-glutamine gamma-glutamyltransferase (EC 2.3.2.13) inhibitors
protein-glutamine gamma-glutamyltransferase inhibitor
protein-glutamine gamma-glutamyltransferase inhibitors
protein-glutamine:amine gamma-glutamyltransferase inhibitor
protein-glutamine:amine gamma-glutamyltransferase inhibitors
An agonist that binds to and activates aryl hydrocarbon receptors (AhRs).
breast cancer resistance protein inhibitor
Any inhibitor of breast cancer resistance protein (ABCG2).
breast cancer resistance protein inhibitors
Any inhibitor of the biosynthesis of carotenoids.
EC 1.3.99.29 [phytoene desaturase (zeta-carotene-forming)] inhibitor
15-cis-phytoene:acceptor oxidoreductase (zeta-carotene-forming) inhibitor
15-cis-phytoene:acceptor oxidoreductase (zeta-carotene-forming) inhibitors
An EC 1.3.99.* (oxidoreductase acting on donor CH-CH group with other acceptors) inhibitor that interferes with the action of phytoene desaturase (zeta-carotene-forming), EC 1.3.99.29, an enzyme of carotenoid biosynthesis that converts phytoene into zeta-carotene (zeta-carotene) via the symmetrical introduction of two double bonds at the C-11 and C-11' positions of phytoene.
EC 1.3.99.29 [phytoene desaturase (zeta-carotene-forming)] inhibitors
phytoene desaturase (zeta-carotene-forming) (EC 1.3.99.29) inhibitor
phytoene desaturase (zeta-carotene-forming) (EC 1.3.99.29) inhibitors
phytoene desaturase (zeta-carotene-forming) inhibitor
phytoene desaturase (zeta-carotene-forming) inhibitors
EC 1.13.11.52 (indoleamine 2,3-dioxygenase) inhibitor
An EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 atoms of oxygen) inhibitor that interferes with the action of indoleamine 2,3-dioxygenase (EC 1.13.11.52).
D-tryptophan:oxygen 2,3-oxidoreductase (decyclizing) inhibitor
D-tryptophan:oxygen 2,3-oxidoreductase (decyclizing) inhibitors
EC 1.13.11.52 (indoleamine 2,3-dioxygenase) inhibitors
indoleamine 2,3-dioxygenase (EC 1.13.11.52) inhibitor
indoleamine 2,3-dioxygenase (EC 1.13.11.52) inhibitors
EC 1.1.1.184 [carbonyl reductase (NADPH)] inhibitor
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of carbonyl reductase (NADPH), EC 1.1.1.184.
EC 1.1.1.184 (carbonyl reductase (NADPH)) inhibitor
EC 1.1.1.184 (carbonyl reductase (NADPH)) inhibitors
EC 1.1.1.184 [carbonyl reductase (NADPH)] inhibitors
NADPH2-dependent carbonyl reductase inhibitor
NADPH2-dependent carbonyl reductase inhibitors
carbonyl reductase (NADPH) (EC 1.1.1.184) inhibitor
carbonyl reductase (NADPH) (EC 1.1.1.184) inhibitors
nonspecific NADPH-dependent carbonyl reductase inhibitor
nonspecific NADPH-dependent carbonyl reductase inhibitors
prostaglandin 9-ketoreductase inhibitors
secondary-alcohol:NADP+ oxidoreductase inhibitor
secondary-alcohol:NADP+ oxidoreductase inhibitors
EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor
An EC 1.11.1.* (peroxidases) inhibitor that inhibits the action of L-ascorbate peroxidase (EC 1.11.1.11).
EC 1.11.1.11 (L-ascorbate peroxidase) inhibitors
L-ascorbate peroxidase (EC 1.11.1.11) inhibitor
L-ascorbate peroxidase (EC 1.11.1.11) inhibitors
L-ascorbate:hydrogen-peroxide oxidoreductase inhibitor
L-ascorbate:hydrogen-peroxide oxidoreductase inhibitors
L-ascorbic acid-specific peroxidase inhibitor
L-ascorbic acid-specific peroxidase inhibitors
Any compound that protects plants by activating their defence mechanisms.
Any compound that inhibits one or more steps in the pathway leading to the synthesis of brassinosteroids.
An agent that reduces or interferes with the mutagenic actions or effects of a substance.
An agonist that binds to and activates abscisic acid receptors.
EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor
An EC 1.3.3.* (oxidoreductase acting on donor CH-CH group with oxygen as acceptor) inhibitor that interferes with the action of protoporphyrinogen oxidase (EC 1.3.3.4).
EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitors
protoporphyrinogen IX oxidase inhibitors
protoporphyrinogen oxidase (EC 1.3.3.4) inhibitor
protoporphyrinogen oxidase (EC 1.3.3.4) inhibitors
protoporphyrinogen-IX:oxygen oxidoreductase inhibitor
protoporphyrinogen-IX:oxygen oxidoreductase inhibitors
Any compound that inhibits one or more steps in the pathway leading to the synthesis of gibberellins.
EC 4.4.1.11 (methionine gamma-lyase) inhibitor
An EC 4.4.1.* (C-S lyase) inhibitor that interferes with the action of the enzyme methionine gamma-lyase (EC 4.4.1.11).
EC 4.4.1.11 (methionine gamma-lyase) inhibitors
methionine gamma-lyase (EC 4.4.1.11) inhibitor
methionine gamma-lyase (EC 4.4.1.11) inhibitors
EC 3.6.3.14 (H(+)-transporting two-sector ATPase) inhibitor
ATP phosphohydrolase (H(+)-transporting) inhibitor
ATP phosphohydrolase (H(+)-transporting) inhibitors
An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of H(+)-transporting two-sector ATPase inhibitor (EC 3.6.3.14).
EC 3.6.3.14 (H(+)-transporting two-sector ATPase) inhibitors
H(+)-transporting two-sector ATPase (EC 3.6.3.14) inhibitor
H(+)-transporting two-sector ATPase (EC 3.6.3.14) inhibitors
H(+)-transporting two-sector ATPase inhibitor
H(+)-transporting two-sector ATPase inhibitors
bacterial Ca(2+)/Mg(2+) ATPase inhibitor
bacterial Ca(2+)/Mg(2+) ATPase inhibitors
coupling factors (Fo, F1 and CF1) inhibitor
coupling factors (Fo, F1 and CF1) inhibitors
EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor
Any hydrolase inhibitor that interferes with the action of a hydrolase which acts on acid anhydrides (EC 3.6.*.*).
EC 3.6.* (hydrolases acting on acid anhydrides) inhibitors
inhibitor of hydrolase acting on acid anhydride (EC 3.6.*)
inhibitors of hydrolase acting on acid anhydride (EC 3.6.*)
An inhibitor of NF-kappaB (nuclear factor kappa-light-chain-enhancer of activated B cells), a protein complex involved in the transcription of DNA.
nuclear factor kappa-light-chain-enhancer of activated B cells inhibitor
nuclear factor kappa-light-chain-enhancer of activated B cells inhibitors
A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 3.
Any compound that inhibits oxidative phosphorylation.
sodium-glucose transport protein subtype 2 inhibitor
Any inhibitor that interferes with the action of sodium-glucose transport protein subtype 2.
sodium glucose co-transporter 2 inhibitor
sodium glucose co-transporter 2 inhibitors
sodium-glucose transport protein subtype 2 inhibitors
sodium/glucose cotransporter 2 inhibitor
sodium/glucose cotransporter 2 inhibitors
A hormone antagonist that inhibits the action of the peptide hormone cholecystokinin.
An agonist at the adenosine A3 receptor.
An acaricide that kills mites of the genus Sarcoptes.
A hormone agonist that binds to and activates a thyroid hormone receptor.
A photochemical role realized in the absorption of ultraviolet light, for example to protect skin cells from damage.
A drug used in treating and healing of wounds.
Any agent used to determine the amino-acid sequence in a polypeptide.
An EC 2.7.3.* (phosphotransferases with a nitrogenous group as acceptor) inhibitor that interferes with the action of creatine kinase, EC 2.7.3.2.
EC 3.4.11.18 (methionyl aminopeptidase) inhibitor
Any EC 3.4.11.* (aminopeptidase) inhibitor that interferes with the action of methionyl aminopeptidase (EC 3.4.11.18).
EC 3.4.11.18 (methionyl aminopeptidase) inhibitors
methionyl aminopeptidase (EC 3.4.11.18) inhibitor
methionyl aminopeptidase (EC 3.4.11.18) inhibitors
Any methionyl aminopeptidase inhibitor that inhibits the action of methionyl aminopeptidase 2.
An antagonist that binds to and deactivates cannabinoid receptors.
An antagonist that binds to and deactivates type 1 cannabinoid receptors.
An antagonist that binds to and deactivates type 2 cannabinoid receptors.
A member of the class of kynurenamines that is aniline substituted at position 2 by a 3-aminopropanoyl group.
A reagent used in the determination by spectrophotometry of the concentration of a chemical element or chemical compound in solution.
A substance that invokes a specific immune non-responsiveness due to its molecular form. If its molecular form is changed, a tolerogen can become an immunogen.
A reagent used to couple amino acids during artificial peptide synthesis.
A PPAR modulator which activates the peroxisome proliferator-activated receptor-beta/delta.
nuclear receptor subfamily 1, group C, member 2 agonist
nuclear receptor subfamily 1, group C, member 2 agonists
peroxisome proliferator-activated receptor-beta agonist
peroxisome proliferator-activated receptor-beta agonists
peroxisome proliferator-activated receptor-delta agonist
peroxisome proliferator-activated receptor-delta agonists
Any compound that inhibits the growth of bacteria of the genus Vibrio.
An antimetabolite that impairs the action of folic acids
Any compound that binds to and activates the enzyme nitric oxide synthase (EC 1.14.13.39).
Any substance that stimulates the corneal nerves in the eves to cause tears.
Substance used to set dyes on fabrics or tissue sections by forming a coordination complex with the dye which then attaches to the fabric or tissue.
EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor
2'-deoxyribonucleoside-diphosphate:thioredoxin-disulfide 2'-oxidoreductase inhibitor
2'-deoxyribonucleoside-diphosphate:thioredoxin-disulfide 2'-oxidoreductase inhibitors
An EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitor that inhibits the action of ribonucleoside-diphosphate reductase (EC 1.17.4.1).
EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitors
nucleoside diphosphate reductase inhibitor
nucleoside diphosphate reductase inhibitors
ribonucleoside diphosphate reductase inhibitor
ribonucleoside diphosphate reductase inhibitors
ribonucleoside-diphosphate reductase (EC 1.17.4.1) inhibitor
ribonucleoside-diphosphate reductase (EC 1.17.4.1) inhibitors
ribonucleoside-diphosphate reductase inhibitor
ribonucleoside-diphosphate reductase inhibitors
ribonucleotide diphosphate reductase inhibitor
ribonucleotide diphosphate reductase inhibitors
EC 1.1.1.153 [sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)] inhibitor
7,8-dihydrobiopterin:NADP(+) oxidoreductase
7,8-dihydrobiopterin:NADP(+) oxidoreductases
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the activity of sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming), EC 1.1.1.153, which plays an important part in the biosynthesis of tetrahydrobiopterin.
EC 1.1.1.153 (sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)) inhibitor
EC 1.1.1.153 (sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)) inhibitors
EC 1.1.1.153 [sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)] inhibitors
L-erythro-7,8-dihydrobiopterin:NADP(+) oxidoreductase inhibitor
L-erythro-7,8-dihydrobiopterin:NADP(+) oxidoreductase inhibitors
sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming) (EC 1.1.1.153) inhibitor
sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming) (EC 1.1.1.153) inhibitors
sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming) inhibitor
sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming) inhibitors
Any compound used as a monomer for a polymerisation process. The term is generally used in relation to industrial polymerisation processes.
An compound that inhibits quinol oxidation sites.
epidermal growth factor receptor antagonist
An antagonist at the epidermal growth factor receptor.
epidermal growth factor receptor antagonists
epidermal growth factor receptor inhibitor
epidermal growth factor receptor inhibitors
Any substance which is used to reduce or control weight.
EC 1.1.1.44 (NADP(+)-dependent decarboxylating phosphogluconate dehydrogenase) inhibitor
6-phospho-D-gluconate dehydrogenase inhibitor
6-phospho-D-gluconate dehydrogenase inhibitors
6-phospho-D-gluconate:NADP+ 2-oxidoreductase (decarboxylating) inhibitor
6-phospho-D-gluconate:NADP+ 2-oxidoreductase (decarboxylating) inhibitors
6-phosphogluconate dehydrogenase (decarboxylating) inhibitor
6-phosphogluconate dehydrogenase (decarboxylating) inhibitors
6-phosphogluconic carboxylase inhibitors
6-phosphogluconic dehydrogenase inhibitor
6-phosphogluconic dehydrogenase inhibitors
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of NADP(+)-dependent decarboxylating phosphogluconate dehydrogenase (EC 1.1.1.44).
EC 1.1.1.44 (NADP(+)-dependent decarboxylating phosphogluconate dehydrogenase) inhibitors
NADP(+)-dependent decarboxylating phosphogluconate dehydrogenase (EC 1.1.1.44) inhibitor
NADP(+)-dependent decarboxylating phosphogluconate dehydrogenase (EC 1.1.1.44) inhibitors
NADP(+)-dependent decarboxylating phosphogluconate dehydrogenase inhibitor
NADP(+)-dependent decarboxylating phosphogluconate dehydrogenase inhibitors
phosphogluconate dehydrogenase (NADP+ -dependent, decarboxylating) inhibitor
phosphogluconate dehydrogenase (NADP+ -dependent, decarboxylating) inhibitors
phosphogluconic acid dehydrogenase inhibitor
phosphogluconic acid dehydrogenase inhibitors
A role borne by a molecule that acts to counteract or neutralize the deleterious effects of paracetamol (acetaminophen).
A role borne by a molecule that acts to counteract or neutralize the deleterious effects of curare.
EC 2.3.2.2 (gamma-glutamyltransferase) inhibitor
(5-L-glutamyl)-peptide:amino-acid 5-glutamyltransferase inhibitor
(5-L-glutamyl)-peptide:amino-acid 5-glutamyltransferase inhibitors
An EC 2.3.2.* (aminoacyltransferase) inhibitor that interferes with the action of gamma-glutamyltransferase (EC 2.3.2.2).
EC 2.3.2.2 (gamma-glutamyltransferase) inhibitors
L-gamma-glutamyl transpeptidase inhibitor
L-gamma-glutamyl transpeptidase inhibitors
alpha-glutamyl transpeptidase inhibitors
gamma-glutamyl peptidyltransferase inhibitor
gamma-glutamyl peptidyltransferase inhibitors
gamma-glutamyl transpeptidase inhibitors
gamma-glutamyltransferase (EC 2.3.2.2) inhibitor
gamma-glutamyltransferase (EC 2.3.2.2) inhibitors
A compound that causes the contraction of body tissues, typically used to reduce bleeding from minor abrasions.
A compound used as a probe during microarray analysis of oligosaccharide-protein interactions.
A reagent used in the immobilization of compounds prior to their use in microarray analysis.
An EC 3.4.23.* (aspartic endopeptidase) inhibitor that interferes with the activity of memapsin 2 (EC 3.4.23.46).
beta-site APP-cleaving enzyme 1 inhibitor
beta-site APP-cleaving enzyme 1 inhibitors
beta-site Alzheimer's amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor
beta-site Alzheimer's amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors
beta-site Alzheimer's amyloid precursor protein cleaving enzyme 1 inhibitor
beta-site Alzheimer's amyloid precursor protein cleaving enzyme 1 inhibitors
membrane-associated aspartic protease 2 inhibitor
membrane-associated aspartic protease 2 inhibitors
An EC 3.1.27.* (endoribonucleases producing other than 5'-phosphomonoesters) inhibitor that interferes with the action of ribonuclease T1 (EC 3.1.27.3).
Aspergillus oryzae ribonuclease inhibitor
Aspergillus oryzae ribonuclease inhibitors
EC 3.1.27.3 (ribonuclease T1) inhibitors
ribonuclease T1 (EC 3.1.27.3) inhibitors
ribonuclease guaninenucleotido-2'-transferase (cyclising) inhibitor
ribonuclease guaninenucleotido-2'-transferase (cyclising) inhibitors
ribonuclease guaninenucleotido-2'-transferase (cyclizing) inhibitor
ribonuclease guaninenucleotido-2'-transferase (cyclizing) inhibitors
A serine/threonine kinase inhibitor that specifically inhibits human mutant serine/threonine kinase (B-Raf)
human mutant serine/threonine kinase inhibitor
human mutant serine/threonine kinase inhibitors
Colourless, endogenous or exogenous pigment precursors that may be transformed by biological mechanisms into coloured compounds. They are used in biochemical assays and in diagnosis as indicators, particularly in the form of enzyme substrates.
EC 2.5.1.21 (squalene synthase) inhibitor
An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of squalene synthase (EC 2.5.1.21).
EC 2.5.1.21 (squalene synthase) inhibitors
farnesyl-diphosphate farnesyltransferase inhibitor
farnesyl-diphosphate farnesyltransferase inhibitors
farnesyl-diphosphate:farnesyl-diphosphate farnesyltransferase inhibitor
farnesyl-diphosphate:farnesyl-diphosphate farnesyltransferase inhibitors
presqualene-diphosphate synthase inhibitor
presqualene-diphosphate synthase inhibitors
squalene synthase (EC 2.5.1.21) inhibitor
squalene synthase (EC 2.5.1.21) inhibitors
EC 5.4.3.2 (lysine 2,3-aminomutase) inhibitor
An EC 5.4.3.* (intramolecular transferase transferring amino groups) inhibitor that interferes with the action of lysine 2,3-aminomutase (EC 5.4.3.2).
EC 5.4.3.2 (lysine 2,3-aminomutase) inhibitors
lysine 2,3-aminomutase (EC 5.4.3.2) inhibitor
lysine 2,3-aminomutase (EC 5.4.3.2) inhibitors
insulin-like growth factor receptor 1 antagonist
An antagonist at the insulin-like growth factor receptor 1.
insulin-like growth factor receptor 1 antagonists
Any compound that inhibits one or more steps in the pathway leading to the synthesis of ergosterol.
Any substance that can induce the release of histamine from mast cells.
A generally pharmacologically inactive substance that is formulated with the active ingredient of a medication.
Any substance that accelerates defecation. Compare with laxatives, which are substances that ease defecation (usually by softening faeces). A substance can be both a laxative and a cathartic.
A chemical additive used to toughen or harden a polymer material by cross-linking of polymer chains.
An inhibitor of peroxidases (EC 1.11.1.*) that inhibits the action of catalase (EC 1.11.1.6).
hydrogen-peroxide:hydrogen-peroxide oxidoreductase inhibitor
hydrogen-peroxide:hydrogen-peroxide oxidoreductase inhibitors
An EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitor that interferes with the action of any of the peroxidases (EC 1.11.1.*).
platelet-activating factor receptor agonist
An agonist that binds to and activates platelet-activating factor receptors.
platelet-activating factor receptor agonists
EC 6.1.1.* (ligases forming aminoacyl tRNA and related compounds) inhibitor
An EC 6.1.* (C-O bond-forming ligase) inhibitor that interferes with the action of any ligase forming aminoacyl tRNA and related compounds (EC 6.1.1.*).
EC 6.1.1.* (ligases forming aminoacyl tRNA and related compounds) inhibitors
ligases forming aminoacyl tRNA and related compounds (EC 6.1.1.*) inhibitor
ligases forming aminoacyl tRNA and related compounds (EC 6.1.1.*) inhibitors
EC 1.4.4.2 [glycine dehydrogenase (aminomethyl-transferring)] inhibitor
An EC 1.4.4.* (oxidoreductase acting on donor CH-NH2 group, a disulfide as acceptor) inhibitor that interferes with the action of glycine decarboxylase (EC 1.4.4.2).
EC 1.4.4.2 (glycine dehydrogenase (aminomethyl-transferring)) inhibitor
EC 1.4.4.2 (glycine dehydrogenase (aminomethyl-transferring)) inhibitors
EC 1.4.4.2 [glycine dehydrogenase (aminomethyl-transferring)] inhibitors
glycine cleavage system P-protein inhibitor
glycine cleavage system P-protein inhibitors
glycine dehydrogenase (aminomethyl-transferring) (EC 1.4.4.2) inhibitor
glycine dehydrogenase (aminomethyl-transferring) (EC 1.4.4.2) inhibitors
glycine dehydrogenase (aminomethyl-transferring) inhibitor
glycine dehydrogenase (aminomethyl-transferring) inhibitors
glycine dehydrogenase (decarboxylating) inhibitor
glycine dehydrogenase (decarboxylating) inhibitors
glycine-cleavage complex P-protein inhibitor
glycine-cleavage complex P-protein inhibitors
glycine:H-protein-lipoyllysine oxidoreductase (decarboxylating, acceptor-amino-methylating)
glycine:H-protein-lipoyllysine oxidoreductase (decarboxylating, acceptor-amino-methylating) inhibitor
glycine:lipoylprotein oxidoreductase (decarboxylating and acceptor-aminomethylating) inhibitor
glycine:lipoylprotein oxidoreductase (decarboxylating and acceptor-aminomethylating) inhibitors
EC 6.1.1.11 (serine--tRNA ligase) inhibitor
An EC 6.1.1.* (ligases forming aminoacyl tRNA and related compounds) inhibitor that specifically inhibits the action of seryl-tRNA synthetase (EC 6.1.1.11).
EC 6.1.1.11 (serine--tRNA ligase) inhibitors
L-serine:tRNA(Ser) ligase (AMP-forming) inhibitor
L-serine:tRNA(Ser) ligase (AMP-forming) inhibitors
serine--tRNA ligase (EC 6.1.1.11) inhibitor
serine--tRNA ligase (EC 6.1.1.11) inhibitors
seryl-transfer RNA synthetase inhibitors
seryl-transfer ribonucleate synthetase inhibitor
seryl-transfer ribonucleate synthetase inhibitors
seryl-transfer ribonucleic acid synthetase inhibitor
seryl-transfer ribonucleic acid synthetase inhibitors
An EC 5.1.1.* (racemases acting on amino acids and derivatives) inhibitor that interferes with the action of alanine racemase (EC 5.1.1.1).
EC 5.1.1.1 (alanine racemase) inhibitors
alanine racemase (EC 5.1.1.1) inhibitors
An enzyme inhibitor that inhibits the action of an isomerase (EC 5.*.*.*).
EC 6.3.2.4 (D-alanine--D-alanine ligase) inhibitor
An acid--amino-acid ligase inhibitor that inhibits the action of a D-alanine--D-alanine ligase (EC 6.3.2.4).
D-alanine--D-alanine ligase (EC 6.3.2.4) inhibitor
D-alanine--D-alanine ligase (EC 6.3.2.4) inhibitors
D-alanine:D-alanine ligase (ADP-forming) inhibitor
D-alanine:D-alanine ligase (ADP-forming) inhibitors
EC 6.3.2.4 (D-alanine--D-alanine ligase) inhibitors
alanine:alanine ligase (ADP-forming) inhibitor
alanine:alanine ligase (ADP-forming) inhibitors
EC 6.3.2.2 (glutamate--cysteine ligase) inhibitor
An acid--amino-acid ligase inhibitor that inhibits the action of a glutamate--cysteine ligase (EC 6.3.2.2)
EC 6.3.2.2 (glutamate--cysteine ligase) inhibitors
gamma-glutamyl-L-cysteine synthetase inhibitor
gamma-glutamyl-L-cysteine synthetase inhibitors
gamma-glutamylcysteine synthetase inhibitor
gamma-glutamylcysteine synthetase inhibitors
gamma-glutamylcysteinyl synthetase inhibitor
gamma-glutamylcysteinyl synthetase inhibitors
glutamate--cysteine ligase (EC 6.3.2.2) inhibitor
glutamate--cysteine ligase (EC 6.3.2.2) inhibitors
EC 6.3.* (C-N bond-forming ligase) inhibitor
A ligase inhibitor that interferes with the action of a C-N bond-forming ligase (EC 6.3.*.*).
C-N bond-forming ligase (EC 6.3.*) inhibitor
C-N bond-forming ligase (EC 6.3.*) inhibitors
EC 6.3.* (C-N bond-forming ligase) inhibitorS
Any enzyme inhibitor that interferes with the action of a ligase (EC 6.*.*.*). Ligases are enzymes that catalyse the joining of two molecules with concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
EC 6.4.* (C-C bond-forming ligase) inhibitor
A ligase inhibitor that interferes with the action of a C-C bond-forming ligase (EC 6.4.*.*).
C-C bond-forming ligase (EC 6.4.*) inhibitor
C-C bond-forming ligase (EC 6.4.*) inhibitorS
EC 6.4.* (C-C bond-forming ligase) inhibitorS
EC 6.5.* (phosphoric ester bond-forming ligase) inhibitor
A ligase inhibitor which inhibits the action of a phosphoric ester bond-forming ligase (EC 6.5.*.*).
EC 6.5.* (phosphoric ester bond-forming ligase) inhibitors
phosphoric ester bond-forming ligase (EC 6.5.*) inhibitor
phosphoric ester bond-forming ligase (EC 6.5.*) inhibitors
phosphoric ester bond-forming ligase inhibitor
phosphoric ester bond-forming ligase inhibitors
dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Any metabolite produced during a metabolic reaction in eukaryotes, the taxon that include members of the fungi, plantae and animalia kingdoms.
Any eukaryotic metabolite produced during a metabolic reaction in animals that include diverse creatures from sponges, insects to mammals.
Any animal metabolite produced during a metabolic reaction in mammals.
Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae).
Saccharomyces cerevisiae secondary metabolites
Any metabolite produced during a metabolic reaction in prokaryotes, the taxon that include members of domains such as the bacteria and archaea.
A compound which increases either the number of red cells or the amount of haemoglobin in the blood.
EC 6.3.2.19 (ubiquitin--protein ligase) inhibitor
An enzyme inhibitor that interferes with the action of ubiquitin--protein ligase (EC 6.3.2.19).
EC 6.3.2.19 (ubiquitin--protein ligase) inhibitors
S-phase kinase-associated protein 2 inhibitor
S-phase kinase-associated protein 2 inhibitors
ubiquitin:protein-lysine N-ligase (AMP-forming) inhibitor
ubiquitin:protein-lysine N-ligase (AMP-forming) inhibitors
Any compound that binds to and activates soluble guanylate cyclase (EC 4.6.1.2).
Any metabolite produced by metabolism of a xenobiotic compound.
A non-fluorescent small compound which become fluorescent only when complexed to a fluorogen activating protein (FAP).
EC 2.3.1.48 (histone acetyltransferase) inhibitor
An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the function of histone acetyltransferase (EC 2.3.1.48).
EC 2.3.1.48 (histone acetyltransferase) inhibitors
acetyl-CoA:histone acetyltransferase inhibitor
acetyl-CoA:histone acetyltransferase inhibitors
histone acetyltransferase (EC 2.3.1.48) inhibitor
histone acetyltransferase (EC 2.3.1.48) inhibitors
nucleosome-histone acetyltransferase inhibitor
nucleosome-histone acetyltransferase inhibitors
A gas in an atmosphere that absorbs and emits radiation within the thermal infrared range, so contributing to the 'greenhouse effect'.
A compressed gas or liquid with a boiling point lower than room temperature which to used to propel and dispense liquids such as deodorants, insecticides, paints, etc. from aerosol cans.
Any animal metabolite produced during a metabolic reaction in corals (marine invertebrates).
Any metabolite produced during a metabolic reaction in marine macro- and microorganisms.
Any protective agent that is able to prevent damage to the kidney.
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor
ATP:[protein]-L-tyrosine O-phosphotransferase (non-specific) inhibitor
ATP:[protein]-L-tyrosine O-phosphotransferase (non-specific) inhibitors
An EC 2.7.10.* (protein-tyrosine kinase) inhibitor that specifically blocks the action of non-specific protein-tyrosine kinase (EC 2.7.10.2).
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitors
cytoplasmic protein tyrosine kinase inhibitor
cytoplasmic protein tyrosine kinase inhibitors
non-specific protein-tyrosine kinase (EC 2.7.10.2) inhibitor
non-specific protein-tyrosine kinase (EC 2.7.10.2) inhibitors
p60c-src protein tyrosine kinase inhibitor
p60c-src protein tyrosine kinase inhibitors
A compound used to return an excited fluorophore to the ground state by transfer of energy from fluorophore to quencher without the emission of light, with the quencher being promoted to its own excited state.
A transferase inhibitor inhibiting the action of transferase of a one-carbon-containing group (EC 2.1.*.*).
one-carbon-containing group transferase inhibitor
one-carbon-containing group transferase inhibitors
EC 2.2.* (aldehyde or ketone transferase) inhibitor
A transferase inhibitor interfering with the action of any transferase that transfers an aldehyde or ketone group (EC 2.2.*.*).
EC 2.2.* (aldehyde or ketone transferase) inhibitors
aldehyde or ketone transferase inhibitor
aldehyde or ketone transferase inhibitors
aldehyde/ketone transferase (EC 2.2.*) inhibitor
aldehyde/ketone transferase (EC 2.2.*) inhibitors
A transferase inhibitor that interferes with the action of an acyltransferase (EC 2.3.*.*).
EC 2.4.* (glycosyltransferase) inhibitor
A transferase inhibitor inhibiting the action of a glycosyltransferase (EC 2.4.*.*).
EC 2.4.* (glycosyltransferase) inhibitors
glycosyltransferase (EC 2.4.*) inhibitor
glycosyltransferase (EC 2.4.*) inhibitors
EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor
A transferase inhibitor that inhibits the transfer of an alkyl (other than methyl) or aryl group (EC 2.5.1.*).
EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitors
alkyl/aryl (non-methyl) transferase inhibitor
alkyl/aryl (non-methyl) transferase inhibitors
non-methyl alkyl/aryl transferase (EC 2.5.1.*) inhibitor
non-methyl alkyl/aryl transferase (EC 2.5.1.*) inhibitors
non-methyl alkyl/aryl transferase inhibitor
non-methyl alkyl/aryl transferase inhibitors
non-methyl-alkyl or aryl transferase inhibitor
non-methyl-alkyl or aryl transferase inhibitors
EC 2.6.* (nitrogenous group transferase) inhibitor
A transferase inhibitor that inhibits a nitrogenous group transferase (EC 2.6.*.*).
nitrogenous group transferase (EC 2.6.*) inhibitor
nitrogenous group transferase (EC 2.6.*) inhibitors
nitrogenous group transferase inhibitors
EC 2.7.* (P-containing group transferase) inhibitor
A transferase inhibitor that inhibits the action of a phosphorus-containing group transferase (EC 2.7.*.*).
EC 2.7.* (P-containing group transferase) inhibitors
EC 2.7.* (phosphorus-containing group transferase) inhibitor
EC 2.7.* (phosphorus-containing group transferase) inhibitors
phosphorus-containing group transferase (EC 2.7.*) inhibitor
phosphorus-containing group transferase (EC 2.7.*) inhibitors
phosphorus-containing group transferase inhibitor
phosphorus-containing group transferase inhibitors
EC 2.8.* (S-containing group transferase) inhibitor
A transferase inhibitor that interferes with the action of a sulfur-containing group transferase (EC 2.8.*.*).
EC 2.8.* (S-containing group transferase) inhibitors
S-containing group transferase inhibitor
S-containing group transferase inhibitors
sulfur-containing group transferase (EC 2.8.*) inhibitor
sulfur-containing group transferase (EC 2.8.*) inhibitors
sulfur-containing group transferase inhibitor
sulfur-containing group transferase inhibitors
EC 2.9.* (Se-containing group transferase) inhibitor
A transferase inhibitor that interferes with the action of a selenium-containing group transferase (EC 2.9.*.*).
EC 2.9.* (Se-containing group transferase) inhibitors
Se-containing group transferase inhibitor
Se-containing group transferase inhibitors
selenium-containing group transferase (EC 2.9.*) inhibitor
selenium-containing group transferase (EC 2.9.*) inhibitors
selenium-containing group transferase inhibitor
selenium-containing group transferase inhibitors
EC 2.10.* (Mo- or W-containing group transferase) inhibitor
A transferase inhibitor that interferes with the action of a molybdenum- or tungsten-containing group transferase (EC 2.10.*.*).
EC 2.10.* (Mo- or W-containing group transferase) inhibitors
Mo- or W-containing group transferase (EC 2.10.*) inhibitor
Mo- or W-containing group transferase (EC 2.10.*) inhibitors
Mo- or W-containing group transferase inhibitor
Mo- or W-containing group transferase inhibitors
An isomerase inhibitor interfering with the action of a racemase or epimerase (EC 5.1.*.*).
EC 5.1.* (racemase/epimerase) inhibitors
racemase and epimerase (EC 5.1*) inhibitor
racemase and epimerase (EC 5.1*) inhibitors
EC 5.2.* (cis-trans-isomerase) inhibitor
An isomerase inhibitor interfering with the action of a cis-trans-isomerase (EC 5.2.*.*).
EC 5.2.* (cis-trans-isomerase) inhibitors
cis-trans-isomerase (EC5.2.*) inhibitors
EC 5.3.* (intramolecular oxidoreductase) inhibitor
An isomerase inhibitor that interferes with the action of an intramolecular oxidoreductase (EC 5.3.*.*).
EC 5.3.* (intramolecular oxidoreductase) inhibitors
intramolecular oxidoreductase (EC 5.3.*) inhibitor
intramolecular oxidoreductase (EC 5.3.*) inhibitors
intramolecular oxidoreductase inhibitors
EC 5.4.* (intramolecular transferase) inhibitor
An isomerase inhibitor that interferes with the action of an intramolecular transferase (EC 5.4.*.*).
EC 5.4.* (intramolecular transferase) inhibitors
intramolecular transferase (EC 5.4.*) inhibitor
intramolecular transferase (EC 5.4.*) inhibitors
EC 5.5.* (intramolecular lyase) inhibitor
An isomerase inhibitor that interferes with the action of an intramolecular lyase (EC 5.5.*.*).
EC 5.5.* (intramolecular lyase) inhibitors
An isomerase inhibitor that interferes with the action of any member of the group of 'other isomerases' (EC 5.99.*.*).
EC 5.99.* (miscellaneous isomerases) inhibitor
EC 5.99.* (miscellaneous isomerases) inhibitors
EC 6.1.* (C-O bond-forming ligase) inhibitor
A ligase inhibitor that interferes with the action of a C-O bond-forming ligase (EC 6.1.*.*).
C-O bond-forming ligase (EC 6.1.*) inhibitor
C-O bond-forming ligase (EC 6.1.*) inhibitors
EC 6.1.* (C-O bond-forming ligase) inhibitors
EC 6.2.* (C-S bond-forming ligase) inhibitor
A ligase inhibitor that interferes with the action of a C-S bond-forming ligase (EC 6.2.*.*).
C-S bond-forming ligase (EC 6.2.*) inhibitor
C-S bond-forming ligase (EC 6.2.*) inhibitors
EC 6.2.* (C-S bond-forming ligase) inhibitors
EC 6.6.* (N-metal bond-forming ligase) inhibitor
A ligase inhibitor which interferes with the action of a nitrogen-metal bond-forming ligase (EC 6.6.*.*).
EC 6.6.* (N-metal bond-forming ligase) inhibitors
N-metal bond-forming ligase (EC 6.6.*) inhibitor
N-metal bond-forming ligase (EC 6.6.*) inhibitors
An enzyme inhibitor which interferes with the action of a lyase (EC 4.*.*.*). Lyases are enzymes cleaving C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation.
A lyase inhibitor which inhibits the action of a C-C lyase (EC 4.1.*.*).
A lyase inhibitor which inhibits the action of a C-O lyase (EC 4.2.*.*).
A lyase inhibitor which inhibits the action of a C-N lyase (EC 4.3.*.*).
A lyase inhibitor which inhibits the action of a C-S lyase (EC 4.4.*.*).
A lyase inhibitor which inhibits the action of a C-halide lyase (EC 4.5.*.*).
A lyase inhibitor which inhibits the action of a P-O lyase (EC 4.6.*.*).
A lyase inhibitor which inhibits the action of a C-P lyase (EC 4.6.*.*).
EC 4.99.* (miscellaneous lyase) inhibitor
A lyase inhibitor which interferes with the activity of a lyase in the EC 4.99.*.* group.
EC 4.99.* (miscellaneous lyase) inhibitors
miscellaneous lyase (EC 4.99.*) inhibitor
miscellaneous lyase (EC 4.99.*) inhibitors
A synthetic oligonucleotide whose base sequence is complementary to a gene's messenger RNA (mRNA) and which will bind with the mRNA inactivating it.
An enzyme inhibitor which interferes with the action of an oxidoreductase (EC 1.*.*.*).
EC 1.1.* (oxidoreductase acting on donor CH-OH group) inhibitor
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the CH-OH group of donors (EC 1.1.*.*).
EC 1.1.* (oxidoreductase acting on donor CH-OH group) inhibitors
inhibitor of oxidoreductase acting on CH-OH group of donor
inhibitor of oxidoreductase acting on CH-OH group of donors
inhibitors of oxidoreductase acting on CH-OH group of donor
inhibitors of oxidoreductase acting on CH-OH group of donors
oxidoreductase acting on donor CH-OH group (EC 1.1.*) inhibitor
oxidoreductase acting on donor CH-OH group (EC 1.1.*) inhibitors
oxidoreductase acting on donor CH-OH group inhibitor
oxidoreductase acting on donor CH-OH group inhibitors
EC 1.2.* (oxidoreductase acting on donor aldehyde/oxo group) inhibitor
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the aldehyde or oxo group of donors (EC 1.2.*.*).
EC 1.2.* (oxidoreductase acting on donor aldehyde or oxo group) inhibitor
EC 1.2.* (oxidoreductase acting on donor aldehyde or oxo group) inhibitors
EC 1.2.* (oxidoreductase acting on donor aldehyde/oxo group) inhibitors
inhibitor of oxidoreductase acting on aldehyde or oxo group of donor
inhibitor of oxidoreductase acting on aldehyde or oxo group of donors
inhibitor of oxidoreductase acting on aldehyde/oxo group of donor
inhibitor of oxidoreductase acting on aldehyde/oxo group of donors
inhibitors of oxidoreductase acting on aldehyde or oxo group of donor
inhibitors of oxidoreductase acting on aldehyde or oxo group of donors
inhibitors of oxidoreductase acting on aldehyde/oxo group of donor
inhibitors of oxidoreductase acting on aldehyde/oxo group of donors
oxidoreductase acting on donor aldehyde or oxo group (EC 1.2.*) inhibitor
oxidoreductase acting on donor aldehyde or oxo group (EC 1.2.*) inhibitors
oxidoreductase acting on donor aldehyde or oxo group inhibitor
oxidoreductase acting on donor aldehyde or oxo group inhibitors
oxidoreductase acting on donor aldehyde/oxo group (EC 1.2.*) inhibitor
oxidoreductase acting on donor aldehyde/oxo group (EC 1.2.*) inhibitors
oxidoreductase acting on donor aldehyde/oxo group inhibitor
oxidoreductase acting on donor aldehyde/oxo group inhibitors
EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the CH-CH group of donors (EC 1.3.*.*).
EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitors
inhibitor of oxidoreductase acting on CH-CH group of donor
inhibitor of oxidoreductase acting on CH-CH group of donors
inhibitors of oxidoreductase acting on CH-CH group of donor
inhibitors of oxidoreductase acting on CH-CH group of donors
oxidoreductase acting on donor CH-CH group (EC 1.3.*) inhibitor
oxidoreductase acting on donor CH-CH group (EC 1.3.*) inhibitors
oxidoreductase acting on donor CH-CH group inhibitor
oxidoreductase acting on donor CH-CH group inhibitors
EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the CH-NH2 group of donors (EC 1.4.*.*).
EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitors
inhibitor of oxidoreductase acting on CH-NH2 group of donor
inhibitor of oxidoreductase acting on CH-NH2 group of donors
inhibitors of oxidoreductase acting on CH-NH2 group of donor
inhibitors of oxidoreductase acting on CH-NH2 group of donors
oxidoreductase acting on CH-NH2 group of donor inhibitor
oxidoreductase acting on CH-NH2 group of donor inhibitors
oxidoreductase acting on CH-NH2 group of donors (EC 1.4.*) inhibitor
oxidoreductase acting on CH-NH2 group of donors (EC 1.4.*) inhibitors
EC 1.5.* (oxidoreductase acting on donor CH-NH group) inhibitor
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the CH-NH group of donors (EC 1.5.*.*).
EC 1.5.* (oxidoreductase acting on donor CH-NH group) inhibitors
inhibitor of oxidoreductase acting on CH-NH group of donor
inhibitor of oxidoreductase acting on CH-NH group of donors
inhibitors of oxidoreductase acting on CH-NH group of donor
inhibitors of oxidoreductase acting on CH-NH group of donors
oxidoreductase acting on donor CH-NH group (EC 1.5.*) inhibitor
oxidoreductase acting on donor CH-NH group (EC 1.5.*) inhibitors
EC 1.6.* (oxidoreductase acting on NADH or NADPH) inhibitor
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on NADH or NADPH (EC 1.6.*.*).
EC 1.6.* (oxidoreductase acting on NADH or NADPH) inhibitors
inhibitor of oxidoreductase acting on NADH or NADPH
inhibitor of oxidoreductase acting on NADH or NADPH (EC 1.6.*)
inhibitors of oxidoreductase acting on NADH or NADPH
inhibitors of oxidoreductase acting on NADH or NADPH (EC 1.6.*)
oxidoreductase acting on NADH or NADPH (EC 1.6.*) inhibitor
oxidoreductase acting on NADH or NADPH (EC 1.6.*) inhibitors
oxidoreductase acting on NADH or NADPH inhibitor
oxidoreductase acting on NADH or NADPH inhibitors
EC 1.7.* (oxidoreductase acting on other nitrogenous compounds as donors) inhibitor
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase of class EC 1.7.*.* (acting on other nitrogenous compounds as donors).
EC 1.7.* (oxidoreductase acting on other nitrogenous compounds as donors) inhibitors
inhibitor of oxidoreductase acting on other nitrogenous compounds as donors
inhibitor of oxidoreductase acting on other nitrogenous compounds as donors (EC 1.7.*)
inhibitors of oxidoreductase acting on other nitrogenous compounds as donors
inhibitors of oxidoreductase acting on other nitrogenous compounds as donors (EC 1.7.*)
EC 1.8.* (oxidoreductase acting on sulfur group of donors) inhibitor
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase of class EC 1.8.*.* (acting on a sulfur group of donors).
EC 1.8.* (oxidoreductase acting on sulfur group of donors) inhibitors
oxidoreductase acting on a sulfur group of donors (EC 1.8.*) inhibitor
oxidoreductase acting on a sulfur group of donors (EC 1.8.*) inhibitors
EC 1.9.* (oxidoreductase acting on donor heme group) inhibitor
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on a heme group of donors (EC 1.9.*.*).
EC 1.9.* (oxidoreductase acting on a heme group of donors) inhibitor
EC 1.9.* (oxidoreductase acting on a heme group of donors) inhibitors
EC 1.9.* (oxidoreductase acting on donor heme group) inhibitors
oxidoreductase acting on a heme group of donors (EC 1.9.*) inhibitor
oxidoreductase acting on a heme group of donors (EC 1.9.*) inhibitors
EC 1.10.* (oxidoreductase acting on diphenols and related substances as donors) inhibitor
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on diphenols and related substances as donors (EC 1.10.*.*).
EC 1.10.* (oxidoreductase acting on diphenols and related substances as donors) inhibitors
EC 1.10.* (oxidoreductases acting on diphenols and related substances as donors) inhibitor
EC 1.10.* (oxidoreductases acting on diphenols and related substances as donors) inhibitors
inhibitor of an oxidoreductase acting on diphenols and related substances as donor
inhibitor of an oxidoreductase acting on diphenols and related substances as donor (EC 1.10.*)
inhibitor of an oxidoreductase acting on diphenols and related substances as donors
inhibitors of an oxidoreductase acting on diphenols and related substances as donor
inhibitors of an oxidoreductase acting on diphenols and related substances as donor (EC 1.10.*)
inhibitors of an oxidoreductase acting on diphenols and related substances as donors
EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitor
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on peroxide as donors (EC 1.11.*.*).
EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitors
EC 1.11.* (oxidoreductases acting on peroxide as donors) inhibitor
EC 1.11.* (oxidoreductases acting on peroxide as donors) inhibitors
oxidoreductase acting on peroxide as donors (EC 1.11.*) inhibitor
oxidoreductase acting on peroxide as donors (EC 1.11.*) inhibitors
oxidoreductases acting on peroxide as donors (EC 1.11.*) inhibitor
oxidoreductases acting on peroxide as donors (EC 1.11.*) inhibitors
EC 1.12.* (oxidoreductase acting on hydrogen as donors) inhibitor
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on hydrogen as donors (EC 1.12.*.*).
EC 1.12.* (oxidoreductase acting on hydrogen as donors) inhibitors
EC 1.12.* (oxidoreductases acting on hydrogen as donors) inhibitor
EC 1.12.* (oxidoreductases acting on hydrogen as donors) inhibitors
inhibitor of oxidoreductase acting on hydrogen as donors
inhibitor of oxidoreductase acting on hydrogen as donors (EC 1.12.*)
inhibitors of oxidoreductase acting on hydrogen as donors
inhibitors of oxidoreductase acting on hydrogen as donors (EC 1.12.*)
oxidoreductase acting on hydrogen as donors inhibitor
oxidoreductase acting on hydrogen as donors inhibitors
EC 1.13.* [oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases)] inhibitor
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases), EC 1.13.*.*.
EC 1.13.* [oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases)] inhibitors
oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases) (EC 1.13.*) inhibitor
oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases) (EC 1.13.*) inhibitors
oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases) inhibitor
oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases) inhibitors
EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on hydrogen as donors (EC 1.14.*.*).
EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitors
inhibitor of oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*)
inhibitor of oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*)
inhibitors of oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*)
inhibitors of oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*)
oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*) inhibitor
oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*) inhibitors
oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen inhibitor
oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen inhibitors
EC 1.15.* (oxidoreductase acting on superoxide as acceptor) inhibitor
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on superoxide as acceptor (EC 1.15.*.*).
EC 1.15.* (oxidoreductase acting on superoxide as acceptor) inhibitors
inhibitor of oxidoreductase acting on superoxide as acceptor
inhibitor of oxidoreductase acting on superoxide as acceptor (EC 1.15.*)
inhibitors of oxidoreductase acting on superoxide as acceptor
inhibitors of oxidoreductase acting on superoxide as acceptor (EC 1.15.*)
oxidoreductase acting on superoxide as acceptor (EC 1.15.*) inhibitor
oxidoreductase acting on superoxide as acceptor (EC 1.15.*) inhibitors
oxidoreductase acting on superoxide as acceptor inhibitor
oxidoreductase acting on superoxide as acceptor inhibitors
EC 1.16.* (oxidoreductase oxidising metal ions) inhibitor
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase oxidising metal ions (EC 1.16.*.*).
EC 1.16.* (oxidoreductase oxidising metal ions) inhibitors
EC 1.16.* (oxidoreductase oxidizing metal ions) inhibitor
EC 1.16.* (oxidoreductase oxidizing metal ions) inhibitors
oxidoreductase oxidising metal ions (EC 1.16.*) inhibitor
oxidoreductase oxidising metal ions (EC 1.16.*) inhibitors
oxidoreductase oxidising metal ions inhibitor
oxidoreductase oxidising metal ions inhibitors
oxidoreductase oxidizing metal ions (EC 1.16.*) inhibitor
oxidoreductase oxidizing metal ions (EC 1.16.*) inhibitors
oxidoreductase oxidizing metal ions inhibitor
oxidoreductase oxidizing metal ions inhibitors
EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitor
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on CH or CH2 (EC 1.17.*.*).
EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitors
oxidoreductase acting on CH or CH2 (EC 1.17.*) inhibitor
oxidoreductase acting on CH or CH2 (EC 1.17.*) inhibitors
oxidoreductase acting on CH or CH2 inhibitor
oxidoreductase acting on CH or CH2 inhibitors
EC 1.18.* (oxidoreductase acting on Fe-S proteins as donors) inhibitor
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on iron-sulfur proteins as donors (EC 1.18.*.*).
EC 1.18.* (oxidoreductase acting on Fe-S proteins as donors) inhibitors
EC 1.18.* (oxidoreductase acting on iron-sulfur proteins as donors) inhibitor
EC 1.18.* (oxidoreductase acting on iron-sulfur proteins as donors) inhibitors
inhibitor of oxidoreductase acting on Fe-S proteins as donors
inhibitor of oxidoreductase acting on iron-sulfur proteins as donors
inhibitors of oxidoreductase acting on Fe-S proteins as donors
inhibitors of oxidoreductase acting on iron-sulfur proteins as donors
inhibitors of oxidoreductases acting on iron-sulfur proteins as donors
oxidoreductase acting on Fe-S proteins as donors (EC 1.18.*) inhibitor
oxidoreductase acting on Fe-S proteins as donors (EC 1.18.*) inhibitors
oxidoreductase acting on iron-sulfur proteins as donors (EC 1.18.*) inhibitor
oxidoreductase acting on iron-sulfur proteins as donors (EC 1.18.*) inhibitors
EC 1.19.* (oxidoreductase acting on reduced flavodoxin as donor) inhibitor
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on reduced flavodoxin as donor (EC 1.19.*.*).
EC 1.19.* (oxidoreductase acting on reduced flavodoxin as donor) inhibitors
inhibitor of oxidoreductase acting on reduced flavodoxin as donor
inhibitor of oxidoreductase acting on reduced flavodoxin as donor (EC 1.19.*)
inhibitors of oxidoreductase acting on reduced flavodoxin as donor
inhibitors of oxidoreductase acting on reduced flavodoxin as donor (EC 1.19.*)
oxidoreductase acting on reduced flavodoxin as donor (EC 1.19.*) inhibitor
oxidoreductase acting on reduced flavodoxin as donor (EC 1.19.*) inhibitors
EC 1.20.* (oxidoreductase acting on P or As in donors) inhibitor
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on phosphorus or arsenic in donors (EC 1.20.*.*).
EC 1.20.* (oxidoreductase acting on P or As in donors) inhibitors
EC 1.20.* (oxidoreductase acting on phosphorus or arsenic in donors) inhibitor
EC 1.20.* (oxidoreductase acting on phosphorus or arsenic in donors) inhibitors
oxidoreductase acting on P or As in donors (EC 1.20.*) inhibitor
oxidoreductase acting on P or As in donors (EC 1.20.*) inhibitors
oxidoreductase acting on phosphorus or arsenic in donors (EC 1.20.*) inhibitor
oxidoreductase acting on phosphorus or arsenic in donors (EC 1.20.*) inhibitors
EC 1.21.* (oxidoreductase acting on X-H and Y-H to form an X-Y bond) inhibitor
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on X-H and Y-H to form an X-Y bond (EC 1.21.*.*).
EC 1.21.* (oxidoreductase acting on X-H and Y-H to form an X-Y bond) inhibitors
oxidoreductase acting on X-H and Y-H to form an X-Y bond (EC 1.21.*) inhibitor
oxidoreductase acting on X-H and Y-H to form an X-Y bond (EC 1.21.*) inhibitors
oxidoreductase acting on X-H and Y-H to form an X-Y bond inhibitor
oxidoreductase acting on X-H and Y-H to form an X-Y bond inhibitors
EC 1.22.* (oxidoreductase acting on halogen in donors) inhibitor
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on halogen in donors (EC 1.22.*.*).
EC 1.22.* (oxidoreductase acting on halogen in donors) inhibitors
inhibitor of oxidoreductase acting on halogen in donors
inhibitor of oxidoreductase acting on halogen in donors (EC 1.22.*)
inhibitors of oxidoreductase acting on halogen in donors
inhibitors of oxidoreductase acting on halogen in donors (EC 1.22.*)
oxidoreductase acting on halogen in donors (EC 1.22.*) inhibitor
oxidoreductase acting on halogen in donors (EC 1.22.*) inhibitors
EC 1.23.* (oxidoreductase acting on C-O-C group as acceptor) inhibitor
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on C-O-C group as acceptor (EC 1.23.*.*).
EC 1.23.* (oxidoreductase acting on C-O-C group as acceptor) inhibitors
inhibitor of oxidoreductase acting on C-O-C group as acceptor
inhibitor of oxidoreductase acting on C-O-C group as acceptor (EC 1.23.*)
inhibitors of oxidoreductase acting on C-O-C group as acceptor
inhibitors of oxidoreductase acting on C-O-C group as acceptor (EC 1.23.*)
oxidoreductase acting on C-O-C group as acceptor (EC 1.23.*) inhibitor
oxidoreductase acting on C-O-C group as acceptor (EC 1.23.*) inhibitors
oxidoreductase acting on C-O-C group as acceptor inhibitor
oxidoreductase acting on C-O-C group as acceptor inhibitors
EC 1.97.* (other oxidoreductase) inhibitor
An oxidoreductase inhibitor which interferes with the action of any oxidoreductase that is classified as EC 1.97.*.*, (those oxidoreductases not included in any other EC 1.* category).
EC 1.97.* (miscellaneous oxidoreductase) inhibitor
EC 1.97.* (miscellaneous oxidoreductase) inhibitors
EC 1.97.* (other oxidoreductase) inhibitors
inhibitor of 'other' oxidoreductase (EC 1.97.*)
inhibitor of miscellaneous oxidoreductase (EC 1.97.*)
inhibitors of 'other' oxidoreductase (EC 1.97.*)
inhibitors of miscellaneous oxidoreductase (EC 1.97.*)
EC 1.98.* (enzymes using H2 as reductant) inhibitor
An oxidoreductase inhibitor which interferes with the action of any oxidoreductase using H2 as reductant (EC 1.98.*.*).
EC 1.98.* (enzymes using H2 as reductant) inhibitors
inhibitor of enzymes using H2 as reductant (EC 1.98.*)
inhibitors of enzymes using H2 as reductant (EC 1.98.*)
EC 1.99.* (other oxidoreductases using O2 as oxidant) inhibitor
An oxidoreductase inhibitor which interferes with the action of any oxidoreductase that is classified as EC 1.99.*.* (other oxidoreductases using O2 as oxidant).
EC 1.99.* (other oxidoreductases using O2 as oxidant) inhibitors
Any enzyme inhibitor that interferes with the action of a hydrolase (EC 3.*.*.*).
A hydrolase inhibitor that interferes with the action of any ester hydrolase (EC 3.1.*.*).
A hydrolase inhibitor that interferes with the action of any glycosylase (EC 3.2.*.*).
A hydrolase inhibitor that interferes with the action of any hydrolase acting on an ether bond (EC 3.3.*.*).
EC 3.3.* (hydrolase acting on ether bond) inhibitor
EC 3.3.* (hydrolase acting on ether bond) inhibitors
EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor
Any hydrolase inhibitor that interferes with the action of a hydrolase acting on C-N bonds, other than peptide bonds (EC 3.5.*.*).
EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitor
EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitors
EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitor
EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitors
EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitors
EC 3.7.* (hydrolases acting on C-C bonds) inhibitor
Any hydrolase inhibitor that interferes with the action of a hydrolase acting on carbon-carbon bonds (EC 3.7.*.*).
EC 3.7.* (hydrolases acting on C-C bonds) inhibitors
EC 3.7.* (hydrolases acting on carbon-carbon bonds) inhibitor
EC 3.7.* (hydrolases acting on carbon-carbon bonds) inhibitors
EC 3.8.* (hydrolases acting on halide bonds) inhibitor
Any hydrolase inhibitor that interferes with the action of a hydrolase acting on halide bonds (EC 3.8.*.*).
EC 3.8.* (hydrolases acting on halide bonds) inhibitors
hydrolases acting on halide bonds (EC 3.8.*) inhibitor
hydrolases acting on halide bonds (EC 3.8.*) inhibitors
inhibitor of hydrolases acting on halide bonds (EC 3.8.*)
inhibitors of hydrolases acting on halide bonds (EC 3.8.*)
EC 3.9.* (hydrolases acting on P-N bonds) inhibitor
Any hydrolase inhibitor that interferes with the action of a hydrolase acting on phosphorus-nitrogen bonds (EC 3.9.*.*).
EC 3.9.* (hydrolases acting on P-N bonds) inhibitors
EC 3.9.* (hydrolases acting on phosphorus-nitrogen bonds) inhibitor
EC 3.9.* (hydrolases acting on phosphorus-nitrogen bonds) inhibitors
hydrolases acting on P-N bonds (EC 3.9.*) inhibitor
hydrolases acting on P-N bonds (EC 3.9.*) inhibitors
hydrolases acting on phosphorus-nitrogen bonds (EC 3.9.*) inhibitor
hydrolases acting on phosphorus-nitrogen bonds (EC 3.9.*) inhibitors
inhibitor of hydrolases acting on P-N bonds
inhibitor of hydrolases acting on P-N bonds (EC 3.9.*)
inhibitor of hydrolases acting on phosphorus-nitrogen bonds
inhibitor of hydrolases acting on phosphorus-nitrogen bonds (EC 3.9.*)
inhibitors of hydrolases acting on P-N bonds
inhibitors of hydrolases acting on P-N bonds (EC 3.9.*)
inhibitors of hydrolases acting on phosphorus-nitrogen bonds
inhibitors of hydrolases acting on phosphorus-nitrogen bonds (EC 3.9.*)
EC 3.10.* (hydrolases acting on S-N bonds) inhibitor
Any hydrolase inhibitor that interferes with the action of a hydrolase acting on sulfur-nitrogen bonds (EC 3.10.*.*).
EC 3.10.* (hydrolases acting on S-N bonds) inhibitors
EC 3.10.* (hydrolases acting on sulfur-nitrogen bonds) inhibitor
EC 3.10.* (hydrolases acting on sulfur-nitrogen bonds) inhibitors
hydrolases acting on S-N bonds (EC 3.10.*) inhibitor
hydrolases acting on S-N bonds (EC 3.10.*) inhibitors
hydrolases acting on sulfur-nitrogen bonds (EC 3.10.*) inhibitor
hydrolases acting on sulfur-nitrogen bonds (EC 3.10.*) inhibitors
inhibitor of hydrolases acting on S-N bonds
inhibitor of hydrolases acting on S-N bonds (EC 3.10.*)
inhibitor of hydrolases acting on sulfur-nitrogen bonds
inhibitor of hydrolases acting on sulfur-nitrogen bonds (EC 3.10.*)
inhibitors of hydrolases acting on S-N bonds
inhibitors of hydrolases acting on S-N bonds (EC 3.10.*)
inhibitors of hydrolases acting on sulfur-nitrogen bonds
inhibitors of hydrolases acting on sulfur-nitrogen bonds (EC 3.10.*)
EC 3.11.* (hydrolases acting on C-P bonds) inhibitor
Any hydrolase inhibitor that interferes with the action of a hydrolase acting on carbon-phosphorus bonds (EC 3.11.*.*).
EC 3.11.* (hydrolases acting on C-P bonds) inhibitors
EC 3.11.* (hydrolases acting on carbon-phosphorus bonds) inhibitor
EC 3.11.* (hydrolases acting on carbon-phosphorus bonds) inhibitors
hydrolases acting on C-P bonds (EC 3.11.*) inhibitor
hydrolases acting on C-P bonds (EC 3.11.*) inhibitors
hydrolases acting on carbon-phosphorus bonds (EC 3.11.*) inhibitor
hydrolases acting on carbon-phosphorus bonds (EC 3.11.*) inhibitors
inhibitor of hydrolases acting on C-P bonds
inhibitor of hydrolases acting on C-P bonds (EC 3.11.*)
inhibitor of hydrolases acting on carbon-phosphorus bonds
inhibitor of hydrolases acting on carbon-phosphorus bonds (EC 3.11.*)
inhibitors of hydrolases acting on C-P bonds
inhibitors of hydrolases acting on C-P bonds (EC 3.11.*)
inhibitors of hydrolases acting on carbon-phosphorus bonds
inhibitors of hydrolases acting on carbon-phosphorus bonds (EC 3.11.*)
EC 3.12.* (hydrolases acting on S-S bonds) inhibitor
Any hydrolase inhibitor that interferes with the action of a hydrolase acting on sulfur-sulfur bonds (EC 3.12.*.*).
EC 3.12.* (hydrolases acting on S-S bonds) inhibitors
EC 3.12.* (hydrolases acting on sulfur-sulfur bonds) inhibitor
EC 3.12.* (hydrolases acting on sulfur-sulfur bonds) inhibitors
hydrolases acting on S-S bonds (EC 3.12.*) inhibitor
hydrolases acting on S-S bonds (EC 3.12.*) inhibitors
hydrolases acting on S-S bonds inhibitor
hydrolases acting on S-S bonds inhibitors
hydrolases acting on sulfur-sulfur bonds (EC 3.12.*) inhibitor
hydrolases acting on sulfur-sulfur bonds (EC 3.12.*) inhibitors
hydrolases acting on sulfur-sulfur bonds inhibitor
hydrolases acting on sulfur-sulfur bonds inhibitors
EC 3.13.* (hydrolases acting on C-S bonds) inhibitor
Any hydrolase inhibitor that interferes with the action of a hydrolase acting on carbon-sulfur bonds (EC 3.13.*.*).
EC 3.13.* (hydrolases acting on C-S bonds) inhibitors
EC 3.13.* (hydrolases acting on carbon-sulfur bonds) inhibitor
EC 3.13.* (hydrolases acting on carbon-sulfur bonds) inhibitors
hydrolases acting on C-S bonds (EC 3.13.*) inhibitor
hydrolases acting on C-S bonds (EC 3.13.*) inhibitors
hydrolases acting on C-S bonds inhibitor
hydrolases acting on C-S bonds inhibitors
hydrolases acting on carbon-sulfur bonds (EC 3.13.*) inhibitor
hydrolases acting on carbon-sulfur bonds (EC 3.13.*) inhibitors
hydrolases acting on carbon-sulfur bonds inhibitor
hydrolases acting on carbon-sulfur bonds inhibitors
EC 3.1.1.* (carboxylic ester hydrolase) inhibitor
An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of a carboxylic ester hydrolase (EC 3.1.1.*).
EC 3.1.1.* (carboxylic ester hydrolase) inhibitors
carboxylic ester hydrolase (EC 3.1.1.*) inhibitor
carboxylic ester hydrolase (EC 3.1.1.*) inhibitors
EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor
An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of any phosphoric monoester hydrolase (EC 3.1.3.*).
EC 3.1.3.* (phosphoric monoester hydrolase) inhibitors
inhibitor of phosphoric monoester hydrolase
inhibitor of phosphoric monoester hydrolase (EC 3.1.3.*)
inhibitors of phosphoric monoester hydrolase
inhibitors of phosphoric monoester hydrolase (EC 3.1.3.*)
phosphoric monoester hydrolase (EC 3.1.3.*) inhibitor
phosphoric monoester hydrolase (EC 3.1.3.*) inhibitors
phosphoric monoester hydrolase inhibitor
phosphoric monoester hydrolase inhibitors
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
Any EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of prolyl oligopeptidase (EC 3.4.21.26).
EC 3.4.21.26 (prolyl oligopeptidase) inhibitors
proline-specific endopeptidase inhibitor
proline-specific endopeptidase inhibitors
prolyl oligopeptidase (EC 3.4.21.26) inhibitor
prolyl oligopeptidase (EC 3.4.21.26) inhibitors
EC 3.4.15.* (peptidyl-dipeptidase) inhibitor
Any EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes with the activity of a peptidyl dipeptidase (EC 3.4.15.*).
EC 3.4.15.* (peptidyl-dipeptidase) inhibitors
inhibitor of peptidyl-dipeptidases (EC 3.4.15.*)
inhibitors of peptidyl-dipeptidases (EC 3.4.15.*)
peptidyl-dipeptidase (EC 3.4.15.*) inhibitor
peptidyl-dipeptidase (EC 3.4.15.*) inhibitors
EC 3.1.26.* (endoribonucleases producing 5'-phosphomonoesters) inhibitor
An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of any endoribonuclease producing 5'-phosphomonoesters (EC 3.1.26.*).
EC 3.1.26.* (endoribonucleases producing 5'-phosphomonoesters) inhibitors
endoribonuclease producing 5'-phosphomonoesters (EC 3.1.26.*) inhibitor
endoribonuclease producing 5'-phosphomonoesters (EC 3.1.26.*) inhibitors
endoribonuclease producing 5'-phosphomonoesters inhibitor
endoribonuclease producing 5'-phosphomonoesters inhibitors
An EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes wtih the action of any aminopeptidase (EC 3.4.11.*).
EC 3.4.14.* (dipeptidyl- and tripeptidyl-peptidases) inhibitor
An EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes with the activity of any dipeptidyl- and tripeptidyl-peptidase (EC 3.4.14.*).
EC 3.4.14.* (dipeptidyl- and tripeptidyl-peptidases) inhibitors
EC 3.4.14.*(dipeptidyl-peptidases and tripeptidyl-peptidases) inhibitor
EC 3.4.14.*(dipeptidyl-peptidases and tripeptidyl-peptidases) inhibitors
dipeptidyl- and tripeptidyl-peptidase (EC 3.4.14.*) inhibitor
dipeptidyl- and tripeptidyl-peptidase (EC 3.4.14.*) inhibitors
dipeptidyl- and tripeptidyl-peptidase inhibitor
dipeptidyl- and tripeptidyl-peptidase inhibitors
dipeptidyl- and tripeptidyl-peptidases (EC 3.4.14.*) inhibitor
dipeptidyl- and tripeptidyl-peptidases (EC 3.4.14.*) inhibitors
dipeptidyl- and tripeptidyl-peptidases inhibitor
dipeptidyl- and tripeptidyl-peptidases inhibitors
dipeptidyl-peptidases and tripeptidyl-peptidases (EC 3.4.14.*) inhibitor
dipeptidyl-peptidases and tripeptidyl-peptidases (EC 3.4.14.*) inhibitors
EC 2.4.1.* (hexosyltransferase) inhibitor
An EC 2.4.* (glycosyltransferase) inhibitor that interferes with the action of any hexosyltransferase (EC 2.4.1.*).
EC 2.4.1.* (hexosyltransferase) inhibitors
hexosyltransferase (EC 2.4.1.*) inhibitor
hexosyltransferase (EC 2.4.1.*) inhibitors
EC 2.4.2.* (pentosyltransferase) inhibitor
An EC 2.4.* (glycosyltransferase) inhibitor that interferes with the action of any pentosyltransferase (EC 2.4.2.*).
EC 2.4.2.* (pentosyltransferase) inhibitors
pentosyltransferase (EC 2.4.2.*) inhibitor
pentosyltransferase (EC 2.4.2.*) inhibitors
EC 3.1.27.* (endoribonucleases producing other than 5'-phosphomonoesters) inhibitor
An EC 3.1.* (ester hydrolase) inhibitor that interferes with the activity of any endoribonuclease producing other than a 5'-phosphomonoesters (EC 3.1.27.*).
EC 3.1.27.* (endoribonucleases producing other than 5'-phosphomonoesters) inhibitors
inhibitor of endoribonucleases producing other than 5'-phosphomonoesters
inhibitor of endoribonucleases producing other than 5'-phosphomonoesters (EC 3.1.27.*)
inhibitors of endoribonucleases producing other than 5'-phosphomonoesters
inhibitors of endoribonucleases producing other than 5'-phosphomonoesters (EC 3.1.27.*)
Any EC 3.4.22.* (cysteine endopeptidase) inhibitor that interferes with the activity of caspase-1 (EC 3.4.22.36).
interleukin 1 converting enzyme inhibitor
interleukin 1 converting enzyme inhibitors
interleukin 1beta converting enzyme inhibitor
interleukin 1beta converting enzyme inhibitors
interleukin 1beta precursor proteinase inhibitor
interleukin 1beta precursor proteinase inhibitors
interleukin 1beta-converting endopeptidase inhibitor
interleukin 1beta-converting endopeptidase inhibitors
interleukin 1beta-converting enzyme inhibitor
interleukin 1beta-converting enzyme inhibitors
interleukin-1 beta convertase precursor inhibitor
interleukin-1 beta convertase precursor inhibitors
interleukin-1beta converting enzyme inhibitor
interleukin-1beta converting enzyme inhibitors
interleukin-1beta precursor proteinase inhibitor
interleukin-1beta precursor proteinase inhibitors
precursor interleukin-1beta converting enzyme inhibitor
precursor interleukin-1beta converting enzyme inhibitors
pro-interleukin 1beta proteinase inhibitor
pro-interleukin 1beta proteinase inhibitors
prointerleukin 1beta protease inhibitors
EC 3.4.22.* (cysteine endopeptidase) inhibitor
An EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes with the action of any cysteine endopeptidase (EC 3.4.22.*).
EC 3.4.22.* (cysteine endopeptidase) inhibitors
cysteine endopeptidase (EC 3.4.22.*) inhibitor
cysteine endopeptidase (EC 3.4.22.*) inhibitors
EC 2.5.1.18 (glutathione transferase) inhibitor
An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of a glutathione transferase (EC 2.5.1.18).
EC 2.5.1.18 (glutathione transferase) inhibitors
S-(hydroxyalkyl)glutathione lyase inhibitor
S-(hydroxyalkyl)glutathione lyase inhibitors
glutathione S-alkyl transferase inhibitor
glutathione S-alkyl transferase inhibitors
glutathione S-alkyltransferase inhibitor
glutathione S-alkyltransferase inhibitors
glutathione S-aralkyltransferase inhibitor
glutathione S-aralkyltransferase inhibitors
glutathione S-aryltransferase inhibitors
glutathione transferase (EC 2.5.1.18) inhibitor
glutathione transferase (EC 2.5.1.18) inhibitors
EC 1.14.15.4 (steroid 11beta-monooxygenase) inhibitor
An EC 1.14.15.* (oxidoreductase acting on paired donors, with reduced iron-sulfur protein as one donor, incorporating 1 atom of oxygen) inhibitor that interferes with the action of steroid 11beta-monooxygenase (EC 1.14.15.4).
EC 1.14.15.4 (steroid 11beta-monooxygenase) inhibitors
steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor
steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitors
steroid 11beta/18-hydroxylase inhibitors
steroid,reduced-adrenodoxin:oxygen oxidoreductase (11beta-hydroxylating) inhibitor
steroid,reduced-adrenodoxin:oxygen oxidoreductase (11beta-hydroxylating) inhibitors
EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor
An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide linear amide C-N hydrolase (EC 3.5.1.*).
EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitors
non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitor
non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitors
EC 3.5.2.* (non-peptide cyclic amide C-N hydrolase) inhibitor
An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide cyclic amide C-N hydrolase (EC 3.5.2.*).
EC 3.5.2.* (non-peptide cyclic amide C-N hydrolase) inhibitors
non-peptide cyclic amide C-N hydrolase (EC 3.5.2.*) inhibitor
non-peptide cyclic amide C-N hydrolase (EC 3.5.2.*) inhibitors
non-peptide cyclic amide C-N hydrolase inhibitor
non-peptide cyclic amide C-N hydrolase inhibitors
EC 3.5.4.* (non-peptide cyclic amidine C-N hydrolase) inhibitor
An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide cyclic amidine C-N hydrolase (EC 3.5.4.*).
EC 3.5.4.* (non-peptide cyclic amidine C-N hydrolase) inhibitors
non-peptide cyclic amidine C-N hydrolase (EC 3.5.4.*) inhibitor
non-peptide cyclic amidine C-N hydrolase (EC 3.5.4.*) inhibitors
non-peptide cyclic amidine C-N hydrolase inhibitor
non-peptide cyclic amidine C-N hydrolase inhibitors
EC 3.1.4.12 (sphingomyelin phosphodiesterase) inhibitor
An EC 3.1.4.* (phosphoric diester hydrolase) inhibitor that interferes with the action of sphingomyelin phosphodiesterase (EC 3.1.4.12).
EC 3.1.4.12 (sphingomyelin phosphodiesterase) inhibitors
sphingomyelin cholinephosphohydrolase inhibitor
sphingomyelin cholinephosphohydrolase inhibitors
sphingomyelin phosphodiesterase (EC 3.1.4.12) inhibitor
sphingomyelin phosphodiesterase (EC 3.1.4.12) inhibitors
sphingomyelin phosphodiesterase inhibitor
sphingomyelin phosphodiesterase inhibitors
EC 2.7.11.* (protein-serine/threonine kinase) inhibitor
An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any protein-serine/threonine kinase (EC 2.7.11.*).
EC 2.7.11.* (protein-serine/threonine kinase) inhibitors
protein-serine/threonine kinase (EC 2.7.11.*) inhibitor
protein-serine/threonine kinase (EC 2.7.11.*) inhibitors
protein-serine/threonine kinase inhibitor
EC 2.7.7.* (nucleotidyltransferase) inhibitor
An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any nucleotidyltransferase (EC 2.7.7.*).
EC 2.7.7.* (nucleotidyltransferase) inhibitors
inhibitor of nucleotidyltransferases (EC 2.7.7.*)
inhibitors of nucleotidyltransferases (EC 2.7.7.*)
nucleotidyltransferase (EC 2.7.7.*) inhibitor
nucleotidyltransferase (EC 2.7.7.*) inhibitors
EC 2.7.8.* (transferases for other substituted phosphate groups) inhibitor
An EC 2.7.* (P-containing group transferase) inhibitor that interferes with any enzyme in the EC 2.7.8.* (transferases for other substituted phosphate groups) category.
EC 2.7.8.* (transferases for other substituted phosphate groups) inhibitors
EC 2.7.10.* (protein-tyrosine kinase) inhibitor
An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any protein-tyrosine kinase (EC 2.7.10.*).
EC 2.7.10.* (protein-tyrosine kinase) inhibitors
protein-tyrosine kinase (EC 2.7.10.*) inhibitor
protein-tyrosine kinase (EC 2.7.10.*) inhibitors
EC 2.7.3.* (phosphotransferases with a nitrogenous group as acceptor) inhibitor
An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any phosphotransferases with a nitrogenous group as acceptor (EC 2.7.3.*).
EC 2.7.3.* (phosphotransferases with a nitrogenous group as acceptor) inhibitors
phosphotransferases with a nitrogenous group as acceptor (EC 2.7.3.*) inhibitor
phosphotransferases with a nitrogenous group as acceptor (EC 2.7.3.*) inhibitors
EC 3.2.1.31 (beta-glucuronidase) inhibitor
An EC 3.2.1.* (glycosidase) inhibitor that interferes with the action of beta-glucuronidase (EC 3.2.1.31).
EC 3.2.1.31 (beta-glucuronidase) inhibitors
beta-D-glucuronoside glucuronosohydrolase inhibitor
beta-D-glucuronoside glucuronosohydrolase inhibitors
beta-glucuronidase (EC 3.2.1.31) inhibitor
beta-glucuronidase (EC 3.2.1.31) inhibitors
beta-glucuronide glucuronohydrolase inhibitor
beta-glucuronide glucuronohydrolase inhibitors
EC 6.3.1.* (acid-ammonia/amine ligase) inhibitor
An EC 6.3.* (C-N bond-forming ligase) inhibitor that interferes with the action of any acid-ammonia (or amine) ligase (EC 6.3.1.*).
EC 6.3.1.* (acid-ammonia/amine ligase) inhibitors
acid-ammonia (or amine) ligase inhibitor
acid-ammonia (or amine) ligase inhibitors
An EC 6.4.* (C-C bond-forming ligase) inhibitor that interferes with the action of a carboxylating enzyme (EC 6.4.1.*).
EC 6.4.1.* (C-C bond forming ligase) inhibitor
EC 6.4.1.* (C-C bond forming ligase) inhibitors
EC 6.4.1.* (C-C bond-forming ligase) inhibitors
inhibitor of ligases forming C-C bonds (EC 6.4.1.*)
inhibitors of ligases forming C-C bonds (EC 6.4.1.*)
EC 6.5.1.* (DNA/RNA repair enzymes) inhibitor
An EC 6.5.* (phosphoric ester bond-forming ligase) inhibitor that inhibits the activity of and DNA or RNA repair enzyme (EC 6.5.1.*).
EC 6.5.1.* (DNA/RNA repair enzymes) inhibitors
EC 5.1.1.* (racemases acting on amino acids and derivatives) inhibitor
An EC 5.1.* (racemase/epimerase) inhibitor that interferes with the function of any racemase acting on amino acids or their derivatives (EC 5.1.1.*).
EC 5.1.1.* (racemases acting on amino acids and derivatives) inhibitors
inhibitor of racemases acting on amino acids and derivatives
inhibitor of racemases acting on amino acids and derivatives (EC 5.1.1.*)
inhibitors of racemases acting on amino acids and derivatives
inhibitors of racemases acting on amino acids and derivatives (EC 5.1.1.*)
EC 5.4.3.* (intramolecular transferase transferring amino groups) inhibitor
An EC 5.4.* (intramolecular transferase) inhibitor that interferes with the activity of any intramolecular transferase transferring amino groups (EC 5.4.3.*).
EC 5.4.3.* (intramolecular transferase transferring amino groups) inhibitors
inhibitor of intramolecular transferase transferring amino groups
inhibitor of intramolecular transferase transferring amino groups (EC 5.4.3.*)
inhibitors of intramolecular transferase transferring amino groups
inhibitors of intramolecular transferase transferring amino groups (EC 5.4.3.*)
EC 5.99.1.* (miscellaneous isomerase) inhibitor
An EC 5.99.* (other isomerases) inhibitor that interferes with the activity of any enzyme in the EC 5.99.1.* class.
EC 5.99.1.* (miscellaneous isomerase) inhibitors
An EC 4.4.* (C-S lyase) inhibitor that interferes with the activity of any enzyme in the EC 4.4.1.* category.
An EC 4.3.* (C-N lyase) inhibitor that interferes with the action of any ammonia-lyase (EC 4.3.1.*).
EC 2.5.* (non-methyl-alkyl or aryl transferase) inhibitor
An EC 2.5.* (transferase) inhibitor that inhibits the action of any transferase that transfers an alkyl (other than methyl) or aryl group (EC 2.5.*).
EC 2.5.* (non-methyl-alkyl or aryl transferase) inhibitors
non-methyl-alkyl or aryl transferase (EC 2.5.*) inhibitor
non-methyl-alkyl or aryl transferase (EC 2.5.*) inhibitors
EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor
An EC 1.1.* (oxidoreductase acting on donor CH-OH group) inhibitor that uses NAD(+) or NADP(+) as acceptor (EC 1.1.1.*).
EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+)acceptor) inhibitors
oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor (EC 1.1.1.*) inhibitor
oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor (EC 1.1.1.*) inhibitors
EC 1.1.3.* (oxidoreductase acting on donor CH-OH group, oxygen as acceptor) inhibitor
An EC 1.1.* (oxidoreductase acting on donor CH-OH group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.1.3.*).
EC 1.1.3.* (oxidoreductase acting on donor CH-OH group, oxygen as acceptor) inhibitors
oxidoreductase acting on donor CH-OH group, oxygen as acceptor (EC 1.1.3.*) inhibitor
oxidoreductase acting on donor CH-OH group, oxygen as acceptor (EC 1.1.3.*) inhibitors
EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitor
An EC 1.13.* [oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases)] inhibitor that inhibits the action of any oxidoreductase incorporating 2 atoms of oxygen (EC 1.13.11.*).
EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitors
EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 atoms of oxygen) inhibitor
EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 atoms of oxygen) inhibitors
oxidoreductase acting on single donors and incorporating 2 atoms of oxygen (EC 1.13.11.*) inhibitor
oxidoreductase acting on single donors and incorporating 2 atoms of oxygen (EC 1.13.11.*) inhibitors
EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor
An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any such enzyme incorporating one atom of oxygen and using reduced flavin or flavoprotein as donor (EC 1.14.14.*).
EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitors
EC 1.14.14.* (oxidoreductase acting on paired donors, with incorporation of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor
EC 1.14.14.* (oxidoreductase acting on paired donors, with incorporation of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitors
oxidoreductase acting on paired donors, with incorporation of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor (EC 1.14.14.*) inhibitor
oxidoreductase acting on paired donors, with incorporation of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor (EC 1.14.14.*) inhibitors
EC 1.14.99.* (miscellaneous oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor
An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any enzyme in the EC 1.14.99.* (miscellaneous) category.
EC 1.14.99.* (miscellaneous oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitors
miscellaneous oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.99.*) inhibitor
miscellaneous oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.99.*) inhibitors
EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor
An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any such enzyme incorporating one atom of oxygen and using NADH or NADPH as one donor (EC 1.14.13.*).
EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitors
oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor (EC 1.14.13.*) inhibitor
oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor (EC 1.14.13.*) inhibitors
EC 1.14.15.* (oxidoreductase acting on paired donors, with reduced Fe-S protein as one donor, incorporating 1 O atom) inhibitor
An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any such enzyme with reduced iron-sulfur protein as one donor and incorporating one atom of oxygen (EC 1.14.15.*).
EC 1.14.15.* (oxidoreductase acting on paired donors, with reduced Fe-S protein as one donor, incorporating 1 O atom) inhibitors
EC 1.14.15.* (oxidoreductase acting on paired donors, with reduced iron-sulfur protein as one donor, incorporating 1 atom of oxygen) inhibitor
EC 1.14.15.* (oxidoreductase acting on paired donors, with reduced iron-sulfur protein as one donor, incorporating 1 atom of oxygen) inhibitors
oxidoreductase acting on paired donors, with reduced iron-sulfur protein as one donor, incorporating 1 atom of oxygen (EC 1.14.15.*) inhibitor
oxidoreductase acting on paired donors, with reduced iron-sulfur protein as one donor, incorporating 1 atom of oxygen (EC 1.14.15.*) inhibitors
EC 1.14.18.* (oxidoreductase acting on paired donors, miscellaneous compound as one donor, incorporating 1 atom of oxygen) inhibitor
An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any such enzyme using a miscellaneous compound as one donor and incorporating one atom of oxygen (EC 1.14.18.*).
EC 1.14.18.* (oxidoreductase acting on paired donors, miscellaneous compound as one donor, incorporating 1 atom of oxygen) inhibitors
oxidoreductase acting on paired donors, miscellaneous compound as one donor, incorporating 1 atom of oxygen (EC 1.14.18.*) inhibitor
oxidoreductase acting on paired donors, miscellaneous compound as one donor, incorporating 1 atom of oxygen (EC 1.14.18.*) inhibitors
EC 1.14.16.* (oxidoreductase acting on paired donors, reduced pteridine as one donor, incorporating 1 atom of oxygen) inhibitor
An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any such enzyme using reduced pteridine as one donor and incorporating one atom of oxygen (EC 1.14.16.*).
EC 1.14.16.* (oxidoreductase acting on paired donors, reduced pteridine as one donor, incorporating 1 atom of oxygen) inhibitors
oxidoreductase acting on paired donors, reduced pteridine as one donor, incorporating 1 atom of oxygen (EC 1.14.16.*) inhibitor
oxidoreductase acting on paired donors, reduced pteridine as one donor, incorporating 1 atom of oxygen (EC 1.14.16.*) inhibitors
EC 1.17.4.* (oxidoreductase acting on CH or CH2 with a disulfide as acceptor) inhibitor
An EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitor that interferes with the activity of any such enzyme that uses a disulfide as acceptor (EC 1.17.4.*).
EC 1.17.4.* (oxidoreductase acting on CH or CH2 with a disulfide as acceptor) inhibitors
oxidoreductase acting on CH or CH2 with a disulfide as acceptor (EC 1.17.4.*) inhibitor
oxidoreductase acting on CH or CH2 with a disulfide as acceptor (EC 1.17.4.*) inhibitors
EC 1.17.3.* (oxidoreductase acting on CH or CH2 with oxygen as acceptor) inhibitor
An EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitor that interferes with the function of any such enzyme that uses oxygen as acceptor (EC 1.17.3.*).
EC 1.17.3.* (oxidoreductase acting on CH or CH2 with oxygen as acceptor) inhibitors
oxidoreductase acting on CH or CH2 with oxygen as acceptor (EC 1.17.3.*) inhibitor
oxidoreductase acting on CH or CH2 with oxygen as acceptor (EC 1.17.3.*) inhibitors
EC 1.2.1.* (oxidoreductase acting on donor aldehyde/oxo group with NAD(+) or NADP(+) as acceptor) inhibitor
An EC 1.2.* (oxidoreductase acting on donor aldehyde/oxo group) inhibitor that interferes with the action of any such enzyme using NAD(+) or NADP(+) as acceptor (EC 1.2.1.*).
EC 1.2.1.* (oxidoreductase acting on donor aldehyde/oxo group with NAD(+) or NADP(+) as acceptor) inhibitors
oxidoreductase acting on donor aldehyde/oxo group with NAD(+) or NADP(+) as acceptor (EC 1.2.1.*) inhibitor
oxidoreductase acting on donor aldehyde/oxo group with NAD(+) or NADP(+) as acceptor (EC 1.2.1.*) inhibitors
EC 1.2.3.* (oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor) inhibitor
An EC 1.2.* (oxidoreductase acting on donor aldehyde/oxo group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.2.3.*).
EC 1.2.3.* (oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor) inhibitors
oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor (EC 1.2.3.*) inhibitor
oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor (EC 1.2.3.*) inhibitors
EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor
An EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor that interferes with the action of any such enzyme using NAD(+) or NADP(+) as acceptor (EC 1.3.1.*).
EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor with NAD(+) or NADP(+) as acceptor) inhibitor
EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor with NAD(+) or NADP(+) as acceptor) inhibitors
EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor, NAD(+) or NADP(+) as acceptor) inhibitor
EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor, NAD(+) or NADP(+) as acceptor) inhibitors
EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitors
oxidoreductase acting on CH-CH group of donor with NAD(+) or NADP(+) as acceptor (EC 1.3.1.*) inhibitor
oxidoreductase acting on CH-CH group of donor with NAD(+) or NADP(+) as acceptor (EC 1.3.1.*) inhibitors
EC 1.3.98.* (oxidoreductase acting on donor CH-CH group, with other, known, acceptors) inhibitor
An EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor that interferes with the function of any such enzyme in the EC 1.3.98.* (with other, known, acceptors) category.
EC 1.3.98.* (oxidoreductase acting on CH-CH group of donors, with other, known, acceptors) inhibitor
EC 1.3.98.* (oxidoreductase acting on CH-CH group of donors, with other, known, acceptors) inhibitors
EC 1.3.98.* (oxidoreductase acting on donor CH-CH group, with other, known, acceptors) inhibitors
oxidoreductase acting on CH-CH group of donors, with other, known, acceptors (EC 1.3.98.*) inhibitor
oxidoreductase acting on CH-CH group of donors, with other, known, acceptors (EC 1.3.98.*) inhibitors
EC 1.3.99.* (oxidoreductase acting on donor CH-CH group, with other acceptors) inhibitor
An EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor that interferes with the function of any such enzyme in the EC 1.3.98.* (with other acceptors) category.
EC 1.3.99.* (oxidoreductase acting on donor CH-CH group with other acceptors) inhibitors
EC 1.3.99.* (oxidoreductase acting on donor CH-CH group, with other acceptors) inhibitors
oxidoreductase acting on donor CH-CH group with other acceptors (EC 1.3.99.*) inhibitor
oxidoreductase acting on donor CH-CH group with other acceptors (EC 1.3.99.*) inhibitors
EC 1.3.3.* (oxidoreductase acting on donor CH-CH group, oxygen as acceptor) inhibitor
An EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.3.3.*).
EC 1.3.3.* (oxidoreductase acting on donor CH-CH group with oxygen as acceptor) inhibitor
EC 1.3.3.* (oxidoreductase acting on donor CH-CH group with oxygen as acceptor) inhibitors
EC 1.3.3.* (oxidoreductase acting on donor CH-CH group, oxygen as acceptor) inhibitors
oxidoreductase acting on donor CH-CH group with oxygen as acceptor (EC 1.3.3.*) inhibitor
oxidoreductase acting on donor CH-CH group with oxygen as acceptor (EC 1.3.3.*) inhibitors
EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor
An EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.4.3.*).
EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitors
oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor (EC 1.4.3.*) inhibitor
oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor (EC 1.4.3.*) inhibitors
EC 1.4.4.* (oxidoreductase acting on donor CH-NH2 group, a disulfide as acceptor) inhibitor
An EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor that interferes with the action of any such enzyme using a disulfide as acceptor (EC 1.4.4.*).
EC 1.4.4.* (oxidoreductase acting on donor CH-NH2 group, a disulfide as acceptor) inhibitors
oxidoreductase acting on donor CH-NH2 group, a disulfide as acceptor (EC 1.4.4.*) inhibitor
oxidoreductase acting on donor CH-NH2 group, a disulfide as acceptor (EC 1.4.4.*) inhibitors
EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor) inhibitor
An EC 1.5.* (oxidoreductase acting on donor CH-NH group) inhibitor that interferes with the action of any such enzyme using NAD(+) or NADP(+) as acceptor (EC 1.5.1.*).
EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor) inhibitors
oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor (EC 1.5.1.*) inhibitor
oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor (EC 1.5.1.*) inhibitors
EC 1.6.5.* (oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor) inhibitor
An EC 1.6.* (oxidoreductase acting on NADH or NADPH) inhibitor that interferes with the action of any such enzyme using a quinone or similar as acceptor (EC 1.6.5.*).
EC 1.6.5.* (oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor) inhibitors
oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor (EC 1.6.5.*) inhibitor
oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor (EC 1.6.5.*) inhibitors
EC 1.6.3.* (oxidoreductase acting on NADH or NADPH with oxygen as acceptor) inhibitor
An EC 1.6.* (oxidoreductase acting on NADH or NADPH) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.6.3.*).
EC 1.6.3.* (oxidoreductase acting on NADH or NADPH with oxygen as acceptor) inhibitors
oxidoreductase acting on NADH or NADPH with oxygen as acceptor (EC 1.6.3.*) inhibitor
oxidoreductase acting on NADH or NADPH with oxygen as acceptor (EC 1.6.3.*) inhibitors
EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD(+) or NADP(+) as acceptor) inhibitor
An EC 1.8.* (oxidoreductase acting on sulfur group of donors) inhibitor that interferes with the action of any such enzyme using NAD(+) or NADP(+) as acceptor (EC 1.8.1.*).
EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD(+) or NADP(+) as acceptor) inhibitors
oxidoreductase acting on sulfur group of donors, NAD(+) or NADP(+) as acceptor (EC 1.8.1.*) inhibitor
oxidoreductase acting on sulfur group of donors, NAD(+) or NADP(+) as acceptor (EC 1.8.1.*) inhibitors
EC 1.9.3.* (oxidoreductase acting on donor heme group, oxygen as acceptor) inhibitor
An EC 1.9.* (oxidoreductase acting on donor heme group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.9.3.*).
EC 1.9.3.* (oxidoreductase acting on donor heme group, oxygen as acceptor) inhibitors
oxidoreductase acting on donor heme group, oxygen as acceptor (EC 1.9.3.*) inhibitor
oxidoreductase acting on donor heme group, oxygen as acceptor (EC 1.9.3.*) inhibitors
EC 2.1.1.* (methyltransferases) inhibitor
An EC 2.1.* (C1-transferase) inhibitor that interferes with the action of any methyltransferase (EC 2.1.1.*).
EC 2.1.1.* (methyltransferase) inhibitor
EC 2.1.1.* (methyltransferase) inhibitors
EC 2.1.1.* (methyltransferases) inhibitors
methyltransferase (EC 2.1.1.*) inhibitor
methyltransferase (EC 2.1.1.*) inhibitors
EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor
An EC 2.1.* (C1-transferase) inhibitor that interferes with the action of any hydroxymethyl-, formyl- and related transferase (EC 2.1.2.*).
EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitors
hydroxymethyl-, formyl- and related transferases (EC 2.1.2.*) inhibitor
hydroxymethyl-, formyl- and related transferases (EC 2.1.2.*) inhibitors
EC 2.2.1.* (transketolase/transaldolase) inhibitor
An EC 2.2.* (aldehyde or ketone transferase) inhibitor that interferes with the action of any (transketolase or transaldolase (EC 2.2.1.*).
EC 2.2.1.* (transketolase/transaldolase) inhibitors
EC 2.2.1.* (transketolases and transaldolases) inhibitor
EC 2.2.1.* (transketolases and transaldolases) inhibitors
transketolase/transaldolase (EC 2.2.1.*) inhibitor
transketolase/transaldolase (EC 2.2.1.*) inhibitors
EC 2.3.2.* (aminoacyltransferase) inhibitor
An EC 2.3.* (acyltransferase) inhibitor that interferes with the action of any aminoacyltransferase (EC 2.3.2.*).
EC 2.3.2.* (aminoacyltransferase) inhibitors
aminoacyltransferase (EC 2.3.2.*) inhibitor
aminoacyltransferase (EC 2.3.2.*) inhibitors
EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor
An EC 2.3.* (acyltransferase) inhibitor that inhibits the action of any acyltransferase transferring groups other than amino-acyl groups (EC 2.3.1.*).
EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitors
acyltransferase transferring other than amino-acyl group EC 2.3.1.* inhibitor
acyltransferase transferring other than amino-acyl group EC 2.3.1.* inhibitors
An EC 2.6.* (nitrogenous group transferase) inhibitor that inhibits the action of any transaminase (EC 2.6.1.*).
EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor
An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any phosphotransferase with an alcohol group as acceptor (EC 2.7.1.*).
EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitors
phosphotransferases with an alcohol group as acceptor (EC 2.7.1.*) inhibitor
phosphotransferases with an alcohol group as acceptor (EC 2.7.1.*) inhibitors
EC 2.4.99.* (glycosyltransferases transferring other glycosyl groups) inhibitor
An EC 2.4.* (glycosyltransferase) inhibitor that interferes with the activity of any glycosyltransferase in the EC 2.4.99.* (transferring other glycosyl groups) category.
EC 2.4.99.* (glycosyltransferases transferring other glycosyl groups) inhibitors
glycosyltransferases transferring other glycosyl groups (EC 2.4.99.*) inhibitor
glycosyltransferases transferring other glycosyl groups (EC 2.4.99.*) inhibitors
EC 3.11.1.* (hydrolases acting on C-P bonds of phosphono-acetaldehyde, -acetate, or -pyruvate) inhibitor
An EC 3.11.* (hydrolases acting on C-P bonds) inhibitor that interferes with the activity of any phosphonoacetaldehyde, phosphonoacetate, or phosphonopyruvate hydrolase (EC 3.11.1.*).
EC 3.11.1.* (hydrolases acting on C-P bonds of phosphono-acetaldehyde, -acetate, or -pyruvate) inhibitors
hydrolases acting on C-P bonds of phosphono-acetaldehyde, -acetate, or -pyruvate (EC 3.11.1.*) inhibitor
hydrolases acting on C-P bonds of phosphono-acetaldehyde, -acetate, or -pyruvate (EC 3.11.1.*) inhibitors
EC 3.4.23.* (aspartic endopeptidase) inhibitor
An EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes with the action of any aspartic endopeptidase (EC 3.4.23.*).
EC 3.4.23.* (aspartic endopeptidase) inhibitors
EC 3.4.23.* (aspartic endopeptidases) inhibitor
EC 3.4.23.* (aspartic endopeptidases) inhibitors
aspartic endopeptidase (EC 3.4.23.*) inhibitor
aspartic endopeptidase (EC 3.4.23.*) inhibitors
aspartic endopeptidases (EC 3.4.23.*) inhibitor
aspartic endopeptidases (EC 3.4.23.*) inhibitors
EC 3.4.11.14 (cytosol alanyl aminopeptidase) inhibitor
An EC 3.4.11.* (aminopeptidase) inhibitor that interferes with the action of cytosol alanyl aminopeptidase (EC 3.4.11.14).
EC 3.4.11.14 (cytosol alanyl aminopeptidase) inhibitors
cytosol alanyl aminopeptidase (EC 3.4.11.14) inhibitor
cytosol alanyl aminopeptidase (EC 3.4.11.14) inhibitors
cytosol alanyl aminopeptidase inhibitors
puromycin-sensitive aminopeptidase inhibitor
puromycin-sensitive aminopeptidase inhibitors
soluble alanyl aminopeptidase inhibitors
thiol-activated aminopeptidase inhibitor
thiol-activated aminopeptidase inhibitors
EC 3.4.14.2 (dipeptidyl-peptidase II) inhibitor
An EC 3.4.14.* (dipeptidyl- and tripeptidyl-peptidases) inhibitor that interferes with the action of dipeptidyl-peptidase II (EC 3.4.14.2).
EC 3.4.14.2 (dipeptidyl-peptidase II) inhibitors
dipeptidyl(amino)peptidase II inhibitors
dipeptidyl-peptidase II (EC 3.4.14.2) inhibitor
dipeptidyl-peptidase II (EC 3.4.14.2) inhibitors
EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor
An EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor that interferes with the action of any such enzyme that catalyses transmembrane movement of substances (EC 3.6.3.*).
EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitors
acid anhydride hydrolase catalysing transmembrane movement of substances (EC 3.6.3.*) inhibitor
acid anhydride hydrolase catalysing transmembrane movement of substances (EC 3.6.3.*) inhibitors
EC 1.14.14.1 (unspecific monooxygenase) inhibitor
An EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor that interferes with the action of an unspecified monooxygenase (EC 1.14.14.1).
EC 1.14.14.1 (unspecific monooxygenase) inhibitors
flavoprotein-linked monooxygenase inhibitor
flavoprotein-linked monooxygenase inhibitors
substrate,reduced-flavoprotein:oxygen oxidoreductase (RH-hydroxylating or -epoxidising) inhibitor
substrate,reduced-flavoprotein:oxygen oxidoreductase (RH-hydroxylating or -epoxidising) inhibitors
unspecific monooxygenase (EC 1.14.14.1) inhibitor
unspecific monooxygenase (EC 1.14.14.1) inhibitors
EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor
An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the function of any such enzyme using 2-oxoglutarate as one donor and incorporating one atom each of oxygen into both donors (EC 1.14.11.*).
EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitors
EC 1.14.11.* (oxidoreductase acting on paired donors, with 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors) inhibitor
EC 1.14.11.* (oxidoreductase acting on paired donors, with 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors) inhibitors
oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors (EC 1.14.11.*) inhibitor
oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors (EC 1.14.11.*) inhibitors
oxidoreductase acting on paired donors, with 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors (EC 1.14.11.*) inhibitor
oxidoreductase acting on paired donors, with 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors (EC 1.14.11.*) inhibitors
An EC 4.1.* (C-C lyase) inhibitor that interferes with the action of any carboxy-lyase (EC 4.1.1.*).
An EC 4.2.* (C-O lyase) inhibitor that interferes with the action of any hydro-lyase (EC 4.2.1.*).
A drug which increases the blood glucose level.
EC 1.1.3.9 (galactose oxidase) inhibitor
An EC 1.1.3.* (oxidoreductase acting on donor CH-OH group, oxygen as acceptor) inhibitor that interferes with the action of galactose oxidase (EC 1.1.3.9).
D-galactose:oxygen 6-oxidoreductase inhibitor
D-galactose:oxygen 6-oxidoreductase inhibitors
EC 1.1.3.9 (galactose oxidase) inhibitors
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
EC 3.4.13.19 (membrane dipeptidase) inhibitor
An EC 3.4.13.* (dipeptidase) inhibitor that interferes with the action of membrane dipeptidase (EC 3.4.13.19).
EC 3.4.13.19 (membrane dipeptidase) inhibitors
glycosyl-phosphatidylinositol-anchored renal dipeptidase inhibitors
membrane dipeptidase (EC 3.4.13.19) inhibitor
membrane dipeptidase (EC 3.4.13.19) inhibitors
An enzyme inhibitor that interferes with one or more steps in a metabolic pathway.
EC 3.6.4.* (hydrolases acting on ATP; involved in cellular and subcellular movement) inhibitor
An EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor that interferes with the action of any such enzyme acting on ATP and involved in cellular and subcellular movement (EC 3.6.4.*).
EC 3.6.4.* (hydrolase acting on ATP; involved in cellular and subcellular movement) inhibitor
EC 3.6.4.* (hydrolase acting on ATP; involved in cellular and subcellular movement) inhibitors
EC 3.6.4.* (hydrolases acting on ATP; involved in cellular and subcellular movement) inhibitors
hydrolases acting on ATP; involved in cellular and subcellular movement (EC 3.6.4.*) inhibitor
hydrolases acting on ATP; involved in cellular and subcellular movement (EC 3.6.4.*) inhibitors
EC 3.6.4.10 (non-chaperonin molecular chaperone ATPase) inhibitor
ATP phosphohydrolase (polypeptide-polymerising) inhibitor
ATP phosphohydrolase (polypeptide-polymerising) inhibitors
ATP phosphohydrolase (polypeptide-polymerizing) inhibitor
ATP phosphohydrolase (polypeptide-polymerizing) inhibitors
An EC 3.6.4.* (hydrolases acting on ATP; involved in cellular and subcellular movement) inhibitor that interferes with the action of a non-chaperonin molecular chaperone ATPase (EC 3.6.4.10).
EC 3.6.4.10 (non-chaperonin molecular chaperone ATPase) inhibitors
molecular chaperone Hsc70 ATPase inhibitor
molecular chaperone Hsc70 ATPase inhibitors
non-chaperonin molecular chaperone ATPase (EC 3.6.4.10) inhibitor
non-chaperonin molecular chaperone ATPase (EC 3.6.4.10) inhibitors
An EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of trypsin (EC 3.4.21.4).
Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds.
Any fungal metabolite produced during a metabolic reaction in the mould, Aspergillus.
Any fungal metabolite produced during a metabolic reaction in the mould, Chaetomium.
Any fungal metabolite produced during a metabolic reaction in Penicillium.
Any human metabolite produced by metabolism of a xenobiotic compound in humans.
Any fungal metabolite produced by metabolism of a xenobiotic compound in fungi.
Any prokaryotic metabolite produced during a metabolic reaction in bacteria.
Any bacterial metabolite produced during a metabolic reaction in Escherichia coli.
Any bacterial metabolite produced during a metabolic reaction in Streptococcus pneumoniae.
Streptococcus pneumoniae secondary metabolites
Any bacterial metabolite produced by metabolism of a xenobiotic compound in bacteria.
corticotropin-releasing factor receptor antagonist
A hormone antagonist that blocks corticotropin-releasing factor receptors
corticotropin-releasing factor receptor antagonists
A synthetic or semi-synthetic compound that has oestrogenic activity.
Any compound produced by a plant that happens to have estrogenic activity.
Any compound produced by a fungus that happens to have estrogenic activity.
An antagonist that binds to and activates aryl hydrocarbon receptors (AhRs).
EC 1.10.99.* (oxidoreductases acting on diphenols and related substances as donors, other acceptors) inhibitor
An EC 1.10.* (oxidoreductase acting on diphenols and related substances as donors) inhibitor that interferes with the action of any such enzyme in the EC 1.10.99.* category.
EC 1.10.99.* (oxidoreductases acting on diphenols and related substances as donors, other acceptors) inhibitors
oxidoreductases acting on diphenols and related substances as donors, other acceptors (EC 1.10.99.*) inhibitor
oxidoreductases acting on diphenols and related substances as donors, other acceptors (EC 1.10.99.*) inhibitors
EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor
1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide:quinone oxidoreductase inhibitor
1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide:quinone oxidoreductase inhibitors
An EC 1.10.99.* (oxidoreductases acting on diphenols and related substances as donors, other acceptors) inhibitor that interferes with the action of ribosyldihydronicotinamide dehydrogenase (quinone), EC 1.10.99.2.
EC 1.10.99.2 (ribosyldihydronicotinamide dehydrogenase (quinone)) inhibitor
EC 1.10.99.2 (ribosyldihydronicotinamide dehydrogenase (quinone)) inhibitors
EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitors
N-ribosyldihydronicotinamide dehydrogenase (quinone) inhibitor
N-ribosyldihydronicotinamide dehydrogenase (quinone) inhibitors
NAD(P)H:quinone oxidoreductase-2 inhibitor
NAD(P)H:quinone oxidoreductase-2 inhibitors
NAD(P)H:quinone oxidoreductase2 inhibitor
NAD(P)H:quinone oxidoreductase2 inhibitors
ribosyldihydronicotinamide dehydrogenase (quinone) (EC 1.10.99.2) inhibitor
ribosyldihydronicotinamide dehydrogenase (quinone) (EC 1.10.99.2) inhibitors
EC 2.3.3.* (acyltransferase converting acyl to alkyl group on transfer) inhibitor
An EC 2.3.* (acyltransferase) inhibitor that interferes with the action of an acyltransferase which converts the acyl group to an alkyl group on transfer (EC 2.3.3.*).
EC 2.3.3.* (acyltransferase converting acyl to alkyl group on transfer) inhibitors
acyltransferase converting acyl to alkyl group on transfer (EC 2.3.3.*) inhibitor
acyltransferase converting acyl to alkyl group on transfer (EC 2.3.3.*) inhibitors
EC 2.3.3.1 [citrate (Si)-synthase] inhibitor
An EC 2.3.3.* (acyltransferase converting acyl to alkyl group on transfer) inhibitor that interferes with the action of citrate (Si)-synthase, EC 2.3.3.1.
EC 2.3.3.1 (citrate (Si)-synthase) inhibitor
EC 2.3.3.1 (citrate (Si)-synthase) inhibitors
EC 2.3.3.1 [citrate (Si)-synthase] inhibitors
acetyl-CoA:oxaloacetate C-acetyltransferase [thioester-hydrolysing, (pro-S)-carboxymethyl forming] inhibitor
acetyl-CoA:oxaloacetate C-acetyltransferase [thioester-hydrolysing, (pro-S)-carboxymethyl forming] inhibitors
citrate (Si)-synthase (EC 2.3.3.1) inhibitor
citrate (Si)-synthase (EC 2.3.3.1) inhibitors
citrate oxaloacetate-lyase [(pro-3S)-CH2COO->acetyl-CoA] inhibitor
citrate oxaloacetate-lyase [(pro-3S)-CH2COO->acetyl-CoA] inhibitors
citrate oxaloacetate-lyase, CoA-acetylating inhibitor
citrate oxaloacetate-lyase, CoA-acetylating inhibitors
EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor
4-nitrophenylphosphatase (EC 3.1.3.41) inhibitor
4-nitrophenylphosphatase (EC 3.1.3.41) inhibitors
4-nitrophenylphosphate phosphohydrolase inhibitor
4-nitrophenylphosphate phosphohydrolase inhibitors
An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of 4-nitrophenylphosphatase (EC 3.1.3.41).
EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitors
Ecto-p-nitrophenyl phosphatase inhibitor
Ecto-p-nitrophenyl phosphatase inhibitors
p-nitrophenylphosphate phosphohydrolase inhibitor
p-nitrophenylphosphate phosphohydrolase inhibitors
A compound that alters the structure of mucus so as to decrease its viscosity and thereby facilitate its removal by ciliary action and expectoration. Compare with antitussives, which suppress the cough reflex, and expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing.
Compounds that are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing. Compare with mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration, and antitussives, which suppress the cough reflex.
EC 1.4.7.* (oxidoreductase acting on donor CH-NH2 group, Fe-S protein as acceptor) inhibitor
An EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor that interferes with the action of any such enzyme using a iron-sulfur protein as acceptor (EC 1.4.7.*).
EC 1.4.7.* (oxidoreductase acting on donor CH-NH2 group, Fe-S protein as acceptor) inhibitors
inhibitor of oxidoreductase acting on donor CH-NH2 group, Fe-S protein as acceptor
inhibitors of oxidoreductase acting on donor CH-NH2 group, Fe-S protein as acceptor
oxidoreductase acting on donor CH-NH2 group, Fe-S protein as acceptor (EC 1.4.7.*) inhibitor
oxidoreductase acting on donor CH-NH2 group, Fe-S protein as acceptor (EC 1.4.7.*) inhibitors
EC 2.5.1.49 (O-acetylhomoserine aminocarboxypropyltransferase) inhibitor
An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of O-acetylhomoserine aminocarboxypropyltransferase (EC 2.5.1.49).
EC 2.5.1.49 (O-acetylhomoserine aminocarboxypropyltransferase) inhibitors
O-acetyl-L-homoserine acetate-lyase (adding methanethiol) inhibitor
O-acetyl-L-homoserine acetate-lyase (adding methanethiol) inhibitors
O-acetyl-L-homoserine sulfhydrolase inhibitor
O-acetyl-L-homoserine sulfhydrolase inhibitors
O-acetyl-L-homoserine:methanethiol 3-amino-3-carboxypropyltransferase inhibitor
O-acetyl-L-homoserine:methanethiol 3-amino-3-carboxypropyltransferase inhibitors
O-acetylhomoserine (thiol)-lyase inhibitor
O-acetylhomoserine (thiol)-lyase inhibitors
O-acetylhomoserine aminocarboxypropyltransferase (EC 2.5.1.49) inhibitor
O-acetylhomoserine aminocarboxypropyltransferase (EC 2.5.1.49) inhibitors
O-acetylhomoserine aminocarboxypropyltransferase inhibitor
O-acetylhomoserine aminocarboxypropyltransferase inhibitors
O-acetylhomoserine sulfhydrolase inhibitor
O-acetylhomoserine sulfhydrolase inhibitors
EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor
An EC 4.3.1.* (ammonia-lyase) inhibitor that interferes with the action of serine-sulfate ammonia-lyase (EC 4.3.1.10).
EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitors
L-serine-O-sulfate ammonia-lyase (pyruvate-forming) inhibitor
L-serine-O-sulfate ammonia-lyase (pyruvate-forming) inhibitors
serine-sulfate ammonia-lyase (EC 4.3.1.10) inhibitor
serine-sulfate ammonia-lyase (EC 4.3.1.10) inhibitors
EC 1.3.5.* (oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor) inhibitor
An EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor that interferes with the action of any such enzyme using a quinone or related compound as acceptor (EC 1.3.5.*).
EC 1.3.5.* (oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor) inhibitors
inhibitor of oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor
inhibitor of oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor (EC 1.3.5.*)
inhibitors of oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor
inhibitors of oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor (EC 1.3.5.*)
oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor (EC 1.3.5.*) inhibitor
oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor (EC 1.3.5.*) inhibitors
EC 1.3.5.2 [dihydroorotate dehydrogenase (quinone)] inhibitor
(S)-dihydroorotate:(acceptor) oxidoreductase inhibitor
(S)-dihydroorotate:(acceptor) oxidoreductase inhibitors
(S)-dihydroorotate:acceptor oxidoreductase inhibitor
(S)-dihydroorotate:acceptor oxidoreductase inhibitors
(S)-dihydroorotate:quinone oxidoreductase inhibitor
(S)-dihydroorotate:quinone oxidoreductase inhibitors
An EC 1.3.5.* (oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor) inhibitor that interferes with the action of dihydroorotate dehydrogenase (quinone), EC 1.3.5.2.
EC 1.3.5.2 (dihydroorotate dehydrogenase (quinone)) inhibitor
EC 1.3.5.2 (dihydroorotate dehydrogenase (quinone)) inhibitors
EC 1.3.5.2 [dihydroorotate dehydrogenase (quinone)] inhibitors
dihydroorotate:ubiquinone oxidoreductase inhibitor
dihydroorotate:ubiquinone oxidoreductase inhibitors
EC 1.10.2.* (oxidoreductase acting on diphenols and related substances as donors with a cytochrome as acceptor) inhibitor
An EC 1.10.* (oxidoreductase acting on diphenols and related substances as donors) inhibitor that interferes with the action of any such enzyme using a cytochrome as acceptor (EC 1.10.2.*).
EC 1.10.2.* (oxidoreductase acting on diphenols and related substances as donors with a cytochrome as acceptor) inhibitors
inhibitor of an oxidoreductase acting on diphenols and related substances as donors with a cytochrome as acceptor (EC 1.10.2.*)
inhibitors of an oxidoreductase acting on diphenols and related substances as donors with a cytochrome as acceptor (EC 1.10.2.*)
oxidoreductase acting on diphenols and related substances as donors with a cytochrome as acceptor (EC 1.10.2.*) inhibitor
oxidoreductase acting on diphenols and related substances as donors with a cytochrome as acceptor (EC 1.10.2.*) inhibitors
EC 1.10.2.2 (quinol--cytochrome-c reductase) inhibitor
An EC 1.10.2.* (oxidoreductase acting on diphenols and related substances as donors with a cytochrome as acceptor) inhibitor that interferes with the action of quinol--cytochrome-c reductase (EC 1.10.2.2).
EC 1.10.2.2 (quinol--cytochrome-c reductase) inhibitors
inhibitor of quinol--cytochrome-c reductase (EC 1.10.2.2)
inhibitors of quinol--cytochrome-c reductase (EC 1.10.2.2)
quinol--cytochrome-c reductase (EC 1.10.2.2) inhibitor
quinol--cytochrome-c reductase (EC 1.10.2.2) inhibitors
EC 1.1.1.141 [15-hydroxyprostaglandin dehydrogenase (NAD(+))] inhibitor
(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-13-enoate:NAD(+) 15-oxidoreductase inhibitor
(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-13-enoate:NAD(+) 15-oxidoreductase inhibitors
(5Z,13E,15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate:NAD(+) 15-oxidoreductase inhibitor
(5Z,13E,15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate:NAD(+) 15-oxidoreductase inhibitors
11alpha,15-dihydroxy-9-oxoprost-13-enoate:NAD(+) 15-oxidoreductase inhibitor
11alpha,15-dihydroxy-9-oxoprost-13-enoate:NAD(+) 15-oxidoreductase inhibitors
15-hydroxyprostaglandin dehydrogenase (NAD(+)) (EC 1.1.1.141) inhibitor
15-hydroxyprostaglandin dehydrogenase (NAD(+)) (EC 1.1.1.141) inhibitors
15-hydroxyprostaglandin dehydrogenase (NAD(+)) inhibitor
15-hydroxyprostaglandin dehydrogenase (NAD(+)) inhibitors
15-hydroxyprostaglandin dehydrogenase inhibitor
15-hydroxyprostaglandin dehydrogenase inhibitors
15-hydroxyprostanoic dehydrogenase inhibitor
15-hydroxyprostanoic dehydrogenase inhibitors
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of 15-hydroxyprostaglandin dehydrogenase (NAD(+)) (EC 1.1.1.141).
EC 1.1.1.141 [15-hydroxyprostaglandin dehydrogenase (NAD(+))] inhibitors
NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase (type I) inhibitor
NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase (type I) inhibitors
NAD-specific 15-hydroxyprostaglandin dehydrogenase inhibitor
NAD-specific 15-hydroxyprostaglandin dehydrogenase inhibitors
EC 1.21.3.* (oxidoreductase acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor) inhibitor
An EC 1.21.* (oxidoreductase acting on X-H and Y-H to form an X-Y bond) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.21.3.*).
EC 1.21.3.* (oxidoreductase acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor) inhibitors
inhibitor of oxidoreductase acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor
inhibitor of oxidoreductase acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor (EC 1.21.3.*)
inhibitors of oxidoreductase acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor
inhibitors of oxidoreductase acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor (EC 1.21.3.*)
oxidoreductase acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor (EC 1.21.3.*) inhibitor
oxidoreductase acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor (EC 1.21.3.*) inhibitors
EC 1.21.3.3 (reticuline oxidase) inhibitor
(S)-reticuline:oxygen oxidoreductase (methylene-bridge-forming) inhibitor
(S)-reticuline:oxygen oxidoreductase (methylene-bridge-forming) inhibitors
An EC 1.21.3.* (oxidoreductase acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor) inhibitor that interferes with the action of reticuline oxidase (EC 1.21.3.3, previously EC 1.5.3.9).
EC 1.21.3.3 (reticuline oxidase) inhibitors
berberine-bridge-forming enzyme inhibitor
berberine-bridge-forming enzyme inhibitors
reticuline oxidase (EC 1.21.3.3) inhibitor
reticuline oxidase (EC 1.21.3.3) inhibitors
tetrahydroprotoberberine synthase inhibitor
tetrahydroprotoberberine synthase inhibitors
EC 2.1.1.116 [3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase] inhibitor
3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase (EC 2.1.1.116) inhibitor
3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase (EC 2.1.1.116) inhibitors
An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of 3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase (EC 2.1.1.116).
EC 2.1.1.116 [3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase] inhibitors
S-adenosyl-L-methionine:3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase inhibitor
S-adenosyl-L-methionine:3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase inhibitors
ATP:[IkappaB protein] phosphotransferase
ATP:[IkappaB protein] phosphotransferase inhibitor
An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of IkappaB kinase (EC 2.7.11.10).
EC 2.7.11.10 (IkappaB kinase) inhibitors
IkappaB kinase (EC 2.7.11.10) inhibitors
EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor
(S)-tetrahydroprotoberberine N-methyltransferase (EC 2.1.1.122) inhibitor
(S)-tetrahydroprotoberberine N-methyltransferase (EC 2.1.1.122) inhibitors
(S)-tetrahydroprotoberberine N-methyltransferase inhibitor
(S)-tetrahydroprotoberberine N-methyltransferase inhibitors
An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of (S)-tetrahydroprotoberberine N-methyltransferase (EC 2.1.1.122).
EC 2.1.1.122 ((S)-tetrahydroprotoberberine N-methyltransferase) inhibitor
EC 2.1.1.122 ((S)-tetrahydroprotoberberine N-methyltransferase) inhibitors
EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitors
S-adenosyl-L-methionine:(S)-7,8,13,14-tetrahydroprotoberberine cis-N-methyltransferase inhibitor
S-adenosyl-L-methionine:(S)-7,8,13,14-tetrahydroprotoberberine cis-N-methyltransferase inhibitors
tetrahydroprotoberberine cis-N-methyltransferase inhibitor
tetrahydroprotoberberine cis-N-methyltransferase inhibitors
EC 3.5.5.* (hydrolase acting on C-N bonds in nitriles) inhibitor
An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any such enzyme acting on the C-N bond of nitriles (EC 3.5.5.*).
EC 3.5.5.* (hydrolase acting on C-N bonds in nitriles) inhibitors
hydrolase acting on C-N bonds in nitriles (EC 3.5.5.*) inhibitor
hydrolase acting on C-N bonds in nitriles (EC 3.5.5.*) inhibitors
inhibitor of hydrolases acting on C-N bonds in nitriles
inhibitors of hydrolases acting on C-N bonds in nitriles
An EC 3.5.5.* (hydrolase acting on C-N bonds in nitriles) inhibitor that interferes with the action of nitrilase (EC 3.5.5.1).
EC 1.1.1.189 (prostaglandin-E2 9-reductase) inhibitor
(5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP(+) 9-oxidoreductase inhibitor
(5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP(+) 9-oxidoreductase inhibitors
9-keto-prostaglandin E2 reductase inhibitor
9-keto-prostaglandin E2 reductase inhibitors
9-ketoprostaglandin reductase inhibitors
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of prostaglandin-E2 9-reductase (EC 1.1.1.189).
EC 1.1.1.189 (prostaglandin-E2 9-reductase) inhibitors
prostaglandin E 9-ketoreductase inhibitor
prostaglandin E 9-ketoreductase inhibitors
prostaglandin E2-9-oxoreductase inhibitor
prostaglandin E2-9-oxoreductase inhibitors
prostaglandin-E2 9-reductase (EC 1.1.1.189) inhibitor
prostaglandin-E2 9-reductase (EC 1.1.1.189) inhibitors
reductase, 15-hydroxy-9-oxoprostaglandin inhibitor
reductase, 15-hydroxy-9-oxoprostaglandin inhibitors
An agonist that selectively binds to and activates the Toll-like receptor 2 (TLR 2, TLR-2) protein.
A dye used in microscopic or electron microscopic examination of cells and tissues to give contrast and to highlight particular features of interest, such as nuclei and cytoplasm.
A food additive that imparts colour to food. In European countries, E-numbers for permitted food colours are from E 100 to E 199, divided into yellows (E 100-109), oranges (E 110-119), reds (E 120-129), blues and violets (E 130-139), greens (E 140-149), browns and blacks (E 150-159), and others (E 160-199).
EC 2.7.1.33 (pantothenate kinase) inhibitor
ATP:(R)-pantothenate 4'-phosphotransferase inhibitor
ATP:(R)-pantothenate 4'-phosphotransferase inhibitors
ATP:pantothenate 4'-phosphotransferase inhibitor
ATP:pantothenate 4'-phosphotransferase inhibitors
An EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor that interferes with the action of pantothenate kinase (EC 2.7.1.33).
EC 2.7.1.33 (pantothenate kinase) inhibitors
pantothenate kinase (EC 2.7.1.33) inhibitor
pantothenate kinase (EC 2.7.1.33) inhibitors
pantothenate kinase (phosphorylating) inhibitor
pantothenate kinase (phosphorylating) inhibitors
EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor
An EC 3.4.24.* (metalloendopeptidase) inhibitor that interferes with the action of anthrax lethal factor endopeptidase (EC 3.4.24.83).
EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitors
anthrax lethal factor endopeptidase (EC 3.4.24.83) inhibitor
anthrax lethal factor endopeptidase (EC 3.4.24.83) inhibitors
Any protective agent that is able to prevent damage to the heart.
An agonist that selectively binds to and activates a pregnane X receptor.
Any compound that activates UDP-glucuronosyltransferase (EC 2.4.1.17).
An agonist that selectively binds to and activates androstane receptors.
constitutive androstane receptor agonist
constitutive androstane receptor agonists
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor
An EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of trypanothione-disulfide reductase (EC 1.8.1.12).
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitors
N(1),N(8)-bis(glutathionyl)spermidine reductase inhibitor
N(1),N(8)-bis(glutathionyl)spermidine reductase inhibitors
NADPH2:trypanothione oxidoreductase inhibitor
NADPH2:trypanothione oxidoreductase inhibitors
NADPH:trypanothione oxidoreductase inhibitor
NADPH:trypanothione oxidoreductase inhibitors
trypanothione-disulfide reductase (EC 1.8.1.12) inhibitor
trypanothione-disulfide reductase (EC 1.8.1.12) inhibitors
trypanothione:NADP(+) oxidoreductase inhibitor
trypanothione:NADP(+) oxidoreductase inhibitors
EC 1.1.1.188 (prostaglandin-F synthase) inhibitor
(5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP(+) 11-oxidoreductase inhibitor
(5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP(+) 11-oxidoreductase inhibitors
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of prostaglandin-F synthase (EC 1.1.1.188).
EC 1.1.1.188 (prostaglandin-F synthase) inhibitors
NADPH-dependent prostaglandin D2 11-keto reductase inhibitor
NADPH-dependent prostaglandin D2 11-keto reductase inhibitors
prostaglandin 11-keto reductase inhibitor
prostaglandin 11-keto reductase inhibitors
prostaglandin 11-ketoreductase inhibitor
prostaglandin 11-ketoreductase inhibitors
prostaglandin D2-ketoreductase inhibitor
prostaglandin D2-ketoreductase inhibitors
prostaglandin-D2 11-reductase inhibitors
reductase, 15-hydroxy-11-oxoprostaglandin inhibitor
reductase, 15-hydroxy-11-oxoprostaglandin inhibitors
synthetase, prostaglandin F2alpha inhibitor
synthetase, prostaglandin F2alpha inhibitors
EC 1.1.1.25 (shikimate dehydrogenase) inhibitor
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of shikimate dehydrogenase (EC 1.1.1.25).
EC 1.1.1.25 (shikimate dehydrogenase) inhibitors
shikimate dehydrogenase (EC 1.1.1.25) inhibitor
shikimate dehydrogenase (EC 1.1.1.25) inhibitors
shikimate:NADP(+) 3-oxidoreductase inhibitor
shikimate:NADP(+) 3-oxidoreductase inhibitors
shikimate:NADP(+) 5-oxidoreductase inhibitor
shikimate:NADP(+) 5-oxidoreductase inhibitors
shikimate:NADP(+) oxidoreductase inhibitor
shikimate:NADP(+) oxidoreductase inhibitors
An agonist that binds to and activates bradykinin receptors
A bradykinin agonist that binds to and activates bradykinin B2 receptors.
Any product obtained as a result of thermally induced non-enzymatic degradation.
Any thermal degradation product obtained as a result of a chemical reaction between an amino acid and a reducing sugar (Maillard reaction, a non-enzymatic browning procedure that usually imparts flavour to starch-based food products).
A phsychotropic drug that improves wakefulness and alertness, and reduces tiredness, drowsiness, and the need for sleep. Eugeroics are relatively non-addictive and are used in the treatment of narcolepsy and other sleep disorders.
A diuretic that acts on the ascending loop of Henle in the kidney.
EC 1.1.1.267 (1-deoxy-D-xylulose-5-phosphate reductoisomerase) inhibitor
1-deoxy-D-xylulose-5-phosphate isomeroreductase inhibitor
1-deoxy-D-xylulose-5-phosphate isomeroreductase inhibitors
1-deoxy-D-xylulose-5-phosphate reductoisomerase (EC 1.1.1.267) inhibitor
1-deoxy-D-xylulose-5-phosphate reductoisomerase (EC 1.1.1.267) inhibitors
1-deoxy-D-xylulose-5-phosphate reductoisomerase inhibitor
1-deoxy-D-xylulose-5-phosphate reductoisomerase inhibitors
1-deoxyxylulose-5-phosphate reductoisomerase inhibitor
1-deoxyxylulose-5-phosphate reductoisomerase inhibitors
2-C-methyl-D-erythritol-4-phosphate:NADP(+) oxidoreductase (isomerising) inhibitor
2-C-methyl-D-erythritol-4-phosphate:NADP(+) oxidoreductase (isomerising) inhibitors
2-C-methyl-D-erythritol-4-phosphate:NADP(+) oxidoreductase (isomerizing) inhibitor
2-C-methyl-D-erythritol-4-phosphate:NADP(+) oxidoreductase (isomerizing) inhibitors
2C-methyl-D-erythritol-4-phosphate (MEP) synthase inhibitor
2C-methyl-D-erythritol-4-phosphate (MEP) synthase inhibitors
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of 1-deoxy-D-xylulose-5-phosphate reductoisomerase (EC 1.1.1.267).
EC 1.1.1.267 (1-deoxy-D-xylulose-5-phosphate reductoisomerase) inhibitors
EC 4.3.1.3 (histidine ammonia-lyase) inhibitor
An EC 4.3.1.* (ammonia-lyase) inhibitor that interferes with the action of histidine ammonia-lyase (EC 4.3.1.3).
EC 4.3.1.3 (histidine ammonia-lyase) inhibitors
L-histidine ammonia-lyase (urocanate-forming) inhibitor
L-histidine ammonia-lyase (urocanate-forming) inhibitors
histidine ammonia-lyase (EC 4.3.1.3) inhibitor
histidine ammonia-lyase (EC 4.3.1.3) inhibitors
Any EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes with the action of any omega-peptidase (EC 3.4.19.*).
EC 3.4.19.* (omega-peptidase) inhibitors
omega-peptidase (EC 3.4.19.*) inhibitors
EC 3.4.19.3 (pyroglutamyl-peptidase I) inhibitor
An EC 3.4.19.* (omega-peptidase) inhibitor that interferes with the action of pyroglutamyl-peptidase I (EC 3.4.19.3).
EC 3.4.19.3 (pyroglutamyl-peptidase I) inhibitors
L-pyroglutamyl peptide hydrolase inhibitor
L-pyroglutamyl peptide hydrolase inhibitors
L-pyrrolidonecarboxylate peptidase inhibitor
L-pyrrolidonecarboxylate peptidase inhibitors
pyroglutamyl-peptidase I (EC 3.4.19.3) inhibitor
pyroglutamyl-peptidase I (EC 3.4.19.3) inhibitors
pyrrolidone-carboxyl peptidase inhibitor
pyrrolidone-carboxyl peptidase inhibitors
pyrrolidonecarboxylyl peptidase inhibitor
pyrrolidonecarboxylyl peptidase inhibitors
pyrrolidonyl peptidase inhibitors5-oxoprolyl-peptidase inhibitor
A drug used to relieve nasal congestion in the upper respiratory tract.
An EC 3.4.24.* (metalloendopeptidase) inhibitor that inhibits the action of meprin A (EC 3.4.24.18).
N-benzoyl-L-tyrosyl-p-aminobenzoic acid hydrolase inhibitor
N-benzoyl-L-tyrosyl-p-aminobenzoic acid hydrolase inhibitors
Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
EC 3.6.3.1 (phospholipid-translocating ATPase) inhibitor
ATP phosphohydrolase (phospholipid-flipping) inhibitor
ATP phosphohydrolase (phospholipid-flipping) inhibitors
An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of phospholipid-translocating ATPase (EC 3.6.3.1).
EC 3.6.3.1 (phospholipid-translocating ATPase) inhibitors
aminophospholipid-transporting ATPase inhibitor
aminophospholipid-transporting ATPase inhibitors
phospholipid-translocating ATPase (EC 3.6.3.1) inhibitor
phospholipid-translocating ATPase (EC 3.6.3.1) inhibitors
phospholipid-translocating ATPase inhibitor
phospholipid-translocating ATPase inhibitors
phospholipid-transporting ATPase inhibitor
phospholipid-transporting ATPase inhibitors
EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor
ATP phosphohydrolase (steroid-exporting) inhibitor
ATP phosphohydrolase (steroid-exporting) inhibitors
ATP phosphohydrolase (xenobiotic-exporting) inhibitor
ATP phosphohydrolase (xenobiotic-exporting) inhibitors
An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of xenobiotic-transporting ATPase (EC 3.6.3.44).
EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitors
pleiotropic-drug-resistance protein inhibitor
pleiotropic-drug-resistance protein inhibitors
xenobiotic-transporting ATPase (EC 3.6.3.44) inhibitor
xenobiotic-transporting ATPase (EC 3.6.3.44) inhibitors
xenobiotic-transporting ATPase inhibitor
xenobiotic-transporting ATPase inhibitors
Any inhibitor of the trasporter protein ATP/ADP translocase.
EC 3.1.4.53 (3',5'-cyclic-AMP phosphodiesterase) inhibitor
3',5'-cyclic-AMP 5'-nucleotidohydrolase inhibitor
3',5'-cyclic-AMP 5'-nucleotidohydrolase inhibitors
3',5'-cyclic-AMP phosphodiesterase (EC 3.1.4.53) inhibitor
3',5'-cyclic-AMP phosphodiesterase (EC 3.1.4.53) inhibitors
3',5'-cyclic-AMP phosphodiesterase inhibitor
3',5'-cyclic-AMP phosphodiesterase inhibitors
An EC 3.1.4.* (phosphoric diester hydrolase) inhibitor that interferes with the action of a 3',5'-cyclic-AMP phosphodiesterase (EC 3.1.4.53).
EC 3.1.4.53 (3',5'-cyclic-AMP phosphodiesterase) inhibitors
cAMP-specific phosphodiesterase inhibitor
cAMP-specific phosphodiesterase inhibitors
EC 1.2.1.88 (L-glutamate gamma-semialdehyde dehydrogenase) inhibitor
1-pyrroline-5-carboxylate dehydrogenase inhibitor
1-pyrroline-5-carboxylate dehydrogenase inhibitors
1-pyrroline-5-carboxylate:NAD(+) oxidoreductase inhibitor
1-pyrroline-5-carboxylate:NAD(+) oxidoreductase inhibitors
An EC 1.2.1.* (oxidoreductase acting on donor aldehyde/oxo group with NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88).
Delta(1)-pyrroline-5-carboxylate dehydrogenase inhibitor
Delta(1)-pyrroline-5-carboxylate dehydrogenase inhibitors
Delta(1)-pyrroline-5-carboxylic acid dehydrogenase inhibitor
Delta(1)-pyrroline-5-carboxylic acid dehydrogenase inhibitors
EC 1.2.1.88 (L-glutamate gamma-semialdehyde dehydrogenase) inhibitors
L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88) inhibitor
L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88) inhibitors
L-glutamate gamma-semialdehyde dehydrogenase inhibitor
L-glutamate gamma-semialdehyde dehydrogenase inhibitors
L-glutamate gamma-semialdehyde:NAD(+) oxidoreductase inhibitor
L-glutamate gamma-semialdehyde:NAD(+) oxidoreductase inhibitors
L-pyrroline-5-carboxylate-NAD(+) oxidoreductase inhibitor
L-pyrroline-5-carboxylate-NAD(+) oxidoreductase inhibitors
pyrroline-5-carboxylate dehydrogenase inhibitor
pyrroline-5-carboxylate dehydrogenase inhibitors
pyrroline-5-carboxylic acid dehydrogenase inhibitor
pyrroline-5-carboxylic acid dehydrogenase inhibitors
A sulfonamide that is sulfanilamide in which the sulfonamide nitrogen is substituted by a 1-phenyl-1H-pyrazol-5-yl group. It is a selective inhibitor of cytochrome P450 (CYP) 2C9 isozyme, and antibacterial agent.
EC 1.14.13.181 (13-deoxydaunorubicin hydroxylase) inhibitor
13-deoxydaunorubicin hydroxylase (EC 1.14.13.181) inhibitor
13-deoxydaunorubicin hydroxylase (EC 1.14.13.181) inhibitors
13-deoxydaunorubicin hydroxylase inhibitor
13-deoxydaunorubicin hydroxylase inhibitors
13-deoxydaunorubicin,NADPH:oxygen oxidoreductase (13-hydroxylating) inhibitor
13-deoxydaunorubicin,NADPH:oxygen oxidoreductase (13-hydroxylating) inhibitors
An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of 13-deoxydaunorubicin hydroxylase (EC 1.14.13.181).
EC 1.14.13.181 (13-deoxydaunorubicin hydroxylase) inhibitors
EC 1.14.13.67 (quinine 3-monooxygenase) inhibitor
An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of quinine 3-monooxygenase (EC 1.14.13.67).
EC 1.14.13.67 (quinine 3-monooxygenase) inhibitors
quinine 3-monooxygenase (EC 1.14.13.67) inhibitor
quinine 3-monooxygenase (EC 1.14.13.67) inhibitors
quinine,NADPH:oxygen oxidoreductase inhibitor
quinine,NADPH:oxygen oxidoreductase inhibitors
Any environmental contaminant that is resistant to environmental degradation through photolytic, biological or chemical processes. Such substances can have significant impact on health and the environment, as they persist in the environment, bioaccumulate in animal tissue and so biomagnify in food chains.
EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor
2,3-diaminopropanoate ammonia-lyase (adding H2O; pyruvate-forming) inhibitor
2,3-diaminopropanoate ammonia-lyase (adding H2O; pyruvate-forming) inhibitors
2,3-diaminopropanoate ammonia-lyase (adding water; pyruvate-forming) inhibitor
2,3-diaminopropanoate ammonia-lyase (adding water; pyruvate-forming) inhibitors
2,3-diaminopropanoate ammonia-lyase inhibitor
2,3-diaminopropanoate ammonia-lyase inhibitors
2,3-diaminopropionate ammonia-lyase inhibitor
2,3-diaminopropionate ammonia-lyase inhibitors
An EC 4.3.1.* (ammonia-lyase) inhibitor that interferes with the action of diaminopropionate ammonia-lyase (EC 4.3.1.15).
EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitors
alpha,beta-diaminopropionate ammonia-lyase inhibitor
alpha,beta-diaminopropionate ammonia-lyase inhibitors
diaminopropionate ammonia-lyase (EC 4.3.1.15) inhibitor
diaminopropionate ammonia-lyase (EC 4.3.1.15) inhibitors
diaminopropionate ammonia-lyase inhibitor
diaminopropionate ammonia-lyase inhibitors
EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor
An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of EC 1.14.13.70 (sterol 14alpha-demethylase).
EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitors
sterol,NADPH:oxygen oxidoreductase (14-methyl cleaving) inhibitor
sterol,NADPH:oxygen oxidoreductase (14-methyl cleaving) inhibitors
An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of amidase (EC 3.5.1.4).
EC 6.1.1.4 (leucine--tRNA ligase) inhibitor
An EC 6.1.1.* (ligases forming aminoacyl tRNA and related compounds) inhibitor that inhibits the action of leucine--tRNA synthetase (EC 6.1.1.4).
EC 6.1.1.4 (leucine--tRNA ligase) inhibitors
L-leucine:tRNA(Leu) ligase (AMP-forming) inhibitor
L-leucine:tRNA(Leu) ligase (AMP-forming) inhibitors
leucyl-transfer RNA synthetase inhibitor
leucyl-transfer RNA synthetase inhibitors
leucyl-transfer ribonucleate synthetase inhibitor
leucyl-transfer ribonucleate synthetase inhibitors
leucyl-transfer ribonucleic acid synthetase inhibitor
leucyl-transfer ribonucleic acid synthetase inhibitors
A food additive that is used to make or keep fruit or vegetable tissues firm and crisp. or which interacts with gelling agents such as pectin to produce or strengthen a gel.
An antioxidant that used as a food additives to help guard against food deterioration.
A food preservative that acts by chelating with metal cations (particularly those of copper, iron and nickel) that catalyse the oxidation of fats in food.
A substance added to powdered or granulated materials in order to prevent the formation of lumps and so facilitate its packaging or transport.
An anticaking agent that is used to reduced the tendency of particles of food to adhere to one another.
A food additive that is used to preserve the structure of food.
A compound that is used to keep a substance moist.
A humectant that is used as a food additive to prevent foodstuffs from drying out.
A food additive that is used to increase the viscosity of foodstuffs.
A food additive which liberates gas so as to increase the volume of a dough or batter, resulting in a lighter and softer finished product.
A food additive that is applied to the external surface or a food in order to give a smooth shiny appearance and/or to provide a protective coating to foodstuffs.
A substance that reduces and hinders the formation of foam in solutions and other liquids during their industrial or laboratory processing.
A food additive that is a (generally inert) gas which is used to envelop foodstuffs during packing and so protect them from unwanted chemical reactions such as food spoilage or oxidation during subsequent transport and storage. The term includes propellant gases, used to expel foods from a container.
A food additive that is used for the purpose of decolourising food.
A food additive that contributes to the bulk of a food without significantly contributing to its available energy value.
A food additive that intensifies, retains or stabilises the colour of a food.
A food additive that makes it possible to form or maintain a uniform dispersion of a gaseous phase in a liquid or solid phase.
Wiskott-Aldrich syndrome protein inhibitor
Any inhibitor of Wiskott-Aldrich syndrome protein.
Wiskott-Aldrich syndrome protein inhibitors
A food additive that enhances the texture of a foodstuff by gel formation.
A propellant that is used to expel foods from an aerosol container.
EC 4.1.1.50 (adenosylmethionine decarboxylase) inhibitor
An EC 4.1.1.* (carboxy-lyase) inhibitor that interferes with the action of adenosylmethionine decarboxylase (EC 4.1.1.50).
EC 4.1.1.50 (adenosylmethionine decarboxylase) inhibitors
S-adenosyl-L-methionine carboxy-lyase [(5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium-salt-forming] inhibitor
S-adenosyl-L-methionine carboxy-lyase [(5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium-salt-forming] inhibitors
S-adenosyl-L-methionine carboxy-lyase [S-adenosyl 3-(methylthio)propylamine-forming] inhibitor
S-adenosyl-L-methionine carboxy-lyase [S-adenosyl 3-(methylthio)propylamine-forming] inhibitors
S-adenosyl-L-methionine carboxy-lyase inhibitor
S-adenosyl-L-methionine carboxy-lyase inhibitors
S-adenosyl-L-methionine decarboxylase inhibitor
S-adenosyl-L-methionine decarboxylase inhibitors
S-adenosylmethionine decarboxylase inhibitor
S-adenosylmethionine decarboxylase inhibitors
A substance that inhibits any of the Wnt signalling pathway, a group of signal transduction pathways made of proteins that pass signals from outside of a cell through cell surface receptors to the inside of the cell.
A food additive that is used to reduce or prevent foaming during the processing or manufacture of foodstuffs.
A food additive that is used to dilute, disperse or dissolve a food additive or nutrient without altering its function. Carriers are used to facilitate the handling or use of the food additive or nutrient.
Any small molecule that mimics the action of an enzyme.
A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a hydroxy group at position 3 and phenyl group at position 5.
An antagonist which acts by inhibiting the action of vitamin B1
A physiological role played by any substance that is distributed in foodstuffs. It includes materials derived from plants or animals, such as vitamins or minerals, as well as environmental contaminants.
Any minor or unwanted substance introduced into the environment that can have undesired effects.
Any unwanted chemical in food. The term includes agrochemicals and industrial chemicals that may contaminate foodstuffs during their production, transportation or storage.
Any metabolite that is produced during a metabolite reaction in lichens (composite organisms consisting of a fungus and a photosynthetic partner co-existing in a symbiotic relationship).
ATP:D-hexose 6-phosphotransferase inhibitor
ATP:D-hexose 6-phosphotransferase inhibitors
An EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor that interferes with the action of hexokinase, EC 2.7.1.1, an enzyme that phosphorylates hexoses forming hexose phosphate.
glucose ATP phosphotransferase inhibitor
glucose ATP phosphotransferase inhibitors
hexokinase type IV glucokinase inhibitor
hexokinase type IV glucokinase inhibitors
EC 3.1.1.5 (lysophospholipase) inhibitor
2-lysophosphatidylcholine acylhydrolase inhibitor
2-lysophosphatidylcholine acylhydrolase inhibitors
An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of the enzyme lysophospholipase (EC 3.1.1.5), which catalyses the release of fatty acids from lysophospholipids.
EC 3.1.1.5 (lysophospholipase) inhibitors
lysophosphatidylcholine hydrolase inhibitor
lysophosphatidylcholine hydrolase inhibitors
lysophospholipase (EC 3.1.1.5) inhibitor
lysophospholipase (EC 3.1.1.5) inhibitors
lysophospholipase transacylase inhibitor
lysophospholipase transacylase inhibitors
EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor
An EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of acyl-CoA dehydrogenase (NADP(+)), EC 1.3.1.8.
EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitors
acyl-CoA dehydrogenase (NADP(+)) (EC 1.3.1.8) inhibitor
acyl-CoA dehydrogenase (NADP(+)) (EC 1.3.1.8) inhibitors
acyl-CoA dehydrogenase (NADP(+)) inhibitor
acyl-CoA dehydrogenase (NADP(+)) inhibitors
acyl-CoA:NADP(+) 2-oxidoreductase inhibitor
acyl-CoA:NADP(+) 2-oxidoreductase inhibitors
crotonyl coenzyme A reductase inhibitors
dehydrogenase, acyl coenzyme A (nicotinamide adenine dinucleotide phosphate) inhibitor
dehydrogenase, acyl coenzyme A (nicotinamide adenine dinucleotide phosphate) inhibitors
EC 2.5.1.7 (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) inhibitor
An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC 2.5.1.7).
EC 2.5.1.7 (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) inhibitors
UDP-N-acetylglucosamine 1-carboxyvinyl-transferase inhibitor
UDP-N-acetylglucosamine 1-carboxyvinyl-transferase inhibitors
UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC 2.5.1.7) inhibitor
UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC 2.5.1.7) inhibitors
UDP-N-acetylglucosamine 1-carboxyvinyltransferase inhibitor
UDP-N-acetylglucosamine 1-carboxyvinyltransferase inhibitors
UDP-N-acetylglucosamine enoylpyruvyltransferase inhibitor
UDP-N-acetylglucosamine enoylpyruvyltransferase inhibitors
phosphoenolpyruvate-UDP-acetylglucosamine-3-enolpyruvyltransferase inhibitor
phosphoenolpyruvate-UDP-acetylglucosamine-3-enolpyruvyltransferase inhibitors
phosphoenolpyruvate:UDP-2-acetamido-2-deoxy-D-glucose 2-enoyl-1-carboxyethyltransferase inhibitor
phosphoenolpyruvate:UDP-2-acetamido-2-deoxy-D-glucose 2-enoyl-1-carboxyethyltransferase inhibitors
phosphoenolpyruvate:UDP-N-acetyl-D-glucosamine 1-carboxyvinyltransferase inhibitor
phosphoenolpyruvate:UDP-N-acetyl-D-glucosamine 1-carboxyvinyltransferase inhibitors
phosphoenolpyruvate:UDP-N-acetyl-alpha-D-glucosamine 1-carboxyvinyltransferase inhibitor
phosphoenolpyruvate:UDP-N-acetyl-alpha-D-glucosamine 1-carboxyvinyltransferase inhibitors
phosphoenolpyruvate:uridine diphosphate N-acetylglucosamine enolpyruvyltransferase inhibitor
phosphoenolpyruvate:uridine diphosphate N-acetylglucosamine enolpyruvyltransferase inhibitors
phosphoenolpyruvate:uridine-5'-diphospho-N-acetyl-2-amino-2-deoxyglucose 3-enolpyruvyltransferase inhibitor
phosphoenolpyruvate:uridine-5'-diphospho-N-acetyl-2-amino-2-deoxyglucose 3-enolpyruvyltransferase inhibitors
phosphopyruvate-uridine diphosphoacetylglucosamine pyruvatetransferase inhibitor
phosphopyruvate-uridine diphosphoacetylglucosamine pyruvatetransferase inhibitors
pyruvate-UDP-acetylglucosamine transferase inhibitor
pyruvate-UDP-acetylglucosamine transferase inhibitors
pyruvate-uridine diphospho-N-acetyl-glucosamine transferase inhibitor
pyruvate-uridine diphospho-N-acetyl-glucosamine transferase inhibitors
pyruvate-uridine diphospho-N-acetylglucosamine transferase inhibitor
pyruvate-uridine diphospho-N-acetylglucosamine transferase inhibitors
pyruvic-uridine diphospho-N-acetylglucosaminyltransferase inhibitor
pyruvic-uridine diphospho-N-acetylglucosaminyltransferase inhibitors
EC 3.5.4.1 (cytosine deaminase) inhibitor
An EC 3.5.4.* (non-peptide cyclic amidine C-N hydrolase) inhibitor that interferes with the action of cytosine deaminase (EC 3.5.4.1).
EC 3.5.4.1 (cytosine deaminase) inhibitors
cytosine deaminase (EC 3.5.4.1) inhibitor
cytosine deaminase (EC 3.5.4.1) inhibitors
EC 5.1.2.* (racemases acting on hydroxy acids and derivatives) inhibitor
An EC 5.1.* (racemase/epimerase) inhibitor that interferes with the action of any such enzyme acting on hydroxy acids and their derivatives (EC 5.1.2.*).
EC 5.1.2.* (racemases acting on hydroxy acids and derivatives) inhibitors
inhibitor of racemases acting on hydroxy acids and derivatives
inhibitor of racemases acting on hydroxy acids and derivatives (EC 5.1.2.*)
inhibitors of racemases acting on hydroxy acids and derivatives
inhibitors of racemases acting on hydroxy acids and derivatives (EC 5.1.2.*)
EC 5.1.3.* (racemases acting on carbohydrates and derivatives) inhibitor
An EC 5.1.* (racemase/epimerase) inhibitor that interferes with the action of any such enzyme acting on carbohydrates and their derivatives (EC 5.1.3.*).
EC 5.1.3.* (racemases acting on carbohydrates and derivatives) inhibitors
inhibitor of racemases acting on carbohydrates and derivatives
inhibitor of racemases acting on carbohydrates and derivatives (EC 5.1.3.*)
inhibitors of racemases acting on carbohydrates and derivatives
inhibitors of racemases acting on carbohydrates and derivatives (EC 5.1.3.*)
EC 5.1.99.* (racemases acting on other compounds) inhibitor
An EC 5.1.* (racemase/epimerase) inhibitor that interferes with the action of any such enzyme acting compounds other than amino acids and their derivatives, hydroxy acids and their derivatives, or carbohydrates and their derivatives (EC 5.1.99.*).
EC 5.1.99.* (racemases acting on other compounds) inhibitors
inhibitor of racemases acting on other compounds (EC 5.1.99.*)
inhibitors of racemases acting on other compounds (EC 5.1.99.*)
EC 5.1.3.2 (UDP-glucose 4-epimerase) inhibitor
An EC 5.1.3.* (racemases acting on carbohydrates and derivatives) inhibitor that interferes with the action of UDP-glucose 4-epimerase (EC 5.1.3.2).
EC 5.1.3.2 (UDP-glucose 4-epimerase) inhibitors
UDP-alpha-D-glucose 4-epimerase inhibitor
UDP-alpha-D-glucose 4-epimerase inhibitors
UDP-glucose 4-epimerase (EC 5.1.3.2) inhibitor
UDP-glucose 4-epimerase (EC 5.1.3.2) inhibitors
uridine diphosphate galactose 4-epimerase inhibitor
uridine diphosphate galactose 4-epimerase inhibitors
uridine diphosphate glucose 4-epimerase inhibitor
uridine diphosphate glucose 4-epimerase inhibitors
uridine diphospho-galactose-4-epimerase inhibitor
uridine diphospho-galactose-4-epimerase inhibitors
uridine diphosphoglucose 4-epimerase inhibitor
uridine diphosphoglucose 4-epimerase inhibitors
uridine diphosphoglucose epimerase inhibitor
uridine diphosphoglucose epimerase inhibitors
A substance used in a thermodynamic heat pump cycle or refrigeration cycle that undergoes a phase change from a gas to a liquid and back. Refrigerants are used in air-conditioning systems and freezers or refrigerators and are assigned a "R" number (by ASHRAE - formerly the American Society of Heating, Refrigerating and Air Conditioning Engineers), which is determined systematically according to their molecular structure.
Any EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that inhibits the action of carboxylesterase (EC 3.1.1.1 ).
EC 3.1.1.1 (carboxylesterase) inhibitors
A toxin used by animals and injected into their victims by a bite or sting.
A protein kinase agonist that selectively binds to and activates a protein kinase A receptor
Any agonist of one or more of the isoforms of adenylate cyclase (EC 4.6.1.1).
Any compound that causes severe skin, eye and mucosal pain and irritation.
EC 2.7.11.31 {[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase} inhibitor
3-hydroxy-3-methylglutaryl coenzyme A reductase kinase inhibitor
3-hydroxy-3-methylglutaryl coenzyme A reductase kinase inhibitors
3-hydroxy-3-methylglutaryl-CoA reductase kinase inhibitor
3-hydroxy-3-methylglutaryl-CoA reductase kinase inhibitors
ATP:[hydroxymethylglutaryl-CoA reductase (NADPH)] phosphotransferase inhibitor
ATP:[hydroxymethylglutaryl-CoA reductase (NADPH)] phosphotransferase inhibitors
An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of any [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase (EC 2.7.11.31).
EC 2.7.11.31 ([hydroxymethylglutaryl-CoA reductase (NADPH)] kinase) inhibitor
EC 2.7.11.31 ([hydroxymethylglutaryl-CoA reductase (NADPH)] kinase) inhibitors
EC 2.7.11.31 {[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase} inhibitors
[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase inhibitor
[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase inhibitors
[hydroxymethylglutaryl-CoA reductase (NADPH2)] kinase inhibitor
[hydroxymethylglutaryl-CoA reductase (NADPH2)] kinase inhibitors
beta-hydroxy-beta-methylglutaryl-CoA reductase kinase inhibitor
beta-hydroxy-beta-methylglutaryl-CoA reductase kinase inhibitors
hydroxymethylglutaryl coenzyme A reductase kinase (phosphorylating) inhibitor
hydroxymethylglutaryl coenzyme A reductase kinase (phosphorylating) inhibitors
hydroxymethylglutaryl coenzyme A reductase kinase inhibitor
hydroxymethylglutaryl coenzyme A reductase kinase inhibitors
hydroxymethylglutaryl-CoA reductase kinase inhibitor
hydroxymethylglutaryl-CoA reductase kinase inhibitors
bone morphogenetic protein receptor antagonist
An antagonist at the bone morphogenetic protein receptor.
bone morphogenetic protein receptor inhibitors
Any metabolite produced by all living cells.
EC 4.6.1.2 (guanylate cyclase) inhibitor
An EC 4.6.* (P-O lyase) inhibitor that interferes with the action of enzyme guanylate cyclase (EC 4.6.1.2).
EC 4.6.1.2 (guanylate cyclase) inhibitors
GTP diphosphate-lyase (cyclizing) inhibitor
GTP diphosphate-lyase (cyclizing) inhibitors
GTP diphosphate-lyase (cyclizing; 3',5'-cyclic-GMP-forming) inhibitor
GTP diphosphate-lyase (cyclizing; 3',5'-cyclic-GMP-forming) inhibitors
tropomyosin-related kinase B receptor antagonist
An antagonist that binds to and deactivates the tropomyosin-related kinase B (TrkB) receptor, the main signaling receptor of the neurotrophin brain-derived neurotrophic factor (BDNF).
tropomyosin-related kinase B receptor antagonists
EC 2.3.1.97 (glycylpeptide N-tetradecanoyltransferase) inhibitor
An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of glycylpeptide N-tetradecanoyltransferase (EC 2.3.1.97).
EC 2.3.1.97 (glycylpeptide N-tetradecanoyltransferase) inhibitors
myristoyl-CoA-protein N-myristoyltransferase inhibitor
myristoyl-CoA-protein N-myristoyltransferase inhibitors
myristoyl-coenzyme A:protein N-myristoyl transferase inhibitor
myristoyl-coenzyme A:protein N-myristoyl transferase inhibitors
peptide N-myristoyltransferase inhibitor
peptide N-myristoyltransferase inhibitors
protein N-myristoyltransferase inhibitor
protein N-myristoyltransferase inhibitors
tetradecanoyl-CoA:glycylpeptide N-tetradecanoyltransferase inhibitor
tetradecanoyl-CoA:glycylpeptide N-tetradecanoyltransferase inhibitors
EC 1.3.1.72 (Delta(24)-sterol reductase) inhibitor
An EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of Delta(24)-sterol reductase (EC 1.3.1.72).
Delta(24)-sterol reductase (EC 1.3.1.72) inhibitor
Delta(24)-sterol reductase (EC 1.3.1.72) inhibitors
EC 1.3.1.72 (Delta(24)-sterol reductase) inhibitors
EC 2.5.1.6 (methionine adenosyltransferase) inhibitor
ATP-methionine adenosyltransferase inhibitor
ATP-methionine adenosyltransferase inhibitors
ATP:L-methionine S-adenosyltransferase inhibitor
ATP:L-methionine S-adenosyltransferase inhibitors
An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of methionine adenosyltransferase (EC 2.5.1.6).
EC 2.5.1.6 (methionine adenosyltransferase) inhibitors
S-adenosyl-L-methionine synthetase inhibitor
S-adenosyl-L-methionine synthetase inhibitors
S-adenosylmethionine synthase inhibitors
S-adenosylmethionine synthetase inhibitor
S-adenosylmethionine synthetase inhibitors
adenosylmethionine synthetase inhibitors
methionine S-adenosyltransferase inhibitor
methionine S-adenosyltransferase inhibitors
EC 2.7.1.91 (sphingosine kinase) inhibitor
ATP:sphinganine 1-phosphotransferase inhibitor
ATP:sphinganine 1-phosphotransferase inhibitors
An EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor that interferes with the action of sphinganine kinase (EC 2.7.1.91).
EC 2.7.1.91 (sphinganine kinase) inhibitor
EC 2.7.1.91 (sphinganine kinase) inhibitors
EC 2.7.1.91 (sphingosine kinase) inhibitors
dihydrosphingosine kinase (phosphorylating) inhibitor
dihydrosphingosine kinase (phosphorylating) inhibitors
sphingosine kinase (phosphorylating) inhibitor
sphingosine kinase (phosphorylating) inhibitors
EC 2.7.11.18 (myosin-light-chain kinase) inhibitor
ATP:[myosin-light-chain] O-phosphotransferase inhibitor
ATP:[myosin-light-chain] O-phosphotransferase inhibitors
ATP:myosin-light-chain O-phosphotransferase inhibitor
ATP:myosin-light-chain O-phosphotransferase inhibitors
An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of myosin-light-chain kinase (EC 2.7.11.18).
EC 2.7.11.18 (myosin-light-chain kinase) inhibitors
calcium/calmodulin-dependent myosin light chain kinase inhibitor
calcium/calmodulin-dependent myosin light chain kinase inhibitors
myosin light chain protein kinase inhibitor
myosin light chain protein kinase inhibitors
myosin light-chain kinase (phosphorylating) inhibitor
myosin light-chain kinase (phosphorylating) inhibitors
myosin-light-chain kinase (EC 2.7.11.18) inhibitor
myosin-light-chain kinase (EC 2.7.11.18) inhibitors
smooth-muscle-myosin-light-chain kinase inhibitor
smooth-muscle-myosin-light-chain kinase inhibitors
An animal metabolite produced by any member of the phylum Nematoda.
A nematode metabolite produced by Caenorhabditis elegans.
Any compound that affects the dimerisation of the protein survivin.
EC 3.6.1.* (hydrolases acting on acid anhydrides in P-containing anhydrides) inhibitor
Any EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor that interferes with the action of any such enzyme acting on phosphorus-containing anhydrides.
EC 3.6.1.* (hydrolases acting on acid anhydrides in P-containing anhydrides) inhibitors
EC 3.6.1.* (hydrolases acting on acid anhydrides in phosphorus-containing anhydrides) inhibitor
EC 3.6.1.* (hydrolases acting on acid anhydrides in phosphorus-containing anhydrides) inhibitors
hydrolases acting on acid anhydrides in P-containing anhydrides (EC 3.6.1.*) inhibitor
hydrolases acting on acid anhydrides in P-containing anhydrides (EC 3.6.1.*) inhibitors
hydrolases acting on acid anhydrides in phosphorus-containing anhydrides (EC 3.6.1.*) inhibitor
hydrolases acting on acid anhydrides in phosphorus-containing anhydrides (EC 3.6.1.*) inhibitors
EC 3.6.1.3 (adenosinetriphosphatase) inhibitor
An EC 3.6.1.* (hydrolases acting on acid anhydrides in P-containing anhydrides) inhibitor that interferes with the action of adenosinetriphosphatase (EC 3.6.1.3).
EC 3.6.1.3 (adenosinetriphosphatase) inhibitors
adenosinetriphosphatase (EC 3.6.1.3) inhibitor
adenosinetriphosphatase (EC 3.6.1.3) inhibitors
complex V (mitochondrial electron transport) inhibitor
complex V (mitochondrial electron transport) inhibitors
Any prokaryotic metabolite produced during a metabolic reaction in single-celled microorganisms, archaea.
An agonist that binds to and activates melatonin receptors.
A calpain inhibitor that interferes with the action of calpain-1 (EC 3.4.22.52).
calcium-activated neutral protease I inhibitor
calcium-activated neutral protease I inhibitors
Any compound that is used as an additive to increase the plasticity or fluidity of a substance, particularly but not exclusively to synthetic polymers.
A potassium channel modulator that opens the potassium channel.
95 kDa type IV collagenase/gelatinase inhibitor
95 kDa type IV collagenase/gelatinase inhibitors
An EC 3.4.24.* (metalloendopeptidase) inhibitor that interferes with the action of gelatinase B (EC 3.4.24.35).
type IV collagen metalloproteinase inhibitor
type IV collagen metalloproteinase inhibitors
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
ATP:protein phosphotransferase (MAPKK-activated) inhibitor
ATP:protein phosphotransferase (MAPKK-activated) inhibitors
An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of mitogen-activated protein kinase (EC 2.7.11.24).
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitors
extracellular signal-regulated kinase inhibitor
extracellular signal-regulated kinase inhibitors
microtubule-associated protein kinase inhibitor
microtubule-associated protein kinase inhibitors
mitogen-activated protein kinase (EC 2.7.11.24) inhibitor
mitogen-activated protein kinase (EC 2.7.11.24) inhibitors
mitogen-activated protein kinase inhibitor
mitogen-activated protein kinase inhibitors
p42 mitogen-activated protein kinase inhibitor
p42 mitogen-activated protein kinase inhibitors
stress-activated protein kinase inhibitor
stress-activated protein kinase inhibitors
EC 1.11.2.* (oxidoreductase with H2O2 as acceptor, incorporating 1 O atom into product) inhibitor
An EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitor that interferes with the action of any such enzyme using H2O2 as acceptor and incorporating one oxygen atom of the H2O2 into the product (EC 1.11.2.*).
EC 1.11.2.* (oxidoreductase with H2O2 as acceptor, incorporating 1 O atom into product) inhibitors
An EC 1.11.2.* (oxidoreductase with H2O2 as acceptor, incorporating 1 O atom into product) inhibitor that interferes with the action of myeloperoxidase (EC 1.11.2.2).
EC 1.11.2.2 (myeloperoxidase) inhibitors
chloride:hydrogen-peroxide oxidoreductase (hypochlorite-forming) inhibitor
chloride:hydrogen-peroxide oxidoreductase (hypochlorite-forming) inhibitors
myeloperoxidase (EC 1.11.2.2) inhibitors
Any compound that is added to manufactured materials to inhibit, suppress, or delay the production of flames and so prevent the spread of fire.
A benzodioxole that consists of piperidine bearing 1,3-benzodioxol-5-yloxy)methyl and 4-fluorophenyl substituents at positions 3 and 4 respectively; the (3S,4R)-diastereomer. Highly potent and selective 5-HT uptake inhibitor that binds with high affinity to the serotonin transporter (Ki = 0.05 nM). Ki values are 1.1, 350 and 1100 nM for inhibition of [3H]-5-HT, [3H]-l-NA and [3H]-DA uptake respectively. Displays minimal affinity for alpha1-, alpha2- or beta-adrenoceptors, 5-HT2A, 5-HT1A, D2 or H1 receptors at concentrations below 1000 nM, however displays weak affinity for muscarinic ACh receptors (Ki = 42 nM). Antidepressant and anxiolytic in vivo.
glycerophosphoinositol synthesis inhibitor
A pathway inhibitor that disrupts the synthesis of glycerophosphoinositol
glycerophosphoinositol synthesis inhibitors
EC 6.1.1.2 (tryptophan--tRNA ligase) inhibitor
An EC 6.1.1.* (ligases forming aminoacyl tRNA and related compounds) inhibitor that interferes with the action of any tryptophan--tRNA ligase (EC 6.1.1.2).
EC 6.1.1.2 (tryptophan--tRNA ligase) inhibitors
L-tryptophan-tRNA(Trp) ligase (AMP-forming) inhibitor
L-tryptophan-tRNA(Trp) ligase (AMP-forming) inhibitors
L-tryptophan:tRNA(Trp) ligase (AMP-forming) inhibitor
L-tryptophan:tRNA(Trp) ligase (AMP-forming) inhibitors
tryptophan--tRNA ligase (EC 6.1.1.2) inhibitor
tryptophan--tRNA ligase (EC 6.1.1.2) inhibitors
tryptophanyl ribonucleic synthetase inhibitor
tryptophanyl ribonucleic synthetase inhibitors
tryptophanyl-transfer RNA synthetase inhibitor
tryptophanyl-transfer RNA synthetase inhibitors
tryptophanyl-transfer ribonucleate synthetase inhibitor
tryptophanyl-transfer ribonucleate synthetase inhibitors
tryptophanyl-transfer ribonucleic acid synthetase inhibitor
tryptophanyl-transfer ribonucleic acid synthetase inhibitors
tryptophanyl-transfer ribonucleic synthetase inhibitor
tryptophanyl-transfer ribonucleic synthetase inhibitors
A member of the class of acetamides that is acetamide in which one of the hydrogens attached to the nitrogen is substituted by a 4-ethoxyphenyl group.
A chromophore that is a linear tetrapyrrolic prosthetic group covalently attached to a large soluble protein phytochrome. Light absorption by the phytochrome chromophore triggers photoconversion between two spectrally distinct forms of the photoreceptor: Pr, the red light absorbing form, and Pfr, the far-red light absorbing form.
Substances that are administered to farmed animals to improve productivity by promoting weight gain, increasing muscle mass, limiting fat deposition, reducing feed consumption, and reducing waste production.
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
ATP:cyclin phosphotransferase inhibitors
An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of cyclin-dependent kinase (EC 2.7.11.22).
Cdk-activating protein kinase inhibitors
EC 2.7.11.22 (cyclin-dependent kinase) inhibitors
cyclin-dependent protein kinase activating kinase inhibitor
cyclin-dependent protein kinase activating kinase inhibitors
EC 6.1.1.12 (aspartate--tRNA ligase) inhibitor
An EC 6.1.1.* (ligases forming aminoacyl tRNA and related compounds) inhibitor that specifically inhibits the action of aspartate--tRNA ligase (EC 6.1.1.12).
EC 6.1.1.12 (aspartate--tRNA ligase) inhibitors
L-aspartate:tRNA(Asp) ligase (AMP-forming) inhibitor
L-aspartate:tRNA(Asp) ligase (AMP-forming) inhibitors
aspartyl ribonucleate synthetase inhibitor
aspartyl ribonucleate synthetase inhibitors
aspartyl ribonucleic synthetase inhibitor
aspartyl ribonucleic synthetase inhibitors
aspartyl-transfer RNA synthetase inhibitor
aspartyl-transfer RNA synthetase inhibitors
aspartyl-transfer ribonucleic acid synthetase inhibitor
aspartyl-transfer ribonucleic acid synthetase inhibitors
A calpain inhibitor that interferes with the action of calpain-2 (EC 3.4.22.53).
calcium-activated neutral protease II inhibitor
calcium-activated neutral protease II inhibitors
An EC 3.4.22.* (cysteine endopeptidase) inhibitor that interferes with the action of calpain-3 (EC 3.4.22.54).
calcium-activated neutral proteinase 3 inhibitor
calcium-activated neutral proteinase 3 inhibitors
muscle-specific calcium-activated neutral protease 3 inhibitor
muscle-specific calcium-activated neutral protease 3 inhibitors
An EC 3.4.22.* (cysteine endopeptidase) inhibitor that interferes with the action of any calpain.
An antagonist that binds to and deactivates glucocorticoid receptors.
Metabolites produced by the gut microbiota or microorganisms (e.g. bacteria and fungi) that live in the digestive tracts of animals.
An EC 3.4.24.* (metalloendopeptidase) inhibitor that interferes with the action of neprilysin (EC 3.4.24.11).
CALLA (common acute lymphoblastic leukemia-associated) antigens inhibitor
CALLA (common acute lymphoblastic leukemia-associated) antigens inhibitors
acute lymphoblastic leukemia antigen inhibitor
acute lymphoblastic leukemia antigen inhibitors
common acute lymphoblastic leukemia antigen inhibitor
common acute lymphoblastic leukemia antigen inhibitors
common acute lymphoblastic leukemia-associated antigens inhibitor
common acute lymphoblastic leukemia-associated antigens inhibitors
kidney-brush-border neutral endopeptidase inhibitor
kidney-brush-border neutral endopeptidase inhibitors
kidney-brush-border neutral peptidase inhibitor
kidney-brush-border neutral peptidase inhibitors
kidney-brush-border neutral proteinase inhibitor
kidney-brush-border neutral proteinase inhibitors
membrane metalloendopeptidase inhibitors
EC 3.4.24.71 (endothelin-converting enzyme 1) inhibitor
An EC 3.4.24.* (metalloendopeptidase) inhibitor that interferes with the action of endothelin-converting enzyme 1 (EC 3.4.24.71).
EC 3.4.24.71 (endothelin-converting enzyme 1) inhibitors
endothelin-converting enzyme 1 (EC 3.4.24.71) inhibitor
endothelin-converting enzyme 1 (EC 3.4.24.71) inhibitors
endothelin-converting enzyme 1 inhibitor
endothelin-converting enzyme 1 inhibitors
EC 4.1.2.27 (sphinganine-1-phosphate aldolase) inhibitor
An EC 4.1.2.* (aldehyde-lyase) inhibitor that interferes with the action of sphinganine-1-phosphate aldolase (EC 4.1.2.27).
EC 4.1.2.27 (sphinganine-1-phosphate aldolase) inhibitors
dihydrosphingosine 1-phosphate aldolase inhibitor
dihydrosphingosine 1-phosphate aldolase inhibitors
sphinganine-1-phosphate alkanal-lyase inhibitor
sphinganine-1-phosphate alkanal-lyase inhibitors
sphinganine-1-phosphate lyase inhibitors
sphinganine-1-phosphate palmitaldehyde-lyase (phosphoethanolamine-forming) inhibitor
sphinganine-1-phosphate palmitaldehyde-lyase (phosphoethanolamine-forming) inhibitors
sphinganine-1-phosphate palmitaldehyde-lyase inhibitor
sphinganine-1-phosphate palmitaldehyde-lyase inhibitors
sphingosine-1-phosphate aldolase inhibitor
sphingosine-1-phosphate aldolase inhibitors
sphingosine-1-phosphate lyase inhibitors
An EC 4.1.* (C-C lyase) inhibitor that interferes with the action of any aldehyde-lyase (EC 4.1.2.*).
A Daphnia metabolite produced by the species Daphnia galeata.
An animal metabolite produced by arthropods such as crabs, lobsters, crayfish, shrimps and krill.
A Daphnia metabolite produced by the species Daphnia magna.
A crustacean metabolite produced by the genus of small planktonic arthropods, Daphnia
EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor
An EC 1.3.5.* (oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor) inhibitor that interferes with the action of succinate dehydrogenase (quinone), EC 1.3.5.1.
EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitors
succinate dehydrogenase (ubiquinone) inhibitor
succinate dehydrogenase (ubiquinone) inhibitors
succinate dehydrogenase complex inhibitor
succinate dehydrogenase complex inhibitors
succinate:quinone oxidoreductase inhibitor
succinate:quinone oxidoreductase inhibitors
succinate:ubiquinone oxidoreductase inhibitor
succinate:ubiquinone oxidoreductase inhibitors
A semiochemical used for inter-species chemical communication in a way that benefits an individual of another species that receives the chemical signal.
A Daphnia metabolite produced by the species Daphnia pulex.
A Daphnia metabolite produced by the species Daphnia tenebrosa.
EC 6.2.1.* (acid-thiol ligase) inhibitor
An EC 6.2.* (C-S bond-forming ligase) inhibitor that interferes with the action of an acid-thiol ligase inhibitor (EC 6.2.1.*).
EC 6.2.1.* (acid-thiol ligase) inhibitors
EC 6.2.1.* (acid-thiol ligases) inhibitor
EC 6.2.1.* (acid-thiol ligases) inhibitors
EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitor
An EC 6.2.1.* (acid-thiol ligase) inhibitor that interferes with the action of a long-chain-fatty-acid--CoA ligase (EC 6.2.1.3).
EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitors
fatty acid thiokinase (long chain) inhibitor
fatty acid thiokinase (long chain) inhibitors
fatty acyl-coenzyme A synthetase inhibitor
fatty acyl-coenzyme A synthetase inhibitors
long chain fatty acyl-CoA synthetase inhibitor
long chain fatty acyl-CoA synthetase inhibitors
long-chain acyl CoA synthetase inhibitor
long-chain acyl CoA synthetase inhibitors
long-chain acyl-CoA synthetase I inhibitor
long-chain acyl-CoA synthetase I inhibitors
long-chain acyl-CoA synthetase II inhibitor
long-chain acyl-CoA synthetase II inhibitors
long-chain acyl-coenzyme A synthetase inhibitor
long-chain acyl-coenzyme A synthetase inhibitors
long-chain fatty acid:CoA ligase (AMP-forming) inhibitor
long-chain fatty acid:CoA ligase (AMP-forming) inhibitors
long-chain fatty acyl coenzyme A synthetase inhibitor
long-chain fatty acyl coenzyme A synthetase inhibitors
palmitoyl coenzyme A synthetase inhibitor
palmitoyl coenzyme A synthetase inhibitors
An antagonist that binds to and deactivates orexin receptors.
protease-activated receptor-1 antagonist
An antagonist at the protease-activated receptor-1.
coagulation factor II (thrombin) receptor antagonist
coagulation factor II (thrombin) receptor antagonists
coagulation factor II receptor antagonist
coagulation factor II receptor antagonists
coagulation factor II thrombin receptor antagonist
coagulation factor II thrombin receptor antagonists
protease activated receptor 1 antagonist
protease activated receptor 1 antagonists
protease-activated receptor 1 antagonist
protease-activated receptor 1 antagonists
protease-activated receptor-1 antagonists
proteinase-activated receptor 1 antagonist
proteinase-activated receptor 1 antagonists
EC 1.14.13.72 (methylsterol monooxygenase) inhibitor
4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,NAD(P)H:oxygen oxidoreductase (hydroxylating) inhibitor
4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,NAD(P)H:oxygen oxidoreductase (hydroxylating) inhibitors
4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,hydrogen-donor:oxygen oxidoreductase (hydroxylating) inhibitor
4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,hydrogen-donor:oxygen oxidoreductase (hydroxylating) inhibitors
An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of methylsterol monooxygenase (EC 1.14.13.72).
EC 1.14.13.72 (ethylsterol monooxygenase) inhibitors
methylsterol monooxygenase (EC 1.14.13.72) inhibitor
methylsterol monooxygenase (EC 1.14.13.72) inhibitors
Any compound that inhibits the biosynthesis of any sterol.
EC 1.3.1.70 (Delta(14)-sterol reductase) inhibitor
4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol:NADP(+) Delta(14)-oxidoreductase inhibitor
4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol:NADP(+) Delta(14)-oxidoreductase inhibitors
An EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of Delta(14)-sterol reductase (EC 1.3.1.70).
Delta(14)-sterol reductase (EC 1.3.1.70) inhibitor
Delta(14)-sterol reductase (EC 1.3.1.70) inhibitors
EC 1.3.1.70 (Delta(14)-sterol reductase) inhibitors
Any metabolite produced by metabolism of a xenobiotic compound in marine macro- and microorganisms.
Any agent capable of inducing steatosis, a pathological condition characterised by accumulation or abnormal retention of fats within a cell.
Any hepatotoxic agent capable of inducing liver steatosis or fatty liver disease.
A sterol biosynthesis inhibitor that acts by inhibiting the C14 demethylation step within fungal steroid biosynthesis.
Any compound that inhibits the biosynthesis of any phospholipid.
EC 2.4.1.231 [alpha,alpha-trehalose phosphorylase (configuration-retaining)] inhibitor
An EC 2.4.1.* (hexosyltransferase) inhibitor that interferes with the action of alpha,alpha-trehalose phosphorylase (configuration-retaining) (EC 2.4.1.231).
EC 2.4.1.231 [alpha,alpha-trehalose phosphorylase (configuration-retaining)] inhibitors
alpha,alpha-trehalose phosphorylase (configuration-retaining) (EC 2.4.1.231) inhibitor
alpha,alpha-trehalose phosphorylase (configuration-retaining) (EC 2.4.1.231) inhibitors
alpha,alpha-trehalose phosphorylase (configuration-retaining) inhibitor
alpha,alpha-trehalose phosphorylase (configuration-retaining) inhibitors
alpha,alpha-trehalose:phosphate alpha-D-glucosyltransferase inhibitor
alpha,alpha-trehalose:phosphate alpha-D-glucosyltransferase inhibitors
EC 2.4.1.64 (alpha,alpha-trehalose phosphorylase) inhibitor
An EC 2.4.1.* (hexosyltransferase) inhibitor that interferes with the action of alpha,alpha-trehalose phosphorylase (EC 2.4.1.64).
EC 2.4.1.64 (alpha,alpha-trehalose phosphorylase) inhibitors
alpha,alpha-trehalose phosphorylase (EC 2.4.1.64) inhibitor
alpha,alpha-trehalose phosphorylase (EC 2.4.1.64) inhibitors
alpha,alpha-trehalose phosphorylase inhibitor
alpha,alpha-trehalose phosphorylase inhibitors
alpha,alpha-trehalose:phosphate beta-D-glucosyltransferase inhibitor
alpha,alpha-trehalose:phosphate beta-D-glucosyltransferase inhibitors
EC 3.2.1.28 (alpha,alpha-trehalase) inhibitor
An EC 2.4.1.* (hexosyltransferase) inhibitor that interferes with the action of alpha,alpha-trehalase (EC 2.4.1.28).
EC 3.2.1.28 (alpha,alpha-trehalase) inhibitors
alpha,alpha-trehalase (EC 3.2.1.28) inhibitor
alpha,alpha-trehalase (EC 3.2.1.28) inhibitors
Any inhibitor of nonstructural protein 5A.
HCV non-structural protein 5A inhibitors
EC 4.2.1.94 (scytalone dehydratase) inhibitor
An EC 4.2.1.* (hydro-lyases) inhibitor that interferes with the action of scytalone dehydratase (EC 4.2.1.94).
EC 4.2.1.94 (scytalone dehydratase) inhibitors
scytalone 7,8-hydro-lyase (1,3,8-trihydroxynaphthalene-forming) inhibitor
scytalone 7,8-hydro-lyase (1,3,8-trihydroxynaphthalene-forming) inhibitors
An EC 3.4.24.* (metalloendopeptidase) inhibitor that interferes with the action of gelatinase A (EC 3.4.24.24).
type IV collagenase/gelatinase inhibitor
type IV collagenase/gelatinase inhibitors
Any metabolite (endogenous or exogenous) found in human urine samples.
An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of nicotinamidase (EC 3.5.1.19).
An EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of peptidase K (EC 3.4.21.64).
Tritirachium album proteinase K inhibitor
Tritirachium album proteinase K inhibitors
Tritirachium album serine proteinase inhibitor
Tritirachium album serine proteinase inhibitors
Any eukaryotic metabolite produced during a metabolic reaction in algae including unicellular organisms like chlorella and diatoms to multicellular organisms like giant kelps and brown algae.
EC 2.3.1.5 (arylamine N-acetyltransferase) inhibitor
2-naphthylamine N-acetyltransferase inhibitor
2-naphthylamine N-acetyltransferase inhibitors
4-aminobiphenyl N-acetyltransferase inhibitor
4-aminobiphenyl N-acetyltransferase inhibitors
An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of arylamine N-acetyltransferase (EC 2.3.1.5).
EC 2.3.1.5 (arylamine N-acetyltransferase) inhibitors
acetyl CoA-arylamine N-acetyltransferase inhibitor
acetyl CoA-arylamine N-acetyltransferase inhibitors
acetyl-CoA:arylamine N-acetyltransferase inhibitor
acetyl-CoA:arylamine N-acetyltransferase inhibitors
arylamine N-acetyltransferase (EC 2.3.1.5) inhibitor
arylamine N-acetyltransferase (EC 2.3.1.5) inhibitors
arylamine N-acetyltransferase inhibitors
beta-naphthylamine N-acetyltransferase inhibitor
beta-naphthylamine N-acetyltransferase inhibitors
indoleamine N-acetyltransferase inhibitor
indoleamine N-acetyltransferase inhibitors
p-aminosalicylate N-acetyltransferase inhibitor
p-aminosalicylate N-acetyltransferase inhibitors
serotonin N-acetyltransferase inhibitors
EC 2.4.1.1 (glycogen phosphorylase) inhibitor
(1->4)-alpha-D-glucan:phosphate alpha-D-glucosyltransferase inhibitor
(1->4)-alpha-D-glucan:phosphate alpha-D-glucosyltransferase inhibitors
1,4-alpha-D-glucan:phosphate alpha-D-glucosyltransferase inhibitor
1,4-alpha-D-glucan:phosphate alpha-D-glucosyltransferase inhibitors
1,4-alpha-glucan phosphorylase inhibitor
1,4-alpha-glucan phosphorylase inhibitors
Any EC 2.4.1.* (hexosyltransferase) inhibitor that interferes with the action of glycogen phosphorylase (EC 2.4.1.1).
EC 2.4.1.1 (glycogen phosphorylase) inhibitors
glycogen phosphorylase (EC 2.4.1.1) inhibitor
glycogen phosphorylase (EC 2.4.1.1) inhibitors
EC 2.7.1.127 (inositol-trisphosphate 3-kinase) inhibitor
1D-myo-inositol-trisphosphate 3-kinase inhibitor
1D-myo-inositol-trisphosphate 3-kinase inhibitors
ATP:1D-myo-inositol-1,4,5-trisphosphate 3-phosphotransferase inhibitor
ATP:1D-myo-inositol-1,4,5-trisphosphate 3-phosphotransferase inhibitors
Any EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor that interferes with the action of inositol-trisphosphate 3-kinase (EC 2.7.1.127).
EC 2.7.1.127 (inositol-trisphosphate 3-kinase) inhibitors
inositol 1,4,5-trisphosphate 3-kinase inhibitor
inositol 1,4,5-trisphosphate 3-kinase inhibitors
inositol-trisphosphate 3-kinase (EC 2.7.1.127) inhibitor
inositol-trisphosphate 3-kinase (EC 2.7.1.127) inhibitors
inositol-trisphosphate 3-kinase inhibitor
inositol-trisphosphate 3-kinase inhibitors
EC 2.7.1.151 (inositol-polyphosphate multikinase) inhibitor
ATP:1D-myo-inositol-1,4,5-trisphosphate 6-phosphotransferase inhibitor
ATP:1D-myo-inositol-1,4,5-trisphosphate 6-phosphotransferase inhibitors
Any EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor that interferes with the action of inositol-polyphosphate multikinase (EC 2.7.1.151).
EC 2.7.1.151 (inositol-polyphosphate multikinase) inhibitors
IP3/IP4 dual-specificity 6-/3-kinase inhibitor
IP3/IP4 dual-specificity 6-/3-kinase inhibitors
inositol polyphosphate 6-/3-/5-kinase inhibitor
inositol polyphosphate 6-/3-/5-kinase inhibitors
inositol-polyphosphate multikinase (EC 2.7.1.151) inhibitor
inositol-polyphosphate multikinase (EC 2.7.1.151) inhibitors
inositol-polyphosphate multikinase inhibitor
inositol-polyphosphate multikinase inhibitors
EC 2.7.4.* (phosphotransferases with a phosphate group as acceptor) inhibitor
Any EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any phosphotransferase with a phosphate group as acceptor (EC 2.7.4.*).
EC 2.7.4.* (phosphotransferases with a phosphate group as acceptor) inhibitors
phosphotransferases with a phosphate group as acceptor (EC 2.7.4.*) inhibitor
phosphotransferases with a phosphate group as acceptor (EC 2.7.4.*) inhibitors
EC 2.7.4.6 (nucleoside-diphosphate kinase) inhibitor
ATP:nucleoside-diphosphate phosphotransferase inhibitor
ATP:nucleoside-diphosphate phosphotransferase inhibitors
Any EC 2.7.4.* (phosphotransferases with a phosphate group as acceptor) inhibitor that interferes with the action of nucleoside-diphosphate kinase (EC 2.7.4.6).
EC 2.7.4.6 (nucleoside-diphosphate kinase) inhibitors
nucleoside 5'-diphosphate kinase inhibitor
nucleoside 5'-diphosphate kinase inhibitors
nucleoside diphosphate (UDP) kinase inhibitor
nucleoside diphosphate (UDP) kinase inhibitors
nucleoside-diphosphate kinase (EC 2.7.4.6) inhibitor
nucleoside-diphosphate kinase (EC 2.7.4.6) inhibitors
nucleoside-diphosphate kinase inhibitors
EC 2.6.1.16 (glutamine--fructose-6-phosphate transaminase (isomerizing)) inhibitor
An EC 2.6.1.* (transaminase) inhibitor that interferes with the action of glutamine--fructose-6-phosphate transaminase (isomerizing) (EC 2.6.1.19).
D-fructose-6-phosphate amidotransferase inhibitor
D-fructose-6-phosphate amidotransferase inhibitors
EC 2.6.1.16 (glutamine--fructose-6-phosphate transaminase (isomerizing)) inhibitors
L-glutamine-D-fructose-6-phosphate amidotransferase inhibitor
L-glutamine-D-fructose-6-phosphate amidotransferase inhibitors
L-glutamine:D-fructose-6-phosphate isomerase (deaminating) inhibitor
L-glutamine:D-fructose-6-phosphate isomerase (deaminating) inhibitors
glucosamine 6-phosphate synthase inhibitor
glucosamine 6-phosphate synthase inhibitors
glucosamine-6-phosphate isomerase (glutamine-forming) inhibitor
glucosamine-6-phosphate isomerase (glutamine-forming) inhibitors
glucosamine-6-phosphate synthase inhibitor
glucosamine-6-phosphate synthase inhibitors
glucosaminephosphate isomerase inhibitor
glucosaminephosphate isomerase inhibitors
hexosephosphate aminotransferase inhibitor
hexosephosphate aminotransferase inhibitors
An agonist that selectively binds to and activates the thrombopoietin receptor [myeloproliferative leukemia protein or CD110 (Cluster of Differentiation 110)].
Any cosmetic used to lighten the colour of skin by reducing the concentration of melanin.
EC 1.10.3.* (oxidoreductase acting on diphenols and related substances as donors with oxygen as acceptor) inhibitor
An EC 1.10.* (oxidoreductase acting on diphenols and related substances as donors) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.10.3.*).
EC 1.10.3.* (oxidoreductase acting on diphenols and related substances as donors with oxygen as acceptor) inhibitors
EC 1.10.3.1 (catechol oxidase) inhibitor
1,2-benzenediol:oxygen oxidoreductase inhibitor
1,2-benzenediol:oxygen oxidoreductase inhibitors
Any EC 1.10.3.* (oxidoreductase acting on diphenols and related substances as donors with oxygen as acceptor) inhibitor that interferes with the action of catechol oxidase (EC 1.10.3.1).
EC 1.10.3.1 (catechol oxidase) inhibitors
catechol oxidase (EC 1.10.3.1) inhibitor
catechol oxidase (EC 1.10.3.1) inhibitors
o-diphenol:oxygen oxidoreductase inhibitor
o-diphenol:oxygen oxidoreductase inhibitors
Any EC 1.10.3.* (oxidoreductase acting on diphenols and related substances as donors with oxygen as acceptor) inhibitor that interferes with the action of laccase (EC 1.10.3.2).
benzenediol:oxygen oxidoreductase inhibitor
benzenediol:oxygen oxidoreductase inhibitors
EC 1.13.11.24 (quercetin 2,3-dioxygenase) inhibitor
Any EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitor that interferes with the action of quercetin 2,3-dioxygenase (EC 1.13.1.24).
EC 1.13.11.24 (quercetin 2,3-dioxygenase) inhibitors
quercetin 2,3-dioxygenase (EC 1.13.11.24) inhibitor
quercetin 2,3-dioxygenase (EC 1.13.11.24) inhibitors
quercetin:oxygen 2,3-oxidoreductase (decyclising) inhibitor
quercetin:oxygen 2,3-oxidoreductase (decyclising) inhibitors
quercetin:oxygen 2,3-oxidoreductase (decyclizing) inhibitor
quercetin:oxygen 2,3-oxidoreductase (decyclizing) inhibitors
quercetin:oxygen 2,3-oxidoreductase (ring-opening) inhibitor
quercetin:oxygen 2,3-oxidoreductase (ring-opening) inhibitors
EC 1.4.3.3 (D-amino-acid oxidase) inhibitor
Any EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor that interferes with the action of D-amino-acid oxidase (EC 1.4.3.3).
D-amino-acid oxidase (EC 1.4.3.3) inhibitor
D-amino-acid oxidase (EC 1.4.3.3) inhibitors
D-amino-acid:oxygen oxidoreductase (deaminating) inhibitor
D-amino-acid:oxygen oxidoreductase (deaminating) inhibitors
EC 1.4.3.3 (D-amino-acid oxidase) inhibitors
L-amino acid:O2 oxidoreductase inhibitor
L-amino acid:O2 oxidoreductase inhibitors
EC 2.7.11.31 {[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase} activator
3-hydroxy-3-methylglutaryl coenzyme A reductase kinase activator
3-hydroxy-3-methylglutaryl coenzyme A reductase kinase activators
3-hydroxy-3-methylglutaryl-CoA reductase kinase activator
3-hydroxy-3-methylglutaryl-CoA reductase kinase activators
ATP:[hydroxymethylglutaryl-CoA reductase (NADPH)] phosphotransferase activator
ATP:[hydroxymethylglutaryl-CoA reductase (NADPH)] phosphotransferase activators
Any compound that binds to and activates the enzyme [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase (EC 2.7.11.31).
EC 2.7.11.31 ([hydroxymethylglutaryl-CoA reductase (NADPH)] kinase) activator
EC 2.7.11.31 ([hydroxymethylglutaryl-CoA reductase (NADPH)] kinase) activators
EC 2.7.11.31 {[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase} activators
[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activator
[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activators
[hydroxymethylglutaryl-CoA reductase (NADPH2)] kinase activator
[hydroxymethylglutaryl-CoA reductase (NADPH2)] kinase activators
beta-hydroxy-beta-methylglutaryl-CoA reductase kinase activator
beta-hydroxy-beta-methylglutaryl-CoA reductase kinase activators
hydroxymethylglutaryl coenzyme A reductase kinase (phosphorylating) activator
hydroxymethylglutaryl coenzyme A reductase kinase (phosphorylating) activators
hydroxymethylglutaryl coenzyme A reductase kinase activator
hydroxymethylglutaryl coenzyme A reductase kinase activators
hydroxymethylglutaryl-CoA reductase kinase activator
hydroxymethylglutaryl-CoA reductase kinase activators
EC 2.7.11.11 (cAMP-dependent protein kinase) inhibitor
ATP:protein phosphotransferase (cAMP-dependent) inhibitor
ATP:protein phosphotransferase (cAMP-dependent) inhibitors
An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of cAMP-dependent protein kinase (EC 2.7.11.11).
EC 2.7.11.11 (cAMP-dependent protein kinase) inhibitors
cAMP-dependent protein kinase (EC 2.7.11.11) inhibitor
cAMP-dependent protein kinase (EC 2.7.11.11) inhibitors
EC 2.7.11.12 (cGMP-dependent protein kinase) inhibitor
3':5'-cyclic GMP-dependent protein kinase inhibitor
3':5'-cyclic GMP-dependent protein kinase inhibitors
ATP:protein phosphotransferase (cGMP-dependent) inhibitor
ATP:protein phosphotransferase (cGMP-dependent) inhibitors
An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of cGMP-dependent protein kinase (EC 2.7.11.12).
EC 2.7.11.12 (cGMP-dependent protein kinase) inhibitors
cGMP-dependent protein kinase (EC 2.7.11.12) inhibitor
cGMP-dependent protein kinase (EC 2.7.11.12) inhibitors
cGMP-dependent protein kinase Ibeta inhibitor
cGMP-dependent protein kinase Ibeta inhibitors
guanosine 3':5'-cyclic monophosphate-dependent protein kinase inhibitor
guanosine 3':5'-cyclic monophosphate-dependent protein kinase inhibitors
nonnucleoside hepatitis C virus polymerase inhibitor
Any inhibitor of nonnucleoside hepatitis C virus polymerase.
nonnucleoside hepatitis C virus polymerase inhibitors
hepatitis C virus nonstructural protein 5A inhibitor
Any inhibitor of hepatitis C virus nonstructural protein 5A.
hepatitis C virus nonstructural protein 5A inhibitors
Any metabolite (endogenous or exogenous) found in human blood serum samples.
A compound that inhibits the re-uptake of the neurotransmitter GABA from the synapse into the pre-synaptic neuron, so increasing the extracellular concentrations of the neurotransmitter and hence increasing neurotransmission.
gamma-aminobutyric acid re-uptake inhibitor
gamma-aminobutyric acid re-uptake inhibitors
gamma-aminobutyric acid reuptake inhibitor
gamma-aminobutyric acid reuptake inhibitors
Any glycine transporter inhibitor that interferes with the action of glycine 2 transporters.
Any substance that inhibits the action of glycine transporters.
An antagonist that binds to and deactivates thromboxane A2 receptors.
EC 2.5.1.31 {ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific]} inhibitor
(2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate cistransferase (adding 8 isopentenyl units) inhibitor
(2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate cistransferase (adding 8 isopentenyl units) inhibitors
An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific].
EC 2.5.1.31 {ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific]} inhibitors
bactoprenyl-diphosphate synthase inhibitor
bactoprenyl-diphosphate synthase inhibitors
ditrans,polycis-undecaprenyl-diphosphate synthase inhibitor
ditrans,polycis-undecaprenyl-diphosphate synthase inhibitors
ditrans,polycis-undecaprenylcistransferase inhibitor
ditrans,polycis-undecaprenylcistransferase inhibitors
undecaprenyl diphosphate synthetase inhibitor
undecaprenyl diphosphate synthetase inhibitors
undecaprenyl pyrophosphate synthase inhibitor
undecaprenyl pyrophosphate synthase inhibitors
undecaprenyl pyrophosphate synthetase inhibitor
undecaprenyl pyrophosphate synthetase inhibitors
undecaprenyl-diphosphate synthase inhibitor
undecaprenyl-diphosphate synthase inhibitors
EC 1.4.1.* (oxidoreductase acting on donor CH-NH2 group; NAD(+) or NADP(+) as acceptor) inhibitor
Any EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor that interferes with the action any such enzyme that has NAD(+) or NADP(+) as acceptor.
EC 1.4.1.* (oxidoreductase acting on donor CH-NH2 group with NAD(+) or NADP(+) as acceptor) inhibitor
EC 1.4.1.* (oxidoreductase acting on donor CH-NH2 group with NAD(+) or NADP(+) as acceptor) inhibitors
EC 1.4.1.* (oxidoreductase acting on donor CH-NH2 group; NAD(+) or NADP(+) as acceptor) inhibitors
EC 1.4.1.3 {glutamate dehydrogenase [NAD(P)(+)]} inhibitor
An EC 1.4.1.* (oxidoreductase acting on donor CH-NH2 group; NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of glutamate dehydrogenase [NAD(P)(+)] (EC 1.4.1.3).
EC 1.4.1.3 {glutamate dehydrogenase [NAD(P)(+)]} inhibitors
L-glutamate:NAD(P)(+) oxidoreductase (deaminating) inhibitor
L-glutamate:NAD(P)(+) oxidoreductase (deaminating) inhibitors
glutamate dehydrogenase [NAD(P)(+)] (EC 1.4.1.3) inhibitor
glutamate dehydrogenase [NAD(P)(+)] (EC 1.4.1.3) inhibitors
glutamate dehydrogenase [NAD(P)(+)] inhibitor
glutamate dehydrogenase [NAD(P)(+)] inhibitors
Any compound that acts as an agonist towards the liver X receptors.
Any mammalian metabolite produced during a metabolic reaction in rat (Rattus norvegicus).
Any antifungal agent used to prevent or treat fungal infections in humans or animals.
Any substance used in acriculture, horticulture, forestry, etc. for its fungicidal properties.
EC 5.3.3.* (intramolecular oxidase transposing C=C bonds) inhibitor
An EC 5.3.* (intramolecular oxidoreductase) inhibitor that inhibits the action of any such enzyme that transposes C=C bonds (EC 5.3.3.*).
EC 5.3.3.* (intramolecular oxidase transposing C=C bonds) inhibitors
intramolecular oxidase transposing C=C bonds inhibitor (EC 5.3.3.*) inhibitor
intramolecular oxidase transposing C=C bonds inhibitor (EC 5.3.3.*) inhibitors
EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor
An EC 5.3.3.* (intramolecular oxidase transposing C=C bonds) inhibitor that interferes with the action of a cholestenol Delta-isomerase (EC 5.3.3.5).
Delta(7)-cholestenol Delta(7)-Delta(8)-isomerase inhibitor
Delta(7)-cholestenol Delta(7)-Delta(8)-isomerase inhibitors
EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitors
cholestenol Delta-isomerase (EC 5.3.3.5) inhibitor
cholestenol Delta-isomerase (EC 5.3.3.5) inhibitors
EC 1.14.13.78 (ent-kaurene oxidase) inhibitor
An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of ent-kaurene oxidase (E.C. 1.14.13.78).
EC 1.14.13.78 (ent-kaurene oxidase) inhibitors
ent-kaurene oxidase (EC 1.14.13.78) inhibitor
ent-kaurene oxidase (EC 1.14.13.78) inhibitors
EC 1.14.13.97 (taurochenodeoxycholate 6alpha-hydroxylase) inhibitor
An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of EC 1.14.13.97 (taurochenodeoxycholate 6alpha-hydroxylase).
EC 1.14.13.97 (taurochenodeoxycholate 6alpha-hydroxylase) inhibitors
taurochenodeoxycholate 6alpha-hydroxylase inhibitor
taurochenodeoxycholate 6alpha-hydroxylase inhibitors
taurochenodeoxycholate 6alpha-monooxygenase inhibitor
taurochenodeoxycholate 6alpha-monooxygenase inhibitors
taurochenodeoxycholate,NADPH:oxygen oxidoreductase (6alpha-hydroxylating) inhibitor
taurochenodeoxycholate,NADPH:oxygen oxidoreductase (6alpha-hydroxylating) inhibitors
EC 3.4.21.92 (endopeptidase Clp) inhibitor
Any EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of endopeptidase Clp (EC 3.4.21.92).
EC 3.4.21.92 (endopeptidase Clp) inhibitors
An inhibitor of signal transducer and activator of transcription 3 (STAT3)
signal transducer and activator of transcription 3 inhibitor
signal transducer and activator of transcription 3 inhibitors
Mothers against decapentaplegic homolog 3 inhibitors
Mothers against decapentaplegic homologue 3 inhibitor
Mothers against decapentaplegic homologue 3 inhibitors
mothers against decapentaplegic homolog 3 inhibitor
signal transducer and activator of transcription 5 protein inhibitor
Any inhibitor of signal transducer and activator of transcription 5 protein
signal transducer and activator of transcription 5 protein inhibitors
Any toxin produced by cyanobacteria (blue-green algae).
Any drug which causes the onset of an allergic reaction.
Any ionophore capable of transportation of potassium ions across membranes.
Any compound that inhibits the process of autophagy (the self-digestion of one or more components of a cell through the action of enzymes originating within the same cell).
EC 2.7.12.* [dual-specificity kinases (those acting on Ser/Thr and Tyr residues)] inhibitor
An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of duals specificity kinases acting on Ser/Thr and Tyr residues.
EC 2.7.12.* [dual-specificity kinases (those acting on Ser/Thr and Tyr residues)] inhibitors
inhibitor of dual-specificity kinases (those acting on Ser/Thr and Tyr residues) (EC 2.7.12.*)
inhibitors of dual-specificity kinases (those acting on Ser/Thr and Tyr residues) (EC 2.7.12.*)
EC 2.7.12.2 (mitogen-activated protein kinase kinase) inhibitor
ATP:protein phosphotransferase (MAPKKK-activated) inhibitor
ATP:protein phosphotransferase (MAPKKK-activated) inhibitors
An EC 2.7.12.* [dual-specificity kinases (those acting on Ser/Thr and Tyr residues)] inhibitor that inhibits the action of mitogen-activated protein kinase kinase (EC 2.7.12.2).
EC 2.7.12.2 (mitogen-activated protein kinase kinase) inhibitors
mitogen-activated protein kinase kinase (EC 2.7.12.2) inhibitor
mitogen-activated protein kinase kinase (EC 2.7.12.2) inhibitors
mitogen-activated protein kinase kinase inhibitor
mitogen-activated protein kinase kinase inhibitors
An antagonist at G-protein-coupled receptor.
Any retinoic acid receptor (RAR) agonist with specificity for RARgamma.
nuclear receptor subfamily 1, group B, member 3 agonist
nuclear receptor subfamily 1, group B, member 3 agonists
An activator of alpha-secretase, one of the three endopeptidases that are specific for amyloid protein precursor and which have been identified based upon the region of the amyloid protein precursor which they cleave.
EC 1.1.1.170 [3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)] inhibitor
3beta-hydroxy-4alpha-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating) inhibitor
3beta-hydroxy-4alpha-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating) inhibitors
3beta-hydroxy-4beta-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating) inhibitor
3beta-hydroxy-4beta-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating) inhibitors
3beta-hydroxy-4beta-methylcholestenoate dehydrogenase inhibitor
3beta-hydroxy-4beta-methylcholestenoate dehydrogenase inhibitors
3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating) (EC 1.1.1.170) inhibitor
3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating) (EC 1.1.1.170) inhibitors
3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating) inhibitor
3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating) inhibitors
3beta-hydroxysteroid-4alpha-carboxylate:NAD(P)(+) 3-oxidoreductase (decarboxylating) inhibitor
3beta-hydroxysteroid-4alpha-carboxylate:NAD(P)(+) 3-oxidoreductase (decarboxylating) inhibitors
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating) (EC 1.1.1.170).
EC 1.1.1.170 [3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)] inhibitors
sterol 4alpha-carboxylic decarboxylase inhibitor
sterol 4alpha-carboxylic decarboxylase inhibitors
sterol-4alpha-carboxylate 3-dehydrogenase (decarboxylating) inhibitor
sterol-4alpha-carboxylate 3-dehydrogenase (decarboxylating) inhibitors
An EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor that inhibits the action of c-Jun N-terminal kinase.
EC 2.1.1.37 [DNA (cytosine-5-)-methyltransferase] inhibitor
An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of DNA (cytosine-5-)-methyltransferase (EC 2.1.1.37).
DNA-cytosine methyltransferase inhibitor
DNA-cytosine methyltransferase inhibitors
EC 2.1.1.37 [DNA (cytosine-5-)-methyltransferase] inhibitors
S-adenosyl-L-methionine:DNA (cytosine-5-)-methyltransferase inhibitor
S-adenosyl-L-methionine:DNA (cytosine-5-)-methyltransferase inhibitors
cytosine DNA methyltransferase inhibitor
cytosine DNA methyltransferase inhibitors
cytosine-specific DNA methyltransferase inhibitor
cytosine-specific DNA methyltransferase inhibitors
deoxyribonucleate methyltransferase inhibitor
deoxyribonucleate methyltransferase inhibitors
deoxyribonucleic (cytosine-5-)-methyltransferase inhibitor
deoxyribonucleic (cytosine-5-)-methyltransferase inhibitors
deoxyribonucleic acid (cytosine-5-)-methyltransferase inhibitor
deoxyribonucleic acid (cytosine-5-)-methyltransferase inhibitors
deoxyribonucleic acid methylase inhibitor
deoxyribonucleic acid methylase inhibitors
deoxyribonucleic acid methyltransferase inhibitor
deoxyribonucleic acid methyltransferase inhibitors
deoxyribonucleic acid modification methylase inhibitor
deoxyribonucleic acid modification methylase inhibitors
methylphosphotriester-DNA methyltransferase inhibitor
methylphosphotriester-DNA methyltransferase inhibitors
site-specific DNA-methyltransferase (cytosine-specific) inhibitor
site-specific DNA-methyltransferase (cytosine-specific) inhibitors
An EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor that interferes with the action of c-Met tyrosine kinase.
MET proto-oncogene, receptor tyrosine kinase inhibitor
MET proto-oncogene, receptor tyrosine kinase inhibitors
EC 4.1.1.23 (orotidine-5'-phosphate decarboxylase) inhibitor
Any EC 4.1.1.* (carboxy-lyase) inhibitor that interferes with the action of orotidine-5'-phosphate decarboxylase (EC 4.1.1.23).
EC 4.1.1.23 (orotidine-5'-phosphate decarboxylase) inhibitors
orotate monophosphate decarboxylase inhibitor
orotate monophosphate decarboxylase inhibitors
orotidine 5'-phosphate decarboxylase inhibitor
orotidine 5'-phosphate decarboxylase inhibitors
orotidine monophosphate decarboxylase inhibitor
orotidine monophosphate decarboxylase inhibitors
orotidine phosphate decarboxylase inhibitor
orotidine phosphate decarboxylase inhibitors
orotidine-5'-monophosphate decarboxylase inhibitor
orotidine-5'-monophosphate decarboxylase inhibitors
orotidine-5'-phosphate carboxy-lyase (UMP-forming) inhibitor
orotidine-5'-phosphate carboxy-lyase (UMP-forming) inhibitors
orotidine-5'-phosphate carboxy-lyase inhibitor
orotidine-5'-phosphate carboxy-lyase inhibitors
orotidine-5'-phosphate decarboxylase (EC 4.1.1.23) inhibitor
orotidine-5'-phosphate decarboxylase (EC 4.1.1.23) inhibitors
orotidylic acid decarboxylase inhibitors
uridine 5'-monophosphate synthase inhibitor
uridine 5'-monophosphate synthase inhibitors
EC 6.4.1.1 (pyruvate carboxylase) inhibitor
An EC 6.4.1.* (carboxylase) inhibitor that interferes with the action of pyruvate carboxylase (EC 6.4.1.1).
EC 6.4.1.1 (pyruvate carboxylase) inhibitors
pyruvate carboxylase (EC 6.4.1.1) inhibitor
pyruvate carboxylase (EC 6.4.1.1) inhibitors
pyruvate:carbon-dioxide ligase (ADP-forming) inhibitor
pyruvate:carbon-dioxide ligase (ADP-forming) inhibitors
EC 4.6.1.1 (adenylate cyclase) inhibitor
ATP diphosphate-lyase (cyclising) inhibitor
ATP diphosphate-lyase (cyclising) inhibitors
ATP diphosphate-lyase (cyclising; 3',5'-cyclic-AMP-forming) inhibitor
ATP diphosphate-lyase (cyclising; 3',5'-cyclic-AMP-forming) inhibitors
ATP diphosphate-lyase (cyclizing) inhibitor
ATP diphosphate-lyase (cyclizing) inhibitors
ATP diphosphate-lyase (cyclizing; 3',5'-cyclic-AMP-forming) inhibitor
ATP diphosphate-lyase (cyclizing; 3',5'-cyclic-AMP-forming) inhibitors
An EC 4.6.* (P-O lyase) inhibitor that interferes with the action of enzyme adenylate cyclase (EC 4.6.1.1).
EC 4.6.1.1 (adenylate cyclase) inhibitors
adenylate cyclase (EC 4.6.1.1) inhibitor
adenylate cyclase (EC 4.6.1.1) inhibitors
Any compound that binds to and activates the enzyme histone acetyltransferase (EC 2.3.1.48).
An EC 3.5.1.98 (histone deacetylase) inhibitor that interferes with the action of Sir1.
A substance that causes another substance to be secreted.
A secretagogue that causes the secretion of insulin.
EC 5.3.1.* (intramolecular oxidoreductase interconverting aldoses and ketoses) inhibitor
EC 5.3.1.1 (triose-phosphate isomerase) inhibitor
Any EC 5.3.1.* (intramolecular oxidoreductase interconverting aldoses and ketoses) inhibitor that interferes with the action of a triose-phosphate isomerase (EC 5.3.1.1).
D-glyceraldehyde-3-phosphate ketol-isomerase inhibitor
D-glyceraldehyde-3-phosphate ketol-isomerase inhibitors
EC 5.3.1.1 (triose-phosphate isomerase) inhibitors
triose-phosphate isomerase (EC 5.3.1.1) inhibitor
triose-phosphate isomerase (EC 5.3.1.1) inhibitors
A nuclear receptor modulator that affects the retinoic acid receptor
Any receptor modulator acting on nuclear receptors
A drug that acts as an antagonist, agonist, reverse agonist, or in some other fashion when interacting with cellular receptors.
A retinoic acid receptor antagonist that antagonises retinoic acid receptor alpha.
retinoic acid receptor alpha antagonists
An antagonist that acts at the retinoic acid receptor.
Any retinoic acid receptor (RAR) agonist with specificity for RARbeta.
A retinoic acid receptor antagonist that antagonises retinoic acid receptor gamma.
retinoic acid receptor gamma antagonists
A role borne by a molecule that acts to counteract or neutralize the deleterious effects of cyanide.
A role borne by a molecule that acts to counteract or neutralise the deleterious effects of organophosphates or acetylcholinesterase inhibitors (nerve agents).
antidote to acetylcholinesterase inhibitor poisoning
A role borne by a molecule that acts to counteract or neutralise the deleterious effects of opioids.
A role borne by a molecule that acts to counteract or neutralise the deleterious effects of benzodiazepines.
eukaryotic translation elongation factor 1alpha 1 inhibitor
Any compound that inihibits the human protein, eukaryotic translation elongation factor 1alpha 1.
eukaryotic translation elongation factor 1alpha 1 inhibitors
A serine/threonine kinase inhibitor that specifically inhibits RAC-alpha serine/threonine-protein kinase (ATK1).
RAC-alpha serine/threonine-protein kinase inhibitor
RAC-alpha serine/threonine-protein kinase inhibitors
An agonist that binds to and activates prostacyclin receptors
An inverse agonist that binds to the same receptor as a liver X receptor agonist, but which induces a pharmacological response opposite to that agonist.
A substance that binds to the same receptor binding-site as an agonist for that receptor, but which exerts the opposite pharmacological effect.
EC 2.4.2.4 (thymidine phosphorylase) inhibitor
An EC 2.4.2.* (pentosyltransferase) inhibitor that interferes with the action of thymidine phosphorylase (EC 2.4.2.4).
EC 2.4.2.4 (thymidine phosphorylase) inhibitors
pyrimidine deoxynucleoside phosphorylase inhibitor
pyrimidine deoxynucleoside phosphorylase inhibitors
thymidine-orthophosphate deoxyribosyltransferase inhibitor
thymidine-orthophosphate deoxyribosyltransferase inhibitors
thymidine:phosphate deoxy-D-ribosyltransferase inhibitor
thymidine:phosphate deoxy-D-ribosyltransferase inhibitors
thymidine:phosphate deoxy-alpha-D-ribosyltransferase inhibitor
thymidine:phosphate deoxy-alpha-D-ribosyltransferase inhibitors
EC 1.8.5.* (oxidoreductase acting on sulfur group donors, quinone or similar as acceptor) inhibitor
Any EC 1.8.* (oxidoreductase acting on sulfur group of donors) inhibitor that interferes with the action of any such enzyme using a quinone or similar compound as an acceptor.
EC 1.8.5.* (oxidoreductase acting on sulfur group donors, quinone or similar as acceptor) inhibitors
oxidoreductase acting on sulfur group donors, quinone or similar as acceptor (EC 1.8.5.*) inhibitor
oxidoreductase acting on sulfur group donors, quinone or similar as acceptor (EC 1.8.5.*) inhibitors
EC 1.8.5.4 (sulfide:quinone reductase) inhibitor
An EC 1.8.5.* (oxidoreductase acting on sulfur group donors, quinone or similar as acceptor) inhibitor that interferes with the action of sulfide:quinone reductase (EC 1.8.5.4).
EC 1.8.5.4 (sulfide:quinone reductase) inhibitors
sulfide:quinone oxidoreductase inhibitor
sulfide:quinone oxidoreductase inhibitors
sulfide:quinone reductase (EC 1.8.5.4) inhibitor
sulfide:quinone reductase (EC 1.8.5.4) inhibitors
An inhibitor that interferes with the dimerisation of extracellular signal-regulated kinase (ERK).
extracellular signal-regulated kinase dimerisation inhibitor
extracellular signal-regulated kinase dimerisation inhibitors
A compound that enhances the activity of a steroid receptor coactivator.
steroid receptor coactivator small molecule stimulator
steroid receptor coactivator small molecule stimulators
steroid receptor coactivator stimulators
A chemical compound that, when added to a liquid or gas, decreases the corrosion rate of a material, typically a metal or an alloy.
A GABA receptor agonist specific for GABAA receptors, ligand-gated ion channels (also known as ionotropic receptors).
Any inhibitor of erythropoietin, a glycoprotein hormone that controls erythropoiesis (red blood cell production).
An antagonist at purinergic P2 receptors
An antagonist at purinergic P2X receptors
Any compound that inhibits collagen cross-linking.
EC 2.7.11.26 (tau-protein kinase) inhibitor
ATP:[tau-protein] O-phosphotransferase inhibitor
ATP:[tau-protein] O-phosphotransferase inhibitors
ATP:tau-protein O-phosphotransferase inhibitor
ATP:tau-protein O-phosphotransferase inhibitors
An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of tau-protein kinase inhibitor (EC 2.7.11.26).
EC 2.7.11.26 (tau-protein kinase) inhibitors
glycogen synthase kinase-3beta inhibitor
glycogen synthase kinase-3beta inhibitors
An agonist that selectively binds to and activates elastin-laminin receptors.
EC 1.1.5.3 (glycerol-3-phosphate dehydrogenase) inhibitor
An EC 1.1.5.* (oxidoreductase acting on donor CH-OH group, quinone or similar compound as acceptor) inhibitor that interferes with the action of glycerol-3-phosphate dehydrogenase (EC 1.1.5.3).
EC 1.1.5.3 (glycerol-3-phosphate dehydrogenase) inhibitors
glycerol-3-phosphate dehydrogenase inhibitor
glycerol-3-phosphate dehydrogenase inhibitors
EC 1.1.5.* (oxidoreductase acting on donor CH-OH group, quinone or similar compound as acceptor) inhibitor
An EC 1.1.* (oxidoreductase acting on donor CH-OH group) inhibitor that interferes with the action of any such enzyme using a quinone or similar compound as acceptor (EC 1.1.5.*).
EC 1.1.5.* (oxidoreductase acting on donor CH-OH group, quinone or simliar compound as acceptor) inhibitors
oxidoreductase acting on donor CH-OH group, quinone or simliar compound as acceptor (EC 1.1.5.*) inhibitor
oxidoreductase acting on donor CH-OH group, quinone or simliar compound as acceptor (EC 1.1.5.*) inhibitors
Any activator of vascular endothelial growth factor (VEGF).
vascular endothelial growth factor activator
vascular endothelial growth factor activators
vascular endothelial growth factor inducer
vascular endothelial growth factor inducers
lysophosphatidic acid receptor antagonist
An antagonist that binds to and deactivates lysophosphatidic acid receptors.
lysophosphatidic acid receptor antagonists
An antagonist that binds to and deactivates TGFbeta receptors.
transforming growth factor receptor antagonist
transforming growth factor receptor antagonists
macrophage migration inhibitory factor inhibitor
Any inhibitor of macrophage migration inhibitory factor (MIF).
macrophage migration inhibitory factor inhibitors
(2,3-Dichloro-4-(2-thenoyl)phenoxy)acetic acid
(2,3-Dichloro-4-(2-thiophenecarbonyl)phenoxy)acetic acid
4-(2-Thienylketo)-2,3-dichlorophenoxyacetic acid
An aromatic ketone that is 2,3-dichlorophenoxyacetic acid in which the hydrogen at position 4 on the benzene ring is replaced by a thiophenecarbonyl group. A loop diuretic used to treat hypertension, it was withdrawn from the market in 1982 due to links with hepatitis.
[2,3-dichloro-4-(2-thienylcarbonyl)phenoxy]acetic acid