definition
type: AnnotationProperty
definition source: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>
term editor: PERSON:Daniel Schober
definition: The official definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions.
editor preferred term: definition
has curation status: IAO_0000122

editor note
type: AnnotationProperty
definition: An administrative note intended for its editor. It may not be included in the publication version of the ontology, so it should contain nothing necessary for end users to understand the ontology.
definition source: GROUP:OBI:<http://purl.obfoundry.org/obo/obi>
term editor: PERSON:Daniel Schober
editor preferred term: editor note
has curation status: IAO_0000122

imported from
type: AnnotationProperty

has curation status
type: AnnotationProperty
definition source: OBI_0000281
term editor: PERSON:Alan Ruttenberg
term editor: PERSON:Bill Bug
term editor: PERSON:Melanie Courtot
editor preferred term: has curation status

definition source
type: AnnotationProperty
definition source: Discussion on obo-discuss mailing-list, see http://bit.ly/hgm99w
definition source: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>
term editor: PERSON:Daniel Schober
editor preferred term: definition source
definition: formal citation, e.g. identifier in external database to indicate / attribute source(s) for the definition. Free text indicate / attribute source(s) for the definition. EXAMPLE: Author Name, URI, MeSH Term C04, PUBMED ID, Wiki uri on 31.01.2007
has curation status: IAO_0000122

term editor
type: AnnotationProperty
editor note: 20110707, MC: label update to term editor and definition modified accordingly. See http://code.google.com/p/information-artifact-ontology/issues/detail?id=115.
definition source: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>
definition: Name of editor entering the term in the file. The term editor is a point of contact for information regarding the term. The term editor may be, but is not always, the author of the definition, which may have been worked upon by several people
term editor: PERSON:Daniel Schober
editor preferred term: term editor
has curation status: IAO_0000122

alternative term
type: AnnotationProperty
definition: An alternative name for a class or property which means the same thing as the preferred name (semantically equivalent)
definition source: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>
term editor: PERSON:Daniel Schober
editor preferred term: alternative term
has curation status: IAO_0000125

editor preferred term
type: AnnotationProperty
definition source: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>
term editor: PERSON:Daniel Schober
definition: The concise, meaningful, and human-friendly name for a class or property preferred by the ontology developers. (US-English)
editor preferred term: editor preferred term
has curation status: IAO_0000122

cell line cell
type: Class
subclass of: BAO_0003114
comment: A 'cell line cell' is a is part of a cell line established through the passaging/selection of a primary cultured cells or the experimental modification of an existing cell line. New types of cell line cells are established after sufficient passaging of a primary culture to establish a stable and homogenous population that qualifies as a line (typically 1-20 passages), or following some spontaneous or experimental modification that confers novel characteristics to an existing line. A cell line cell typically has mutations of five or more genes compared to the original cell that derives the cell line cell. Some gene mutations may turn on some oncogenes. Cell line cells can be in active culture, stored in a quiescent state for future use (e.g. frozen in liquid nitrogen), or applied in experimental procedures.
term editor: Yongqun He, Matthew Brush, Sirarat Sarntivijai, Alexander Diehl, Jie Zheng, Yu Lin, Bjoern Peters
imported from: clo.owl

immortal cell line cell
type: Class
subclass of: cell line cell
alternative term: permanent cell line cell
definition: A cell line cell that is expected to be capable of an unlimited number of divisions, and is thus able to support indefinite propagation in vitro as part of an immortal cell line.
term editor: Yongqun He, Matthew Brush, Allen Xiang, Asiyah Yu Lin, Sirarat Sarntivijai, James Malone, Jie Zheng, Tomasz Adamusiak
alternative term: continuous cell line cell
imported from: clo.owl

cell line
type: Class
subclass of: BAO_0003114
term editor: MB, SS, JZ, MAH, BP, CS, YH
imported from: clo.owl

293 cell
type: Class
subclass of: immortal cell line cell
alternative term: 293
see also: ATCC: CRL-1573
imported from: clo.owl

293T/17 cell
type: Class
subclass of: immortal cell line cell
see also: ATCC: CRL-11268
alternative term: 293T/17
imported from: clo.owl

A549 cell
type: Class
subclass of: immortal cell line cell
see also: ATCC: CCL-185
see also: HyperCLDB: cl207
alternative term: A549
imported from: clo.owl

ACHN cell
type: Class
subclass of: immortal cell line cell
alternative term: ACHN
see also: ATCC: CRL-1611
imported from: clo.owl

AML12 cell
type: Class
subclass of: immortal cell line cell
see also: ATCC: CRL-2254
alternative term: AML12
imported from: clo.owl

BA/F3 cell
type: Class
subclass of: immortal cell line cell
see also: HyperCLDB: cl5028
alternative term: BA/F3
imported from: clo.owl

BT-549 cell
type: Class
subclass of: immortal cell line cell
see also: ATCC: HTB-122
comment: disease: ductal carcinoma
alternative term: BT-549
imported from: clo.owl

C-33 A cell
type: Class
subclass of: immortal cell line cell
see also: ATCC: HTB-31
alternative term: C-33 A
imported from: clo.owl

CAKI-1 cell
type: Class
subclass of: immortal cell line cell
see also: HyperCLDB: cl623
alternative term: CAKI-1
imported from: clo.owl

Caki-1 cell
type: Class
subclass of: immortal cell line cell
comment: disease: clear cell carcinoma (kidney primary)
alternative term: Caki-1
see also: ATCC: HTB-46
imported from: clo.owl

CCRF-CEM cell
type: Class
subclass of: immortal cell line cell
comment: disease: acute lymphoblastic leukemia
alternative term: CCRF-CEM
see also: ATCC: CCL-119
imported from: clo.owl

CHO cell
type: Class
subclass of: immortal cell line cell
alternative term: CHO
see also: HyperCLDB: cl721
see also: MeSH: D016466
imported from: clo.owl

CHO-K1 cell
type: Class
subclass of: immortal cell line cell
see also: ATCC: CCL-61
alternative term: CHO-K1
imported from: clo.owl

COLO 205 cell
type: Class
subclass of: immortal cell line cell
see also: ATCC: CCL-222
alternative term: COLO 205
comment: disease: colorectal adenocarcinoma (colon primary)
imported from: clo.owl

COS-7 cell
type: Class
subclass of: immortal cell line cell
see also: MeSH: D019556
see also: ATCC: CRL-1651
alternative term: COS-7
imported from: clo.owl

DLD-1 cell
type: Class
subclass of: immortal cell line cell
see also: ATCC: CCL-221
comment: disease: colorectal adenocarcinoma
alternative term: DLD-1
imported from: clo.owl

DU 145 cell
type: Class
subclass of: immortal cell line cell
comment: disease: carcinoma (prostate primary)
see also: ATCC: HTB-81
alternative term: DU 145
imported from: clo.owl

H-4-II-E cell
type: Class
subclass of: immortal cell line cell
comment: disease: hepatoma
see also: ATCC: CRL-1548
alternative term: H-4-II-E
imported from: clo.owl

H69AR cell
type: Class
subclass of: immortal cell line cell
see also: ATCC: CRL-11351
alternative term: H69AR
comment: disease: carcinoma; small cell lung cancer; multidrug resistant
imported from: clo.owl

HCT 116 cell
type: Class
subclass of: immortal cell line cell
see also: MeSH: D045325
alternative term: HCT 116
see also: HyperCLDB: cl1575
see also: ATCC: CCL-247
comment: disease: colorectal carcinoma
imported from: clo.owl

HEL cell
type: Class
subclass of: immortal cell line cell
alternative term: HEL
comment: disease: erythroleukemia
see also: HyperCLDB: cl1585
imported from: clo.owl

HeLa cell
type: Class
subclass of: immortal cell line cell
see also: ATCC: CCL-2
see also: HyperCLDB: cl1601
alternative term: HeLa
see also: MeSH: D006367
imported from: clo.owl

Hep G2 cell
type: Class
subclass of: immortal cell line cell
comment: disease: hepatocellular carcinoma
alternative term: Hep G2
see also: ATCC: HB-8065
imported from: clo.owl

HL-60 cell
type: Class
subclass of: immortal cell line cell
see also: HyperCLDB: cl1684
see also: MeSH: D018922
see also: HyperCLDB: cl1689
comment: disease: promyeloblast; acute promyelocytic leukemia
alternative term: HL-60
see also: ATCC: CCL-240
imported from: clo.owl

Hs 578T cell
type: Class
subclass of: immortal cell line cell
alternative term: Hs 578T
see also: ATCC: HTB-126
comment: disease: ductal carcinoma
imported from: clo.owl

HT-1080 cell
type: Class
subclass of: immortal cell line cell
alternative term: HT-1080
comment: disease: fibrosarcoma
see also: ATCC: CCL-121
imported from: clo.owl

HT-29 cell
type: Class
subclass of: immortal cell line cell
see also: ATCC: HTB-38
alternative term: HT-29
see also: MeSH: D019073
see also: HyperCLDB: cl1752
comment: disease: colorectal adenocarcinoma
imported from: clo.owl

HUV-EC-C cell
type: Class
subclass of: immortal cell line cell
see also: ATCC: CRL-1730
alternative term: HUV-EC-C
imported from: clo.owl

IEC-6 cell
type: Class
subclass of: immortal cell line cell
see also: HyperCLDB: cl1802
alternative term: IEC-6
see also: ATCC: CRL-1592
comment: disease: epithelium
imported from: clo.owl

JURKAT cell
type: Class
subclass of: immortal cell line cell
alternative term: JURKAT
see also: HyperCLDB: cl5296
comment: disease: leukemia, T cell
see also: MeSH: D019169
imported from: clo.owl

MCF7 cell
type: Class
subclass of: immortal cell line cell
comment: disease: adenocarcinoma (mammary gland primary)
see also: ATCC: HTB-22
alternative term: MCF7
imported from: clo.owl

MDA-MB-231 cell
type: Class
subclass of: immortal cell line cell
see also: ATCC: HTB-26
alternative term: MDA-MB-231
comment: disease: adenocarcinoma (mammary gland primary)
imported from: clo.owl

MDCK cell
type: Class
subclass of: immortal cell line cell
see also: HyperCLDB: cl5078
alternative term: MDCK
imported from: clo.owl

MRC-5 cell
type: Class
subclass of: immortal cell line cell
see also: HyperCLDB: cl3564
see also: ATCC: CCL-171
alternative term: MRC-5
imported from: clo.owl

NIH-3T3 cell
type: Class
subclass of: immortal cell line cell
see also: HyperCLDB: cl3710
see also: HyperCLDB: cl3711
alternative term: NIH-3T3
see also: ATCC: CRL-1658
see also: MeSH: D041681
imported from: clo.owl

SH-SY5Y cell
type: Class
subclass of: immortal cell line cell
alternative term: SH-SY5Y
comment: disease: neuroblastoma (brain primary)
see also: ATCC: CRL-2266
imported from: clo.owl

SK-N-SH cell
type: Class
subclass of: immortal cell line cell
see also: ATCC: HTB-11
comment: disease: neuroblastoma (brain primary)
alternative term: SK-N-SH
imported from: clo.owl

THP-1 cell
type: Class
subclass of: immortal cell line cell
comment: disease: acute monocytic leukemia
see also: HyperCLDB: cl4514
alternative term: THP-1
see also: ATCC: TIB-202
imported from: clo.owl

U-2 OS cell
type: Class
subclass of: immortal cell line cell
alternative term: U-2 OS
see also: ATCC: HTB-96
imported from: clo.owl

Vero cell
type: Class
subclass of: immortal cell line cell
see also: HyperCLDB: cl4644
alternative term: Vero
see also: ATCC: CCL-81
see also: MeSH: D014709
imported from: clo.owl

VERO 76 cell
type: Class
subclass of: immortal cell line cell
alternative term: VERO 76
see also: ATCC: CRL-1587
see also: HyperCLDB: cl4655
imported from: clo.owl